Abstract Objective: To investigate the effectiveness of linezolid and vancomycin for the treatment of nosocomial infections in children under 12 years old. Data sources: This is a systematic review in which five randomized clinical trials about the effectiveness of linezolid and vancomycin, involving a total of 429 children with nosocomial infections, were evaluated. They were searched in scientific databases: PubMed, Bvs, and SciELO. Summary of findings: The main nosocomial infections that affected children were bacteremia, skin, and soft tissue infections followed by nosocomial pneumonia. Most infections were caused by Gram-positive bacteria, which all studies showed infections caused by Staphylococcus aureus, with methicillin-resistant S. aureus (MRSA) and methicillin-resistant coagulase-negative staphylococci strains being isolated. Both linezolid and vancomycin showed high therapeutic efficacy against different types of nosocomial infections, ranging from 84.4% to 94% for linezolid and 76.9% to 90% for vancomycin. Patients receiving linezolid had lower rates of rash and red man syndrome compared to those receiving vancomycin. However, despite the adverse reactions, antimicrobials can be safely administered to children to treat nosocomial infections caused by resistant Gram-positive bacteria. Conclusion: Both linezolid and vancomycin showed good efficacy in the treatment of bacterial infections caused by resistant Gram-positive bacteria in hospitalized children. However, linezolid stands out regarding its pharmacological safety. Importantly, to strengthen this conclusion, further clinical trials are needed to provide additional evidence. Objective 1 old sources 42 evaluated databases PubMed Bvs SciELO findings bacteremia skin pneumonia Grampositive Gram positive methicillinresistant methicillin S MRSA (MRSA coagulasenegative coagulase negative isolated 844 84 4 84.4 94 769 76 9 76.9 90 However reactions Conclusion safety Importantly conclusion evidence 8 84. 7 76.

Riparian forests suffered from forest fragmentation, which in turn promote the change in the pattern of seed dispersion and modification of soil seed bank.nbsp; The aim of this study is to indicate the main species that make up the seed bank of a stretch of riparian forest of the Mogi Guaçu River continued to a fragment of semidecidual forest, located in the Guarnição da Aeronáutica de Pirassununga. It was delimited ten plots of 10 x 10 m. Four soil samples was collected by plot with a 25 x 25 cm template. Samples were packed in greenhouse for seed germination and monitored every 15 days for six months. Altogether, 494 individuals from 19 families were sampled, distributed in 30 genera and 40 morphospecies. Diversity and distribution of species in the fragment is homogeneous and can be used as source of propagules for forest restoration.

Florestas ripárias sofrem com a fragmentação florestal, que promove mudanças no padrão de dispersão de sementes e modificação do banco de sementes. O objetivo do presente estudo é indicar as principais espécies que compõem o banco de semntes de um trecho de floresta ripária do Rio Mogi Guaçu River contínuo a um fragmento de floresta estacional, localizada na Guarnição da Aeronáutica de Pirassununga. Foram delimitadas dez parcelas de 10 x 10 m. Quatro amostras de solo foram coletadas através de um molde de 25 x 25 cm. Amostras foram mantidas em estufa para germinação de sementes e monitoradas a cada 15 dias por seis meses. Ao todo, 494 indivíduos pertencentes a 19 famílias foram amostrados, distribuídos em 30 gêneros e 40 morfoespécies. A diversidade e a distribuição das espécies no fragmento é homogênea, podendo ser usado como uma fonte de propágulos para restauração florestal.

RESUMO Florestas ripárias sofrem com a fragmentação florestal, que promove mudanças no padrão de dispersão de sementes e modificação do banco de sementes. O objetivo do presente estudo é indicar as principais espécies que compõem o banco de semntes de um trecho de floresta ripária do Rio Mogi Guaçu River contínuo a um fragmento de floresta estacional, localizada na Guarnição da Aeronáutica de Pirassununga. Foram delimitadas dez parcelas de 10 x 10 m. Quatro amostras de solo foram coletadas através de um molde de 25 x 25 cm. Amostras foram mantidas em estufa para germinação de sementes e monitoradas a cada 15 dias por seis meses. Ao todo, 494 indivíduos pertencentes a 19 famílias foram amostrados, distribuídos em 30 gêneros e 40 morfoespécies. A diversidade e a distribuição das espécies no fragmento é homogênea, podendo ser usado como uma fonte de propágulos para restauração florestal.

ABSTRACT Riparian forests suffered from forest fragmentation, which in turn promote the change in the pattern of seed dispersion and modification of soil seed bank. The aim of this study is to indicate the main species that make up the seed bank of a stretch of riparian forest of the Mogi Guaçu River continued to a fragment of semidecidual forest, located in the Air Force Base of Pirassununga. It was delimited ten plots of 10 x 10 m. Four soil samples was collected by plot with a 25 x 25 cm template. Samples were packed in greenhouse for seed germination and monitored every 15 days for six months. Altogether, 494 individuals from 19 families were sampled, distributed in 30 genera and 40 morphospecies. Diversity and distribution of species in the fragment is homogeneous and can be used as source of propagules for forest restoration.

RESUMO Objective: Avaliar a experiência dos serviços privado e público de saúde com o procedimento WALANT frente à pandemia COVID-19. Métodos: Trata-se de um estudo longitudinal retrospectivo, multicêntrico, de casos de cirurgia de mão submetidos à técnica WALANT nos hospitais Dr. Radamés Nardini e IFOR, durante a pandemia da COVID-19, em agosto de 2020. Como parâmetro, foi aplicada a Escala Verbal de Dor para 20 pacientes referente ao pré-operatório, intra-operatório e no pós-operatório. Resultados: Os pacientes não sentiram nenhuma dor durante a cirurgia, tendo a técnica anestésica de mostrado eficaz. Conclusão: Pelas análises, foi possível considerar segura e benéfica a técnica WALANT diante da pandemia da COVID-19, que apresenta o diferencial de ser aplicada por um cirurgião ortopédico especialista em mão bem treinado. Nível de Evidência IV, Série de Casos.

ABSTRACT Objective: Evaluate the experience of private and public health services with the WALANT procedure in the COVID-19 pandemic. Methods: This is a retrospective, multicenter longitudinal study gathering cases of hand surgery subjected to the WALANT technique in the Hospitals Dr. Radamés Nardini and IFOR during the COVID-19 pandemic (August 2020). As a parameter, the verbal numerical rating scale for twenty patients referring to the preoperative, intraoperative and postoperative periods was applied. Results: The patients did not feel any pain during surgery, which showed the efficiency of the anesthetic technique in its purpose. Conclusion: The results indicate the WALANT technique as beneficial when facing the COVID-19 pandemic, as the main differential of the technique is that it is applied by a well-trained orthopedic hand surgeon. Level of Evidence IV, Case Series.

Resumo Introdução: O Rhinitis Control Assessment Test (RCAT) é um questionário simples e autoaplicável desenvolvido para avaliar o controle da rinite. Objetivos: Traduzir para o Português validar o RCAT. Método: A tradução do RCAT foi feita por dois tradutores com posterior versão para a Língua Inglesa. O RCAT foi então aplicado de forma transversal a 141 adolescentes com rinite alérgica. Resultados: A consistência interna do RCAT foi 0,73. As notas totais do questionário se correlacionaram significantemente com os escores de sintomas nasais e extra-nasais e pico de fluxo inspiratório nasal (r: -0,73, -0,58 e 0,52, respectivamente; p < 0,001) e foram significantemente diferentes quando separadas pela opinião médica sobre o controle da rinite e pela gravidade dos sintomas nasais. Os pontos de corte entre 22 e 24 foram os com maiores áreas sob a curva ROC para definição do controle da rinite. Os escores de sintomas nasais e extra-nasais foram significantemente diferentes quando os pacientes foram separados pelo ponto de corte de 22 (medianas de 4,0 vs. 8,0 e 2,0 vs. 5,0; p < 0,001). Conclusões: A versão em Português do RCAT se mostrou uma ferramenta válida e com bom poder discriminativo para separar pacientes com rinite alérgica controlada e não controlada.

Abstract Introduction: The Rhinitis Control Assessment Test (RCAT) is a simple self-administered questionnaire developed to assess control of rhinitis. Objectives: Translate into Brazilian Portuguese and validate the RCAT. Methods: The RCAT was translated into Portuguese by two translators and subsequently back-translated into English. It was then applied to 141 adolescents with allergic rhinitis. Results: The internal consistency of the RCAT was 0.73. The questionnaire scores showed significant correlation with total nasal and extra-nasal symptom scores and nasal peak inspiratory flow (r: −0.73, −0.58 and 0.52, respectively; p < 0.001) and were significantly different when divided by physician global assessment and total nasal symptom score severity. Cutoff points between 22 and 24 had the higher areas under the ROC curve to identify patients with rhinitis control. Total nasal and extra-nasal symptom scores were significantly different when a cutoff point of 22 was used (median: 4.0 vs. 8.0 and 2.0 vs. 5.0; p < 0.001). Conclusions: The Brazilian Portuguese version of the RCAT was shown to be a valid and discriminant tool to identify patients with controlled and uncontrolled allergic rhinitis.