A violência é um problema de saúde pública e sua notificação é fundamental para a vigilância epidemiológica e para a definição de políticas públicas de prevenção e promoção de saúde. O estudo objetivou caracterizar a ocorrência de violência doméstica, sexual e de outras, a partir das informações do banco de dados do Sistema Informação de Agravos de Notificação (SINAN), das fichas de notificação de violência da cidade de Belém (PA), no período de janeiro de 2009 a dezembro de 2011. Foram sistematizadas 3.267 notificações, representando um aumento de 240% de 2009 a 2011. Em relação ao sexo das vítimas, observou-se que, em média, 83,2% dos casos atingiram as mulheres, proporção esta semelhante nos três anos analisados. A violência sexual foi a mais presente com 41,8%; seguida da violência psicológica com 26,3% e da violência física com 24,0%. Os resultados demonstram a importância do conhecimento do perfil das violências para intervenção e elaboração de políticas públicas intersetoriais que promovam a saúde e a qualidade de vida nesta região do Brasil.

Violence is a serious public health problem and notification of incidents is fundamental for epidemic surveillance and for the definition of priorities and public politics of health prevention and promotion. The study sought to characterize the occurrence of domestic violence, sexual and other forms of violence, based on the information of the database of the Information System of Notification of Offences (Sinan), on the records of violence of the city of Belém in the state of Pará, in the period from January 2009 to December 2011. In this period 3,267 notifications were recorded, which represented an increase of 240% in the number of notifications of the year 2009 compared to 2011. In relation to the sex of the victims it was observed that, on average, 83.2% of cases against women and this proportion was similar in all three years analyzed. Sexual violence was the most prevalent with 41.8% of reported cases; followed by psychological violence at 26.3% and physical violence at 24%. The results show that notification is fundamental for understanding the profile of violence and for intervention and elaboration of integrated public politics that promote health and the quality of life in this area of Brazil.

A violência é um problema de saúde pública e sua notificação é fundamental para a vigilância epidemiológica e para a definição de políticas públicas de prevenção e promoção de saúde. O estudo objetivou caracterizar a ocorrência de violência doméstica, sexual e de outras, a partir das informações do banco de dados do Sistema Informação de Agravos de Notificação (SINAN), das fichas de notificação de violência da cidade de Belém (PA), no período de janeiro de 2009 a dezembro de 2011. Foram sistematizadas 3.267 notificações, representando um aumento de 240% de 2009 a 2011. Em relação ao sexo das vítimas, observou-se que, em média, 83,2% dos casos atingiram as mulheres, proporção esta semelhante nos três anos analisados. A violência sexual foi a mais presente com 41,8%; seguida da violência psicológica com 26,3% e da violência física com 24,0%. Os resultados demonstram a importância do conhecimento do perfil das violências para intervenção e elaboração de políticas públicas intersetoriais que promovam a saúde e a qualidade de vida nesta região do Brasil.

Violence is a serious public health problem and notification of incidents is fundamental for epidemic surveillance and for the definition of priorities and public politics of health prevention and promotion. The study sought to characterize the occurrence of domestic violence, sexual and other forms of violence, based on the information of the database of the Information System of Notification of Offences (Sinan), on the records of violence of the city of Belém in the state of Pará, in the period from January 2009 to December 2011. In this period 3,267 notifications were recorded, which represented an increase of 240% in the number of notifications of the year 2009 compared to 2011. In relation to the sex of the victims it was observed that, on average, 83.2% of cases against women and this proportion was similar in all three years analyzed. Sexual violence was the most prevalent with 41.8% of reported cases; followed by psychological violence at 26.3% and physical violence at 24%. The results show that notification is fundamental for understanding the profile of violence and for intervention and elaboration of integrated public politics that promote health and the quality of life in this area of Brazil.

Physalis angulata L (Solanaceae) is a medicinal plant from North of Brazil, whose different extracts and infusions are commonly used in the popular medicine for the treatment of malaria, asthma, hepatitis, dermatitis and rheumatism. However, the genotoxic effects of P. angulata on human cells is not well known. The main purpose of the present study was to evaluate the in vitro genotoxic effects of aqueous extract of P. angulata using the comet assay and the micronucleus assay in human lymphocytes provided from 6 healthy donors. Treatments with P. angulata extracts were performed in vitro in order to access the extent of DNA damage. The comet assay has shown that treatments with P. angulata at 0.5, 1.0, 2.0, 3.0 and 6.0 μg/mL in culture medium were genotoxic. Lymphocytes treated with P. angulata at the concentrations of 3.0 and 6.0μg/mL in culture medium showed a statistically significant increase in the frequency of micronucleus (p<0.05), however, the cytokinesis blocked proliferation index (CBPI) was not decreased after P. angulata treatment. In conclusion, the present work demonstrated the genotoxic effects of P. angulata extract on human lymphocytes in vitro.