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au:Souza, Fabiana Mendes de

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Cross-cultural adaptation and validation of Sarcopenia and Quality of Life (SarQoL) in Brazil
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Orlandi, Fabiana de Souza

; Nunes, Juliana Duarte

; Santos, Diana Gabriela Mendes dos

; Gratão, Aline Cristina Martins

; Zazzetta, Marisa Silvana

Sao Paulo Medical Journal

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feb 2023, Volume 141 N. 1 Pages 30 - 35

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Sarcopenia is defined as a slow, progressive, and apparently inevitable process of involuntary loss of muscle mass, strength, and quality, which occurs with advancing age. It is widely accepted that sarcopenia can directly affect quality of life. OBJECTIVE: Translate, adapt and validate the “Sarcopenia and Quality of Life” instrument (SarQoL) to the Brazilian context. DESIGN AND SETTINGS: Translation, cross-cultural adaptation, and validation study carried out at the Federal University of São Carlos, São Carlos, São Paulo, Brazil. METHODS: The population consisted of 221 older adult participants. The steps recommended by the guidelines from the authors of the original instrument were followed sequentially: initial translation, synthesis of translations, backward translation, evaluation by a panel of judges, pre-test, and analysis of psychometric properties. The translation and adaptation process was conducted as recommended. RESULTS: Two hundred and twenty-one participants took part in the step analysis of the psychometric properties of SarQoL, in which 55 presented sarcopenia. Cronbach's alpha coefficient of the total SarQoL questionnaire was 0.976, indicating excellent internal consistency. Excellent agreements between the test and retest with an Interclass Correlation Coefficient (ICC) of 0.983 (95% confidence interval: 0.901–0.996) were observed in the SarQoL domains. The domains of Short-Form 36 and EuroQoL 5-dimension showed significant correlation, from moderate to strong magnitude, with SarQoL total score, indicating convergent validity. CONCLUSION: The Brazilian version of SarQoL presented evidence of reliability and validity.

https://doi.org/10.1590/1516-3180.2021.0968.r1.07042022

Health-related quality of life in children with cerebral palsy associated with congenital Zika infection
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Marques, Fernanda Jordão Pinto

; Carvalho, Alessandra Lemos de

; Borigato, Eliana Valverde Magro

; Oliveira, Luiz Felipe Vieira de

; Duarte, Lenamaris Mendes Rocha

; Silva, Adriana Goncalves da

; Amarante, Claret Luiz Dias

; Pereira, Laura Jácome de Melo

; Tavares, Elise Ferreira

; Costa, Lilian Gleice de Sena da

; Alcântara, Carolina Alves Rezende

; Salinas, Andrea Nakamura

; Pinto, Fernanda de Lourdes da Cunha

; Alcântara, Gerliane Carvalho de

; Utsch, Fabiana

; Silva, Cinthia Ramos Diniz

; Reis, Dirlene Araujo dos

; Bessa, Wilerson Marques

; Dutra, Rafaela Christine

; Ventura, Paloma

; Oliveira, Tatiana Souza

Revista Paulista de Pediatria

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2023, Volume 41 elocation e2022016

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective: To describe the health-related quality of life (QOL) in children with cerebral palsy (CP) associated with congenital Zika infection. Methods: Cross-sectional study of a consecutive series of children, followed in a referral multicentric rehabilitation network in Brazil. We invited the caregivers to respond to the Brazilian version of the Caregiver Priorities & Child Health Index of Life with Disabilities (CPCHILDTM) questionnaire. Statistical analysis was performed with the Statistical Package for the Social Sciences (SPSS) 26.0™. We used absolute and relative frequencies for categorical variables and mean and standard deviation for continuous variables. Results: The sample consisted of 193 children, at mean age of 50.3±7.6 months. We observed a predominance of children with cerebral palsy (CP) with Gross Motor Function Classification System (GMFCS) level V (93.7%). Epilepsy (88.4%) was the most common comorbidity. CPCHILDTM mean scores were activities of daily living (ADL)/personal care 43.2±12.6; positioning, transferring and mobility 33.7±16.5; comfort and emotions 84.4±15.2; communication and social interaction (CoSI) 48.2±24.3; health 70.9±17.1; and overall quality of life (OQOL) 72.1±17.1. Total score was 54.8±11.3. Conclusions: Among children with cerebral palsy (CP) related to congenital Zika syndrome, the quality of life (QOL) scores were very similar to other populations with cerebral palsy (CP). The activities of positioning, transferring and mobility had the greatest impact on health-related quality of life (QOL). Rehabilitation strategies and public policies should prioritize aspects related to mobility for this population.

RESUMO Objetivo: Descrever a qualidade de vida relacionada à saúde em crianças com paralisia cerebral associada à infecção congênita pelo zika. Métodos: Estudo transversal de série consecutiva de casos de crianças acompanhadas em uma rede multicêntrica de reabilitação no Brasil. Convidamos o(s) cuidador(es) a responder à versão brasileira do Caregiver Priorities & Child Health Index of Life with Disabilities (CPCHILDTM). A análise estatística foi realizada com o pacote estatístico Statistical Package for the Social Sciences (SPSS) 26.0™. Para variáveis categóricas, foram utilizadas frequências absolutas e relativas e, para variáveis contínuas, média e desvio padrão. Resultados: Cento e noventa e três crianças, com idade média de 50,3±7,6 meses, foram incluídas. Observou-se predomínio de crianças com paralisia cerebral Gross Motor Function Classification System (GMFCS) nível V (93,7%). Epilepsia (88,4%) foi a comorbidade mais comum. As pontuações médias do CPCHILDTM foram: atividades de vida diária/cuidados pessoais 43,2±12,6; posicionamento, transferência e mobilidade 33,7±16,5; conforto e emoções 84,4±15,2; comunicação e interação social 48,2±24,3; saúde 70,9±17,1; e qualidade de vida geral 72,1±17,1. A pontuação total foi 54,8±11,3. Conclusões: Entre as crianças com paralisia cerebral relacionada à síndrome do zika congênita, as atividades de posicionamento, transferência e mobilidade tiveram maior impacto na qualidade de vida relacionada à saúde, semelhantemente a outras etiologias de paralisia cerebral. As estratégias de reabilitação e as políticas públicas devem priorizar os aspectos relacionados à mobilidade dessa população.

https://doi.org/10.1590/1984-0462/2023/41/2022016

Assessment of the cytogenetics and leaf anatomy of synthetic polyploids of Eucalyptus clones
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Souza, Thaise da Silva

; Macedo, Jamile Paiva

; Ferreira, Marco Túlio Mendes

; Moraes, Isabella de Campos

; Castro, Evaristo Mauro de

; Ramalho, Magno Antonio Patto

; Mingossi, Fabiana Bombonato

; Missiaggia, Alexandre Alves

; Techio, Vania Helena

Crop Breeding and Applied Biotechnology

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2023, Volume 23 N. 1 elocation e43762316

Abstract: En | Text: En | PDF: En

Abstract The induction of polyploidy in Eucalyptus can lead to higher-yielding and more adapted clones, with better wood quality. After artificial polyploidization, it is necessary to certify the effectiveness of the process through cytogenetic analyses and anatomical trait evaluations. Thus, the aim of this study was to certify the chromosome duplication in artificially polyploidized clones of Eucalyptus grandis × Eucalyptus urophylla using cytogenetic analysis, flow cytometry, and leaf anatomy measurements. Chromosomal counts and DNA content estimation allowed the identification of artificially polyploidized clones and mixoploids. Polyploid clones had larger stomata diameter than diploids. The increase in stomata size was accompanied by lower stomatal density in most polyploid clones. The typical gigas effect of polyploidized plants was demonstrated by the expressive increase in leaf area in polyploid individuals compared to diploids. Our findings indicate that the use of polyploidy in Eucalyptus breeding is promising, allowing the discrimination of diploid, tetraploid, and mixoploid plants.

https://doi.org/10.1590/1984-70332023v23n1a6

Tradução e adaptação cultural da COVID-19 Anxiety Scale no Brasil
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Ferreira, Layana Giselly Silva

; Pellegrini, Andrea Regina

; Santos, Diana Gabriela Mendes dos

; Carvalho, Dayara de Nazaré Rosa de

; Orlandi, Fabiana de Souza

Estudos de Psicologia (Campinas)

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2023, Volume 40 elocation e220017

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective This study aimed to translate and culturally adapt the COVID-19 Anxiety Scale for the Brazilian context. Method Cross-sectional and methodological study that encompassed the following stages: initial translation, synthesis of translations, back-translation, expert committee review, and pre-testing. Results The COVID-19 Anxiety Scale was initially translated into Portuguese by two translators. A consensus version was established and then back-translated into English by a different translator. Eight experts reviewed these versions, resulting in modifications to two of the seven scale items. This led to the creation of the pre-final version of the COVID-19 Anxiety Scale. Finally, the pre-testing of this version was conducted with 47 individuals, who found the scale to be clear and understandable. Conclusion In conclusion, the COVID-19 Anxiety Scale was adequately translated and culturally adapted for the Brazilian context, and further research is intended to verify evidence of the scale’s validity.

Resumo Objetivo Este estudo objetivou traduzir e adaptar culturalmente a COVID-19 Anxiety Scale para o contexto brasileiro. Método Trata-se de um estudo transversal e metodológico, que seguiu as seguintes etapas: tradução inicial, síntese das traduções, retrotradução, revisão por um comitê de especialistas e pré-teste. Resultados Inicialmente dois tradutores fizeram uma primeira tradução da COVID-19 Anxiety Scale para o português. Depois, estabeleceu-se a versão consensual, que foi retrotraduzida para o idioma inglês por outro tradutor. Posteriormente, as versões da COVID-19 Anxiety Scale foram revistas por oito especialistas. Após a análise, dois dos sete itens da escala foram modificados, obtendo--se a versão pré-final da COVID-19 Anxiety Scale. Por fim, essa última versão do instrumento foi pré-testada com 47 pessoas, que consideraram a escala clara e compreensível. Conclusão Conclui-se, portanto, que a COVID-19 Anxiety Scale foi adequadamente traduzida e adaptada para o contexto brasileiro e almeja-se dar seguimento à pesquisa para verificar evidências de validade da escala.

https://doi.org/10.1590/1982-0275202340e220017

Association between frailty and depression among hemodialysis patients: a cross-sectional study
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Santos, Diana Gabriela Mendes dos

; Ferreira, Layana Giselly Silva

; Pallone, Joice Marques

; Ottaviani, Ana Carolina

; Santos-Orlandi, Ariene Angelini

; Pavarini, Sofia Cristina Iost

; Zazzetta, Marisa Silvana

; Orlandi, Fabiana de Souza

Sao Paulo Medical Journal

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jun 2022, Volume 140 N. 3 Pages 406 - 411

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Frailty is consensually understood to be a clinical syndrome in which minimal stressors can lead to negative outcomes such as hospitalization, early institutionalization, falls, functional loss and death. Frailty is more prevalent among patients with chronic kidney disease (CKD), and those on dialysis are the frailest. Depression contributes towards putting patients with CKD into the frailty cycle. OBJECTIVE: To assess frailty and its relationship with depression among patients with CKD undergoing hemodialysis. DESIGN AND SETTING: Observational and quantitative cross-sectional study conducted in a renal therapy unit, located in the interior of the state of São Paulo, Brazil. METHODS: This investigation took place in 2019, among 80 patients. The following instruments were applied: a sociodemographic, economic and health condition characterization and the Subjective Frailty Assessment (SFA) and Patient Health Questionnaire-9 (PHQ-9). RESULTS: Among the patients, there was higher prevalence of females, individuals with a steady partner and retirees, and their mean age was 59.63 (± 15.14) years. There was high prevalence of physical frailty (73.8%) and depression (93.7%). Depression was associated with frailty, such that patients with depression were 9.8 times more likely to be frail than were patients without depression (odds ratio, OR = 9.80; 95% confidence interval, CI, 1.93-49.79). CONCLUSION: Based on the proposed objective and the results achieved, it can be concluded that depression was associated with the presence of frailty among patients with CKD on hemodialysis.

https://doi.org/10.1590/1516-3180.2021.0556.r1.14092021

Relationship between frailty, social support and family functionality of hemodialysis patients: a cross-sectional study
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Santos, Diana Gabriela Mendes dos

; Pallone, Joice Marques

; Manzini, Carlene Souza Silva

; Zazzetta, Marisa Silvana

; Orlandi, Fabiana de Souza

Sao Paulo Medical Journal

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dec 2021, Volume 139 N. 6 Pages 570 - 575

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: The population with chronic kidney disease (CKD) is more predisposed to early development of frailty. Although the concept of frailty is well established from a physical point of view, it is not an exclusively physical syndrome. It can be characterized as an interaction of physical, psychological and social factors. OBJECTIVE: To ascertain the relationship between frailty, social support and family functionality among CKD patients undergoing hemodialysis. DESIGN AND SETTING: Correlational, cross-sectional and quantitative study conducted at a service in the interior of the state of São Paulo. METHODS: This study included 80 patients with CKD who were on hemodialysis. The participants were interviewed individually, with application of the following instruments: sociodemographic and economic characterization, Tilburg Frailty Indicator, Medical Outcomes Study and Family APGAR. Females and white ethnicity predominated among the participants, and their mean age was 59.63 ± 15.14 years. RESULTS: There was high prevalence of frailty (93.8%). Although there was a difference in scores for the dimensions of social support between the frail group and the non-frail group, only family functionality reached a statistically relevant difference. There was a significant correlation between physical frailty, social support and family functionality. CONCLUSIONS: Presence of frailty is related to the social support and family functionality of patients with CKD undergoing hemodialysis.

https://doi.org/10.1590/1516-3180.2021.0089.r1.0904221

COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience
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Gomes, Walter J.

; Rocco, Isadora

; Pimentel, Wallace S.

; Pinheiro, Aislan H. B.

; Souza, Paulo M. S.

; Costa, Luiz A. A.

; Teixeira, Marjory M. P.

; Ohashi, Leonardo P.

; Bublitz, Caroline

; Begot, Isis

; Moreira, Rita Simone L

; Hossne Jr, Nelson A.

; Vargas, Guilherme F.

; Branco, João Nelson R.

; Teles, Carlos A.

; Medeiros, Eduardo A. S.

; Sáfadi, Camila

; Rampinelli, Amândio

; Moratelli Neto, Leopoldo

; Rosado, Anderson Rosa

; Mesacasa, Franciele Kuhn

; Capriata, Ismael Escobar

; Segalote, Rodrigo Coelho

; Palmieri, Deborah Louize da Rocha Vianna

; Jardim, Amanda Cristina Mendes

; Vianna, Diego Sarty

; Coutinho, Joaquim Henrique de Souza Aguiar

; Jazbik, João Carlos

; Coutinho, Henrique Madureira da Rocha

; Kikuta, Gustavo

; Almeida, Zely Sant'Anna Marotti de

; Feguri, Gibran Roder

; Lima, Paulo Ruiz Lucio de

; Franco, Anna Carolina

; Borges, Danilo de Cerqueira

; Cruz, Felipe Ramos Honorato De La

; Croti, Ulisses Alexandre

; Borim, Bruna Cury

; Marchi, Carlos Henrique De

; Goraieb, Lilian

; Postigo, Karolyne Barroca Sanches

; Jucá, Fabiano Gonçalves

; Oliveira, Fátima Rosane de Almeida

; Souza, Rafael Bezerra de

; Zilli, Alexandre Cabral

; Mas, Raul Gaston Sanchez

; Bettiati Junior, Luiz Carlos

; Tranchesi, Ricardo

; Bertini Jr, Ayrton

; Franco, Leandro Vieira

; Fernandes, Priscila

; Oliveira, Fabiana

; Moraes Jr, Roberto

; Araújo, Thiago Cavalcanti Vila Nova de

; Braga, Otávio Penna

; Pedrosa Sobrinho, Antônio Cavalcanti

; Teixeira, Roberta Tavares Barreto

; Camboim, Irla Lavor Lucena

; Gomes, Eduardo Nascimento

; Reis, Pedro Horigushi

; Garcia, Luara Piovan

; Scorsioni, Nelson Henrique Goes

; Lago, Roberto

; Guizilini, Solange

Brazilian Journal of Cardiovascular Surgery

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dec 2021, Volume 36 N. 6 Pages 725 - 735

Abstract: En | Text: En | PDF: En

Abstract Introduction: We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative period. Methods: A retrospective multicenter study including 104 patients who were allocated in three groups according to time of positive real time reverse transcriptase-polymerase chain reaction (RT-PCR) for the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2): group 1, patients who underwent cardiac surgery > 10 days after positive RT-PCR; group 2, patients with a positive RT-PCR within 10 days before or after surgery; group 3, patients who presented positive RT-PCR > 10 days after surgery. The primary outcome was mortality and secondary outcomes were postoperative complications, intensive care unit (ICU) length of stay, and postoperative days of hospitalization. Results: The three groups were similar with respect to age, the European System of Cardiac Operative Risk Evaluation score, and comorbidities, except hypertension. Postoperative complications and death were significantly higher in groups 2 and 3 than in group 1, and no significant difference between groups 2 and 3 was seen. Group 2 showed a high prevalence of surgery performed as an urgent procedure. Although no significant differences were observed in ICU length of stay, total postoperative hospitalization time was significantly higher in group 3 than in groups 1 and 2. Conclusion: COVID-19 affecting the postoperative period of patients who underwent cardiovascular surgery is associated with a higher rate of morbidity and mortality. Delaying procedures in RT-PCR-positive patients may help reduce risks of perioperative complications and death.

https://doi.org/10.21470/1678-9741-2021-0960

THE EFFECTS OF A BRIEF SUPPORTIVE PSYCHOTHERAPEUTIC INTERVENTION AMONG HEMODIALYZED PATIENTS: A QUASI-EXPERIMENTAL STUDY
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Manzini, Carlene Souza Silva

; Damasceno, Vanessa Almeida Maia

; Santos, Diana Gabriela Mendes dos

; Miranda Neto, Milton

; Sousa, Clemente Neves de

; Elias, Ana Catarina Araújo

; Orlandi, Fabiana de Souza

Texto & Contexto - Enfermagem

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2021, Volume 30 elocation e20200116

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos avaliar a qualidade de vida relacionada à saúde e a resiliência de pacientes hemodialisados na cidade do Porto, Portugal, antes e após a intervenção psicoterapêutica Relaxamento, Imagens Mentais e Espiritualidade. Identificar os fatores que interferem nos níveis de resiliência destes pacientes. Método estudo quase-experimental, realizado com 17 participantes de duas unidades de diálise da cidade do Porto, Portugal, de novembro de 2018 a abril de 2019. Foram utilizados questionário de caracterização sociodemográfica e clínica, escala de qualidade de vida (Kidney Disease Quality of Life-Short Form), escala de resiliência, e intervenção psicoterapêutica breve. Cada paciente recebeu três sessões da intervenção, sendo avaliados pelos instrumentos listados antes e depois. Foram utilizados testes de Shapiro Wilks para verificar normalidade dos dados, testes t de Student e de Wilcoxon para comparação das médias e regressão linear na identificação dos fatores associados à resiliência. Resultados a percepção da qualidade de vida foi melhor em quase todos os domínios da escala pós-intervenção, com diferença estatisticamente significativa nas dimensões: função física (p=0,006) e função emocional (p=0,021). Na avaliação da resiliência, verificou-se aumento com significância estatística no período pós-intervenção (p=0,002); análises de regressão linear revelaram que religião, outras patologias e histórico de transplante são fatores relacionados ao aumento dos níveis de resiliência; e uso de medicamentos antidepressivos e anti-hipertensivos são fatores que podem interferir na diminuição da resiliência. Conclusão a intervenção contribuiu para melhora na resiliência e de alguns domínios da qualidade de vida dos pacientes, podendo ser estimulada sua aplicabilidade no contexto dos pacientes em hemodiálise.

ABSTRACT Objectives to assess health-related quality of life and resilience among hemodialyzed patients in the city of Porto, Portugal, before and after the Relaxation, Mental Images and Spirituality psychotherapeutic intervention, and identify factors interfering in these patients’ levels of resilience. Method a quasi-experimental study was conducted from November 2018 to April 2019 among 17 patients attending two dialysis centers located in Porto, Portugal. A questionnaire addressing sociodemographic and clinical information was applied together with the Kidney Disease Quality of Life-Short Form, a resilience scale, and a brief psychotherapeutic intervention. Each patient attended three intervention sessions, and the instruments were applied before and after the intervention. The Shapiro-Wilk test was performed to verify the normality of data, while the Student’s t-test and Wilcoxon test were performed to compare the means, and linear regression was used to identify resilience-associated factors. Results after the intervention, quality of life perception improved in virtually all the scale’s domains, with statistically significant differences in the physical function (p=0.006) and emotional function (p=0.021). The resilience assessment revealed a statistically significant improvement in the post-intervention (p=0.002); linear regression analyses showed that having a religion, other pathologies, or a history of transplant is related to increased resilience levels while taking antidepressants or anti-hypertensive medications negatively affect it. Conclusion the intervention contributed to improving resilience and some domains concerning the patients’ quality of life. Thus, it can be implemented among patients undergoing hemodialysis.

RESUMEN Objetivos evaluar la calidad de vida relacionada a la salud y resiliencia de pacientes en hemodiálisis, en la ciudad do Porto, en Portugal, antes y después de la intervención psicoterapéutica: Relajamiento, Imágenes Mentales y Espiritualidad. También, identificar los factores que interfieren en los niveles de resiliencia de estos pacientes. Método estudio casi experimental, realizado en 17 participantes de dos unidades de diálisis de la ciudad de Porto, en Portugal, de noviembre de 2018 a abril de 2019. Fueron utilizados: el cuestionario de caracterización sociodemográfica y clínica, la escala de calidad de vida (Kidney Disease Quality of Life-Short Form), la escala de resiliencia y la intervención psicoterapéutica breve. Cada paciente recibió tres sesiones de intervención, siendo evaluados por los instrumentos arriba listados, antes y después. Fueron utilizadas las pruebas: Shapiro Wilks para verificar la normalidad de los datos, t de Student y de Wilcoxon para comparación de las medias; y, la regresión linear para la identificación de los factores asociados a la resiliencia. Resultados la percepción de la calidad de vida fue mejor en casi todos los dominios de la escala, después de la intervención, con una diferencia estadísticamente significativa en las dimensiones: función física (p=0,006) y función emocional (p=0,021). En la evaluación de la resiliencia, se verificó aumento con significación estadística, en el período después de la intervención (p=0,002). Los análisis de regresión linear revelaron que la religión, otras patologías y el histórico de trasplante, son factores relacionados con el aumento de los niveles de resiliencia; y, el uso de medicamentos antidepresivos y antihipertensivos son factores que pueden interferir en la disminución de la resiliencia. Conclusión la intervención contribuyó para la mejora de la resiliencia y de algunos dominios de la calidad de vida de los pacientes, pudiendo ser estimulada su aplicabilidad en el contexto de los pacientes en hemodiálisis.

https://doi.org/10.1590/1980-265x-tce-2020-0116

[SciELO Preprints] - Partnership between the academy and public and private health systems to fight the COVID-19: an experience report in Tubarão, Santa Catarina, Brazil
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Schuelter-Trevisol, Fabiana Iser, Betine Pinto Moehlecke Marcon, Chaiana Esmeraldino Mendes Mello, Rogério Sobroza de Souza, Kellen Meneghel de Baldessar, Maria Zélia Trevisol, Daisson José

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Publication date: 2020-08-13

Abstract: En Pt

This article presents a report on the integration experience of health stakeholders, including public and private health systems, a university and authorities for the surveillance and control of the COVID-19 epidemic, in the municipality of Tubarão, Santa Catarina, Brazil. The city has a large flow of people from different parts of the country, and was one of the first municipalities in the state of Santa Catarina to report cases of community transmission by SARS-CoV-2. The measures adopted included the implementation of the COVID-19 Monitoring Committee, the Health Center for Municipal Emergency Operations, and the Disease Contingency Plan. After 100 days of pandemic, 5,979 cases were reported, 431 (7.2%) confirmed, of which five (1.2%) died. Early decisions, such as the immediate suspension of business activities and crowding events, have reduced the spread of the virus. The established partnership provided innovation and subsidized public management in decision-making based upon scientific evidence.

Apresenta-se o relato de experiência da integração entre serviços de saúde públicos e privados, gestores e universidade, para a vigilância e controle da epidemia de covid-19 em Tubarão, SC, Brasil. A cidade, universitária, cenário de grande fluxo de pessoas de diferentes locais do país, foi um dos primeiros municípios do estado catarinense com transmissão comunitária do SARS-CoV-2. São detalhadas as medidas adotadas com a criação do Comitê de Monitoramento da Covid-19, do Centro de Operações de Emergências Municipais em Saúde, e do Plano de Contingência da Doença. Passados 100 dias de pandemia, foram 5.979 casos notificados e 431 (7,2%) confirmados, dos quais 5 (1,2%) idos a óbito. Decisões precoces – suspensão imediata das atividades de comércio e eventos com aglomeração – podem ter limitado a propagação do vírus. As parcerias estabelecidas trazem inovação e subsidiam a gestão pública nas tomadas de decisão pautadas em evidências científicas.

https://doi.org/10.1590/SciELOPreprints.1060

10.

Parceria de serviços de saúde públicos e privados com a academia, no combate à COVID-19: relato de experiência em Tubarão, Santa Catarina
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Schuelter-Trevisol, Fabiana

; Iser, Betine Pinto Moehlecke

; Marcon, Chaiana Esmeraldino Mendes

; Mello, Rogério Sobroza de

; Souza, Kellen Meneghel de

; Baldessar, Maria Zélia

; Trevisol, Daisson José

Epidemiologia e Serviços de Saúde

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2020, Volume 29 N. 4 elocation e2020499

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Apresenta-se o relato de experiência da integração entre serviços de saúde públicos e privados, gestores e universidade, para a vigilância e controle da epidemia de COVID-19 em Tubarão, SC, Brasil. A cidade, universitária, cenário de grande fluxo de pessoas de diferentes locais do país, foi um dos primeiros municípios do estado catarinense com transmissão comunitária do SARS-CoV-2. São detalhadas as medidas adotadas com a criação do Comitê de Monitoramento da COVID-19, do Centro de Operações de Emergências Municipais em Saúde, e do Plano de Contingência da Doença. Passados 100 dias de pandemia, foram 5.979 casos notificados e 431 (7,2%) confirmados, dos quais 5 (1,2%) foram a óbito. Decisões precoces – suspensão imediata das atividades de comércio e eventos com aglomeração – podem ter limitado a propagação do vírus. As parcerias estabelecidas trazem inovação e subsidiam a gestão pública nas tomadas de decisão pautadas em evidências científicas.

Abstract This article presents an experience report about integration between public and private health services, health service managers and the academy, for surveillance and control of the COVID-19 epidemic, in the municipality of Tubarão, Santa Catarina, Brazil. The city is home to a university and has a large flow of people from different parts of the country, as well as being one of the first municipalities in the state of Santa Catarina to report cases of community transmission of SARS-CoV-2. The measures adopted included the implementation of the COVID-19 Monitoring Committee, the Municipal Health Emergency Operations Center, and the COVID-19 Contingency Plan. After 100 days of pandemic, 5,979 cases had been reported, 431 (7.2%) had been confirmed, of which five (1.2%) died. Early decisions, such as the immediate suspension of business activities and crowded events, may have reduced the spread of the virus. The partnerships put into place have provided innovation and supported public service management in decision-making based upon scientific evidence.

Resumen Se presenta la experiencia de la integración entre los servicios de Salud Pública y privados, los administradores y la universidad para la vigilancia y el control de la epidemia de COVID-19 en Tubarão, Santa Catarina, Brasil. La ciudad universitaria, con un gran flujo de personas de diferentes partes del país, fue uno de los primeros municipios del estado con transmisión comunitaria de SARS-CoV-2. Las medidas adoptadas se detallan con la creación del Comité de Monitoreo COVID-19, el Centro de Operaciones Municipales de Emergencia en Salud y un Plan de Contingencia de la Enfermedad. Después de 100 días de pandemia, se reportaron 5,979 casos, 431 (7,2%) confirmados, de los cuales cinco (1,2%) murieron. Las decisiones precoces, la suspensión inmediata de las actividades comerciales y de los eventos con aglomeración han reducido la propagación del virus. Las asociaciones establecidas aportan innovación y subsidian la gestión pública en la toma de decisiones basadas en evidencia científica.

https://doi.org/10.1590/s1679-49742020000400024

11.

Parceria de serviços de saúde públicos e privados com a academia, no combate à COVID-19: relato de experiência em Tubarão, Santa Catarina
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Schuelter-Trevisol, Fabiana

; Iser, Betine Pinto Moehlecke

; Marcon, Chaiana Esmeraldino Mendes

; Mello, Rogério Sobroza de

; Souza, Kellen Meneghel de

; Baldessar, Maria Zélia

; Trevisol, Daisson José

Epidemiologia e Serviços de Saúde

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2020, Volume 29 N. 4 elocation e2020499

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/s1679-49742020000400024 1683 downloads

12.

Pp65 antigenemia and cytomegalovirus diagnosis in patients with lupus nephritis: report of a series.
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Lino, Katia

; Trizzotti, Natalia

; Carvalho, Fabiana Rabe

; Cosendey, Rachel Ingrid

; Souza, Cintia Fernandes

; Klumb, Evandro Mendes

; Silva, Andrea Alice

; Almeida, Jorge Reis

Brazilian Journal of Nephrology

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mar 2018, Volume 40 N. 1 Pages 44 - 52

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Diferentemente do transplante de órgãos, poucos estudos correlacionam o monitoramento da antigenemia pp65 com o diagnóstico de citomegalovírus (CMV) em pacientes com lúpus eritematoso sistêmico (LES). Objetivo: De modo a destacar a importância do CMV para além do transplante, monitorizamos a antigenemia pp65 em uma série de pacientes com LES. Métodos: De março de 2015 a março de 2016, pacientes com LES que apresentaram acometimento renal, febre e infecção indeterminada na internação foram monitorados através da antigenemia pp65. O ensaio de antigenemia, revelada por imunofluorescência, foi correlacionado com achado clínicos e laboratoriais. Resultados: Foram incluídos 19 pacientes com suspeita de infecção indeterminada. Positividade para antigenemia pp65 foi encontrada em sete pacientes (36,8%). A idade média foi de 33,5 ± 11,2 anos; 16 (84%) eram do sexo feminino e 16 (84%) eram negros. Linfopenia, anemia e escore de SLEDAI mais elevado foram significativamente mais comuns em pacientes pp65 positivos. Cinco pacientes receberam terapia antiviral com ganciclovir. Apesar de receber tratamento específico para CMV, um paciente com suspeita de doença por CMV veio a óbito. Conclusões: Antigenemia pp65 pode ser relevante em pacientes com LES, e estudos com maior número de pacientes são necessários para estabelecer a sensibilidade e a especificidade da antigenemia pp65 em diferentes contextos clínicos envolvendo pacientes com LES.

ABSTRACT Introduction: In contrast to organ transplantation, few studies correlate the monitoring of pp65 antigenemia with a diagnosis of cytomegalovirus (CMV) in patients with systemic lupus erythematosus (SLE). Objective: To highlight the importance of CMV outside transplantation, we monitored pp65 antigenemia in a series of SLE patients. Methods: From March 2015 to March 2016, SLE patients presenting kidney involvement, fever, and an unclear infection at hospital admission were monitored through pp65 antigenemia. The pp65 antigenemia assay, revealed by immunofluorescence, was correlated with clinical and laboratory findings. Results: We included 19 patients with a suspected unclear infection. A positivity for pp65 antigenemia was found in seven patients (36.8%). The mean age was 33.5 ± 11.2 years, 16 (84%) were females, and 16 (84%) were black. Lymphopenia, anemia, and higher scores of SLEDAI were significantly more common in pp65-positive patients. Five patients received antiviral therapy with ganciclovir. Although receiving specific CMV treatment, one patient died because of suspected CMV disease. Conclusions: Pp65 antigenemia might be relevant in SLE patients, and studies with a greater number of patients are needed in order to establish sensitivity and specificity of pp65 antigenemia in different clinical contexts of SLE patients.

https://doi.org/10.1590/2175-8239-jbn-3838 3994 downloads

13.

Vulnerabilidades ao HIV/aids no Contexto Brasileiro: iniquidades de gênero, raça e geração
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Garcia, Sandra

; Souza, Fabiana Mendes de

Saúde e Sociedade

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dec 2010, Volume 19 Suppl. 2 Pages 9 - 20

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: Analisar o conhecimento da população sobre DST/aids, bem como os discursos sobre o uso do preservativo e das práticas sexuais. MÉTODOS: Pesquisa qualitativa com 64 indivíduos jovens e adultos, brancos e negros, sexualmente ativos, de ambos os sexos. A vulnerabilidade ao HIV/aids foi discutida a partir da perspectiva racial (negros ou brancos), geracional (entre 16 e 24 anos ou 45 e mais) e de gênero (masculino ou feminino). Foram realizadas entrevistas em profundidade com roteiro semiestruturado nas cidades de São Paulo (SP) e Recife (PE), sobre os temas: conhecimento e percepção sobre DST/aids, percepção de risco individual, negociação e uso de preservativos, iniciação sexual e práticas sexuais. RESULTADOS: Os indivíduos menos escolarizados, os homens, os mais velhos e os moradores de Recife foram os menos informados sobre DST/aids. Pessoas acima de 45 anos e os menos escolarizados possuíam conhecimento incipiente sobre as formas de transmissão e prevenção das DST/aids. O uso do preservativo entre os entrevistados de ambas as cidades foi relativamente baixo; a não utilização do preservativo entre as mulheres em relação estável foi atribuída à negativa do parceiro. Entre os entrevistados que declararam usar o preservativo, o tipo de relação estabelecida e a fase do relacionamento resultaram em padrões de uso diversificados; o uso consistente do preservativo foi mais frequente nas parcerias eventuais. CONCLUSÕES: O conhecimento incipiente aliado à prática sexual insegura coloca mulheres unidas, de baixa escolaridade, menor renda, sobretudo acima dos 45 anos, e os residentes de Recife em situação de maior vulnerabilidade às DST/aids.

OBJECTIVE: The objective of this paper is to assess the level of knowledge and information held by the population about HIV/AIDS, and to analyze discourses about condom use and sexual practices. METHODS: Qualitative research with 64 young people and adults, black and white, sexually active men and women. Vulnerability to HIV/AIDS was discussed from the perspective of racial (black or white), generational (between 16 and 45 or 24 years or older) and gender (male or female). In-depth interviews were conducted with a semi-structured script in the cities of São Paulo (SP) and Recife (PE) on the following themes: knowledge and perception about STD/AIDS, perception of individual risk, negotiation and condom use, sexual initiation and practices. RESULTS: The least-educated, men, elders and residents of Recife were the least informed persons as regards to HIV/AIDS. People over 45 years and the less educated had incipient knowledge about transmission and prevention of STD/AIDS. Condom use among respondents in both cities was relatively low, non-use of condoms among women in stable relationship was attributed to partner's refusal to using it. Among respondents who reported using condoms, the type of relationship established and the phase of the relationship resulted in varied patterns of use; the consistent use of condoms was more common in occasional partnerships. CONCLUSIONS: The incipient knowledge in association with unsafe sexual practice puts women in stable relationship, poorly educated, lower income, particularly above 45 years, and residents of Recife in a situation of greater vulnerability to STD/AIDS.

528 downloads Cited 27 times in SciELO

14.

Vulnerabilidades ao HIV/aids no Contexto Brasileiro: iniquidades de gênero, raça e geração
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Garcia, Sandra

; Souza, Fabiana Mendes de

Saúde e Sociedade

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dec 2010, Volume 19 Suppl. 2 Pages 9 - 20

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

18839 downloads Cited 27 times in SciELO

15.

Desenvolvimento ponderal e diversidade fenotípica entre cruzamentos de ovinos Dorper com raças locais
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Carneiro, Paulo Luiz Souza

; Malhado, Carlos Henrique Mendes

; Souza Júnior, Antonio Alcione Oliveira de

; Silva, Antonio Gonçalves Serafim da

; Santos, Fabiana Nery dos

; Santos, Pollianna Ferro

; Paiva, Samuel Rezende

Pesquisa Agropecuária Brasileira

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jul 2007, Volume 42 N. 7 Pages 991 - 998

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O objetivo deste trabalho foi comparar o desenvolvimento ponderal, por meio de curva de crescimento e pesos ajustados e avaliar a diversidade entre ovinos cruzados Dorper com as raças locais, com base em características de carcaça e morfológicas. Foram realizadas pesagens dos animais cruzados em intervalos de aproximadamente 15 dias e avaliados os efeitos de sexo, ano e grupo genético. Na estimativa dos parâmetros das curvas, foi utilizado o modelo não-linear Logístico e, a fim de avaliar o grau de similaridade entre os animais dos grupos genéticos, foram utilizadas variáveis canônicas. O sexo dos animais não influenciou o peso. Houve efeito de ano e grupo genético sobre o desenvolvimento dos animais. Conforme o modelo Logístico para a curva de crescimento, o grupo genético Dorper x Santa Inês apresentou maior velocidade de crescimento, estimado pelo peso à maturidade e taxa de maturação, seguido dos grupos genéticos Dorper x Morada Nova e Dorper x Rabo Largo. A análise de agrupamento ressaltou as diferenças entre os grupos genéticos e alocou os três cruzamentos em dois grupos, um formado pelos cruzamentos Dorper x Morada Nova e Dorper x Rabo Largo e o outro pelo cruzamento Dorper x Santa Inês.

The goal of this work was to compare growth rate, by mean of growth and adjusted weight curves, and to analyze the diversity among crosses of Dorper ovines and local breeds, based on morphological and carcass features. Crossed animals were weighed in a 15-day-interval and the effects of sex, year and genetic group were analyzed. The non-linear Logistic model was used to estimate curve parameters and the degree of similarity among genetic groups was evaluated through canonic variables. Sex did not influence significantly on weight. There was a significant effect related to year and genetic group over animal's development. The estimates of growth curve based on parameters from the Logistic model indicated that the genetic group Dorper x Santa Inês presented a faster growth rate, as estimated by weight at maturity and maturity rate, followed by the genetic groups Dorper x Morada Nova and Dorper x Rabo Largo. Clustering analysis reinforced the differences among genetic groups, placing the three crosses in two groups, one comprising Dorper x Morada Nova and Dorper x Rabo Largo, and another including the cross Dorper x Santa Inês.

5133 downloads Cited 1 time in SciELO

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