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Abstract Diabetes mellitus (DM) is a major cause of chronic kidney disease (CKD) and changes in lipoprotein. Literature data suggest that cholesterol associated with high-density lipoprotein (HDLc) plays a protective role against albuminuria and diabetic nephropathy. These factors are related with changes in serum apolipoproteins such Apo A-I. This work aims to evaluate the correlation of apolipoprotein A-I with renal function in diabetic outpatients. Samples were collected from 281 outpatients for analyses of glycated hemoglobin (HbA1c), serum creatinine (SCr), urea (BUN), cholesterol (TC), triglycerides (TG), HDL-cholesterol (HDLc) and estimation of glomerular filtration rate (eGFR). Urinary samples were obtained to assess urine albumin creatinine ratio (UACR). Triglyceride-glucose index (TyG) was calculated to estimate insulin resistance. The mean age was 61,5 ± 16,4 years. Most patients were female, Afro-Mestizo and over 50 years of age. Pearson's revealed negative correlation of creatinine with HDLc and Apo A-I. There was a correlation of eGFR with HbA1c, TG and HDLc. TyG presented a negative correlation with Apo A-I and HDLc. The highest quartiles of UACR presented the highest TyG and the lowest Apo A-I. In conclusion, Apo A-I indicated an association with insulin resistance and changes in renal function parameters, especially as a factor associated with the onset of albuminuria, with a better predictive potential than the HDLc.

https://doi.org/10.1590/1678-4324-2024230487

Cana-de-Açúcar e Café na Região Extremo Sul da Bahia, Brasil: Uma Análise Espaço-Temporal e dos Fatores Socioeconômicos
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Almeida, Regiane de Oliveira

; Cruz, Thyane Viana da

; Crepaldi, Maria Otávia

; Silva, Leonardo Thompson da

; Sousa, Ana Cristina de

; Cerqueira, Everton Mateus dos Santos

; Sena, Anderson

Sociedade & Natureza

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2023, Volume 35 elocation e66851

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The região extremo sul da Bahia (RESB - Extreme Southern Region of Bahia) has agricultural aptitude for several crops and has already been subjected to the expansion of sugarcane and coffee. Thus, this work analyzes the spatial and temporal dynamics of sugarcane and coffee monocultures in the RESB and their relationship with socioeconomic indices. The methodology consists of collection and analysis of data from the Instituto Brasileiro de Geografia e Estatística (IBGE), which is the main provider of geographic information and statistics in Brazil, the Companhia Nacional de Abastecimento (CONAB), which is responsible for providing technical information to support decision-making regarding the elaboration of policies aimed at agriculture and the Atlas Brasil platform. Data were collected regarding the planted area and the amount of sugarcane and coffee produced in the region between 1988 and 2019. To understand the relationship between expansion and socioeconomic factors, data related to gross domestic product (GDP) and municipal human development index (MHDI) were collected. This study identified the main sugarcane-producing municipalities (Caravelas, Mucuri, Medeiros Neto, Nova Viçosa, Lajedão, Ibirapuã and Santa Cruz Cabrália) and coffee (Prado, Itamaraju, Porto Seguro, Eunapolis, Teixeira de Freitas and Itabela). The expansion of these crops presents economic importance for the region, but presents a little contribution to the improvement of the various factors that make up the MHDI of the municipalities. This study concluded that the expansion of these crops changed the agricultural matrix of the region due to its specialization in the production of these crops to the detriment of others such as cocoa, for example.

Resumo A Região Extremo Sul da Bahia (RESB) possui aptidão agrícola para diversas culturas e já foi sujeita à expansão da cana-de-açúcar e do café. Assim, esse trabalho analisa a dinâmica espacial e temporal das monoculturas da cana-de-açúcar e do café na RESB e sua relação com índices socioeconômicos. A metodologia consiste em coleta e análise dos dados junto ao Instituto Brasileiro de Geografia e Estatística (IBGE), que é o principal provedor de informações geográficas e estatísticas do Brasil, a Companhia Nacional de Abastecimento (CONAB), que é responsável por fornecer informações técnicas para apoiar a tomada de decisão sobre a elaboração de políticas voltadas para a agricultura, e a Plataforma Atlas Brasil. Foram coletados dados sobre a área plantada e a quantidade produzida de cana-de-açúcar e de café na região entre os anos 1988 e 2019. Para compreender a relação entre a expansão e os fatores socioeconômicos, foram levantados dados referentes ao Produto Interno Bruto (PIB) e Índice de Desenvolvimento Humano Municipal (IDHM). Este trabalho identificou os principais municípios produtores de cana-de-açúcar (Caravelas, Mucuri, Medeiros Neto, Nova Viçosa, Lajedão, Ibirapuã e Santa Cruz Cabrália) e de café (Prado, Itamaraju, Porto Seguro, Eunápolis, Teixeira de Freitas e Itabela), e a expansão desses cultivos apresenta importância econômica para a região, porém apresenta pouca contribuição para a melhoria dos diversos fatores que compõem o IDHM dos municípios. Esse estudo concluiu que a expansão desses cultivos alterou a matriz agrícola da região devido a sua especialização na produção desses cultivos em detrimento de outros como o cacau, por exemplo.

https://doi.org/10.14393/sn-v35-2023-66851

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Abstract: En | Text: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

Association of serum lipoproteins and inflammatory parameters derived from the blood test with renal function in COVID-19 outpatients
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Viana, Glautemberg de Almeida

; Costa, Mac Dionys Rodrigues da

; Silva, Mateus Edson da

; Silva, Victória da Costa

; Ali, Arif

; Siqueira, Erlânia Alves de

; Alves, Renata de Sousa

; Martins, Alice Maria Costa

; Menezes, Ramon Róseo Paula Pessoa Bezerra de

; Queiroz, Maria Goretti Rodrigues de

; Sampaio, Tiago Lima

Brazilian Journal of Pharmaceutical Sciences

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2023, Volume 59 elocation e23293

Abstract: En | Text: En | PDF: En

Abstract Changes in lipoprotein metabolism are among the main causes of hemodynamic impairment in renal function. COVID-19 is an multisystemic inflammatory disease, aggravating this situation. This cross-sectional study investigated the relationship of serum lipoprotein profile with inflammatory parameters and renal function in 95 COVID-19 outpatients in comparison with 173 with flu-like symptoms. Serum samples were collected for the determination of total cholesterol and fractions, apolipoproteins (Apo A-I and Apo B), urea (sUr) and creatinine (sCr). The glomerular filtration rate (eGFR) was calculated. Neutrophil/lymphocyte (NLR) and platelet/lymphocyte (PLR) ratios were calculated as inflammatory parameters derived from the blood tests. COVID-19 patients presented lower high-density lipoprotein cholesterol (HDL-c) (47.90 ± 1.543 vs. 51.40 ± 0.992) and higher PLR (190.9 ± 9.410 vs. 137.6 ± 5.534) and NLR (3.40 ± 0.22 vs. 2.80 ± 0.15). Both NLR and PLR correlated with each other (r = 0.639). Furthermore, the Apo B/Apo A-I ratio was correlated with PLR (r = 0.5818) and eGFR (r = -0.2630). COVID-19 patients classified as at high risk of developing acute myocardial infarction based on the Apo B/ Apo A-I ratio had higher values for sUr/sCr. Thus, serum apolipoproteins, PLR, and NLR could be related to renal dysfunction in COVID-19.

https://doi.org/10.1590/s2175-97902023e23293

Telehealth for Parkinson disease patients during the COVID-19 pandemic: the TeleParkinson study
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Lima, Danielle Pessoa

; Gomes, Vlademir Carneiro

; Viana Júnior, Antonio Brazil

; Assis, Francisco Mateus Carvalho de

; Oliveira, Pedro Henrique Avelino

; Cunha, Letícia Chaves Vieira

; Braga, Isabelly Cavalcante

; Marques, Miriam Lindsay Silva

; Assunção, Jézica de Sousa

; Damasceno, Adeline Louise Lopes

; Barbosa, Ana Lara Guerra

; Moreira, Arthur Holanda

; Rocha, Maria Eduarda Quidute Arrais

; Porto, Maria Eduarda Mendes Pontes

; Chaves, Érica Carneiro Barbosa

; Oliveira, Liliane Maria de

; Roriz Filho, Jarbas de Sá

; Sobreira Neto, Manoel Alves

; Braga Neto, Pedro

Arquivos de Neuro-Psiquiatria

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oct 2022, Volume 80 N. 10 Pages 1026 - 1035

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Telemedicine allows Parkinson disease (PD) patients to overcome physical barriers to access health care services and increases accessibility for people with mobility impairments. Objective To investigate the feasibility indicators of a telehealth intervention for PD patients, including patient recruitment, attendance, technical issues, satisfaction, and benefits on levels of physical activity and sleep. Methods We conducted a single-center, single-arm study of telehealth video consultations using WhatsApp (Meta Platforms, Inc., Menlo Park, CA, USA). Also, we collected the feasibility indicators as the primary endpoints. All the patients in the study were previously evaluated in person by the same team. Results Patient recruitment, attendance, and technical issues rates were 61.3%, 90.5%, and 13.3%, respectively, with good scores of patient acceptance and satisfaction with the study intervention. The telehealth intervention improved physical activity, including the number of walks for at least 10 continuous minutes (p = 0.009) and the number of moderate-intensity activities lasting at least 10 continuous minutes (p = 0.001). The Pittsburgh sleep quality index (PSQI) scores also improved for one of its components: perceived sleep duration (p < 0.001) and for total Pittsburgh score (p < 0,001). The average travel time saving was 289.6 minutes, and money-saving was R$106.67 (around USD 18; almost 10% of the current minimum wage in Brazil). Conclusions Direct-to-patient telehealth video consultations proved to be feasible and effective and had a positive impact on physical activity levels and sleep in PD patients.

Resumo Antecedentes A telemedicina permite que pacientes com doença de Parkinson (DP) superem barreiras físicas para acessar serviços de saúde e aumenta a acessibilidade para pessoas com mobilidade reduzida. Objetivo Investigar indicadores de viabilidade de uma intervenção em telessaúde para pacientes com DP, incluindo recrutamento, atendimento, aderência, problemas técnicos, satisfação e benefícios nos níveis de atividade física e sono. Métodos Foi conduzido um estudo de centro e braço únicos baseado em consultas por telessaúde com utilização do WhatsApp (Meta Platforms, Inc., Menlo Park, CA, EUA). Foram calculados indicadores de viabilidade como desfechos primários. Resultados As taxas de recrutamento, atendimento e problemas técnicos foram 61,3%, 90,5% e 13,3%, respectivamente, com bons escores de aceitação e satisfação com a intervenção. A intervenção melhorou os níveis de atividade física, incluindo o número de passos por pelo menos 10 minutos contínuos (p = 0,009) e o número de atividades intensas e moderadas com duração de pelo menos 10 minutos contínuos (p = 0,001). O Índice de Qualidade do Sono de Pittsburgh melhorou nos seguintes componentes: duração percebida do sono (p < 0,001) e escore total (p < 0,001). A média do tempo de viagem médio poupado foi de 289,6 minutos, e a economia financeira foi de R$ 106,67 reais (por volta de USD 18; quase 10% do salário mínimo atual do Brasil). Conclusões As consultas por vídeo provaram ser viáveis e efetivas, com impacto positivo nos níveis de atividade física e sono de pacientes com DP.

https://doi.org/10.1055/s-0042-1758751

Hypertriglyceridemia promotes dysfunctions in high-density lipoprotein increasing the cardiovascular risk
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Meneses, Richard Rarison Cavalcante

; Damasceno, Nágila Raquel Teixeira

; Cartolano, Flávia De Conti

; Verde, Sara Maria Moreira Lima

; Lira, Letícia Gomes

; Dantas, Mariana Brito

; Viana, Glautemberg de Almeida

; Silva, Mateus Edson da

; Sousa, Ederson Laurindo Holanda de

; Meneses, Gdayllon Cavalcante

; Ferreira, Jamile Magalhães

; Sampaio, Tiago Lima

; Queiroz, Maria Goretti Rodrigues de

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e20488

Abstract: En | Text: En | PDF: En

Abstract Hypertriglyceridemia is associated with several metabolic diseases. The triglycerides (TG) disrupt the cholesterol reverse transport and contribute to increased levels of low-density lipoprotein (LDL). High-density lipoprotein (HDL) acts in cholesterol reverse transport as an anti-inflammatory and antioxidant. This study aims to investigate the role of hypertriglyceridemia in the functionality of HDL. Individuals were divided into 4 groups based on high or low HDL-c and triglycerides levels. Biochemical and anthropometric analysis were performed. This study demonstrated that triglycerides promote dysfunctions on HDL, increasing the cardiovascular risk. Blood pressure was higher in subjects with low HDL. Women presented higher levels of HDL-c and low percentage of fat mass. The highest levels of triglycerides were observed in older age. In addition, high levels of triglycerides were associated with higher total cholesterol and LDL-c levels, non-HDL-c, non-esterified fatty acids, and blood glucose, increasing in the ratio of non-HDL-c/HDL-c and ApoB/ApoA-I. The increase of triglycerides levels progressively impairs the antioxidant capacity of HDL, probably due to a higher occurrence of fatty acid peroxidation in individuals with hypertriglyceridemia. Patients with high HDL and low TG levels increased the Lag Time. Furthermore, a positive correlation was found between TG versus HDL particle size, variables that depend on age and anthropometric parameters.

https://doi.org/10.1590/s2175-97902022e20488

Back to The Future: How To Define Prognosis in MINOCA?
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Ritt, Luiz Eduardo Fonteles

; Viana, Mateus dos Santos

International Journal of Cardiovascular Sciences

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nov 2021, Volume 34 N. 5 Pages 10 - 11

Abstract: En | Text: En | PDF: En

https://doi.org/10.36660/ijcs.20210229 8 downloads

Uso de álcool, conflitos familiares e supervisão parental entre estudantes do ensino médio
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Neves, João Victor Viana da Silva

; Carvalho, Lucas Almeida de

; Carvalho, Mateus Almeida de

; Silva, Érica Thaís Costa

; Alves, Maria Luiza Terra Santos

; Silveira, Marise Fagundes

; Silva, Rosângela Ramos Veloso

; Almeida, Maria Tereza Carvalho

Ciência & Saúde Coletiva

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oct 2021, Volume 26 N. 10 Pages 4761 - 4768

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Investigou-se a associação entre o consumo de álcool pelos escolares com os conflitos familiares, supervisão dos pais e qualidade dos relacionamentos. Estudo transversal realizado com 1.265 adolescentes de 21 escolas. Foi utilizada a versão brasileira do Inventário de Triagem do Uso de Drogas/DUSI e estimadas prevalências absolutas e relativas para variáveis categóricas, e conduzidas análises bivariadas: teste Qui Quadrado de Pearson. Para magnitude da associação entre a variável dependente e independentes foram estimadas razões de prevalências por meio deregressão multivariável de Poisson. Houve associação do consumo de álcool com uso de drogas por familiares, discussões frequentes e desconhecimento dos pais sobre o que os adolescentes fazem. Supervisão familiar, bom relacionamento com pais/responsáveis, estabelecimento de vínculo familiar afetivo e ciência dos pais acerca do que os adolescentes fazem e onde estão, foram fatores de proteção para uso de álcool. Concluiu-se que a alta taxa de escolares que consomem álcool é preocupante, passível de complicações da saúde na sua integralidade, sendo fundamental relação familiar harmonizada. A implementação de práticas interventivas entre escola e Estratégia de Saúde da Família, podem contribuir no estabelecimento de vínculo protetivo.

Abstract The association between alcohol consumption by students with family conflicts, parental supervision and quality of relationships was investigated. A cross-sectional study was conducted with 1,265 adolescents from 21 schools. The Brazilian version of the Drug Use Screening Inventory/DUSI was used, and absolute and relative prevalence for categorical variables was estimated, while bivariate analyses and Pearson’s Chi Square test were conducted. For the magnitude of the association between the dependent and independent variables, prevalence ratios were estimated using Poisson multivariate regression. There was an association between alcohol consumption and drug use by family members, frequent discussions and parental lack of awareness about adolescents’ activities. Family supervision, a good relationship with parents/guardians, establishing an affective family bond and parents’ knowledge about teenagers’ whereabouts, were protective factors for alcohol use. The conclusion was that the high rate of schoolchildren who consume alcohol is worrying, liable to health complications in general, and a harmonized family relationship is fundamental. The implementation of measures of intervention between school and the Family Health Strategy, can contribute to the establishment of a protective bond.

https://doi.org/10.1590/1413-812320212610.22392020 118 downloads

Uso de álcool, conflitos familiares e supervisão parental entre estudantes do ensino médio
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Neves, João Victor Viana da Silva

; Carvalho, Lucas Almeida de

; Carvalho, Mateus Almeida de

; Silva, Érica Thaís Costa

; Alves, Maria Luiza Terra Santos

; Silveira, Marise Fagundes

; Silva, Rosângela Ramos Veloso

; Almeida, Maria Tereza Carvalho

Ciência & Saúde Coletiva

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2021, Volume 26 N. 10 Pages 4761 - 4768

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-812320212610.22392020

10.

Periphyton use on microbial dynamics, water quality, and Nile tilapia growth in rearing tanks
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Silva, Jéssica Lucinda Saldanha da

; Carvalho, Fátima Cristiane Teles de

; Carvalho, Rubson Mateus Matos

; Sousa, Oscarina Viana de

Pesquisa Agropecuária Brasileira

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2021, Volume 56 elocation e01520

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: O objetivo deste trabalho foi avaliar o efeito do uso de substrato artificial para o crescimento de biofilme perifítico sobre a composição microbiológica do biofilme, a qualidade da água e o desempenho zootécnico de tilápia-do-nilo (Oreochromis niloticus), em tanques de cultivo. O experimento consistiu de dois tratamentos: presença e ausência de substrato artificial para o crescimento de perifíton, com cinco repetições. Os parâmetros de qualidade de água foram avaliados durante todo o período experimental. A cada duas semanas, foram coletadas amostras do perifíton para análise da sua composição microbiológica e realizadas medidas biométricas dos peixes. A quantidade de bactérias heterotróficas no biofilme aumentou durante o período experimental, mas a de Aeromonas reduziu com o uso do substrato artificial. O nitrogênio amoniacal total dos tanques com perifíton reduziu 30% em relação ao do controle. As tilápias criadas com o biofilme apresentaram peso final 2,4 vezes maior que às submetidas ao controle, além de aumento de 59,19% na sua produtividade. O uso de substrato artificial para a formação de biofilme perifítico em cultivo de tilápia em tanques favorece a manutenção da qualidade da água de cultivo, a proteção dos peixes contra patógenos e a melhora do desempenho zootécnico dos peixes.

Abstract: The objective of this work was to evaluate the effect of the use of an artificial substrate for periphytic biofilm growth on the microbiological composition of the biofilm, water quality, and zootechnical performance of Nile tilapia (Oreochromis niloticus) in rearing tanks. The experiment consisted of two treatments: presence and absence of artificial substrate for the growth of periphyton, with five replicates. Water quality parameters were evaluated throughout the entire experimental period. Every two weeks, samples of the periphyton were collected for the analysis of its microbiological composition and biometric measurements of the fish were performed. The number of heterotrophic bacteria in the biofilm increased during the experimental period, but that of Aeromonas decreased with the use of the artificial substrate. The total ammonia nitrogen in the tanks with periphyton reduced in 30% compared with that of the control. Tilapia reared with the biofilm showed a final weight 2.4 times greater than that of those subjected to the control, as well as an increase of 59.19% in their productivity. The use of an artificial substrate for periphytic biofilm in Nile tilapia rearing tanks favors the maintenance of the quality of the culture water, the protection of the fish against pathogens, and the improvement of the zootechnical performance of the fish.

https://doi.org/10.1590/s1678-3921.pab2021.v56.01520 61 downloads

11.

Competência Prognóstica Distinta entre Modelo Clínico e Anatômico em Síndromes Coronarianas Agudas: Comparação por Tipo de Desfecho
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Viana, Mateus S.

; Correia, Vitor C. A.

; Ferreira, Felipe M.

; Lacerda, Yasmin F.

; Bagano, Gabriela O.

; Fonseca, Leticia L.

; Kertzman, Lara Q.

; Melo, Milton V.

; Noya-Rabelo, Marcia M.

; Correia, Luis C L

Arquivos Brasileiros de Cardiologia

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aug 2020, Volume 115 N. 2 Pages 219 - 225

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento Eventos isquêmicos recorrentes decorrem de instabilidade de placa aterosclerótica, enquanto morte após um evento isquêmico decorre da gravidade do insulto. A natureza diversa desses tipos de eventos pode fazer com que dados clínicos e anatômicos tenham diferentes capacidades prognósticas a depender do tipo de desfecho. Objetivo Identificar as predileções prognósticas de dados clínicos e dados anatômicos em relação a desfechos coronários fatais e não fatais durante hospitalização de pacientes com síndromes coronarianas agudas (SCA). Métodos Pacientes consecutivamente admitidos por SCA que realizaram coronariografia foram recrutados. O escore SYNTAX foi utilizado como modelo anatômico e o escore GRACE como modelo clínico. A capacidade preditora desses escores foi comparada quando à predição de desfechos isquêmicos não fatais (infarto ou angina refratária) e de morte cardiovascular durante hospitalização. Significância estatística foi definida por p < 0,05. Resultados Entre 365 indivíduos, 4,4% foi a incidência de óbito hospitalar e 11% de desfechos isquêmicos não fatais. Para morte cardiovascular, ambos os escores — SYNTAX e GRACE — apresentaram capacidade discriminatória, com estatísticas-C similares: 0,80 (95%IC: 0,70–0,92) e 0,89 (95%IC 0,81–0,96), respectivamente — p=0,19. Quantos aos desfechos isquêmicos não fatais, o escore SYNTAX apresentou valor preditor (estatística-C = 0,64; 95%IC 0,55–0,73), porém o escore GRACE não mostrou associação com esse tipo de desfecho (estatística-C = 0,50; 95%IC: 0,40–0,61) — p=0,027. Conclusão Os modelos clínico e anatômico predizem satisfatoriamente morte cardiovascular em SCA, enquanto a recorrência de instabilidade coronária é melhor prevista por características anatômicas do que por dados clínicos. (Arq Bras Cardiol. 2020; 115(2):219-225)

Abstract Background Recurrent ischemic events are mediated by atherosclerotic plaque instability, whereas death after an ischemic event results from gravity of insult and ability of the organism to adapt. The distinct nature of those types of events may respond for different prediction properties of clinical and anatomical information regarding type of outcome. Objective To identify prognostic properties of clinical and anatomical data in respect of fatal and non-fatal outcomes of patients hospitalized with acute coronary syndromes (ACS). Methods Patients consecutively admitted with ACS who underwent coronary angiography were recruited. The SYNTAX score was utilized as an anatomic model and the GRACE score as a clinical model. The predictive capacity of those scores was separately evaluated for prediction of non-fatal ischemic outcomes (infarction and refractory angina) and cardiovascular death during hospitalization. It was considered as significant a p-value <0,05. Results EAmong 365 people, cardiovascular death was observed in 4,4% and incidence of non-fatal ischemic outcomes in 11%. For cardiovascular death, SYNTAX and GRACE score presented similar C-statistic of 0,80 (95% IC: 0,70 – 0,92) and 0,89 (95% IC 0,81 – 0,96), respectively – p = 0,19. As for non-fatal ischemic outcomes, the SYNTAX score presented a moderate predictive value (C-statistic = 0,64; 95%IC 0,55 – 0,73), whereas the GRACE score did not presented association with this type of outcome (C-statistic = 0,50; 95%IC 0,40-0,61) – p = 0,027. Conclusion Clinical and anatomic models similarly predict cardiovascular death in ACS. However, recurrence of coronary instability is better predicted by anatomic variables than clinical data. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)

https://doi.org/10.36660/abc.20190062 830 downloads

12.

COVID-19 e Eventos Coronários Agudos – Danos Colaterais. Um Relato de Caso
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Ritt, Luiz Eduardo Fonteles

; Viana, Mateus S.

; Feitosa, Gustavo Freitas

; Oliveira, Adriano Martins de

; Souza, Fabio Solano

; Darzé, Eduardo Sahade

Arquivos Brasileiros de Cardiologia

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jun 2020, Volume 114 N. 6 Pages 1072 - 1075

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20200329 1944 downloads

13.

Fatores associados à qualidade de vida dos idosos octogenários da zona rural de Uberaba/MG
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Buso, Ana Luisa Zanardo

; Viana, Dayane Aparecida

; Alves, Lilane Maria da Silva

; Dias, Flávia Aparecida

; Oliveira, Daniel Vicentini de

; Antunes, Mateus Dias

; Rodrigues, Leiner Resende

; Tavares, Darlene Mara dos Santos

Cadernos Saúde Coletiva

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jun 2020, Volume 28 N. 2 Pages 231 - 240

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução A longevidade pode ser acompanhada de diversos fatores que interferem negativamente na qualidade de vida (QV) dos idosos e torna-se necessário investigar quais são estes fatores na zona rural. Objetivo Identificar os fatores associados à QV de idosos octogenários da zona rural de Uberaba-MG. Método Estudo transversal com 74 idosos octogenários residentes na zona rural que foram avaliados quanto ao perfil sociodemográfico, número de morbidades, qualidade de vida e funcionalidade. A análise dos dados foi conduzida por meio dos testes t-Student, correlação de Pearson e a Regressão linear múltipla (p < 0,05). Resultados No domínio físico da QV, os menores escores relacionaram-se ao maior número de morbidades e de incapacidade funcional nas atividades instrumentais de vida diária. Conclusão Os menores escores de QV em idosos octogenários da zona rural de Uberaba-MG estão associados ao maior número de morbidades e de incapacidade funcional.

Abstract Background The longevity can be followed by several factors that interfere negatively in the life quality (LQ) of the elderly, for this reason it is necessary to investigate which are these factors in the rural area. Objective To identify the factors associated with QoL of octogenarian elderly in the rural area of Uberaba-MG. Method A cross-sectional study with 74 octogenarian elderly living in the rural area was carried out. The sociodemographic profile, number of morbidities, quality of life and functionality were evaluated. Data analysis was performed using Student's t-tests, Pearson's correlation and Multiple linear regression (p <0.05). Results In the physical domain of LQ, the lowest scores were related to the greater number of morbidities and functional inability in the instrumental activities of daily living. Conclusion The lower LQ scores in the octogenarian elderly in the rural area of Uberaba-MG are associated with greater morbidity and functional disability.

https://doi.org/10.1590/1414-462x202000020193 922 downloads

14.

Option for the Radial versus Femoral Access in Coronary Intervention in Acute Coronary Syndromes: A Risk-Treatment Paradox
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Lacerda, Yasmin Falcon

; Sá, Nicole Cruz de

; Suerdieck, Jessica Gonzalez

; Fonseca, Letícia

; Lopes, Fernanda

; Sodré, Gabriella Sant'Ana

; Viana, Mateus dos Santos

; Rabelo, Marcia Maria Noya

; Correia, Luis Claudio Lemos

International Journal of Cardiovascular Sciences

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dec 2018, Volume 31 N. 6 Pages 562 - 568

Abstract: En | Text: En | PDF: En

Abstract Background: In coronary procedures, although the radial approach protects patients from hemorrhagic complications, it is technically more complex than the femoral approach. Objectives: To test the hypothesis that the radial approach is the procedure of choice in ACS patients due to the high risk of bleeding; and to identify independent predictors of the choice for radial access. Methods: Patients admitted for ACS who underwent invasive coronary procedure were included. We registered the type of access (femoral or radial) chosen by the physician for the first angiography; the investigators did not interfere with this choosing process. Student’s t-test was used for comparisons between the CRUSADE and ACUITY scores. Predictors of radial access were compared between the groups. Statistical significance was defined by p < 0,05. Results: Radial access was chosen in 67% of 347 consecutive patients. Patients who underwent radial approach had lower risk of bleeding determined by CRUSADE (30 ± 14 vs. 37 ± 15; p < 0.001) as compared with femoral access. In multivariate analysis, four variables were identified as independent predictors negatively associated with radial access - age (OR = 0.98; 95%CI = 0.96 - 0.99), creatinine (OR = 0.54; 95%CI = 0.3 - 0.98), signs of left ventricular failure (OR = 0.45; 95% CI = 0.22 - 0.92) and previous CABG (OR = 0.022; 95%CI = 0.003 - 0.166). Conclusion: The propensity to choose radial over femoral access in coronary intervention was not primarily influenced by patients’ bleeding risk. Predictors of this decision, identified in the study, indicated less complex patients, suggesting that the difficulty in performing the technique was a stronger determinant than its potential antihemorrhagic effect. (Int J Cardiovasc Sci. 2018; [online].ahead print, PP.0-0)

https://doi.org/10.5935/2359-4802.20180066 519 downloads

15.

Tecnologia educacional para mediar práticas educativas sobre alimentação complementar na Amazônia: estudo de validação
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Viana, Lujhon Rodrigues

; Barreto, Mateus Martins

; Girard, Claudia Cristina Pinto

; Teixeira, Elizabeth

RISTI - Revista Ibérica de Sistemas e Tecnologias de Informação

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sep 2018, N. 28 Pages 29 - 40

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O estudo teve como objetivo validar uma cartilha para mediar o ensino- aprendizagem de mães de crianças de seis a doze meses sobre a alimentação complementar. Pesquisa metodológica com abordagem mista, realizada na Universidade do Estado do Pará Campus XIII, no município de Tucuruí -PA. Foram participantes 13 juízes da área sócio humanística e da área da saúde. O instrumento de coleta de dados foi um questionário, aplicado no período de dezembro de 2016 a março de 2017. Para o cálculo do índice de validade de conteúdo foi utilizada a estatística descritiva comportamental e para a análise qualitativa a análise temática de convergência. A média dos escores dos itens analisados correspondeu a um IVC de 92%. O resultado apontou a adequação da tecnologia a também a necessidade de aprimoramento. Considerações finais: A tecnologia educacional foi considerada válida estatisticamente para ser usada pelos profissionais da saúde com o público-alvo.

The study aimed to validate a primer to mediate the teaching-learning of mothers of children from six to twelve months on complementary feeding. Methodological research with mixed approach, held at the University of Pará Campus XIII, in the municipality of Tucuruí -PA. Thirteen judges from the socio- humanistic and health area were participants. The data collection instrument was a questionnaire, applied in the period from December 2016 to March 2017. For the calculation of the index of content validity was used descriptive behavioral statistics and for the qualitative analysis the thematic analysis of convergence. The mean of the items analyzed corresponded to a CVI of 92%. The result pointed to the suitability of the technology as well as the need for improvement. Final considerations: Educational technology was considered statistically valid for use by health professionals with the target audience.

https://doi.org/10.17013/risti.28.29-40 1249 downloads

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