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1.
Nonlinear analysis of plane frames considering hyperelastic models through the finite element positional method
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Santos, Leandro dos
; Maciel, Daniel Nelson
; Barros, Rodrigo
; Nascimento Neto, Joel Araújo do
; Silva Filho, José Neres da
.
Abstract Computational mechanics has become an essential tool in engineering, just as the use of hyperelastic materials has seen remarkable growth in everyday applications. Therefore, it is fundamental to study hyperelastic models that represent the behavior of these materials, such as elastomers and polymers. With that in mind, the Mooney-Rivlin, Neo-Hookean, Ogden, and Yeoh models were implemented in a computational code in FORTRAN using the Positional Finite Element Method with Reissner kinematics and the Newton-Raphson method for nonlinear analysis of plane frames with samples of elastomers added with different percentages of carbon black. Ultimately, it was concluded that the Yeoh and Ogden models presented coherent values and that the use of the formulation for nonlinear analysis of plane frame performs well after the modifications proposed by this work. These modifications consisted of adding the first and second strain invariants of the simple shear formulation to include the consideration of distortion in the specific strain energy of hyperelastic models. engineering applications Therefore polymers mind MooneyRivlin, MooneyRivlin Mooney Rivlin, Rivlin Mooney-Rivlin NeoHookean, NeoHookean Neo Hookean, Hookean Neo-Hookean NewtonRaphson Newton Raphson black Ultimately work
2.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
3.
Genetic variant in the AGT gene (rs699-GG) is associated with severe COVID-19 in Brazilian patients rs699GG rsGG rs699 GG rs (rs699-GG COVID19 COVID 19 COVID-1 rs69 COVID1 1 COVID- rs6
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FARIAS, PABLO C.S.
; CABRAL, LEANDRO P.
; NEVES, PATRÍCIA A.F.
; JANUÁRIO, CAIO A.B.
; CORDEIRO, BEATRIZ M.
; SILVA JÚNIOR, WILSON J. DA
; BASEGGIO, CAROLINA
; PAIVA JÚNIOR, SÉRGIO S.L.
; ARAÚJO, PAULO S.R. DE
; LORENA, VIRGÍNIA MARIA B. DE
; BALBINO, VALDIR Q.
; LIMA NETO, REGINALDO G.
.
Anais da Academia Brasileira de Ciências
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Abstract The COVID-19 pandemic has been the largest pandemic of the past century, and various genetic factors have played a significant role in this context. This study aimed to analyze the frequency and association between specific SNPs rs3806268 (NLRP3), rs4925543 (NLRP3), rs12150220 (NLRP1), rs455060 (NLRC4), rs699 (AGT), rs1137101 (LEPR), and rs1801133 (MTHFR) and severe/critical outcomes in Brazilian patients with COVID-19. A total of 100 patients were included in the study, comprising 66 cases and 34 controls. DNA was extracted, sequenced, and genotyped via next-generation sequencing (NGS). For non-parametric data, the Mann-Whitney and Kruskal-Wallis tests were used. Fisher’s test and multivariate logistic regression, considering AIC and BIC criteria, were employed for risk analysis. Odds Ratios (OR) were calculated, with significance set at p<0.05. Among the seven evaluated SNPs, only rs699-GG (AGT) (OR=8.07; p=0.04) was significantly associated with an increased risk of developing severe/critical COVID-19. Moreover, a borderline protective association was noted between rs1801133-GA (MTHFR) and the disease, although lacking statistical significance. In conclusion, the SNP rs699-GG (AGT) was associated with an increased risk of severe/critical COVID-19. COVID19 COVID 19 COVID-1 century context rs rs380626 NLRP3, NLRP3 NLRP , (NLRP3) rs492554 rs1215022 NLRP1, NLRP1 (NLRP1) rs45506 NLRC4, NLRC4 NLRC (NLRC4) rs69 AGT, AGT rs113710 LEPR, LEPR (LEPR) rs180113 MTHFR (MTHFR severecritical severe critical COVID19. 19. 10 6 3 controls extracted sequenced nextgeneration next generation NGS. NGS . (NGS) nonparametric non parametric data MannWhitney Mann Whitney KruskalWallis Kruskal Wallis used Fishers Fisher s regression criteria analysis OR (OR calculated p005 p 0 05 p<0.05 rs699GG rsGG GG (AGT OR=8.07 OR807 8 07 (OR=8.07 p=0.04 p004 04 Moreover rs1801133GA rsGA GA disease conclusion COVID1 1 COVID- rs38062 (NLRP3 rs49255 rs121502 (NLRP1 rs4550 (NLRC4 rs6 rs11371 (LEPR rs18011 (NGS p00 p<0.0 OR=8.0 OR80 (OR=8.0 p=0.0 rs3806 (NLRP rs4925 rs12150 rs455 (NLRC rs1137 rs1801 p0 p<0. OR=8. OR8 (OR=8. p=0. rs380 rs492 rs1215 rs45 rs113 rs180 p<0 OR=8 (OR=8 p=0 rs38 rs49 rs121 rs4 rs11 rs18 p< OR= (OR= p= rs3 rs12 rs1
4.
Intrinsically Disordered Malaria Antigens: An Overview of Structures, Dynamics and Molecular Simulation Opportunities Antigens Structures
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Journal of the Brazilian Chemical Society
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The proteome of Plasmodium falciparum (Pf) is abundant in intrinsically disordered proteins (IDPs). Their important roles in the malaria life cycle and the limitations of experimental and computational methods to study this class of proteins hinder the development of antimalarial drugs. At the same time, the growing interest in IDPs and theoretical tools suggest a path for their classification and functional understanding: searching databases with experimental notes and predictions of protein disorder, developing force fields to describe protein flexibility, and using molecular dynamics enhanced sampling techniques to properly sample the IDP conformational diversity. This review discusses possibilities of exploration of Pf’s IDPs and their availability in disordered-protein databases to foster molecular modeling studies. The large percentage of intrinsic disorder present in many antigens and their ability to interact with different targets, make these proteins a major class of interest in the area of drug and vaccine development. Pf (Pf IDPs. . (IDPs) drugs time understanding flexibility diversity Pfs s disorderedprotein studies targets (IDPs
5.
Characterization of acquisition of physiological quality in soybean seeds from desiccated plants
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Cardoso, Carolina Pereira
; Perissato, Samara Moreira
; Bianchi, Leandro
; Ribeiro, Mariana
; Chamma, Larissa
; Silva, Edvaldo Aparecido Amaral da
.
ABSTRACT: Desiccation interrupts the acquisition of physiological quality in soybean seeds, as this quality peaks at R9. However, this interruption can be mitigated by the stage in which herbicide is applied and which herbicide is used. The aim of this study was to characterize the acquisition of physiological quality in soybean seeds from plants desiccated by herbicides at different stages. A completely randomized experimental design was used in a 3×6 factorial arrangement, consisting of three phenological stages (R6, R7.1, R7.3) and six different desiccant treatments (Diquat 1.5 L.ha-1; Glufosinate 1.5 L.ha-1 and 2.0 L.ha-1; Diquat 1.0 L.ha-1 + Glufosinate 1.0 L.ha-1; Saflufenacil 140 g.ha1 + Glufosinate 1.0 L.ha-1; and Saflufenacil 140 g.ha-1 + Diquat 1.0 L.ha-1), with four replications. The following evaluations were made: desiccation rate, germination, desiccation tolerance (DT), longevity (P50), viability after one year of storage, and thousand seed weight. Seeds are able to germinate and have DT when plant desiccation through application of Diquat, Diquat + Glufosinate, Saflufenacil + Diquat, and Saflufenacil + Glufosinate occurs at R6, and for Glufosinate, at R7.1. The use of Diquat + Glufosinate and their combination with Saflufenacil showed less impact on acquisition of soybean seed longevity, which was better when application was made at R7.3. ABSTRACT R9 R However 36 3 6 3× arrangement R6 (R6 R71 R7 1 R7.1 R7.3 R73 15 5 1. L.ha1 Lha1 Lha L.ha L ha L.ha- 20 2 0 2. 10 14 gha1 gha g ha1 g.ha g.ha- L.ha1, , L.ha-1) replications rate germination DT, (DT) P50, P50 P (P50) storage weight (R R7. (DT P5 (P50 (P5 (P
RESUMO: A dessecação interrompe a aquisição da qualidade fisiológica de sementes de soja, que atinge seu máximo em R9. Contudo, isto pode ser mitigado pelo estádio de aplicação e o herbicida utilizado. Objetivou-se caracterizar a aquisição da qualidade fisiológica de sementes de soja de plantas dessecadas por herbicidas em estádios distintos. O delineamento experimental foi inteiramente casualizado em esquema fatorial 3X6, sendo três estádios fenológicos (R6, R7.1, R7.3) e seis aplicações de dessecantes (Diquat 1,5 L.ha-1; Glufosinato 1,5 L.ha-1 e 2 L.ha-1; Diquat 1,0 L.ha-1 + Glufosinato 1,0 L.ha-1; Saflufenacil 140 g.ha-1 + Glufosinato 1,0 L.ha-1; e Saflufenacil 140 g.ha-1 + Diquat 1,0 L.ha-1), com quatro repetições. Avaliaram-se: taxa de dessecação, germinação, tolerância à dessecação (DT), longevidade (P50), viabilidade após um ano de armazenamento e peso de mil sementes. A aquisição da germinação e DT de sementes de plantas dessecadas por Diquat, Diquat+Glufosinato, Saflufenacil+Diquat e Saflufenacil+Glufosinato ocorre quando a aplicação é feita em R6, e para Glufosinato, em R7.1. O uso de de Diquat + Glufosinato e a combinação destes com Saflufenacil apresentou menor impacto na aquisição da longevidade de sementes de soja, sendo maior quando aplicados em R7.3. RESUMO R9 R Contudo utilizado Objetivouse Objetivou se distintos 3X6 X R6 (R6 R71 R7 1 R7.1 R7.3 R73 3 15 5 1, L.ha1 Lha1 Lha L.ha L ha L.ha- 10 0 14 g.ha1 gha1 gha g.ha g g.ha- L.ha1, , L.ha-1) repetições Avaliaramse Avaliaram Avaliaram-se DT, (DT) P50, P50 P (P50) DiquatGlufosinato Diquat+Glufosinato SaflufenacilDiquat SaflufenacilGlufosinato 3X (R R7. ha1 (DT P5 (P50 (P5 (P
6.
A Importância da Reconstituição do Corpo de Doadores de Órgãos e Tecidos: um Olhar Sobre a Dignidade Humana Tecidos
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Corsi, Carlos Alexandre Curylofo
; Assunção-Luiz, Alan Vinicius
; Monteiro-Silva, Leonardo
; Scarpelini, Katia Carmen Gabriel
; Bento, Rodolfo Leandro
; Ribeiro, Mayara Segundo
; Garcia, Flávio Luis
; Martins, Luís Gustavo Gazoni
.
ABSTRACT Introduction: Family refusal to authorize the donation of human organs and tissues has remained high over the years. Among the many reasons for not donating, we highlight the lack of information about the process and the family’s lack of knowledge about the donor’s wishes in life, as well as other issues, such as the appearance of the donor’s body after donation. In this sense, it is necessary to bring to light the aspects that permeate the concepts of death, human dignity, and care for the donor’s image, especially in the case of tissue donors, where the removal may be more noticeable. Objectives: An integrative literature review (ILR) was carried out, seeking to highlight gaps and characterize the process of donating human organs and tissues, with a focus on the reconstruction of the donor’s body and human dignity. In addition, the aim was to describe the experience of a professional from a human tissue bank (BTH). Methods: Using the PICO strategy, the study’s guiding question was drawn up following an IR carried out over the last 10 years, operationalized by controlled descriptors in the SciELO, LILACS, Google Scholar, and PubMed databases. In addition to the search, an experience report was described on the techniques used to reconstruct the donor’s body after the tissues used by a BTH located in the interior of the state of São Paulo were harvested. Results: Nine specific studies were found on donation and the use of prostheses to reconstruct donated areas. The results show the reasons for family refusal, as well as the care taken by the technical teams in reconstructing donors’ bodies. The family’s concern about the donor’s aesthetic situation influences acceptance for donation, so it is necessary to invest in the safety and quality of the services provided by BTH to reduce family refusal for donation. Conclusion: Clear communication and the safety of the processes involved in the procurement of human organs and tissues proved to be the best way to facilitate donation and could thus increase donations. Introduction years familys s donors donor life issues sense death dignity image noticeable Objectives ILR (ILR BTH. . (BTH) Methods strategy studys study 1 SciELO LILACS Scholar databases search harvested Results areas bodies Conclusion donations (BTH
RESUMO Introdução: A negativa familiar para autorização da doação de órgãos e tecidos humanos mantém-se elevada ao longo dos anos. Dentre as muitas causas de não efetivação da doação, destacam-se a falta de informação sobre o processo e o desconhecimento da família sobre o desejo do doador em vida, além de outras questões, como a aparência do corpo do doador após a captação. Nesse sentido, torna-se necessário trazer à luz da discussão os aspectos que permeiam os conceitos de morte, dignidade humana e zelo pela imagem do doador, principalmente no caso de doadores de tecidos, nos quais a retirada pode apresentar-se mais perceptível. Objetivos: Realizou-se uma revisão integrativa da literatura (RI), buscando evidenciar lacunas e caracterizar o processo da doação de órgãos e tecidos humanos, com foco na reconstrução do corpo do doador e na dignidade humana. Em complemento, também se propôs descrever um relato de experiência de um profissional de um banco de tecidos humanos (BTH). Métodos: Por meio da estratégia PICO, elaborou-se a questão norteadora do estudo, após a RI realizada nos últimos 10 anos, operacionalizada por descritores controlados nas bases de dados SciELO, LILACS, Google Acadêmico e PubMed. Adicionado à busca, foi descrito um relato de experiência referente às técnicas de reconstrução do corpo do doador após a captação dos tecidos utilizados por um BTH localizado no interior do estado de São Paulo. Resultados: Foram encontrados nove estudos específicos sobre doação e utilização de próteses para reconstrução de áreas doadas. Os resultados demonstram os motivos que envolvem a recusa familiar, assim como o cuidado que as equipes técnicas têm na reconstituição do corpo dos doadores. A preocupação da família em relação à situação estética do doador influencia a aceitação para doação, portanto, torna-se necessário investir na seguridade e na qualidade dos serviços prestados pelos BTH, a fim de diminuir a recusa familiar para doação. Conclusão: A comunicação clara e a seguridade dos processos que envolvem a captação de órgãos e tecidos humanos mostraram-se o melhor caminho para facilitar a doação, podendo, assim, aumentar as doações. Introdução mantémse mantém anos destacamse destacam vida questões sentido tornase torna morte apresentarse apresentar perceptível Objetivos Realizouse Realizou RI, , (RI) complemento BTH. . (BTH) Métodos PICO elaborouse elaborou estudo 1 SciELO LILACS PubMed busca Paulo Resultados doadas portanto Conclusão mostraramse mostraram podendo doações (RI (BTH
7.
Brazilian Psychiatric Association treatment guidelines for generalized anxiety disorder: perspectives on pharmacological and psychotherapeutic approaches disorder
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Baldaçara, Leonardo
; Paschoal, Ana Beatriz
; Pinto, Aldo Felipe
; Loureiro, Fabiano Franca
; Antonio, Luiz Antonio Vesco Gaiotto
; Veiga, Diogo de Lacerda
; Almeida, Thales Marcon
; dos Santos, Diogo Cesar
; Malloy-Diniz, Leandro Fernandes
; de Mello, Marcelo Feijó
; de Mello, Andrea Feijó
; Sanches, Marsal
; Gandarela, Lucas Marques
; Bernik, Márcio Antonini
; Nardi, Antonio E.
; da Silva, Antônio Geraldo
; Uchida, Ricardo R.
.
Generalized anxiety disorder is a highly prevalent mental disorder. Previous data indicate that more than 18 million Brazilians suffer from this condition. Traditionally, generalized anxiety disorder has been considered a mild mental health disorder, despite its links to lower life expectancy, cardiovascular disease, and suicide. The aim of this article is to combine elements of systematic and critical reviews to produce a synthesis of the best evidence about generalized anxiety disorder treatment. Systematic reviews, meta-analyses, and randomized controlled trials were included. The descriptor used in the search was “generalized anxiety disorder,” which resulted in 4,860 articles and seven other studies, of which 59 were selected. Antidepressants and benzodiazepines were indicated, as was pregabalin, and atypical antipsychotics, such as quetiapine, have been studied. Individual cognitive behavior therapy (third wave) has proven effective. There is extensive literature on many effective treatments for generalized anxiety disorder. The present review summarizes the therapeutic possibilities, emphasizing those available in Brazil. Further studies are needed to compare other available medications, assess psychotherapies and new treatments in greater depth, as well as to assess the ideal duration of therapy. Registration number: PROSPERO CRD42021288323. 1 condition Traditionally expectancy disease suicide treatment metaanalyses, metaanalyses meta analyses, analyses meta-analyses included 4860 4 860 4,86 5 selected indicated pregabalin antipsychotics quetiapine studied third wave possibilities Brazil medications depth number CRD42021288323 CRD 486 86 4,8 CRD4202128832 48 8 4, CRD420212883 CRD42021288 CRD4202128 CRD420212 CRD42021 CRD4202 CRD420 CRD42 CRD4
8.
Development of spectroscopic methods for assessing polymorphic content of efavirenz
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Rosa, Talita Atanazio
; Oliveira, Marcos Victor Gregório de
; França, Leandro de Moura
; Lima, Maria Joanellys dos Santos
; Silva, Pollyne Amorim
; Silva, Rosali Maria Ferreira da
; Rolim, Larissa Araújo
; Pimentel, Maria Fernanda
; Rolim Neto, Pedro José
.
Abstract The present work aimed to develop a new method for assessing the content of mixtures of polymorphic forms I and II of the drug Efavirenz (EFV) by vibrational spectroscopic techniques such as Middle (MIR) and Near (NIR) infrared and Raman, using multivariate calibration models. Benchtop and handheld instruments were used for NIR and Raman and a benchtop instrument for MIR. In addition, VIP scores and iPLS, variable selection methods were employed. The infrared techniques showed the best models, with Root Mean Squares Error (RMSE) around 5% (w/w). When MIR and portable NIR instruments were used, this value was lowered to 4% (w/w) with selection of variables by iPLS. Raman spectroscopy showed higher error, even with selection of variables, possibly due to the spot laser size used by instruments and the lack of uniformity of the particle size in the samples. The infrared methods developed were shown to be effective in quantifying polymorphic mixtures of EFV. Given the ease of use of handheld instruments, they may be applied as tools of process analytical technology for monitoring quality control during industrial processing. EFV (EFV (MIR (NIR models addition iPLS employed RMSE (RMSE 5 w/w. ww w/w . w 4 (w/w error samples processing
9.
Review of the dissolution tests in the Brazilian Pharmacopeia
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Guedes, Nathalia Maria
; Silva, José Geneilson
; Mesquita, Leandro Luiz Gomes de Miranda
; Castro, Whocely Victor de
; Lima, Ednalva de Sousa Pereira
; Santana, Davi Pereira de
; Bedor, Danilo Cesar Galindo
.
Abstract Dissolution tests evaluate the release of therapeutic agents in various dosage forms, acting as quality control tools to secure batch–batch equivalence and guides for formulation development and in vivo drug bioavailability prediction for pharmaceutical scientists. In this article, dissolution tests described in the Brazilian Pharmacopeia 6th ed. were systematically reviewed using the following descriptors: drug, dosage forms, apparatus, rotational speed, dissolution media, sampling time, quantitative procedure, and the value of Q . Test conditions were compared with those described in the United States Pharmacopeia (USP) dissolution database. In September, 2023, dissolution tests were required for 127 monographs, accounting for only 10% of those listed in the USP database. Paddles were used in 80 monographs (63.5%) at various rotation speeds. Basket apparatus was recommended for 47 products, including tablets, capsules, and gastro-resistant granules with variable speed ranges. The simulated gastric fluid was described in four monographs. Moreover, pH of the dissolution media for 29 products was adjusted in the physiological range of 2–7.5. Twenty-eight monographs are exclusively listed in the Brazilian Pharmacopeia. Among the 99 products listed in both compendiums, dissolution tests were only harmonized for 69 monographs. forms batchbatch batch scientists article th ed descriptors time procedure (USP database September 2023 12 10 8 63.5% 635 63 5 (63.5% speeds 4 tablets capsules gastroresistant gastro resistant ranges Moreover 2 275 7 2–7.5 Twentyeight Twenty eight 9 compendiums 6 202 1 63.5 (63.5 27 2–7. 20 63. (63. 2–7 (63 2– (6 (
10.
Social support and suicidality during the COVID-2019 pandemic among Brazilian health care workers: longitudinal assessment of a repeated cross-sectional online survey COVID2019 COVID 2019 COVID-201 workers crosssectional cross sectional COVID201 201 COVID-20 COVID20 20 COVID-2 COVID2 2 COVID-
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Diaz, Alexandre Paim
; Pinto, Andre Braule
; Araújo, Maria Isabel Chaves
; Joaquim, Rui Mateus
; Costa, Danielle de Souza
; Serpa, Alexandre Luiz de Oliveira
; Pisani, Anthony R.
; Conwell, Yeates
; Miranda, Debora M.
; Malloy-Diniz, Leandro F.
; da Silva, Antonio G.
.
Objective: The risk of suicide is higher among health care workers than other workers. This study investigated the association between social support and suicidal ideation and behavior during the COVID-19 pandemic among Brazilian health care workers. Methods: This study used data from 10,885 respondents to the first (time point 1 – between May and June of 2020) and second (time point 2 – between December 2020 and February 2021) cross-sectional online surveys about mental health and quality of life among Brazilian health care workers during the COVID-19 pandemic. The relationship between social support as the independent variable (time point 1) and suicidal ideation and behavior as the outcomes (time point 2) was investigated through logistic regression analysis. Results: Greater social support was associated with a significantly lower risk of reporting suicidal ideation and behavior in the month prior to follow-up assessment (adjusted OR: 0.71, 95%CI 0.66-0.76 and adjusted OR 0.61, 95%CI 0.54-0.68, respectively). These associations were independent of sex, age, feelings of loneliness, and self-reported psychiatric disorders. Conclusion: Social support is associated with a lower risk of suicidality among health care workers, and its protective role appears more closely related to suicidal behavior. Objective COVID19 COVID 19 COVID-1 Methods 10885 10 885 10,88 time 202 2021 crosssectional cross sectional analysis Results followup follow up 071 0 71 0.71 95CI CI 95 0.660.76 066076 0.66 0.76 66 76 0.66-0.7 061 61 0.61 0.540.68, 054068 0.54 0.68, 54 68 0.54-0.68 respectively. respectively . respectively) sex age loneliness selfreported self reported disorders Conclusion COVID1 COVID- 1088 88 10,8 20 07 7 0.7 9 660 0.660.7 06607 066 0.6 076 6 0.66-0. 06 540 0.540.68 05406 054 0.5 068 0.68 5 0.54-0.6 108 8 10, 0. 0.660. 0660 0.66-0 0.540.6 0540 05 0.54-0. 0.660 0.66- 0.540. 0.54-0 0.540 0.54-
11.
Translation and cross-cultural adaptation of the Yale Pharyngeal Residue Severity Rating Scale into Brazilian Portuguese crosscultural cross cultural
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Venite, Roberta Seabra
; Pernambuco, Leandro
; Silva, Roberta Gonçalves da
; Onofri, Suely Mayumi Motonaga
.
Abstract Objective To report the process of translation and cross-cultural adaptation of theYale Pharyngeal Residue Severity Rating Scale into Brazilian Portuguese. Methods Methodological study approved by the Ethics Committee of the Institution (nº 5.166.256). The English original scale was translated into Brazilian Portuguese following suggested in the literature guidelines and recommendations after authorization from the authors of the original instrument, and involved the following reported steps of (1) Translation, (2) Synthesis of translations, (3) Determination of the applicability of the translated version 4) Back-translation, (5) Synthesis of the back-translated versions, and (6) Final synthesis. The translations and back-translations were performed by two bilingual translators. The research committee constituted three specialists who considered whether the linguistic, semantics, conceptual, idiomatic, and contextual equivalence of the translations and back-translations were. In Step 3, the raters consisted of three Speech-Language Pathologists and five ENT physicians divided into two subgroups (less than 5 years of professional expertise, and more than 5 years of professional expertise). Results Step 1 was carried out properly by the translators, in Step 2 the translated version was prepared after minor adjustments. In Step 3, the raters reported that they found no difficulties in applying the scale. The Cronbach's Alpha coefficient was 0.995, demonstrating high internal consistency of the instrument, and the analysis of the Intraclass Correlation Coefficient (ICC) among the eight raters was 0.994 with a confidence interval between 0.990 and 0.998, demonstrating excellent agreement, regardless of experience. The research committee judged the last to be adequate and not to require adjustments. Conclusion The Brazilian Portuguese version of theYale Pharyngeal Residue Severity Rating Scale is presented in this study. This is a methodological study - No level of evidence. crosscultural cross cultural nº 5.166.256. 5166256 5.166.256 . 166 256 5.166.256) instrument (1 Translation (2 3 (3 4 Backtranslation, Backtranslation Back translation, Back-translation (5 backtranslated back versions 6 (6 synthesis backtranslations translators linguistic semantics conceptual idiomatic SpeechLanguage Speech Language less expertise expertise. expertise) adjustments Cronbachs Cronbach s 0995 0 995 0.995 ICC (ICC 0994 994 0.99 0990 990 0998 998 0.998 agreement experience evidence 516625 5.166.25 16 25 ( 099 99 0.9 51662 5.166.2 09 9 0. 5166 5.166. 516 5.166 51 5.16 5.1 5.
12.
Pure and Cobalt-Modified ZnO Nanostructures Prepared by a New Synthesis Route Applied to Environmental Remediation CobaltModified Cobalt Modified
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Nobrega, Eryka T. D.
; Araújo, Kelvin C. de
; Moreira, Ailton J.
; Oliveira, Regiane C. de
; Silva, Gelson T. S. T. da
; Blaskievicz, Sirlon F.
; Soares, Leandro L.
; Lemos, Sherlan G.
; Mascaro, Lucia H.
; Pereira, Ernesto C.
.
Journal of the Brazilian Chemical Society
- Journal Metrics
Pure and cobalt-doped 3D ZnO were produced using the microwave (MW)-ultraviolet (UV)-visible (Vis) radiation-assisted hydrothermal method (MW-UV-Vis HM). Using experimental design, the effects of cobalt and UV-Vis radiation during the synthesis stage on the physicochemical properties of the materials were evaluated with different characterization techniques such as X-ray diffraction, scanning and transmission electron microscopy, diffuse reflectance, and electrochemistry. The presence of cobalt had a great influence on the reduction of charge donors in the ZnO matrix and had their photocatalytic properties improved when produced under the effect of UV-Vis radiation. The catalytic activity of the materials has been verified in important environmental remediation reactions, such as the electrochemical reduction of CO2 and the photocatalytic degradation of emerging pollutants. The results achieved in this study show competitive efficiency values for CO2 reduction (97%) and photocatalytic degradation (91%) of emerging pollutants in natural waters, illustrating the great versatility of the produced material in distinct applications. cobaltdoped doped D MWultraviolet MW ultraviolet UVvisible UV visible Vis (Vis radiationassisted assisted MWUVVis HM. HM . HM) design UVVis Xray X ray diffraction microscopy reflectance electrochemistry reactions CO 97% 97 (97% 91% 91 (91% waters applications 9 (97 (91 (9 (
13.
SEQUENTIAL DETERMINATION OF Zn, Fe, Mg, Ca, Na AND K IN SYNTHETIZED BABASSU FAME BY HIGH RESOLUTION CONTINUUM SOURCE FLAME ATOMIC ABSORPTION SPECTROMETRY Zn Fe Mg Ca
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Boeira, Ana Carla S.
; Kolling, Leandro
; Santos, Samuel J.
; Fontoura, Luiz A. M.
; Silva, Márcia Messias da
.
In this work, babassu FAME samples were synthesized by transesterification reaction under alkaline catalysis with sodium glyceroxide and by two steps process with KOH followed by H2SO4 as catalysts. A sequential multi-element method for determination of Zn, Fe, Mg, Ca, Na and K in synthesized babassu FAME by high resolution continuum source flame atomic absorption spectrometry (HR CS FAAS) was developed. The proposed method is based on a microemulsion formation by mixing the babassu FAME samples with 1-propanol and aqueous phase. The mass proportion of the added components was evaluated through a ternary diagram. External and matrix-matching calibration techniques with inorganic and organic standard were investigated. In the five-level spike-recovery test, satisfactory results were obtained by performing the matrix-matching calibration along with inorganic standard solutions. By using the optimized conditions, limits of detection in the range of 0.002-0.12 mg kg-1 were obtained. Accuracy was attested by the agreement of the results obtained in the analysis of three certified reference materials. By applying the microemulsion system and HR-CS FAAS, the sequential determination of six elements was achieved. Therefore, the proposed method was a suitable alternative for metal determination in babassu FAME samples, with good sensitivities, accuracy, and a wide linear working range. work HSO H SO H2SO catalysts multielement multi element Zn Fe Mg Ca HR FAAS developed 1propanol propanol 1 phase diagram matrixmatching matrix matching investigated fivelevel five level spikerecovery spike recovery test solutions conditions 0.0020.12 0002012 0.002 0.12 0 002 12 0.002-0.1 kg1 kg kg- materials HRCS achieved Therefore sensitivities accuracy 0020 0.0020.1 000201 0002 0.00 012 0.1 00 0.002-0. 0.0020. 00020 000 0.0 01 0. 0.002-0 0.0020 0.002-
14.
Red Propolis: Chemical and Mid-Infrared Spectroscopic Characterization and Classification by Geographic Origin Propolis MidInfrared Mid Infrared
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Lima, Amanda B. S. de
; Oliveira, Thinara F.
; Silva, Marcondes V. da
; Ferrão, Sibelli P. B.
; Almeida, Vítor V. S. de
; Santos, Leandro S.
.
In this paper, we report the characterization of Brazilian red propolis from two origins. The commercial value of this product is due to its composition and bioactivity, which depend on geographical factors. Total and individual phenolic, antioxidant, and medium infrared spectroscopic (MIR) characterization of 72 red propolis samples from two origins (Bahia (BA) and Rio Grande do Norte (RN), Brazil) were performed. Samples from RN showed higher concentrations of biomarkers. The BA samples showed higher antioxidant capacity despite having lower concentrations of the red propolis biomarker molecules when compared to the RN samples. The MIRS showed differences regarding the origin. The principal component analysis confirmed the differences, generating well-defined groups. Linear discriminant analysis or discriminant analysis and and partial least squares discriminant analysis showed excellent model performance. The models with MIRS data from raw propolis have a high correct classification rate and require no sample preparation. These findings can affect red propolis production, boosting sustainable extractivism, and changing the reality of small communities. paper bioactivity factors phenolic MIR (MIR 7 Bahia (BA RN, , (RN) Brazil performed biomarkers origin welldefined well defined groups performance preparation production extractivism communities (RN
15.
Advances in diffuse glial tumors diagnosis
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Godoy, Luis Filipe de Souza
; Paes, Vitor Ribeiro
; Ayres, Aline Sgnolf
; Bandeira, Gabriela Alencar
; Moreno, Raquel Andrade
; Hirata, Fabiana de Campos Cordeiro
; Silva, Frederico Adolfo Benevides
; Nascimento, Felipe
; Campos Neto, Guilherme de Carvalho
; Gentil, Andre Felix
; Lucato, Leandro Tavares
; Amaro Junior, Edson
; Young, Robert J.
; Malheiros, Suzana Maria Fleury
.
Abstract In recent decades, there have been significant advances in the diagnosis of diffuse gliomas, driven by the integration of novel technologies. These advancements have deepened our understanding of tumor oncogenesis, enabling a more refined stratification of the biological behavior of these neoplasms. This progress culminated in the fifth edition of the WHO classification of central nervous system (CNS) tumors in 2021. This comprehensive review article aims to elucidate these advances within a multidisciplinary framework, contextualized within the backdrop of the new classification. This article will explore morphologic pathology and molecular/genetics techniques (immunohistochemistry, genetic sequencing, and methylation profiling), which are pivotal in diagnosis, besides the correlation of structural neuroimaging radiophenotypes to pathology and genetics. It briefly reviews the usefulness of tractography and functional neuroimaging in surgical planning. Additionally, the article addresses the value of other functional imaging techniques such as perfusion MRI, spectroscopy, and nuclear medicine in distinguishing tumor progression from treatment-related changes. Furthermore, it discusses the advantages of evolving diagnostic techniques in classifying these tumors, as well as their limitations in terms of availability and utilization. Moreover, the expanding domains of data processing, artificial intelligence, radiomics, and radiogenomics hold great promise and may soon exert a substantial influence on glioma diagnosis. These innovative technologies have the potential to revolutionize our approach to these tumors. Ultimately, this review underscores the fundamental importance of multidisciplinary collaboration in employing recent diagnostic advancements, thereby hoping to translate them into improved quality of life and extended survival for glioma patients. decades gliomas oncogenesis neoplasms CNS (CNS 2021 framework moleculargenetics molecular genetics immunohistochemistry, immunohistochemistry (immunohistochemistry sequencing profiling, profiling , profiling) planning Additionally MRI spectroscopy treatmentrelated treatment related changes Furthermore utilization Moreover processing intelligence radiomics Ultimately patients 202 20 2
Resumo Nas últimas décadas, houve avanços significativos no diagnóstico de gliomas difusos, impulsionados pela integração de novas tecnologias. Esses avanços aprofundaram nossa compreensão da oncogênese tumoral, permitindo uma estratificação mais refinada do comportamento biológico dessas neoplasias. Esse progresso culminou na quinta edição da classificação da OMS de tumores do sistema nervoso central (SNC) em 2021. Esta revisão abrangente tem como objetivo elucidar esses avanços de forma multidisciplinar, no contexto da nova classificação. Este artigo irá explorar a patologia morfológica e as técnicas moleculares/genéticas (imuno-histoquímica, sequenciamento genético e perfil de metilação), que são fundamentais no diagnóstico, além da correlação dos radiofenótipos da neuroimagem estrutural com a patologia e a genética. Aborda sucintamente a utilidade da tractografia e da neuroimagem funcional no planejamento cirúrgico. Destacaremos o valor de outras técnicas de imagem funcional, como ressonância magnética de perfusão, espectroscopia e medicina nuclear, na distinção entre a progressão do tumor e as alterações relacionadas ao tratamento. Discutiremos as vantagens das diferentes técnicas de diagnóstico na classificação desses tumores, bem como suas limitações em termos de disponibilidade e utilização. Além disso, os crescentes avanços no processamento de dados, inteligência artificial, radiômica e radiogenômica têm grande potencial e podem em breve exercer uma influência substancial no diagnóstico de gliomas. Essas tecnologias inovadoras têm o potencial de revolucionar nossa abordagem a esses tumores. Em última análise, esta revisão destaca a importância fundamental da colaboração multidisciplinar na utilização dos recentes avanços diagnósticos, com a esperança de traduzi-los em uma melhor qualidade de vida e uma maior sobrevida. décadas difusos tumoral neoplasias SNC (SNC 2021 molecularesgenéticas moleculares genéticas imunohistoquímica, imunohistoquímica imuno histoquímica, histoquímica (imuno-histoquímica metilação, metilação , metilação) genética cirúrgico perfusão nuclear tratamento disso dados artificial análise diagnósticos traduzilos traduzi los sobrevida 202 20 2
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