ABSTRACT Diets with high energy density and additives that enhance energy use are necessary for finishing feedlot cattle. The objective of the present study was to evaluate the performance, ingestive behavior, apparent digestibility of the diet and the carcass traits of feedlot steers fed concentrates from different energy sources, one derived from starchy sources and the other, from lipid sources, combined or not with whole soy lecithin, at a dose of 40 g animal day-1. The experimental design was completely randomized blocks, in a 2 x 2 factorial arrangement. The combination of whole soy lecithin with the lipid energy source concentrate increased the dry matter digestibility and the carcass yield of the animals (76.03% and 57.20%, respectively). The lipid energy source concentrate showed higher ether extract digestibility and animals fed on it had higher carcass yield (84.18% and 56.85%, respectively). Whole soy lecithin promoted a reduction in fecal pH due to a greater fermentation of carbohydrates and fatty acids in the intestinal lumen. Using whole soy lecithin combined with energy concentrate from a lipid source is recommended due to its improvements in the use of the diet and in the carcass yield.

RESUMO O uso de dietas com alta densidade energética e aditivos que potencializem o aproveitamento energético se faz necessário na terminação de bovinos em confinamento. O objetivo do presente estudo foi avaliar o desempenho, o comportamento ingestivo, a digestibilidade aparente da dieta e as características de carcaça de novilhos confinados, alimentados com concentrados de diferentes fontes energéticas, um derivado de fontes amiláceas e outro de fontes lipídicas, associados ou não com lecitina integral de soja, na dose de 40g animal dia-1. O delineamento experimental foi o de blocos inteiramente ao acaso, em esquema fatorial 2 x 2. A associação da lecitina integral de soja com o concentrado de fonte energética lipídica melhorou a digestibilidade da matéria seca e o rendimento de carcaça dos animais (76,03% e 57,20%, respectivamente). O concentrado de fonte energética lipídica teve maior digestibilidade do extrato etéreo, e os animais alimentados com este possuíram maior rendimento de carcaça (84,18% e 56,85%, respectivamente). A lecitina integral de soja isolada promoveu redução no pH fecal em virtude de uma maior fermentação de carboidratos e ácidos graxos no lúmen intestinal. Utilizar lecitina integral de soja associada com concentrado energético de fonte lipídica é recomendado devido a suas melhorias no aproveitamento da dieta e no rendimento de carcaça.

Abstract Forest fragments are susceptible to environmental shifts and this demands high phenotypic plasticity of the species growing in these areas. In this context, the objective of the present work was to study the phenotypic plasticity of copaíba (Copaifera langsdorffii Desf.) based on morphological and anatomical metrics of the leaflets of plants from six forest fragments. The leaflets of C. langsdorffii individuals of the different fragments did not show qualitative differences, nonetheless, they demonstrated quantitative plasticity. Stomatal density (p = 0.017), specific leaf area (p = 0.009), palisade parenchyma (p = 0.008) and relative water content (p = 0.002), indicated a high luminous, water and nutritional influence on the development of leaflets. Based on the dry mass of the leaflets and the thickness of the palisade parenchyma, the principal component analysis explained 57.43% of the differences found between the variables. The data presented here provides evidence of the phenotypic plasticity of C. langsdorffii which, although occurring in similar soils, showed significant quantitative differences in its morphoanatomical characters.

The cardioprotective effect of postmenopausal hormone replacement therapy (HRT) has been demonstrated in several studies. Similarly, physical exercise has yielded positive results. However, the effects of their combination remain inconclusive. This review describes the combined effects of physical exercise and hormone therapy on cardiovascular and metabolic health in postmenopausal women. We searched the Scopus, Web of Science, PubMed, and Embase databases and included randomized controlled trials published up to December 2021 on the combined effects of physical exercise and hormone therapy on cardiovascular and metabolic health in postmenopausal women. We identified 148 articles, of which only seven met the inclusion criteria (386 participants; 91 [23%] HRT + exercise; 104 [27%] HRT; 103 [27%] exercise; 88 [23%] placebo). The combined treatment further decreased systolic blood pressure (SBP) compared to the isolated effect of aerobic training (AT) (mean difference [MD]=-1.69; 95% confidence interval [CI]=-2.65 to -0.72, n=73). Nevertheless, it attenuated the decrease in diastolic blood pressure (DBP) (MD=0.78; 95%CI: 0.22-1.35, n=73), and the increase in peak oxygen consumption (VO2 peak) promoted by exercise (AT + HRT=2.8±1.4 vs AT + placebo=5.8±3.4, P=0.02). The combination of AT and oral HRT improved SBP. However, AT alone seemed to have a better effect on physical fitness and DBP in postmenopausal women.

Cognitive Load Theory (CLT) and Cognitive Theory of Multimedia Learning (CTML) have been widely studied in the last 30 years, being fundamental for the development of instructional materials for learning that take into account the limitations in human working memory. Although relevant, we show the inexistence of both theories in the curricula of undergraduate courses in Physics. The contribution of this work is to highlight such a gap, thus contributing to discussions aming the incorporation of CLT and CTML in the curricula of Physics teacher education in federal and state universities in the country.

A Teoria da Carga Cognitiva (TCC) e a Teoria Cognitiva da Aprendizagem Multimídia (TCAM) têm sido largamente estudadas nos últimos 30 anos, sendo fundamentais para a elaboração de materiais instrucionais para a aprendizagem que levem em conta as limitações na memória de trabalho humana. Apesar da relevância da TCC e da TCAM, evidenciamos uma lacuna na abordagem a ambas as teorias nos currículos dos cursos de licenciatura plena em Física de universidades públicas brasileiras (federais e estaduais). Nosso objetivo, levantando essa questão, é contribuir com discussões que possam levar a TCC e a TCAM a serem incorporadas aos currículos de formação de professores de Física nas universidades do país.

Nuclear proliferation marker MIB-1 (Ki-67) immunohistochemistry (IHC) is used to examine tumor cell proliferation. However, the diagnostic or prognostic value of the Ki-67 nuclear staining intensity and location, defined as nuclear gradient (NG), has not been assessed. This study examined the potential association between Ki-67 NG and cell cycle phases and its effect on the prognosis of pulmonary typical carcinoid (PTC) tumors. We propose a method for classifying the NG of Ki-67 during the cell cycle and compare the results between PTC, pulmonary adenocarcinoma (PAD), and breast ductal carcinoma (BDC). A literature review and objective analysis of IHC-stained paraffin sections were used to determine the Ki-67 labeling index and composed a stratification of the NG into NG1, NG2, and NG3/4 categories. A semi-automated image analysis protocol was established to determine the Ki-67 NG in PTC, PAD, and BDC. High intraobserver consistency and moderate interobserver agreement were achieved in the determination of Ki-67 NG in tumor specimens. NG1 and NG2 were lower in PTC than in PAD and BDC. Cox multivariate analysis of PTC after adjusting for age and number of metastatic lymph nodes showed that Ki-67 NG1 and NG2 significantly predicted clinical outcomes. The semi-automated method for quantification of Ki-67 nuclear immunostaining proposed in this study could become a valuable diagnostic and prognostic tool in PTC.

Abstract Pure titanium and various alloys, such as Ti-6Al-4V, are widely used as biomaterials. In this application, surface finish conditions, topography, and surface reactivity determine excellent cellular adhesion and osseointegration characteristics. The study evaluated the influence of four surface finishing treatments (sanding #120, 600, 1200, and polished with 3 µm alumina paste) and three shapes (concave, convex, and flat) on the corrosion resistance of Ti-6Al-4V at 37 °C in simulated body fluid (SBF) through potentiodynamic polarization and electrochemical impedance spectroscopy. The SBF's ionic composition allowed the formation of a stable passive layer with a low presence of pores on the surface. In addition, the combination of polished surface and convex shape showed the best electrochemical passive behavior.

Resumo O objetivo deste trabalho foi avaliar a resposta fotossintética ao deficit de pressão de vapor (DPV) em acessos de umbuzeiro (Spondias tuberosa). O experimento foi conduzido em delineamento experimental inteiramente casualizado, em arranjo fatorial 5×7×2 (cinco acessos de umbuzeiro – BRS-68, EPAMIG-05, BGU-61, BGU-75 e BGU-50 –, sete épocas de avaliação e dois momentos de leitura – às 8h e às 14h), em parcelas subsubdivididas no tempo. A temperatura foliar aumentou com a temperatura do ar. A variação da condutância estomática e da transpiração com o DPV não foi significativa. A fotossíntese líquida, a eficiência de carboxilação e a eficiência instantânea do uso da água decresceram com o aumento do DPV em todos os acessos, exceto no BRS-68, cujas taxas se mantiveram positivas.

Abstract The objective of this work was to evaluate the photosynthetic response to vapor pressure deficit (VPD) in umbu (Spondias tuberosa) tree accessions. The experiment was carried out in a completely randomized design in a 5×7×2 factorial arrangement (five umbu accessions – BRS-68, EPAMIG-05, BGU-61, BGU-75, and BGU-50 –, seven evaluation times, and two reading times – at 8 a.m. and 2 p.m.) in split-split plots in time. Leaf temperature increased with air temperature. The variation of stomatal conductance and transpiration with the VPD was not significant. Net photosynthesis rate, carboxylation efficiency, and instantaneous water-use efficiency decreased with increasing VPD in all accessions, except in BRS-68, whose rates remained positive.

Resumo A tolerância à baixa disponibilidade hídrica é fator decisivo para o crescimento e sobrevivência das orquídeas em seu ambiente natural. O objetivo deste estudo foi caracterizar os atributos fotoquímicos de duas orquídeas epífitas (Cattleya warneri e Miltonia spectabilis) sob déficit hídrico (WD). A fluorescência da clorofila a foi registrada em folhas jovens e totalmente expandidas de 5 plantas/espécie adaptadas ao escuro por 60 minutos, entre 6 e 9 h da manhã, a 0, 30, 60 e 90 dias de WD, usando um fluorômetro Handy-PEA (Hansatech, Reino Unido). Aumentos nas fases O-J e J-I, bandas L e K e diminuição da fase I-P foram observados após 30 dias de DW, principalmente em C. warneri. A diminuição da capacidade de redução da quinona A (QA) e das propriedades cinéticas requeridas para reações redox do pool de plastoquinona, a perda de conectividade energética entre unidades de fotossistema II (FSII), a inativação do complexo de evolução do oxigênio e a manutenção da taxa global de redução do pool aceptores de elétrons do fotossistema I foram observadas em M. spectabilis, espécie evidentemente mais tolerante. A maior habilidade dessa espécie em manter o conteúdo relativo de água nos tecidos fotossintéticos permite maior atividade fotoquímica.

Abstract The tolerance to low water availability is a decisive factor for growth and survival of orchids in their natural environment. The objective of this study was to characterize the photochemical traits of two epiphytic orchids (Cattleya warneri and Miltonia spectabilis) under water deficit (WD). Chlorophyll a fluorescence signals were recorded from young and fully expanded leaves of 5 plants/species after dark-adaption for 60 minutes, between 6-9 a.m. after 0, 30, 60, and 90 days of WD, using a Handy-PEA fluorometer (Hansatech, UK). Increases of O-J and J-I phases and L and K-bands and decreases of I-P phase were observed after 30 days of WD, especially in C. warneri. Decreases in the capacity to photochemically reduce quinone A (QA) and the kinetic properties required for redox reactions of the plastoquinone pool, the loss of energetic connectivity between units of PSII, inactivation of the oxygen evolution complex, and decrease of the overall rate of reducing the electron acceptor pool of photosystem I were observed in M. spectabilis, a more tolerant species. The greater ability of this species to maintain higher relative water content (RWC) in photosynthetic tissues allows greater photochemical activity.

RESUMO O objetivo deste estudo foi avaliar o desempenho produtivo e as características morfométricas e químicas, além da digestibilidade de diferentes híbridos de milho cultivados em diferentes locais para produção de silagem. Foram cultivados quatro híbridos de milho: P2866H, P3456H, P30R50VYH e P4285YHR, em quatro locais, definidos como propriedades A; B; C e D. O híbrido P4285YHR apresentou as maiores alturas de planta e de inserção de espiga (2,72m, 1,52m, respectivamente), com altura mínima registrada, nos diferentes locais, de 2,63m e 1,42m, para altura de planta e inserção de espiga, e, por isso, apresentou o maior rendimento de biomassa fresca (78.089kg ha-1). Os valores calculados de NDT mostraram tendência muito próxima àquela observada na DISMS da planta inteira, tendo o híbrido P3456H apresentado o maior valor estimado (68,74%), e o híbrido P4285YHR o menor entre eles (65,25%). Em geral, menores concentrações de carboidratos fibrosos e lignina, maior teor de carboidratos fibrosos, juntamente com satisfatória participação de grãos na estrutura da planta, conduzem a uma maior digestibilidade da matéria seca. Híbridos com menores alturas de planta não necessariamente apresentam menores rendimentos de biomassa seca, mas híbridos de maior altura e com alta participação de colmo e folhas tendem a apresentar maior teor de aFDN e menor digestibilidade da matéria seca.

ABSTRACT The aim of this study was to evaluate the yield, morphometric and chemical characteristics, and the digestibility of various corn hybrids cultivated in different locations for silage production. Four corn hybrids were grown: P2866H, P3456H, P30R50VYH and P4285YHR, in four locations, defined as farm A; B; C and D. The hybrid P4285YHR presented the highest plant and ear insertion heights (2.72m, 1.52m respectively), with a minimum registered height of 2.63 m and 1.42 m, for plant and ear insertion height, and for that reason it presented the highest yield of fresh biomass (78,089kg ha-1). The TND values showed trend very close to that observed in the DISMS of the whole-plant, with hybrid P3456H presenting the highest estimated value (68.74%), and the hybrid P4285YHR the lowest among them (65.25%). In general, lower fibrous carbohydrates and lignin content, higher fibrous carbohydrates content, together with satisfactory grains participation in the plant structure led to a greater dry matter digestibility. Hybrids with lower plant heights do not necessarily have lower dry biomass yields, but hybrids of greater height and with high stem and leaf participation tend to have a higher aFDN content and less dry matter digestibility.

RESUMO O objetivo deste trabalho foi avaliar o efeito da substituição da silagem de sorgo por diferentes proporções de silagem de triticale no desempenho e na carcaça de novilhas Braford. A silagem de sorgo foi substituída em 0%, 30%, 60% e 100% pela silagem de triticale como fonte de volumoso na alimentação de 24 novilhas da raça Braford, em um sistema de confinamento. O período experimental total foi de 63 dias para a avaliação do consumo dos componentes da ração, a conversão alimentar e o ganho médio diário. Ao final do experimento, os animais foram abatidos e avaliados em relação às características de carcaça. A substituição da silagem de sorgo pela silagem de triticale não apresentou efeito no consumo dos componentes da ração e no ganho médio diário entre as novilhas (P>0,05). A conversão alimentar foi melhor para as novilhas que receberam menores proporções de silagem de triticale (0% e 30%) em substituição à silagem de sorgo (P<0,05). As características das carcaças foram semelhantes entre os animais independentemente da fonte de volumoso. A silagem de triticale apresenta-se como alimento alternativo à silagem de sorgo em regiões de transição climática para a terminação de novilhas de corte, proporcionando o mesmo desempenho animal e as mesmas características de carcaça.

ABSTRACT The aim of this study was to evaluate the effect of sorghum silage substitution with different proportions of triticale silage on the performance and carcass of Braford heifers. Twenty-four Braford heifers were randomly assigned to four diets where sorghum silage was replaced at 0%, 30%, 60%, and 100% for triticale silage in a feedlot system. During sixty-tree days of the experiment, the feed intake, feed ratio conversion, and average daily gain were measured. The heifers were slaughtered and the effects of the sorghum and triticale silage in carcass characteristics were evaluated. The replacement of sorghum silage with triticale silage did not affect the feed intake and average daily gain (P> 0.05). Feed gain ratio was higher for the heifers that received lower proportions of triticale silage (0% and 30%) in replace sorghum silage (P <0.05). Eye loin area and fat thickness were similar among treatments (P<0.05). Other carcass characteristics, such as slaughter live weight, dressing percentage, conformation and fat classification were similar among experimental treatments (P<0.005). Triticale silage can replace sorghum silage for finishing beef heifers in feedlot system and provides similar carcass characteristics.

RESUMO Objetivou-se avaliar o desempenho produtivo, o consumo de matéria seca, a digestibilidade aparente e o comportamento ingestivo de novilhos confinados, alimentados com silagem de milho da porção inicial de silos do tipo trincheira, conservada sob distintos tipos de vedação. Os animais foram divididos em três tratamentos, com quatro repetições: vedação convencional - polietileno tipo dupla face, com espessura de 110µm; vedação dupla face - polietileno tipo dupla face, com espessura de 200µm; e dupla vedação - polietileno tipo dupla face, com espessura de 80µm sobreposto a um filme vácuo translúcido de poliamida, com espessura de 20µm. O uso da vedação dupla face proporcionou incremento de 12,63% no ganho de peso médio diário e melhorou em 0,62 ponto percentual a conversão alimentar. A digestibilidade aparente da dieta com silagem do sistema de vedação dupla face foi 4,30% superior em relação à dieta com silagem da dupla vedação e 11,00% superior à dieta com silagem da vedação convencional. Recomenda-se a utilização tanto da vedação dupla face com polietileno de 200µm quanto da dupla vedação com polietileno tipo dupla face, com espessura de 80µm, sobreposto a um filme vácuo translúcido de poliamida com espessura de 20µm.

ABSTRACT This study aimed to evaluate the productive performance, dry matter intake, apparent digestibility and ingestive behavior of feedlot calves fed corn silage from the feed out face of trench silos with different types of sealing. The animals were divided into three treatments with four repetitions: Conventional seal - double-sided polyethylene of 110µm thickness; Double-sided seal - double-sided polyethylene of 200µm thickness; and Double seal - composed of double face polyethylene with a thickness of 80µm superimposed on a polyamide translucent vacuum film with a thickness of 20µm. The use of double face sealing provided 12.63% increase in average daily gain and improved food conversion by 0.62 percentage points. The apparent digestibility of the diet with double-face sealing system silage was 4.30% higher than the diet with double-face sealing silage and 11.00% higher than the diet with conventional sealing silage. It is recommended to use the double face sealing with 200µm polyethylene and double face sealing with 80µm thick polyethylene on top of a 20µm thick polyamide translucent vacuum film.

Abstract The combination of ethnobotanical and ecological knowledge is an important tool in indicating priority species for conservation. We sought to gather ethnobotanical knowledge on the diversity and use of woody medicinal plants in the Chapada Araripe region, assessing the real availability of woody medicinal resources in the Araripe Forests in the cerrado and carrasco areas, and indicate priority species for conservation. A total of 107 species were recorded in the ethnobotanical surveys, classified into 39 families and 83 genera, of which 92 species, 36 families and 70 genera for the cerrado areas, and 47 species, 25 families and 39 genera, for the carrasco areas. 59% were present in the phytosociological surveys for cerrado and 38% for carrascos. Species with high versatility of medicinal use did not necessarily have high local availability, and some were not recorded in the sampling. Thirteen species in cerrados and four in carrascos were indicated as conservation priorities. Use not aligned of species with the reality of the present time can indeed affect the vegetation landscape, and in a future scenario, not taking local measures to conserve protected forest resources, besides increasing the lists of local conservation priorities, can affect economic practices, increasing social and environmental conflicts.