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1.
Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital
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Fink, Thais T.
; Marques, Heloisa H.S.
; Gualano, Bruno
; Lindoso, Livia
; Bain, Vera
; Astley, Camilla
; Martins, Fernanda
; Matheus, Denise
; Matsuo, Olivia M.
; Suguita, Priscila
; Trindade, Vitor
; Paula, Camila S.Y.
; Farhat, Sylvia C.L.
; Palmeira, Patricia
; Leal, Gabriela N.
; Suzuki, Lisa
; Odone Filho, Vicente
; Carneiro-Sampaio, Magda
; Duarte, Alberto José S.
; Antonangelo, Leila
; Batisttella, Linamara R.
; Polanczyk, Guilherme V.
; Pereira, Rosa Maria R.
; Carvalho, Carlos Roberto R.
; Buchpiguel, Carlos A.
; Latronico, Ana Claudia
; Seelaender, Marilia
; Silva, Clovis Artur
; Pereira, Maria Fernanda B.
; Sallum, Adriana M. E.
; Brentani, Alexandra V. M.
; Neto, Álvaro José S.
; Ihara, Amanda
; Santos, Andrea R.
; Canton, Ana Pinheiro M.
; Watanabe, Andreia
; Santos, Angélica C. dos
; Pastorino, Antonio C.
; Franco, Bernadette D. G. M.
; Caruzo, Bruna
; Ceneviva, Carina
; Martins, Carolina C. M. F.
; Prado, Danilo
; Abellan, Deipara M.
; Benatti, Fabiana B.
; Smaria, Fabiana
; Gonçalves, Fernanda T.
; Penteado, Fernando D.
; Castro, Gabriela S. F. de
; Gonçalves, Guilherme S.
; Roschel, Hamilton
; Disi, Ilana R.
; Marques, Isabela G.
; Castro, Inar A.
; Buscatti, Izabel M.
; Faiad, Jaline Z.
; Fiamoncini, Jarlei
; Rodrigues, Joaquim C.
; Carneiro, Jorge D. A.
; Paz, Jose A.
; Ferreira, Juliana C.
; Ferreira, Juliana C. O.
; Silva, Katia R.
; Bastos, Karina L. M.
; Kozu, Katia
; Cristofani, Lilian M.
; Souza, Lucas V. B.
; Campos, Lucia M. A.
; Silva Filho, Luiz Vicente R. F.
; Sapienza, Marcelo T.
; Lima, Marcos S.
; Garanito, Marlene P.
; Santos, Márcia F. A.
; Dorna, Mayra B.
; Aikawa, Nadia E.
; Litvinov, Nadia
; Sakita, Neusa K.
; Gaiolla, Paula V. V.
; Pasqualucci, Paula
; Toma, Ricardo K.
; Correa-Silva, Simone
; Sieczkowska, Sofia M.
; Imamura, Marta
; Forsait, Silvana
; Santos, Vera A.
; Zheng, Yingying
.
OBJECTIVES: To prospectively evaluate demographic, anthropometric and health-related quality of life (HRQoL) in pediatric patients with laboratory-confirmed coronavirus disease 2019 (COVID-19) METHODS: This was a longitudinal observational study of surviving pediatric post-COVID-19 patients (n=53) and pediatric subjects without laboratory-confirmed COVID-19 included as controls (n=52) was performed. RESULTS: The median duration between COVID-19 diagnosis (n=53) and follow-up was 4.4 months (0.8-10.7). Twenty-three of 53 (43%) patients reported at least one persistent symptom at the longitudinal follow-up visit and 12/53 (23%) had long COVID-19, with at least one symptom lasting for >12 weeks. The most frequently reported symptoms at the longitudinal follow-up visit were headache (19%), severe recurrent headache (9%), tiredness (9%), dyspnea (8%), and concentration difficulty (4%). At the longitudinal follow-up visit, the frequencies of anemia (11% versus 0%, p=0.030), lymphopenia (42% versus 18%, p=0.020), C-reactive protein level of >30 mg/L (35% versus 0%, p=0.0001), and D-dimer level of >1000 ng/mL (43% versus 6%, p=0.0004) significantly reduced compared with baseline values. Chest X-ray abnormalities (11% versus 2%, p=0.178) and cardiac alterations on echocardiogram (33% versus 22%, p=0.462) were similar at both visits. Comparison of characteristic data between patients with COVID-19 at the longitudinal follow-up visit and controls showed similar age (p=0.962), proportion of male sex (p=0.907), ethnicity (p=0.566), family minimum monthly wage (p=0.664), body mass index (p=0.601), and pediatric pre-existing chronic conditions (p=1.000). The Pediatric Quality of Live Inventory 4.0 scores, median physical score (69 [0-100] versus 81 [34-100], p=0.012), and school score (60 [15-100] versus 70 [15-95], p=0.028) were significantly lower in pediatric patients with COVID-19 at the longitudinal follow-up visit than in controls. CONCLUSIONS: Pediatric patients with COVID-19 showed a longitudinal impact on HRQoL parameters, particularly in physical/school domains, reinforcing the need for a prospective multidisciplinary approach for these patients. These data highlight the importance of closer monitoring of children and adolescents by the clinical team after COVID-19.
2.
ENVIRONMENTAL THERMAL COMFORT OF A REDUCED MODEL USING CROSS-LAMINATED TIMBER
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Sampaio, Carlos A. de P.
; Terezo, Rodrigo F.
; Motta, Guilherme
; Silva, Leonardo M. da C.
; Vassem Júnior, Ilson
.
ABSTRACT The challenges for the use of the cross-laminated timber (CLT) system in the Brazilian agricultural market are significant. This study evaluated the thermal performance of fiber cement tiles associated with a CLT non-conventional structure compared to those of ceramic, fiber cement and aluminum roof tiles based on following thermal comfort indexes (i.e., black globe humidity index (BGHI), radiant heat load (RHL) and specific enthalpy) using physical conventional models of reduced-scale rural facilities under summer conditions. The non-conventional CLT model comprised closing walls and a lining that form a self-supporting structure with few air inlets. This model presented reduced thermal comfort indexes compared to the other conventional roofs. Moreover, the CLT model has an average black globe temperature (Tbg) of 32.9 °C, which was lower at all times compared to those of the other roofs. In conclusion, the roof with fiber cement tiles associated with the CLT structure exhibited the best performance in terms of thermal comfort, followed by the ceramic, fiber cement, and aluminum tiles. The study results allow a better understanding of the opportunities for CLT usage.
3.
HYSTERESIS AND THERMAL INERTIA OF SPHERES OF ALTERNATIVE MATERIALS FOR BLACK GLOBE THERMOMETERS
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Sampaio, Carlos A. de P.
; Terezo, Rodrigo F.
; Vassem Júnior, Ilson
; Silva, Leonardo M. da C.
; Borges, Luiza K.
.
ABSTRACT This research was conducted with the objective of evaluating the thermal inertia and hysteresis of the following materials in a wind tunnel: hollow copper sphere with 150.0 mm diameter used as standard in globe thermometers, hollow brass sphere with 75.0 mm diameter, and two hollow plastic spheres with 115.5 and 69.7 mm diameter. The results showed that the thermal inertia and hysteresis for the hollow copper sphere were approximately 24 and 28 min, respectively; these values were bigger than those obtained for the other spheres, implying faster responses of these. While there were no statistical differences in the measurements conducted by globe thermometers which are used to indicate the black globe temperature with the different types of spheres mentioned above under indoor environment conditions, i.e., with no wind and solar radiation, the wind causes faster cooling in smaller spheres under outdoor environment conditions, which may denote erroneous interpretations of the measurements at those instants. It was concluded that it is possible to replace the hollow copper sphere of diameter 150 mm by other types of spheres to measure the black globe temperature. However, this requires knowledge of the response times of the spheres as well as corrections to be made in the measurements with respect to the globe thermometer standard.
4.
CHEMICALLY TREATED GLUED LAMINATED PARICÁ TIMBER (Schizolobium parahyba var. amazonicum)
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ABSTRACT In the production of glue-laminated timber (GLT), boards derived from planted forest wood with easy workability are glued on top of one another. The main objective of the present work was to evaluate the performance of paricá timber GLT beams (5 × 10 cm) on GLT. Three procedures were performed: (1) GLT beams (5 × 10 cm) were produced using natural lamellae without chemical preservatives; (2) the individual lamellae (2.5 × 5 cm) were chemically treated, and then glued together; and (3) the beams formed from the glued natural lamellae (5 × 10 cm) were treated chemically. The positions of lamellae on the beams were determined by their modulus of elasticity values (MOE), which were estimated by a non-destructive bending test with a three-point load. The analytical bends, determined by the homogenized section method, and the experimental bends, measured by the four-point bending test, were compared. The differences between the bends were statistically evaluated, and it was found that the experimental bend (21.65 mm) was less than the analytical bend (34.02 mm). There was no significant loss of shear strength or MOE. The axial strength of the chemically untreated beams (49.18 MPa) was significantly higher than that of the untreated beams fabricated from natural lamellae (40.48 MPa). The results indicate that the gluing of treated lamellae does not affect beam performance.
5.
SIMILITUDE AND THERMAL PERFORMANCE ON NON-CONVENTIONAL ROOFS
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Sampaio, Carlos A. de P.
; Terezo, Rodrigo F.
; Rosa, Talitha O.
; Burigo, Mariana C.
; Andrade, Leonardo de B.
.
ABSTRACT The objectives of this study were to evaluate the thermal comfort and the similitude between prototypes and reduced models, using non-conventional coverage with green roof and expanded clay aggregate, supported on wood frame structure. For this, were determined the Black Globe Temperature and Humidity Index (BGHI), the Human Discomfort Index (HDI), Effective Temperature (ET), Air Temperature (Tair) and Radiant Thermal Load (RTL), from March 2013 to December 2014. The results showed that there were no statistical differences to 5% significance in predicting heat indices between the prototypes and models. Observing all indexes simultaneously, it was observed that January was the month what led to the worst heat conditions, while June and July showed the worst cold conditions. It can be concluded that the use of reduced models is possible (1:2) compared to the prototype (1:1), with green roofs and expanded clay as covering element, for the prediction of thermal indexes, minimizing construction costs and use of spaces.
6.
Azole resistance in Candida spp. isolated from Catú Lake, Ceará, Brazil: an efflux-pump-mediated mechanism
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Brilhante, Raimunda S.N.
; Paiva, Manoel A.N.
; Sampaio, Célia M.S.
; Castelo-Branco, Débora S.C.M.
; Teixeira, Carlos E.C.
; Alencar, Lucas P. de
; Bandeira, Tereza J.P.G.
; Monteiro, André J.
; Cordeiro, Rossana A.
; Pereira-Neto, Waldemiro A.
; Sidrim, José J.C.
; Moreira, José L.B.
; Rocha, Marcos F.G.
.
Abstract Since, there is no study reporting the mechanism of azole resistance among yeasts isolated from aquatic environments; the present study aims to investigate the occurrence of antifungal resistance among yeasts isolated from an aquatic environment, and assess the efflux-pump activity of the azole-resistant strains to better understand the mechanism of resistance for this group of drugs. For this purpose, monthly water and sediment samples were collected from Catú Lake, Ceará, Brazil, from March 2011 to February 2012. The obtained yeasts were identified based on morphological and biochemical characteristics. Of the 46 isolates, 37 were Candida spp., 4 were Trichosporon asahii, 3 were Cryptococcus laurentii, 1 Rhodotorula mucilaginosa, and 1 was Kodamaea ohmeri. These isolates were subjected to broth microdilution assay with amphotericin B, itraconazole, and fluconazole, according to the methodology standardized by the Clinical and Laboratory Standards Institute (CLSI). The minimum inhibitory concentrations (MICs) of amphotericin B, itraconazole, and fluconazole were 0.03125–2 µg/mL, 0.0625 to ≥16 µg/mL, and 0.5 to ≥64 µg/mL, respectively, and 13 resistant azole-resistant Candida isolates were detected. A reduction in the azole MICs leading to the phenotypical reversal of the azole resistance was observed upon addition of efflux-pump inhibitors. These findings suggest that the azole resistance among environmental Candida spp. is most likely associated with the overexpression of efflux-pumps.
https://doi.org/10.1016/j.bjm.2015.11.008
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7.
Qualidade de vida nas espondiloartrites: análise de uma grande coorte brasileira
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Ribeiro, Sandra L.E.
; Albuquerque, Elisa N.
; Bortoluzzo, Adriana B.
; Gonçalves, Célio R.
; Silva, José Antonio Braga da
; Ximenes, Antonio Carlos
; Bértolo, Manoel B.
; Keiserman, Mauro
; Menin, Rita
; Skare, Thelma L.
; Carneiro, Sueli
; Azevedo, Valderílio F.
; Vieira, Walber P.
; Bianchi, Washington A.
; Bonfiglioli, Rubens
; Campanholo, Cristiano
; Carvalho, Hellen M.S.
; Costa, Izaias P.
; Duarte, Angela L.B. Pinto
; Kohem, Charles L.
; Leite, Nocy H.
; Lima, Sonia A.L.
; Meirelles, Eduardo S.
; Pereira, Ivânio A.
; Pinheiro, Marcelo M.
; Polito, Elizandra
; Resende, Gustavo G.
; Rocha, Francisco Airton C.
; Santiago, Mittermayer B.
; Sauma, Maria de Fátima L.C.
; Valim, Valéria
; Sampaio-Barros, Percival D.
.
Resumo Objetivo: Analisar as variáveis demográficas e clínicas associadas à diminuição da qualidade de vida em uma grande coorte brasileira de pacientes com espondiloartrite (EpA). Métodos: Foi aplicado um protocolo de pesquisa único a 1.465 pacientes brasileiros classificados como tendo EpA de acordo com os critérios do European Spondyloarthropaties Study Group (ESSG), atendidos em 29 centros de referência em reumatologia do Brasil. Foram registradas as variáveis clínicas e demográficas. A qualidade de vida foi analisada por meio do questionário Ankylosing Spondylitis Quality of Life (ASQoL). Resultados: A pontuação média do ASQoL foi de 7,74 (+ 5,39). Ao analisar doenças específicas no grupo de EpA, as pontuações do ASQoL não apresentaram diferença estatisticamente significativa. Os dados demográficos mostraram piores escores de ASQoL associados ao gênero feminino (p = 0,014) e etnia negra (p < 0,001). Quanto aos sintomas clínicos, a dor na região glútea (p = 0,032), a dor cervical (p < 0,001) e a dor no quadril (p = 0,001), estiveram estatisticamente associadas a piores escores no ASQoL. O uso contínuo de fármacos anti-inflamatórios não esteroides (p < 0,001) e agentes biológicos (p = 0,044) esteve associado a escores mais elevados de ASQoL, enquanto outros medicamentos não interferiram nos escores do ASQoL. Conclusão: Nesta grande série de pacientes com EpA, o sexo feminino e a etnia negra, bem como sintomas predominantemente axiais, estiveram associados a uma qualidade de vida reduzida.
Abstract Objective: To analyze quality of life and demographic and clinical variables associated to its impairment in a large Brazilian cohort of patients with spondyloarthritis (SpA). Methods: A common protocol of investigation was applied to 1465 Brazilian patients classified as SpA according to the European Spondyloarthropaties Study Group (ESSG) criteria, attended at 29 reference centers for Rheumatology in Brazil. Clinical and demographic variables were recorded. Quality of life was analyzed through the Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire. Results: The mean ASQoL score was 7.74 (± 5.39). When analyzing the specific diseases in the SpA group, the ASQoL scores did not present statistical significance. Demographic data showed worse scores of ASQoL associated with female gender (p = 0.014) and African-Brazilian ethnicity (p < 0.001). Regarding clinical symptoms, buttock pain (p = 0.032), cervical pain (p < 0.001) and hip pain (p = 0.001), were statistically associated with worse scores of ASQoL. Continuous use of nonsteroidal anti-inflammatory drugs (p < 0.001) and biologic agents (p = 0.044) were associated with higher scores of ASQoL, while the other medications did not interfere with the ASQoL scores. Conclusion: In this large series of patients with SpA, female gender and African-Brazilian ethnicity, as well as predominant axial symptoms, were associated with impaired quality of life.
https://doi.org/10.1016/j.rbr.2015.03.003
3358 downloads
8.
Avaliação do desempenho do BASDAI (Bath Ankylosing Spondylitis Disease Activity Index) numa coorte brasileira de 1.492 pacientes com espondiloartrites: dados do Registro Brasileiro de Espondiloartrites (RBE)
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Costa, Izaias Pereira da
; Bortoluzzo, Adriana B.
; Gonçalves, Célio R.
; Silva, José Antonio Braga da
; Ximenes, Antonio Carlos
; Bértolo, Manoel B.
; Ribeiro, Sandra L.E.
; Keiserman, Mauro
; Menin, Rita
; Skare, Thelma L.
; Carneiro, Sueli
; Azevedo, Valderílio F.
; Vieira, Walber P.
; Albuquerque, Elisa N.
; Bianchi, Washington A.
; Bonfiglioli, Rubens
; Campanholo, Cristiano
; Carvalho, Hellen M.S.
; Duarte, Angela L.B. Pinto
; Kohem, Charles L.
; Leite, Nocy H.
; Lima, Sonia A.L.
; Meirelles, Eduardo S.
; Pereira, Ivânio A.
; Pinheiro, Marcelo M.
; Polito, Elizandra
; Resende, Gustavo G.
; Rocha, Francisco Airton C.
; Santiago, Mittermayer B.
; Sauma, Maria de Fátima L.C.
; Valim, Valéria
; Sampaio-Barros, Percival D.
.
Objetivo Avaliar os resultados da aplicação do Índice de Atividade de Doença da Espondilite Anquilosante de Bath (BASDAI) numa série de pacientes brasileiros com EpA e estabelecer suas correlações com as variáveis específicas do grupo. Métodos Um protocolo comum de investigação foi prospectivamente aplicado em 1.492 pacientes brasileiros classificados como EpA pelos critérios do Grupo Europeu de Estudo das Espondiloartropatias (ESSG), acompanhados em 29 centros de referência em reumatologia no Brasil. Variáveis clínicas, demográficas e índices de doença foram colhidos. Os valores totais do BASDAI foram comparados com a presença das diferentes variáveis. Resultados O valor médio do BASDAI foi de 4,20 ± 2,38. Os escores médios do BASDAI foram mais elevados nos pacientes com forma clínica combinada, comparado às formas axiais e periféricas isoladas, nos pacientes do sexo feminino e nos sedentários. Com relação ao componente axial, valores mais altos do BASDAI estiveram significativamente associados à lombalgia inflamatória, à dor alternante em nádegas, à dor cervical e ao acometimento de coxofemorais. Houve associação estatística entre os valores do BASDAI e o comprometimento periférico, relacionado ao número de articulações inflamadas, tanto dos membros inferiores quanto dos membros superiores, e às entesites. A positividade do HLA-B27 e a presença de manifestações extra-articulares não estiveram correlacionadas com os valores médios do BASDAI. Valores mais baixos do BASDAI estiveram associados ao uso de agentes biológicos (p < 0,001). Conclusão Nesta série heterogênea de pacientes brasileiros com EpA, o BASDAI conseguiu demonstrar “atividade de doença” tanto nos pacientes com acometimento axial quanto naqueles com envolvimento periférico.
Objective To analyze the results of the application of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in a large series of Brazilian patients with the diagnosis of SpA and establish its correlations with specific variables into the group. Methods A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyoarthropathies Study Group (ESSG), attended at 29 referral centers of Rheumatology in Brazil. Clinical and demographic variables, and disease indices (BASDAI, Basfi, Basri, Mases, ASQol) were applied. The total values of BASDAI were compared to the presence of the different variables. Results The mean score of BASDAI was 4.20 ± 2.38. The mean scores of BASDAI were higher in patients with the combined (axial + peripheral + entheseal) (4.54 ± 2.38) clinical presentation, compared to the pure axial (3.78 ± 2.27) or pure peripheral (4.00 ± 2.38) clinical presentations (P < 0.001). BASDAI also presented higher scores associated with the female gender (P < 0.001) and patients who did not practice exercises (P < 0.001). Regarding the axial component, higher values of BASDAI were significantly associated with inflammatory low back pain (P < 0.049), alternating buttock pain (P < 0.001), cervical pain (P < 0.001) and hip involvement (P < 0.001). There was also statistical association between BASDAI scores and the peripheral involvement, related to the lower (P = 0.004) and upper limbs (P = 0.025). The presence of enthesitis was also associated to higher scores of BASDAI (P = 0.040). Positive HLA-B27 and the presence of cutaneous psoriasis, inflammatory bowel disease, uveitis and urethritis were not correlated with the mean scores of BASDAI. Lower scores of BASDAI were associated with the use of biologic agents (P < 0.001). Conclusion In this heterogeneous Brazilian series of SpA patients, BASDAI was able to demonstrate “disease activity” in patients with axial as well as peripheral disease.
https://doi.org/10.1016/j.rbr.2014.05.005
12259 downloads
9.
Growing knowledge: an overview of Seed Plant diversity in Brazil
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Zappi, Daniela C.
; Filardi, Fabiana L. Ranzato
; Leitman, Paula
; Souza, Vinícius C.
; Walter, Bruno M.T.
; Pirani, José R.
; Morim, Marli P.
; Queiroz, Luciano P.
; Cavalcanti, Taciana B.
; Mansano, Vidal F.
; Forzza, Rafaela C.
; Abreu, Maria C.
; Acevedo-Rodríguez, Pedro
; Agra, Maria F.
; Almeida Jr., Eduardo B.
; Almeida, Gracineide S.S.
; Almeida, Rafael F.
; Alves, Flávio M.
; Alves, Marccus
; Alves-Araujo, Anderson
; Amaral, Maria C.E.
; Amorim, André M.
; Amorim, Bruno
; Andrade, Ivanilza M.
; Andreata, Regina H.P.
; Andrino, Caroline O.
; Anunciação, Elisete A.
; Aona, Lidyanne Y.S.
; Aranguren, Yani
; Aranha Filho, João L.M.
; Araújo, Andrea O.
; Araújo, Ariclenes A.M.
; Araújo, Diogo
; Arbo, María M.
; Assis, Leandro
; Assis, Marta C.
; Assunção, Vivian A.
; Athiê-Souza, Sarah M.
; Azevedo, Cecilia O.
; Baitello, João B.
; Barberena, Felipe F.V.A.
; Barbosa, Maria R.V.
; Barros, Fábio
; Barros, Lucas A.V.
; Barros, Michel J.F.
; Baumgratz, José F.A.
; Bernacci, Luis C.
; Berry, Paul E.
; Bigio, Narcísio C.
; Biral, Leonardo
; Bittrich, Volker
; Borges, Rafael A.X.
; Bortoluzzi, Roseli L.C.
; Bove, Cláudia P.
; Bovini, Massimo G.
; Braga, João M.A.
; Braz, Denise M.
; Bringel Jr., João B.A.
; Bruniera, Carla P.
; Buturi, Camila V.
; Cabral, Elza
; Cabral, Fernanda N.
; Caddah, Mayara K.
; Caires, Claudenir S.
; Calazans, Luana S.B.
; Calió, Maria F.
; Camargo, Rodrigo A.
; Campbell, Lisa
; Canto-Dorow, Thais S.
; Carauta, Jorge P.P.
; Cardiel, José M.
; Cardoso, Domingos B.O.S.
; Cardoso, Leandro J.T.
; Carneiro, Camila R.
; Carneiro, Cláudia E.
; Carneiro-Torres, Daniela S.
; Carrijo, Tatiana T.
; Caruzo, Maria B.R.
; Carvalho, Maria L.S.
; Carvalho-Silva, Micheline
; Castello, Ana C.D.
; Cavalheiro, Larissa
; Cervi, Armando C.
; Chacon, Roberta G.
; Chautems, Alain
; Chiavegatto, Berenice
; Chukr, Nádia S.
; Coelho, Alexa A.O.P.
; Coelho, Marcus A.N.
; Coelho, Rubens L.G.
; Cordeiro, Inês
; Cordula, Elizabeth
; Cornejo, Xavier
; Côrtes, Ana L.A.
; Costa, Andrea F.
; Costa, Fabiane N.
; Costa, Jorge A.S.
; Costa, Leila C.
; Costa-e-Silva, Maria B.
; Costa-Lima, James L.
; Cota, Maria R.C.
; Couto, Ricardo S.
; Daly, Douglas C.
; De Stefano, Rodrigo D.
; De Toni, Karen
; Dematteis, Massimiliano
; Dettke, Greta A.
; Di Maio, Fernando R.
; Dórea, Marcos C.
; Duarte, Marília C.
; Dutilh, Julie H.A.
; Dutra, Valquíria F.
; Echternacht, Lívia
; Eggers, Lilian
; Esteves, Gerleni
; Ezcurra, Cecilia
; Falcão Junior, Marcus J.A.
; Feres, Fabíola
; Fernandes, José M.
; Ferreira, D.M.C.
; Ferreira, Fabrício M.
; Ferreira, Gabriel E.
; Ferreira, Priscila P.A.
; Ferreira, Silvana C.
; Ferrucci, Maria S.
; Fiaschi, Pedro
; Filgueiras, Tarciso S.
; Firens, Marcela
; Flores, Andreia S.
; Forero, Enrique
; Forster, Wellington
; Fortuna-Perez, Ana P.
; Fortunato, Reneé H.
; Fraga, Cléudio N.
; França, Flávio
; Francener, Augusto
; Freitas, Joelcio
; Freitas, Maria F.
; Fritsch, Peter W.
; Furtado, Samyra G.
; Gaglioti, André L.
; Garcia, Flávia C.P.
; Germano Filho, Pedro
; Giacomin, Leandro
; Gil, André S.B.
; Giulietti, Ana M.
; A.P.Godoy, Silvana
; Goldenberg, Renato
; Gomes da Costa, Géssica A.
; Gomes, Mário
; Gomes-Klein, Vera L.
; Gonçalves, Eduardo Gomes
; Graham, Shirley
; Groppo, Milton
; Guedes, Juliana S.
; Guimarães, Leonardo R.S.
; Guimarães, Paulo J.F.
; Guimarães, Elsie F.
; Gutierrez, Raul
; Harley, Raymond
; Hassemer, Gustavo
; Hattori, Eric K.O.
; Hefler, Sonia M.
; Heiden, Gustavo
; Henderson, Andrew
; Hensold, Nancy
; Hiepko, Paul
; Holanda, Ana S.S.
; Iganci, João R.V.
; Imig, Daniela C.
; Indriunas, Alexandre
; Jacques, Eliane L.
; Jardim, Jomar G.
; Kamer, Hiltje M.
; Kameyama, Cíntia
; Kinoshita, Luiza S.
; Kirizawa, Mizué
; Klitgaard, Bente B.
; Koch, Ingrid
; Koschnitzke, Cristiana
; Krauss, Nathália P.
; Kriebel, Ricardo
; Kuntz, Juliana
; Larocca, João
; Leal, Eduardo S.
; Lewis, Gwilym P.
; Lima, Carla T.
; Lima, Haroldo C.
; Lima, Itamar B.
; Lima, Laíce F.G.
; Lima, Laura C.P.
; Lima, Leticia R.
; Lima, Luís F.P.
; Lima, Rita B.
; Lírio, Elton J.
; Liro, Renata M.
; Lleras, Eduardo
; Lobão, Adriana
; Loeuille, Benoit
; Lohmann, Lúcia G.
; Loiola, Maria I.B.
; Lombardi, Julio A.
; Longhi-Wagner, Hilda M.
; Lopes, Rosana C.
; Lorencini, Tiago S.
; Louzada, Rafael B.
; Lovo, Juliana
; Lozano, Eduardo D.
; Lucas, Eve
; Ludtke, Raquel
; Luz, Christian L.
; Maas, Paul
; Machado, Anderson F.P.
; Macias, Leila
; Maciel, Jefferson R.
; Magenta, Mara A.G.
; Mamede, Maria C.H.
; Manoel, Evelin A.
; Marchioretto, Maria S.
; Marques, Juliana S.
; Marquete, Nilda
; Marquete, Ronaldo
; Martinelli, Gustavo
; Martins da Silva, Regina C.V.
; Martins, Ângela B.
; Martins, Erika R.
; Martins, Márcio L.L.
; Martins, Milena V.
; Martins, Renata C.
; Matias, Ligia Q.
; Maya-L., Carlos A.
; Mayo, Simon
; Mazine, Fiorella
; Medeiros, Debora
; Medeiros, Erika S.
; Medeiros, Herison
; Medeiros, João D.
; Meireles, José E.
; Mello-Silva, Renato
; Melo, Aline
; Melo, André L.
; Melo, Efigênia
; Melo, José I.M.
; Menezes, Cristine G.
; Menini Neto, Luiz
; Mentz, Lilian A.
; Mezzonato, A.C.
; Michelangeli, Fabián A.
; Milward-de-Azevedo, Michaele A.
; Miotto, Silvia T.S.
; Miranda, Vitor F.O.
; Mondin, Cláudio A.
; Monge, Marcelo
; Monteiro, Daniele
; Monteiro, Raquel F.
; Moraes, Marta D.
; Moraes, Pedro L.R.
; Mori, Scott A.
; Mota, Aline C.
; Mota, Nara F.O.
; Moura, Tania M.
; Mulgura, Maria
; Nakajima, Jimi N.
; Nardy, Camila
; Nascimento Júnior, José E.
; Noblick, Larry
; Nunes, Teonildes S.
; O'Leary, Nataly
; Oliveira, Arline S.
; Oliveira, Caetano T.
; Oliveira, Juliana A.
; Oliveira, Luciana S.D.
; Oliveira, Maria L.A.A.
; Oliveira, Regina C.
; Oliveira, Renata S.
; Oliveira, Reyjane P.
; Paixão-Souza, Bruno
; Parra, Lara R.
; Pasini, Eduardo
; Pastore, José F.B.
; Pastore, Mayara
; Paula-Souza, Juliana
; Pederneiras, Leandro C.
; Peixoto, Ariane L.
; Pelissari, Gisela
; Pellegrini, Marco O.O.
; Pennington, Toby
; Perdiz, Ricardo O.
; Pereira, Anna C.M.
; Pereira, Maria S.
; Pereira, Rodrigo A.S.
; Pessoa, Clenia
; Pessoa, Edlley M.
; Pessoa, Maria C.R.
; Pinto, Luiz J.S.
; Pinto, Rafael B.
; Pontes, Tiago A.
; Prance, Ghillean T.
; Proença, Carolyn
; Profice, Sheila R.
; Pscheidt, Allan C.
; Queiroz, George A.
; Queiroz, Rubens T.
; Quinet, Alexandre
; Rainer, Heimo
; Ramos, Eliana
; Rando, Juliana G.
; Rapini, Alessandro
; Reginato, Marcelo
; Reis, Ilka P.
; Reis, Priscila A.
; Ribeiro, André R.O.
; Ribeiro, José E.L.S.
; Riina, Ricarda
; Ritter, Mara R.
; Rivadavia, Fernando
; Rocha, Antônio E.S.
; Rocha, Maria J.R.
; Rodrigues, Izabella M.C.
; Rodrigues, Karina F.
; Rodrigues, Rodrigo S.
; Rodrigues, Rodrigo S.
; Rodrigues, Vinícius T.
; Rodrigues, William
; Romaniuc Neto, Sérgio
; Romão, Gerson O.
; Romero, Rosana
; Roque, Nádia
; Rosa, Patrícia
; Rossi, Lúcia
; Sá, Cyl F.C.
; Saavedra, Mariana M.
; Saka, Mariana
; Sakuragui, Cássia M.
; Salas, Roberto M.
; Sales, Margareth F.
; Salimena, Fatima R.G.
; Sampaio, Daniela
; Sancho, Gisela
; Sano, Paulo T.
; Santos, Alessandra
; Santos, Élide P.
; Santos, Juliana S.
; Santos, Marianna R.
; Santos-Gonçalves, Ana P.
; Santos-Silva, Fernanda
; São-Mateus, Wallace
; Saraiva, Deisy P.
; Saridakis, Dennis P.
; Sartori, Ângela L.B.
; Scalon, Viviane R.
; Schneider, Ângelo
; Sebastiani, Renata
; Secco, Ricardo S.
; Senna, Luisa
; Senna-Valle, Luci
; Shirasuna, Regina T.
; Silva Filho, Pedro J.S.
; Silva, Anádria S.
; Silva, Christian
; Silva, Genilson A.R.
; Silva, Gisele O.
; Silva, Márcia C.R.
; Silva, Marcos J.
; Silva, Marcos J.
; Silva, Otávio L.M.
; Silva, Rafaela A.P.
; Silva, Saura R.
; Silva, Tania R.S.
; Silva-Gonçalves, Kelly C.
; Silva-Luz, Cíntia L.
; Simão-Bianchini, Rosângela
; Simões, André O.
; Simpson, Beryl
; Siniscalchi, Carolina M.
; Siqueira Filho, José A.
; Siqueira, Carlos E.
; Siqueira, Josafá C.
; Smith, Nathan P.
; Snak, Cristiane
; Soares Neto, Raimundo L.
; Soares, Kelen P.
; Soares, Marcos V.B.
; Soares, Maria L.
; Soares, Polyana N.
; Sobral, Marcos
; Sodré, Rodolfo C.
; Somner, Genise V.
; Sothers, Cynthia A.
; Sousa, Danilo J.L.
; Souza, Elnatan B.
; Souza, Élvia R.
; Souza, Marcelo
; Souza, Maria L.D.R.
; Souza-Buturi, Fátima O.
; Spina, Andréa P.
; Stapf, María N.S.
; Stefano, Marina V.
; Stehmann, João R.
; Steinmann, Victor
; Takeuchi, Cátia
; Taylor, Charlotte M.
; Taylor, Nigel P.
; Teles, Aristônio M.
; Temponi, Lívia G.
; Terra-Araujo, Mário H.
; Thode, Veronica
; Thomas, W.Wayt
; Tissot-Squalli, Mara L.
; Torke, Benjamin M.
; Torres, Roseli B.
; Tozzi, Ana M.G.A.
; Trad, Rafaela J.
; Trevisan, Rafael
; Trovó, Marcelo
; Valls, José F.M.
; Vaz, Angela M.S.F.
; Versieux, Leonardo
; Viana, Pedro L.
; Vianna Filho, Marcelo D.M.
; Vieira, Ana O.S.
; Vieira, Diego D.
; Vignoli-Silva, Márcia
; Vilar, Thaisa
; Vinhos, Franklin
; Wallnöfer, Bruno
; Wanderley, Maria G.L.
; Wasshausen, Dieter
; Watanabe, Maurício T.C.
; Weigend, Maximilian
; Welker, Cassiano A.D.
; Woodgyer, Elizabeth
; Xifreda, Cecilia C.
; Yamamoto, Kikyo
; Zanin, Ana
; Zenni, Rafael D.
; Zickel, Carmem S
.
Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.
Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.
https://doi.org/10.1590/2175-7860201566411
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10.
Errata de "Artrite enteropática no Brasil: dados do Registro Brasileiro de Espondiloartrites"
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Resende, Gustavo G.
; Lanna, Cristina C. D.
; Bortoluzzo, Adriana B.
; Gonçalves, Célio R.
; Sampaio-Barros, Percival D.
; Silva, José Antonio Braga da
; Ximenes, Antonio Carlos
; Bértolo, Manoel B.
; Ribeiro, Sandra L.E.
; Keiserman, Mauro
; Menin, Rita
; Skare, Thelma L.
; Carneiro, Sueli
; Azevedo, Valderílio F.
; Vieira, Walber P.
; Albuquerque, Elisa N.
; Bianchi, Washington A.
; Bonfiglioli, Rubens
; Campanholo, Cristiano
; Carvalho, Hellen M. S.
; Costa, Izaias P.
; Duarte, Angela P.
; Kohem, Charles L.
; Leite, Nocy
; Lima, Sonia A. L.
; Meirelles, Eduardo S.
; Pereira, Ivânio A.
; Pinheiro, Marcelo M.
; Polito, Elizandra
; Rocha, Francisco Airton C.
; Santiago, Mittermayer B.
; Sauma, Maria de Fátima L. C.
; Valim, Valeria
.
https://doi.org/10.1016/j.rbr.2014.03.016
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11.
Perfil do uso de drogas modificadoras de doença no Registro Brasileiro de Espondiloartrites
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Kohem, Charles L
; Bortoluzzo, Adriana B
; Gonçalves, Célio R
; Silva, José Antonio Braga da
; Ximenes, Antonio Carlos
; Bértolo, Manoel B.
; Ribeiro, Sandra L.E.
; Keiserman, Mauro
; Menin, Rita
; Skare, Thelma L.
; Carneiro, Sueli
; Azevedo, Valderílio F.
; Vieira, Walber P.
; Albuquerque, Elisa N.
; Bianchi, Washington A.
; Bonfiglioli, Rubens
; Campanholo, Cristiano
; Carvalho, Hellen M. S.
; Costa, Izaias Pereira da
; Duarte, Angela L.B. Pinto
; Leite, Nocy H.
; Lima, Sonia A.L.
; Meirelles, Eduardo S.
; Pereira, Ivânio A.
; Pinheiro, Marcelo M.
; Polito, Elizandra
; Resende, Gustavo G.
; Rocha, Francisco Airton C.
; Santiago, Mittermayer B.
; Sauma, Maria de Fátima L.C.
; Valim, Valéria
; Sampaio-Barros, Percival D
.
Introdução: Poucos estudos avaliaram o perfil do uso de drogas modificadoras de doença (DMD) em pacientes brasileiros com diagnóstico de espondiloartrite (EpA). Métodos: Um protocolo comum de investigação foi prospectivamente aplicado em 1505 pacientes classificados como EpA pelos critérios do Grupo Europeu de Estudo das Espondiloartrites (ESSG), acompanhados em 29 centros de referência em Reumatologia no Brasil. Variáveis clínicas e demográficas foram obtidas e avaliadas, analisando-se suas correlações com o uso das DMD metotrexato (MTX) e sulfasalazina (SSZ). Resultados: Pelo menos uma DMD foi utilizada por 73,6% dos pacientes, sendo MTX por 29,2% e SSZ por 21,7%, enquanto 22,7% utilizaram ambas as drogas. O uso do MTX foi significativamente associado ao acometimento periférico, e a SSZ foi associada ao comprometimento axial, sendo que as duas drogas foram mais utilizadas, isoladas ou combinadas, no comprometimento misto (p < 0,001). O uso de uma DMD esteve significativamente associado à etnia branca (MTX; p = 0,014), lombalgia inflamatória (SSZ; p = 0,002), dor em nádegas (SSZ; p = 0,030), cervicalgia (MTX; p = 0,042), artrite de membros inferiores (MTX; p < 0,001), artrite de membros superiores (MTX; p < 0,001), entesite (p = 0,007), dactilite (MTX; p < 0,001), doença inflamatória intestinal (SSZ; p < 0,001) e acometimento ungueal (MTX; p < 0,001). Conclusão: O uso de pelo menos uma DMD foi referido por mais de 70% dos pacientes numa grande coorte brasileira de pacientes com EpA, sendo o uso do MTX mais associado ao acometimento periférico e o uso da SSZ mais associado ao acometimento axial.
Introduction: Few studies have evaluated the profile of use of disease modifying drugs (DMD) in Brazilian patients with spondyloarthritis (SpA). Methods: A common research protocol was applied prospectively in 1505 patients classified as SpA by criteria of the European Spondyloarthropathies Study Group (ESSG), followed at 29 referral centers in Rheumatology in Brazil. Demographic and clinical variables were obtained and evaluated, by analyzing their correlation with the use of DMDs methotrexate (MTX) and sulfasalazine (SSZ). Results: At least one DMD was used by 73.6 % of patients: MTX by 29.2 % and SSZ by 21.7%, while 22.7 % used both drugs. The use of MTX was significantly associated with peripheral involvement, and SSZ was associated with axial involvement, and the two drugs were more administered, separately or in combination, in the mixed involvement (p < 0.001). The use of a DMD was significantly associated with Caucasian ethnicity (MTX , p = 0.014), inflammatory back pain (SSZ, p = 0.002) , buttock pain (SSZ, p = 0.030), neck pain (MTX, p = 0.042), arthritis of the lower limbs (MTX, p < 0.001), arthritis of the upper limbs (MTX, p < 0.001), enthesitis (p = 0.007), dactylitis (MTX, p < 0.001), inflammatory bowel disease (SSZ, p < 0.001) and nail involvement (MTX, p < 0.001). Conclusion: The use of at least one DMD was reported by more than 70% of patients in a large cohort of Brazilian patients with SpA, with MTX use more associated with peripheral involvement and the use of SSZ more associated with axial involvement.
https://doi.org/10.1016/j.rbr.2013.06.003
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12.
Artrite enteropática no Brasil: dados do registro brasileiro de espondiloartrites
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Resende, Gustavo G.
; Lanna, Cristina C. D.
; Bortoluzzo, Adriana B.
; Gonçalves, Célio R.
; Silva, José Antonio Braga da
; Ximenes, Antonio Carlos
; Bértolo, Manoel B.
; Ribeiro, Sandra L. E.
; Keiserman, Mauro
; Menin, Rita
; Skare, Thelma L.
; Carneiro, Sueli
; Azevedo, Valderílio F.
; Vieira, Walber P.
; Albuquerque, Elisa N.
; Bianchi, Washington A.
; Bonfiglioli, Rubens
; Campanholo, Cristiano
; Carvalho, Hellen M. S.
; Costa, Izaias P.
; Duarte, Angela P.
; Kohem, Charles L.
; Leite, Nocy
; Lima, Sonia A. L.
; Meirelles, Eduardo S.
; Pereira, Ivânio A.
; Pinheiro, Marcelo M.
; Polito, Elizandra
; Rocha, Francisco Airton C.
; Santiago, Mittermayer B.
; Sauma, Maria de Fátima L. C.
; Valim, Valeria
; Sampaio-Barros, Percival D.
.
As doenças inflamatórias intestinais (doença de Crohn e retocolite ulcerativa) apresentam manifestações extraintestinais em um quarto dos pacientes, sendo a mais comum a artrite enteropática. MÉTODOS: Estudo prospectivo, observacional e multicêntrico, realizado com pacientes de 29 centros de referência participantes do Registro Brasileiro de Espondiloartrites (RBE), que se incorpora ao grupo RESPONDIA (Registro Ibero-americano de Espondiloartrites). Dados demográficos e clínicos de 1472 pacientes foram colhidos, e aplicaram-se questionários padronizados de avaliação de mobilidade axial, de qualidade de vida, de envolvimento entesítico, de atividade de doença e de capacidade funcional. Exames laboratoriais e radiográficos foram realizados. Objetivamos, neste presente artigo, comparar as características clínicas, epidemiológicas, genéticas, imagenológicas, de tratamento e prognóstico de enteroartríticos com os outros espondiloartríticos nesta grande coorte brasileira. RESULTADOS: Foram classificados como enteroartrite 3,2% dos pacientes, sendo que 2,5% tinham espondilite e 0,7%, artrite (predomínio periférico). O subgrupo de indivíduos com enteroartrite apresentava maior prevalência de mulheres (P < 0,001), menor incidência de dor axial inflamatória (P < 0,001) e de entesite (P = 0,004). O HLA-B27 foi menos frequente no grupo de enteroartríticos (P = 0,001), mesmo se considerado apenas aqueles com a forma axial pura. Houve menor prevalência de sacroiliíte radiológica (P = 0,009) e também menor escore radiográfico (BASRI) (P = 0,006) quando comparado aos pacientes com as demais espondiloartrites. Também fizeram mais uso de corticosteroides (P < 0,001) e sulfassalasina (P < 0,001) e menor uso de anti-inflamatórios não hormonais (P < 0,001) e metotrexato (P = 0,001). CONCLUSÃO: Foram encontradas diferenças entre as enteroartrites e as demais espondiloartrites, principalmente maior prevalência do sexo feminino, menor frequência do HLA-B27, associados a uma menor gravidade do acometimento axial.
Inflammatory bowel diseases (Crohn's disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. METHODS: Prospective, observational, multicenter study with patients from 29 reference centers participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the assessment of axial mobility, quality of life, enthesitic involvement, disease activity and functional capacity were applied. Laboratory and radiographic examinations were performed. The aim of this study is to compare the clinical, epidemiological, genetic, imaging, treatment and prognosis characteristics of patients with enteropathic arthritis with other types of spondyloarthritis in a large Brazilian cohort. RESULTS: A total of 3.2% of patients were classified as having enteroarthritis, 2.5% had spondylitis and 0.7%, arthritis (peripheral predominance). The subgroup of individuals with enteroarthritis had a higher prevalence in women (P < 0.001), lower incidence of inflammatory axial pain (P < 0.001) and enthesitis (P = 0.004). HLA-B27 was less frequent in the group with enteroarthritis (P = 0.001), even when considering only those with the pure axial form. There was a lower prevalence of radiographic sacroiliitis (P = 0.009) and lower radiographic score (BASRI) (P = 0.006) when compared to patients with other types of spondyloarthritis. They also used more corticosteroids (P < 0.001) and sulfasalazine (P < 0.001) and less non-steroidal anti-inflammatory drugs (P < 0.001) and methotrexate (P = 0.001). CONCLUSION: There were differences between patients with enteroarthritis and other types of spondyloarthritis, especially higher prevalence of females, lower frequency of HLA-B27, associated with less severe axial involvement.
https://doi.org/10.1016/j.rbr.2013.04.001
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13.
Sistema automático para o controle eficiente de iluminação para multiplas lâmpadas fluorescentes
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Sba: Controle & Automação Sociedade Brasileira de Automatica
- Journal Metrics
Este artigo apresenta o desenvolvimento e a implementação de um sistema de iluminação automático multi-lâmpadas fluorescentes, com correção ativa do fator de potência de entrada utilizando a técnica dos valores médios instantâneos na forma digital, com capacidade de pré-aquecimento programável dos filamentos dos eletrodos e com controle de luminosidade. Além disso, o sistema proposto permite o gerenciamento e supervisão remota através de uma plataforma computacional amigável ao usuário, onde o sistema opera de forma automática ou manual, de acordo com a necessidade de cada ambiente e/ou do usuário, otimizando o consumo de energia elétrica.
This paper presents the development and implementation of an automatic multi-lamp lighting fluorescent system, with digital average current mode control for input power factor correction, based on electronic ballasts with capacity of ideal programmable preheating and dimming capabilities. Furthermore, the proposed system allows remote monitoring and management through a friendly software platform, where the system operates automatically or manually, according to the needs of each environment and/or user, optimizing the comsumption of electrical energy.
14158 downloads
14.
Baixa prevalência das manifestações extra-articulares renais, cardíacas, pulmonares e neurológicas nas espondiloartrites: análise do Registro Brasileiro de Espondiloartrites
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Rodrigues, Carlos Ewerton Maia
; Vieira, Walber Pinto
; Bortoluzzo, Adriana B.
; Gonçalves, Célio Roberto
; Silva, José Antonio Braga da
; Ximenes, Antonio Carlos
; Bértolo, Manoel B.
; Ribeiro, Sandra L. E.
; Keiserman, Mauro
; Menin, Rita
; Skare, Thelma L.
; Carneiro, Sueli
; Azevedo, Valderílio F.
; Albuquerque, Elisa N.
; Bianchi, Washington A.
; Bonfiglioli, Rubens
; Campanholo, Cristiano
; Carvalho, Hellen M. S.
; Costa, Izaias P.
; Duarte, Angela P.
; Kohem, Charles L.
; Leite, Nocy H.
; Lima, Sonia A. L.
; Meirelles, Eduardo S.
; Pereira, Ivânio A.
; Pinheiro, Marcelo M.
; Polito, Elizandra
; Resende, Gustavo G.
; Rocha, Francisco Airton C.
; Santiago, Mittermayer B.
; Sauma, Maria de Fátima L. C.
; Valim, Valeria
; Sampaio-Barros, Percival D.
.
OBJETIVO: Descrever as manifestações extra-articulares (cardíacas, renais, pulmonares e neurológicas) geralmente não relacionadas às espondiloartrites (EpA) em uma grande coorte de pacientes brasileiros. MÉTODOS: Este estudo retrospectivo analisou 1.472 pacientes com o diagnóstico de EpA atendidos em 29 centros distribuídos pelas cinco principais regiões geográficas do Brasil, integrantes do Registro Brasileiro de Espondiloartrites. Todos os pacientes foram avaliados para a prevalência das principais manifestações extra-articulares (cardíacas, renais, pulmonares e neurológicas), divididas por diagnóstico [espondilite anquilosante (EA), artrite psoriásica (AP), artrite reativa (ARe), artrite associada a doença inflamatória intestinal (DII), EpA indiferenciada (EI) e EpA juvenil] e por forma clínica (axial, periférica, mista e entesítica). RESULTADOS: Dentre os pacientes avaliados com EpA, 963 apresentavam EA, 271 AP, 49 ARe, 48 artrite associada a DII, 98 EI e 43 EpA juvenil. Acometimento cardíaco foi observado em 44 pacientes (3,0%), seguido por acometimento pulmonar em 19 (1,3%), renal em 17 (1,2%) e neurológico em 13 pacientes (0,9%). A maioria dos casos de acometimento visceral ocorreu nos pacientes com EA ou AP e naqueles com forma clínica mista (axial e periférica) e/ou predominantemente axial. CONCLUSÃO: As manifestações extra-articulares cardíacas, renais, pulmonares e neurológicas são muito pouco frequentes nas EpA, variando de 0,9%-3% nesta grande coorte brasileira, estando mais associadas a EA e AP.
OBJECTIVE: To describe the extra-articular manifestations (cardiac, renal, pulmonary, and neurological), usually not related to spondyloarthritis (SpA), in a large cohort of Brazilian patients. MATERIALS AND METHODS: This retrospective study analyzed 1,472 patients diagnosed with SpA and cared for at 29 health care centers distributed in the five major geographic regions in the country, participating in the Brazilian Registry of Spondyloarthritis (BRS). All patients were assessed for the prevalence of major extra-articular manifestations (cardiac, renal, pulmonary, and neurological), classified according to the diagnosis [ankylosing spondylitis (AS), psoriatic arthritis (PsA), reactive arthritis (ReA), arthritis associated with inflammatory bowel disease (IBD), undifferentiated spondyloarthritis (uSpA), and juvenile SpA], and according to the clinical presentation (axial, peripheral, mixed, and enthesitis). RESULTS: Of the patients with SpA assessed, 963 had AS, 271 PsA, 49 ReA, 48 arthritis associated with IBD, 98 uSpA, and 43 juvenile SpA. Cardiac involvement was reported in 44 patients (3.0%), pulmonary involvement in 19 (1.3%), renal involvement in 17 (1.2%), and neurological involvement in 13 patients (0.9%). Most patients with visceral involvement had AS or PsA, and the mixed (axial + peripheral) and/or predominantly axial clinical form. CONCLUSION: Cardiac, renal, pulmonary, and neurological extra-articular manifestations are quite infrequent in SpA, ranging from 0.9% to 3% in this large Brazilian cohort, and affected predominantly patients with AS and PsA.
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Intervenção coronária percutânea no hospital Vera Cruz de Campinas: resultados de cinco anos de experiência
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Gioppato, Silvio
; Cantarelli, Marcelo J. C.
; Conforti, Thomas Borges
; Castello Jr., Helio J.
; Gonçalves, Silvio Luiz Pollini
; Carvalho, Gustavo Sergio
; Spis, Leandro Nista
; Calil, David Eduardo
; Nicastro, Mauricio T.
; Conforti, Pedro A. P.
; Baucchi, Antenor
; Verri, Vitorio
; Verri, Guilherme C.
; Lourenço, Mayara Brunheroto
; Sampaio, Carlos Eduardo
; Lopes, Fabio Rainha
; Lopes, Mauricio Marson
; Padovani, Ronaldo
; Vedovello, Thiago Jair
; Otero, Nyder Rodrigues
.
INTRODUÇÃO: A intervenção coronária percutânea (ICP) tem importante papel no tratamento da doença arterial coronária, em decorrência do desenvolvimento tecnológico e da ampliação de sua utilização nos cenários clínicos de maior complexidade. Apresentamos a experiência de serviço de hemodinâmica que iniciou sua atividade há cinco anos, localizado em hospital em Campinas (SP). MÉTODOS: De 2006 a 2011, 518 pacientes foram submetidos consecutivamente a ICP no Hospital Vera Cruz e incluídos neste estudo. As características clínicas, angiográficas e do procedimento e os resultados clínicos hospitalares foram analisados. RESULTADOS: A média de idade dos pacientes foi de 65,8 + 12,2 anos, 73,5% eram do sexo masculino, 29,9% eram diabéticos e metade dos procedimentos foi realizada na vigência de síndrome coronária aguda. No total, foram tratadas 890 lesões (74% delas do tipo B2/C), sendo implantado 1,6 stent/paciente, 37,1% dos quais farmacológicos. O diâmetro e o comprimento do stent foram, respectivamente, de 3,01 + 0,53 mm e 23,2 + 7 mm. O sucesso do procedimento foi de 93,6%, óbito ocorreu em 2,9% dos pacientes, acidente vascular cerebral em 0,8%, infarto do miocárdio em 3,5%, ICP de urgência em 0,8%, e trombose de stent em 0,97%. Hipertensão arterial [odds ratio (OR) 4,48, intervalo de confiança de 95% (IC 95%) 1,32-15,16; P = 0,016] e diabetes (OR 7,24, IC 95% 1,69-31,05; P = 0,008) foram preditores independentes de eventos adversos cardíacos e cerebrovasculares maiores (ECCAM) hospitalares. CONCLUSÕES: O sucesso do procedimento e a baixa ocorrência de ECCAM demonstram a efetividade e a segurança da ICP no atendimento de pacientes da prática clínica diária tratados em um novo serviço de cardiologia intervencionista, inserido em hospital localizado fora da capital do Estado de São Paulo.
BACKGROUND: Percutaneous coronary intervention (PCI) plays an important role in the treatment of coronary artery disease, as a result of technological development and its wide application in different clinical scenarios of greater complexity. We present data from a cath lab that started its activity five years ago at a private hospital in the city of Campinas (SP). METHODS: From 2006 to 2011, 518 consecutive patients were submitted to PCI at the Vera Cruz Hospital and were included in this study. Clinical, angiographic and procedural characteristics and the in-hospital clinical outcomes were analyzed. RESULTS: Patient average age was 65.8 + 12.2 years, 73.5% were male, 29.9% were diabetics and half of procedures were performed during an acute coronary syndrome. A total of 890 lesions (74% B2/C type) were treated with 1.6 stents/patient, 37.1% of them were drug eluting stents. Stent diameter and length were 3.01 + 0.53 mm and 23.2 + 7 mm, respectively. The procedure success was 93.6%, death occurred in 2.9% of the patients, stroke in 0.8%, myocardial infarction in 3.5%, reintervention in 0.8% and stent thrombosis in 0.97%. Hypertension [odds ratio (OR) 4.48, 95% confidence interval (95% CI) 1.32-15.16; P = 0.016] and diabetes (OR 7.24, 95% CI 1.69-31.05; P = 0.008) were independent predictors of in-hospital major adverse cardiac and cerebrovascular events (MACCE). CONCLUSIONS: The overall procedural success and low incidence of MACCE demonstrated the efficacy and safety of PCI in the daily clinical practice in a new interventional cardiology service, localized in a hospital outside the capital of the state of São Paulo.
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