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Abstract Among the potential feed additives, β-glucans are known to positively affect the growth performance, blood parameters, and intestinal microbiota of fish, even the ornamental species. Therefore, the present study evaluated the effects of the dietary supplementation of different Saccharomyces cerevisiae β-glucans concentrations (0, 0.05, 0.1, and 0.2%) in juvenile angelfish (Pterophyllum scalare) over a 42-day period. Regarding growth performance, no effects were observed on most parameters. However, 0.2% β-glucans supplementation produced higher condition factor values, indicating a better nutritional status. Furthermore, β-glucans supplementation did not affect blood parameters. Regarding intestinal microbiota, β-glucans supplementation increased the abundance of the potentially beneficial bacterial genus Phascolarctobacterium. The high abundance of bacteria from the phylum Bacteroidetes, which can degrade β-glucans, may be attributed to the increased abundance of Phascolarctobacterium spp. In addition, 0.2% β-glucans supplementation produced more operational taxonomic units and higher Sobs (observed species richness), indicating effects on the overall bacterial community structure. These results demonstrate the potential application of β-glucans as a dietary supplement to improve the performance and modulate the intestinal microbiota of angelfish. additives βglucans β glucans parameters fish Therefore 0, 0 (0 005 05 0.05 01 1 0.1 02 2 Pterophyllum scalare 42day day 42 period However 0.2 values status Furthermore Bacteroidetes βglucans, glucans, spp addition richness, richness , richness) structure ( 00 0.0 0. 4

https://doi.org/10.1590/0001-3765202420231006

In vitro gas production from pearl millet cultivars under nitrogen levels
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FRANÇA, Aldi Fernandes de Souza

; SILVA, Nelson Rafael da

; OLIVEIRA, Leonardo Guimarães

; BRUNES, Ludmilla Costa

; CORRÊA, Daniel Staciarini

; NASSAR, Reginaldo Ferreira

; JACOVETTI, Reginaldo

; SILVA PAUSE, Alzira Gabriela da

Revista Brasileira de Saúde e Produção Animal

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2024, Volume 25 elocation e20230034

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT This study aimed to evaluate the in vitro gas production from three pearl millet cultivars submitted to four nitrogen levels. The treatments consisted of three pearl millet cultivars (ADR 500, ADR 7020, and LABH 70732) and four nitrogen levels (0, 50, 100, and 200 kg/ha), using urea as the nitrogen source. A 3 x 4 factorial experimental design, employing a randomized block setup, was used to assess both gas production and digestibility. No interaction was observed between nitrogen doses and fermentative parameters on in vitro gas production from the dry matter of pearl millet cultivars. Nitrogen had no impact on the dry matter content or chemical composition of the cultivars. Consistency prevailed in the chemical composition across the various cultivars, a trend that extended to the gas production rates for both soluble and insoluble contents. Notably, nitrogen fertilizer exerted an influence on the fermentation pattern of organic matter, gas production, and lag time for the cultivars. Nitrogen fertilization is advised solely for enhancing fermentative attributes in the case of the cultivar ADR 7020. 500 7020 70732 0, 0 (0 50 100 20 kg/ha, kgha kg/ha , kg ha kg/ha) source design setup digestibility contents Notably 702 7073 ( 5 10 2 70 707 1 7

RESUMO Objetivou-se avaliar a produção “in vitro” de gás de três cultivares de milheto forrageiro sob adubação nitrogenada. Os tratamentos foram constituídos por três cultivares de milheto: (ADR 500, ADR 7020 e LABH 70732) e quatro doses de N(ureia) (0; 50; 100 e 200 kg/ha). Para as avaliações da produção de gases e digestibilidade o delineamento experimental foi blocos casualizados em esquema fatorial 3 x 4, com quatro repetições. Não houve interação entre as doses de adubação nitrogenada e os parâmetros fermentativos da produção de gases “in vitro” da matéria seca das cultivares de milheto. A adubação nitrogenada não influenciou os teores de matéria seca ou a composição bromatológica das cultivares. Não houve diferenças na composição bromatológica entre as cultivares. O mesmo foi observado para as taxas de produção de gás a partir do conteúdo solúvel e insolúvel. A adubação nitrogenada influenciou o padrão de fermentação, a produção de gases e o tempo de colonização por bactérias da matéria orgânica das três cultivares. A adubação nitrogenada é recomendada para incrementar as características fermentativas apenas da cultivar ADR 7020. Objetivouse Objetivou se in vitro 500 702 70732 Nureia N ureia N(ureia 0 (0 50 10 20 kg/ha. kgha kg/ha . kg ha kg/ha) 4 repetições insolúvel fermentação 70 7073 ( 5 1 2 7 707

https://doi.org/10.1590/s1519-994020230034

Compatibility and cytotoxicity of poly(ε-caprolactone)/polypyrrole-block-poly(ε-caprolactone) blend films in fibroblast bovine cells polyεcaprolactone/polypyrroleblockpolyεcaprolactone polyεcaprolactonepolypyrroleblockpolyεcaprolactone poly ε caprolactone /polypyrrole block polypyrrole poly(ε-caprolactone)/polypyrrole-block-poly(ε-caprolactone polyεcaprolactone polypyrroleblockpolyεcaprolactone
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Souza, Nelson Luis Gonçalves Dias de

; Cavallini, Grasiele Soares

; Alves, Tiago Teixeira

; Pereira, Michele Munk

; Brandão, Humberto de Mello

; Oliveira, Luiz Fernando Cappa de

Polímeros

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2024, Volume 34 N. 1 elocation e20240007

Abstract: En | Text: En | PDF: En

Abstract Polymer blends, derived from the combination of two or more polymers, yield novel materials with properties distinct from that of the original polymers. These materials have garnered interest in the medical field. However, for such applications the biocompatibility of the material must be evaluated. In this study, we prepared polymer blends from poly(ε-caprolactone) (PCL) and polypyrrole-block-poly(caprolactone) (PPy-b-PCL) using the casting method. The observed compatibility resulted from specific interactions between the carboxylic group of PCL and the amine group of PPy-b-PCL, as well as between the pyrrole ring of PPy-b-PCL and the CH2 group of PCL. Micro-Raman imaging revealed homogeneity in surface morphology, whereas thermogravimetric analysis indicated that the formation of polymer blends enhances the material’s thermal stability. Importantly, the results demonstrated that the addition of PPy-b-PCL does not affect the cytotoxicity to bovine fibroblasts, suggesting their biocompatibility and potential application in cattle veterinary devices. polymers field However evaluated study polyεcaprolactone poly ε caprolactone poly(ε-caprolactone (PCL polypyrroleblockpolycaprolactone polypyrrole block polypyrrole-block-poly(caprolactone PPybPCL PPy b (PPy-b-PCL method PPybPCL, PCL, CH MicroRaman Micro Raman morphology s stability Importantly fibroblasts devices

https://doi.org/10.1590/0104-1428.20230082

Association Between Body Mass Index, Obesity, and Clinical Outcomes Following Coronary Artery Bypass Grafting in Brazil: An Analysis of One Year of Follow-up of BYPASS Registry Patients Index Obesity Brazil Followup Follow up
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Ramos, Rodrigo Santin

; Rocco, Isadora Salvador

; Viceconte, Marcela

; Santo, José Amalth do Espírito

; Berwanger, Otavio

; Santos, Renato Hideo Nakagawa

; Kalil, Renato Abdala Karam

; Jatene, Fabio B.

; Cavalcanti, Alexandre Biasi

; Zilli, Alexandre Cabral

; Pimentel, Walace de Souza

; Hossne Junior, Nelson Américo

; Branco, João Nelson Rodrigues

; Trimer, Renata

; Evora, Paulo Roberto Barbora

; Gomes, Walter J.

; Guizilin, Solange

Brazilian Journal of Cardiovascular Surgery

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2024, Volume 39 N. 2 elocation e20230133

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To investigate the association between body mass index (BMI), obesity, clinical outcomes, and mortality following coronary artery bypass grafting (CABG) in Brazil using a large sample with one year of follow-up from the Brazilian Registry of Cardiovascular Surgeries in Adults (or BYPASS) Registry database. Methods: A multicenter cohort-study enrolled 2,589 patients submitted to isolated CABG and divided them into normal weight (BMI 20.0-24.9 kg/m2), overweight (BMI 25.0-29.9 kg/m2), and obesity (BMI > 30.0 kg/m2) groups. Inpatient postoperative outcomes included the most frequently described complications and events. Collected post-discharge outcomes included rehospitalization and mortality rates within 30 days, six months, and one year of follow-up. Results: Sternal wound infections (SWI) rate was higher in obese compared to normal-weight patients (relative risk [RR]=5.89, 95% confidence interval [CI]=2.37-17.82; P=0.001). Rehospitalization rates in six months after discharge were higher in obesity and overweight groups than in normal weight group (χ2=6.03, P=0.049); obese patients presented a 2.2-fold increase in the risk for rehospitalization within six months compared to normal-weight patients (RR=2.16, 95% CI=1.17-4.09; P=0.045). Postoperative complications and mortality rates did not differ among groups during time periods. Conclusion: Obesity increased the risk for SWI, leading to higher rehospitalization rates and need for surgical interventions within six months following CABG. Age, female sex, and diabetes were associated with a higher risk of mortality. The obesity paradox remains controversial since BMI may not be sufficient to assess postoperative risk in light of more complex and dynamic evaluations of body composition and physical fitness. Objective BMI, , (BMI) (CABG followup follow up or BYPASS database Methods cohortstudy cohort study 2589 2 589 2,58 20.024.9 200249 20.0 24.9 20 0 24 9 20.0-24. kg/m2, kgm2 kgm kg/m2 kg m2 m 25.029.9 250299 25.0 29.9 25 29 25.0-29. 300 30. events postdischarge post 3 days followup. up. Results SWI (SWI normalweight relative RR=5.89, RR589 RR =5.89, 5 89 [RR]=5.89 95 CI=2.3717.82 CI2371782 CI =2.37 17.82 37 17 82 [CI]=2.37-17.82 P=0.001. P0001 P P=0.001 . 001 P=0.001) χ2=6.03, χ2603 χ χ2 6 03 (χ2=6.03 P=0.049 P0049 049 P=0.049) 2.2fold 22fold fold 2.2 RR=2.16, RR216 16 (RR=2.16 CI=1.174.09 CI117409 CI=1.17 4.09 1 4 09 CI=1.17-4.09 P=0.045. P0045 P=0.045 045 P=0.045) periods Conclusion Age sex fitness 258 58 2,5 024 20.024. 20024 200 20. 249 24. 20.0-24 kg/m 029 25.029. 25029 250 25. 299 29. 25.0-29 RR=5.89 RR58 =5.89 8 [RR]=5.8 3717 CI=2.3717.8 CI237178 237 =2.3 1782 17.8 [CI]=2.37-17.8 P000 P=0.00 00 χ2=6.03 χ260 (χ2=6.0 P=0.04 P004 04 2fold 22 2. RR=2.16 RR21 (RR=2.1 174 CI=1.174.0 CI11740 CI117 CI=1.1 409 4.0 CI=1.17-4.0 2, 02 20.024 2002 20.0-2 25.029 2502 25.0-2 RR=5.8 RR5 =5.8 [RR]=5. 371 CI=2.3717. CI23717 23 =2. 178 17. [CI]=2.37-17. P00 P=0.0 χ2=6.0 χ26 (χ2=6. RR=2.1 RR2 (RR=2. CI=1.174. CI1174 CI11 CI=1. 40 4. CI=1.17-4. 20.02 20.0- 25.02 25.0- RR=5. =5. [RR]=5 CI=2.3717 CI2371 =2 [CI]=2.37-17 P0 P=0. χ2=6. (χ2=6 RR=2. (RR=2 CI=1.174 CI1 CI=1 CI=1.17-4 RR=5 =5 [RR]= CI=2.371 CI237 = [CI]=2.37-1 P=0 χ2=6 (χ2= RR=2 (RR= CI= CI=1.17- RR= [RR] CI=2.37 CI23 [CI]=2.37- P= χ2= (χ2 (RR [RR CI=2.3 CI2 [CI]=2.37 (χ CI=2. [CI]=2.3 CI=2 [CI]=2. [CI]=2 [CI]= [CI] [CI

https://doi.org/10.21470/1678-9741-2023-0133

EDUCAÇÃO PÚBLICA NO ATUAL CENÁRIO SÓCIO-POLÍTICO E ECONÔMICO BRASILEIRO SÓCIOPOLÍTICO SÓCIO POLÍTICO
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Moraes, Carmen Sylvia Vidigal

; Leher, Roberto

; Ferretti, Celso João

; Amaral, Nelson Cardoso

; Ximenes, Salomão Barros

; Gomes, Nilma Lino

; Zuin, Antônio Alvaro Soares

; Almeida, Luana Costa

; Almeida, Ana Maria Fonseca de

; Trevisan, Anderson Ricardo

; Dalbosco, Claudio Almir

; Mazza, Débora

; Lima, Licínio Carlos Viana da Silva

; Goergen, Pedro

; Souza, Sandra Maria Zákia Lian

; Rambla, Xavier

; Sisto, Vicente

Educação & Sociedade

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2024, Volume 45 elocation e283572

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.1590/es.283572

Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023 202 20 2
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Feitosa, Audes Diogenes de Magalhães

; Barroso, Weimar Kunz Sebba

; Mion Junior, Decio

; Nobre, Fernando

; Mota-Gomes, Marco Antonio

; Jardim, Paulo Cesar Brandão Veiga

; Amodeo, Celso

; Oliveira, Adriana Camargo

; Alessi, Alexandre

; Sousa, Ana Luiza Lima

; Brandão, Andréa Araujo

; Pio-Abreu, Andrea

; Sposito, Andrei C.

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Rodrigues, Cibele Isaac Saad

; Forjaz, Claudia Lucia de Moraes

; Sampaio, Diogo Pereira Santos

; Barbosa, Eduardo Costa Duarte

; Freitas, Elizabete Viana de

; Cestario, Elizabeth do Espirito Santo

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Feitosa, Fabiana Gomes Aragão Magalhães

; Consolim-Colombo, Fernanda Marciano

; Almeida, Fernando Antônio de

; Silva, Giovanio Vieira da

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Guimarães, Isabel Cristina Britto

; Gemelli, João Roberto

; Barreto-Filho, José Augusto Soares

; Vilela-Martin, José Fernando

; Ribeiro, José Marcio

; Yugar-Toledo, Juan Carlos

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano F.

; Bortolotto, Luiz Aparecido

; Alves, Marco Antonio de Melo

; Malachias, Marcus Vinícius Bolívar

; Neves, Mario Fritsch Toros

; Santos, Mayara Cedrim

; Dinamarco, Nelson

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Vitorino, Priscila Valverde de Oliveira

; Miranda, Roberto Dischinger

; Bezerra, Rodrigo

; Pedrosa, Rodrigo Pinto

; Paula, Rogerio Baumgratz de

; Okawa, Rogério Toshiro Passos

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C.

; Lima, Sandro Gonçalves de

; Inuzuka, Sayuri

; Ferreira-Filho, Sebastião Rodrigues

; Fillho, Silvio Hock de Paffer

; Jardim, Thiago de Souza Veiga

; Guimarães Neto, Vanildo da Silva

; Koch, Vera Hermina Kalika

; Gusmão, Waléria Dantas Pereira

; Oigman, Wille

; Nadruz Junior, Wilson

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 4 elocation e20240113

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20240113

Deficiência de Testosterona em Homens Hipertensos: Prevalência e Fatores Associados Hipertensos
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Negretto, Leandra Analia Freitas

; Rassi, Nelson

; Soares, Leonardo Ribeiro

; Saraiva, Amanda Bueno Carvalho

; Teixeira, Maria Emília Figueiredo

; Santos, Luciana da Ressurreição

; Souza, Ana Luiza Lima

; Jardim, Paulo Cesar B. Veiga

; Barroso de Souza, Weimar Kunz Sebba

; Jardim, Thiago de Souza Veiga

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 3 elocation e20230138

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background: Testosterone deficiency (TD) is a prevalent condition in our midst and still very neglected. Arterial hypertension (AH) is one of the possible associated factors. Objectives: To determine the prevalence of TD in a hypertensive male population and the factors associated with its occurrence, such as age, time since hypertension diagnosis, number of antihypertensive classes, body mass index (BMI), diabetes, dyslipidemia, chronic kidney disease (CKD), positive symptoms of TD (positive ADAM questionnaire) and use of spironolactone. Methods: Cross-sectional study with administration of the ADAM questionnaire, assessment of biochemical, clinical, and anthropometric data. Patients were stratified into DT and normal testosterone groups. Categorical variables were compared using the chi-squared test and continuous variables using the Mann-Witney test; variables with significance (p<0,05) were analyzed by multivariable linear regression. Results: The prevalence of TD was 26.36%. There was an association between TD and body mass index (BMI) (p=0.0007) but there was no association with age (p=0.0520), time of hypertension diagnosis (p=0.1418), number of classes of antihypertensive drugs (p=0.732), diabetes (p=0.1112); dyslipidemia (p=0.3888); CKD (p=0.3321); use of spironolactone (p=0.3546) or positive ADAM questionnaire (p=0.2483). Conclusions: TD was highly prevalent and positively associated with BMI. Total testosterone (TT) declined by 8.44ng/dL with a one unit increase in BMI and dropped by 3.79ng/dL with a one-year increase in age. Background (TD neglected AH (AH Objectives occurrence BMI, , CKD, (CKD) Methods Crosssectional Cross sectional biochemical clinical data groups chisquared chi squared MannWitney Mann Witney p<0,05 p005 p 0 05 (p<0,05 regression Results 2636 26 36 26.36% (BMI p=0.0007 p00007 0007 (p=0.0007 p=0.0520, p00520 p=0.0520 0520 (p=0.0520) p=0.1418, p01418 p=0.1418 1418 (p=0.1418) p=0.732, p0732 p=0.732 732 (p=0.732) p=0.1112 p01112 1112 (p=0.1112) p=0.3888 p03888 3888 (p=0.3888) p=0.3321 p03321 3321 (p=0.3321) p=0.3546 p03546 3546 (p=0.3546 p=0.2483. p02483 p=0.2483 . 2483 (p=0.2483) Conclusions TT (TT 844ngdL ngdL 8 44ng dL ng 379ngdL 3 79ng oneyear year (CKD p<0,0 p00 (p<0,0 263 2 26.36 p=0.000 p0000 000 (p=0.000 p0052 p=0.052 052 (p=0.0520 p0141 p=0.141 141 (p=0.1418 p073 p=0.73 73 (p=0.732 p=0.111 p0111 111 (p=0.1112 p=0.388 p0388 388 (p=0.3888 p=0.332 p0332 332 (p=0.3321 p=0.354 p0354 354 (p=0.354 p0248 p=0.248 248 (p=0.2483 p<0, p0 (p<0, 26.3 p=0.00 p000 00 (p=0.00 p=0.05 (p=0.052 p014 p=0.14 14 (p=0.141 p07 p=0.7 7 (p=0.73 p=0.11 p011 11 (p=0.111 p=0.38 p038 38 (p=0.388 p=0.33 p033 33 (p=0.332 p=0.35 p035 35 (p=0.35 p024 p=0.24 24 (p=0.248 p<0 (p<0 26. p=0.0 (p=0.0 (p=0.05 p01 p=0.1 1 (p=0.14 p=0. (p=0.7 (p=0.11 p=0.3 p03 (p=0.38 (p=0.33 (p=0.3 p02 p=0.2 (p=0.24 p< (p< (p=0. (p=0.1 p=0 (p=0.2 (p (p=0 p= (p=

Resumo Fundamento: A deficiência de testosterona (DT) é uma condição prevalente em nosso meio e ainda muito negligenciada. A hipertensão arterial (HA) é um de seus possíveis fatores associados. Objetivos: Determinar a prevalência de DT em uma população masculina hipertensa e os fatores associados à sua ocorrência, como idade, tempo de diagnóstico de HA, número de classes de anti-hipertensivos, índice de massa corporal (IMC), diabetes, dislipidemia, doença renal crônica (DRC), sintomas positivos de DT (questionário ADAM positivo) e uso de espironolactona. Métodos: Estudo transversal com aplicação do questionário ADAM, e avaliação de dados bioquímicos, clínicos e antropométricos. Os pacientes foram estratificados em grupos de DT e testosterona normal. As variáveis categóricas foram comparadas pelo teste do qui-quadrado e as variáveis contínuas pelo teste de Mann-Witney; as variáveis com significância (p<0,05) foram submetidas à regressão linear multivariada. Resultados: A prevalência de DT foi de 26,8%. Houve associação entre DT e IMC (p=0,0007), mas não houve com idade (p=0,0520), tempo de diagnóstico de HA (p=0,1418), número de classes de anti-hipertensivos (p=0,0732), diabetes (p=0,1112); dislipidemia (p=0,3888); presença de DRC (p=0,3321); uso de espironolactona (p=0,3546) e questionário ADAM positivo (p=0,2483). Conclusões: A prevalência de DT foi alta e houve associação positiva com IMC. A testosterona total (TT) declinou 8,44 ng/dL com o aumento de 1 kg/m2 no IMC e caiu 3,79 ng/dL com o avanço em um ano na idade. Fundamento (DT negligenciada (HA Objetivos ocorrência antihipertensivos, antihipertensivos anti hipertensivos, hipertensivos IMC, , (IMC) DRC, (DRC) Métodos bioquímicos antropométricos normal quiquadrado qui quadrado MannWitney Mann Witney Mann-Witney p<0,05 p005 p 0 05 (p<0,05 multivariada Resultados 268 26 8 26,8% p=0,0007, p00007 p=0,0007 0007 (p=0,0007) p=0,0520, p00520 p=0,0520 0520 (p=0,0520) p=0,1418, p01418 p=0,1418 1418 (p=0,1418) p=0,0732, p00732 p=0,0732 0732 (p=0,0732) p=0,1112 p01112 1112 (p=0,1112) p=0,3888 p03888 3888 (p=0,3888) p=0,3321 p03321 3321 (p=0,3321) p=0,3546 p03546 3546 (p=0,3546 p=0,2483. p02483 p=0,2483 . 2483 (p=0,2483) Conclusões TT (TT 844 44 8,4 ngdL ng dL kgm2 kgm kg m2 m kg/m 379 3 79 3,7 (IMC (DRC p<0,0 p00 (p<0,0 2 26,8 p0000 p=0,000 000 (p=0,0007 p0052 p=0,052 052 (p=0,0520 p0141 p=0,141 141 (p=0,1418 p0073 p=0,073 073 (p=0,0732 p=0,111 p0111 111 (p=0,1112 p=0,388 p0388 388 (p=0,3888 p=0,332 p0332 332 (p=0,3321 p=0,354 p0354 354 (p=0,354 p0248 p=0,248 248 (p=0,2483 84 4 8, 37 7 3, p<0, p0 (p<0, 26, p000 p=0,00 00 (p=0,000 p=0,05 (p=0,052 p014 p=0,14 14 (p=0,141 p007 p=0,07 07 (p=0,073 p=0,11 p011 11 (p=0,111 p=0,38 p038 38 (p=0,388 p=0,33 p033 33 (p=0,332 p=0,35 p035 35 (p=0,35 p024 p=0,24 24 (p=0,248 p<0 (p<0 p=0,0 (p=0,00 (p=0,05 p01 p=0,1 (p=0,14 (p=0,07 (p=0,11 p=0,3 p03 (p=0,38 (p=0,33 (p=0,3 p02 p=0,2 (p=0,24 p< (p< p=0, (p=0,0 (p=0,1 (p=0, (p=0,2 (p p=0 (p=0 p= (p=

https://doi.org/10.36660/abc.20230138

Retrospective analysis of 1,203 cases of referral to a quaternary vascular surgery outpatient clinic within the Unified Health System, São Paulo, Brazil 1203 1 203 1,20 System Paulo 120 20 1,2 12 2 1,
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Portela, Felipe Soares Oliveira

; Rossetti, Carlos Augusto

; Souza, Thulio Fernandes de

; Magnani, Arthur Souza

; Silva, Marcelo Fiorelli Alexandrino da

; Portugal, Maria Fernanda Cassino

; Teivelis, Marcelo Passos

; Wolosker, Nelson

; Mendes, Cynthia de Almeida

einstein (São Paulo)

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2024, Volume 22 elocation eAO0676

Abstract: En | Text: En | PDF: En

ABSTRACT Objective Consequently, in this study, we aimed to evaluate 1,203 cases of referral to a quaternary vascular surgical service, in São Paulo, Brazil, over a 6-year period, to assess the appropriate need for referral; in addition to the prevalence of surgical indications. Methods In this retrospective analysis, we reviewed the institutional records of participants referred from Basic Healthcare Units to a vascular surgical service inside the Brazilian Unified Health System, between May 2015 and December 2020. Demographic and clinical data were collected. The participants were stratified, as per the reason for referral to the vascular surgical service, previous imaging studies, and surgical treatment indications. Referral appropriateness and complementary examinations were evaluated for each disease cohort. Finally, the prevalence of cases requiring surgical treatment was defined as the outcome measure. Results Of the 1,203 referrals evaluated, venous disease was the main reason for referral (53%), followed by peripheral arterial disease (19.4%). A considerable proportion of participants had been referred without complementary imaging or after a long duration of undergoing an examination. Referrals were regarded as inappropriate in 517 (43%) cases. Of these, 32 cases (6.2%) had been referred to the vascular surgical service, as the incorrect specialty. The percentage of referred participants who ultimately underwent surgical treatment was 39.92%. Carotid (18%) and peripheral arterial diseases (18.4%) were correlated with a lower prevalence of surgical treatments. Conclusion The rate of referral appropriateness to specialized vascular care from primary care settings was low. This may represent a subutilization of quaternary surgical services, with low rates of surgical treatment. Consequently study 1203 1 203 1,20 Paulo Brazil 6year year 6 period indications analysis System 201 2020 collected stratified studies cohort Finally measure 53%, 53 53% , (53%) 19.4%. 194 19.4% . 19 4 (19.4%) examination 51 43% 43 (43% these 3 6.2% 62 2 (6.2% specialty 3992 39 92 39.92% 18% 18 (18% 18.4% 184 (18.4% treatments services 120 20 1,2 202 5 (53% 19.4 (19.4% (43 6.2 (6.2 399 9 39.92 (18 18.4 (18.4 12 1, (53 19. (19.4 (4 6. (6. 39.9 (1 18. (18. (5 (19. ( (6 39. (19

https://doi.org/10.31744/einstein_journal/2024ao0676

ARE THERE ADVANTAGES IN DOUBLE TRANSIT RECONSTRUCTION AFTER TOTAL GASTRECTOMY IN PATIENTS WITH GASTRIC CANCER? A SYSTEMATIC REVIEW CANCER
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COSTA, Luigi Carlo da Silva

; MACEDO, Ary Augusto de Castro

; ARAÚJO, Juliana Mattei de

; SILVA, Ewerton Lima da

; MORAES, Luís Felipe Gomes Reis de

; SANTOS, Aline dos

; SOARES, Hugo Gomes

; TERCIOTI JUNIOR, Valdir

; COELHO NETO, João de Souza

; ANDREOLLO, Nelson Adami

; LOPES, Luiz Roberto

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2024, Volume 37 elocation e1799

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND: Curative treatment for gastric cancer involves tumor resection, followed by transit reconstruction, with Roux-en-Y being the main technique employed. To permit food transit to the duodenum, which is absent in Roux-en-Y, double transit reconstruction has been used, whose theoretical advantages seem to surpass the previous technique. AIMS: To compare the clinical evolution of gastric cancer patients who underwent total gastrectomy with Roux-en-Y and double tract reconstruction. METHODS: A systematic review was carried out on Web of Science, Scopus, EmbasE, SciELO, Virtual Health Library, PubMed, Cochrane, and Google Scholar databases. Data were collected until June 11, 2022. Observational studies or clinical trials evaluating patients submitted to double tract (DT) and Roux-en-Y (RY) reconstructions were included. There was no temporal or language restriction. Review articles, case reports, case series, and incomplete texts were excluded. The risk of bias was calculated using the Cochrane tool designed for randomized clinical trials. RESULTS: Four studies of good methodological quality were included, encompassing 209 participants. In the RY group, there was a greater reduction in food intake. In the DT group, the decrease in body mass index was less pronounced compared to preoperative values. CONCLUSIONS: The double tract reconstruction had better outcomes concerning body mass index and the time until starting a light diet; however, it did not present any advantages in relation to nutritional deficits, quality of life, and post-surgical complications. BACKGROUND resection RouxenY Roux en Y employed duodenum RouxenY, Y, used AIMS METHODS Science Scopus EmbasE SciELO Library PubMed databases 11 2022 (DT (RY included restriction articles reports series excluded RESULTS 20 participants group intake values CONCLUSIONS diet however deficits life postsurgical post surgical complications 1 202 2

RESUMO RACIONAL: O tratamento curativo do câncer gástrico envolve a ressecção do tumor, seguida de reconstrução do trânsito, sendo o Y-de-Roux a principal técnica empregada. Para permitir o trânsito alimentar para o duodeno, ausente em Y-de-Roux, tem-se utilizado a reconstrução de duplo trânsito, cujas vantagens teóricas parecem superar a técnica anterior. OBJETIVOS: Comparar a evolução clínica de pacientes com câncer gástrico submetidos à gastrectomia total com Y-de-Roux e reconstrução de duplo trânsito. MÉTODOS: Foi realizada uma revisão sistemática nas bases de dados: Web of Science, Scopus, Embase, Scielo, Biblioteca Virtual em Saúde, PubMed e Cochrane. Os dados foram coletados até 11 de junho de 2022. Foram incluídos estudos observacionais ou ensaios clínicos avaliando pacientes que utilizaram reconstruções de duplo trânsito (DT) e Y-de-Roux (RY). Não houve restrição temporal ou de idioma. Foram excluídos artigos de revisão, relatos de casos, séries de casos e aqueles com texto incompleto. O risco de viés foi calculado utilizando a ferramenta Cochrane desenvolvida para ensaios clínicos randomizados. RESULTADOS: Foram incluídos quatro estudos de boa qualidade metodológica, abrangendo 209 participantes. No grupo RY houve maior redução na ingestão alimentar. No grupo DT, a diminuição do índice de massa corporal (IMC) foi menos pronunciada em comparação aos valores pré-operatórios. CONCLUSÕES: A reconstrução de duplo trânsito apresentou melhores resultados em relação ao índice de massa corporal e ao tempo para início de dieta leve, porém não apresentou vantagens em relação aos déficits nutricionais, qualidade de vida e complicações pós-cirúrgicas. RACIONAL tumor YdeRoux Y Roux empregada duodeno YdeRoux, Roux, temse tem se anterior OBJETIVOS MÉTODOS Science Scopus Embase Scielo Saúde 1 2022 DT (DT RY. . (RY) idioma incompleto randomizados RESULTADOS metodológica 20 participantes IMC (IMC préoperatórios. préoperatórios pré operatórios. operatórios pré-operatórios CONCLUSÕES leve nutricionais póscirúrgicas. póscirúrgicas pós cirúrgicas. cirúrgicas pós-cirúrgicas 202 (RY 2

https://doi.org/10.1590/0102-672020240006e1799

10.

How can we reduce maternal mortality due to preeclampsia? The 4P rule preeclampsia P
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Korkes, Henri Augusto

; Cavalli, Ricardo Carvalho

; Oliveira, Leandro Gustavo De

; Ramos, José Geraldo Lopes

; Martins Costa, Sérgio Hofmeister de Almeida

; Sousa, Francisco Lázaro Pereira de

; Vieira da Cunha Filho, Edson

; de Souza Mesquita, Maria Rita

; Dias Corrêa Júnior, Mário

; Pinheiro Fernandes Araújo, Ana Cristina

; Zaconeta, Alberto Carlos Moreno

; Freire, Carlos Henrique Esteves

; Poli de Figueiredo, Carlos Eduardo

; Rocha Filho, Edilberto Alves Pereira da

; Sass, Nelson

; Peraçoli, José Carlos

; Costa, Maria Laura

Revista Brasileira de Ginecologia e Obstetrícia

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2024, Volume 46 elocation e-rbgo43

Abstract: En | Text: En | PDF: En

Abstract In low and middle-income countries such as Brazil, most maternal deaths are related to hypertensive complications. Preeclampsia is the leading cause of maternal mortality and morbidity. Significant proportion is associated with the following factors: lack of identification of high-risk women, lack of adequate prevention, difficulty in maintaining a high-risk prenatal follow-up, delayed diagnosis, insecurity and low use of magnesium sulphate, delayed pregnancy interruption and lack of postpartum follow-up of these high-risk cases. Four major actions are proposed to minimize this alarming clinical picture and reduce the mortality rates due to preeclampsia, called the "4 P Rule" (Adequate Prevention – Vigilant Prenatal Care – Timely Delivery (Parturition) – Safe Postpartum). From this simple "rule" we can open a range of important processes and reminders that may help in the guidance of preeclampsia management. middleincome middle income Brazil complications morbidity factors highrisk high risk women prevention followup, followup follow up, up diagnosis sulphate cases 4 " Rule Adequate Parturition (Parturition Postpartum. Postpartum . Postpartum) rule "rule management

https://doi.org/10.61622/rbgo/2024rbgo43

11.

Curva de Aprendizagem da Mortalidade Hospitalar da Substituição da Válvula Aórtica Transcateter: Insights do Registro Nacional Brasileiro Transcateter
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Bernardi, Fernando Luiz de Melo

; Abizaid, Alexandre A.

; Brito Jr, Fábio Sândoli de

; Lemos, Pedro A.

; Siqueira, Dimytri Alexandre Alvim de

; Costa, Ricardo Alves

; Leite, Rogério Eduardo Gomes Sarmento

; Mangione, Fernanda Marinho

; Thiago, Luiz Eduardo Koenig São

; Mangione, José A.

; Lima, Valter Correia de

; Oliveira, Adriano Dourado

; Marino, Marcos Antônio

; Cardoso, Carlos José Francisco

; Caramori, Paulo R. A.

; Tumelero, Rogério

; Portela, Antenor Lages Fortes

; Prudente, Mauricio

; Henriques, Leônidas Alvarenga

; Souza, Fabio Solano

; Bezerra, Cristiano Guedes

; Prado Jr, Guy F. A.

; Freitas, Leandro Zacaris Figueiredo

; Nogueira, Ederlon Ferreira

; Meireles, George César Ximenes

; Pope, Renato Bastos

; Guerios, Enio

; Andrade, Pedro Beraldo de

; Santos, Luciano de Moura

; Marchi, Mauricio Felippi de Sá

; Fundão, Nelson Henrique Fantin

; Ribeiro, Henrique Barbosa

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 7 elocation e20230622

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Robust data on the learning curve (LC) of transcatheter aortic valve replacement (TAVR) are lacking in developing countries. Objective To assess TAVR’s LC in Brazil over time. Methods We analyzed data from the Brazilian TAVR registry from 2008 to 2023. Patients from each center were numbered chronologically in case sequence numbers (CSNs). LC was performed using restricted cubic splines adjusted for EuroSCORE-II and the use of new-generation prostheses. Also, in-hospital outcomes were compared between groups defined according to the level of experience based on the CSN: 1st to 40th (initial-experience), 41st to 80th (early-experience), 81st to 120th (intermediate-experience), and over 121st (high-experience). Additional analysis was performed grouping hospitals according to the number of cases treated before 2014 (>40 and ≤40 procedures). The level of significance adopted was <0.05. Results A total of 3,194 patients from 25 centers were included. Mean age and EuroSCORE II were 80.7±8.1 years and 7±7.1, respectively. LC analysis demonstrated a drop in adjusted in-hospital mortality after treating 40 patients. A leveling off of the curve was observed after case #118. In-hospital mortality across the groups was 8.6%, 7.7%, 5.9%, and 3.7% for initial-, early-, intermediate-, and high-experience, respectively (p<0.001). High experience independently predicted lower mortality (OR 0.57, p=0.013 vs. initial experience). Low-volume centers before 2014 showed no significant decrease in the likelihood of death with gained experience, whereas high-volume centers had a continuous improvement after case #10. Conclusion A TAVR LC phenomenon was observed for in-hospital mortality in Brazil. This effect was more pronounced in centers that treated their first 40 cases before 2014 than those that reached this milestone after 2014. (LC (TAVR countries TAVRs s time 200 2023 CSNs. CSNs . (CSNs) EuroSCOREII newgeneration new generation prostheses Also inhospital hospital CSN st th initialexperience, initialexperience , (initial-experience) earlyexperience, earlyexperience early (early-experience) intermediateexperience, intermediateexperience intermediate (intermediate-experience) highexperience. highexperience high (high-experience) 201 >40 (>4 ≤4 procedures. procedures procedures) 005 0 05 <0.05 3194 3 194 3,19 2 included 80781 80 7 8 1 80.7±8. 771 7±7.1 4 118 #118 Inhospital In 86 6 8.6% 77 7.7% 59 5 9 5.9% 37 3.7 initial, initial- early, early- intermediate, intermediate- highexperience, high-experience p<0.001. p0001 p p<0.001 001 (p<0.001) OR 057 57 0.57 p0013 013 p=0.01 vs experience. experience) Lowvolume Low volume highvolume 10 #10 20 202 (CSNs (initial-experience (early-experience (intermediate-experience (high-experience >4 (> ≤ 00 <0.0 319 19 3,1 8078 80.7±8 7±7. 11 #11 8.6 7.7 5.9 3. p000 p<0.00 (p<0.001 0.5 p001 01 p=0.0 #1 > ( <0. 31 3, 807 80.7± 7±7 8. 7. 5. p00 p<0.0 (p<0.00 0. p=0. # <0 80.7 7± p0 p<0. (p<0.0 p=0 < 80. p<0 (p<0. p= p< (p<0 (p< (p

Resumo Fundamento Dados robustos sobre a curva de aprendizagem (LC) da substituição da válvula aórtica transcateter (TAVR) são escassos nos países em desenvolvimento. Objetivo Avaliar a LC da TAVR no Brasil ao longo do tempo. Métodos Analisamos dados do registro brasileiro de TAVR de 2008 a 2023. Pacientes de cada centro foram numerados cronologicamente em número sequencial de caso (NSC). A LC foi realizada usando um spline cúbico restrito ajustado para o EuroSCORE-II e o uso de próteses de nova geração. Ainda, os desfechos hospitalares foram comparados entre grupos definidos de acordo com o nível de experiência, com base no NSC: 1º ao 40º caso (experiência inicial), 41º ao 80º caso (experiência básica), 81º ao 120º caso (experiência intermediária) e 121º caso em diante (experiência alta). Análises adicionais foram conduzidas de acordo com o número de casos tratados antes de 2014 (>40 e ≤40 procedimentos). O nível de significância adotado foi p <0,05. Resultados Foram incluídos 3194 pacientes de 25 centros. A idade média foi 80,7±8,1 anos e o EuroSCORE II médio foi 7±7,1. A análise da LC demonstrou uma queda na mortalidade hospitalar ajustada após o tratamento de 40 pacientes. Um patamar de nivelamento na curva foi observado após o caso 118. A mortalidade hospitalar entre os grupos foi 8,6%, 7,7%, 5,9%, e 3,7% para experiência inicial, básica, intermediária e alta, respectivamente (p<0,001). A experiência alta foi preditora independente de mortalidade mais baixa (OR 0,57, p=0,013 vs. experiência inicial). Centros com baixo volume de casos antes de 2014 não mostraram uma redução significativa na probabilidade de morte com o ganho de experiência, enquanto centros com alto volume de casos antes de 2014 apresentaram uma melhora contínua após o caso de número 10. Conclusão Observou-se um fenômeno de LC para a mortalidade hospitalar do TAVR no Brasil. Esse efeito foi mais pronunciado em centros que trataram seus 40 primeiros casos antes de 2014 que naqueles que o fizeram após 2014. (LC (TAVR desenvolvimento tempo 200 2023 NSC. NSC . (NSC) EuroSCOREII geração Ainda º inicial , inicial) básica básica) alta. alta) 201 >40 (>4 ≤4 procedimentos. procedimentos procedimentos) 005 0 05 <0,05 319 2 80781 80 7 8 1 80,7±8, 771 7±7,1 4 118 86 6 8,6% 77 7,7% 59 5 9 5,9% 37 3 3,7 p<0,001. p0001 p<0,001 001 (p<0,001) OR 057 57 0,57 p0013 013 p=0,01 vs inicial. 10 Observouse Observou se 20 202 (NSC >4 (> ≤ 00 <0,0 31 8078 80,7±8 7±7, 11 8,6 7,7 5,9 3, p000 p<0,00 (p<0,001 0,5 p001 01 p=0,0 > ( <0, 807 80,7± 7±7 8, 7, 5, p00 p<0,0 (p<0,00 0, p=0, <0 80,7 7± p0 p<0, (p<0,0 p=0 < 80, p<0 (p<0, p= p< (p<0 (p< (p

https://doi.org/10.36660/abc.20230622

12.

Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast Brazil
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Moura Neto, José Pereira

; Albuquerque, Cinthia Cristina Matheus Xerez

; Yahouedehou, Setondji Cocou Modeste Alexandre

; Francisco, Marcos Vinicius Lima

; Fraiji, Nelson Abrahim

; Siqueira, Isadora Cristina de

; Goncalves, Marilda Souza

Brazilian Journal of Infectious Diseases

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2024, Volume 28 N. 2 elocation 103741

Abstract: En | Text: En | PDF: En

ABSTRACT Sickle Cell Disease (SCD) is a hereditary disease characterized by extravascular and intravascular hemolysis and clinical variability, from mild pain to potentially life-threatening. Arboviruses include mainly Zika (ZIKV), Chikungunya (CHKV), and Dengue (DENV) virus, and are considered a public and social health problem. The present cross-sectional observational study aimed to investigate the prevalence of arbovirus infection in SCD patients from two Brazilian cities, Salvador and Manaus located in Bahia and Amazonas states respectively. A total of409 individuals with SCD were included in the study, and 307 (75.06 %) patients tested positive for DENV-IgG, 161 (39.36 %) for ZIKV-IgG, and 60 (14.67 %) for CHIKV-IgG. Only one individual was positive for DENV-NS1 and another for DENV-IgM, both from Salvador. No individuals had positive serology for ZIKV-IgM or CHIKV-IgM. Arbovirus positivity by IgG testing revealed that the SCD group presented high frequencies in both cities. Interestingly, these differences were only statistically significant for ZIKV-IgG (p = 0.023) and CHIKV-IgG (p = 0.005) among SCD patients from Manaus. The reshaping of arbovirus from its natural habitat by humans due to disorderly urban expansion and the ease of international Mobility has been responsible for facilitating the spread of vector-borne infectious diseases in humans. We found the need for further studies on arboviruses in this population to elucidate the real association and impact, especially in acute infection. We hope that this study will contribute to improvements in the personalized clinical follow-up of SCD patients, identifying the influence of arbovirus infection in severe disease manifestations. (SCD variability lifethreatening. lifethreatening life threatening. threatening life-threatening ZIKV, ZIKV , (ZIKV) CHKV, CHKV (CHKV) DENV (DENV virus problem crosssectional cross sectional cities respectively of40 30 75.06 7506 75 06 (75.0 % DENVIgG, DENVIgG IgG, DENV-IgG 16 39.36 3936 39 36 (39.3 ZIKVIgG, ZIKVIgG 6 14.67 1467 14 67 (14.6 CHIKVIgG. CHIKVIgG CHIKV IgG. DENVNS1 DENVNS NS1 NS DENV-NS DENVIgM, DENVIgM IgM, IgM DENV-IgM ZIKVIgM CHIKVIgM. CHIKVIgM IgM. CHIKV-IgM Interestingly p 0.023 0023 0 023 0.005 0005 005 vectorborne vector borne impact followup follow up manifestations (ZIKV (CHKV of4 3 75.0 750 7 (75. 1 39.3 393 (39. 14.6 146 (14. 0.02 002 02 0.00 000 00 75. (75 39. (39 14. (14 0.0 (7 (3 (1 0. (

https://doi.org/10.1016/j.bjid.2024.103741

13.

Thymidine-dependent Staphylococcus aureus and lung function in patients with cystic fibrosis: a 10-year retrospective case-control study Thymidinedependent Thymidine dependent fibrosis 10year year 10 casecontrol case control 1
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Tomaz, Ana Paula de Oliveira

; Souza, Dilair Camargo de

; Cogo, Laura Lucia

; Palmeiro, Jussara Kasuko

; Nogueira, Keite da Silva

; Petterle, Ricardo Rasmussen

; Riedi, Carlos Antonio

; Rosario Filho, Nelson Augusto

; Dalla-Costa, Libera Maria

Jornal Brasileiro de Pneumologia

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2024, Volume 50 N. 4 elocation e20240026

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: Thymidine-dependent small-colony variants (TD-SCVs) of Staphylococcus aureus are being isolated with increasing frequency from patients with cystic fibrosis (CF). The aim of this study was to evaluate the relationship between TD-SCV isolation and pulmonary function in patients with CF, as well as to determine whether the emergence of TD-SCVs was associated with trimethoprim-sulfamethoxazole (TMP-SMX) use and with coinfection with other microorganisms. Methods: This was a retrospective case-control study including patients with CF who visited the Clinical Hospital Complex of the Federal University of Paraná, in Curitiba, Brazil, between 2013 and 2022. Demographic, clinical, and spirometric data, as well as information on TD-SCVs and other isolated microorganisms, were collected from the medical records of patients with CF and TD-SCVs (TD-SCV group; n = 32) and compared with those of a matched group of patients with CF without TD-SCVs (control group; n = 64). Results: Isolation of TD-SCVs was positively associated with TMP-SMX use (p = 0.009), hospitalization (p < 0.001), and impaired pulmonary function (p = 0.04). Conclusions: The use of TMP-SMX seems to contribute to the emergence of TD-SCVs, the isolation of which was directly associated with worse pulmonary function in our sample. Objective Thymidinedependent Thymidine dependent smallcolony small colony TDSCVs TD SCVs (TD-SCVs CF. . (CF) TDSCV SCV trimethoprimsulfamethoxazole trimethoprim sulfamethoxazole TMPSMX TMP SMX (TMP-SMX microorganisms Methods casecontrol case control Paraná Curitiba Brazil 201 2022 Demographic clinical data 32 64. 64 64) Results p 0.009, 0009 0.009 , 0 009 0.009) 0.001, 0001 0.001 001 0.001) 0.04. 004 0.04 04 0.04) Conclusions TDSCVs, SCVs, sample (CF 20 202 3 6 000 0.00 00 0.0 2 0.

https://doi.org/10.36416/1806-3756/e20240026

14.

HIV acute infection and long-term undisclosed HIV status among blood donors from the highly endemic Amazonas state, located in the Brazilian Amazon longterm long term state
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Souza, Maria lvaldete Siqueira de

; Crispim, Myuki Alfaia Esashika

; Fraiji, Nelson Abrahim

; Silva-Junior, Alexander Leonardo

; Stefani, Mariane Martins de Araújo

Brazilian Journal of Infectious Diseases

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2024, Volume 28 N. 4 elocation 103848

Abstract: En | Text: En | PDF: En

ABSTRACT Background: The Amazonas state/AM and Manaus rank among the highest AIDS detection rates in Brazil. High proportion of HIV infected blood donors and transmission clusters of multidrug antiretroviral/ARV resistant viruses were described in HEMOAM blood donors, a main Amazonas public blood bank. Recent and long-term infections among previously genotyped donors are reported. Methods/materials: The recency immunoassay Lag Avidity EIA (Maxim, USA) was employed. Clinical/CD4/viral load medical file data of the main local HIV management center (FMTHVD) and ARV treatment/ART data were reviewed. Results: Among 142 HIV-blood donors, chronic infection predominated (n = 87; 61.3 %), 79 based on LAg EIA and 8 undisclosed HIV identified in FMT-HVD records, mostly young adult, single males, 4 repeat donors, all ART-naive. Recent infections represented 30.3 % (n = 43),39 identified by LAg EIA and 4 immunologic windows (antibody negative/NAT/RNA positive). The overall profile of recent and long-term infections was similar, including moderate rate of transmitted drug resistance/TDR, however with multiple resistance mutations to more than one ARV-class, suggesting ART/failure. Discussion: Recent/acute and undisclosed/long-term HIV infections represent blood safety alerts suggesting test-seeking behavior of at-risk populations. Early ART use in Brazil, can turn HIV diagnosis more challenging representing a blood transfusion risk in the highly endemic Brazilian Amazon. Background stateAM state AM Brazil antiretroviralARV antiretroviral bank longterm long term reported Methods/materials Methodsmaterials Methods materials Maxim, Maxim (Maxim USA employed ClinicalCD4viral ClinicalCDviral Clinical CD4 viral CD FMTHVD (FMTHVD treatmentART treatment reviewed Results 14 HIVblood n 87 613 61 3 61. %, , %) 7 FMT HVD records adult males ARTnaive. ARTnaive naive. naive ART-naive 303 30 30. 43,39 4339 43 ,39 39 43),3 antibody negativeNATRNA negative NAT RNA positive. positive . positive) similar resistanceTDR TDR resistance/TDR ARVclass, ARVclass class, class ARV-class ARTfailure failure ART/failure Discussion Recentacute acute undisclosed/longterm undisclosedlongterm undisclosed/long testseeking test seeking atrisk at populations Amazon ClinicalCD 1 6 43,3 433 ,3 43), undisclosedlong 43, 43)

https://doi.org/10.1016/j.bjid.2024.103848

15.

Coleoptera of Brazil: what we knew then and what we know now. Insights from the Catálogo Taxonômico da Fauna do Brasil Brazil now
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Caron, Edilson

; Monné, Marcela L.

; Ferreira, Vinicius S.

; Costa, Cleide

; Cupello, Mario

; Aloquio, Sergio

; Linzmeier, Adelita M.

; Vaz-de-Mello, Fernando Z.

; Leivas, Fernando W.T.

; Souza-Gonçalves, Igor

; Mermudes, José R.M.

; Almeida, Lúcia M.

; Moura, Luciano de A.

; Ferreira Júnior, Nelson

; Grossi, Paschoal C.

; Vanin, Sergio A.

; Ślipiński, Adam

; Anichtchenko, Alexander

; Newton, Alfred F.

; Sampaio, Aline

; Carelli, Allan

; Puker, Anderson

; Ferreira, André da S.

; Fernandes, André S.

; Roza, André S.

; Cline, Andrew

; Sampaio, Brunno H.L.

; Clarkson, Bruno

; Castro, Camila F. de

; Bicho, Carla de L.

; Benetti, César J.

; Ribeiro-Costa, Cibele S.

; Lopes-Andrade, Cristiano

; Manfio, Daiara

; Colpani, Daniara

; Basílio, Daniel S.

; Bená, Daniela de C.

; Pollock, Darren A.

; Souza, Diego de S.

; Rodrigues, Diego F.

; Chandler, Donald S.

; Nascimento, Elynton A. do

; Spiessberger, Erich L.

; Agrain, Federico A.

; Barbosa, Felipe F.

; Shockley, Floyd

; Nascimento, Francisco E. de L.

; Biffi, Gabriel

; Powell, Gareth S.

; Morse, Geoffrey E.

; Flores, Gustavo E.

; Escalona, Hermes

; Quintino, Hingrid Y.S.

; Rainho, Hugo L.

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Zoologia (Curitiba)

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2024, Volume 41 elocation e23072

Abstract: En | Text: En | PDF: En

ABSTRACT In 2000, Cleide Costa published a paper presenting the state of knowledge of the Neotropical Coleopte ra, with a focus on the Brazilian fauna. Twenty-four years later, thanks to the development of the Coleoptera section of the Taxonomic Catalog of the Brazilian Fauna (CTFB - Catálogo Taxonômico da Fauna do Brasil) through the collaboration of 100 coleopterists from all over the globe, we can build on Costa’s work and present an updated overview of the state of knowledge of the beetles from Brazil. There are currently 35,699 species in 4,958 genera and 116 families known to occur in the country, including representatives of all extant suborders and superfamilies. Our data show that the Brazilian beetle fauna is the richest on the planet, concentrating 9% of the world species diversity, with some estimates accounting to up to 15% of the global total. The most diverse family in numbers of genera is Cerambycidae (1,056 genera), while in number of species it is Chrysomelidae (6,079 species). Conotrachelus Dejean, 1835 (Curculionidae) is the most species-rich genus, with 570 species. The French entomologist Maurice Pic is the author who has contributed the most to the naming of species recorded from Brazil, with 1,794 valid names in 36 families, whereas the Brazilians Ubirajara R. Martins and Maria Helena M. Galileo are the only ones among the top-ten authors to have named species in the 21st century. Currently, approximately 144 new species of Brazilian beetles are described each year, and this average is projected to increase in the next decade to 180 species per year, or about one new Brazilian beetle every two days. 2000 ra Twentyfour Twenty four later CTFB Brasil 10 globe Costas s Brazil 35699 35 699 35,69 4958 4 958 4,95 11 country superfamilies planet 9 diversity 15 total 1,056 1056 1 056 (1,05 genera, , genera) 6,079 6079 6 079 (6,07 . species) Dejean 183 Curculionidae (Curculionidae speciesrich rich genus 57 1794 794 1,79 3 R M topten top ten st century Currently 14 year 18 days 200 3569 69 35,6 495 95 4,9 1,05 105 05 (1,0 6,07 607 07 (6,0 5 179 79 1,7 20 356 35, 49 4, 1,0 0 (1, 6,0 60 (6, 17 7 1, 2 (1 6, (6 (

https://doi.org/10.1590/s1984-4689.v41.e23072

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