Seizures are a disorder caused by structural brain lesions, life-threatening metabolic derangements, or drug toxicity. The present study describes the behavior related to proconvulsant activity induced by thiocolchicoside (TCC) in rats and investigates the electrocorticographic patterns of this behavior and the effectiveness of classic antiepileptic drugs used to control these seizures. Forty-nine adult male Wistar rats were used and divided into two phases of our experimental design: 1) evaluation of seizure-related behavior and electrocorticographic patterns induced by TCC and 2) evaluation of the efficacy of classical antiepileptic drugs to control the proconvulsive activity caused by TCC. Our results showed that TCC induced tonic-clonic seizures that caused changes in electrocorticographic readings, characteristic of convulsive activity, with average amplitude greater than that induced by pentylenetetrazole. Treatment with anticonvulsants, especially diazepam, reduced the electrocorticographic outbreaks induced by TCC. The results suggested that TCC caused seizures with increased power in brain oscillations up to 40 Hz and that diazepam may partially reverse the effects.

This work evaluated different ways to include residues from coffee in Nile tilapia ration. Three assays were conducted: 1-rations chemical composition; 2-digestibility and 3-tilapia performance fed with different ways to include residues of coffee on ration. The following treatments were tested: T1-basal ration; T2-stove pre-dried coffe residue ration; T3-ration with residue from coffee maintained under aerobic conditions added serum of milk and nolasses; T4-ration with acid ensilage of residue from coffee with formic acid; T7-ration with ensilage of residue from coffee with serum of milk. Those residues replaced 30% of the basal ration. The physical form of the ration was pelleted. The treatment T5 resulted in greater weight gain and feed consumption and lesser feed conversion. The treatments T1 and T2 did not defer between itself presenting close values to the T5. The treatments T6 and T7 presented lesser weight gain and ration consumption and greater feed conversion.

O trabalho propôs avaliar formas de inclusão de resíduos de café na ração para alimentação de tilápia do Nilo. Foram realizados três ensaios: 1-composição química das rações; 2-digestibilidade das rações e 3-desempenho de tilápias recebendo as rações contendo diferentes formas de inclusão dos resíduos de café. Foram testados os seguintes tratamentos: T1-ração referência; T2-ração com resíduo de café pré-seco em estufa; T3-ração com resíduo de café mantido em condições aeróbicas acrescido de soro de leite e melaço; T4ração com silagem ácida de resíduo de café com ácido fórmico; T5-ração com silagem de resíduo de café com soro de leite. Esses resíduos substituíram 30% da ração referência, sendo as rações posteriormente peletizadas. O tratamento T5 foi o que resultou em maior ganho de peso e consumo de ração. Os tratamentos T1 e T2 não diferiram entre si, apresentando valores próximos ao T5. Os tratamentos T6 e T7 apresentaram menor ganho de peso e consumo de ração e ainda maior conversão alimentar.