Poly(amidoamine)-type dendrimers (PAMAM) were synthesized by divergent routes, and generations (G0.5, G1.0, G1.5, G2.0 and G2.5) along with hydroxylated half-generation polymers (G0.5-OH, G1.5-OH and G2.5-OH) were characterized by Fourier-transform infrared spectroscopy, thermogravimetric analysis and differential scanning calorimetry. Carbon dioxide (CO2) capture tests were performed using thermogravimetric analysis. Among the absorption temperatures tested, 60 °C was the most promising: 0.77, 1.08, and 1.14 mol CO2 L 1 for G0.5-OH, G1.5-OH and G2.5-OH, respectively, of CO2 and partial pressure of 45 kPa. This showed that dendrimers with larger molecular structures have more hydroxyl groups and consequently capture more CO2. However, at low partial pressures (< 2 kPa), CO2 solubility in PAMAM increased with temperature reduction, confirmed by Henry’s solubility constant (398.4 mol m3 kPa 1, in G2.5-OH at 40 °C). According to the thermodynamic properties of CO2 solubilization, the process was spontaneous (∆Gsol < 0) and exothermic (∆Hsol < 0). Polyamidoaminetype Poly amidoamine type (PAMAM routes G0.5, G05 G G0 5 (G0.5 G10 G1 0 G1.0 G15 G1.5 G20 G2 G2. G2.5 G25 halfgeneration half generation G0.5OH, G05OH GOH G0.5 OH, OH (G0.5-OH G1.5OH G15OH G2.5OH G25OH Fouriertransform Fourier transform spectroscopy calorimetry CO (CO2 tested 6 C promising 077 77 0.77 108 08 1.08 114 14 1.1 G0.5-OH G2.5OH, respectively 4 However ( kPa, , kPa) reduction Henrys Henry s 398.4 3984 398 (398. m °C. . °C) solubilization ∆Gsol Gsol ∆Hsol Hsol 0. (G0. G1. 5OH G0.5OH G0. (CO 07 7 0.7 10 1.0 11 1. 398. 39 (398 (G0 3 (39 (G (3

The objective of this work was to evaluate the total concentration and bioaccessible fractions of Ba, Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Pb, V and Zn in berry fruits and analyze the influence of different cultivars and growing conditions on the obtained results. The variations in bioaccessible concentrations were from 7.7-30, 17-29, 22-50, 1.8-96, 22-33 and 20-51% of the total concentration, for Ba, Cu, Fe, Mn, Pb and Zn, respectively. Copper showed greater bioaccessibility in blackberry and blueberry. For Fe, bioaccessibility was observed in all strawberries and blueberries and in some blackberries. Zinc presented higher bioaccessible fractions in strawberries. For V, only the sample Blackberry 124 showed bioaccessible concentration, (11% of the total concentration). Regarding the different forms of cultivation, the strawberries that received radiation from the red and white lamps presented a higher production of fruit compared to the other systems, however, in relation to the absorption of nutrients, a small variation was observed between the fruits. Ba Ca Cd Cr Cu Fe K Mg Mn results 7.730, 7730 7.7 30, 7 30 7.7-30 1729, 1729 17 29, 29 17-29 2250, 2250 22 50, 50 22-50 1.896, 1896 1.8 96, 1 8 96 1.8-96 2233 33 22-3 2051% 2051 20 51% 51 20-51 respectively blueberry blackberries 12 11% 11 (11 concentration. . concentration) cultivation systems however nutrients 730 7.730 773 77 7. 3 7.7-3 172 2 17-2 225 5 22-5 896 1.896 189 18 1. 9 1.8-9 223 22- 205 20-5 (1 73 7.73 7.7- 17- 89 1.89 1.8- 20- (

RESUMO Introdução: Doenças pulmonares são comuns em pacientes com doença renal em estágio terminal (DRET), dificultando o diagnóstico diferencial com COVID-19. Este estudo descreve achados de tomografia computadorizada de tórax (TC) em pacientes com DRET em terapia renal substitutiva (TRS) hospitalizados com suspeita de COVID-19. Métodos: Indivíduos maiores de 18 anos com DRET, encaminhados ao pronto-socorro com suspeita de COVID-19 foram incluídos. Dados clínicos e epidemiológicos foram extraídos de registros eletrônicos de saúde. A TC foi classificada como típica, indeterminada, atípica, negativa. Comparamos achados tomográficos de pacientes com COVID-19 positivos e negativos. Resultados: Recrutamos 109 pacientes (62,3% COVID-19-positivos) entre março e dezembro de 2020, idade média de 60 ± 12,5 anos, 43% mulheres. A etiologia mais comum da DRET foi diabetes. Tempo médio em diálise foi 36 meses, intervalo interquartil = 12–84. A lesão pulmonar mais comum foi opacidades em vidro fosco. O padrão típico de TC foi mais comum em pacientes com COVID-19 (40 (61%) vs. 0 (0%) em pacientes sem COVID-19, p < 0,001). Sensibilidade 60,61% (40/66), especificidade 100% (40/40). Valores preditivos positivos e negativos foram 100% e 62,3%, respectivamente. Padrão atípico de TC foi mais frequente em pacientes COVID-19-negativos (9 (14%) vs. 24 (56%) em COVID-19-positivos, p < 0,001), enquanto padrão indeterminado foi semelhante em ambos os grupos (13 (20%) vs. 6 (14%), p = 0,606), e padrão negativo foi mais comum em pacientes COVID-19-negativos (4 (6%) vs. 12 (28%), p = 0,002). Conclusões: Em pacientes com DRET em TRS hospitalizados, um padrão atípico de TC de tórax não pode excluir adequadamente o diagnóstico de COVID-19. Introdução , (DRET) COVID19. COVID19 COVID 19. 19 (TC (TRS Métodos 1 prontosocorro pronto socorro COVID-1 incluídos saúde típica indeterminada atípica negativa Resultados 10 62,3% 623 62 3 (62,3 COVID19positivos COVIDpositivos COVID-19-positivos 2020 125 5 12, 43 mulheres diabetes meses 1284 84 12–84 fosco 40 61% 61 (61% vs 0% (0% COVID19, 19, 0,001. 0001 0,001 . 001 0,001) 6061 60,61 40/66, 4066 40/66 66 (40/66) 100 40/40. 4040 40/40 (40/40) respectivamente COVID19negativos COVIDnegativos 9 ( 14% 14 (14% 2 56% 56 (56% COVID19positivos, positivos, 0,001, 13 (1 20% 20 (20% 14%, 0,606, 0606 0,606 606 0,606) 4 6% (6% 28%, 28 28% (28%) 0,002. 0002 0,002 002 0,002) Conclusões (DRET COVID1 COVID- 62,3 (62, 202 128 8 12–8 (61 (0 000 0,00 00 60,6 406 40/6 (40/66 404 40/4 (40/40 (14 (56 (20 060 0,60 (6 (28% 62, (62 12– 0,0 60, 40/ (40/6 (40/4 (5 (2 06 0,6 (28 0, (40/

ABSTRACT Introduction: Lung diseases are common in patients with end stage kidney disease (ESKD), making differential diagnosis with COVID-19 a challenge. This study describes pulmonary chest tomography (CT) findings in hospitalized ESKD patients on renal replacement therapy (RRT) with clinical suspicion of COVID-19. Methods: ESKD individuals referred to emergency department older than 18 years with clinical suspicion of COVID-19 were recruited. Epidemiological baseline clinical information was extracted from electronic health records. Pulmonary CT was classified as typical, indeterminate, atypical or negative. We then compared the CT findings of positive and negative COVID-19 patients. Results: We recruited 109 patients (62.3% COVID-19-positive) between March and December 2020, mean age 60 ± 12.5 years, 43% female. The most common etiology of ESKD was diabetes. Median time on dialysis was 36 months, interquartile range = 12–84. The most common pulmonary lesion on CT was ground glass opacities. Typical CT pattern was more common in COVID-19 patients (40 (61%) vs 0 (0%) in non-COVID-19 patients, p < 0.001). Sensitivity was 60.61% (40/66) and specificity was 100% (40/40). Positive predictive value and negative predictive value were 100% and 62.3%, respectively. Atypical CT pattern was more frequent in COVID-19-negative patients (9 (14%) vs 24 (56%) in COVID-19-positive, p < 0.001), while the indeterminate pattern was similar in both groups (13 (20%) vs 6 (14%), p = 0.606), and negative pattern was more common in COVID-19-negative patients (4 (6%) vs 12 (28%), p = 0.002). Conclusions: In hospitalized ESKD patients on RRT, atypical chest CT pattern cannot adequately rule out the diagnosis of COVID-19. Introduction ESKD, , (ESKD) COVID19 COVID 19 COVID-1 challenge (CT RRT (RRT COVID19. 19. Methods 1 records typical Results 10 62.3% 623 62 3 (62.3 COVID19positive COVIDpositive COVID-19-positive 2020 125 5 12. 43 female diabetes months 1284 84 12–84 opacities 40 61% 61 (61% 0% (0% nonCOVID19 nonCOVID non non-COVID-1 0.001. 0001 0.001 . 001 0.001) 6061 60.61 40/66 4066 66 (40/66 100 40/40. 4040 40/40 (40/40) respectively COVID19negative COVIDnegative 9 ( 14% 14 (14% 2 56% 56 (56% COVID19positive, positive, 0.001, 13 (1 20% 20 (20% 14%, 0.606, 0606 0.606 606 0.606) 4 6% (6% 28%, 28 28% (28%) 0.002. 0002 0.002 002 0.002) Conclusions (ESKD COVID1 COVID- 62.3 (62. 202 128 8 12–8 (61 (0 nonCOVID1 non-COVID- 000 0.00 00 60.6 40/6 406 (40/6 404 40/4 (40/40 (14 (56 (20 060 0.60 (6 (28% 62. (62 12– non-COVID 0.0 60. 40/ (40/ (40/4 (5 (2 06 0.6 (28 0.

ABSTRACT The goal of this study was to estimate the prevalence of environmental and occupational exposure to pesticides according to sociodemographic factors among cancer patients. It is a cross-sectional study with cancer patients in the state of Mato Grosso. The prevalence of environmental and occupational exposure to pesticides was calculated as to the variables gender, age, macro-region, and education. Pesticide use per agricultural crops in liters was estimated, and a thematic map was constructed following the macro-region of the agricultural economy. Of the 998 patients, most were female (54.9%), aged between 50 and 69 years old (50.1%), had less than eight years of schooling (60.7%), and resided in the South-Central macro-region (55.4%). Regarding environmental and occupational exposure, 53.1% of the patients live or have lived in a municipality with agricultural plantations; 17.4% lived near crops; 43.4% worked in agriculture, livestock, or extractivism; and 22.9% worked or work directly with pesticides. Environmental and occupational exposure was higher in males, in the older age groups, schooling from 0 to 4 years, and in the macro-regions with higher pesticide use. The study concluded that environmental and occupational exposure among cancer patients is associated to sociodemographic characteristics and macro-regions of the agricultural economy.

RESUMO O objetivo deste estudo foi estimar a prevalência de exposição ambiental e ocupacional aos agrotóxicos conforme fatores sociodemográficos entre pacientes com câncer. Trata-se de um estudo observacional de delineamento transversal com pacientes com câncer do estado de Mato Grosso. Foi calculada a prevalência de exposição ambiental e ocupacional aos agrotóxicos conforme as variáveis sexo, faixa etária, região e escolaridade. Foram estimados o uso de agrotóxicos por culturas agrícolas em litros e construído mapa temático segundo a macrorregião de economia agropecuária. Dos 998 pacientes, a maioria era do sexo feminino (54,9%), tinha entre 50 e 69 anos (50,1%), possuía menos de oito anos de escolaridade (60,7%) e residiam na macrorregião Centro-Sul (55,4%). Em relação à exposição ambiental e ocupacional, 53,1% dos pacientes moram ou moraram em município com plantação agrícola, 17,4% residiam próximo à lavoura, 43,4% trabalharam na agricultura, pecuária ou extrativismo e 22,9% trabalharam ou trabalham diretamente com agrotóxicos. A exposição ambiental e ocupacional foi maior no sexo masculino, nas faixas etárias mais elevadas, escolaridade de 0 a 4 anos e nas macrorregiões de maior uso de agrotóxicos. Conclui-se que a exposição ambiental e ocupacional entre pacientes com câncer se associou as características sociodemográficas e macrorregiões de economia agropecuária.

ABSTRACT The goal of this study was to estimate the prevalence of environmental and occupational exposure to pesticides according to sociodemographic factors among cancer patients. It is a cross-sectional study with cancer patients in the state of Mato Grosso. The prevalence of environmental and occupational exposure to pesticides was calculated as to the variables gender, age, macro-region, and education. Pesticide use per agricultural crops in liters was estimated, and a thematic map was constructed following the macro-region of the agricultural economy. Of the 998 patients, most were female (54.9%), aged between 50 and 69 years old (50.1%), had less than eight years of schooling (60.7%), and resided in the South-Central macro-region (55.4%). Regarding environmental and occupational exposure, 53.1% of the patients live or have lived in a municipality with agricultural plantations; 17.4% lived near crops; 43.4% worked in agriculture, livestock, or extractivism; and 22.9% worked or work directly with pesticides. Environmental and occupational exposure was higher in males, in the older age groups, schooling from 0 to 4 years, and in the macro-regions with higher pesticide use. The study concluded that environmental and occupational exposure among cancer patients is associated to sociodemographic characteristics and macro-regions of the agricultural economy. crosssectional cross sectional Grosso gender macroregion, macroregion macro region, region education estimated economy 99 54.9%, 549 54.9% , 54 9 (54.9%) 5 6 50.1%, 501 50.1% 1 (50.1%) 60.7%, 607 60.7% 60 7 (60.7%) SouthCentral South Central 55.4%. 554 55.4% . 55 (55.4%) 531 53 53.1 plantations 174 17 17.4 434 43 43.4 agriculture livestock extractivism 229 22 22.9 males groups macroregions regions 54.9 (54.9% 50.1 (50.1% 60.7 (60.7% 55.4 (55.4% 53. 17. 43. 2 22. 54. (54.9 50. (50.1 60. (60.7 55. (55.4 (54. (50. (60. (55. (54 (50 (60 (55 (5 (6 (

RESUMO O objetivo deste estudo foi estimar a prevalência de exposição ambiental e ocupacional aos agrotóxicos conforme fatores sociodemográficos entre pacientes com câncer. Trata-se de um estudo observacional de delineamento transversal com pacientes com câncer do estado de Mato Grosso. Foi calculada a prevalência de exposição ambiental e ocupacional aos agrotóxicos conforme as variáveis sexo, faixa etária, região e escolaridade. Foram estimados o uso de agrotóxicos por culturas agrícolas em litros e construído mapa temático segundo a macrorregião de economia agropecuária. Dos 998 pacientes, a maioria era do sexo feminino (54,9%), tinha entre 50 e 69 anos (50,1%), possuía menos de oito anos de escolaridade (60,7%) e residiam na macrorregião Centro-Sul (55,4%). Em relação à exposição ambiental e ocupacional, 53,1% dos pacientes moram ou moraram em município com plantação agrícola, 17,4% residiam próximo à lavoura, 43,4% trabalharam na agricultura, pecuária ou extrativismo e 22,9% trabalharam ou trabalham diretamente com agrotóxicos. A exposição ambiental e ocupacional foi maior no sexo masculino, nas faixas etárias mais elevadas, escolaridade de 0 a 4 anos e nas macrorregiões de maior uso de agrotóxicos. Conclui-se que a exposição ambiental e ocupacional entre pacientes com câncer se associou as características sociodemográficas e macrorregiões de economia agropecuária. Tratase Trata Grosso etária agropecuária 99 54,9%, 549 54,9% , 54 9 (54,9%) 5 6 50,1%, 501 50,1% 1 (50,1%) 60,7% 607 60 7 (60,7% CentroSul Centro Sul 55,4%. 554 55,4% . 55 (55,4%) 531 53 53,1 agrícola 174 17 17,4 lavoura 434 43 43,4 agricultura 229 22 22,9 masculino elevadas Concluise Conclui 54,9 (54,9% 50,1 (50,1% 60,7 (60,7 55,4 (55,4% 53, 17, 43, 2 22, 54, (54,9 50, (50,1 60, (60, 55, (55,4 (54, (50, (60 (55, (54 (50 (6 (55 (5 (

Abstract Radicular cysts result from an inflammatory process associated with teeth with pulp necrosis. The initial therapy is the endodontic treatment. However, if it fails, other treatment alternatives should be considered. Among them are some types of endodontic surgery that should be indicated according to the diagnosis of the tooth involved. Another technique for treating cysts is decompression, which can be used for the reduction or complete regression of the lesion and the preservation of adjacent noble structures. This case report, with a follow-up of two years, aims to present the therapy of a radicular cyst in close association with the mandibular canal through endodontic surgery and decompression of the lesion, as an alternative method to preserve the innervation of the inferior alveolar nerve.

Resumo O cisto radicular é um cisto de origem odontogénica causado por um processo inflamatório associado a dentes com diagnóstico de necrose pulpar. São os cistos mais comuns dos maxilares. A terapia inicial de eleição é o tratamento endodôntico do dente acometido. Contudo, em casos de insucesso, outras alternativas de tratamento devem ser consideradas. Entre as alternativas existem alguns tipos de cirurgia paraendodôntica que devem ser indicados de acordo com o diagnóstico do dente envolvido. Outra técnica para tratamento dos cistos é a descompressão, que pode ser utilizada para redução ou regressão completa da lesão e para conservação de estruturas nobres adjacentes. Esse relato de caso, com acompanhamento de dois anos, tem como objetivo apresentar a terapia de um cisto radicular em íntimo contato com o canal mandibular, por meio da cirurgia paraendodôntica e descompressão da lesão como método alternativo para preservação da inervação do nervo alveolar inferior.

Abstract The entertainment industry is featured by discursive productions of ideological nature. Accordingly, different music genres work as identity vectors; thus, it is possible perceiving the representation of male individuals as the dominant gender in some of them. Bregafunk music stands out among these genres, since its music videos highlight straight and virile men, by showing women, LGBTQIAPN+ individuals and fat bodies in a stigmatized way. Based on the Foucauldian theory, the current study addresses the subjectivity “abnormalization” process carried out by another socially dominant subjectivity as way to defend and maintain its position. In order to do so, the current research presents the following investigative question: how do bregafunk music video productions represent alterities to male subjectivity? In total, 777 bregafunk music videos posted on YouTube between September 2012 and September 2020 were herein investigated, based on the foucauldian discourse analysis, in order to answer this question. Results have evidenced the dominant discourse of “male bregafunk music artists”, which is anchored in a strategy focused on perpetuating stereotypes and chauvinism. Thus, it was possible concluding that this subjectivity is a variation of the alpha male, who resorts to his cultural repertoire and social context to consolidate himself as the dominant identity by subjugating other identities through a double move comprising self-affirmation and denial of others. In addition, it was possible inferring that targeting women, LGBTQIAPN+ and fat individuals may be a defense strategy to address the growing political space gained by these identities in recent decades. nature Accordingly vectors thus them men women LGBTQIAPN theory abnormalization “abnormalization position so question total 77 201 202 investigated analysis artists, artists , artists” chauvinism Thus selfaffirmation self affirmation others addition decades 7 20 2

Resumo A indústria do entretenimento é caracterizada por produções discursivas de natureza ideológica. Desta maneira, diferentes gêneros musicais atuam como vetores de identidade; assim, é possível perceber a representação de homens como o gênero dominante em alguns. O Bregafunk se destaca entre estes gêneros, uma vez que seus videoclipes evidenciam homens héteros e viris ao mostrar mulheres, pessoas LGBTQIAPN+ e pessoas gordas de maneira estigmatizada. Baseado na teoria foucaultiana, o presente estudo aborda o processo de “anormalização” de uma subjetividade, realizado por outra subjetividade socialmente dominante como forma de defender e manter sua posição. Para realizar este processo, este trabalho apresenta a seguinte pergunta de pesquisa: como as produções de videoclipes do bregafunk representam alteridades da subjetividade masculina? No total, 777 videoclipes de bregafunk postados no YouTube entre setembro de 2012 e setembro de 2020 foram investigados a partir da análise de discurso foucaultiana a fim de responder a esta questão. Resultados evidenciaram o discurso dominante do “artista macho do bregafunk”, ancorado em uma estratégia que foca na perpetuação de estereótipos e do machismo. Assim, foi possível concluir que esta subjetividade é uma variação do macho alfa, que se baseia no repertório cultural e contexto social para se consolidar como a identidade dominante ao subjugar outras identidades em um movimento duplo consistente de uma autoafirmação e uma negação do outro. Além disso, foi possível inferir que ter como alvo mulheres, pessoas LGBTQIAPN+ e pessoas gordas pode ser uma estratégia de defesa contra o crescimento do poder político destes grupos nas últimas décadas. ideológica assim alguns mulheres LGBTQIAPN estigmatizada anormalização “anormalização posição pesquisa masculina total 77 201 202 questão artista bregafunk, , bregafunk” machismo Assim alfa outro disso décadas 7 20 2

ABSTRACT: Nowadays, alternative methods that do not use formaldehyde to preserve cadavers must be used due to this substance’s toxicity. Synthetic models are a training option for teaching, but cost makes their use unviable in most underdeveloped countries. The present study’s main objective was to develop a model for education and researching thorax radiology in cadavers of chemically prepared dogs. Megaesophagus, pleural effusion, pneumothorax, and bronchography, as well as pulmonary insufflation, were simulated in 32 dogs cadavers, which received 150 mL/kg of pure ethyl alcohol solution with 5% glycerin followed by injection of 120 mL/kg of a solution containing 20% sodium chloride, 1% sodium nitrite and 1% sodium nitrate; they were kept refrigerated between 2 to 6 °C, for 30, 60, 90 or 120 days (G30, G60, G90, G120). There was no contamination, putrid odor, or subcutaneous emphysema. The pulmonary insufflation was kept, and the color and the consistency were similar to a fresh corpse after 120 days of conservation. It was possible to perform radiographic procedures, and almost all affections could be greatly mimicked. Megaesophagus and bronchography were easily simulated. Pneumothorax was the most challenging condition to be reproduced, especially in cadavers with some liquid in the thorax. The alcoholic and curing salt solutions are an embalming alternative with low financial and environmental costs and proved to preserve corpses. ABSTRACT Nowadays substances substance s toxicity teaching countries studys study effusion pneumothorax 3 15 mLkg mL kg 5 12 20 chloride 1 nitrate C °C 30 60 9 G30, G30 G (G30 G60 G90 G120. G120 . G120) contamination odor emphysema conservation procedures mimicked reproduced corpses G3 (G3 G6 G9 G12 (G G1

RESUMO: Nos dias atuais, métodos alternativos e que não utilizem o formaldeído para conservação de cadáveres devem ser empregados, devido à toxicidade desse agente. Modelos sintéticos são opção de treinamento para o ensino, mas geralmente o preço inviabiliza seu uso na maioria dos países subdesenvolvidos. O objetivo do presente trabalho foi desenvolver um modelo visando ao ensino e pesquisa da radiologia torácica em cadáveres de cães quimicamente preparados. Foram simulados megaesôfago, efusão pleural, pneumotórax e broncografia, além de insuflação pulmonar, em 32 cadáveres de cães, que receberam 150 mL/kg de solução de álcool etílico puro com 5% de glicerina seguido de injeção de 120 mL/kg de solução contendo 20% de cloreto de sódio, 1% de nitrito de sódio e 1% de nitrato de sódio, mantidos sob refrigeração entre 2 e 6 graus, por 30, 60, 90 ou 120 dias (G30, G60, G90, G120). Não houve contaminação, odor pútrido ou enfisema subcutâneo. A insuflação pulmonar foi mantida, e a cor e a consistência foram semelhantes a um cadáver fresco após 120 dias de conservação. Em todos os grupos foi possível realizar os procedimentos radiográficos e quase todas afecções puderam ser grandemente mimetizadas. O megaesôfago e a broncografia foram facilmente simuladas. O pneumotórax foi a afecção mais difícil de ser simulada principalmente nos cadáveres com um pouco de líquido na cavidade torácica. A solução alcoólica e de sal de cura são uma alternativa de embalsamamento com baixo custo financeiro e ambiental e comprovadamente conservam cadáveres. RESUMO atuais empregados agente subdesenvolvidos preparados pleural 3 15 mLkg mL kg 5 12 20 1 graus 30 60 9 G30, G30 G (G30 G60 G90 G120. G120 . G120) contaminação subcutâneo mantida mimetizadas simuladas G3 (G3 G6 G9 G12 (G G1

Abstract In this study, videothermometry’s application in detecting mammary tumors in dogs is explored in-depth. The research hypothesizes that this technique can effectively identify cancerous tissues during surgery by analyzing thermal patterns. The methodology involved comparing thermal imaging results from dogs with palpable mammary nodules against a control group, focusing on capturing real-time thermal patterns. Results were significant, showing distinct thermal patterns in carcinomas. This indicates videothermometry’s capability in accurately identifying micro metastases and differentiating between neoplastic and non-neoplastic changes. The study concludes that videothermometry has considerable potential in enhancing surgical precision, especially in tumor resection and safety margin definition, but emphasizes the need for further research to thoroughly understand the thermal signatures of various mammary tumors in dogs. videothermometrys s indepth. indepth depth. depth in-depth group realtime real time significant carcinomas nonneoplastic non changes precision definition

ABSTRACT This case report identified paracentral acute middle maculopathy as the cause of severe and irreversible vision loss after cataract surgery. Cataract surgeons should be aware of known risk factors for the development of paracentral acute middle maculopathy. In those patients, extra care regarding anesthesia, intraocular pressure, and some other aspects of cataract surgery must be taken. Paracentral acute middle maculopathy is currently understood as a clinical sign evident on spectral-domain optical coherence tomography, and it is probably evidence of deep ischemic insult to the retina. It should be a differential diagnosis in cases of marked low vision acuity associated with no fundus abnormalities in the immediate postoperative period, as demonstrated in the presented case. patients anesthesia pressure taken spectraldomain spectral domain tomography retina period

RESUMO O presente relato de caso identificou a maculopatia média aguda paracentral como a causa de baixa de acuidade visual severa e irreversível após cirurgia de catarata. Existem fatores de risco bem estabelecidos para o desenvolvimento da maculopatia média aguda paracentral que devem ser conhecidos pelos cirurgiões de catarata. Nesse contexto cirúrgico, precauções extras no tocante a procedimentos anestésicos, pressão intraocular e alguns outros aspectos da cirurgia devem ser consideradas. A maculopatia média aguda paracentral é descrita como um sinal clínico observado no exame de tomografia de coerência óptica por domínio espectral e se trata, provavelmente, da evidência de um evento isquêmico no tecido vascular retiniano. Esse diagnóstico deve ser cogitado nos casos de perda de acuidade visual súbita no pós-operatório imediato associada com exame fundoscópico normal, como evidenciado no caso apresentado. catarata cirúrgico anestésicos consideradas trata provavelmente retiniano pósoperatório pós operatório normal apresentado

Abstract Objectives The emergence of the coronavirus disease 2019 (COVID-19) pandemic and subsequent lockdowns and social distancing measures adopted worldwide raised questions about the possible health effects of human social isolation. Methods We conducted a systematic review on PubMed, Scopus, and Embase electronic databases using terms related to human social isolation – defined as the isolation of an individual from regular routines and usual social contact – and psychological stress, searching for simulated or naturalistic isolation environments. We present the main results, as well as the validity and limitations of each model. PROSPERO registry number: CRD42021241880. Results Despite the diversity of contexts reviewed, some outcomes almost ubiquitously relate to psychological stress, i.e., longer periods, expectation of a longer period, confinement, lack of social interaction, and support. Based on the results, and considering that most studies were not designed for the purpose of understanding isolation itself, we propose a group of recommendations for future experimental or naturalistic research on the topic. Conclusion Evidence on the impact of different situations in which individuals are subjected to social isolation can assist in development of directed preventive strategies to support people under similar circumstances. Such strategies might increase the general public’s compliance with social distancing as a non-pharmacological intervention for emerging infectious diseases. 201 COVID19 COVID 19 (COVID-19 PubMed Scopus stress environments results model number CRD42021241880 CRD reviewed ie i e i.e. periods period confinement interaction itself topic circumstances publics public s nonpharmacological non pharmacological diseases 20 COVID1 1 (COVID-1 CRD4202124188 i.e 2 (COVID- CRD420212418 (COVID CRD42021241 CRD4202124 CRD420212 CRD42021 CRD4202 CRD420 CRD42 CRD4

Resumen Objetivo identificar el perfil de niños y adolescentes dependientes de tecnología atendidos en un hospital de referência pediátrica del sur del país. Método estudio descriptivo con enfoque cuantitativo. La recolección de datos ocurrió através del análisis de las historias clínicas, desde enero de 2016 hasta diciembre de 2019, almacenadas en una hoja de cálculo de Microsoft Excel para el análisis estadístico descriptivo. El proyecto fue aprobado por el Comité de Ética bajo el parecer 5.115.194. Resultados predominaron varones (50,8%), en período de desarrollo preescolar (30,8%), la región más frecuentada de la Gran Florianópolis (60,1%). Los diagnósticos más frecuentes estuvieron relacionados con prematuridad/el período neonatal, anomalías congénitas/defectos genéticos, enfermedades neurológicas y/o neuromusculares, correspondiendo al 37%, 33,2% y 18,5%, respectivamente. Los dispositivos tecnológicos más utilizados fueron la gastrostomía (56,3%) y la traqueotomía (36,6%). El uso de medicación continua ocurrió en el 93,4% y el 49,2% utilizó cuatro o más medicamentos. Las madres fueron las principales cuidadoras en 80,9% de los casos, ocurriendo 31 óbitos en el período. Conclusión e implicación para la práctica este grupo tiene una alta demanda de atención debido al diagnóstico principal, dispositivos tecnológicos, medicamentos y posibles complicaciones. Identificar el perfil de niños y adolescentes dependientes de tecnología contribuye a aumentar la visibilidad de una población en constante crecimiento y, por lo tanto, calificar la asistencia, de acuerdo com sus especificidades y reales necesidades. país cuantitativo clínicas 201 2019 5115194 5 115 194 5.115.194 50,8%, 508 50,8% , 50 8 (50,8%) 30,8%, 308 30,8% 30 (30,8%) 60,1%. 601 60,1% . 60 1 (60,1%) prematuridadel prematuridad neonatal congénitasdefectos congénitas defectos genéticos yo neuromusculares 37 37% 332 33 2 33,2 185 18 18,5% respectivamente 56,3% 563 56 3 (56,3% 36,6%. 366 36,6% 36 6 (36,6%) 934 93 4 93,4 492 49 49,2 809 80 9 80,9 casos principal complicaciones tanto asistencia necesidades 20 511519 11 19 5.115.19 50,8 (50,8% 30,8 (30,8% 60,1 (60,1% 33, 18,5 56,3 (56,3 36,6 (36,6% 93, 49, 80, 51151 5.115.1 50, (50,8 30, (30,8 60, (60,1 18, 56, (56, 36, (36,6 5115 5.115. (50, (30, (60, (56 (36, 511 5.115 (50 (30 (60 (5 (36 51 5.11 (3 (6 ( 5.1 5.

Abstract Objective to identify the profile of technology-dependent children and adolescents at a pediatric referral hospital in southern Brazil. Method a descriptive study with a quantitative approach. Data was collected by analyzing medical records between January 2016 and December 2019 and stored in a Microsoft Excel spreadsheet for descriptive statistical analysis. The project was approved by the Ethics Committee under protocol number 5.115.194. Results: The prevalence was male (50.8%), pre-school age (30.8%), from Greater Florianópolis (60.1%). The most frequent diagnoses were related to prematurity/neonatal period, congenital anomalies/genetic defects, and neurological and/or neuromuscular diseases, corresponding to 37%, 33.2%, and 18.5%. The most commonly used technological devices were gastrostomy (56.3%) and tracheostomy (36.6%). 93.4% used continuous medication and 49.2% used four or more medications. Mothers were the main caregivers (80.9%). There were 31 deaths during the period. Conclusion and implications for practice this group has a high demand for care due to the main diagnosis, technological devices, medications, and possible complications. Identifying the profile of technology-dependent children and adolescents has helped to increase the visibility of a population that is constantly growing and thus provides comprehensive care according to their specific needs. technologydependent technology dependent Brazil approach 201 analysis 5115194 5 115 194 5.115.194 Results 50.8%, 508 50.8% , 50 8 (50.8%) preschool pre school 30.8%, 308 30.8% 30 (30.8%) 60.1%. 601 60.1% . 60 1 (60.1%) prematurityneonatal prematurity neonatal period anomaliesgenetic anomalies genetic defects andor diseases 37 37% 332 33 2 33.2% 185 18 18.5% 56.3% 563 56 3 (56.3% 36.6%. 366 36.6% 36 6 (36.6%) 934 93 4 93.4 492 49 49.2 medications 80.9%. 809 80.9% 80 9 (80.9%) diagnosis complications needs 20 511519 11 19 5.115.19 50.8 (50.8% 30.8 (30.8% 60.1 (60.1% 33.2 18.5 56.3 (56.3 36.6 (36.6% 93. 49. 80.9 (80.9% 51151 5.115.1 50. (50.8 30. (30.8 60. (60.1 33. 18. 56. (56. 36. (36.6 80. (80.9 5115 5.115. (50. (30. (60. (56 (36. (80. 511 5.115 (50 (30 (60 (5 (36 (80 51 5.11 (3 (6 ( (8 5.1 5.

Resumo Objetivo identificar o perfil de crianças e adolescentes dependentes de tecnologia de um hospital de referência pediátrica do sul do país. Método estudo descritivo, com abordagem quantitativa. A coleta de dados ocorreu por meio da análise de prontuários, entre janeiro de 2016 e dezembro de 2019, armazenados em planilha Microsoft Excel para a análise estatística descritiva. Um projeto aprovado pelo Comitê de Ética sob o parecer 5.115.194. Resultados prevaleceu o sexo masculino (50,8%), em idade pré-escolar (30,8%), proveniente da Grande Florianópolis (60,1%). Os diagnósticos mais frequentes foram relacionados à prematuridade/período neonatal, anomalias congênitas/defeitos genéticos, doenças neurológicas e/ou neuromusculares, correspondendo a 37%, 33,2% e 18,5%. Os dispositivos tecnológicos mais utilizados foram gastrostomia (56,3%) e traqueostomia (36,6%). A utilização de medicamentos contínuos se deu em 93,4% e 49,2% utilizavam quatro ou mais medicamentos. As mães foram as principais cuidadoras (80,9%). Ocorreram 31 óbitos no período. Conclusão e implicação para a prática este grupo apresenta grande demanda de cuidados decorrentes do diagnóstico principal, dos dispositivos tecnológicos, das medicações e das possíveis complicações. A identificação do perfil das crianças e adolescentes dependentes de tecnologia contribuiu para ampliar a visibilidade de uma população que está em constante crescimento e, assim, prestar uma assistência integral, de acordo com suas especificidades e reais necessidades. país descritivo quantitativa prontuários 201 2019 descritiva 5115194 5 115 194 5.115.194 50,8%, 508 50,8% , 50 8 (50,8%) préescolar pré escolar 30,8%, 308 30,8% 30 (30,8%) 60,1%. 601 60,1% . 60 1 (60,1%) prematuridadeperíodo prematuridade período neonatal congênitasdefeitos congênitas defeitos genéticos eou neuromusculares 37 37% 332 33 2 33,2 185 18 18,5% 56,3% 563 56 3 (56,3% 36,6%. 366 36,6% 36 6 (36,6%) 934 93 4 93,4 492 49 49,2 80,9%. 809 80,9% 80 9 (80,9%) principal complicações assim integral necessidades 20 511519 11 19 5.115.19 50,8 (50,8% 30,8 (30,8% 60,1 (60,1% 33, 18,5 56,3 (56,3 36,6 (36,6% 93, 49, 80,9 (80,9% 51151 5.115.1 50, (50,8 30, (30,8 60, (60,1 18, 56, (56, 36, (36,6 80, (80,9 5115 5.115. (50, (30, (60, (56 (36, (80, 511 5.115 (50 (30 (60 (5 (36 (80 51 5.11 (3 (6 ( (8 5.1 5.

Abstract This paper discusses the potential of gamification as a tool for teaching and learning in geotechnical engineering. Gamification involves incorporating elements of gameplay such as challenges, rewards, competition, and cooperation into teaching and learning environments to make the process more interactive and engaging. Although gamification is widely used in many fields, it is still relatively new in geotechnical engineering. This paper presents the ‘Soil Character’ board game developed by the GeoFUN group as an example of successful gamification in geotechnical engineering education. The game focuses on basic soil characterization, including soil classification systems, index properties, and geotechnical characterization tests such as sieving, sedimentation, and Atterberg limits. The paper provides background information on the development of the game, and a description of the game components. The online Portuguese version of the game was tested with eight civil engineering undergraduate students who had successfully undertaken the introductory soil mechanics module. Student’s satisfaction in terms of game design, rules, and gameplay was measured via a questionnaire. Results of the questionnaires showed that the game was well evaluated in all aspects. Student volunteers reported that they felt very motivated, and that they wished they had been able to play the game when they were learning the topic. Thus, results presented in this paper suggest that gamification has the potential to make geotechnical engineering education more interactive and engaging. Exploring the effectiveness of the game in various contexts and with diverse student populations constitutes a key direction for our future research. challenges rewards competition engaging fields Soil Character systems properties sieving sedimentation limits components module Students s design rules questionnaire aspects motivated topic Thus research

Abstract This study aimed to identify and characterize the antimicrobial susceptibility profile of bacteria found in primary endodontic infections in the teeth of patients treated at the Dental Clinic of the University of Ribeirão Preto, São Paulo, Brazil. From September to December 2019, samples were obtained from 21 patients with primary endodontic infections. The collections were carried out in triplicate using paper cones placed close to the total length of the root canal. Bacterial isolation was performed in Brain Heart Infusion agar, Blood agar, and other selective culture media cultured at 37°C for up to 48 h under aerobiosis and microaerophilic conditions. The bacterial species were identified using the Vitek 2 automated system. The disk diffusion method on agar Müeller–Hinton was used to assess antimicrobial susceptibility with the recommended antimicrobials for each identified bacterial species. A total of 49 antibiotics were evaluated. Fifteen of the 21 samples collected showed bacterial growth, and 17 bacterial isolates were found. There were 10 different bacterial species identified: Enterococcus faecalis (four isolates), Streptococcus mitis/oralis (three isolates), Streptococcus anginosus (three isolates) being the most common, followed by Staphylococcus epidermidis, Enterococcus faecium, Streptococcus constellatus, Streptococcus alactolyticus, Enterobacter cloacae, Klebsiella variicola, and Providencia rettgeri (one isolate of each species). The analysis demonstrated significant susceptibility to most of the tested antibiotics. However, some Enterococcus isolates resisted the antibiotic’s erythromycin, ciprofloxacin, and tetracycline. A Staphylococcus epidermidis isolate was characterized as multidrug-resistant. Five Streptococcus isolates were non-susceptible to all antibiotics tested. Preto Paulo Brazil 2019 canal 37C C 37 4 conditions system MüellerHinton Müeller Hinton evaluated growth 1 four isolates, , mitisoralis mitis oralis three common faecium constellatus alactolyticus cloacae variicola one . species) However antibiotic s erythromycin ciprofloxacin tetracycline multidrugresistant. multidrugresistant multidrug resistant. resistant multidrug-resistant nonsusceptible non susceptible 201 3 20

ABSTRACT Physical properties of the Technosols formed by the tailings deposition may constitute a physical barrier that limits water movement and plant development due to the properties received from those sediments. This study aimed to evaluate the physical quality of the Technosols formed by the deposition of sediments displaced by the Fundão Dam failure, Mariana, Minas Gerais State, Brazil, based on the evaluation of physical properties and Load Bearing Capacity Models (LBCM). For that, three areas under different vegetation types were selected: eucalyptus (Euc), forest with human-assisted revegetation (RF), and forest with native vegetation (NF). Three sampling subareas were demarcated in each area: non-impacted areas (Ni), and Technosols formed in directly impacted areas (Di), and partially impacted areas (Pi). Undisturbed samples were collected in two layers and subjected to the uniaxial compression test after equilibration at five matric potentials. Soil compression curves and LBCM were determined. Soil bulk density (BD), total porosity (TP), organic matter (OM), granulometry, and particle density (PD) were also determined. Clay content was less significant, and the silt and very fine sand content was significantly higher in the Technosols, generating an increase in BD and reduction in TP. Technosols generally exhibited greater load-bearing capacity due to higher pre-consolidation pressure values attained by these soils due to the lower clay and OM contents. High resistance of these soils is one limitation for revegetation of the areas evaluated, being necessary management practices to improve physical properties of the Technosols. failure Mariana State Brazil LBCM. . (LBCM) selected Euc, Euc , (Euc) humanassisted human assisted RF, RF (RF) NF. NF (NF) area nonimpacted non Ni, Ni (Ni) Di, Di (Di) Pi. Pi (Pi) potentials determined BD, (BD) TP, TP (TP) OM, (OM) granulometry PD (PD significant loadbearing load bearing preconsolidation pre consolidation contents evaluated (LBCM (Euc (RF (NF (Ni (Di (Pi (BD (TP (OM