Resumen La ciudad de Esperanza (Provincia de Santa Fe, Argentina) posee espacios verdes tales como parques, plazas y plazoletas que constituyen áreas de esparcimiento y garantizan el desarrollo humano en equilibrio con la naturaleza. Para el conocimiento de estos espacios verdes es fundamental conocer la superficie que ocupan, las especies vegetales, el estado de conservación de las plantas y el manejo que reciben, especialmente las leñosas. Considerando la importancia que el arbolado urbano tiene en esta ciudad se realizó un censo con el objetivo de evaluar las principales características de la flora leñosa de los espacios verdes. Se tomaron datos de las especies existentes, estado sanitario e intervenciones silviculturales. A partir de esta información se propusieron intervenciones silviculturales apropiadas. Finalmente se evaluó la disponibilidad de espacios verdes por habitante y la cantidad de habitantes por árbol. El 74 % de los árboles correspondió a especies exóticas, el estado sanitario en general resultó bueno y el 57 % de los árboles no tuvo ningún tipo de intervención silvicultural evidente. Cada habitante dispone en promedio de 7,64 m2 de espacio verde y la cantidad de habitantes por árbol fue 18,8. Los datos obtenidos constituyen el primer censo de especies leñosas de la infraestructura verde de Esperanza. Se propone aumentar la superficie de espacios verdes y promover la plantación, especialmente con especies nativas.

Abstract Esperanza City (Santa Fe, Argentina) has green spaces such as parks, squares and small squares devoted to recreational areas and guarantee human development in balance with nature. To fully understand these green spaces, it is essential to know the area they occupy, the plant species included as well as their health condition and the management they receive, particularly the woody ones. Due to the importance given to urban trees in this city, a census was carried out to evaluate the main features of the woody flora int these green spaces. The data collected include: existing species, their health status and silvicultural interventions. Based upon this information, suitable silvicultural interventions were proposed. Finally, the availability of green spaces per inhabitant and the number of inhabitants per tree were evaluated. The results showed that 74 % of the trees corresponded to exotic species with a good general health status and 57 % of the trees showed nom evident silvicultural intervention. There exists an average of 7.64 m2 of green space per inhabitant and 18.8 inhabitants per tree. The data obtained become the first census of woody species of the Esperanza City green infrastructure. It is proposed to increase green space areas and promote planting, especially using native species.

A investigação fitoquímica dos frutos maduros de Solanum caavurana Vell. (Solanaceae) forneceu um novo alcaloide esteroidal do tipo espirosolano, caavuranamida, juntamente com os alcaloides 4-tomatiden-3-ona e 5α-tomatidan-3-ona. Suas estruturas foram elucidadas através de métodos espectroscópicos. As atividades antiproliferativa e antimicrobiana para o extrato etanólico e subfrações provenientes de partição e de extração ácido-base foram investigadas. A caavuranamida apresentou atividade antibacteriana similar ao controle positivo cloranfenicol contra Rhodococcus equi.

Phytochemical investigation of the ripe fruits of Solanum caavurana Vell. (Solanaceae) afforded a novel steroidal alkaloid with spirosolane-type skeleton, named as caavuranamide, together with the alkaloids 4-tomatiden-3-one and 5α-tomatidan-3-one. Their structures were elucidated on the basis of spectroscopic methods. The antiproliferative and antimicrobial activities for the ethanolic extract, sub-fractions obtained from partition and acid-base treatment were also evaluated. Caavuranamide showed antibacterial activity similar to the chloramphenicol positive control against Rhodococcus equi.

Round holes in the ears of MRL mice tend to close with characteristics of regeneration believed to be absent in other mouse strains (e.g., C57BL/6). We evaluated the kinetics and the histopathology of ear wound closure in young (8 weeks old) C57BL/6 and BALB/c mice. We also used middle-aged (40 weeks old) C57BL/6 mice to evaluate the influence of aging on this process. A circular through-and-through hole was made in the ear, photographs were taken at different times after injury and wound area was measured with digital analysis software. The percentages of closed area measured on day 100 were: 23.57 ± 8.66% for young BALB/c mice, 56.47 ± 7.39% for young C57BL/6 mice, and 75.31 ± 23.65% for middle-aged C57BL/6 mice. Mice were sacrificed on days 1, 3, 5, 25, 44, and 100 for histological evaluation with hematoxylin and eosin, Gomori’s trichrome, periodic acid-Schiff, or picrosirius red staining. In young mice of both strains, healing included re-epithelialization, chondrogenesis, myogenesis, and collagen deposition. Young C57BL/6 and BALB/c mice differed in the organization of collagen fibers visualized using picrosirius-polarization. Sebaceous glands and hair follicles regenerated and chondrogenesis was greater in young C57BL/6 mice. In middle-aged C57BL/6 mice all aspects of regeneration were depressed. The characteristics of regeneration were present during ear wound healing in both young BALB/c and young C57BL/6 mice although they differed in intensity and pattern. Greater ear wound closure in middle-aged C57BL/6 mice was not correlated with regeneration.