Resumen Objetivo Identificar la frecuencia de lesión renal aguda (LRA) en pacientes hospitalizados con COVID-19, las características relacionadas, la mortalidad y la letalidad. Métodos Revisión realizada en las bases de datos CINAHL, Embase, LILACS, Livivo, PubMed, SCOPUS, Web of Science y en la literatura gris (Google Académico) el 12 de enero de 2022. Se incluyeron artículos en inglés, español y portugués, publicados a partir de noviembre de 2019 hasta enero de 2022, con pacientes mayores de 18 años con COVID-19 hospitalizados y LRA de acuerdo con el criterio Kidney Disease Improving Global Outcomes (KDIGO). Los estudios seleccionados fueron leídos en su totalidad para extracción, interpretación, síntesis y categorización según el nivel de evidencia. Resultados Se encontraron 699 artículos y se incluyeron 45. Los factores relacionados con la LRA fueron: edad avanzada, sexo masculino, hipertensión, enfermedad renal crónica, ventilación mecánica, aumento de la proteína C reactiva, uso de drogas vasoactivas y de determinadas clases de antihipertensivos. La LRA está relacionada con mayor frecuencia de mortalidad. En el 30 % de los pacientes hospitalizados con COVID-19 hubo LRA. La tasa de mortalidad por LRA fue de 5 % y la letalidad de 18 %. Conclusión Estos resultados resaltan la relevancia de la LRA como una complicación significativa de COVID-19 y sugieren que un control más cuidadoso y temprano de los factores asociados podría reducir potencialmente la mortalidad y la letalidad. Es crucial intensificar la investigación en este campo para explicar mejor los mecanismos relacionados con la lesión renal en pacientes con COVID-19, así como identificar estrategias terapéuticas más efectivas para su prevención y tratamiento en este contexto. (LRA COVID19, COVID19 COVID 19, 19 relacionadas CINAHL Embase LILACS Livivo PubMed SCOPUS Google Académico 1 2022 inglés portugués 201 COVID-1 KDIGO. KDIGO . (KDIGO) extracción interpretación evidencia 69 45 avanzada masculino hipertensión crónica mecánica reactiva antihipertensivos 3 contexto COVID1 202 20 COVID- (KDIGO 6 4 2

Abstract Objective To identify the frequency of acute kidney injury (AKI) in patients hospitalized with COVID-19, associated characteristics, mortality and lethality. Methods Integrative review carried out in the databases CINAHL, Embase, LILACS, Livivo, PubMed, SCOPUS, Web of Science and in the grey literature (Google Scholar) on January 12, 2022. Articles were included in English, Spanish and Portuguese, published from November 2019 to January 2022, in hospitalized patients over 18 years old with COVID-19 and AKI according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria. The selected studies were read in full for extraction, interpretation, synthesis and categorization according to the level of evidence. Results A total of 699 articles were found and 45 included. Older age, male gender, hypertension, chronic kidney disease, mechanical ventilation, increased C-reactive protein, use of vasoactive drugs and certain classes of antihypertensives were associated with AKI. AKI is related to a higher frequency of mortality. AKI occurred in 30% of patients hospitalized with COVID-19. The mortality rate from AKI was 5% and the case fatality rate was 18%. Conclusion These results highlight the relevance of AKI as a significant complication of COVID-19 and suggest that more careful and early control of associated factors could potentially reduce mortality and lethality. It is crucial to intensify research in this field to better clarify the mechanisms involved in kidney injury in COVID-19 patients, as well as to identify more effective therapeutic strategies for its prevention and treatment in this context. (AKI COVID19, COVID19 COVID 19, 19 characteristics lethality CINAHL Embase LILACS Livivo PubMed SCOPUS Google Scholar 12 2022 English Portuguese 201 1 COVID-1 KDIGO (KDIGO criteria extraction interpretation evidence 69 4 age gender hypertension disease ventilation Creactive C reactive protein 30 COVID19. 19. 5 18% context COVID1 202 20 COVID- 6 3 2

Resumo Objetivo Identificar a frequência de lesão renal aguda (LRA) em pacientes hospitalizados com COVID-19, as características associadas, a mortalidade e a letalidade. Métodos Revisão realizada nas bases de dados CINAHL, Embase, LILACS, Livivo, PubMed, SCOPUS, Web of Science e, na literatura cinzenta (Google Acadêmico) em 12 de janeiro de 2022. Foram incluídos artigos em inglês, espanhol e português, publicados a partir de novembro 2019 até janeiro de 2022, em pacientes maiores de 18 anos com COVID-19 hospitalizados e LRA conforme critério Kidney Disease Improving Global Outcomes (KDIGO). Os estudos selecionados foram lidos na íntegra para extração, interpretação, síntese e categorização conforme nível de evidência. Resultados 699 artigos encontrados e 45 incluídos. A idade avançada, sexo masculino, hipertensão, doença renal crônica, ventilação mecânica, aumento da proteína C reativa, uso de drogas vasoativas e de determinadas classes de anti-hipertensivos foram associados a LRA. A LRA está relacionada à maior frequência de mortalidade. Em 30% dos pacientes hospitalizados com COVID-19 houve LRA. A taxa de mortalidade por LRA foi de 5% e a letalidade de 18%. Conclusão Estes resultados ressaltam a relevância da LRA como uma complicação significativa da COVID-19 e sugerem que um controle mais cuidadoso e precoce dos fatores associados poderia potencialmente reduzir a mortalidade e a letalidade. É crucial intensificar a pesquisa nesse campo para esclarecer melhor os mecanismos envolvidos na lesão renal em pacientes com COVID-19, bem como identificar estratégias terapêuticas mais efetivas para sua prevenção e tratamento nesse contexto. (LRA COVID19, COVID19 COVID 19, 19 associadas CINAHL Embase LILACS Livivo PubMed SCOPUS Google Acadêmico 1 2022 inglês português 201 COVID-1 KDIGO. KDIGO . (KDIGO) extração interpretação evidência 69 4 avançada masculino hipertensão crônica mecânica reativa antihipertensivos anti hipertensivos 30 5 18% contexto COVID1 202 20 COVID- (KDIGO 6 3 2

ABSTRACT Giant hepatic hemangiomas are occasional in patients with cirrhosis. It remains a challenge to decide on the need for treatment and choose the most appropriate intervention. A 62-year-old woman was recently diagnosed with cirrhosis and complained of upper abdominal fullness, reduction in oral food intake, and weight loss of 6 kg over the last three years. Upper digestive endoscopy evidenced thin-caliber esophageal varices and significant extrinsic compression of the lesser gastric curvature. Abdominal computed tomography revealed an exophytic tumor in the left hepatic lobe, measuring 11.5 cm, which had progressive centripetal contrast enhancement from the arterial phase, compatible with hepatic hemangioma. Serum tumor markers were negative, and her liver function was unimpaired. The patient underwent surgical resection (non-anatomical hepatectomy of segments II and III) which had no immediate complications, and the histopathological evaluation confirmed cavernous hepatic hemangioma. Two weeks later, she was admitted to the emergency room with jaundice, signs of hepatic encephalopathy, and moderate ascites, and was further diagnosed with secondary bacterial peritonitis. As no perforations, abscesses, or fistulas were observed on subsequent imaging tests, clinical management was successfully carried out. This case highlights that giant hepatic hemangiomas may be symptomatic and warrant treatment. In the setting of cirrhosis and portal hypertension, physicians should be aware of the risk of hepatic decompensation following surgical resection, even in patients with Child-Pugh class A. intervention 62yearold yearold 62 year old fullness intake years thincaliber thin caliber curvature lobe 115 11 5 11. cm phase hemangioma negative unimpaired nonanatomical non anatomical III complications later jaundice encephalopathy ascites peritonitis perforations abscesses tests out hypertension ChildPugh Child Pugh 1

Abstract This article explores the effects of social markers of gender, race and socioeconomic status (SES) on bullying among 9th-grade students in Brazil. The aim is to investigate whether students from privileged social groups within the social hierarchy (i.e., men, white individuals, and those of higher SES) exhibit higher rates of bullying perpetration, and conversely, whether students from disadvantaged social groups (women, black individuals, and those of lower SES) are more likely to be victims of these acts. We analyzed data from the 2015 National Survey of School Health (PeNSE) through Hierarchical Generalized Linear Models (HGLM) adjusted separately for public and private schools and for different types of student involvement with bullying: as victim, aggressor, or victim-aggressor. The results indicate that, only as to SES, we can state that bullying reproduces the status hierarchy found in society. In both public and private schools, students with a higher SES are more likely to bully someone, while students with a lower SES are more likely to be bullied. As for gender, it is observed that male students are more prone to be involved in bullying than female students, whether as a victim, aggressor, or victim-aggressor. Differentials are more significant in private schools than in public schools. As for race, it is observed that acting like a bully permeates racial groups in multiple ways. gender (SES 9thgrade thgrade 9th grade th Brazil i.e., ie i e (i.e. men individuals perpetration conversely women, women (women acts 201 PeNSE (PeNSE HGLM (HGLM victim aggressor victimaggressor. victimaggressor aggressor. victim-aggressor society someone bullied ways i.e. (i.e 20 i.e 2

Resumo O artigo investiga os efeitos dos marcadores sociais de gênero, raça e nível socioeconômico sobre o bullying entre os alunos do 9º ano do ensino fundamental no Brasil. O objetivo é verificar se o fenômeno está relacionado com hierarquias de poder estabelecidas na sociedade, de modo que alunos integrantes dos grupos sociais privilegiados na hierarquia social (isto é, homens, brancos e de nível socioeconômico mais elevado) tendem a praticar mais bullying e discentes de grupos sociais desfavorecidos (mulheres, negros e de nível socioeconômico mais baixo) tendem a sofrer mais bullying . Analisamos dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) 2015 a partir de Modelos Lineares Generalizados Hierárquicos (MLGH). As análises são feitas separadamente para escolas públicas e privadas e os diferentes tipos de envolvimento dos alunos com o bullying , seja como vítima, agressor e vítima-agressor. Os resultados apontam que, apenas no que se refere ao nível socioeconômico, podemos afirmar que o bullying reproduz a hierarquia de status presente na sociedade. Tanto na escola pública quanto na privada, os alunos de maior nível socioeconômico estão mais propensos a praticarem, enquanto os de menor nível estão mais propensos a sofrerem bullying . Quanto ao gênero, verifica-se que os alunos do sexo masculino têm maior propensão ao envolvimento com o bullying do que as meninas, seja como vítima, agressor ou vítima-agressor. Os diferenciais são mais expressivos nas escolas privadas que nas públicas. No que se refere à raça, observa-se que o envolvimento com o bullying permeia os grupos raciais em múltiplos sentidos. gênero º Brasil sociedade isto homens elevado mulheres, mulheres (mulheres baixo PeNSE (PeNSE 201 MLGH. MLGH (MLGH) vítima vítimaagressor. vítimaagressor agressor. vítima-agressor privada praticarem verificase verifica meninas observase observa sentidos 20 (MLGH 2

Abstract This research assessed the efficiency of chemically modified tannins as coagulants for water treatment. Tannins from Anacardium occidentale (cashew tree) and Mimosa caesalpiniifolia (‘sabiá’) barks and seedless fruits of Anadenanthera colubrina (‘angico’) and Pityrocarpa moniliformis (‘angico de bezerro’) were evaluated after cationization to remove turbidity from water. After extraction, the total solids content (TSC), Stiasny index (SI), and total condensed tannins content (TCC) of the tannins extracts were determined. Extracted tannins were converted into powders and cationized. Then, the cationized tannins' effectiveness on water turbidity removal, sedimentation time, and effect on pH were assessed. Three concentrations of each type of tannin were used to evaluate flocculant efficiency: 50, 100, and 150 mg L-1. Although the P. moniliformis extract had a higher TSC value (56.06%), it presented the lowest SI (0.42%) and TTC (0.23%) values. M. caesalpiniifolia had the lowest TSC (9.18%) and the highest SI (91.27%), while Ac occidentale stood out with the highest TCC (19.83%). All species have shown potential for tannin production and efficiently removed turbidity at all concentrations. However, only A. occidentale, at a concentration of 100 mg L-1, presented a nephelometric turbidity unit of 2.4, reaching the potability standards required by international specifications and, therefore, being indicated for water treatment. treatment cashew tree ‘sabiá sabiá (‘sabiá’ ‘angico angico (‘angico’ bezerro bezerro’ extraction TSC, , (TSC) SI, (SI) (TCC determined Then removal time 50 15 L1. L1 L 1. 1 L-1 P 56.06%, 5606 56.06% 56 06 (56.06%) 0.42% 042 0 42 (0.42% 0.23% 023 23 (0.23% values M 9.18% 918 9 18 (9.18% 91.27%, 9127 91.27% 91 27 (91.27%) 19.83%. 1983 19.83% . 19 83 (19.83%) However A 10 L1, 1, 24 2 4 2.4 therefore (‘sabiá (TSC (SI 5 L- 560 56.06 (56.06% 0.42 04 (0.42 0.23 02 (0.23 9.18 (9.18 912 91.27 (91.27% 198 19.83 8 (19.83% 2. 56.0 (56.06 0.4 (0.4 0.2 (0.2 9.1 (9.1 91.2 (91.27 19.8 (19.83 56. (56.0 0. (0. 9. (9. 91. (91.2 19. (19.8 (56. (0 (9 (91. (19. (56 ( (91 (19 (5 (1

Resumo O presente trabalho teve como objetivo avaliar a eficiência de taninos quimicamente modificados como coagulantes para tratamento de água. Os taninos das cascas de Anacardium occidentale (cajueiro) e Mimosa caesalpiniifolia (sabiá) e dos frutos sem sementes de Anadenanthera colubrina (angico) e Pityrocarpa moniliformis (angico de bezerro) foram avaliados após cationização para remover a turbidez da água. Após a extração, os extratos de taninos tiveram o teor de sólidos totais (TST), o índice de Stiasny (IS) e o teor de taninos totais condensados (TCT). Os taninos extraídos foram convertidos em pó e cationizados. Em seguida, avaliou-se a eficácia dos taninos cationizados na remoção da turbidez e o tempo de sedimentação além do efeito no pH da água. Para avaliar a eficiência dos taninos cationizados como floculantes foram utilizadas três concentrações de cada tipo de material: 50, 100 e 150 mg L-1. Embora o extrato de P. moniliformis tenha apresentado maior valor de TST (56,06%), apresentou os menores valores de IS (0,42%) e TCT (0,23%). Os taninos da casca de M. caesalpiniifolia apresentou o menor TST (9,18%) e o maior IS (91,27%), enquanto os derivados de A. occidentale se destacaram pelo maior TCT (19,83%). Todas as espécies demonstraram potencial para produção de taninos e foram eficientes em remover a turbidez da água em todas as concentrações. Porém, apenas o A. occidentale, na concentração de 100 mg L-1, apresentou unidade de turbidez nefelométrica de 2,4, atingindo os padrões de potabilidade exigidos pelas especificações internacionais e, portanto, sendo indicado para tratamento de água. cajueiro (cajueiro sabiá (sabiá angico bezerro extração TST, , (TST) (IS TCT. . (TCT) seguida avaliouse avaliou material 50 10 15 L1. L1 L 1. 1 L-1 P 56,06%, 5606 56,06% 56 06 (56,06%) 0,42% 042 0 42 (0,42% 0,23%. 023 0,23% 23 (0,23%) M 9,18% 918 9 18 (9,18% 91,27%, 9127 91,27% 91 27 (91,27%) A 19,83%. 1983 19,83% 19 83 (19,83%) Porém L1, 1, 24 2 4 2,4 portanto (TST (TCT 5 L- 560 56,06 (56,06% 0,42 04 (0,42 02 0,23 (0,23% 9,18 (9,18 912 91,27 (91,27% 198 19,83 8 (19,83% 2, 56,0 (56,06 0,4 (0,4 0,2 (0,23 9,1 (9,1 91,2 (91,27 19,8 (19,83 56, (56,0 0, (0, (0,2 9, (9, 91, (91,2 19, (19,8 (56, (0 (9 (91, (19, (56 ( (91 (19 (5 (1

Abstract The outdoor use of wood can be improved by coating the wood surface with varnish to reduce the effects of natural weathering. However, some varnishes quickly lose their ability to protect wood, and nanoscale additives have been used to mitigate this negative effect, preferably renewable and biodegradable. Therefore, the objective of this study was to evaluate the performance of varnishes reinforced with spray-dried nanofibrillated cellulose (NFC) in a natural weathering test. For this purpose, two varnishes, waterborne and non-waterborne, with 0, 5, and 10% (w/w) NFC addition were applied to Pinus taeda tangential wood samples, which were exposed to natural weathering for half a year, during the period from January to June 2019, in Curitiba, PR, Brazil. Adherence and impact resistance tests were performed to evaluate the surface properties of the varnishes, and the effect of natural weathering on the wood surface was evaluated using quantitative colorimetric analyses (CIELab System). The varnishes did not perform well in the adhesion and impact test. While no significant effects were observed in surface tests, due to the addition of spray-dried NFC, varnishes reinforced with 5% NFC exhibited reduced overall color variation, maintaining yellow and red pigmentation. This suggests that incorporating 5% spray-dried NFC into varnishes did not compromise coating properties and aided in mitigating the impact of natural weathering on wood color variation. However biodegradable Therefore spraydried spray dried (NFC test purpose nonwaterborne, nonwaterborne non waterborne, non-waterborne 0 5 10 w/w ww w (w/w samples year 2019 Curitiba PR Brazil CIELab System. System . System) variation pigmentation 1 201 20 2

ABSTRACT Wild birds have great prominence in the transmission of diseases to humans, mainly due to their ease of access to human populations, raising concerns about the potential impact of that proximity on public health. The present study reports ARV and PBV occurrence in wild birds from an environmental protection area in the Amazon biome, in Pará state, Brazil. We obtained 155 fecal specimens from 47 species of wild birds for RNA extraction, ARV and PBV detection utilizing molecular methods, nucleotide sequencing, and phylogenetic analysis. ARV prevalence was 0.6% (1/155), being positive in an individual of Myrmotherula longipennis, and PBV prevalence was 1.29% (2/155), affecting two individuals of Guira guira. The PBV strains were assigned to genogroup I based on phylogenetic analysis, and they shared a strong phylogenetic link with strains isolated from different geographic locations. The ARV strain was more closely related to strains that had previously circulated in the same region. The presence of ARV and PBV in this habitat suggests that infection cycles of these agents occur naturally in the wild ecosystem, potentially triggering transmission events between bird species and humans. This is the first study on ARV detection in wild birds in Brazil and the first report on the occurrence of PBV in wild Guira guira. Additional studies are required to determine the epidemiology, origin, evolution, and emergence of new potentially pathogenic viruses in the Amazon. humans populations health biome state 15 4 extraction methods sequencing analysis 06 0 6 0.6 1/155, 1155 1/155 , 1 (1/155) longipennis 129 29 1.29 2/155, 2155 2/155 2 (2/155) guira locations region ecosystem epidemiology origin evolution 0. 115 1/15 (1/155 12 1.2 215 2/15 (2/155 11 1/1 (1/15 1. 21 2/1 (2/15 1/ (1/1 2/ (2/1 (1/ (2/ (1 (2 (

RESUMO As aves silvestres têm grande destaque na transmissão de doenças ao homem, principalmente pela facilidade de acesso à população humana, levantando preocupações sobre o potencial impacto dessa proximidade no contexto da saúde pública. O presente estudo relata a ocorrência de ARV e PBV em aves silvestres de uma área de proteção ambiental no bioma Amazônico. Obtivemos 155 espécimes fecais de 47 espécies de aves silvestres, que foram submetidos a extração de RNA, detecção de ARV e PBV por técnicas moleculares, sequenciamento nucleotídico e análise filogenética. A prevalência de infecção por ARV foi 0,6% (1/155), sendo positivo em um indivíduo de Myrmotherula longipennis, e a prevalência de PBV foi 1,29% (2/155), afetando dois insdivíduos de Guira guira. A análise filogenética agrupou as cepas de PBV no genogrupo I, mostrando intensa relação filogenética com cepas isoladas de outras regiões geográficas. A cepa de ARV esteve mais relacionada filogeneticamente a cepas previamente circulantes na mesma região. Este é o primeiro estudo sobre detecção de ARV em aves silvestres no Brasil e o primeiro relato sobre a ocorrência de PBV em Guira guira. A circulação de ARV e PBV nesse ambiente demonstra que os ciclos desses agentes estão ocorrendo de forma natural no ecossistema silvestre, o que pode desencadear possíveis eventos de transmissão entre as espécies aviárias e humanos. Estudos adicionais são necessários para determinar a epidemiologia, origem, evolução e surgimento de novos vírus potencialmente patogênicos na Amazônia. homem humana pública Amazônico 15 4 RNA moleculares 06 0 6 0,6 1/155, 1155 1/155 , 1 (1/155) longipennis 129 29 1,29 2/155, 2155 2/155 2 (2/155) guira I geográficas região silvestre humanos epidemiologia origem Amazônia 0, 115 1/15 (1/155 12 1,2 215 2/15 (2/155 11 1/1 (1/15 1, 21 2/1 (2/15 1/ (1/1 2/ (2/1 (1/ (2/ (1 (2 (

Abstract Studies investigating the effects of different modalities of exercises on the immune system are scarce. Therefore, the aim of this study was to compare the effects of eight weeks of resistance and aerobic training on the proliferation of T and B lymphocytes from mice. Eighteen male C56BL6/J mice were divided into groups (n=6), sedentary, aerobic, and resistance training. After 8 weeks, animals were euthanized, and their splenocytes were labeled and cultured with and without stimulation. Lymphocyte proliferation (CD4+, CD8+ and CD21/CD35+) was evaluated by flow cytometry. The mice subjected to resistance exercise exhibited greater proliferation for total, CD8+ and B lymphocytes (p<0.05), but not CD4+ cells (p>0.05), compared with their sedentary counterparts. We found significant correlations between maximum load and total, CD8+ and B lymphocytes proliferation rates (p<0.05). In conclusion, our results showed that resistance training promoted an improvement in the immune response associated with CD8+ and B lymphocytes. scarce Therefore C56BL6J CBLJ C56BL6 J C BL n=6, n6 n n=6 , 6 (n=6) euthanized stimulation CD4+, CD4 CD (CD4+ CD8 CD21/CD35+ CD21CD35 CDCD CD21 CD35 cytometry total p<0.05, p005 p p<0.05 0 05 (p<0.05) p>0.05, p>0.05 (p>0.05) counterparts p<0.05. . conclusion CBL C56BL n= (n=6 (CD4 CD21/CD35 CD21CD3 CD2 CD3 p00 p<0.0 (p<0.05 p>0.0 (p>0.05 (n= (CD CD21/CD3 CD21CD p0 p<0. (p<0.0 p>0. (p>0.0 (n CD21/CD p<0 (p<0. p>0 (p>0. p< (p<0 p> (p>0 (p< (p> (p

Resumo Introdução: As doenças respiratórias agudas apresentam difícil mensuração e contribuem para o grande número de causas de óbito mal definidas, o que afeta a confiabilidade das informações de mortalidade. Objetivo: Verificar a acurácia da definição da causa básica de óbito para doenças respiratórias agudas dos óbitos registrados no Sistema de Informações sobre Mortalidade do Distrito Federal em 2018. Método: Foi realizado um estudo de acurácia, com amostra mínima de 331 declarações de óbito com as causas de óbito do capítulo 10 (doenças do aparelho respiratório — J00-J99 — conforme subcategorias) da Classificação Internacional de Doenças na versão 10, considerando a definição de causa básica de óbito pela equipe de investigação como o padrão-ouro. Foram calculadas a sensibilidade, especificidade, valores preditivos positivo e negativo e as razões de verossimilhanças positivas e negativas com os respectivos intervalos de confiança a 95%. Resultados: Total de 396 declarações de óbito foram incluídas. Foi constatada alta sensibilidade para identificar doenças pulmonares agudas nas causas básicas de óbito (82,8%. IC95% 78,6–86,5) e alta especificidade (93,1%. IC95% 77,2–99,2). A probabilidade de a declaração apresentar resultado falso negativo foi baixa (0,2. IC95% 0,1–0,2). Conclusão: As declarações de óbito por doenças respiratórias agudas apresentaram bons resultados para acurácia e incitam a realização de estudos semelhantes para outras condições. Introdução definidas mortalidade Objetivo 2018 Método 33 1 J00J99 JJ J00 J99 J J00-J9 subcategorias padrãoouro. padrãoouro padrão ouro. ouro padrão-ouro 95 95% Resultados 39 incluídas 82,8%. 828 82 8 (82,8% IC95 IC 78,6–86,5 786865 78 6 86 5 93,1%. 931 93 (93,1% 77,2–99,2. 772992 77,2–99,2 . 77 2 99 77,2–99,2) 0,2. 02 0 (0,2 0,1–0,2. 0102 0,1–0,2 0,1–0,2) Conclusão condições 201 3 J00J9 J0 J9 J00-J 9 82,8% (82,8 IC9 78,6–86, 78686 7 93,1% (93,1 77299 77,2–99, 0,2 (0, 010 0,1–0, 20 J00J 82,8 (82, 78,6–86 7868 93,1 (93, 7729 77,2–99 0, (0 01 0,1–0 82, (82 78,6–8 786 93, (93 772 77,2–9 ( 0,1– (8 78,6– (9 77,2– 0,1 78,6 77,2 78, 77,

Abstract Background: Acute respiratory diseases are difficult to measure and contribute to a large number of ill-defined causes of death, which affects the reliability of mortality information. Objective: To verify the accuracy of the definition of the underlying cause of death for acute respiratory diseases registered in the Mortality Information System of the Federal District in 2018. Method: An accuracy study was conducted, with a minimum sample of 331 death certificates with the causes of death according to Chapter 10 (diseases of the respiratory system — J00-J99 — according to subcategories) of the International Classification of Diseases, version 10, considering the definition of the underlying cause of death by the research team as the gold standard. Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios were calculated with their respective 95% confidence intervals (CIs). Results: Overall, 396 death certificates were included. High sensitivity was identified to determine acute lung diseases in the underlying cause of death (82.8%, 95%CI 78.6–86.5) and high specificity (93.1%, 95%CI 77.2–99.2). The probability of the declaration shows that negative false value was low (0.2, 95%CI 0.1–0.2). Conclusion: Death certificates due to acute respiratory diseases showed good results for accuracy and this study encourages similar studies for other conditions. Background illdefined ill defined information Objective 2018 Method conducted 33 1 J00J99 JJ J00 J99 J J00-J9 subcategories Diseases standard Sensitivity values 95 CIs. CIs . (CIs) Results Overall 39 included 82.8%, 828 82 8 (82.8% 95CI CI 78.6–86.5 786865 78 6 86 5 93.1%, 931 93 (93.1% 77.2–99.2. 772992 77.2–99.2 77 2 99 77.2–99.2) 0.2, 02 0 (0.2 0.1–0.2. 0102 0.1–0.2 0.1–0.2) Conclusion conditions 201 3 J00J9 J0 J9 J00-J 9 (CIs 82.8% (82.8 78.6–86. 78686 7 93.1% (93.1 77299 77.2–99. 0.2 (0. 010 0.1–0. 20 J00J 82.8 (82. 78.6–86 7868 93.1 (93. 7729 77.2–99 0. (0 01 0.1–0 82. (82 78.6–8 786 93. (93 772 77.2–9 ( 0.1– (8 78.6– (9 77.2– 0.1 78.6 77.2 78. 77.

RESUMO Objetivo: Estimar as prevalências e fatores associados com as hepatites A, B e C em mulheres trans e travestis em cinco regiões do Brasil. Métodos: Estudo transversal com mulheres trans e travestis em cinco capitais brasileiras (Campo Grande, Manaus, Porto Alegre, Salvador e São Paulo), entre dezembro/2019 e julho/2021. As amostras foram submetidas à detecção de marcadores das infecções pelos vírus das hepatites A (HAV), B (HBV) e C (HCV), utilizando-se testes rápidos e quimioluminescência. Amostras positivas foram submetidas à detecção de HBV-DNA e HCV-RNA por PCR em tempo real e genotipadas por sequenciamento de Sanger. Resultados: As análises de 1.317 amostras indicaram taxas de prevalências nas mulheres trans e travestis recrutadas de 69,1%, 24,4% e 1,5% para exposição ao HAV, HBV e HCV, respectivamente. Elevada taxa de suscetibilidade ao HBV (35,7%) e baixa prevalência do marcador vacinal (40,0%) foram observadas. Mostraram-se associadas à presença de anti-HAV: idade maior que 26 anos, autodeclarar-se preta-parda, ter apenas educação básica, história de encarceramento e uso de preservativo na última relação sexual com parceiro casual. Quanto à exposição ao HBV, foi associada a idade maior que 26 anos, cor da pele preto-parda, ter sido profissional do sexo e história de encarceramento. Idade maior de 37 anos, história de abuso sexual e consumo frequente de álcool foram associadas ao HCV. Conclusão: As maiores prevalências de HAV nessa população encontram-se nas regiões Norte e Nordeste. Com relação ao HBV, a prevalência encontrada foi superior à encontrada na população geral, sugerindo maior vulnerabilidade. A prevalência do HCV foi semelhante à encontrada na população geral. Objetivo Brasil Métodos Campo Grande Manaus Alegre Paulo, Paulo , Paulo) dezembro2019 dezembro 2019 dezembro/201 julho2021 julho 2021 julho/2021 (HAV) (HBV (HCV) utilizandose utilizando se quimioluminescência HBVDNA DNA HCVRNA RNA Sanger Resultados 1317 1 317 1.31 691 69 69,1% 244 24 4 24,4 15 5 1,5 respectivamente 35,7% 357 35 7 (35,7% 40,0% 400 40 0 (40,0% observadas Mostraramse Mostraram antiHAV anti anti-HAV 2 anos autodeclararse autodeclarar pretaparda, pretaparda preta parda, parda preta-parda básica casual pretoparda, pretoparda preto preto-parda 3 Conclusão encontramse encontram Nordeste geral vulnerabilidade dezembro201 201 dezembro/20 julho202 202 julho/202 (HAV (HCV 131 31 1.3 6 69,1 24, 1, 35,7 (35,7 40,0 (40,0 dezembro20 20 dezembro/2 julho20 julho/20 13 1. 69, 35, (35, 40, (40, dezembro2 dezembro/ julho2 julho/2 (35 (40 julho/ (3 (4 (

ABSTRACT Objective: To estimate the prevalence and factors associated with hepatitis A, B, and C in transgender women and travestis's networks, in 5 regions of Brazil. Methods: This cross-sectional study includedtransgender women and travestis in five Brazilian capitals (Campo Grande, Manaus, Porto Alegre, Salvador, and São Paulo), between December/2019 and July/2021. All samples were subjected to detection of serological markers of hepatitis virus A (HAV), B (HBV), and C (HCV) infections through rapid tests and chemiluminescent microparticle immunoassays. Positive samples in the screening tests were submitted to detect HBV DNA and HCV-RNA by real-time PCR and genotyped by Sanger sequencing. Results: Analysis of 1,317 samples showed network prevalence rates of 69.1%, 25.1%, and 1.5% for HAV, HBV, and HCV exposure, respectively. A high susceptibility rate to HBV infection (35.7%) and low prevalence of vaccine response markers (40%) were also observed. Age greater than 26 years, self-declared black/brown skin color, having only primary education, history of incarceration, and use of a condom in the last sexual intercourse with a casual partner were associated with total anti-HAV. Exposure to HBV was associated with age greater than 26 years, self-declared black/brown, history of being a sex worker, and incarceration. Age > 37 years, history of sexual abuse, and frequent alcohol consumption were associated with hepatitis C infection. Conclusion: The highest prevalence of HAV in this population was found in the North and Northeast regions, and the prevalence found was higher than that in the general population, suggesting greater vulnerability. The prevalence of HCV infection in our study was similar to that observed in the general population. Objective travestiss s networks Brazil Methods crosssectional cross sectional Campo Grande Manaus Alegre Salvador Paulo, Paulo , Paulo) December2019 December 2019 December/201 July2021 July 2021 July/2021 (HAV) (HBV) (HCV immunoassays HCVRNA RNA realtime real time sequencing Results 1317 1 317 1,31 691 69 69.1% 251 25 25.1% 15 1.5 exposure respectively 35.7% 357 35 7 (35.7% 40% 40 (40% 2 years selfdeclared self declared blackbrown black brown color education incarceration antiHAV. antiHAV anti HAV. anti-HAV worker 3 abuse Conclusion vulnerability December201 201 December/20 July202 202 July/202 (HAV (HBV 131 31 1,3 6 69.1 25.1 1. 35.7 (35.7 4 (40 December20 20 December/2 July20 July/20 13 1, 69. 25. 35. (35. (4 December2 December/ July2 July/2 (35 ( July/ (3

RESUMO Objetivo: Analisar as alterações físicas e psicológicas da infodemia de COVID-19 para a população idosa do Rio de Janeiro. Método: estudo transversal, web-based survey. para conhecimento do acesso a notícias e informações sobre COVID-19 de idosos do Rio de Janeiro, durante o período de julho a dezembro de 2020. Realizou-se análise univariada e análise bivariada com aplicação de métodos estatísticos não paramétricos. Resultados: Participaram 390 idosos, predominantemente do sexo feminino (75,1%), faixa etária entre 66 e 75 anos (35,4%), casados (51,0%), raça/cor branca (60,3%), com imóvel próprio (81,8%), localizado na zona urbana (91%), ensino básico completo ou incompleto (31,8%) e aposentados ou pensionistas (79,2%). Idosos mais jovens foram significativamente afetados tanto física quanto psicologicamente pelas redes sociais quando comparado a televisão (<0,001). Conclusão: Alterações físicas e psicológicas da exposição às informações sobre a COVID-19 têm afetado a vida dos idosos, gerando impacto para esta população. Objetivo COVID19 COVID 19 COVID-1 Janeiro Método transversal webbased web based survey 2020 Realizouse Realizou se paramétricos Resultados 39 75,1%, 751 75,1% , 1 (75,1%) 6 7 35,4%, 354 35,4% 35 4 (35,4%) 51,0%, 510 51,0% 51 0 (51,0%) raçacor raça cor 60,3%, 603 60,3% 60 3 (60,3%) 81,8%, 818 81,8% 81 8 (81,8%) 91%, 91 91% (91%) 31,8% 318 31 (31,8% 79,2%. 792 79,2% . 79 2 (79,2%) <0,001. 0001 <0,001 001 (<0,001) Conclusão COVID1 COVID- 202 75,1 (75,1% 35,4 (35,4% 51,0 5 (51,0% 60,3 (60,3% 81,8 (81,8% 9 (91% 31,8 (31,8 79,2 (79,2% 000 <0,00 00 (<0,001 20 75, (75,1 35, (35,4 51, (51,0 60, (60,3 81, (81,8 (91 31, (31, 79, (79,2 <0,0 (<0,00 (75, (35, (51, (60, (81, (9 (31 (79, <0, (<0,0 (75 (35 (51 (60 (81 ( (3 (79 <0 (<0, (7 (5 (6 (8 < (<0 (<

ABSTRACT Objective: to analyze the physical and psychological changes of the COVID-19 infodemic for the older adult population of Rio de Janeiro. Method: a cross-sectional, web-based survey to find out about access to news and information about COVID-19 among older adult in Rio de Janeiro, between July and December 2020. Univariate analysis and bivariate analysis were carried out using non-parametric statistical methods. Results: 390 older adults took part, predominantly female (75.1%), aged between 66 and 75 (35.4%), married (51.0%), white (60.3%), owning their own home (81.8%), located in urban areas (91%), with complete or incomplete primary education (31.8%) and retired or pensioners (79.2%). Younger people were significantly affected both physically and psychologically by social networks when compared to television (<0.001). Conclusion: Physical and psychological changes from exposure to information about COVID-19 have affected the lives of the older adult, having an impact on this population. Objective COVID19 COVID 19 COVID-1 Janeiro Method crosssectional, crosssectional cross sectional, sectional cross-sectional webbased web based 2020 nonparametric non parametric methods Results 39 part 75.1%, 751 75.1% , 1 (75.1%) 6 7 35.4%, 354 35.4% 35 4 (35.4%) 51.0%, 510 51.0% 51 0 (51.0%) 60.3%, 603 60.3% 60 3 (60.3%) 81.8%, 818 81.8% 81 8 (81.8%) 91%, 91 91% (91%) 31.8% 318 31 (31.8% 79.2%. 792 79.2% . 79 2 (79.2%) <0.001. 0001 <0.001 001 (<0.001) Conclusion COVID1 COVID- 202 75.1 (75.1% 35.4 (35.4% 51.0 5 (51.0% 60.3 (60.3% 81.8 (81.8% 9 (91% 31.8 (31.8 79.2 (79.2% 000 <0.00 00 (<0.001 20 75. (75.1 35. (35.4 51. (51.0 60. (60.3 81. (81.8 (91 31. (31. 79. (79.2 <0.0 (<0.00 (75. (35. (51. (60. (81. (9 (31 (79. <0. (<0.0 (75 (35 (51 (60 (81 ( (3 (79 <0 (<0. (7 (5 (6 (8 < (<0 (<

RESUMEN Objetivo: Analizar las alteraciones físicas y psicológicas de la infodemia de COVID-19 en adultos mayores de Río de Janeiro. Método: Se trata de un estudio transversal, basado en la web, llevado a cabo para conocer el acceso a noticias e información sobre el COVID-19 entre adultos mayores de Río de Janeiro, realizado entre julio y diciembre de 2020. Se ejecutaron análisis univariados y bivariados utilizando métodos estadísticos no paramétricos Resultados: Participaron 390 adultos mayores, predominantemente mujeres (75,1%), con edades comprendidas entre los 66 y los 75 años (35,4%), casadas (51,0%), blancas (60,3%), vivienda propia (81,8%), situada en zona urbana (91%), estudios primarios completos o incompletos (31,8%) y jubiladas o pensionistas (79,2%). Los adultos más jóvenes fueron bastante afectados, tanto física como psicológicamente, por las redes sociales en comparación con la televisión (<0,001). Conclusiones: Los cambios físicos y psicológicos derivados de la exposición a la información sobre COVID-19 han afectado la vida de los adultos mayores de manera impactante. Objetivo COVID19 COVID 19 COVID-1 Janeiro Método transversal web 2020 Resultados 39 75,1%, 751 75,1% , 1 (75,1%) 6 7 35,4%, 354 35,4% 35 4 (35,4%) 51,0%, 510 51,0% 51 0 (51,0%) 60,3%, 603 60,3% 60 3 (60,3%) 81,8%, 818 81,8% 81 8 (81,8%) 91%, 91 91% (91%) 31,8% 318 31 (31,8% 79,2%. 792 79,2% . 79 2 (79,2%) afectados psicológicamente <0,001. 0001 <0,001 001 (<0,001) Conclusiones impactante COVID1 COVID- 202 75,1 (75,1% 35,4 (35,4% 51,0 5 (51,0% 60,3 (60,3% 81,8 (81,8% 9 (91% 31,8 (31,8 79,2 (79,2% 000 <0,00 00 (<0,001 20 75, (75,1 35, (35,4 51, (51,0 60, (60,3 81, (81,8 (91 31, (31, 79, (79,2 <0,0 (<0,00 (75, (35, (51, (60, (81, (9 (31 (79, <0, (<0,0 (75 (35 (51 (60 (81 ( (3 (79 <0 (<0, (7 (5 (6 (8 < (<0 (<

ABSTRACT Objective: To estimate the prevalence and factors associated with hepatitis A, B, and C in transgender women and travestis's networks, in 5 regions of Brazil. Methods: This cross-sectional study includedtransgender women and travestis in five Brazilian capitals (Campo Grande, Manaus, Porto Alegre, Salvador, and São Paulo), between December/2019 and July/2021. All samples were subjected to detection of serological markers of hepatitis virus A (HAV), B (HBV), and C (HCV) infections through rapid tests and chemiluminescent microparticle immunoassays. Positive samples in the screening tests were submitted to detect HBV DNA and HCV-RNA by real-time PCR and genotyped by Sanger sequencing. Results: Analysis of 1,317 samples showed network prevalence rates of 69.1%, 25.1%, and 1.5% for HAV, HBV, and HCV exposure, respectively. A high susceptibility rate to HBV infection (35.7%) and low prevalence of vaccine response markers (40%) were also observed. Age greater than 26 years, self-declared black/brown skin color, having only primary education, history of incarceration, and use of a condom in the last sexual intercourse with a casual partner were associated with total anti-HAV. Exposure to HBV was associated with age greater than 26 years, self-declared black/brown, history of being a sex worker, and incarceration. Age > 37 years, history of sexual abuse, and frequent alcohol consumption were associated with hepatitis C infection. Conclusion: The highest prevalence of HAV in this population was found in the North and Northeast regions, and the prevalence found was higher than that in the general population, suggesting greater vulnerability. The prevalence of HCV infection in our study was similar to that observed in the general population.

RESUMO Objetivo: Estimar as prevalências e fatores associados com as hepatites A, B e C em mulheres trans e travestis em cinco regiões do Brasil. Métodos: Estudo transversal com mulheres trans e travestis em cinco capitais brasileiras (Campo Grande, Manaus, Porto Alegre, Salvador e São Paulo), entre dezembro/2019 e julho/2021. As amostras foram submetidas à detecção de marcadores das infecções pelos vírus das hepatites A (HAV), B (HBV) e C (HCV), utilizando-se testes rápidos e quimioluminescência. Amostras positivas foram submetidas à detecção de HBV-DNA e HCV-RNA por PCR em tempo real e genotipadas por sequenciamento de Sanger. Resultados: As análises de 1.317 amostras indicaram taxas de prevalências nas mulheres trans e travestis recrutadas de 69,1%, 24,4% e 1,5% para exposição ao HAV, HBV e HCV, respectivamente. Elevada taxa de suscetibilidade ao HBV (35,7%) e baixa prevalência do marcador vacinal (40,0%) foram observadas. Mostraram-se associadas à presença de anti-HAV: idade maior que 26 anos, autodeclarar-se preta-parda, ter apenas educação básica, história de encarceramento e uso de preservativo na última relação sexual com parceiro casual. Quanto à exposição ao HBV, foi associada a idade maior que 26 anos, cor da pele preto-parda, ter sido profissional do sexo e história de encarceramento. Idade maior de 37 anos, história de abuso sexual e consumo frequente de álcool foram associadas ao HCV. Conclusão: As maiores prevalências de HAV nessa população encontram-se nas regiões Norte e Nordeste. Com relação ao HBV, a prevalência encontrada foi superior à encontrada na população geral, sugerindo maior vulnerabilidade. A prevalência do HCV foi semelhante à encontrada na população geral.

Abstract: A hackathon is a short-term, collaborative and intensive event involving programming, design and the development of creative solutions to specific problems or challenges. The aim of this study is to analyze the concept of the innovation event - hackathon -, with a case study of the Hackatour Cataratas event. The methodology is exploratory and descriptive, with a qualitative approach and a case study. Hackathons are interesting for the tourism sector because they offer the opportunity to develop solutions with the participation of professionals from different areas. Looking specifically at Hackatour Cataratas, it was possible to identify positive impacts such as the development of innovative and technological solutions, in stimulating entrepreneurship, the event encouraged the creation of new companies and startups in the tourism sector, through the development of ideas and projects that can be transformed into businesses, in attracting investments, by presenting innovative solutions, the participating teams can attract the attention of investors interested in supporting projects in the tourism sector. The event has been taking place since 2015 in Foz do Iguaçu and/or online and has already had 12 editions with specific themes each year. Finally, they can contribute to improving the tourist experience, making travel more enjoyable, safe and efficient. The article mainly contributes to advancing the discussion on event innovation and its impact on the tourism market. Abstract shortterm, shortterm short term, term short-term programming challenges , descriptive areas entrepreneurship businesses investments 201 andor 1 year Finally experience enjoyable efficient market 20 2

Resumen: Un hackathon es un evento de corta duración, colaborativo e intensivo, que involucra programación, diseño y desarrollo de soluciones creativas para problemas o desafíos específicos. El objetivo de este estudio es analizar el concepto de evento de innovación - hackathon -, con un estudio de caso del evento Hackatour Cataratas. La metodología es exploratoria y descriptiva, con enfoque cualitativo y estudio de caso. Los hackathones son interesantes para el sector turístico porque ofrecen la oportunidad de desarrollar soluciones con la participación de profesionales de diferentes áreas. Mirando específicamente el Hackatour Cataratas, fue posible identificar impactos positivos como el desarrollo de soluciones innovadoras y tecnológicas, en el estímulo al emprendimiento, el evento incentivó la creación de nuevas empresas y startups en el sector turístico, a través del desarrollo de ideas y proyectos que pueden convertirse en negocios, en la atracción de inversiones, al presentar soluciones innovadoras, los equipos participantes pueden atraer la atención de inversores interesados en apoyar proyectos en el sector turístico. El evento se realiza desde 2015 en Foz do Iguaçu y / o en línea y ha tenido 12 ediciones con temas específicos cada año. Por último, pueden contribuir a mejorar la experiencia turística, haciendo que los viajes sean más agradables, seguros y eficientes. El artículo contribuye principalmente a avanzar en el debate sobre la innovación de eventos y su impacto en el mercado turístico. Resumen duración intensivo programación , Cataratas descriptiva áreas tecnológicas emprendimiento negocios inversiones 201 1 año último turística agradables eficientes 20 2

Resumo: O hackathon é um evento de curta duração, colaborativo e intensivo de programação, design e desenvolvimento de soluções criativas para problemas específicos ou desafios propostos. O objetivo deste estudo é analisar o conceito do evento de inovação - hackathon -, com estudo de caso do evento Hackatour Cataratas. A metodologia é exploratória e descritiva, de abordagem qualitativa, com estudo de caso. Os hackathons são interessantes para o setor de turismo, porque oferecem a oportunidade de desenvolver soluções com a participação de profissionais de diferentes áreas. Considerando especificamente o Hackatour Cataratas, foi possível identificar impactos positivos, como o desenvolvimento de soluções inovadoras e tecnológicas, no estímulo ao empreendedorismo. O evento incentivou a criação de novas empresas e startups no setor de turismo, por meio do desenvolvimento de ideias e projetos que possam ser transformados em negócios, na atração de investimentos, ao apresentarem soluções inovadoras, as equipes participantes podem chamar a atenção de investidores interessados em apoiar projetos no setor de turismo. O evento ocorre desde 2015, em Foz do Iguaçu e/ou online e já teve 12 edições, com temáticas específicas a cada ano. Por fim, podem contribuir para a melhoria da experiência do turista, tornando a viagem mais agradável, segura e eficiente. O artigo contribui, principalmente, com o avanço na discussão sobre a inovação dos eventos e seu impacto no mercado do turismo. Resumo duração programação propostos , Cataratas descritiva qualitativa turismo áreas positivos tecnológicas empreendedorismo negócios investimentos 2015 eou 1 edições ano fim turista agradável eficiente contribui principalmente 201 20 2

Objetivo: investigar la prevalencia de lesiones cutáneas y factores asociados con el uso de respiradores N95 en profesionales de la salud de Brasil. Método: estudio transversal realizado con 11.368 profesionales de la salud en el que se empleó un método de muestreo dirigido por encuestados adaptado para entornos en línea. Se ejecutaron análisis univariados y multivariados para investigar la asociación entre la variable “lesiones cutáneas por utilizar respiradores N95” y sexo, categoría profesional, lugar de trabajo, capacitación, diagnóstico de COVID-19 y disponibilidad de suficiente provisión de Equipo de Protección Personal de buena calidad. Resultados: la prevalencia de lesiones cutáneas fue del 61,8%. Las mujeres fueron 1,203 veces (IC 95%: 1,154-1,255) más propensas a desarrollar lesiones que los hombres. La probabilidad de lesiones cutáneas en psicólogos (RP=0,805; IC 95%: 0,678-0,956) y dentistas (RP=0,884; IC 95%: 0,788-0,992) fue menor en comparación con la encontrada en los profesionales de Enfermería. Los profesionales con diagnóstico positivo de COVID-19 y que trabajan en la Unidad de Cuidados Intensivos son más propensos a sufrir lesiones cutáneas (RP=1,074; IC 95%: 1,042-1,107); (RP=1,203; IC 95%: 1,168-1,241), respectivamente, Conclusión: la prevalencia de lesiones cutáneas causadas por utilizar respiradores N95 fue del 61,8% y estuvo asociada al sexo femenino, a la categoría profesional, al lugar de trabajo, a la capacitación, a diagnóstico de COVID-19 y a la disponibilidad de suficiente provisión de Equipo de Protección Personal de buena calidad. Objetivo N N9 Brasil Método 11368 11 368 11.36 línea profesional trabajo capacitación COVID19 COVID 19 COVID-1 calidad Resultados 618 61 8 1203 1 203 1,20 95% 95 1,1541,255 11541255 1,154 1,255 154 255 1,154-1,255 hombres RP=0,805 RP0805 RP 0 805 (RP=0,805 0,6780,956 06780956 0,678 0,956 678 956 0,678-0,956 RP=0,884 RP0884 884 (RP=0,884 0,7880,992 07880992 0,788 0,992 788 992 0,788-0,992 Enfermería RP=1,074 RP1074 074 (RP=1,074 1,0421,107 10421107 1,042 1,107 042 107 1,042-1,107) RP=1,203 RP1203 (RP=1,203 1,1681,241, 11681241 1,168 1,241 , 168 241 1,168-1,241) respectivamente Conclusión 61,8 femenino 1136 36 11.3 COVID1 COVID- 6 120 20 1,2 9 1541 1,1541,25 1154125 1154 1,15 1255 1,25 15 25 1,154-1,25 RP=0,80 RP080 80 (RP=0,80 6780 0,6780,95 0678095 0678 0,67 0956 0,95 67 0,678-0,95 RP=0,88 RP088 88 (RP=0,88 7880 0,7880,99 0788099 0788 0,78 0992 0,99 78 99 0,788-0,99 RP=1,07 RP107 07 (RP=1,07 0421 1,0421,10 1042110 1042 1,04 1107 1,10 04 10 1,042-1,107 RP=1,20 RP120 (RP=1,20 1681 1,1681,241 1168124 1168 1,16 1241 1,24 16 24 1,168-1,241 61, 113 3 11. 12 2 1, 1,1541,2 115412 115 1,1 125 1,154-1,2 RP=0,8 RP08 (RP=0,8 0,6780,9 067809 067 0,6 095 0,9 0,678-0,9 0,7880,9 078809 078 0,7 099 7 0,788-0,9 RP=1,0 RP10 (RP=1,0 1,0421,1 104211 104 1,0 110 1,042-1,10 RP=1,2 RP12 (RP=1,2 1,1681,24 116812 116 124 1,168-1,24 1,1541, 11541 1,154-1, RP=0, RP0 (RP=0, 0,6780, 06780 06 0, 09 0,678-0, 0,7880, 07880 0,788-0, RP=1, RP1 (RP=1, 1,0421, 10421 1,042-1,1 1,1681,2 11681 1,168-1,2 1,1541 1,154-1 RP=0 (RP=0 0,6780 0,678-0 0,7880 0,788-0 RP=1 (RP=1 1,0421 1,042-1, 1,1681, 1,168-1, 1,154- RP= (RP= 0,678- 0,788- 1,042-1 1,1681 1,168-1 (RP 1,042- 1,168-

Objective: to investigate the prevalence of skin lesions and factors associated with the use of N95 respirators among health professionals in Brazil. Method: cross-sectional study conducted with 11,368 health professionals using a respondent-driven sampling method adapted for online environments. Univariate and multivariate analyses were performed to investigate the association between the “skin lesions with the use of N95 respirators” variable and gender, professional category, workplace, training, COVID-19 diagnosis, and availability of sufficient and high-quality Personal Protective Equipment. Results: the prevalence of skin lesions was 61.8%. Women were 1.203 times (95% CI: 1.154-1.255) more likely to develop a lesion than men. The chances of skin lesions in psychologists (PR=0.805; 95% CI: 0.678-0.956) and dentists (PR=0.884; 95% CI: 0.788-0.992), were lower when compared to Nursing professionals. Professionals with a positive COVID-19 diagnosis and working in the Intensive Care Unit have an increased chance of presenting skin lesions (PR=1.074; 95% CI: 1.042-1.107); (PR=1.203; 95% CI: 1.168-1.241), respectively. Conclusion: the prevalence of skin lesions caused by the use of N95 respirators was 61.8% and was associated with female gender, professional category, workplace, training, COVID-19 diagnosis, and availability of sufficient and highquality Personal Protective Equipment. Objective N N9 Brazil Method crosssectional cross sectional 11368 11 368 11,36 respondentdriven respondent driven environments gender category workplace training COVID19 COVID 19 COVID-1 high quality Equipment Results 618 61 8 1203 1 203 1.20 95 (95 CI 1.1541.255 11541255 1.154 1.255 154 255 1.154-1.255 men PR=0.805 PR0805 PR 0 805 (PR=0.805 0.6780.956 06780956 0.678 0.956 678 956 0.678-0.956 PR=0.884 PR0884 884 (PR=0.884 0.7880.992, 07880992 0.788 0.992 , 788 992 0.788-0.992) PR=1.074 PR1074 074 (PR=1.074 1.0421.107 10421107 1.042 1.107 042 107 1.042-1.107) PR=1.203 PR1203 (PR=1.203 1.1681.241, 11681241 1.168 1.241 168 241 1.168-1.241) respectively Conclusion 61.8 1136 36 11,3 COVID1 COVID- 6 120 20 1.2 9 (9 1541 1.1541.25 1154125 1154 1.15 1255 1.25 15 25 1.154-1.25 PR=0.80 PR080 80 (PR=0.80 6780 0.6780.95 0678095 0678 0.67 0956 0.95 67 0.678-0.95 PR=0.88 PR088 88 (PR=0.88 7880 0.7880.992 0788099 0788 0.78 0992 0.99 78 99 0.788-0.992 PR=1.07 PR107 07 (PR=1.07 0421 1.0421.10 1042110 1042 1.04 1107 1.10 04 10 1.042-1.107 PR=1.20 PR120 (PR=1.20 1681 1.1681.241 1168124 1168 1.16 1241 1.24 16 24 1.168-1.241 61. 113 3 11, 12 2 1. ( 1.1541.2 115412 115 1.1 125 1.154-1.2 PR=0.8 PR08 (PR=0.8 0.6780.9 067809 067 0.6 095 0.9 0.678-0.9 0.7880.99 078809 078 0.7 099 7 0.788-0.99 PR=1.0 PR10 (PR=1.0 1.0421.1 104211 104 1.0 110 1.042-1.10 PR=1.2 PR12 (PR=1.2 1.1681.24 116812 116 124 1.168-1.24 1.1541. 11541 1.154-1. PR=0. PR0 (PR=0. 0.6780. 06780 06 0. 09 0.678-0. 0.7880.9 07880 0.788-0.9 PR=1. PR1 (PR=1. 1.0421. 10421 1.042-1.1 1.1681.2 11681 1.168-1.2 1.1541 1.154-1 PR=0 (PR=0 0.6780 0.678-0 0.7880. 0.788-0. PR=1 (PR=1 1.0421 1.042-1. 1.1681. 1.168-1. 1.154- PR= (PR= 0.678- 0.7880 0.788-0 1.042-1 1.1681 1.168-1 (PR 0.788- 1.042- 1.168-

Objetivo: investigar a prevalência de lesões de pele e fatores associados ao uso de respiradores N95 entre profissionais de saúde no Brasil. Método: estudo transversal realizado com 11.368 profissionais de saúde por meio de um método de amostragem dirigido por respondentes adaptado para ambientes online. Análises univariadas e multivariadas foram realizadas para investigar a associação entre a variável “lesão de pele com uso de respirador N95” e sexo, categoria profissional, local de trabalho, treinamento, diagnóstico de COVID-19 e disponibilidade suficiente de equipamentos de proteção individual de qualidade. Resultados: a prevalência de lesões cutâneas foi de 61,8%. As mulheres foram 1,203 vezes (IC 95%: 1.154-1.255) mais propensas a desenvolver uma lesão do que os homens. As chances de lesão de pele em psicólogos (RP=0,805; IC 95%: 0,678-0,956) e dentistas (RP=0,884; IC 95%: 0,788-0,992) foram menores quando comparados aos profissionais de Enfermagem. Profissionais com diagnóstico positivo para COVID-19 e que trabalham em Unidade de Cuidados Intensivos têm maior chance de apresentar lesões de pele (RP=1,074; IC 95%: 1,042-1,107); (RP=1,203; IC 95%: 1,168- 1,241), respectivamente. Conclusão: a prevalência de lesões de pele causadas pelo uso do respirador N95 foi de 61,8% e esteve associada ao sexo feminino, categoria profissional, local de trabalho, treinamento, diagnóstico de COVID-19 e disponibilidade suficiente de equipamentos de proteção individual de qualidade. Objetivo N N9 Brasil Método 11368 11 368 11.36 online profissional trabalho treinamento COVID19 COVID 19 COVID-1 qualidade Resultados 618 61 8 1203 1 203 1,20 95% 95 1.1541.255 11541255 1.154 1.255 154 255 1.154-1.255 homens RP=0,805 RP0805 RP 0 805 (RP=0,805 0,6780,956 06780956 0,678 0,956 678 956 0,678-0,956 RP=0,884 RP0884 884 (RP=0,884 0,7880,992 07880992 0,788 0,992 788 992 0,788-0,992 Enfermagem RP=1,074 RP1074 074 (RP=1,074 1,0421,107 10421107 1,042 1,107 042 107 1,042-1,107) RP=1,203 RP1203 (RP=1,203 1,168 1168 168 1,241, 1241 1,241 , 241 1,241) respectivamente Conclusão 61,8 feminino 1136 36 11.3 COVID1 COVID- 6 120 20 1,2 9 1541 1.1541.25 1154125 1154 1.15 1255 1.25 15 25 1.154-1.25 RP=0,80 RP080 80 (RP=0,80 6780 0,6780,95 0678095 0678 0,67 0956 0,95 67 0,678-0,95 RP=0,88 RP088 88 (RP=0,88 7880 0,7880,99 0788099 0788 0,78 0992 0,99 78 99 0,788-0,99 RP=1,07 RP107 07 (RP=1,07 0421 1,0421,10 1042110 1042 1,04 1107 1,10 04 10 1,042-1,107 RP=1,20 RP120 (RP=1,20 1,16 116 16 124 1,24 24 61, 113 3 11. 12 2 1, 1.1541.2 115412 115 1.1 125 1.2 1.154-1.2 RP=0,8 RP08 (RP=0,8 0,6780,9 067809 067 0,6 095 0,9 0,678-0,9 0,7880,9 078809 078 0,7 099 7 0,788-0,9 RP=1,0 RP10 (RP=1,0 1,0421,1 104211 104 1,0 110 1,1 1,042-1,10 RP=1,2 RP12 (RP=1,2 1.1541. 11541 1. 1.154-1. RP=0, RP0 (RP=0, 0,6780, 06780 06 0, 09 0,678-0, 0,7880, 07880 0,788-0, RP=1, RP1 (RP=1, 1,0421, 10421 1,042-1,1 1.1541 1.154-1 RP=0 (RP=0 0,6780 0,678-0 0,7880 0,788-0 RP=1 (RP=1 1,0421 1,042-1, 1.154- RP= (RP= 0,678- 0,788- 1,042-1 (RP 1,042-

SUMMARY OBJECTIVE: This study aimed to describe the current situation of sexual aggression and assess the adhesion to ambulatory care follow-up. METHODS: This is a cross-sectional study involving female children and adolescents aged 0–19 years, treated at the Center for Multiprofessional Care of Sexual Violence of the General Hospital of Nova Iguaçu, from 2014 to 2018. RESULTS: Of the 453 children and adolescents, 264 (58.3%) were <14 years of age and 189 (41.7%) were 14–19 years of age. In both groups, 78% were black. School delay of >2 years was found in 15.6% of children in the age group <14 years and 40.5% of adolescents in the age group 14–19 years [p<0.001; OR=3.7 (2.1–65)]. In girls aged £13 years, abuse usually occurred at home (73.2%), which was perpetrated by one aggressor (91%) and known to the victim (91.2%). In adolescents aged ≥14 years, 84.1% of rapes occurred outside the home, practiced by one aggressor (74.8%), 57.8% were unknown, and in 91.2% of cases, there was use of physical force and/or verbal threats. The victims aged <14 years have 14 times more chance of experiencing aggression within the family setting [p<0.001; OR=14.3 (8.2–25.6)] and 16 times more chance of experiencing aggression from known persons [p<0.001; OR=16.2 (9.2–29.8)]. On the contrary, adolescents aged ≥14 years have three times more chance of being abused by more than one aggressor [p<0.001; OR=3.3 (1.8–6.1)]. CONCLUSION: Black girls, especially those aged <14 years, are in a situation of greater vulnerability for sexual violence, have less adhesion to follow-up, and often experience aggression in the household setting. OBJECTIVE followup. followup follow up. up follow-up METHODS crosssectional cross sectional 019 0 19 0–1 Iguaçu 201 2018 RESULTS 45 26 58.3% 583 58 3 (58.3% <1 18 41.7% 417 41 7 (41.7% 1419 14–1 groups 78 black 2 > 156 15 6 15.6 405 40 5 40.5 p<0.001 p0001 p 001 [p<0.001 OR37 OR OR=3. 2.1–65. 2165 2.1–65 . 1 65 (2.1–65)] 13 £1 73.2%, 732 73.2% , 73 (73.2%) 91% 91 (91% 91.2%. 912 (91.2%) ≥1 841 84 84.1 74.8%, 748 74.8% 74 8 (74.8%) 578 57 57.8 unknown 91.2 cases andor or threats OR143 OR=14. 8.2–25.6 82256 25 (8.2–25.6) OR162 OR=16. 9.2–29.8. 92298 9.2–29.8 9 29 (9.2–29.8)] contrary OR33 1.8–6.1. 1861 1.8–6.1 (1.8–6.1)] CONCLUSION violence followup, up, 01 0– 20 4 58.3 (58.3 < 41.7 (41.7 141 14– 15. 40. p<0.00 p000 00 [p<0.00 OR3 OR=3 216 2.1–6 (2.1–65) £ 73.2 (73.2% (91 (91.2% ≥ 84. 74.8 (74.8% 57. 91. OR14 OR=14 8.2–25. 8225 (8.2–25.6 OR16 OR=16 9229 9.2–29. (9.2–29.8) 186 1.8–6. (1.8–6.1) 58. (58. 41. (41. p<0.0 p00 [p<0.0 OR= 21 2.1– (2.1–65 73. (73.2 (9 (91.2 74. (74.8 OR1 OR=1 8.2–25 822 (8.2–25. 922 9.2–29 (9.2–29.8 1.8–6 (1.8–6.1 (58 (41 p<0. p0 [p<0. 2.1 (2.1–6 (73. ( (91. (74. 8.2–2 82 (8.2–25 92 9.2–2 (9.2–29. 1.8– (1.8–6. (5 (4 p<0 [p<0 2. (2.1– (73 (74 8.2– (8.2–2 9.2– (9.2–29 1.8 (1.8–6 p< [p< (2.1 (7 8.2 (8.2– 9.2 (9.2–2 1. (1.8– [p (2. 8. (8.2 9. (9.2– (1.8 (2 (8. (9.2 (1. (8 (9. (1

This paper aims to explore the production of porous Nb2O5 pellets by pressing and adding anaerobic biomass (sludge) in order to evaluate the microstructure porosity. The thermal treatment temperature of the pellets varied between 300 ºC and 900 ºC. Their structural, morphological, and physical properties were measured, and the adsorption potential of Mn2+ and their reuse were evaluated. All samples had a monoclinic phase. Density average values of samples pressed using sludge ranged between 2.45 and 2.52 g.cm-3, while the one obtained without sludge pressing achieved higher values of around 2.72 g.cm-3. All samples presented high porosity values after the heat treatment (above 40%), which confirms the efficiency of sludge as a means to enhance porosity. These pellets were used for Mn2+ ions adsorption in aqueous medium. The Langmuir isotherm model was the one that achieved the best goodness-of-fit. In kinetic studies, the adsorption reaction was in accordance with second-order kinetics. Adsorbents in the form of pellets are environmentally friendly on account of their significant reuse and recycling potential. However, the particulate matter might become an environmental liability and incur high treatment costs. The samples proved to be reusable, promoting the adsorption of 67% of the Mn2+ after the fifth reuse cycle. NbO Nb O Nb2O (sludge 30 90 structural morphological measured Mn2 Mn evaluated phase 245 2 45 2.4 252 52 2.5 g.cm3, gcm3 gcm g.cm 3, g cm 3 g.cm-3 272 72 2.7 g.cm3. 3. above 40%, 40 40% , 40%) medium goodnessoffit. goodnessoffit goodness fit. fit goodness-of-fit studies secondorder second kinetics However costs reusable 67 cycle 9 24 4 2. 25 5 cm3 g.cm3 g.cm- 27 7 6