Objective: To translate, adapt, and examine the factor structure and internal consistency of a Brazilian Portuguese version of the Smartphone Addiction Scale (SAS-BR) among university students. Methods: The SAS was translated and adapted for use with Brazilian samples. The resulting instrument (SAS-BR) was then administered to 356 college students. Parallel analysis was used to explore the maximum number of dimensions that underlie the assessment, and data modeling was undertaken using exploratory multidimensional item response theory (E-MIRT). The reliability of the SAS-BR was tested by computing McDonald’s omega (ω) and Cronbach’s alpha (α) coefficients. Results: Parallel analysis revealed a maximum of six factors. E-MIRT analysis revealed that a five-factor model was the best fit for the data. The five emergent factors were salience, positive anticipation, cyberspace-oriented relationship, preoccupation with smartphone, and physical symptoms; these factors together explained 50% of the variance. Confirmatory factor analysis, conducted using data from a second sample, replicated the five-factor structure. The internal consistency of the scale was found to be strong. Conclusion: The emergent factor structure of the SAS-BR was found to be similar to that of previous adaptations of this instrument for other Western countries.