ABSTRACT The objective of this study was to investigate the influence of two cleaning and disinfection programs on broiler performance and on the microbiological status of the facilities. This trial was an observational study of comparative character. Two experiments were conducted, with 960 birds each. Both experiments were carried out in a positive-pressure broiler house. Broilers were distributed in pens equipped with a bell drinker and a tube feeder each. In the first experiment, new wood shavings were used as litter material, and in the second, reused wood shavings were used. Two treatments with16 replicates of 30 birds each were evaluated. The regular treatment consisted of dry and wet organic matter removal, followed by washing. The European treatment consisted of dry organic matter removal, humidification, washing with water under high pressure, detergent application, rinsing, and application of two combined disinfectants: glutaraldehyde 250g/L + formaldehyde 185g/L; p-chlor-m-cresol 210 g/L. Biosecurity measures were adopted during daily management tasks to prevent cross contamination between treatments. The effectiveness of the treatments was evaluated by microbiological analysis performed before and after treatment applications, as well as by broiler performance results. Live performance results were similar between both treatments when broilers were reared on new litter. When reused word-shavings were used as litter material, the European treatment promoted better broiler performance. The European treatment was more effective than the regular treatment in reducing total microbial counts in the facilities when reused wood shavings were used as litter material, and positively influenced broiler performance.

Two cases of cerebral venous thrombosis are reported. Patients were apparently healthy 39 and 28year old females with nonspecific presenting features. Image findings were characteristic of cerebral sinus thrombosis. The younger patient received progesterone to treat placental abruption eight years previously; she had cerebral venous thrombosis while using oral contraception. Both patients had used contraceptive pills for a long time. Oral hormonal contraceptives may increase the risk of vascular events, even in people without personal or family history of venous thrombosis. Modern imaging methods have contributed to early diagnosis, but the possibility of under diagnosis still persists. This report aims to increase the awareness of healthworkers about cerebral venous thrombosis in women, an entity often misdiagnosed, under diagnosed and underreported.

Se informan dos casos de trombosis venosa cerebral. Las pacientes eran mujeres aparentemente saludables, 39 y 28años de edad, con presentación clínica nonespecífica. Los dados de exámenes de imagen eran característicos de trombosis del seno cerebral. La paciente más joven recibió progesterona para tratar desprendimiento de placenta, y ocho años antes había presentado trombosis venosa cerebral mientras usando anticoncepción oral. Ambas pacientes habían usado las píldoras anticoncepcionales durante mucho tiempo. Los contraceptivos hormonales orales pueden aumentar el riesgo de eventos vasculares, incluso en las personas sin antecedente personal o familiar de trombosis venosa. Las nuevas técnicas de imágenes han contribuido al diagnóstico temprano, pero la posibilidad de diagnóstico insospechado todavía persiste. El propósito de este informe es aumentar el índice de sospecha de profesionales de la salud sobre la trombosis venosa cerebral en mujeres, entidad a menudo erróneamente diagnosticada, infradiagnosticada y no reportada.

Este artigo apresenta uma aplicação do método para determinação espectrofotométrica simultânea dos íons divalentes de cobre, manganês e zinco à análise de medicamento polivitamínico/polimineral. O método usa 4-(2-piridilazo) resorcinol (PAR), calibração multivariada e técnicas de seleção de variáveis e foi otimizado o empregando-se o algoritmo das projeções sucessivas (APS) e o algoritmo genético (AG), para escolha dos comprimentos de onda mais informativos para a análise. Com essas técnicas, foi possível construir modelos de calibração por regressão linear múltipla (RLM-APS e RLM-AG). Os resultados obtidos foram comparados com modelos de regressão em componentes principais (PCR) e nos mínimos quadrados parciais (PLS). Demonstra-se a partir do erro médio quadrático de previsão (RMSEP) que os modelos apresentam desempenhos semelhantes ao prever as concentrações dos três analitos no medicamento. Todavia os modelos RLM são mais simples pois requerem um número muito menor de comprimentos de onda e são mais fáceis de interpretar que os baseados em variáveis latentes.

The application of the method for the simultaneous spectrophotometric determination of the divalent ions of copper, manganese and zinc for analysis of a pharmaceutical formulation of polivitaminic/polimineral is reported. This method uses 4-(2-pyridylazo) resorcinol (PAR) and multivariate calibration and was optimized using the successive projections algorithm (SPA) and a genetic algorithm (GA) for choosing the best series of wavelengths for analysis. Thus the construction of calibration models based on multiple linear regression (MLR-SPA and MLR-GA respectively) was made possible. The results obtained were compared with models based on latent variables, principal component regression (PCR) and partial least square regression (PLS) through the criterion of the root mean square error of prediction (RMSEP). All the methods presented even performance but the RLM methods are simpler since they require a smaller number of wavelengths and are easier to interpret than those based on latent variables.

São apresentados alguns dados sobre CPO e MID (Índice de ataque ao 1° molar permanente inferior direito). São estudadas as distribuições do MID e do CPO /MID = 0, ajustando-se a binomial e binomial negativa, respectivamente, tendo o teste de aderência acusado bom ajuste em 10 casos, dos 12 testados.

Data on DMF and right lower first permanent molar (RLM) are presented. Binomial and negative binomial distributions are fitted to the data, and the goodness of fit test indicates good fitting in 10 out of 12 cases.

São apresentados alguns dados sobre CPO e MID (Índice de ataque ao 1° molar permanente inferior direito). São estudadas as distribuições do MID e do CPO /MID = 0, ajustando-se a binomial e binomial negativa, respectivamente, tendo o teste de aderência acusado bom ajuste em 10 casos, dos 12 testados.

Data on DMF and right lower first permanent molar (RLM) are presented. Binomial and negative binomial distributions are fitted to the data, and the goodness of fit test indicates good fitting in 10 out of 12 cases.