Abstract A middle-aged female patient with a tibial plateau fracture combined with an avulsion of the tibial eminence was treated with a combination of medial plate fixation for the plateau and an arthroscopic aided nonabsorbable suture of the eminence. Our technique for tibial eminence avulsion fractures has no interference with tibial plateau osteosynthesis materials and has proven, once again, to have good results in the treatment of combined and complex injuries of the knee. middleaged middle aged proven again knee

Resumo Uma paciente de meia-idade com fratura do platô tibial e avulsão da eminência tibial foi tratada com uma combinação de fixação do platô com placa medial e sutura da eminência com fio não absorvível auxiliada por artroscopia. Nossa técnica para fraturas com avulsão da eminência tibial não interfere nos materiais de osteossíntese do platô tibial e, mais uma vez, teve bons resultados no tratamento de lesões combinadas e complexas do joelho. meiaidade meia idade artroscopia vez joelho

Abstract Neospora caninum is a major cause of reproductive loss in cattle worldwide as it leads to abortion and animal repositioning. Although Toxoplasma gondii does not cause a reproductive problem in cattle, consuming raw or uncooked beef poses the risk of transmission. This study aimed to evaluate the occurrence of anti-N. caninum and anti-T. gondii antibodies in dairy cattle in the West and Northwest regions of São Paulo State, Brazil. A total of 653 serum samples from dairy cows were analyzed using an indirect immunofluorescence assay (IFA). Epidemiological data from the farms were associated with the serological results of the animals by logistic regression based on the presence of antibodies. The frequencies of the antibodies against N. caninum and T. gondii were 41.6% (272/653) and 11.5% (75/653), respectively. A statistically significant association was observed between: the serum anti-N. caninum antibodies and breed, history of food supplementation for calves, introduction of outside animals that later presented reproductive problems, and history of reproductive problems by the trimester of gestation. The present study highlights the importance of neosporosis in dairy cattle in the study regions and that the inclusion of this parasite in the investigation of animals with reproductive disorders is important. repositioning transmission antiN. antiN anti N anti-N antiT. antiT T anti-T State Brazil 65 IFA. IFA . (IFA) 416 41 6 41.6 272/653 272653 272 (272/653 115 11 5 11.5 75/653, 75653 75/653 , 75 (75/653) respectively between breed calves gestation important (IFA 4 41. 272/65 27265 27 (272/65 1 11. 7565 75/65 7 (75/653 272/6 2726 2 (272/6 756 75/6 (75/65 272/ (272/ 75/ (75/6 (272 (75/ (27 (75 (2 (7 (

Resumo Neospora caninum é uma das principais causas de perda reprodutiva em bovinos em todo o mundo, pois leva ao aborto e ao reposicionamento animal. Embora o Toxoplasma gondii não cause problemas reprodutivos em bovinos, o consumo de carne bovina crua ou não cozida apresenta risco de transmissão. Este estudo teve como objetivo avaliar a ocorrência de anticorpos anti-N. caninum e anti-T. gondii em bovinos leiteiros nas regiões Oeste e Noroeste do Estado de São Paulo, Brasil. Um total de 653 amostras de soro de bovinos leiteiros, foi analisado utilizando-se o ensaio de imunofluorescência indireta (IFI). Os dados epidemiológicos das propriedades foram associados aos resultados sorológicos dos animais por meio de regressão logística. As frequências dos anticorpos contra N. caninum e T. gondii foram 41,6% (272/653) e 11,5% (75/653), respectivamente. Foi observada associação estatisticamente significativa entre: soropositividade para N. caninum e raça, histórico de suplementação alimentar para bezerros, introdução de animais externos que, posteriormente, apresentaram problemas reprodutivos e histórico de problemas reprodutivos no segundo trimestre de gestação. O presente estudo destaca a importância da neosporose em bovinos leiteiros, nas regiões de estudo, e a inclusão deste parasita na investigação de animais com distúrbios reprodutivos é fundamental. mundo animal transmissão antiN. antiN anti N anti-N antiT. antiT T anti-T Paulo Brasil 65 utilizandose utilizando se IFI. IFI . (IFI) logística 416 41 6 41,6 272/653 272653 272 (272/653 115 11 5 11,5 75/653, 75653 75/653 , 75 (75/653) respectivamente entre raça bezerros que posteriormente gestação fundamental (IFI 4 41, 272/65 27265 27 (272/65 1 11, 7565 75/65 7 (75/653 272/6 2726 2 (272/6 756 75/6 (75/65 272/ (272/ 75/ (75/6 (272 (75/ (27 (75 (2 (7 (

Abstract The present article analyzed the process of precarious work relations in the health sector, demonstrating how this situation generated illness and suffering among workers. The text sought to register how the institutional adoption of neoliberal economic conceptions, of the reduction of State social policies, coupled with a history of cultural rejection of labor rights, provided the attraction of mechanisms of precarious work for the public sector, notably, the outsourcing of labor and the provision of services. In a second moment, the text points out the legal improprieties committed, presenting the consequences of the weakening of the legal bond in the working conditions of these workers, mainly regarding working hours and remuneration, also highlighting how much the dissemination of these links represented a factor of a general reduction in wages and labor and social security rights in the sector. Data from Fiocruz surveys on working conditions during the pandemic were also presented. The article concludes by showing the urgency of rescuing the legal labor institutes that were abandoned in the historical path studied in order to guide the public health policies in a new direction. sector workers conceptions notably services moment committed remuneration presented direction

Resumo O artigo analisou o processo de precarização das relações de trabalho no setor da saúde, demonstrando como essa situação gerou sofrimento dos trabalhadores. O texto buscou registrar como a adoção institucional das concepções econômicas neoliberais, de redução das políticas sociais de Estado, acopladas a um histórico de rejeição cultural aos direitos trabalhistas, proporcionou a atração dos mecanismos de precarização do trabalho, notadamente, a terceirização da mão de obra e da prestação de serviços. No segundo momento, o texto aponta as impropriedades jurídicas cometidas, apresentando as consequências da fragilização do vínculo jurídico nas condições de trabalho desses trabalhadores, principalmente no que se refere às jornadas de trabalho e a remuneração, destacando-se, também, o quanto a disseminação desses vínculos representou um fator de rebaixamento geral dos salários e direitos trabalhistas e previdenciários no setor. Foram apresentados, ainda, dados das pesquisas da Fiocruz sobre condições de trabalho durante a pandemia. Conclui mostrando a urgência de se resgatarem os institutos jurídicos trabalhistas que foram abandonados no percurso histórico estudado, para direcionar a novo rumo as políticas públicas na saúde. saúde trabalhadores neoliberais Estado notadamente serviços momento cometidas remuneração destacandose, destacandose destacando se, destacando-se também apresentados ainda pandemia estudado

Resumo O artigo analisou o processo de precarização das relações de trabalho no setor da saúde, demonstrando como essa situação gerou sofrimento dos trabalhadores. O texto buscou registrar como a adoção institucional das concepções econômicas neoliberais, de redução das políticas sociais de Estado, acopladas a um histórico de rejeição cultural aos direitos trabalhistas, proporcionou a atração dos mecanismos de precarização do trabalho, notadamente, a terceirização da mão de obra e da prestação de serviços. No segundo momento, o texto aponta as impropriedades jurídicas cometidas, apresentando as consequências da fragilização do vínculo jurídico nas condições de trabalho desses trabalhadores, principalmente no que se refere às jornadas de trabalho e a remuneração, destacando-se, também, o quanto a disseminação desses vínculos representou um fator de rebaixamento geral dos salários e direitos trabalhistas e previdenciários no setor. Foram apresentados, ainda, dados das pesquisas da Fiocruz sobre condições de trabalho durante a pandemia. Conclui mostrando a urgência de se resgatarem os institutos jurídicos trabalhistas que foram abandonados no percurso histórico estudado, para direcionar a novo rumo as políticas públicas na saúde.

Abstract The present article analyzed the process of precarious work relations in the health sector, demonstrating how this situation generated illness and suffering among workers. The text sought to register how the institutional adoption of neoliberal economic conceptions, of the reduction of State social policies, coupled with a history of cultural rejection of labor rights, provided the attraction of mechanisms of precarious work for the public sector, notably, the outsourcing of labor and the provision of services. In a second moment, the text points out the legal improprieties committed, presenting the consequences of the weakening of the legal bond in the working conditions of these workers, mainly regarding working hours and remuneration, also highlighting how much the dissemination of these links represented a factor of a general reduction in wages and labor and social security rights in the sector. Data from Fiocruz surveys on working conditions during the pandemic were also presented. The article concludes by showing the urgency of rescuing the legal labor institutes that were abandoned in the historical path studied in order to guide the public health policies in a new direction.

Abstract Background and objective. In 2017, the Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery instrument for detection of Body Dysmorphic Disorder in patients seeking cosmetic rhinoplasty was validated in English. In this context, the objective of this study was to carry out the linguistic and cultural adaptation and reliability of the Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery instrument to the Spanish-speaking Colombian context. Methods. The Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery instrument was translated from English to Spanish in accordance with international guidelines. For the application of the Spanish version, candidates for rhinoplasty for the first time older than 18 years and control subjects matched by sex and age who attended a private consultation between April 1 to 30, 2020 were included. Results. The Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery instrument was translated and adapted for use in a Spanish-speaking population. Good consistency was obtained with a Cronbach's alpha coefficient of 0.89. Conclusions. The Spanish version of the Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery instrument obtained proved to be understandable and adapted for use in Colombia. Its ease of use makes it a potentially useful tool.

Resumen Introducción y objetivo. En 2017 se validó en inglés el Cuestionario de Trastorno Dismórfico Corporal - Cirugía Estética para detección de trastorno dismórfico corporal en pacientes que buscan rinoplastia estética. En este contexto, el objetivo de este estudio fue realizar la adaptación lingüística y cultural del Cuestionario de Trastorno Dismórfico Corporal -Cirugía Estética al contexto hispanohablante y validarlo en el ámbito colombiano. Material y método. El Cuestionario de Trastorno Dismórfico Corporal - Cirugía Estética se tradujo del inglés al español de acuerdo con las guías internacionales. Para la aplicación de la versión en español se incluyeron candidatos colombianos a rinoplastia primaria mayores de 18 años y sujetos control pareados por sexo y edad que asistieron a consulta particular entre el 1 al 30 de abril de 2020. Resultados. Obtuvimos la versión en español del Cuestionario de Trastorno Dismórfico Corporal - Cirugía Estética adaptada al contexto colombiano y con evaluación de consistencia interna. La consistencia fue buena con un coeficiente de Alfa de Cronbach de 0.89. Conclusiones. La versión en español para hispanohablantes del Cuestionario de Trastorno Dismórfico Corporal - Cirugía Estética obtenida ha mostrado ser comprensible y adaptada para su uso en Colombia. Su facilidad de uso la convierte en una herramienta potencialmente útil.

Abstract In this paper, the crystallization, fusion, and activation energy (Ea) of PBT/TiO2 were thoroughly evaluated using DSC. Increasing the rates shifted the peaks of melt crystallization to lower temperatures while the fusions were almost unaffected. TiO2 hindered the melt crystallization of PBT and lower crystallization rates, i.e., CMAX and K’ were acquired, in general, the crystallinity degree (Xc) was 4% higher in PBT/TiO2 which is in the marginal error. Pseudo-Avrami and Mo models were applied to evaluate the melt crystallization kinetics; both fitted the melt crystallization quite well; deviations were observed at the beginning and the crystallization end most due to the nucleation and spherulites impingement during the secondary crystallization. Ea was evaluated using the Friedman model, considering the values of Ea less energy has to be removed from PBT/TiO2 when compared to PBT, specifically at 1% of TiO2. paper fusion (Ea PBTTiO2 PBTTiO TiO PBT/TiO DSC unaffected ie i e i.e. K acquired general Xc (Xc 4 error PseudoAvrami Pseudo Avrami kinetics well model 1 i.e

RESUMO: Lesões podais em ovinos são responsáveis por grandes perdas econômicas, pois a dor durante a locomoção interfere na alimentação e no comportamento, levando à perda de produtividade. O objetivo deste trabalho foi descrever as principais doenças podais encontradas em rebanho ovino, que utiliza medidas profiláticas contra as doenças podais. Foram examinadas 346 ovelhas quanto à presença de lesões podais em todos os membros, dígitos e estruturas adjacentes. Entre os 2.768 dígitos avaliados, 103 (29,76%) apresentavam lesões, representando 1,04 lesões por animal. 41,75% (43/103) apresentavam apenas uma lesão, 39,81% (41/103) tinham duas lesões, 16 (15,53%) tinham três lesões, e apenas três animais apresentavam quatro ou mais lesões. Os membros posteriores foram os mais afetados e as doenças mais frequentes foram a doença da linha branca (40,05%), dermatite interdigital (33,70%) e footrot (12,15%). Pode-se concluir que as lesões podais em ovinos são frequentes e constituem um problema sanitário para os rebanhos, mesmo em propriedade que realiza medidas profiláticas. Portanto, é fundamental classificar as lesões, assim como adotar as medidas profiláticas e terapêuticas eficazes.

ABSTRACT: Foot lesions in sheep herds are responsible for great economic losses, because pain during locomotion interferes with feeding and behavior, leading productivity losses. The objective of this work was to describe the main foot disease found in sheep herd that uses prophylactic measures against foot diseases. A total of 346 ewes of different ages, with or without lameness, were assessed for the presence of foot lesions in all limbs, digits and adjacent structures. Among all the 2768 digits evaluated, 103 (29.76%) had lesions, representing 1.04 lesion per animal. 41.75% (43/103) had only one lesion, 39.81% (41/103) had two lesions, 16 (15.53%) had three lesions, and only 2.91% (3/103) had four or more lesions. Hind limbs were the most affected and the most frequent diseases were white line disease (40.05%), interdigital dermatitis (33.70%) and footrot (12.15%). It was concluded that foot disease in sheep is frequent and constitute a health problem for herds, even on farms that use strategies to prevent it. Therefore, it is essential to classify the lesions, as well as the adoption of effective prophylactic and therapeutic measures.

ABSTRACT In Fortaleza, the capital of Ceara State, Brazil, the detection rate of tuberculosis (TB) in 2018 was 65.5/100,000 inhabitants with a cure rate of 59.1%, which is higher than the country average. This study investigated the risk factors associated with drug-resistant tuberculosis (DR-TB) and identified the drug-resistance phenotype and resistance-conferring mutations. The geographic distribution of DR-TB in Fortaleza, Brazil, was also determined. From March 2017 to February 2018, 41 DR-TB isolates and 69 drug-susceptible pulmonary TB isolates were obtained from patients seen at a referral hospital in Fortaleza, Brazil. Samples were subjected to phenotypic and genetic analysis of resistance; the spatial distribution of the participants was also analyzed. Primary resistance was high (50.9%) among participants. The following risk factors for DR were identified: being female ( p = 0.03), having diabetes ( p < 0.01), history of previous TB disease ( p < 0.01), and the number of intra-domiciliary contacts ( p < 0.01). Analysis by multiplex allele-specific polymerase chain reaction detected mutations in the genes katG (65.8%) , rpoB (43.9%), inhA promoter (14.6%), and gyrA (9.8%). Sequencing identified mutations in the the genes katG (75.6%), inhA promoter (19.5%), rpoB (85.4%), and gyrA (100%). There was no mutation in the rrs gene. Spatial analysis showed DR-TB isolates distributed in areas of low socioeconomic status in the city of Fortaleza. Our results emphasized the importance of detecting resistance to TB drugs. The resistance found in the gene gyrA is of concern due to the high number of pre-extensive DR-TB cases in Fortaleza.

Abstract The understanding of parasitic diseases begins by knowing the species of a population. Accordingly, information to identify the equine helminth faunas of Cuba was re-collected due to the gradual loss of data caused by deterioration of the printed scientific literature. These parasitic populations were first identified by Doctor Idelfonso Pérez Vigueras during the first half of the 21st Century. Further studies were conducted on horse populations in different provinces. Currently, 34 helminths have been properly reported, including nine benzimidazole-resistant species of cyathostomes in several herds. As a result of a large number of nematodes described in the international scientific literature, and due to the insufficient studies made in Cuba, the equine helminth faunas probably include a larger number of species. Hence, further comprehensive studies should be conducted on this topic.

Resumen La comprensión de las enfermedades parasitarias, comienza por el conocimiento de las especies presentes en una población. Debido a la pérdida paulatina por deterioro de las fuentes bibliográficas impresas, se procedió a recopilar información sobre la identificación de la helmintofauna equina de Cuba. Estas poblaciones de parásitos comenzaron a ser identificada por el doctor Idelfonso Pérez Vigueras a mediados de la primera mitad del siglo xx. Posteriormente otros trabajos fueron realizados en poblaciones de caballos en diferentes provincias. Hasta el momento un total de 34 helmintos se encuentran debidamente reportados. Entre los cuales nueve especies de ciatostomas resultaron resistentes a los benzimidazoles en varios rebaños del País. Como consecuencia del gran número de especies de nematodos descritos en los últimos años en la literatura internacional y lo poco estudiado del tema en Cuba, es muy probable que la helmintofauna equina en el país esté compuesta por un mayor número de especies. Por lo cual, se requiere realizar estudios más abarcadores del tema.

ABSTRACT The objective of this study was to evaluate the reproductive performance of ewes subjected to a short-term protocol for estrus induction using 1 mg of Norgestomet during the non-breeding season in Brazil. A total of 84 ewes were randomly divided into two equal groups (n = 42 per group). Controlled Internal Drug Release (CIDR) containing 330 mg progesterone was inserted into the vagina in the first 42 ewes, and for the other 42 ewes in the second group, 1 mg of Norgestomet was placed subcutaneously in the convex surface of the ear. Implants and devices were removed in both groups on day 6. Following the removal of implants and devices, 10 mg of PGF2α and 300 IU of eCG were injected in all the ewes. After 48 h of application, three fertile rams were added to the herd. Ewes and rams were kept together for four days. Rams were removed on day 12, and after 42 days, pregnancy was diagnosed by ultrasound scanning. Short-term protocols using either an intravaginal device or ear implant were similarly effective to estrus induction (95.23 vs. 92.85%), and all ewes from both groups had estrus manifestation within 72 h after implant removal (72±9 h). In addition, no significant difference in pregnancy rate was observed between ewes treated with the intravaginal device and ear implant protocols (52.38 vs. 57.14%). These results suggest that 1 mg of Norgestomet is a good alternative for short-term protocols for estrus induction/synchronization during the non-breeding season in ewes. It is possible to replace the progesterone-releasing intravaginal device by the ear implant and obtain the same reproductive effectiveness in ewes.

RESUMO O presente trabalho apresenta a análise de um elemento não convencional para sistema vedação de edificações: o bloco de concreto prensado com a incorporação de PET reciclado. Para tanto foi realizada uma análise experimental realizando-se a substituição, em volume, do agregado miúdo (pó de pedra) por PET triturado, nos teores de 15%, 30% e 45%. Foram determinados características geométricas, índices físicos e características mecânicas dos blocos produzidos. Os resultados obtidos permitem concluir que os blocos que apresentaram os melhores resultados foram os com 15% de PET, uma vez que a sua resistência à compressão apresentou valor maior que a dos demais, destacando ainda uma menor absorção, resultantes possivelmente do maior grau de empacotamento e melhor homogeneidade do compósito obtido.

ABSTRACT This work shows the analysis of a no conventional element for building sealing system: a pressed concrete block incorporating recycled PET. For this it was made an experimental analysis replacing, in volume, fine aggregate (fine crushed stone) by fractions of crushed PET in contents of 15%, 30% and 45%. Were determined geometrical, physical and mechanical characteristics indexes of produced blocks. Results allow to conclude that the content that showed the best results was 15% of PET because its compressive strength showed a value greater than the others, highlighting even lower absorption, resulting from its higher homogeneity and better wrapping of the obtained composite.

RESUMO A presente revisão objetivou apresentar os principais aspectos relacionados à infecção causada pelo vírus da língua azul em ovinos. A língua azul é uma doença viral, infecciosa e não contagiosa, causada por um vírus (BTV) do gênero Orbivírus, transmitida por meio de vetores hematófagos do gênero Culicoides a ruminantes domésticos e selvagens, principalmente aos ovinos, a espécie mais susceptível. A infecção ocorre de forma endêmica, associada a condições climáticas com elevada temperatura e umidade. As perdas econômicas estão ligadas diretamente à morte, ao abortamento, à perda de peso, à perda na produção de leite e carne, e, indiretamente, devido à restrição na exportação de animais e seus subprodutos. O estudo conclui que a língua azul está disseminada mundialmente e persiste, provavelmente, devido ao clima quente e úmido que propicia a proliferação de Culicoides sp., sendo necessário adotar medidas que diminuam os fatores de risco associados à infecção pelo vírus.

ABSTRACT The present review aims to show the main aspects related to bluetongue virus (BTV) infection in sheep. The bluetongue (BT) is a viral, infectious, and non-contagious disease caused by a virus (BTV) of the Orbivirus genus, transmited by a hematophagous vector of the Culicoides genus, to domestic and wild ruminants, mainly to sheep, the most susceptible species. It is caused by the association of endemic with climate conditions, with high temperatures and humidity. Economic loss is directly linked to death, abortion, weight loss, loss of milk, and meat production, and, indirectly, to the restriction on the export of animals and their by-products. The study concludes that the BTV is worldwidely spread, and probably persists due to the warm and humid climate that leads to the proliferation of Culicoides sp., being necessary to adopt measures that reduce the risk factors associated to the BTV infection.

O objetivo do trabalho foi verificar possíveis efeitos alelopáticos exercidos por extratos aquosos de folhas de cumaru (Amburana cearensis) e malva-santa (Plectranthus barbatus) sobre a germinação de sementes de caruru (Amaranthus deflexus). As sementes de caruru foram colocadas para germinar em placas de petri em contato com extratos vegetais aquosos obtidos a partir de folhas de cumaru e malva-santa sob dois métodos de preparação - extrato aquoso das folhas frescas e extrato aquoso por infusão das folhas secas - e duas dosagens - 50 e 100 g L-1. Foi utilizado o delineamento inteiramente casualizado com 4 repetições e uma testemunha isolada compondo um fatorial 2 x 2 x 2 + 1. Foi determinada a porcentagem final e o índice de velocidade de germinação. A análise dos dados revelou diferença entre os tratamentos e a testemunha, condicionando graus diferentes de alelopatia para os extratos usados afetando drasticamente a germinação do caruru. O extrato a base de folhas frescas de cumaru apresenta alto nível de alelopatia de modo a impedir quase que completamente a germinação do caruru. A dose, com efeito, mais prejudicial para a germinação do caruru foi a de 100 g L-1.

The objective was to verify possible allelopathic effects exerted by aqueous extracts of leaves of Amburana cearensis and Plectranthus barbatus on the seed germination of the weed Amaranthus deflexus.A. deflexus seeds were put to germinate in Petri plates containing aqueous plant extracts obtained from A. cearensis and P. barbatus leaves under two tillage methods - aqueous extract from fresh leaves and aqueous extract by infusion of dried leaves - and two dosages - 50 and 100 g L-1. We used a completely randomized design with 4 replications and a detached witness composing a factorial 2 x 2 x 2 + 1. It was determined the final percentage and germination speed index. Data analysis revealed differences between treatments and the witness, conditioning different allelopathy levels for the extracts used, dramatically affecting the germination of A. deflexus. The A. cearensis fresh leaves extracts has a high level of allelopathy since they prevent almost completely the germination of the weed A. deflexus. The most damaging dosage for germination of A. deflexus was 100 g L-1.

Coxiella burnetii (C. burnetii) causes a zoonotic disease - Q fever. This bacterium is highly resistant to harsh environmental conditions and causes an uncharacteristic clinical syndrome. Q fever may be acute or chronic and renal manifestations of the disease are more common in the chronic forms. It is reported a case of a 83 -year old woman, with previous normal renal function and a medical history of arterial hypertension and osteoarthritis. She presented with leg oedema, acute kidney injury (serum creatinine 4.14 mg/dl), and an urine protein-to-creatinine ratio of 9.14 gr/gr. A diagnosis of acute kidney injury with nephrotic syndrome was admitted. The lab work revealed a decrease in serum complement levels (C3, C4), and elevated serum levels of β2 -microglobulin and IgM anticardiolipin. Renal ultrasound showed bilateral cysts, so a renal biopsy could not be performed. During hospital stay, renal function worsened with oliguria and the patient needed transient haemodialysis. The renal function gradually recovered but the nephrotic syndrome (ratio 18gr/gr) persisted, with a thrombotic complication (deep vein thrombosis and pulmonary emboli). She presented a fever of unknown origin (FUO) and was treated with several antibiotic courses, eventually becoming afebrile. She was discharged with a serum creatinine 0,89mg/dL and a proteinuria of 18g/24H. By then, we had obtained the result of a positive serology for C. burnetii, so doxycycline was started and proteinuria (0,3gr/gr) remitted. Currently, the patient remains with high levels of C. burnetii antibodies and is still under treatment with doxycycline. The authors report a case of acute Q fever manifested by recurrent fever and acute kidney injury with nephrotic syndrome. This case illustrates a rare aetiology of nephrotic syndrome with acute kidney injury