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au:Silva, Denise Rossato

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Audience response system smartphone application as an adjunct to tuberculosis teaching for medical students during the coronavirus disease 2019 pandemic
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Cabral, Vagner Kunz

; Cionek, Otávio Augusto Gonçalves Dias

; Loureiro, Marcelle Martinez

; Simbine, Rosa Elisa Bernardo

; Silva, Denise Rossato

Revista da Associação Médica Brasileira

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2024, Volume 70 N. 1 elocation e20231132

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVE: The growing availability of devices for mobile learning has created new opportunities for teaching. With the development of smartphone apps based on audience response systems, there is a possibility to quickly assess student knowledge. The education of health professionals, including medical students, is an essential strategy for tuberculosis control. In the context of the coronavirus disease 2019 pandemic, audience response systems are very useful as online assessment tools. The aim of this study was to use the audience response systems Socrative to assess medical students during a class on tuberculosis. METHODS: This is a quasi-experimental before-and-after study, with pre- and post-tests carried out through the Socrative app, respectively, before and after a lecture on tuberculosis for medical students. Also, a cross-sectional study was carried out after the course to evaluate the participant's satisfaction through an electronic, structured questionnaire with a Likert-type scale. RESULTS: A total of 126 students were included in the study. The overall mean pre- and post-test scores were 5.98±1.59 and 8.37±1.36, respectively, with a statistically significant difference (p<0.0001). Almost all students were totally satisfied with the use of Socrative on pre- and post-tests. CONCLUSION: This study describes how the use of Socrative in a tuberculosis class was well received by students. In addition, the baseline knowledge on tuberculosis was low in some topics, with some improvement after the lecture. These findings emphasize the need to further improve the students’ knowledge on tuberculosis and help instructors customize the lecture based on the gaps identified in the Socrative assessment.

https://doi.org/10.1590/1806-9282.20231132

Migration and medical screening for tuberculosis
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Silva, Denise Rossato

; Mello, Fernanda Carvalho de Queiroz

; Johansen, Fernanda Dockhorn Costa

; Centis, Rosella

; D’Ambrosio, Lia

; Migliori, Giovanni Battista

Jornal Brasileiro de Pneumologia

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2023, Volume 49 N. 2 elocation e20230051

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Vulnerable populations, such as migrants and refugees, have an increased risk of tuberculosis disease, especially in the first years after arrival in the host country. The presence of migrants and refugees in Brazil exponentially grew over the period between 2011 and 2020, and approximately 1.3 million migrants from the Global South were estimated to be residing in Brazil, most of whom from Venezuela and Haiti. Tuberculosis control programs for migrants can be divided into pre- and post-migration screening strategies. Pre-migration screening aims to identify cases of tuberculosis infection (TBI) and can be carried out in the country of origin (pre-entry) or in the destination country (at entry). Pre-migration screening can also detect migrants at an increased risk of developing tuberculosis in the future. High-risk migrants are then followed up in post-migration screening. In Brazil, migrants are considered a priority group for the active search for tuberculosis cases. However, there is no recommendation or plan regarding screening for TBI in migrants and refugees. Ensuring prevention, diagnosis, and treatment for TBI and tuberculosis disease in migrant populations is an important aspect of tuberculosis control and elimination. In this review article, we address epidemiological aspects and access to health care for migrants in Brazil. In addition, the migration medical screening for tuberculosis was reviewed.

RESUMO Populações vulneráveis, como imigrantes e refugiados, apresentam maior risco de tuberculose doença, especialmente nos primeiros anos após a chegada ao país de acolhimento. A presença de imigrantes e refugiados no Brasil cresceu exponencialmente no período entre 2011 e 2020, sendo estimado que aproximadamente 1,3 milhão de imigrantes do Sul Global residiam no Brasil, a maioria proveniente da Venezuela e do Haiti. Os programas de controle da tuberculose para imigrantes podem ser divididos em estratégias de triagem pré- e pós-migração. A triagem pré-migração visa identificar casos de tuberculose infecção (TBI) e pode ser realizada no país de origem (pré-entrada) ou no país de destino (no momento da entrada). A triagem pré-migração também pode detectar imigrantes com maior risco de desenvolver tuberculose no futuro. Os imigrantes de alto risco são então acompanhados na triagem pós-migração. No Brasil, os imigrantes são considerados um grupo prioritário para a busca ativa de casos de tuberculose. No entanto, não há recomendação ou plano sobre triagem para TBI em imigrantes e refugiados. Garantir a prevenção, o diagnóstico e o tratamento da TBI e da tuberculose doença em populações imigrantes é um aspecto importante do controle e eliminação da tuberculose. Neste artigo de revisão, abordamos aspectos epidemiológicos e acesso à saúde para imigrantes no Brasil. Além disso, revisou-se a triagem médica de imigrantes para tuberculose.

https://doi.org/10.36416/1806-3756/e20230051

Severe acute respiratory syndrome coronavirus 2 seroprevalence among patients with pulmonary tuberculosis
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Dias, Natan José Dutra

; Silva, Maiana Silva da

; Barbosa, Márcia Silva

; Pereira, Giovana Rodrigues

; Silva, Denise Rossato

Revista da Associação Médica Brasileira

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2023, Volume 69 N. 9 elocation e20230661

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVE: The objective of this study was to estimate the seroprevalence of severe acute respiratory syndrome coronavirus 2 antibodies in patients with tuberculosis. METHODS: This cross-sectional study was conducted at an outpatient tuberculosis clinic in Alvorada, RS, Brazil, with data collection between October and December 2020. Outpatients aged>18 years with active pulmonary tuberculosis, no prior history of coronavirus disease 2019, and no suspected coronavirus disease 2019 were included in the study. Whole blood samples were collected to perform the severe acute respiratory syndrome coronavirus 2 antibodies test. RESULTS: During the study period, 52 patients met the inclusion and were included in the analysis. Severe acute respiratory syndrome coronavirus 2 antibodies were positive in 16 (30.8%) patients. Male sex was more frequent among patients with negative severe acute respiratory syndrome coronavirus 2 antibodies than in patients with positive severe acute respiratory syndrome coronavirus 2 antibodies (86.1 vs. 56.3%, p=0.031). Contact with coronavirus disease 2019 case was more common in patients with positive severe acute respiratory syndrome coronavirus 2 antibodies compared with patients with negative severe acute respiratory syndrome coronavirus 2 antibodies (87.5 vs. 8.3%, p<0.0001). In a multivariate analysis, in a model including the variables such as male sex and contact with coronavirus disease 2019 case, only contact with coronavirus disease 2019 was independently associated with positive severe acute respiratory syndrome coronavirus 2 antibodies (OR 77.0, 95%CI 11.5–512.4, p<0.0001). CONCLUSION: This study revealed a seroprevalence of 30.8% severe acute respiratory syndrome coronavirus 2 among patients with tuberculosis.

https://doi.org/10.1590/1806-9282.20230661

Effect of vaccination on COVID-19 hospitalizations and mortality
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Dantas Filho, Fábio Fernandes

; D’Ávila, Karen Gomes

; Silva, Denise Rossato

Jornal Brasileiro de Pneumologia

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2023, Volume 49 N. 4 elocation e20230254

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36416/1806-3756/e20230254

Brazilian Thoracic Association recommendations for the management of post-tuberculosis lung disease
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Silva, Denise Rossato

; Santos, Ana Paula

; Visca, Dina

; Bombarda, Sidney

; Dalcolmo, Margareth Maria Pretti

; Galvão, Tatiana

; Miranda, Silvana Spíndola de

; Parente, Ana Alice Amaral Ibiapina

; Rabahi, Marcelo Fouad

; Sales, Roberta Karla Barbosa de

; Migliori, Giovanni Battista

; Mello, Fernanda Carvalho de Queiroz

Jornal Brasileiro de Pneumologia

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2023, Volume 49 N. 6 elocation e20230269

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Historically, all efforts against tuberculosis were focused on rapid diagnosis and effective treatment to break the chain of transmission of Mycobacterium tuberculosis. However, in the last few years, more and more evidence has been found on the dramatic consequences of the condition defined as post-tuberculosis lung disease (PTLD). Approximately one third of patients surviving pulmonary tuberculosis face considerable ongoing morbidities, including respiratory impairment, psychosocial challenges, and reduced health-related quality of life after treatment completion. Given the important global and local burden of tuberculosis, as well as the estimated burden of PTLD, the development of a consensus document by a Brazilian scientific society-Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)-was considered urgent for the prevention and management of this condition in order to allocate resources to and within tuberculosis services appropriately and serve as a guide for health care professionals. A team of eleven pulmonologists and one methodologist was created by the SBPT to review the current evidence on PTLD and develop recommendations adapted to the Brazilian context. The expert panel selected the topics on the basis of current evidence and international guidelines. During the first phase, three panel members drafted the recommendations, which were divided into three sections: definition and prevalence of PTLD, assessment of PTLD, and management of PTLD. In the second phase, all panel members reviewed, discussed, and revised the recommendations until a consensus was reached. The document was formally approved by the SBPT in a special session organized during the 2023 SBPT Annual Conference.

RESUMO Historicamente, todos os esforços contra a tuberculose concentraram-se no diagnóstico rápido e no tratamento efetivo para quebrar a cadeia de transmissão do Mycobacterium tuberculosis. No entanto, nos últimos anos, têm sido encontradas mais e mais evidências sobre as dramáticas consequências da condição definida como doença pulmonar pós-tuberculose (DPPT). Aproximadamente um terço dos pacientes que sobrevivem à tuberculose pulmonar enfrenta morbidades consideráveis e persistentes, incluindo comprometimento respiratório, desafios psicossociais e redução da qualidade de vida relacionada à saúde após o término do tratamento. Diante da importante carga global e local da tuberculose, bem como da carga estimada da DPPT, considerou-se urgente o desenvolvimento de um documento de consenso por uma sociedade científica brasileira - a Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) - para a prevenção e manejo dessa condição, a fim de alocar recursos de forma adequada para e nos serviços de tuberculose e servir de guia para os profissionais de saúde. Uma equipe de onze pneumologistas e um metodologista foi criada pela SBPT para revisar as evidências atuais sobre a DPPT e desenvolver recomendações adaptadas ao contexto brasileiro. O painel de especialistas selecionou os temas com base nas evidências atuais e diretrizes internacionais. Durante a primeira fase, três membros do painel redigiram as recomendações, que foram divididas em três seções: definição e prevalência de DPPT, avaliação da DPPT e manejo da DPPT. Na segunda fase, todos os membros do painel analisaram, discutiram e revisaram as recomendações até chegar a um consenso. O documento foi aprovado formalmente pela SBPT em sessão especial organizada durante o Congresso Anual da SBPT de 2023.

https://doi.org/10.36416/1806-3756/e20230269

Diagnosis and management of post-tuberculosis lung disease posttuberculosis post tuberculosis
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Silva, Denise Rossato

; Mello, Fernanda Carvalho de Queiroz

; Migliori, Giovanni Battista

Jornal Brasileiro de Pneumologia

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2023, Volume 49 N. 2 elocation e20230055

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36416/1806-3756/e20230055

Adjunctive corticosteroid therapy in patients with pulmonary tuberculosis
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Lemos, Carolina Xavier

; Anton, Camila

; Machado, Felipe Dominguez

; Bernardi, Rafaela Manzoni

; Freitas, Alana Ambos

; Silva, Denise Rossato

Revista da Associação Médica Brasileira

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sep 2022, Volume 68 N. 9 Pages 1199 - 1203

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVES: In tuberculosis treatment, corticosteroids are used as adjuvants, especially in meningeal/pericardial tuberculosis. In other forms of the disease, especially in severe tuberculosis requiring mechanical ventilation, its use is controversial. The aim of the present study is to assess whether the use of corticosteroids in the treatment of pulmonary tuberculosis patients in mechanical ventilation is associated with in-hospital mortality. METHODS: This is a retrospective cohort study. Tuberculosis patients >18 years requiring mechanical ventilation, admitted to the emergency department or intensive care unit, were included. Data on corticosteroid use and mortality were collected. RESULTS: In total, 467 patients were included in the analysis; 399 used corticosteroids and 68 were noncorticosteroid users. The mortality rate was higher among corticosteroid users (59.9%) than in noncorticosteroid users (41.2%) (p=0.010). The total dose of corticosteroid in prednisone equivalents was not different between survivors and nonsurvivors (median [interquartile range]: 80 mg [5–56.6 mg] vs. 80 mg [50–135 mg]; p=0.881). CONCLUSIONS: Tuberculosis patients in mechanical ventilation who used corticosteroids had a higher mortality rate than those who did not use corticosteroids. The role of corticosteroids in pulmonary tuberculosis, especially in critically ill patients, remains unclear and needs further evaluation in prospective studies.

https://doi.org/10.1590/1806-9282.20220196

Country-specific lockdown measures in response to the COVID-19 pandemic and its impact on tuberculosis control: a global study
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Migliori, Giovanni Battista

; Thong, Pei Min

; Alffenaar, Jan-Willem

; Denholm, Justin

; Tadolini, Marina

; Alyaquobi, Fatma

; Al-Abri, Seif

; Blanc, François-Xavier

; Buonsenso, Danilo

; Chakaya, Jeremiah

; Cho, Jin-Gun

; Codecasa, Luigi Ruffo

; Danila, Edvardas

; Duarte, Raquel

; Dukpa, Rada

; García-García, José-María

; Gualano, Gina

; Kurhasani, Xhevat

; Manika, Katerina

; Mello, Fernanda Carvalho de Queiroz

; Pahl, Kristin

; Rendon, Adrian

; Sotgiu, Giovanni

; Souleymane, Mahamadou Bassirou

; Thomas, Tania A.

; Tiberi, Simon

; Kunst, Heinke

; Udwadia, Zarir F.

; Goletti, Delia

; Centis, Rosella

; D’Ambrosio, Lia

; Silva, Denise Rossato

Jornal Brasileiro de Pneumologia

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2022, Volume 48 N. 2 elocation e20220087

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo deste estudo foi descrever as medidas de confinamento específicas de cada país e os indicadores de tuberculose coletados durante o primeiro ano da pandemia de COVID-19. Dados referentes a confinamento/restrições sociais (uso obrigatório de máscaras faciais e higiene obrigatória das mãos; restrições a viagens internacionais e locais; restrições a visitas familiares e fechamento das escolas) foram coletados de 24 países em cinco continentes. A maioria dos países implantou múltiplos confinamentos, com reabertura parcial ou total. Houve uma redução geral dos casos de tuberculose ativa, tuberculose resistente e tuberculose latente. Embora os confinamentos nacionais tenham sido eficazes na contenção dos casos de COVID-19, vários indicadores de tuberculose foram afetados durante a pandemia.

ABSTRACT The objective of this study was to describe country-specific lockdown measures and tuberculosis indicators collected during the first year of the COVID-19 pandemic. Data on lockdown/social restrictions (compulsory face masks and hand hygiene; international and local travel restrictions; restrictions to family visits, and school closures) were collected from 24 countries spanning five continents. The majority of the countries implemented multiple lockdowns with partial or full reopening. There was an overall decrease in active tuberculosis, drug-resistant tuberculosis, and latent tuberculosis cases. Although national lockdowns were effective in containing COVID-19 cases, several indicators of tuberculosis were affected during the pandemic.

https://doi.org/10.36416/1806-3756/e20220087

Effects of COVID-19 on tuberculosis control: past, present, and future
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Silva, Denise Rossato

; Mello, Fernanda Carvalho de Queiroz

; Migliori, Giovanni Battista

Jornal Brasileiro de Pneumologia

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2022, Volume 48 N. 2 elocation e20220102

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36416/1806-3756/e20220102

10.

Post-tuberculosis lung disease: a comparison of Brazilian, Italian, and Mexican cohorts
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Silva, Denise Rossato

; Freitas, Alana Ambos

; Guimarães, Amanda Reis

; D’Ambrosio, Lia

; Centis, Rosella

; Muñoz-Torrico, Marcela

; Visca, Dina

; Migliori, Giovanni Battista

Jornal Brasileiro de Pneumologia

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2022, Volume 48 N. 2 elocation e20210515

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar a função pulmonar em uma coorte de pacientes com história de tuberculose pulmonar no Brasil, bem como avaliar o declínio da função pulmonar ao longo do tempo e compará-lo com o observado em coortes semelhantes no México e Itália. Métodos: As três coortes foram comparadas quanto à idade, tabagismo, testes de função pulmonar, teste de caminhada de seis minutos e gasometria arterial. Na coorte brasileira, os resultados dos testes de função pulmonar, do teste de caminhada de seis minutos e da gasometria arterial logo após o término do tratamento da tuberculose foram comparados com os obtidos no fim do período de acompanhamento. Resultados: As três coortes foram muito diferentes quanto aos resultados dos testes de função pulmonar. Os padrões ventilatórios mais comuns nas coortes brasileira, italiana e mexicana foram o padrão obstrutivo, o padrão misto e o padrão normal [em 58 pacientes (50,9%), em 18 pacientes (41,9%) e em 26 pacientes (44,1%), respectivamente]. Apenas 2 casos de tuberculose multirresistente foram incluídos na coorte brasileira, ao passo que na coorte mexicana foram incluídos 27 casos (45,8%). As médias da PaO2 e SaO2 foram mais baixas na coorte mexicana do que na brasileira (p < 0,0001 e p < 0,002 para PaO2 e SaO2, respectivamente). Na coorte brasileira, quase todos os parâmetros funcionais se deterioraram ao longo do tempo. Conclusões: Este estudo reforça a importância do tratamento precoce e eficaz de pacientes com tuberculose sensível, pois a tuberculose multirresistente aumenta o dano pulmonar. Quando o tratamento da tuberculose é concluído, os pacientes devem ser avaliados o quanto antes e, caso se estabeleça o diagnóstico de sequelas pulmonares da tuberculose, é preciso tratá-los e oferecer-lhes reabilitação pulmonar, pois há evidências de que ela é eficaz nesses pacientes.

ABSTRACT Objective: To evaluate lung function in a cohort of patients with a history of pulmonary tuberculosis in Brazil, as well as to evaluate the decline in lung function over time and compare it with that observed in similar cohorts in Mexico and Italy. Methods: The three cohorts were compared in terms of age, smoking status, pulmonary function test results, six-minute walk test results, and arterial blood gas results. In the Brazilian cohort, pulmonary function test results, six-minute walk test results, and arterial blood gas results right after the end of tuberculosis treatment were compared with those obtained at the end of the follow-up period. Results: The three cohorts were very different regarding pulmonary function test results. The most common ventilatory patterns in the Brazilian, Italian, and Mexican cohorts were an obstructive pattern, a mixed pattern, and a normal pattern (in 58 patients [50.9%], in 18 patients [41.9%], and in 26 patients [44.1%], respectively). Only 2 multidrug-resistant tuberculosis cases were included in the Brazilian cohort, whereas, in the Mexican cohort, 27 cases were included (45.8%). Mean PaO2 and mean SaO2 were lower in the Mexican cohort than in the Brazilian cohort (p < 0.0001 and p < 0.002 for PaO2 and SaO2, respectively). In the Brazilian cohort, almost all functional parameters deteriorated over time. Conclusions: This study reinforces the importance of early and effective treatment of drug-susceptible tuberculosis patients, because multidrug-resistant tuberculosis increases lung damage. When patients complete their tuberculosis treatment, they should be evaluated as early as possible, and, if post-tuberculosis lung disease is diagnosed, they should be managed and offered pulmonary rehabilitation because there is evidence that it is effective in these patients.

https://doi.org/10.36416/1806-3756/e20210515

11.

Smoking prevalence and effects on treatment outcomes in patients with tuberculosis
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de Vargas, Kellyn Rocha

; Freitas, Alana Ambos

; Azeredo, Ana Cláudia Vasconcellos

; Silva, Denise Rossato

Revista da Associação Médica Brasileira

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mar 2021, Volume 67 N. 3 Pages 406 - 410

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVE: More than 20% of tuberculosis (TB) cases worldwide are attributable to smoking, and it is associated with an increased risk of latent and active TB, recurrence, and mortality. The aim of this study is to assess the smoking prevalence and the effects on treatment outcomes in TB patients. METHODS: A prospective cohort study was conducted in patients with a recent TB diagnosis. The smoking status was defined, in addition to the patients’ knowledge and attitudes toward smoking. The patients were followed up until the end of the treatment, and the treatment result was recorded. RESULTS: Ninety-two patients were included in this study. The prevalence of active smoking was 31.5%. Active smokers had less chance for cure (62.1% versus 82.5%; p=0.032) and more treatment dropout (31.0% versus 12.7%; p=0.035) than non-active smokers. Patients demonstrated positive attitudes and good knowledge about smoking. CONCLUSIONS: Active smokers had less chance for cure and more abandonment than non-active smokers. These results can be useful for the proper planning of actions that impact TB control, especially in the treatment results, such as cognitive-behavioral approaches to smoking cessation.

https://doi.org/10.1590/1806-9282.20200825 54 downloads

12.

Association between Xpert MTB/RIF cycle threshold values and sputum smear microscopy in patients with pulmonary tuberculosis
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Pagano, Gabriela Carpin

; Pereira, Giovana Rodrigues

; D’Ávila, Karen Gomes

; Monaiar, Luciana Rott

; Silva, Denise Rossato

Jornal Brasileiro de Pneumologia

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2021, Volume 47 N. 2 elocation e20200549

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36416/1806-3756/e20200549 323 downloads

13.

Diagnosis of tuberculosis: a consensus statement from the Brazilian Thoracic Association
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Silva, Denise Rossato

; Rabahi, Marcelo Fouad

; Sant’Anna, Clemax Couto

; Silva-Junior, José Laerte Rodrigues da

; Capone, Domenico

; Bombarda, Sidney

; Miranda, Silvana Spíndola de

; Rocha, Jorge Luiz da

; Dalcolmo, Margareth Maria Pretti

; Rick, Mônica Flores

; Santos, Ana Paula

; Dalcin, Paulo de Tarso Roth

; Galvão, Tatiana Senna

; Mello, Fernanda Carvalho de Queiroz

Jornal Brasileiro de Pneumologia

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2021, Volume 47 N. 2 elocation e20210054

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O diagnóstico precoce e adequado da tuberculose é um dos pilares mais importantes no controle da doença. A proposta deste consenso brasileiro é apresentar aos profissionais da área de saúde um documento com as evidências mais atuais e úteis para o diagnóstico da tuberculose. Para tanto, a Comissão de Tuberculose da Sociedade Brasileira de Pneumologia e Tisiologia reuniu 14 membros da Sociedade com reconhecida experiência em tuberculose no Brasil. Foi realizada uma revisão não sistemática dos seguintes tópicos: diagnóstico clínico, diagnóstico bacteriológico, diagnóstico radiológico, diagnóstico histopatológico, diagnóstico da tuberculose na criança e diagnóstico da tuberculose latente.

ABSTRACT Early, accurate diagnosis of tuberculosis is one of the major pillars of the control of the disease. The purpose of this consensus statement is to provide health professionals with the most current, useful evidence for the diagnosis of tuberculosis in Brazil. To that end, the Tuberculosis Committee of the Brazilian Thoracic Association brought together 14 members of the Association with recognized expertise in tuberculosis in Brazil to compose the statement. A nonsystematic review of the following topics was carried out: clinical diagnosis, bacteriological diagnosis, radiological diagnosis, histopathological diagnosis, diagnosis of tuberculosis in children, and diagnosis of latent tuberculosis infection.

https://doi.org/10.36416/1806-3756/e20210054 348 downloads

14.

Tuberculosis Series 2021
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Silva, Denise Rossato

; Mello, Fernanda Carvalho de Queiroz

; Migliori, Giovanni Battista

Jornal Brasileiro de Pneumologia

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2021, Volume 47 N. 2 elocation e20210109

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36416/1806-3756/e20210109 531 downloads

15.

Tuberculosis and COVID-19, the new cursed duet: what differs between Brazil and Europe?
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Silva, Denise Rossato

; Mello, Fernanda Carvalho de Queiroz

; D’Ambrosio, Lia

; Centis, Rosella

; Dalcolmo, Margareth Pretti

; Migliori, Giovanni Battista

Jornal Brasileiro de Pneumologia

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2021, Volume 47 N. 2 elocation e20210044

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Em 1º de abril de 2020, a COVID-19 ultrapassou a tuberculose em número de óbitos por dia no mundo. A associação da tuberculose com a COVID-19 apresenta grande potencial de morbidade e mortalidade. Além disso, a pandemia de COVID-19 tem tido um impacto significativo no diagnóstico e tratamento da tuberculose. Neste artigo de revisão, abordamos tuberculose e COVID-19 concomitantes, com particular atenção às diferenças entre Brasil e Europa. Além disso, discutimos as prioridades em atendimento clínico, saúde pública e pesquisa.

ABSTRACT On April 1st, 2020, COVID-19 surpassed tuberculosis regarding the number of deaths per day worldwide. The combination of tuberculosis and COVID-19 has great potential for morbidity and mortality. In addition, the COVID-19 pandemic has had a significant impact on the diagnosis and treatment of tuberculosis. In this review article, we address concurrent tuberculosis and COVID-19, with particular regard to the differences between Brazil and Europe. In addition, we discuss priorities in clinical care, public health, and research.

https://doi.org/10.36416/1806-3756/e20210044 956 downloads

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