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Abstract Background Evaluation and treatment of primary and secondary headaches is a global public health challenge. Recognizing the epidemiological impact of headaches, a group of researchers linked to the Brazilian Headache Society proposed the Brazilian Headache Registry and drew up its initial protocol. Objective Here we describe the methods and preliminary data obtained from the pilot study. Methods This was a multicenter longitudinal observational study conducted between September 2020 and August 2021. Prospective data were collected in three specialist centers for headache care in states in southern and southeastern Brazil. Patients aged 18 years or older who sought care for headache in tertiary centers and who agreed to participate in the study, were considered eligible. Results Sixty-six patients were included in the pilot study: 43 (65%) from Rio Grande do Sul state and 23 (35%) from Minas Gerais state. Overall, 90% were female, and the subjects' mean age was 38.2 ± 11.2 years. Primary headaches accounted for 85.3% of the diagnoses made. Among secondary headaches, medication overuse headache was the most frequent type (7.1%). Conclusions The pilot study showed the feasibility of the research protocol developed for tertiary centers. The Brazilian Headache Registry will form a source of longitudinal data with the aim of contributing to better characterization of the various phenotypes of patients with primary and secondary headaches, and to detailing the use of health resources and identifying predictors of better clinical outcomes.

Resumo Antecedentes A avaliação e o tratamento das cefaleias primárias e secundárias são um desafio global de saúde pública. Reconhecendo o impacto epidemiológico das cefaleias, um grupo de pesquisadores vinculados à Sociedade Brasileira de Cefaleia propôs a criação de um Registro Brasileiro de Cefaleia e elaborou seu protocolo inicial. Objetivo Nesta publicação descrevemos os métodos e dados preliminares obtidos a partir do estudo piloto. Métodos Trata-se de um estudo prospectivo observacional longitudinal multicêntrico, realizado entre setembro de 2020 e agosto de 2021. Foram coletados dados em três centros especializados no atendimento de cefaleia, em estados da região sul e sudeste do Brasil. Pacientes com idade igual ou superior a 18 anos que procuraram os centros terciários por queixa de cefaleia e concordaram em participar do estudo foram considerados elegíveis. Resultados Sessenta e seis pacientes foram incluídos no estudo piloto, 43 (65%) do Rio Grande do Sul e 23 (35%) de Minas Gerais. Da amostra total, 90% eram do sexo feminino e a idade média dos sujeitos foi de 38,2 ± 11,2 anos. As cefaleias primárias representaram 85,3% dos diagnósticos realizados. Entre as cefaleias secundárias, a cefaleia por uso excessivo de medicamentos foi a mais frequente (7,1%). Conclusões O estudo piloto evidenciou a viabilidade do protocolo de pesquisa desenvolvido para centros terciários. O Registro Brasileiro de Cefaleia constituirá uma fonte de dados longitudinais com o objetivo de contribuir para melhor caracterização dos diversos fenótipos de pacientes com cefaleias primárias e secundárias, detalhar o uso de recursos de saúde e identificar preditores de melhores desfechos clínicos.

https://doi.org/10.1055/s-0043-1771175

Sexually Transmitted Infections Lesions Found during Colonoscopies
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Gomes, Alexandre

; Sampaio Netto, João Batista

; Ayres, Ricardo de Oliveira

; Rodrigues, José Mauro da Silva

; Borghesi, Ronaldo Antonio

Journal of Coloproctology (Rio de Janeiro)

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jun 2023, Volume 43 N. 2 Pages 75 - 81

Abstract: En | Text: En | PDF: En

Abstract Introduction Anal examination and videoanoscopy (VA) are rarely performed during colonoscopies. In recent years, there has been a considerable increase in lesions of sexually transmitted anal and rectal infections, but these conditions are not noticed or reported during routine colonoscopy. Objective To raise awareness regarding the fortuitous findings of lesions and sexually transmitted infections (STIs) in colonoscopy exams and to demonstrate that anal examination and VA provide important information and should be routinely performed. Methods We conducted a descriptive retrospective study in 16,132 patients screened by colonoscopy and VA between 2006 and 2018. Among numerous other findings, the presence of anal condylomata and sexually transmitted retitis or perianal dermatitis was observed. The rates of each finding were calculated, and the patients were subdivided by sex and into age groups by blocks of ten years. Results Among the 16,132 colonoscopies performed, 26 cases of condyloma (0.16%) and 50 cases of proctitis or perianal dermatitis suspicious for STI (0.33%) were found. Conclusion Performing anal examination and VA systematically in all routine colonoscopies enabled the identification of numerous anal conditions, including several fortuitous cases of STIs. The study proposes that anal examination and VA should be performed in all routine colonoscopies and, in suspected cases, complementary tests for STIs.

https://doi.org/10.1055/s-0043-1769486

Genital ulcers caused by sexually transmitted agents,
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Cunha Ramos, Mauro

; Nicola, Maria Rita Castilhos

; Bezerra, Natália Tenório Cavalcante

; Sardinha, José Carlos Gomes

; Morais, Julia Sampaio de Souza

; Schettini, Antônio Pedro

Anais Brasileiros de Dermatologia

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oct 2022, Volume 97 N. 5 Pages 551 - 565

Abstract: En | Text: En | PDF: En

Abstract Genital ulcers (GUs) represent a diagnostic challenge and can be secondary to neoplastic and inflammatory processes of different causes. Among those of infectious etiology, there are sexually transmitted infections (STIs), a very frequent reason for seeking the health service. The most common agents are herpes simplex virus and Treponema pallidum and, more rarely, Haemophilus ducreyi, Klebsiella granulomatis and Chlamydia trachomatis. A careful dermatological examination offers important diagnostic elements; however, atypical manifestations are very common. Distinctive characteristics of ulcers to look out for include their margin, edge, bottom, and base. Regional lymph node chain alterations should be evaluated regarding their number, size, mobility, consistency, inflammation, and pain on palpation. Diagnostic tests have variable sensitivity and specificity, and molecular tests are currently considered the reference exams. The rapid immunochromatographic tests represented a significant advance, as they can be performed with blood obtained from the digital pulp, offer results in up to 30 minutes, and do not require a laboratory structure. The treatment of persons affected by GU/STIs must be immediate, as it aims to prevent complications, as well as reduce transmission. It is not always considered that people with GUs/STIs have varying degrees of depression, anxiety, and self-reproach, with an impact on relationships. Establishing a bond and trusting the professional is essential for adherence to treatment and preventive measures that must be discussed individually.

https://doi.org/10.1016/j.abd.2022.01.004

Consensus of the Brazilian Headache Society (SBCe) for prophylactic treatment of episodic migraine: part II
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Santos, Paulo Sergio Faro

; Melhado, Eliana Meire

; Kaup, Alexandre Ottoni

; Costa, Aline Turbino Neves Martins da

; Roesler, Célia Aparecida de Paula

; Piovesan, Élcio Juliato

; Sarmento, Elder Machado

; Theotonio, Giselle Oliveira Martins

; Campos, Henrique Carneiro de

; Fortini, Ida

; Souza, Jano Alves de

; Maciel Júnior, Jayme Antunes

; Segundo, João Batista Alves

; Carvalho, João José Freitas de

; Speziali, José Geraldo

; Calia, Leandro Cortoni

; Barea, Liselotte Menke

; Queiroz, Luiz Paulo

; Souza, Marcio Nattan Portes

; Figueiredo, Marcos Ravi Cerqueira Ferreira

; Costa, Maria Eduarda Nobre de Magalhães

; Peres, Mário Fernando Prieto

; Jurno, Mauro Eduardo

; Peixoto, Patrícia Machado

; Kowacs, Pedro André

; Rocha Filho, Pedro Augusto Sampaio

; Moreira Filho, Pedro Ferreira

; Silva Neto, Raimundo Pereira

; Fragoso, Yara Dadalti

Arquivos de Neuro-Psiquiatria

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sep 2022, Volume 80 N. 9 Pages 953 - 969

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Migraine affects 1 billion people worldwide and > 30 million Brazilians; besides, it is an underdiagnosed and undertreated disorder. Objective The need to disseminate knowledge about the prophylactic treatment of migraine is known, so the Brazilian Headache Society (SBCe, in the Portuguese acronym) appointed a committee of authors with the objective of establishing a consensus with recommendations on the prophylactic treatment of episodic migraine based on articles from the world literature as well as from personal experience. Methods Meetings were held entirely online, with the participation of 12 groups that reviewed and wrote about the pharmacological categories of drugs and, at the end, met to read and finish the document. The drug classes studied in part II of this Consensus were: antihypertensives, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, calcium channel blockers, other drugs, and rational polytherapy. Results From this list of drugs, only candesartan has been established as effective in controlling episodic migraine. Flunarizine, venlafaxine, duloxetine, and pizotifen were defined as likely to be effective, while lisinopril, enalapril, escitalopram, fluvoxamine, quetiapine, atorvastatin, simvastatin, cyproheptadine, and melatonin were possibly effective in prophylaxis of the disease. Conclusions Despite an effort by the scientific community to find really effective drugs in the treatment of migraine, given the large number of drugs tested for this purpose, we still have few therapeutic options.

Resumo Antecedentes Migrânea afeta um bilhão de pessoas em todo o mundo e mais de 30 milhões de brasileiros; além disso, é um distúrbio subdiagnosticado e subtratado. Objetivo Sabe-se sobre a necessidade de difundir o conhecimento sobre o tratamento profilático da migrânea; por isso, a Sociedade Brasileira de Cefaleias (SBCe) nomeou um comitê de autores com o objetivo de estabelecer um consenso com recomendações sobre o tratamento profilático da migrânea episódica com base em artigos da literatura mundial, assim como da experiência pessoal. Métodos As reuniões foram realizadas inteiramente online, com a participação de 12 grupos que revisaram e escreveram sobre as categorias farmacológicas dos medicamentos e, ao final, reuniram-se para a leitura e conclusão do documento. As classes de medicamentos estudadas na parte II deste Consenso foram: anti-hipertensivos, inibidores seletivos de recaptação de serotonina, inibidores de recaptação de serotonina e noradrenalina, bloqueadores dos canais de cálcio, outros medicamentos e politerapia racional. Resultados Desta lista de medicamentos, apenas o candesartan foi estabelecido como eficaz no controle da migrânea episódica. Flunarizina, venlafaxina, duloxetina e pizotifeno foram definidos como provavelmente eficazes, enquanto lisinopril, enalapril, escitalopram, fluvoxamina, quetiapina, atorvastatina, sinvastatina, ciproheptadina e melatonina foram possivelmente eficazes na profilaxia da doença. Conclusões Apesar do esforço da comunidade científica em encontrarmedicamentos realmente eficazes no tratamento da migrânea, dado o grande número de medicamentos testados para este fim, ainda dispomos de poucas opções terapêuticas.

https://doi.org/10.1055/s-0042-1755320

Consensus of the Brazilian Headache Society (SBCe) for the Prophylactic Treatment of Episodic Migraine: part I
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Melhado, Eliana Meire

; Santos, Paulo Sergio Faro

; Kaup, Alexandre Ottoni

; Costa, Aline Turbino Neves Martins da

; Roesler, Célia Aparecida de Paula

; Piovesan, Élcio Juliato

; Sarmento, Elder Machado

; Theotonio, Giselle Oliveira Martins

; Campos, Henrique Carneiro de

; Fortini, Ida

; Souza, Jano Alves de

; Maciel Júnior, Jayme Antunes

; Segundo, João Batista Alves

; Carvalho, João José Freitas de

; Speziali, José Geraldo

; Calia, Leandro Cortoni

; Barea, Liselotte Menke

; Queiroz, Luiz Paulo

; Souza, Marcio Nattan Portes

; Figueiredo, Marcos Ravi Cerqueira Ferreira

; Costa, Maria Eduarda Nobre de Magalhães

; Peres, Mário Fernando Prieto

; Jurno, Mauro Eduardo

; Peixoto, Patrícia Machado

; Kowacs, Pedro André

; Rocha-Filho, Pedro Augusto Sampaio

; Moreira Filho, Pedro Ferreira

; Silva-Neto, Raimundo Pereira

; Fragoso, Yara Dadalti

Arquivos de Neuro-Psiquiatria

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aug 2022, Volume 80 N. 8 Pages 845 - 861

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The Brazilian Headache Society (Sociedade Brasileira de Cefaleia, SBCe, in Portuguese) nominated a Committee of Authors with the aim of establishing a consensus with recommendations regarding prophylactic treatment for episodic migraine based on articles published in the worldwide literature, as well as personal experience. Migraine affects 1 billion people around the world and more than 30 million Brazilians. In addition, it is an underdiagnosed and undertreated disorder. It is well known within the medical community of neurologists, and especially among headache specialists, that there is a need to disseminate knowledge about prophylactic treatment for migraine. For this purpose, together with the need for drug updates and to expand knowledge of the disease itself (frequency, intensity, duration, impact and perhaps the progression of migraine), this Consensus was developed, following a full online methodology, by 12 groups who reviewed and wrote about the pharmacological categories of the drugs used and, at the end of the process, met to read and establish conclusions for this document. The drug classes studied were: anticonvulsants, tricyclic antidepressants, monoclonal anti-calcitonin gene-related peptide (anti-CGRP) antibodies, beta-blockers, antihypertensives, calcium channel inhibitors, other antidepressants (selective serotonin reuptake inhibitors, SSRIs, and dual-action antidepressants), other drugs, and polytherapy. Hormonal treatment and anti-inflammatories and triptans in minimum prophylaxis schemes (miniprophylaxis) will be covered in a specific chapter. The drug classes studied for part I of the Consensus were: anticonvulsants, tricyclic antidepressants, monoclonal anti-CGRP antibodies, and beta-blockers.

Resumo A Sociedade Brasileira de Cefaleia (SBCe) nomeou um Comitê de Autores com o objetivo de estabelecer um consenso com recomendações sobre o tratamento profilático da enxaqueca episódica com base em artigos da literatura mundial e da experiência pessoal. A enxaqueca é um distúrbio subdiagnosticado e subtratado que acomete um bilhão de pessoas no mundo e mais de 30 milhões de brasileiros. É conhecido na comunidade médica de neurologistas e, sobretudo, dos especialistas em cefaleia, a necessidade de se divulgar o conhecimento sobre o tratamento profilático da enxaqueca. Com esta finalidade, aliada às necessidades de atualizações de drogas e de se aumentar o conhecimento sobre a doença em si (frequência, intensidade, duração, impacto e talvez a progressão da enxaqueca), foi elaborado este Consenso, com metodologia totalmente on-line, por 12 grupos que revisaram e escreveram sobre as categorias farmacológicas das drogas e, ao final, reuniram-se para a leitura e conclusão do documento. As classes de drogas estudadas para este Consenso foram: anticonvulsivantes, antidepressivos tricíclicos, anticorpos monoclonais do antipeptídeo relacionado ao gene da calcitonina (peptídeo relacionado ao gene da calcitonina — anti-CGRP), betabloqueadores, anti-hipertensivos, inibidores dos canais de cálcio, outros antidepressivos (inibidores seletivos de recaptação de serotonina, ISRSs, e antidepressivos de ação dual), outras drogas, e politerapia. O tratamento hormonal, bem como anti-inflamatórios e triptanas em esquema de profilaxia mínima (miniprofilaxia), será abordado em um capítulo próprio. As classes de drogas estudadas na parte I do Consenso foram: anticonvulsivantes, antidepressivos tricíclicos, anticorpos monoclonais anti-CGRP, e betabloqueadores.

https://doi.org/10.1055/s-0042-1756441

Pull Production Implementation: An Action Research Study
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Vasconcellos, Luis Henrique Rigato

; Sampaio, Mauro

; Fonseca, Henrique

Revista de Administração Contemporânea

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2022, Volume 26 N. 6 elocation e210151

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Contexto: existe pouca evidência empírica da relação entre a implementação efetiva de técnicas lean e o seu real efeito na performance da cadeia produtiva. Objetivo: o objetivo deste artigo foi descrever o processo de implementação da lógica de produção puxada na cadeia de suprimentos, relatando a evolução histórica dos indicadores associados à mudança, como os níveis de estoque e os lead times ao longo de 23 meses de intervenção. Métodos: foi conduzido um projeto de pesquisa-ação descrevendo os passos da intervenção na cadeia entre os anos de 2017, 2018 e 2019, dividida em fases: o planejamento, a coleta de dados, a implementação da ação, a análise e a avaliação dos resultados. Resultados: a principal contribuição foi demonstrar que a mudança de produção empurrada para puxada na pesquisa impactou positivamente os indicadores de lead time, estoque e rotinas de planejamento. Houve a redução de mais de 30% para os níveis de inventários e cerca de 40% para os lead times, além do aumento da assertividade da previsão de vendas. Conclusão: o artigo pode ser uma possível referência para organizações que queiram promover alterações semelhantes em suas cadeias de suprimentos e alterar de maneira significativa a rotina de planejamento de seus fornecedores e distribuidores através da implementação da lógica puxada.

ABSTRACT Context: there is little empirical evidence of the relationship between the implementation of lean techniques (such as the pull system) and their real effect on supply chain performance. Objective: the purpose of this paper is to describe the process of implementing the pull production logic in the supply chain, reporting the historical evolution of indicators, such as inventory levels and lead times over 23 months of intervention. Methods: an action research project was carried out describing chain intervention steps in 2017-2019, divided into phases as follows: planning, data collection, implementation of the action, analysis and evaluation of the results. Results: the main contribution was to demonstrate that the production shift from push to pull had a positive impact on lead time, inventory, and planning routines indicators. Inventory levels were reduced by more than 30% and lead times were down approximately 40%. In addition, sales forecast assertiveness increased. Conclusion: this paper may provide a reference for organizations that want to make similar changes in their supply chains and significantly change the planning routine of their suppliers and distributors by implementing the pull logic.

https://doi.org/10.1590/1982-7849rac2022210151.en

Avaliação do ciclo de vida de lajes pré-moldadas treliçadas com adição de resíduos de borracha de pneu
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Sampaio, Daniel Oliveira de Azevedo

; Rufato, Thássia Dias Zanardo

; Assunção, Camila Cassola

; Tashima, Mauro Mitsuuchi

; Akasaki, Jorge Luís

Matéria (Rio de Janeiro)

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2022, Volume 27 N. 2 elocation e13213

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The Life Cycle Assessment (LCA) has gained notoriety as a tool for analyzing the environmental impacts of products and services, standing out for analyzing all processes involved in production, from raw material extraction to final disposal, and enabling the preference for more environmentally sustainable materials and processes. This project evaluated and compared the environmental impacts of two concrete traces used in lattice precast slabs, one using tire rubber residue to partially replace sand, while the other uses only sand. The method used for the Life Cycle Impact Assessment (LCIA) phase was CML2001, and a sensitivity analysis was performed using the ReCiPe method. The slab made of concrete containing tire rubber residue generated, on average, 5% more emissions in all impact categories analyzed, being the production of CP II Z 32 cement the most critical process. The change in the LCIA method did not alter the conclusions obtained for the assessed impact categories.

RESUMO A Avaliação do Ciclo de Vida (ACV) vem ganhando notoriedade como ferramenta de análise dos impactos ambientais de produtos e serviços, destacando-se por analisar todos os processos envolvidos na produção, desde a extração da matéria-prima até o descarte final, e possibilitando a preferência por materiais e processos mais sustentáveis do ponto de vista ambiental. Esse trabalho avaliou e comparou os impactos ambientais de dois traços de concreto utilizados em lajes pré-moldadas treliçadas, sendo que um utiliza resíduo de borracha de pneu em substituição parcial da areia, enquanto o outro utiliza somente areia. O método utilizado para a fase de Avaliação de Impacto do Ciclo de Vida (AICV) foi o CML2001, e uma análise de sensibilidade foi realizada, utilizando o método ReCiPe. A laje elaborada com concreto contendo resíduo de borracha de pneu gerou, em média, 5% a mais de emissões em todas as categorias de impacto analisadas, sendo a produção de cimento do tipo CP II Z 32 o processo mais crítico. A mudança de método de AICV não alterou, para as categorias de impacto avaliadas, as conclusões obtidas.

https://doi.org/10.1590/s1517-707620220002.1313

Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: sífilis adquirida
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Freitas, Francisca Lidiane Sampaio

; Benzaken, Adele Schwartz

; Passos, Mauro Romero Leal de

; Coelho, Ivo Castelo Branco

; Miranda, Angélica Espinosa

Epidemiologia e Serviços de Saúde

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2021, Volume 30 N. spe1 elocation e2020616

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O Protocolo Clínico e Diretrizes Terapêuticas para Atenção Integral às Pessoas com Infecções Sexualmente Transmissíveis, publicado pelo Ministério da Saúde do Brasil em 2020, contempla a atualização sobre sífilis adquirida. O documento apresenta a utilização de testes rápidos, a segurança e a eficácia da administração da benzilpenicilina benzatina, o seguimento dos casos, o manejo clínico e laboratorial da neurossífilis, a abordagem de parcerias sexuais, a assistência e o acompanhamento de gestantes diagnosticadas e as especificidades da coinfecção sífilis e HIV, além de uma síntese sobre a notificação dos casos. É necessário capacitar gestores e profissionais de saúde de forma contínua, com vistas à integração entre assistência e vigilância, ao fortalecimento de ações efetivas de controle da sífilis, à abrangência da busca de parcerias sexuais e ao amplo acesso de populações mais vulneráveis aos serviços de saúde.

Abstract The Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections, published by the Ministry of Health of Brazil in 2020, includes the update on acquired syphilis. The document comprises rapid tests use, safety and efficacy of the administration of benzathine benzylpenicillin, follow-up of cases, clinical and laboratory management of neurosyphilis, approach to sexual partnerships, assistance and monitoring of diagnosed pregnant women, and specificities of syphilis and HIV co-infection, as well as a summary of the notification of cases. It is necessary to train health managers and professionals on a continuous basis, with a view to integrating care and surveillance, strengthening effective syphilis control actions, increasing the search for sexual partnerships, and expanding the access of the most vulnerable populations to health services.

Resumen El Protocolo Clínico y Directrices Terapéuticas para Atención Integral a las Personas con Infecciones de Transmisión Sexual, publicado por el Ministerio de Salud de Brasil en 2020, incluye la actualización sobre la sífilis adquirida. El documento comprende las pruebas rápidas, la seguridad y eficacia de la administración de bencilpenicilina benzatina, el seguimiento de casos, el manejo clínico y de laboratorio de la neurosífilis, el enfoque de las parejas sexuales, la asistencia y seguimiento de embarazadas diagnosticadas y las especificidades de la coinfección sífilis y VIH, bien como un resumen de la notificación de casos. Es necesario capacitar a los gestores y profesionales de la salud de manera continua, con miras a integrar la atención y la vigilancia, a fortalecer las acciones efectivas de control de la sífilis, a expandir la búsqueda de las parejas sexuales y a ampliar el acceso de las poblaciones más vulnerables a los servicios de salud.

https://doi.org/10.1590/s1679-4974202100004.esp1 4692 downloads

Políticas públicas em infecções sexualmente transmissíveis no Brasil
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Miranda, Angélica Espinosa

; Freitas, Francisca Lidiane Sampaio

; Passos, Mauro Romero Leal de

; Lopez, Miguel Angel Aragón

; Pereira, Gerson Fernando Mendes

Epidemiologia e Serviços de Saúde

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2021, Volume 30 N. spe1 elocation e2020611

Abstract: Pt Es | Text: Pt Es | PDF: Pt | PDF: Es

https://doi.org/10.1590/s1679-4974202100019.esp1 1980 downloads

10.

Brazilian recommendations for the use of nonsteroidal anti-inflammatory drugs in patients with axial spondyloarthritis
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Lage, Ricardo da Cruz

; Marques, Claudia Diniz Lopes

; Oliveira, Thauana Luiza

; Resende, Gustavo Gomes

; Kohem, Charles Lubianca

; Saad, Carla Gonçalves

; Ximenes, Antônio Carlos

; Gonçalves, Célio Roberto

; Bianchi, Washington Alves

; Meirelles, Eduardo de Souza

; Keiserman, Mauro Waldemar

; Chiereghin, Adriano

; Campanholo, Cristiano Barbosa

; Lyrio, André Marun

; Schainberg, Cláudia Goldenstein

; Pieruccetti, Lenise Brandao

; Yazbek, Michel Alexandre

; Palominos, Penelope Esther

; Goncalves, Rafaela Silva Guimarães

; Assad, Rodrigo Luppino

; Bonfiglioli, Rubens

; Lima, Sônia Maria Alvarenga Anti Loduca

; Carneiro, Sueli

; Azevedo, Valderílio Feijó

; Albuquerque, Cleandro Pires

; Bernardo, Wanderley Marques

; Sampaio-Barros, Percival Degrava

; Pinheiro, Marcelo de Medeiros

Advances in Rheumatology

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2021, Volume 61 elocation 4

Abstract: En | Text: En | PDF: En

Abstract Spondyloarthritis (SpA) is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. Over some decades, nonsteroidal anti-inflammatory drugs (NSAIDs) have been the basis for the pharmacological treatment of patients with axial spondyloarthritis (axSpA). However, the emergence of the immunobiologic agents brought up the discussion about the role of NSAIDs in the management of these patients. The objective of this guideline is to provide recommendations for the use of NSAIDs for the treatment of axSpA. A panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis of randomized clinical trials for 15 predefined questions. The Grading of Recommendations, Assessment, Development and Evaluation methodology to assess the quality of evidence and formulate recommendations were used, and at least 70% agreement of the voting panel was needed. Fourteen recommendations for the use of NSAIDs in the treatment of patients with axSpA were elaborated. The purpose of these recommendations is to support clinicians’ decision making, without taking out his/her autonomy when prescribing for an individual patient.

https://doi.org/10.1186/s42358-020-00160-6 505 downloads

11.

Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: sífilis adquirida
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Freitas, Francisca Lidiane Sampaio

; Benzaken, Adele Schwartz

; Passos, Mauro Romero Leal de

; Coelho, Ivo Castelo Branco

; Miranda, Angélica Espinosa

Epidemiologia e Serviços de Saúde

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2021, Volume 30 N. spe1 elocation e2020616

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/s1679-4974202100004.esp1

12.

Políticas públicas em infecções sexualmente transmissíveis no Brasil
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Miranda, Angélica Espinosa

; Freitas, Francisca Lidiane Sampaio

; Passos, Mauro Romero Leal de

; Lopez, Miguel Angel Aragón

; Pereira, Gerson Fernando Mendes

Epidemiologia e Serviços de Saúde

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2021, Volume 30 N. spe1 elocation e2020611

Abstract: Pt Es | Text: Pt Es | PDF: Pt | PDF: Es

https://doi.org/10.1590/s1679-4974202100019.esp1

13.

Brazilian Protocol for Sexually Transmitted Infections 2020: acquired syphilis
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Freitas, Francisca Lidiane Sampaio

; Benzaken, Adele Schwartz

; Passos, Mauro Romero Leal de

; Coelho, Ivo Castelo Branco

; Miranda, Angélica Espinosa

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 Suppl. 1 elocation e2020616

Abstract: En | Text: En | PDF: En

Abstract The Clinical Protocol and Therapeutic Guidelines for Comprehensive Care of People with Sexually Transmitted Infections, published by the Brazilian Ministry of Health in 2020, includes updates concerning acquired syphilis. The document comprises rapid test use, safety and efficacy of benzathine benzylpenicillin, case follow-up, neurosyphilis clinical and laboratory management, approaching sex partners, assistance and monitoring of diagnosed pregnant women, and syphilis and HIV co-infection specificities, as well as a case notification summary. Health managers and professionals must be continuously trained so as to integrate care and surveillance, to strengthen actions for efficient control of syphilis, to broaden the search for sex partners, and to expand access of most vulnerable populations to health services.

https://doi.org/10.1590/0037-8682-616-2020 390 downloads

14.

Public policies on sexually transmitted infections in Brazil
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Miranda, Angélica Espinosa

; Freitas, Francisca Lidiane Sampaio

; Passos, Mauro Romero Leal de

; Lopez, Miguel Angel Aragón

; Pereira, Gerson Fernando Mendes

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 Suppl. 1 elocation e2020611

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0037-8682-611-2020 260 downloads

15.

Brazilian Society of Rheumatology 2020 guidelines for psoriatic arthritis
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Carneiro, Sueli

; Palominos, Penelope Esther

; Anti, Sônia Maria Alvarenga

; Assad, Rodrigo Luppino

; Gonçalves, Rafaela Silva Guimarães

; Chiereghin, Adriano

; Lyrio, Andre Marun

; Ximenes, Antônio Carlos

; Saad, Carla Gonçalves

; Gonçalves, Célio Roberto

; Kohem, Charles Lubianca

; Marques, Cláudia Diniz Lopes

; Schainberg, Cláudia Goldenstein

; Meirelles, Eduardo de Souza

; Resende, Gustavo Gomes

; Pieruccetti, Lenise Brandao

; Keiserman, Mauro Waldemar

; Yazbek, Michel Alexandre

; Sampaio-Barros, Percival Degrava

; Lage, Ricardo da Cruz

; Bonfiglioli, Rubens

; Oliveira, Thauana Luíza

; Azevedo, Valderílio Feijó

; Bianchi, Washington Alves

; Bernardo, Wanderley Marques

; Simões, Ricardo dos Santos

; Pinheiro, Marcelo de Medeiros

; Campanholo, Cristiano Barbosa

Advances in Rheumatology

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2021, Volume 61 elocation 69

Abstract: En | Text: En | PDF: En

Abstract Psoriatic arthritis (PsA) is a chronic and systemic immune disease characterized by inflammation of peripheral and/ or axial joints and entheses in patients with psoriasis (PsO). Extra-articular and extracutaneous manifestations and numerous comorbidities can also be present. These recommendations replace the previous version published in May 2013. A systematic review of the literature retrieved 191 articles that were used to formulate 12 recommendations in response to 12 clinical questions, divided into 4 sections: diagnosis, non-pharmacological treatment, conventional drug therapy and biologic therapy. These guidelines provide evidence-based information on the clinical management for PsA patients. For each recommendation, the level of evidence (highest available), degree of strength (Oxford) and degree of expert agreement (interrater reliability) are reported.

https://doi.org/10.1186/s42358-021-00219-y

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