Abstract Objective: This study aimed to investigate non-alcoholic fatty liver disease (NAFLD) occurrence and factors associated with the disease in phenylketonuria (PKU) patients undergoing exclusive dietary treatment. Method: This cross-sectional study included 101 adolescents 10 to < 20 years of age with PKU, who were undergoing exclusive dietary treatment and monitored since early diagnosis at a single reference service. Anthropometric and biochemical assessments were performed and food intake was documented, and an ultrasound diagnosis of NAFLD was established. Data were evaluated using the Student’s t-test for continuous variables, the chi-square for categorical variables, and logistic regression using the Wald chi-squared test; differences with p < 0.05 were considered to be statistically significant. Results: NAFLD was detected in 26 (25.7%) teenagers. There was no difference in prevalence between the sexes or nutritional status. The final logistic regression model revealed low sensitivity (26.1%) and high specificity (94.7%). The specificity suggested a lower likelihood of NAFLD in older adolescents, in the presence of normal or high levels of alkaline phosphatase, lower carbohydrate intake, and adequate protein and lipid intake. Conclusions: The prevalence of NAFLD in adolescents with PKU was higher than that found in healthy Brazilian adolescents and similar to that found in obese Brazilian children, suggesting a higher risk for NAFLD in patients with PKU treated exclusively by dietary modification.

Resumo Objetivou-se caracterizar o perfil de internações de crianças na rede pública dos 52 municípios do estado de Rondônia, Brasil, no período de 2008 a 2019. Trata-se de um estudo de série temporal do tipo ecológico, com dados secundários do Sistema de Informações Hospitalares. A tendência anual das internações foi apresentada por faixa etária e regional de saúde. Foi realizada regressão linear aplicando a técnica de Prais-Winsten no pacote estatístico Stata, versão 11.0. As internações por doenças gastrointestinais tiveram declínio em todas as faixas etárias, assim como pelas doenças previníveis por imunizantes entre 1 a 9 anos. As internações por doenças de pele e tecido subcutâneo foram crescentes em todas as idades, as epilepsias em idades de 1 a 9 anos e pelas doenças relacionadas ao parto e puerpério foi crescente. As regiões de saúde apresentaram perfil de internações variável, com tendência estável nas regiões Cone Sul, Madeira-Mamoré, Café, Vale do Guaporé, Vale do Jamari; e em declínio nas regiões Central e Zona da Mata. As elevadas taxas de internações por condições sensíveis à atenção primária em crianças refletem a pouca efetividade das estratégias e dos investimentos na esfera da atenção primária no estado.

Abstract This study aimed to define the profile of hospitalizations of children in public hospitals of 52 municipalities of the state of Rondônia, Brazil. We performed an ecological time series study using secondary data provided by the Hospital Information System. The annual trend of Hospitalizations was presented by age group and health region. Linear regression was performed using the Prais-Winsten technique of the statistical package Stata, version 11.0. Hospitalizations for gastrointestinal diseases were found to be decreasing in all age groups, just as those for vaccine-preventable diseases in children aged between 1 and 9 years. Hospitalizations for skin and subcutaneous tissue diseases were increasing in all ages, as well as those caused by epilepsies in children aged 1 to 9 and those caused by diseases related to childbirth and puerperium. Health regions showed a varied hospitalization profile. A stable trend was found in the Cone Sul, Madeira-Mamoré, Café, Vale do Guaporé, and Vale do Jamari regions, whereas a declining trend was found in the Central and Zona da Mata regions. The high rates of hospitalizations for ambulatory care-sensitive conditions in children show how inefficient strategies and investments in primary care have been in the state of Acre, Brazil.

ABSTRACT Iphigenia brasiliensis is a bivalve mollusk exploited as a shellfish and subsistence resource on the Brazilian coast, mainly in the north and northeast regions. Genetic (allozyme electrophoresis revealed eight gene loci) and morphological variations (multivariate morphometry of valves used 13 linear measurements of traditional and 19 Fourier coefficients of geometric morphometry) were studied, considering the geographic (445 km of the southwest tropical Atlantic), environmental (mangroves and channels of communication with the sea of three estuaries in the state of Rio de Janeiro), and temporal dimensions (over two years). I. brasiliensis showed high levels of genetic variation (the average number of alleles per locus ranged from 2.8 to 3.4, and the average heterozygosity ranged from 0.441 to 0.675). Bayesian analysis of population partitioning showed that the highest LnP(D) value was achieved for K = 3. These results indicated mixed ancestry, possibly oscillations in the dispersion dynamics among the different sampling groups, and temporal oscillations in the population sizes due to the anthropogenic influence on the studied estuaries. The results of morphological variation, inferred by the PERMANOVA from the Fourier analysis, indicated that a similar influence might occur in valves (also, the discriminant analysis showed that different groups could be consistently identified). In this sense, the studied populations may be organized in a dynamic of metapopulations. Finally, these are the first data on morphological and genetic variation of the species in the latitudinal, environmental, and temporal dimensions studied simultaneously, thus providing relevant information for the exploration, management, and conservation of this commercially important species.

Resumo Antecedentes A orientação espacial é um domínio cognitivo frequentemente comprometido em pacientes com doença de Alzheimer (DA) e pode ser uma das suas primeiras manifestações clínicas. Alguns estudos demonstraram que a integração alocêntrica com informações espaciais egocêntricas parece prejudicada nessa patologia. Não há um consenso sobre qual a melhor forma de avaliar a orientação espacial e os testes tradicionais carecem de validade ecológica; porém, recentemente, a realidade virtual (RV) proporcionou novas oportunidades para esta avaliação. Objetivos Analisar a aplicabilidade e estabilidade de uma tarefa virtual imersiva desenvolvida para avaliar a orientação espacial, o Spatial Orientation in Immersive Virtual Environment Maze Test (SOIVET-Maze) em idosos com e sem comprometimento cognitivo leve. Métodos Quarenta e três idosos foram incluídos no estudo, 24 sem comprometimento cognitivo e 19 com comprometimento cognitivo leve. A aplicabilidade foi avaliada pelo Witmer and Singer Sense of Presence Questionnaire e um questionário para eventos adversos de cybersickness. Para avaliar a estabilidade, os participantes foram avaliados 2 vezes com intervalo de 7 a 14 dias, e o coeficiente de correlação intraclasse foi calculado entre as visitas. O teste t ou o teste de Mann-Whitney foi utilizado para comparar a aplicabilidade e estabilidade entre os grupos. Resultados Não houve diferença significativa entre os grupos quanto à aplicabilidade. Uma forte correlação entre o primeiro e o segundo dia de teste foi encontrada no grupo de comprometimento cognitivo leve. Conclusão A tarefa SOIVET-Maze apresentou excelente aplicabilidade e boa estabilidade, favorecendo sua aplicação clínica para avaliação da orientação espacial em idosos.

Abstract Background Spatial orientation is a cognitive domain frequently compromised in patients with Alzheimer disease (AD) and may be one of its first clinical manifestations. Some studies have shown that allocentric integration with egocentric spatial information seems to be impaired in this pathology. There is no consensus on how best to assess spatial orientation and traditional tests lack ecological validity, but, recently, virtual reality (VR) has provided new opportunities for this assessment. Objectives To analyze the applicability and stability of an immersive virtual task developed to assess spatial orientation, the Spatial Orientation in Immersive Virtual Environment Maze Test (SOIVET-Maze) in older adults with and without mild cognitive impairment. Methods Forty-three older adults were included in the study, 24 without cognitive impairment and 19 with mild cognitive impairment. Applicability was assessed by the Witmer and Singer Sense of Presence Questionnaire and a questionnaire for adverse events of cybersickness. To assess stability, participants were assessed twice with an interval of 7 to 14 days, and the intraclass correlation coefficient was calculated between visits. The t test or the Mann-Whitney test was used to compare applicability and stability between groups. Results There was no significant difference between the groups regarding applicability. A strong correlation between the first and second day of testing was found in the mild cognitive impairment group. Conclusion The SOIVET-Maze task showed excellent applicability and good stability, favoring its clinical application for the evaluation of spatial orientation in older adults.

Resumo O objetivo deste trabalho foi avaliar as respostas agronômicas de videiras 'BRS Vitória' submetidas à nutribioirrigação com e sem adubação convencional. Utilizou-se o delineamento inteiramente casualizado, com três tratamentos e 18 repetições. Os tratamentos foram: TC, adubação e irrigação convencionais; TNC, nutribioirrigação e adubação; e TN, apenas nutribioirrigação. Foram analisadas as seguintes variáveis: diâmetros do porta-enxerto e do enxerto; crescimento da planta; número de botões laterais; teores de amido na raiz, na folha, no pecíolo e nas gemas; número por planta, comprimento, circunferência e massa fresca dos cachos; número por cacho, comprimento, diâmetro, massa fresca, sólidos solúveis, acidez titulável e pH das frutas; produção; e teores de macro e micronutrientes nas folhas. De 100 a 150 dias após o transplantio (DAT), os diâmetros do portaenxerto e do enxerto foram similares, tendo aumentando de 250 a 300 DAT no TC. O maior teor de amido na raiz foi de 7,19% no TN aos 150 DAT e de 37,35% no TNC aos 300 DAT. As plantas no TNC apresentaram os melhores resultados para número por planta e massa fresca dos cachos, o que resultou em produção 22% superior à obtida nos demais tratamentos. A videira 'BRS Vitória' apresenta desempenho agronômico satisfatório quando submetida à nutribioirrigação.

Abstract The objective of this work was to evaluate the agronomic responses of 'BRS Vitória' grapevines under bio-fertigation with and without conventional soil fertilizer. A completely randomized design was used, with three treatments and 18 replicates. The treatments were: CFI, conventional soil fertilizer and irrigation; BF+CF, bio-fertigation and conventional fertilizer; and BF, only bio-fertigation. The following variables were evaluated: graft and rootstock diameters; plant growth; number of lateral buds; root, leaf, petiole, and gem starch contents; bunch number per plant, length, circumference, and fresh weight; berry number per bunch, length, diameter, fresh weight, soluble solid contents, titratable acidity, and pH; yield; and leaf macro- and micronutrient contents. From 100 to 150 days after transplanting (DAT), rootstock and graft diameters were similar, increasing from 250 to 300 DAT in the CFI treatment. The highest root starch content was 7.19% in BF at 150 DAT and 37.35% in BF+CF at 300 DAT. The plants in BF+CF showed the best results for bunch number per plant and fresh weight, resulting in a fruit yield 22% higher than that obtained in the other treatments. 'BRS-Vitória' grapevines show a satisfactory agronomic performance when bio-fertigated.

Abstract Introduction Febrile neutropenia (FN) is a serious complication of cancer chemotherapy. The present study aimed to identify risk factors for documented infection in pediatric patients with FN and cancer. Methods This prospective cohort study included patients under 18 years from 2016 to 2018. Infection was defined according to the Centers for Disease Control and Prevention criteria. Results A total of 172 febrile neutropenic episodes were evaluated. From univariate analysis, the risk factors were: female gender; monocyte count < 100 cell/mm³, platelets < 50,000, C-reactive protein (CRP) > 90 mg/dl and hemoglobin < 7mg/dl at the onset of an episode; two or more episodes of FN, and; fever onset; positive blood culture at the fever onset. Independent risk factors according to the multivariate analysis were: CRP at the onset of a febrile episode > 90mg/dl, fever onset and first blood culture with a positive result. The lowest probability of infection was related to first episode and to platelets > 50,000 at the onset of fever. Conclusion A CRP > 90 at the onset of a febrile episode, platelets < 50,000, second episode or more, first fever episode during hospitalization and positive first blood culture were found to be associated with a higher risk of infection and they could be useful for the establishment of risk scores for infection in neutropenic children.

Abstract The aim of this study was to investigate uterine involution using ultrasonography techniques during postpartum. Postpartum ultrasonography evaluation (B-mode, color Doppler and Acoustic Radiation Force Impulse elastography) of the uterus was performed by transabdominal approach at immediate after birth and sequentially every 48 hours, during 30 days. The uterine echotexture did not present significant variations (P >0.05) being homogeneous in most evaluations; echogenicity of the uterus increased along the evaluation period (P =0.0452). Progressive and remarkable decrease of the total uterine diameter (UD) were observed (P <0.0001), especially during the first days postpartum. The thickness of uterine wall gradually decreased, as well the endometrial, myometrium and lumen diameters (P <0.0001). Uterine blood flow was assessed by Doppler and decreased during postpartum period, being significantly lower (P=0.0225) on the 30th day of postpartum. Uterine parenchyma presented as homogeneous dark areas (not deformable) on qualitative ultrasound elastography and the means shear velocity values of the uterine wall on quantitative elastography did not differ. This is the first study that evaluate the stiffness of uterine wall in healthy ewes, providing baseline data about quantitative and qualitative stiffness of the normal uterus, and it may be a useful tool for early diagnosis of uterine alterations during the postpartum period, using the reference parameter established for the assessment of uterine integrity during postpartum period.

Developing biomaterials for tissue regeneration is a promising alternative for the recovery of various tissues, including bone. Atorvastatin (ATV) has a series of beneficial effects which includes bone anabolism, vasodilating, and anti-inflammatory actions. The main objective of this work was to produce and characterize polycaprolactone (PCL) matrices incorporated with ATV. Samples were prepared by the solvent casting technique. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), Fourier transform infrared spectrometry (FTIR), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and in vitro release studies were performed. FTIR analysis showed that no chemical bonds were formed between PCL and ATV. SEM analysis showed that the amount of ATV affects sample morphology. According to XRD and thermal analysis, the main ATV characteristics were maintained. The studies showed that PCL/ATV samples release the drug in a prolonged way since its release reaches around 50% after 15000 minutes of analysis and the model that showed the best fit for the studied matrices was the Higuchi model, with a correlation coefficient above 0.95.

RESUMO Objetivo: O objetivo deste estudo centrou-se na elaboração e validação de uma escala de percepção estética organizacional (AESCATScale) para ser usada na compreensão das percepções dos indivíduos sobre a vida organizacional. Metodologia: Para tanto, realizamos revisão bibliográfica, entrevistas exploratórias, aplicação de surveys e técnicas de análise multivariada. A escala foi validada por meio de aplicação com professores de ensino superior Resultados: Nossos resultados consistiram em um modelo de construto multidimensional para percepção da estética organizacional (AESCATScale), com sete dimensões e vinte itens. Conforme a análise, o construto se mostrou consistente e pode ser tomado como base para evoluções posteriores do estudo. Limitações/implicações da pesquisa: Destacamos três limitações peculiares à pesquisa: a) o caráter subjetivo do tema, b) a falta de compreensão de algumas categorias pelos respondentes e c) a amostra utilizada foi escolhida por sua acessibilidade e por ter sido restrita a professores universitários de um único estado do Brasil. Implicações práticas: A AESCATScale pode revelar a lógica sensível subjacente a várias práticas organizacionais no local de trabalho de um ponto de vista sensível. Além disso, pode ser uma ferramenta útil para auxiliar na tomada de decisão de um gerente em situações de mudança. Originalidade/valor: Este estudo apresenta uma abordagem diferenciada para a gestão organizacional que às vezes pode ser perdida devido à sua natureza abstrata. Portanto, apresenta uma ferramenta de pesquisa inovadora que pode ser usada tanto em ambientes corporativos quanto acadêmicos.

ABSTRACT Purpose: The aim of this study focused on the elaboration and validation of an organizational aesthetic perception scale (AESCATScale) to be used in understanding individuals’ perceptions of organizational life. Design/methodology/approach: We carried out a literature review, exploratory interviews, two separate surveys, and multivariate analyses. The scale was validated through an application with a large sample of college professors. Findings: Our outcomes consisted of a multidimensional construct model for the perception of organizational aesthetics (AESCATScale), with seven dimensions and 20 items. According to our analysis, the organizational aesthetics construct is consistent and may be the basis for future studies on the subject. Research limitations/implications: We highlight three peculiar limitations to the research: a) the subjective nature of the theme, b) the lack of comprehension of some categories by respondents and c) the sample used was chosen for its accessibility and to have been restricted to college professors of a single state in Brazil. Practical implications: The AESCATScale may reveal the sensitive logic underlying several organizational practices in the workplace based on a sensitive point of view. Also, it can be a valuable tool to aid in a manager’s decision-making in situations of change. Originality/value: This study introduces a differentiated approach to organizational management that can sometimes be missed due to its abstract nature. Therefore, it introduces a novelty research tool that can be used in corporate and academic environments.

Congenital anatomical variations of the terminal aorta are rare. Given the increasing number of endovascular and laparoscopic procedures, such variations are likely to assume greater clinical significance. A 15-year-old male sustained a pelvic vascular injury following a stab to the left gluteus. Computed tomographic angiography and digital subtraction angiography demonstrated a left superior gluteal artery pseudoaneurysm and absence of the common iliac arteries consistent with congenital quadrifurcation of the terminal aorta. The patient was subsequently treated with endovascular coil embolisation with a good angiographic and clinical outcome. CONTRIBUTION: Terminal aortic variants are rare and given the increasing number of interventional endovascular procedures performed in the aorta, an awareness of the potential anatomical configurations of the distal aortic branches is of increasing relevance. The authors describe the imaging findings of one such anatomical variant.

Resumo Objetivo Avaliar, a partir do discurso de profissionais da Atenção Básica, como o uso da estratégia Audit and Feedback contribuiu para geração de tensão por mudança na implementação de apoio matricial em um município paulista de médio porte. Métodos Estudo qualitativo, realizado por meio da análise da transcrição de Grupos de Apreciação Partilhada que empregaram a estratégia Audit and Feedback junto a cinco equipes de Atenção Básica em um município paulista de médio porte entre dezembro de 2019 e março de 2020. Para análise dos dados foi empregada análise de conteúdo que utilizou como categorias previamente definidas os desfechos de implementação: aceitabilidade, adequação e adoção, entendidos como principais desfechos relacionados à tensão por mudanças. Resultados As falas dos profissionais que participaram dos grupos em que foi empregada a estratégia Audit and Feedback permitiram identificar a geração de tensão por mudança produzida a partir dos dados que lhe foram apresentados. Indicativos de aceitabilidade, adequação e adoção em relação ao apoio matricial foram evidenciados, sugerindo assim a contribuição da estratégia empregada para o sucesso da implementação. Conclusão A estratégia Audit and Feedback se mostrou efetiva na geração de tensão por mudança, favorecendo assim o reconhecimento da necessidade da intervenção e consequentemente facilitando a sua implementação.

Abstract Objective Based on the discourse of Primary Care professionals, to assess how the use of the Audit and Feedback strategy contributed to the generate tension for change in the implementation of matrix support in a medium-sized city in São Paulo. Methods Qualitative study conducted by analyzing the transcript of Shared Appreciation Groups that used the Audit and Feedback strategy with five Primary Care teams in a medium-sized city in São Paulo between December 2019 and March 2020. Content analysis was used in data analysis. The implementation outcomes: acceptability, adequacy and adoption, understood as the main outcomes related to the tension for change, were previously defined as categories. Results The speeches of professionals who participated in the groups in which the Audit and Feedback strategy was used made it possible to identify the generation of tension for change produced from data presented to them. Indications of acceptability, adequacy and adoption in relation to the matrix support were evidenced, thereby suggesting the contribution of the strategy employed to the success of the implementation. Conclusion The Audit and Feedback strategy proved to be effective in generating tension for change, thereby favoring the recognition of the need for intervention and consequently facilitating its implementation.

Resumen Objetivo Evaluar, a partir del discurso de profesionales de la Atención Básica, de qué forma el uso de la estrategia Audit and Feedback contribuyó para la generación de tensión por cambio en la implementación de apoyo matricial en un municipio del estado de São Paulo de tamaño mediano. Métodos Estudio cualitativo, realizado por medio del análisis de la transcripción de Grupos de Apreciación Compartida que utilizaron la estrategia Audit and Feedback con cinco equipos de Atención Básica en un municipio del estado de São Paulo de tamaño mediano entre diciembre de 2019 y marzo de 2020. Para el análisis de los datos se empleó el análisis de contenido que utilizó como categorías previamente definidas los desenlaces de implementación: aceptabilidad, adecuación y adopción, entendidos como principales desenlaces relacionados con la tensión por cambios. Resultados Los relatos de los profesionales que participaron de los grupos en los que se empleó la estrategia Audit and Feedback permitieron identificar la generación de tensión por cambio producida a partir de los datos que les presentaron. Se evidenciaron indicativos de aceptabilidad, adecuación y de adopción en relación con el apoyo matricial, lo que sugiere la contribución de la estrategia empleada para el éxito de la implementación. Conclusión La estrategia Audit and Feedback demostró ser efectiva en la generación de tensión por cambio, lo que favorece el reconocimiento de la necesidad de la intervención y, como consecuencia, facilita su implementación.

Abstract Objectives Evidence suggests that ketamine’s influence on brain-derived neurotrophic factor (BDNF) might be involved in its mechanism of rapid antidepressant action. We aimed to evaluate the differential impact of ketamine and esketamine on serum BDNF levels and its association with response patterns in treatment-resistant depression (TRD). Methods Participants (n = 53) are from a randomized, double-blind clinical trial comparing the efficacy of single-dose ketamine (0.5mg/kg, n = 27) and esketamine (0.25mg/kg, n = 26) in TRD. Depression severity was assessed before and 24 hours, 72 hours, and 7 days after the intervention, using the Montgomery-Åsberg Depression Rating Scale (MADRS). Blood samples were collected before infusion, 24 hours, and 7 days afterwards. Results There were no significant changes in BDNF levels at post-infusion evaluation points, and no difference in BDNF levels comparing ketamine and esketamine. Both drugs exhibited similar therapeutic effect. There was no association between BDNF levels and response to treatment or severity of depressive symptoms. Conclusion There was no significant treatment impact on BDNF serum levels – neither with ketamine nor esketamine – despite therapeutic response. These results suggest that ketamine or esketamine intervention for TRD has no impact on BDNF levels measured at 24 hours and 7 days after the infusion. This clinical trial is registered on the Japan Primary Registries Network: UMIN000032355.

Resumo Objetivo: Identificar na literatura nacional e internacional o uso da realidade virtual no desenvolvimento de habilidades manuais de crianças com paralisia cerebral. Métodos: Revisão sistemática realizada nas bases de dados United States National Library of Medicine (PubMed), Portal de Periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e no Sistema Online de Busca e Análise de Literatura Médica (Ovid Medline) utilizando as palavras-chave “paralisia cerebral”, “realidade virtual”, “terapia ocupacional”, “criança”, “atividades diárias/ atividades cotidianas”, em inglês e português. A qualidade metodológica dos artigos selecionados foi avaliada pela Physiotherapy Evidence Database (escala PEDro). Resultados: Foram selecionados 228 estudos que incluíam crianças com paralisia cerebral em tratamento com exposição à realidade virtual para a melhora da função manual nas atividades diárias, sendo excluídos os que estavam fora da temática, os incompletos e os duplicados. Três juízes conduziram o processo de seleção dos trabalhos, incluindo 14 artigos na análise. Conclusões: Os achados sugerem que a terapia com realidade virtual tem contribuído para a melhora na função manual de crianças com paralisia cerebral, constituindo-se em recurso útil de intervenção coadjuvante potencializadora das terapias tradicionais.

Abstract Objective: To identify in national and international literature the use of virtual reality to develop manual skills of children with cerebral palsy. Methods: This is a systematic review carried out in the PubMed database, Portal de Periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), and the Online System for Search and Analysis of Medical Literature (Ovid Medline) using the keywords “cerebral palsy”, “virtual reality”, “occupational therapy”, “child”, “daily activities/activities of daily living”, in English and in Portuguese. The selected articles had their methodological quality evaluated through the Physiotherapy Evidence Database (PEDro scale). Results: 228 studies were selected, as they included children with cerebral palsy undergoing treatment with exposure to virtual reality to improve manual function in daily activities. Studies on other themes, incomplete, and duplicated reviews were excluded. Three evaluators conducted the study selection process and included 14 articles in the analysis. Conclusions: The findings suggest that virtual reality therapy has contributed to an improvement in the manual function of children with cerebral palsy, constituting a useful resource for a supporting intervention to enhance traditional therapies.

ABSTRACT Introduction: The exponential growth of telehealth services during the COVID-19 pandemic led to the implementation of a telemedicine care service in a tertiary university pediatric hospital. It brought the need to develop a training aimed at remote care within the pediatric emergency rotation program. Objective: To describe the implementation of a telemedicine training for pediatric residents and present the preliminary results. Methods: Descriptive prospective study (pre and post), with 40 resident physicians of the first year of pediatrics. Reaction Assessments were applied before and after training, in addition to a resident physician perception questionnaire at the end of the training. Results: There was a significant difference in the resident’s perception of experience and safety after initial training. Most rated the proposal as good or excellent, considered teaching telemedicine relevant and that this experience contributed to their learning on the subject. Conclusion: This study describes an innovative proposal for training in telemedicine. The preliminary results were encouraging, demonstrating the program’s potential in training future pediatricians.

Resumo: Introdução: A discussão sobre profissionalismo médico é relativamente recente e o tema tem se tornado cada vez mais frequente em publicações sobre educação médica. Trata-se de conceito complexo, pois, como uma competência, envolve um conjunto de atributos, conhecimentos, habilidades e comportamentos que são influenciados pelos contextos político e sociocultural. Várias estratégias foram propostas para sua avaliação, mas não se identificou na literatura nenhum instrumento específico validado para o Brasil. Objetivo: Este estudo teve como objetivo realizar a tradução e adaptação transcultural de um questionário para avaliação de profissionalismo médico. Método: Realizaram-se a tradução e a adaptação transcultural do The Penn State College of Medicine Professionalism Questionnaire. A confiabilidade e a consistência interna foram avaliadas pelo alfa de Cronbach. Resultado: A tradução e a adaptação transcultural resultaram em questionário com 37 itens com boa validade semântica, idiomática, experiencial e conceitual. O alfa de Cronbach (0,886) mostrou alta confiabilidade. Conclusão: A versão final do instrumento mostrou boa validade, consistência interna e confiabilidade. Ele pode ser utilizado tanto na educação continuada de profissionais já formados como na educação médica, como ferramenta de reflexão e avaliação.

Abstract: Introduction: The discussion about medical professionalism is relatively recent and the topic has become increasingly frequent in publications on medical education. It is a complex concept, since it is a competence that involves a set of attributes, knowledge, skills, and behaviors that are influenced by the political and socio-cultural context. Several strategies have been proposed for its assessment, but no specific instrument validated for Brazilian Portuguese was identified in the literature. Objective: To translate and do the transcultural adaptation of a questionnaire for assessing medical professionalism. Methods: The Penn State College of Medicine Professionalism Questionnaire was translated and cross-culturally adapted according to recommendations found in the literature. Reliability and internal consistency were assessed by Cronbach’s alpha. Results: The translation and cultural adaptation resulted in a questionnaire with 37 items with good semantic, idiomatic, experiential, and conceptual validity. Cronbach’s alpha (0.886) showed good reliability. Conclusions: The final instrument showed good validity, internal consistency, and reliability. It can be used both in the continuing education of physicians and in medical education, as a tool for reflection and assessment.