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RESUMEN Introducción: La Pandemia COVID-19, ha tenido impactos negativos en la salud física y mental de las personas, así como las medidas adoptadas por los gobiernos, para prevenir el contagio masivo de la población como el confinamiento, el aislamiento social, el trabajo y educación virtual. Dentro de los afectados por estos cambios, se encontrarían los estudiantes universitarios del área de la salud, que además de estudiar en estas condiciones de pandemia, no han podido hacer sus prácticas de los servicios de salud. Esta situación de exposición al aislamiento, podría afectar la salud mental de los jóvenes estudiantes universitarios. Objetivo: determinar los niveles de depresión, ansiedad y estrés en estudiantes universitarios y su relación con variables sociodemográficas y las características del aislamiento social durante la Pandemia COVID-19. Métodos: Se realizó un estudio descriptivo, observacional, de corte transversal y cuantitativo, con una muestra de 818 estudiantes universitarios de facultades de ciencias de la salud, mediante el cuestionario autoadministrado DASS-21. Resultados: Los principales hallazgos fueron: una mayor prevalencia en niveles altos (severos y extremadamente severos) en la ansiedad, alcanzado casi a 4 de cada 10 de los evaluados; por otro lado, en depresión y el estrés, 2 de cada 10 de los evaluados, se encontraron en los niveles mencionados. En relación con las variables sociodemográficas, las relacionadas con el COVID-19 y aislamiento social, se hallaron diferencias estadísticamente significativas con el género (mujeres > varones), el haber tenido COVID-19 (Sí > No) y vivir con familiares como antes de la pandemia (Sí > No) obtuvieron en promedio mayores puntajes en depresión, ansiedad y estrés. Conclusión: Los estudiantes que presentaron mayor depresión, ansiedad y estrés con una diferencia significativa fueron de género femenino, con antecedentes de haber tenido Covid-19, menor contacto con familiares y haber cumplido con aislamiento social total.

ABSTRACT Introduction: The COVID-19 Pandemic has had negative impacts on the physical and mental health of people, as well as the measures adopted by governments to prevent the massive contagion of the population, such as confinement, social isolation, virtual work, and virtual education. Among those affected by these changes would be university students in the health area who, in addition to studying in these pandemic conditions, have been unable to do their health service practices. This situation of exposure to isolation could affect the mental health of young university students. Objective: To determine the levels of depression, anxiety, and stress in university students, their relationship with sociodemographic variables, and the characteristics of social isolation during the COVID-19 Pandemic. Methods: A descriptive, observational, cross-sectional, and quantitative study was carried out with a sample of 818 university students from health sciences faculties using the DASS-21 self-administered questionnaire. Results: The main findings were a higher prevalence of high levels (severe and highly severe) in anxiety, reaching almost 4 out of 10 of those evaluated; On the other hand, in depression and stress, 2 out of 10 of those evaluated were found at the mentioned levels. Concerning the sociodemographic variables, those related to COVID-19 and social isolation, statistically significant differences were found with gender (women > men), having had COVID-19 (Yes > No), and living with relatives as before. On average, the pandemic (Yes > No) obtained higher scores in depression, anxiety, and stress. Conclusion: The students who presented greater depression, anxiety, and stress with a significant difference were female, with a history of having had Covid-19, less contact with family members, and having complied with total social isolation

https://doi.org/10.52379/mcs.v8i1.315

Third National Registry of Cardiac Rehabilitation Programs in Mexico (RENAPREC III-2022)
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Lara-Vargas, Jorge A.

; Ilarraza-Lomelí, Hermes

; García-Saldivia, Marianna

; Pineda-García, Alfredo D.

; Leyva-Valadez, Eduardo A.

; Justiniano-Cordero, Samuel

; Sahagún-Olmos, Roberto

; Zavala-Ramírez, Juana

; Cassaigne-Guasco, María E.

; Sánchez-Limón, Edgar-F

; Castañeda-López, Javier

; Cerón-Enríquez, Norma

; Ku-González, Andrés

; Arteaga-Martínez, Rodolfo

; Hinojosa-López, Tania

; Vergara-Guzmán, Jéssica

; Pérez-Vázquez, Daniel I.

; Gasca-Zamudio, Pedro D.

; Aranda-Ayala, Zulema L.

; Vacío-Reyes, Martha E.

; Reza-Orozco, Marco

; Alcocer-Gamboa, Miguel A.

; Hernández-González, Pedro A.

; Pérez-Reyes, Angélica A.

; Núñez-Urquiza, Juan P.

; Alonso-Sánchez, Jesús

; Franco-Valles, Sarahí

; Romo-Escamilla, Ricardo E.

; Nuriulú-Escobar, Patricia

; Serna-Santamaría, Iván

; Avilés-González, Jorge

; Salgado-Solorio, María C.

; Muñoz-Gutiérrez, Luz M.

; Mendoza-Díaz, Pedro M.

; Ávila-Estrada, Ángel

; Morales-Medina, Carlos

; Lara-Vázquez, Eduardo

; Rodríguez-Herrera, Paulina

; Galván-López, María

; Segoviano-Mendoza, Georgina

; De-la-Torre-Cruz, Fabiola

; Jiménez-Campos, Cecilia

; Ramírez-Meléndez, Alejandra

; Almaraz-Ríos, Alejandro

; González-Bonilla, Mezthly

; Rojano-Castillo, Jessica

; Rius-Suarez, María D.

Archivos de cardiología de México

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dec 2023, Volume 93 N. 4 Pages 405 - 416

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

resumen está disponible en el texto completo

Abstract Introduction: In Mexico, cardiac rehabilitation (CR) as an interdisciplinary intervention with therapeutic impact in patients with heart disease is growing. There is the need to know actual conditions of CR in our country. Objectives: The objective of this National Registry is to follow-up those existing and new CR units in Mexico through the comparison between the two previous registries, RENAPREC-2009 and RENAPREC II-2015 studies. This is a descriptive study focused on diverse CR activities such as assistance training, and certification of health professionals, barriers, reference, population attended, interdisciplinarity, permanence over time, growth prospects, regulations, post-pandemic condition, integrative characteristics, and scientific research. Results: Data were collected from 45 CR centers in the 32 states, 75.5% are private practice units, 67% are new, 33% were part of RENAPREC II-2015, and 17 have continued since 2009. With a better distribution of CR units along the territory, the median reference of candidates for CR programs is 9% with a significant reduction into tiempo of enrollment to Phase II admission (19 ± 11 days). Regarding to previous registries, the coverance of Phases I, II, and III is 71%, 100%, and 93%, respectively; and a coverance increases in evaluation, risk stratification, and prescription, more comprehensive attendance and prevention strategies. Conclusions: CR in Mexico has grown in the past 7 years. Even there is still low reference and heterogeneity in specific processes, there are strengths such as interdisciplinarity, scientific professionalization of specialists, national diversification, and an official society that are consolidated over time.

https://doi.org/10.24875/acm.22000235

Hypercalcemic crisis as a presentation of primary hyperparathyroidism
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Bedini, Iván

; Sylvestre Begnis, Gustavo

; Poenitz, Fernando

; Polillo, David C.

; Vargas, María Cecilia

; Bolzán, Diamela

; Ramírez Stieben, Luis A.

Medicina (Buenos Aires)

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dec 2023, Volume 83 N. 5 Pages 804 - 807

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Hyperparathyroidism-induced hypercalcemic crisis (HIHC) is an unusual state of marked progressive pri mary hyperparathyroidism (PHPT). Patients have severe hypercalcemia and may have severe symptoms such as kidney failure, acute pancreatitis, and mental changes. PHPT is due to the presence of a single gland adenoma/ disease in 80 to 85%; parathyroid carcinoma is reported in <1%. Among patients with adenoma, atypical parathy roid tumor can be found infrequently. Parathyroidectomy is the only curative approach for PHPT. In this report we present three cases of HIHC due to giant parathyroid adenomas (GPAs), one of them with histopathological characteristics of an atypical parathyroid tumor, with satisfactory evolution after parathyroidectomy.

Resumen La crisis hipercalcémica inducida por hiperparatiroi dismo (HIHC) es un estado inusual de hiperparatiroidis mo primario progresivo y marcado (HPTP). Los pacientes tienen hipercalcemia grave y pueden tener síntomas graves como insuficiencia renal, pancreatitis aguda y cambios mentales. El HPTP se debe a la presencia de un adenoma/enfermedad de una sola glándula en 80 a 85%; el carcinoma de paratiroides se informa en <1%. Entre los pacientes con adenoma, el tumor paratiroideo atípico se puede encontrar con baja frecuencia. La paratiroidec tomía es el único abordaje curativo del HPTP. En este reporte presentamos tres casos de HIHC por adenomas paratiroideos gigantes (APGs), uno de ellos con características histopatológicas de tumor paratiroideo atípico, con evolución satisfactoria luego de paratiroidectomía.

Carcinoma de cérvix abscedado por Schaalia turicensis
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Doldán, Leila

; Huarachi-Chirilla, Yaneth

; Vargas, Cristian

; Domínguez, Cecilia

; Chediack, Viviana

; Cunto, Eleonora

Medicina (Buenos Aires)

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jun 2023, Volume 83 N. 2 Pages 341 - 341

Abstract: Es | Text: Es | PDF: Es

Standards for psychosocial care in pediatric cancer: adapted proposal for Latin American and Caribbean countries
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Trigoso, Viviana

; Vásquez, Liliana

; Fuentes-Alabi, Soad

; Pascual, Claudia

; Méndez, Teresa

; Maradiegue, Essy

; Villegas, Mariela

; Perina, Elisa

; Ahumada, Eugenia

; de Bragança, João

; Zubieta, Marcela

; Jiménez, María del Pilar

; Bernedo, Hernan

; Ruda, Lourdes

; Sierralta, Melisa

; Motta, Alessandra

; Rossell, Nuria

; Vargas, Daniela

; Salazar, Yurfa

; López, Marisa

; Plascencia, Oscar

; Arita, Armando

; Molinas, Raquel

; Salaverria, Carmen

; Velásquez, Oscar

; Ugaz, Cecilia

Revista Panamericana de Salud Pública

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2023, Volume 47 elocation e156

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

resumen está disponible en el texto completo

ABSTRACT Objective. To highlight the objectives, achievements, challenges, and next steps for the World Health Organization’s Global Initiative for Childhood Cancer (GICC) framework, a project designed to improve psychosocial care (PSC) in pediatric cancer centers across Latin America and the Caribbean (LAC). Methods. The project was launched in Peru, the first GICC focal country, in November 2020. The diagnosis phase included a survey and a semistructured interview with health professionals to assess PSC practices in institutions, and a needs assessment survey for caregivers. In the second phase, a strategic plan was developed to address the identified needs, including the adaptation of PSC standards, the establishment of multicenter working groups, the expansion of the proposal, and the development of materials. Results. The study found that PSC was not being adequately provided in accordance with international standards. Six adapted standards were proposed and validated, and more than 50 regional health professionals participated in online activities to support the project. The implementation process is currently ongoing, with the establishment of five multidisciplinary working groups, one regional committee, and the production of 16 technical outputs. Conclusion. This project represents a substantial step forward to improve PSC for pediatric patients with cancer and their families in LAC countries. The establishment of working groups and evidence-based interventions strengthen the proposal and its implementation. Development of health policies that include PSC according to standards is needed to achieve sustainable results in the quality of life of children with cancer and their families.

RESUMO Objetivo. Destacar os objetivos, as conquistas, os desafios e as próximas etapas da Iniciativa Global para o Câncer Infantil (GICC), um projeto criado pela Organização Mundial da Saúde para melhorar a atenção psicossocial em centros de câncer pediátrico na América Latina e no Caribe. Métodos. O projeto foi lançado no Peru, o primeiro país focal da GICC, em novembro de 2020. A fase de diagnóstico incluiu uma pesquisa e uma entrevista semiestruturada com profissionais de saúde para avaliar as práticas de atenção psicossocial nas instituições, bem como uma pesquisa para avaliar as necessidades dos cuidadores. Na segunda fase, foi desenvolvido um plano estratégico para atender às necessidades identificadas, incluindo uma adaptação de padrões de atenção psicossocial, o estabelecimento de grupos de trabalho multicêntricos, a expansão da proposta e o desenvolvimento de materiais. Resultados. O estudo constatou que, de acordo com padrões internacionais, a atenção psicossocial não estava sendo adequadamente oferecida. Seis padrões adaptados foram propostos e validados, e mais de 50 profissionais de saúde da região participaram de atividades on-line para apoiar o projeto. O processo de implementação está em andamento, com a formação de cinco grupos de trabalho multidisciplinares e um comitê regional e a produção de 16 relatórios técnicos. Conclusão. Este projeto representa um avanço substancial para melhorar a atenção psicossocial para pacientes pediátricos com câncer e suas famílias nos países da América Latina e do Caribe. A criação de grupos de trabalho e intervenções baseadas em evidências fortalecem a proposta e sua implementação. É preciso desenvolver políticas de saúde que incluam atenção psicossocial segundo padrões estabelecidos para alcançar resultados sustentáveis na qualidade de vida das crianças com câncer e de suas famílias.

https://doi.org/10.26633/rpsp.2023.156

Factors associated with perception of the current silhouette and body image dissatisfaction in adults with obesity
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Streb, Anne Ribeiro

; Vieira, Carolina Graef

; Silva, Caroline Soares da

; Bertuol, Cecília

; Vargas, Patrine

; Del Duca, Giovani Firpo

Revista de Nutrição

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2023, Volume 36 elocation e220116

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective To verify the factors associated with the perception of current silhouette and body image dissatisfaction in adults with obesity. Methods Cross-sectional study derived from the baseline of a randomized clinical trial. The perception of current silhouette and dissatisfaction with body image, defined by the difference between the perception of current and ideal silhouette, were obtained from a scale that ranged from one (smallest silhouette) to nine (largest silhouette). The independent variables investigated as associated factors (crude and adjusted linear regression) were: sex, age, skin color, body mass index (kg/m2), percentage of body fat, level of physical activity, and food intake. Results Sixty-nine obese individuals (body mass index ≥30kg/m2) were studied, 42 of whom were female and with the following mean values: 34.7 (±7.2) years; 33.5 (±2.8) kg/m2, and current silhouette of 6.6 (±0.9). All were dissatisfied with their excess body weight. The categories associated with a perception that matched the current silhouettes were male sex, white skin color, and higher body mass index values when compared to female sex, non-white, and lower body mass index values, respectively. Regarding body image dissatisfaction, white people had lower scores than those with other skin colors. Conclusion Being male, having white skin color, and having a higher body mass index were risk factors for the perception of larger body silhouettes, while only non-white skin color was associated with dissatisfaction with body image.

RESUMO Objetivo Verificar os fatores associados à percepção da silhueta atual e à insatisfação com a imagem corporal em adultos com obesidade. Métodos Estudo transversal derivado da linha de base de um ensaio clínico randomizado. A percepção de silhueta atual e a insatisfação com a imagem corporal, definida pela diferença entre a percepção da silhueta atual e da ideal, foram obtidas a partir de uma escala variando de um (menor silhueta) a nove pontos (maior silhueta). As variáveis independentes investigadas como fatores associados (regressão linear bruta e ajustada) foram: sexo, idade, cor da pele, índice de massa corporal (kg/m2), percentual de gordura corporal, nível de atividade física e ingestão alimentar. Resultados Foram investigados 69 obesos (índice de massa corporal ≥30kg/m2), sendo 42 do sexo feminino e com os seguintes valores médios: 34,7 (±7,2) anos; 33,5 (±2,8) kg/m2 e silhueta atual de 6,6 (±0,9). Todos estavam insatisfeitos pelo excesso de peso corporal. As categorias que se associaram à percepção da silhueta atual foram o sexo masculino, a cor de pele branca e maiores valores de índice de massa corporal quando comparados os dados referentes ao sexo feminino, a pessoas de cor da pele não branca e a menores valores de índice de massa corporal, respectivamente. Quanto à insatisfação com a imagem corporal, pessoas consideradas brancas tiveram escores mais baixos que aquelas com outras cores de pele. Conclusão Ser do sexo masculino, ter cor da pele branca e ter maior índice de massa corporal foram fatores de risco para a percepção de silhuetas corporais maiores, enquanto apenas a cor da pele não branca esteve associada à insatisfação com a imagem corporal.

https://doi.org/10.1590/1678-9865202336e220116

PAAF vs. BAG en nódulos tiroideos, la experiencia en el Hospital Regional de Antofagasta
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Kratc, Renata

; Vargas, Bryan C.

; Aracena, Joaquín

; Piquimil, Lorena

; Carrasco, Cecilia

Revista chilena de radiología

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dec 2022, Volume 28 N. 4 Pages 128 - 134

Abstract: En | Text: En | PDF: En

Resumen Introducción: La punción aspirativa con aguja fina (PAAF) tiene un papel importante en la evaluación del nódulo tiroideo, siendo un método barato, rápido y poco invasivo, sin embargo su alta tasa de resultados inconclusos o insuficientes hacen que la técnica de biopsia con aguja gruesa (BAG) sea una alternativa atractiva. Objetivo: El objetivo de este estudio es evaluar la precisión diagnóstica de la PAAF vs. la BAG en lesiones tiroideas, contrastando sus resultados con los hallazgos histopatológicos de la pieza quirúrgica. Materiales y métodos: Se realizó un análisis retrospectivo del registro clínico del Hospital Regional de Antofagasta, analizando los estudios de PAAF y BAG entre enero del 2017 y diciembre del 2020. Se incluyeron 293 casos. Se determinó sensibilidad, especificidad, valor predictivo positivo (VPP), valor predictivo negativo (VPN) y precisión diagnóstica (PD). Resultados: La correlación histopatológica mostró una sensibilidad para la PAAF del 67.9%, especificidad del 88.9%, VPP del 86.3%, VPN del 72.7% y PD del 78.2%. Para la BAG la sensibilidad fue 93.3%, especificidad 100%, VPP 100% y VPN 93.8%, con PD del 96.6%. Conclusión: La BAG es una prueba sensible y específica, que disminuye la tasa de resultados no diagnósticos. Los datos obtenidos son comparables con la literatura.

https://doi.org/10.24875/rchrad.22000031

Factores asociados al conocimiento y medidas preventivas de mordedura de Loxosceles laeta en la población de la Encuesta Nacional de Programas Presupuestales (ENAPRES) en el Perú 2017-2019
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Borjas-Aguilar, Samir André

; Esteban-Manrique, Paola Cecilia

; Luna-Muñoz, Consuelo del Rocío

; Chanduvi-Puicón, Willer David

; Cruz-Vargas, Jhony A. De La

Revista chilena de infectología

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oct 2022, Volume 39 N. 5 Pages 565 - 572

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Background: Metaxenic and zoonotic diseases are one of the ten national priorities for health research in Peru 2019-2023. Of these, the cases reported by loxoscelism have been increasing progressively. Aim: To determine the factors associated with the knowledge and preventive measures of Loxosceles laeta bite in the population of the ENAPRES in Peru 2017-2019. Methods: Observational, cross-sectional, analytical and retrospective study, based on information from ENAPRES. Results: A total sample of 285,354 people was analyzed. Of these, those aged 60 or over (PRa=1,48; 95%CI: 1,45-1,51), those from the coast (PRa=1,37; 95%CI: 1,33-1,40), women (PRa=1,12; 95%CI: 1,11-1,13), with primary or secondary education (PRa=1,12; 95%CI: 1,09-1,15), with inadequate housing [ceiling (PRa=1,07; 95%CI: 1,05-1,10), floor (PRa=1,02; 95%CI: 1,00-1,04)], were associated with higher possibility ofhaving more knowledge about L. laeta bite. On the other hand, those aged 60 or over (PRa=1,49; 95%CI: 1,46-1,52), those from the coast (PRa=1,39; 95%CI: 1,35-1,43), with non-university higher education (PRa=1,19; 95%CI: 1,15-1,22), women (PR a=1,13; 95%CI: 1,12-1,14) and with inadequate housing ceilings (PRa=1,07; 95%CI 1,05-1,10) were associated with a greater possibility of taking adequate preventive measures. In both, an association was found between disposing of organic waste on the street or on public roads (RPa=0.97; 95%CI: 0.96-0.99) Conclusions: It were found factors associated with knowledge and preventive for L. laeta bite.

Resumen Introducción: Las enfermedades metaxénicas y zoonóticas, son consideradas prioridades nacionales de investigación en salud en Perú 2019-2023. De estas, los casos reportados por loxoscelismo han ido aumentando progresivamente. Objetivo: Determinar los factores asociados al conocimiento y medidas preventivas de mordedura de Loxosceles laeta en la población de la ENAPRES en el Perú 2017-2019. Métodos: Estudio de tipo observacional, transversal, analítico y retrospectivo, basado en la información de la ENAPRES. Resultados: Se analizó una muestra total de 285.354 personas. De estas, aquellos con 60 a más años (RPa=1,48; IC95%: 1,45-1,51), los costeños (RPa=1,37; IC95%: 1,33-1,40), las mujeres (RPa=1,12; IC95%: 1,11-1,13), con primaria o secundaria (RPa=1,12; IC95%: 1,09-1,15), con viviendas inadecuadas [techo (RPa=1,07; IC95%: 1,05-1,10), piso (RPa=1,02; IC95%: 1,00-1,04)], se asociaron con mayor posibilidad de tener más conocimiento sobre mordedura de L. laeta. Por otra parte, los encuestados de 60 a más años (RPa=1,49; IC95%: 1,46-1,52), los costeños (RPa=1,39; IC95%: 1,35-1,43), con estudios superiores no universitarios (RPa=1,19; IC95%: 1,15-1,22), las mujeres (RPa=1,13; IC95%: 1,12-1,14) y con viviendas con techos inadecuados (RPa=1,07; IC95%: 1,05-1,10) se asociaron con mayor posibilidad de realizar adecuadas medidas preventivas. En ambas, se halló asociación con el desechar los residuos orgánicos en calle o vía pública (RPa=0,97; IC95%: 0,96-0,99). Conclusiones: Se encontró aquellos factores asociados a conocimientos y a las medidas preventivas de mordedura de L. laeta.

Características clínicas, evolución y factores pronósticos asociados con mortalidad en adultos mayores hospitalizados por COVID-19 en una Unidad Geriátrica de Agudos
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Carvacho, Cecilia

; Vargas Donoso, Nadia

; Medina, René

; Gallegos, César

; Carvacho, Raffaela

; Uauy, Olga

; Ward, M. Ignacia

; Márquez-Espinoza, Constanza

; Sanhueza Quiñeman, Juan Pablo

; Gac, Homero

Revista médica de Chile

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sep 2022, Volume 150 N. 9 Pages 1145 - 1151

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Background: SARS-CoV-2 affects all age groups, but higher mortality rates are recorded in older people, men and with comorbidities, mainly hypertension, diabetes and obesity. Aim: To describe the main clinical characteristics, evolution and prognostic factors for death in older patients hospitalized for COVID-19. Materials and Methods: Retrospective analysis of 128 patients aged 73 years, 66% men, hospitalized at a clinical hospital, with a diagnosis of COVID-19, admitted from May 1 to August 1, 2020. Data were collected from the clinical records, a description of the study population was made, and a univariate analysis and logistic regression were performed. Results: Seventy-two percent of patients had two or more comorbidities, mainly arterial hypertension in 66%, diabetes mellitus in 34% and cardiovascular disease in 19%. Forty-one percent were admitted to intensive care and 31% were connected to mechanical ventilation. In-hospital mortality was 26.6%. A multivariate analysis was performed in two blocks, finding in the first that arterial hypertension and older age significantly predict mortality. However, when previous institutionalization and immuno-suppression were included as variables in the second block, age ceased to be a significant predictor. Conclusions: Prognostic factors associated with death in this age group are arterial hypertension and previous institutionalization.

10.

Cemetery Relocations in Hidroituango: An Interdisciplinary Study
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VARGAS, TIMISAY M.

; URIBE, CECILIA L.

; BEDOYA, SANTIAGO V.

; ZAPATA, MARY LUZ Q.

; CARDONA-GALLO, SANTIAGO A.

Anais da Academia Brasileira de Ciências

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2022, Volume 94 N. 1 elocation e20201098

Abstract: En | Text: En | PDF: En

Abstract This study realized the exhumation and transfer of human remains buried in the cemeteries at Orobajo, Barbacoas and La Fortuna (Municipality of Sabanalarga, Peque and Buriticá respectively) within the framework of “Social Management” of the Ituango Hydroelectric Project and the program Integral Restitution of Living Conditions for communities. Methods and techniques from bioanthropology, forensic sciences, archeology and Soil Sciences were used. Cemeteries were characterized by unconventional burials; moreover, documentation of tombs and burial practices were not generalized, nor did they show patterns. In the field assessment, 2,883 pit tests and soil probes using a penetrometer were carried out over a total area of 2,288 square meters. A total of 349 skeletonized human remains were exhumed, almost double of what was expected; of these, 180 were from Orabajo, 151 from Barbacoas, and 18 from La Fortuna. Though the remains showed a great deal of deterioration, age at death was determined for 59% of cases, and sex identified in 49%. Personal artifacts and clothing items were recovered along with the bones in many cases. Remains from Barbacoas and La Fortuna were given over to communities, and final dispositions were made in sites previously agreed upon (cemeteries in Peque, Buriticá and Sabanalarga respectively).

https://doi.org/10.1590/0001-3765202220201098

11.

Consenso mexicano para el diagnóstico y tratamiento de la trombastenia de Glanzmann
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García-Chávez, Jaime

; Hernández-Juárez, Jesús

; Sánchez-Jara, Berenice

; García-Lee, María Teresa

; Rodríguez-Castillejos, Cecilia

; Montiel-Cervantes, Laura

; Moreno-Hernández, Manuel

; Ramos-Blas, Gustavo J.

; Soto-Padilla, Janet M.

; Flores-Villegas, Luz V.

; Pérez-Zúñiga, Juan M.

; López-Arroyo, José L.

; Villarreal-Martínez, Laura

; Madera-Maldonado, Cristina E.

; Herrejón-Carmona, Misael

; Lozano-Garcidueñas, Mónica

; Vargas-Ruiz, Ángel G.

; Hernández-Hernández, Darinel

; Peña-Díaz, Aurora de la

; Aquino-Fernández, Efraín

; Majluf-Cruz, Abraham

Gaceta médica de México

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2022, Volume 158 N. spe4 Pages 1 - 17

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Las plaquetas tienen un papel central en diferentes escenarios fisiológicos, incluyendo la hemostasia; se unen unas con otras en la agregación plaquetaria, lo cual permite formar un coágulo plaquetario. Para que la agregación sea apropiada se requiere del complejo glicoproteico IIb/IIIa (GPIIb/IIIa) en la superficie plaquetaria. Toda alteración funcional plaquetaria, hereditaria o adquirida, impide la formación adecuada del coágulo y se manifiesta como hemorragia. Las enfermedades plaquetarias hereditarias son raras y, hasta recientemente, fueron ignoradas. Una de las más reconocidas y estudiadas es la trombastenia de Glanzmann (TG), entidad en la cual el número de plaquetas puede ser normal pero la función está alterada. Es un padecimiento autosómico y recesivo que causa hemorragia de diferente intensidad toda la vida y en la cual el problema radica en precisamente en la GPIIb/IIIa. Las hemorragias son típicamente mucocutáneas: equimosis, púrpura, epistaxis, gingivorragia; menos frecuentes son la hemorragia gastrointestinal, hemartrosis o en sistema nervioso central. La hiperpolimenorrea es común en las mujeres y llega a ser tan importante que amerita transfusiones en la menarca. La TG afecta a todos los grupos étnicos y su prevalencia varía entre 1/40,000 y 1/400,000. A pesar de esta información acerca de la TG en el mundo, hay pocas guías o recomendaciones basadas en la opinión de expertos y experiencias unicéntricas. En México la TG es rara y no se cuenta con una recomendación general para su diagnóstico y tratamiento. El objetivo de este documento fue establecer un consenso y hacer sugerencias generales para su diagnóstico y tratamiento.

Abstract Platelets have a central role in several physiological scenarios including hemostasis. Platelets bind each other during platelet aggregation allowing the proper formation of the clot; to be appropriate, platelet aggregation requires the glycoproteic complex IIb/IIIa (GPIIb/IIIa). Every platelet function abnormality both, congenital or acquired, impedes clot formation and favors bleeding episodes. Hereditary platelet abnormalities are rare and, until recently, they were almost ignored. Among these disorders, Glanzmann Thrombasthenia (GT) is a widely recognized abnormality in which platelet counts may be normal, but their function is affected. GT is an autosomal, recessive disease that causes life-long bleeding of different intensity. Main biochemical abnormality resides in GPIIb/IIIa. Bleeding is typically mucocutaneous: easy bruising, purpura, and nose and gum bleeds; less frequently are gastrointestinal bleeds, hemarthrosis, or intracranial. Menorrhagia and hyperpolymenorrhea are common findings in in women and may be the cause of anemia requiring blood transfusions at fertile age. GT affects all ethnic groups and its prevalence ranges between 1/40,000 to 1/400,000. Despite this worldwide information regarding GT, only a few guidelines and recommendations have been published, most of them based on expert opinions. In Mexico, GT is rare and there is not a general recommendation regarding its diagnosis and treatment. The aim of this document was to establish a consensus to suggest a general guideline for the diagnosis and treatment of GT in Mexico.

https://doi.org/10.24875/gmm.m22000691

12.

MORBIDITY AND SURVIVAL AFTER PERIOPERATIVE CHEMOTHERAPY IN GASTRIC CANCER: A STUDY USING THE BECKER’S CLASSIFICATION AND REGRESSION
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MACHADO, Maria Cecília de Aguiar

; BARBOSA, José Pedro Coimbra de Vargas Lobarinhas

; OLIVEIRA, Filipa Ferreira de

; BARBOSA, José Adelino Lobarinhas

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2022, Volume 35 elocation e1704

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND: Gastric cancer is an aggressive neoplasm with a poor prognosis. The multimodal approach with perioperative chemotherapy is currently the recommended treatment for patients with locally advanced gastric cancer. This treatment induces a histopathological response expressed either through the degree of regression of the primary tumor or of the lymph nodes or through yTNM staging. Despite its advantages, there are still doubts regarding the effects of chemotherapy on postoperative morbidity and mortality. AIMS: This study aims to evaluate the impact of perioperative chemotherapy and its effect on anatomopathological results and postoperative morbidity and on patient survival. METHODS: This is an observational retrospective study on 134 patients with advanced gastric cancer who underwent perioperative chemotherapy and curative radical surgery. The degree of histological regression of the primary tumor was evaluated according to Becker’s criteria; the proportion of regressed lymph nodes was determined, and postoperative complications were evaluated according to the Clavien-Dindo classification. Survival times were compared between the groups using Kaplan-Meier curves and the Mantel-Cox log-rank test. RESULTS: In all, 22.3% of the patients were classified as good responders and 75.9% as poor responders. This variable was not correlated with operative morbidity (p=1.68); 64.2% of patients had invaded lymph nodes and 46.3% had regressed lymph nodes; and 49.4% had no lymphatic invasion and 61.9% had no signs of venous invasion. Postoperative complications occurred in 30.6% of the patients. The group of good responders had an average survival of 56.0 months and the group of poor responders had 34.0 months (p=0.17). CONCLUSION: Perioperative chemotherapy induces regression in both the primary tumor and lymph nodes. The results of the operative morbidity were similar to those described in the literature. However, although the group of good responders showed better survival, this value was not significant. Therefore, further studies are needed to evaluate the importance of the degree of lymph node regression and its impact on the survival of these patients.

RESUMO RACIONAL: O cancer gástrico é uma neoplasia com mau prognóstico. A abordagem multimodal com quimioterapia-perioperatória é o tratamento recomendado para os pacientes com cancer gástrico localmente avançando. Este tratamento induz uma resposta histopatológica manifestado pelo grau de regressão do tumor primário, dos gânglios linfáticos e do estadiamento ypTNM. Apesar de suas vantagens, ainda há dúvidas quanto aos efeitos da quimioterapia na morbimortalidade pós-operatória. OBJETIVOS: Avaliar o impacto da quimioterapia perioperatória e o seu efeito nos resultados anatomopatológicos, na morbidade pós-operatória e na sobrevida. MÉTODOS: Estudo observacional-retrospetivo com 134 doentes com cancer gástrico avançado, que se submeteram a quimioterapia perioperatória e cirurgia radical curativa. O grau de regressão histológico do tumor primário foi avaliado de acordo com os critérios de Becker. A proporção de gânglios regredidos foi determinada e as complicações pós-operatórias foram avaliadas com a classificação de Clavien-Dindo. Os tempos de sobrevida foram comparados entre os grupos por meio das curvas de Kaplan-Meier e do teste Mantel-Cox Log Rank. RESULTADOS: 22,3% dos doentes foram classificados como bons-respondedores e 75,9% como maus-respondedores. Esta variável e a morbidade pós-operatória não estavam relacionadas. 64,2% dos doentes apresentaram invasão ganglionar e 46,3% tinham regressão ganglionar, 49,4% não tinham invasão linfática e 61,9% não tinham sinais de invasão venosa. As complicações pós-operatórias ocorreram em 30,6% dos pacientes. O grupo dos bons respondedores apresentou uma sobrevida mediana de 56,0 meses e o grupo dos maus respondedores 34,0 meses. CONCLUSÕES: A quimioterapia perioperatória induz a regressão quer do tumor primário e dos gânglios-linfáticos. Os resultados da morbidade pós-operatória foram semelhantes aos descritos na literatura. Apesar do grupo dos bons-respondedores apresentar melhor sobrevida, este valor não foi significativo. Assim, são necessários mais estudos que avaliem a importância do grau de regressão ganglionar e o seu impacto na sobrevida.

https://doi.org/10.1590/0102-672020220002e1704

13.

Guía de práctica clínica para el manejo de cáncer de cuello uterino estadios tempranos
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Malca-Tocas, Mirtha Magaly

; Ugarte-Gil, César

; Matos-Miranda, Claudia Patricia

; Becerra-Chauca, Naysha

; Ceballos-Pacheco, Carlos

; Broncano-Huasasquiche, Oswaldo

; Fernández-Butrón, Ana Cecilia

; Livano-Yberico, Teófilo

; Vargas-Caycho, Yan

; Huaringa-Marcelo, Jorge

; Salvador-Salvador, Stefany

; Timaná-Ruiz, Raúl

; Carrera-Acosta, Lourdes

Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo

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dec 2021, Volume 14 N. 4 Pages 535 - 545

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: This article summarizes the clinical practice guideline (CPG) for the management of early-stage cervical cancer (IA1, IA2, IB1, IB2 o IIA1) in the Social Security of Peru (EsSalud). Objective: To provide clinical recommendations based on evidence for the management of early-stage cervical cancer in EsSalud. Materials and methods: A CPG for the management of early-stage cervical cancer in EsSalud was developed. To this end, a guideline development group (local GDG) was established, including medical specialists and methodologists. The local GDG formulated 8 clinical questions to be answered by this CPG. Systematic searches of systematic reviews and -when it was considered pertinent- primary studies were conducted in Pubmed, Embase y CENTRAL during 2017 - 2018. The evidence to answer each of the posed clinical questions was selected. The quality of the evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In periodic work meetings, the local GDG used the GRADE methodology to review the evidence and formulate the recommendations, points of good clinical practice, and the flowchart of management. Finally, the CPG was approved with Resolution No. N 27-IETSI-ESSALUD-2020. Results: This CPG addressed 8 clinical questions on the management of early-stage cervical cancer (IA1, IA2, IB1, IB2 o IIA1). Based on these questions, 10 recommendations (2 strong recommendations and 8 weak recommendations), 7 points of good clinical practice, and 4 flowcharts were formulated. Conclusion: This article summarizes the methodology and evidence-based conclusions from the CPG for the management of early-stage cervical cancer in EsSalud.

RESUMEN Introducción: Este artículo resume la guía de práctica clínica (GPC) para el manejo de cáncer de cuello uterino estadios tempranos (IA1, IA2, IB1, IB2 o IIA1) en el Seguro Social del Perú (EsSalud). Objetivo: Proveer recomendaciones clínicas basadas en evidencia para el manejo de cáncer de cuello uterino estadios tempranos en EsSalud. Materiales y métodos: Se conformó un grupo elaborador de la guía (GEG) que incluyó médicos especialistas y metodólogos. El GEG formuló 8 preguntas clínicas a ser respondidas por la presente GPC. Se realizó búsquedas sistemáticas de revisiones sistemáticas y -cuando fue considerado pertinente- estudios primarios en Pubmed, Embase y CENTRAL durante el 2017 - 2018. Se seleccionó la evidencia para responder cada una de las preguntas clínicas planteadas. La certeza de la evidencia fue evaluada usando la metodología Grading of Recommendations Assessment, Development, and Evaluation (GRADE). En reuniones de trabajo periódicas, el GEG usó la metodología GRADE para revisar la evidencia y formular las recomendaciones, los puntos de buenas prácticas clínicas y los flujogramas de manejo. Finalmente, la GPC fue aprobada con Resolución N 27-IETSI-ESSALUD-2020. Resultados: La presente GPC abordó 8 preguntas clínicas abordando el manejo del cáncer de cuello uterino en estadios tempranos. En base a dichas preguntas se formularon 10 recomendaciones (2 recomendaciones fuertes y 8 recomendaciones condicionales), 7 puntos de buena práctica clínica, y 4 flujogramas. Conclusión: El presente artículo resume la metodología y las conclusiones basadas en evidencias de la GPC para el manejo del cáncer de cuello uterino en estadios tempranos en EsSalud.

https://doi.org/10.35434/rcmhnaaa.2021.144.1462

14.

Consenso chileno de diagnóstico y manejo de neoplasias quísticas pancreáticas. Club de páncreas Chile-SCHGE
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Espino, Alberto

; Vargas, José Ignacio

; Mancilla, Carla

; Muñoz, Pablo

; Martínez, Waldo

; Menéndez, Alejandra

; Jara, Daniela

; Mansilla, Rodrigo

; Schiappacasse, Giancarlo

; Santamarina, Mario

; Huete, Álvaro

; Candia, Roberto

; Silva, Felipe

; Castillo, Cecilia

; Richter, Hugo

; Mejía, Ricardo

; Vial, Paula

; Robles, Ignacio

; Martínez, Jorge

; Jarufe, Nicolás

; Briceño, Eduardo

; Lembach, Hanns

; Zoroquiain, Pablo

; Roa, Juan Carlos

; Walker, Kenneth

; Torres, Javiera

; Carreño, Laura

; Castiblanco, Adriana

; Fernández, Wanda

; Ríos, Álvaro

; Chandia, Javiera

; Ayala, María José

; Rojas, Tamara

; Verdugo, Jorge

; Berger, Zoltán

Revista médica de Chile

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dec 2021, Volume 149 N. 12 Pages 1773 - 1786

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Pancreatic cystic neoplasms (PCN) are frequently detected on abdominal images performed for non-pancreatic indications. Their prevalence in asymptomatic population ranges from 2.7 to 24.8%, and increases with age. There are several types of pancreatic cysts. Some may contain cancer or have malignant potential, such as mucinous cystic neoplasms, including mucinous cystadenoma (MCN) and intraductal papillary mucinous neoplasms (IPMN). In contrast, others are benign, such as serous cystadenoma (SCA). However, even those cysts with malignant potential rarely progress to cancer. Currently, the only treatment for pancreatic cysts is surgery, which is associated with high morbidity and occasional mortality. The Board of the Chilean Pancreas Club of the Chilean Gastroenterology Society developed the first Chilean multidisciplinary consensus for diagnosis, management, and surveillance of PCN. Thirty experts were invited and answered 21 statements with five possible alternatives: 1) fully agree; 2) partially agree; 3) undecided; 4) disagree and 5) strongly disagree. A consensus was adopted when at least 80% of the sum of the answers “fully agree” and “partially agree” was reached. The consensus was approved by the Board of Directors of the Chilean Pancreas Club for publication.

https://doi.org/10.4067/s0034-98872021001201773 73 downloads

15.

La estructura discursiva de la defensa doctoral en dos corpus orales
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Ainciburu, María Cecilia

; Agray Vargas, Nancy

Andamios

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dec 2021, Volume 18 N. 47 Pages 113 - 145

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La defensa de una tesis doctoral constituye un acto público de relevancia mayor en la vida académica. Cada sede universitaria y país tiene sus convenciones, sin embargo, en todas persiste la estructura de contrapunto propia de la disputatio medieval. Siendo la parte pública de la Defensa un texto oral, no siempre hay la oportunidad de analizar las posiciones argumentativas del candidato y de los miembros del jurado. Esta investigación compara dos corpus orales de defensas doctorales (transcripciones) en inglés y en español, de Estados Unidos y de España (corpus MiCaSe y Nebrija de Comunicación Académica CONCA). El análisis muestra cómo los elementos pragmáticos que caracterizan la situación comunicativa marcan el discurso de sus actores y el nivel de formalidad del discurso.

Abstract The defense of a doctoral thesis is a public act of major importance in academic life. Each university and country have its own conventions, but the counterpoint structure of the medieval disputatio persists in all of them. Since the public part of the Defense is an oral text, there is not always an opportunity to analyze the argumentative positions of the candidate and the members of the jury. This research compares two corpora of doctoral thesis defenses (transcripts) in English and Spanish. They are from different oral traditions, from the United States and Spain. The analysis shows how the pragmatic elements that characterize the communicative situation mark the discourse of its actors and the level of formality of the discourse.

https://doi.org/10.29092/uacm.v18i47.868 25 downloads

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