RESUMEN Un deslizamiento de tierra catastrófico afectó el Monte Fugui, de la localidad Diexi, en el condado Mao de la provincia china de Sichuan, a las 05:38:58 hora local del 24 de junio de 2017. Este deslizamiento enterró la población de Xinmo, causó 83 muertos y significó enormes pérdidas de propiedades. La masa del deslizamiento se desprendió en lo alto de la montaña, se continuó cargando y se acumuló en la parte alta de la pendiente. Seguidamente, la masa del deslizamiento se transformó en una avalancha de detritos. Esta fue una cadena típica de un desastre ocasionado por una avalancha de detritos que comenzó por un deslizamiento en lo alto de la montañana. El volumen total, la diferencia de elevación y la distancia horizontal del deslizamiento fueron de 1637.6 χ 104 m3, 1200 m, and 2800 m. En este trabajo se identificó el mecanismo de formación del deslizamiento de Xinmo con base en un estudio de campo geológico y con el apoyo de satélites de teledetección. Los autores simularon numéricamente las características del desastre en la zona fuente, en la zona de la avalancha y en la zona de acumulación. Todo el proceso del deslizamiento de Xinmo fue estudiado comparativamente con el programa DAN-W, que analiza dinámicas de deslizamiento, y múltiples modelos reológicos. Los resultados del estudio indican que el modelo friccional simuló favorablemente las características del movimiento en varias fases del deslizamiento de Xinmo. Este movimiento duró por lo menos 120 segundos, y tuvo una velocidad máxima de movimiento de 74 m/s. Además, el modelo friccional y sus parámetros se pueden usar en estudios similares para investigar los efectos dinámicos de un movimiento de tierra en la parte alta de una montaña.

ABSTRACT A catastrophic landslide hit Mount Fugui, Diexi Township, Mao County, Sichuan Province, at 05:38:58 on June 24, 2017. This landslide buried Xinmo Village, caused 83 deaths, and resulted in enormous losses of life and property. The landslide mass cut out and slid from a high position, loaded continuously, and accumulated at the top of the slope body. Subsequently, the landslide mass was transformed into avalanche debris. This process was a typical chain disaster of avalanche debris triggered by a ridge-top landslide. The total volume, elevation difference, and horizontal distance of the landslide were 1637.6 χ 104 m3, 1200 m, and 2800 m. In this research, the disaster-formation mechanism of the Xinmo Landslide was identified based on a geological field survey and remote sensing satellites. The disaster characteristics of the landslide source zone, debris avalanche zone, and accumulation zone were then numerically simulated. The entire process of the Xinmo Landslide movement was comparatively studied using DAN-W, a dynamic landslide software program, and multiple rheological models. The research findings indicated that the frictional model favorably simulated the movement characteristics of various phases of the Xinmo Landslide. This landslide lasted approximately 120 s, and it had a maximum velocity of movement of 74 m/s. Therefore, the frictional model and its parameters can be used in similar studies to investigate the dynamic disaster effects of ridge-top rock landslides.

Abstract: Background: To study the effective therapeutic concentration, drug application duration, irradiation duration and irradiation dosage of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) for treating vitiligo and observe its clinical efficacy. Objective: To assess the clinical efficacy of ALA-PDT for treating vitiligo. Methods: ALA with different drug concentrations, drug application durations, irradiation durations and irradiation dosages were adopted to treat skin lesions caused by vitiligo to determine the effective drug concentration, drug application duration, irradiation duration and irradiation dosage for treating three vitiligo volunteers and observe the therapeutic results. Results: The clinical trial suggested that ALA at a drug concentration of 1.5%, drug application duration for 3 hours, irradiation dosage of 80mw/cm2 and irradiation duration for 20 min was effective in treating vitiligo. Under these parameters, ALA-PDT was effective to the three vitiligo volunteers, with mild pain and feeling of burning but no other adverse reaction during treatment. Study limitations: Due to the small sample size in this study for the effectiveness of PDT in treating vitiligo and the potential variations in the efficacy for treating the disease at different areas, further studies shall be conducted for confirmation. Conclusions: ALA with a drug concentration at 1.5%, drug application duration for 3 hours, irradiation dosage of 80 mw/cm2 and irradiation duration for 20 min is effective in treating vitiligo. Therefore, ALA-PDT is safe and effective in treating the disease, with minor adverse events, providing a new method for treating vitiligo in the future.

Abstract: Background: In this study, cases with suspected urethral condylomata acuminata were examined by dermoscopy, in order to explore an effective method for clinical. Objective: To study the application of dermoscopy image analysis technique in clinical diagnosis of urethral condylomata acuminata. Methods: A total of 220 suspected urethral condylomata acuminata were clinically diagnosed first with the naked eyes, and then by using dermoscopy image analysis technique. Afterwards, a comparative analysis was made for the two diagnostic methods. Results: Among the 220 suspected urethral condylomata acuminata, there was a higher positive rate by dermoscopy examination than visual observation. Study limitations: Dermoscopy examination technique is still restricted by its inapplicability in deep urethral orifice and skin wrinkles, and concordance between different clinicians may also vary. Conclusion: Dermoscopy image analysis technique features a high sensitivity, quick and accurate diagnosis and is non-invasive, and we recommend its use.

Abstract: Port-wine stain is a type of common congenital superficial telangiectasia in the dermal layer mostly occurring on the forehead, face, and neck. The affected skin shows abnormal red or purple lesions, which darken and thicken. Nodular changes may develop with advancing age. If untreated, port-wine stains scarcely regress, which can have serious lifelong psychological impact on patients and affect their quality of life. In this report, we focused on two cases of port-wine stain in pediatric patients; the youngest patient was only 1.5 years old. During and after treatment, Hemoporfin-mediated photodynamic therapy features fewer adverse reactions, short light protection period, easy nursing, and good efficacy.