The history of the discovery, use, and development of dyes is closely linked to the history of humanity itself. Among the first records of human civilization are cave paintings made from, e.g., fruits, plants, minerals, and insects. Over the centuries, using different techniques, colors have been given to all types of materials and products, from clothing to food. The chemicals responsible for colors are dyes - a vast collection of molecules of the most varied compositions, but which have in common the absorption of light within the visible window of the electromagnetic spectrum. This article aims not only to review the properties of some classes of natural dyes, their origins, and their applications but also to describe the various computational chemistry methods involved in designing new bio-inspired molecules. discovery use itself eg e g e.g. fruits plants minerals insects centuries techniques products food compositions spectrum origins bioinspired bio inspired e.g

Abstract A new early Eocene, small-sized metatherian from the Itaboraí fauna is described. The new taxon is recognized on the basis of an incomplete dentary recovered from fissure fillings in the travertine limestones from the Itaboraí Basin, State of Rio de Janeiro, Brazil. The phylogenetic analysis placed the new genus and species as the sister taxon of Derorhynchus, undescribed Derorhynchidae, and Coona plus Pauladelphys. When compared to Derorhynchus, the new taxon exhibits a shorter dentary, in which the first lower premolar is not separated from the second by a diastema, and shows second and third lower molars with subequal trigonid and talonid width (in Derorhynchus the talonids are wider than the trigonids). This new taxon shows some plesiomorphic traits when compared with the remaining derorhynchids, such as the shallower dentary (less than 1.5 mm), and conical entoconids rather than flattened in shape. The combination of very small size (~13-20g), sharp crests, tall and slender cuspids, broad talonid basins, as well as trigonid taller than the talonid is suggestive of an insectivorous diet for the new taxon.

Abstract The Protodidelphidae was a group of marsupials that lived in Gondwana from the early to middle Eocene. Among South American faunas, the Itaboraí Basin calls attention by the presence of four genera and six species. Herein is described Bergqvistherium primigenia gen. et sp. nov., a new protodidelphid from the Itaboraí Basin - lower Eocene. This taxon differs from other protodidelphids in the smaller size, developed entocristid, less brachyo-bunoid adaptations, and entoconid more mesial than the hypoconid. These characters are recovered as plesiomorphies of the Protodidelphidae, supporting Bergqvistherium as an early-divergent lineage of this group. The Protodidelphidae fauna of the Itaboraí Basin is represented by less specialized “basal” taxa, such as Bergqvistherium and Periprotodidelphis; and more specialized apical taxa, such as Guggenheimia, Protodidelphis, and Carolocoutoia. This result indicates that the diversification of apical protodidelphids probably was a result of a relatively short-time event, occurring during the early Eocene. This evolutionary event can be directly correlated to the increase in the temperatures and the extension of tropical forests resulted by the Paleocene-Eocene Thermal Maximum during the Itaboraiense time span. The study supported a Late Cretaceous origin for the Protodidelphidae, which agrees with molecular studies for the Didelphimorphia.