ABSTRACT Background: This study evaluated the distribution of pine mistletoe in Scots pine ecosystems in relation to topographic variables and land uses. A total of 109 sample plots were selected from pure Scots pine forests in the Eastern Black Sea Region of Turkey. The 6-class dwarf mistletoe rating was used for infection severity. Pearson correlation analysis results showed signiﬁcant relationships between mistletoe infection severity and topographic variables in 30 m buffer and land use in 500 m buffer. Results: Of the sample plots, 69 (63%) were mistletoe infected, and 40 (37%) were uninfected. The t-test results showed that there was a signiﬁcant difference between mean topographic variables and land use in mistletoe infected and uninfected sample plots. The results of the binary logistic regression analysis showed that altitude, productive forest, slope, and road distance were the most signiﬁcant predictors of the distribution of pine mistletoe as topographic variables and land uses. Conclusion: The common direction of mistletoe infected areas, in addition to Scots pine ecosystems, was low altitudes, sheltered valleys, more humid areas and different land use (agriculture, road and stream).