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Acute kidney injury: the experience of a tertiary center of Pediatric Nephrology injury
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Figueiredo, Carolina Silva

; Rocha, Ana Margarida Neto da

; Silva, Liane Maria Correia Rodrigues da Costa Nogueira

; Faria, Maria do Sameiro Pinto César de

; Tavares, Teresa Maria Tavares Vieira da Costa

; Mota, Maria da Conceição Oliveira Costa

Brazilian Journal of Nephrology

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sep 2024, Volume 46 N. 3 elocation e20240012

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Introduction: Acute kidney injury (AKI) is an abrupt deterioration of kidney function. The incidence of pediatric AKI is increasing worldwide, both in critically and non-critically ill settings. We aimed to characterize the presentation, etiology, evolution, and outcome of AKI in pediatric patients admitted to a tertiary care center. Methods: We performed a retrospective observational single-center study of patients aged 29 days to 17 years and 365 days admitted to our Pediatric Nephrology Unit from January 2012 to December 2021, with the diagnosis of AKI. AKI severity was categorized according to Kidney Disease Improving Global Outcomes (KDIGO) criteria. The outcomes considered were death or sequelae (proteinuria, hypertension, or changes in renal function at 3 to 6 months follow-up assessments). Results: Forty-six patients with a median age of 13.0 (3.5–15.5) years were included. About half of the patients (n = 24, 52.2%) had an identifiable risk factor for the development of AKI. Thirteen patients (28.3%) were anuric, and all of those were categorized as AKI KDIGO stage 3 (p < 0.001). Almost one quarter (n = 10, 21.7%) of patients required renal replacement therapy. Approximately 60% of patients (n = 26) had at least one sequelae, with proteinuria being the most common (n = 15, 38.5%; median (P25–75) urinary protein-to-creatinine ratio 0.30 (0.27–0.44) mg/mg), followed by reduced glomerular filtration rate (GFR) (n = 11, 27.5%; median (P25–75) GFR 75 (62–83) mL/min/1.73 m2). Conclusions: Pediatric AKI is associated with substantial morbidity, with potential for proteinuria development and renal function impairment and a relevant impact on long-term prognosis. Introduction (AKI worldwide noncritically non settings presentation etiology evolution center Methods singlecenter single 2 1 36 201 2021 (KDIGO criteria proteinuria, (proteinuria hypertension followup follow up assessments. assessments . assessments) Results Fortysix Forty six 130 13 0 13. 3.5–15.5 35155 5 15 (3.5–15.5 included n 24 52.2% 522 52 28.3% 283 28 (28.3% anuric p 0.001. 0001 0.001 001 0.001) 10 21.7% 217 21 7 therapy 60 26 38.5% 385 38 P25–75 P2575 P P25 (P25–75 proteintocreatinine protein creatinine 030 30 0.3 0.27–0.44 027044 27 44 (0.27–0.44 mg/mg, mgmg mg/mg , mg mg/mg) (GFR 11 27.5% 275 62–83 6283 62 83 (62–83 mLmin173 mLmin mL min 73 mL/min/1.7 m2. m2 m m2) Conclusions morbidity longterm long term prognosis 20 202 3.5–15. 3515 (3.5–15. 52.2 28.3 (28.3 000 0.00 00 21.7 38.5 P25–7 P257 P2 (P25–7 03 0. 0.27–0.4 02704 4 (0.27–0.4 27.5 62–8 628 8 (62–8 mLmin17 mL/min/1. 3.5–15 351 (3.5–15 52. 28. (28. 0.0 21. 38. P25– (P25– 0.27–0. 0270 (0.27–0. 27. 62– (62– mLmin1 mL/min/1 3.5–1 35 (3.5–1 (28 (P25 0.27–0 027 (0.27–0 (62 mL/min/ 3.5– (3.5– (2 (P2 0.27– 02 (0.27– (6 mL/min 3.5 (3.5 ( (P 0.27 (0.27 3. (3. 0.2 (0.2 (3 (0. (0

RESUMO Introdução: Insuficiência renal aguda (IRA) é uma deterioração abrupta da função renal. A incidência de IRA pediátrica está aumentando em todo o mundo, em ambientes críticos e não críticos. Nosso objetivo foi caracterizar apresentação, etiologia, evolução e desfechos da IRA em pacientes pediátricos internados em um centro de atendimento terciário. Métodos: Realizamos estudo retrospectivo observacional de centro único de pacientes com idade entre 29 dias a 17 anos e 365 dias internados em nossa Unidade de Nefrologia Pediátrica, de janeiro de 2012 a dezembro de 2021, com diagnóstico de IRA. A gravidade da IRA foi categorizada de acordo com os critérios do Kidney Disease Improving Global Outcomes (KDIGO). Os desfechos considerados foram óbito ou sequelas (proteinúria, hipertensão ou alterações na função renal em avaliações de acompanhamento de 3 a 6 meses). Resultados: Incluímos 46 pacientes com idade mediana de 13,0 (3,5–15,5) anos. Cerca de metade (n = 24; 52,2%) apresentou um fator de risco identificável para o desenvolvimento de IRA. Treze pacientes (28,3%) eram anúricos; todos foram classificados como IRA KDIGO 3 (p < 0,001). Quase um quarto (n = 10; 21,7%) dos pacientes necessitaram de terapia renal substitutiva. Aproximadamente 60% (n = 26) apresentou pelo menos uma sequela, sendo proteinúria a mais comum (n = 15; 38,5%; mediana (P25–75) da relação proteína/creatinina urinária 0,30 (0,27–0,44) mg/mg), seguida de taxa de filtração glomerular (TFG) reduzida (n = 11; 27,5%; mediana (P25–75) da TFG 75 (62–83) mL/min/1,73 m2). Conclusões: A IRA pediátrica está associada à morbidade substancial, com potencial para desenvolvimento de proteinúria e comprometimento da função renal e impacto relevante no prognóstico de longo prazo. Introdução (IRA mundo apresentação etiologia terciário Métodos 2 1 36 Pediátrica 201 2021 KDIGO. . (KDIGO) proteinúria, (proteinúria meses. meses meses) Resultados 4 130 13 0 13, 3,5–15,5 35155 5 15 (3,5–15,5 n 24 52,2% 522 52 28,3% 283 28 (28,3% anúricos p 0,001. 0001 0,001 001 0,001) 10 21,7% 217 21 7 substitutiva 60 26 sequela 38,5% 385 38 P25–75 P2575 P P25 (P25–75 proteínacreatinina proteína creatinina 030 30 0,3 0,27–0,44 027044 27 44 (0,27–0,44 mg/mg, mgmg mg/mg , mg mg/mg) (TFG 11 27,5% 275 62–83 6283 62 83 (62–83 mLmin173 mLmin mL min 73 mL/min/1,7 m2. m2 m m2) Conclusões substancial prazo 20 202 (KDIGO 3,5–15, 3515 (3,5–15, 52,2 28,3 (28,3 000 0,00 00 21,7 38,5 P25–7 P257 P2 (P25–7 03 0, 0,27–0,4 02704 (0,27–0,4 27,5 62–8 628 8 (62–8 mLmin17 mL/min/1, 3,5–15 351 (3,5–15 52, 28, (28, 0,0 21, 38, P25– (P25– 0,27–0, 0270 (0,27–0, 27, 62– (62– mLmin1 mL/min/1 3,5–1 35 (3,5–1 (28 (P25 0,27–0 027 (0,27–0 (62 mL/min/ 3,5– (3,5– (2 (P2 0,27– 02 (0,27– (6 mL/min 3,5 (3,5 ( (P 0,27 (0,27 3, (3, 0,2 (0,2 (3 (0, (0

https://doi.org/10.1590/2175-8239-jbn-2024-0012en

Consenso mexicano de cáncer mamario. Manejo del cáncer de mama temprano
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Bargalló-Rocha, Juan E.

; Aguilar-Villanueva, Sergio

; Ahumada-Pámanes, Carolina

; Arce-Salinas, Claudia

; Álvarez-Cano, Alethia

; Baley-Spindel, Isaac

; Bautista-Piña, Verónica

; Cervantes-Sánchez, Guadalupe

; Chávez-MacGregor, Mariana

; Esparza-Arias, Nereida

; Figueroa-Padilla, Jonathán

; Flores-Balcázar, Christian H.

; Flores-Moreno, Sonia Ma.

; Maffuz-Aziz, Antonio

; Maldonado-Magos, Federico

; Lara-Tamburrino, Ma. del Carmen

; Lluch-Hernández, Ana

; Navarro-Santiesteban, Sarina

; Pérez-Sánchez, Víctor M.

; Poitevín-Chacón, Adela

; Ruvalcaba-Limón, Eva

; Salas-González, Efraín

; Sarricolea-Puch, Amelia

; Soto-Pérez-de-Celis, Enrique

; Torrecillas-Torres, Laura

; Valero-Castillo, Vicente

; Villaseñor-Navarro, Yolanda

; Chávarri-Guerra, Yanin

; Cárdenas-Sánchez, Jesús

Gaceta mexicana de oncología

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mar 2024, Volume 23 N. 1 Pages 30 - 61

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Breast cancer, in early stages, has specific surgical, radiotherapy, and systemic management. This type of cancer includes ductal carcinoma in situ and breast cancers in stages I, IIA, IIB, and IIIA. This tenth update of the Mexican Breast Cancer Consensus addressed the management of early stages. The dissemination of this consensus contributes to the updating and homogeneity of breast cancer management criteria. This article aims to present the update in the multidisciplinary management of breast cancer.

Resumen El cáncer mamario en estadios tempranos tiene un manejo local (quirúrgico y radioterapia) y sistémico específico. Este tipo de cáncer incluye el carcinoma ductal in situ y los cánceres de mama en estadios I, IIA, IIB y IIIA. Esta décima actualización del Consenso Mexicano de Cáncer Mamario abordó el manejo de los estadios tempranos. La difusión de este consenso contribuye a la actualización y homogeneidad de criterios de manejo del cáncer mamario y el objetivo de este artículo es presentar la actualización en el manejo multidisciplinario del cáncer de mama.

https://doi.org/10.24875/j.gamo.m24000261

Effect of Ceramic Thickness on the Bond Strength to Resin-Luting Agents before and after Thermal Cycling ResinLuting Resin Luting
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Souza, Carolina Rodrigues de

; Costa, Ana Rosa

; Borges, Lincoln Pires Silva

; Ferraz, Analia Gabriella Borges

; consani, Rafael Leonardo Xediek

; Pacheco, Rafael Rocha

; Correr, Américo Bortolazzo

; Correr-Sobrinho, Lourenço

Brazilian Dental Journal

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2024, Volume 35 elocation e24-5619

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study investigated microshear bond strength (µSBS) of two (2) dual-cured resin-luting agents (RelyX™ Ultimate and RelyX™ U200) when photoactivated through varying thicknesses of lithium disilicate, with or without thermal cycling. Discs of IPS e.max Press of 0.5, 1.5, and 2 mm in thickness were obtained. Elastomer molds (3.0 mm in thickness) with four cylinder-shaped orifices 1.0 mm in diameter, were placed onto the ceramic surfaces and filled with resin-luting agents. A Mylar strip, glass plate, and load of 250 grams were placed over the filled mold. The load was removed and the resin-luting agents were photoactivated through the ceramics using a single-peak LED (Radii Plus.) All samples were stored in distilled water at 37oC for 24 h. Half of the samples were subjected to thermal cycling (3,000 cycles; 5ºC and 55ºC). All samples were then submitted to µSBS test using a universal testing machine (Instron 4411) at a crosshead speed of 0.5 mm/min. Data were submitted to three-way ANOVA and Tukey post-hoc test (α=0.05). The mean µSBS at 24 h was significantly higher than after thermal cycling (p<0.05). No statistical difference was found between resin-luting agents (p > 0.05). The mean µSBS for groups photoactivated through 0.5 mm ceramic were significantly higher than 1.5 mm and 2.0 mm (p < 0.05). In conclusion, increased ceramic thicknesses reduced the bond strength of tested resin-luting agents to lithium disilicate. No differences were found between resin-luting agents. Thermal cycling reduced the bond strength of both resin-luting agents. (µSBS (2 dualcured dual cured resinluting resin luting RelyX (RelyX U200 U disilicate emax e max 05 0 5 15 1 obtained 3.0 30 3 (3. cylindershaped cylinder shaped 10 1. diameter strip plate 25 mold singlepeak single peak Radii Plus. Plus oC 3,000 3000 000 (3,00 cycles ºC 55ºC. 55ºC . 55ºC) Instron 4411 0. mmmin min mm/min threeway three way posthoc post hoc α=0.05. α005 α α=0.05 (α=0.05) p<0.05. p005 p p<0.05 (p<0.05) 0.05. 005 0.05 0.05) 20 2. conclusion ( U20 3. (3 3,00 300 00 (3,0 441 α00 α=0.0 (α=0.05 p00 p<0.0 (p<0.05 0.0 U2 3,0 (3, 44 α0 α=0. (α=0.0 p0 p<0. (p<0.0 3, 4 α=0 (α=0. p<0 (p<0. α= (α=0 p< (p<0 (α= (p< (α

Resumo: Este estudo investigou a resistência de união ao microcisalhamento (RUµC) de dois (2) agentes de cimentação de resina dual (RelyX™ Ultimate e RelyX™ U200) quando fotoativados através de diferentes espessuras de dissilicato de lítio, com ou sem ciclagem térmica. Discos do IPS e.max Press de 0,5, 1,5 e 2 mm de espessura foram obtidos. Moldes de elastômero (3,0 mm de espessura) com quatro orifícios cilíndricos de 1,0 mm de diâmetro foram colocados sobre as superfícies cerâmicas e preenchidos com agentes de cimentação de resina. Uma tira Mylar, placa de vidro e carga de 250 gramas foram colocadas sobre o molde preenchido. A carga foi removida e os agentes de cimentação resinosos foram fotoativados através da cerâmica usando um LED de pico-único (Radii Plus). Todas as amostras foram armazenadas em água deionizada a 37oC por 24 h. Metade das amostras foi submetida a ciclagem térmica (3.000 ciclos; 5ºC e 55ºC). Todas as amostras foram então submetidas ao teste de RUµC usando uma máquina de teste universal (Instron 4411) com velocidade de 0,5 mm/min. Os dados foram submetidos à Análise de Variância três fatores e ao teste post-hoc de Tukey (α = 0,05). A média de RUµC em 24 h foi significativamente maior do que após a ciclagem térmica (p < 0,05). Não houve diferença estatística entre os cimentos resinosos (p > 0,05). As médias de RUµC para grupos fotoativados através de cerâmica de 0,5 mm foram significativamente maiores do que 1,5 mm e 2,0 mm (p < 0,05). Em conclusão, o aumento da espessura da cerâmica reduziu a resistência de união dos agentes de cimentação resinosos ao dissilicato de lítio. Não foram encontradas diferenças entre os agentes de cimentação resinosos. A ciclagem térmica reduziu a resistência de união de ambos os agentes de cimentação resinosos. Resumo (RUµC (2 RelyX (RelyX U200 U lítio emax max 05 0 5 15 1 1, obtidos 3,0 30 3 (3, 10 Mylar 25 preenchido picoúnico pico único Radii Plus. Plus . Plus) oC 3.000 3000 000 (3.00 ciclos ºC 55ºC. 55ºC 55ºC) Instron 4411 0, mmmin min mm/min posthoc post hoc α 0,05. 005 0,05 0,05) p 20 2, conclusão ( U20 3, (3 3.00 300 00 (3.0 441 0,0 U2 3.0 (3. 44 3. 4

https://doi.org/10.1590/0103-6440202405619

Physiological changes induced by hardening in seedlings of eucalyptus as a function of growth stages
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Rocha, Maria Eunice Lima

; Malavasi, Ubirajara Contro

; Vera-Cruz, Maria Soraia Fortado

; Ristau, Ana Carolina Pinguelli

; Cordeiro, Noélle Khristinne

; Barbosa, Jaqueline de Araújo

Ciência Florestal

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2024, Volume 34 N. 1 elocation e71208

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Hardening appears as an interesting strategy to improve the quality of seedlings in forest nurseries, favoring their survival in the field. Thus, the objective of this research was to show the physiological alterations resulting from the application of methyl jasmonate and stem flexion in three stages of growth in Eucalyptus urograndis seedlings. The experiment was carried out in Marechal Cândido Rondon, Paraná, and Eucalyptus urograndis seedlings were used. Treatments consisted of weekly applications of methyl jasmonate (MeJA), daily imposition of stem flexion and a control treatment. Analyzes included quantification of flexural stiffness, lignin content in stems and roots, phenolic compounds in leaves and roots, electrolyte leakage in roots and field survival. In seedlings of Eucalyptus urograndis at 100 days after emergence (DAE) and at the three distances used to evaluate flexural rigidity, the highest averages were observed in seedlings submitted to chemical and mechanical treatments, coinciding with the increase in lignin content in the stem. In the roots, after quantifying the extravasation of electrolytes in Stage I, the means decreased with the application of treatments. In the field phase, there were no statistically significant differences between seedling survival assessments, quantified every 15 days, for a period of 90 days after planting. However, seedlings in Stage I were lost because they were too young and could not tolerate the stressful conditions observed in the field. nurseries Thus Rondon Paraná MeJA, MeJA , (MeJA) treatment stiffness 10 DAE (DAE rigidity treatments phase assessments 1 9 planting However (MeJA

RESUMO A rustificação surge como uma estratégia interessante a fim de melhorar a qualidade das mudas nos viveiros florestais, melhorando a sobrevivência a campo. Assim, o objetivo da pesquisa foi evidenciar alterações fisiológicas resultantes da aplicação de metil jasmonato e flexões caulinares nos três estádios de crescimento em mudas de Eucalyptus urograndis. O experimento foi conduzido em Marechal Cândido Rondon, no Estado do Paraná, e foram utilizadas mudas de Eucalyptus urograndis. Os tratamentos foram constituídos de aplicações semanais de metil jasmonato (MeJA) e imposição diária de flexões caulinares, além do tratamento controle. As análises consistiram na quantificação da rigidez flexural, lignina nos caules e raízes, compostos fenólicos nas folhas e raízes, perda de eletrólitos nas raízes e sobrevivência a campo. Em Eucalyptus urograndis com 100 dias após a emergência (DAE) e nas 3 distâncias utilizadas para avaliação da rigidez flexural, as maiores médias foram observadas em mudas submetidas aos tratamentos químico e mecânico coincidindo com o aumento do teor de lignina no caule. Nas raízes, após a quantificação da perda de eletrólitos, no estádio I, houve redução das médias com a aplicação dos tratamentos. Na fase de campo, não houve diferença significativa estatística entre as avaliações morfométricas a campo e a sobrevivência de mudas, quantificadas a cada 15 dias, até completarem 180 dias do plantio. Ainda, as mudas pertencentes ao estádio I foram perdidas, visto que estas eram muitos jovens e não toleraram as condições estressantes. florestais Assim Rondon Paraná MeJA (MeJA controle flexural 10 DAE (DAE caule 1 18 plantio Ainda perdidas estressantes

https://doi.org/10.5902/1980509871208

Systemic and local antiinflammatory effect of magnesium chloride in experimental arthritis
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Pinto, Ana Carolina Matias Dinelly

; Nunes, Rodolfo de Melo

; Carvalho, Waleska Vidal de Freitas

; Girão, Virgínia Claudia Carneiro

; Rocha, Francisco Airton Castro

Advances in Rheumatology

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2024, Volume 64 elocation 6

Abstract: En | Text: En | PDF: En

Abstract Objective Despite some knowledge gaps in scientific evidence, MgCl2 is largely used for pain relief in musculoskeletal diseases. Mg salts were shown to provide analgesia postoperatively in orthopedic surgery and low Mg levels were linked to arthritis development and severity. We determined the anti-inflammatory activity of MgCl2 in an acute arthritis model. Methods Mice received 0.1 mg/25μL Zymosan (Zy) or saline into the knees. Joint pain was evaluated using von Frey test; cell influx, and interleukin (IL)-1 level were assessed in joint lavage at 6 h. Synovia were excised for histopathology and analysis of immunoexpression of nuclear factor kappa B (NFκB) and tumor necrosis factor (TNF)-α. Groups (n = 6/group) received either 90 mg/kg MgCl2/100 μL or saline per os (systemic) or 500 μg/25 μL MgCl2 or saline intra-articularly (i.a.) 30 min prior to Zy. Results MgCl2 given either systemically or locally significantly reduced cell influx (p = 0.0012 and p = 0.0269, respectively), pain (p = 0.0005 and p = 0.0038, respectively), and intra-articular IL-1 level (p = 0.0391), as compared to saline. Systemic MgCl2 significantly decreased NFκB (p < 0.05) immmunoexpression, as compared to saline. Conclusion MgCl2 given systemically or locally displayed anti-inflammatory activity in a severe acute arthritis model reducing cell influx, pain, and cytokine release. MgCl2 operates at least partially via inhibiting NFκB activation. This is the first in vivo demonstration that MgCl2 decreases cytokine release in arthritis, prompting reduction of inflammation and pain relief. evidence MgCl diseases severity antiinflammatory anti inflammatory 01 0 1 0. mg25μL mgμL mg 25μL Zy (Zy knees test IL1 IL (IL)- h (NFκB TNFα. TNFα TNF α. α (TNF)-α n 6/group 6group group 9 mgkg kg MgCl2100 100 MgCl2/10 systemic (systemic 50 μg25 μg 25 μg/2 intraarticularly intra articularly i.a. ia i (i.a. 3 00012 0012 0.001 00269 0269 0.0269 respectively, respectively , respectively) 00005 0005 0.000 00038 0038 0.0038 intraarticular articular IL- 0.0391, 00391 0.0391 0391 0.0391) 0.05 005 05 immmunoexpression activation (IL) MgCl210 10 MgCl2/1 5 μg2 2 μg/ i.a (i.a 0001 001 0.00 0026 026 0.026 0000 000 0003 003 0.003 0039 0.039 039 0.0 00 (IL MgCl21 MgCl2/ 002 02 0.02 0.03 03

https://doi.org/10.1186/s42358-023-00346-8

A comprehensive physical functional assessment of survivors of critical care unit stay due to COVID-19 COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Volpe, Marcia Souza

; Santos, Ana Carolina Cardoso dos

; Gaspar, Sílvia

; Melo, Jade Lara de

; Harada, Gabriela

; Ferreira, Patrícia Rocha Alves

; Silva, Karina Ramiceli Soares da

; Souza, Natália Tiemi Simokomaki

; Toufen Junior, Carlos

; Chiavegato, Luciana Dias

; Amato, Marcelo Britto Passos

; Feltrim, Maria Ignez Zanetti

; Carvalho, Carlos Roberto Ribeiro de

Critical Care Science

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2024, Volume 36 elocation e20240284en

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To examine the physical function and respiratory muscle strength of patients - who recovered from critical COVID-19 – after intensive care unit discharge to the ward on Days one (D1) and seven (D7), and to investigate variables associated with functional impairment. Methods: This was a prospective cohort study of adult patients with COVID-19 who needed invasive mechanical ventilation, non-invasive ventilation or high-flow nasal cannula and were discharged from the intensive care unit to the ward. Participants were submitted to Medical Research Council sum-score, handgrip strength, maximal inspiratory pressure, maximal expiratory pressure, and short physical performance battery tests. Participants were grouped into two groups according to their need for invasive ventilation: the Invasive Mechanical Ventilation Group (IMV Group) and the Non-Invasive Mechanical Ventilation Group (Non-IMV Group). Results: Patients in the IMV Group (n = 31) were younger and had higher Sequential Organ Failure Assessment scores than those in the Non-IMV Group (n = 33). The short physical performance battery scores (range 0 - 12) on D1 and D7 were 6.1 ± 4.3 and 7.3 ± 3.8, respectively for the Non-Invasive Mechanical Ventilation Group, and 1.3 ± 2.5 and 2.6 ± 3.7, respectively for the IMV Group. The prevalence of intensive care unit-acquired weakness on D7 was 13% for the Non-IMV Group and 72% for the IMV Group. The maximal inspiratory pressure, maximal expiratory pressure, and handgrip strength increased on D7 in both groups, but the maximal expiratory pressure and handgrip strength were still weak. Only maximal inspiratory pressure was recovered (i.e., > 80% of the predicted value) in the Non-IMV Group. Female sex, and the need and duration of invasive mechanical were independently and negatively associated with the short physical performance battery score and handgrip strength. Conclusion: Patients who recovered from critical COVID-19 and who received invasive mechanical ventilation presented greater disability than those who were not invasively ventilated. However, they both showed marginal functional improvement during early recovery, regardless of the need for invasive mechanical ventilation. This might highlight the severity of disability caused by SARS-CoV-2. Objective COVID19 COVID 19 COVID-1 D (D1 D7, , (D7) impairment Methods noninvasive non highflow high flow sumscore, sumscore sum score, sum-score tests NonInvasive Non NonIMV . Results n 31 33. 33 33) range 12 61 6 1 6. 43 4 3 4. 73 7 7. 38 8 3.8 13 1. 25 2 5 2. 26 37 3.7 unitacquired acquired 72 weak i.e., ie i e (i.e. 80 value sex Conclusion ventilated However recovery SARSCoV2. SARSCoV2 SARSCoV SARS CoV SARS-CoV-2 COVID1 COVID- (D (D7 3. i.e. (i.e SARS-CoV- i.e SARS-CoV

RESUMO Objetivo: Examinar a função física e a força muscular respiratória de pacientes que se recuperaram da COVID-19 grave após a alta da unidade de terapia intensiva para a enfermaria nos Dias 1 e 7 e investigar as variáveis associadas ao comprometimento funcional. Métodos: Trata-se de estudo de coorte prospectivo de pacientes adultos com COVID-19 que necessitaram de ventilação mecânica invasiva, ventilação mecânica não invasiva ou cânula nasal de alto fluxo e tiveram alta da unidade de terapia intensiva para a enfermaria. Os participantes foram submetidos aos testes Medical Research Council sum-score, força de preensão manual, pressão inspiratória máxima, pressão expiratória máxima e short physical performance battery. Os participantes foram agrupados em dois grupos conforme a necessidade de ventilação mecânica invasiva: o Grupo Ventilação Mecânica Invasiva (Grupo VMI) e o Grupo Não Ventilação Mecânica Invasiva (Grupo Não VMI). Resultados: Os pacientes do Grupo VMI (n = 31) eram mais jovens e tinham pontuações do Sequential Organ Failure Assessment mais altas do que os do Grupo VMI (n = 33). As pontuações do short physical performance battery (intervalo de zero a 12) nos Dias 1 e 7 foram 6,1 ± 4,3 e 7,3 ± 3,8, respectivamente para o Grupo Não VMI, e 1,3 ± 2,5 e 2,6 ± 3,7, respectivamente para o Grupo VMI. A prevalência de fraqueza adquirida na unidade de terapia intensiva no Dia 7 foi de 13% para o Grupo Não VMI e de 72% para o Grupo VMI. A pressão inspiratória máxima, a pressão expiratória máxima e a força de preensão manual aumentaram no Dia 7 em ambos os grupos, porém a pressão expiratória máxima e a força de preensão manual ainda eram fracas. Apenas a pressão inspiratória máxima foi recuperada (ou seja, > 80% do valor previsto) no Grupo Não VMI. As variáveis sexo feminino, e necessidade e duração da ventilação mecânica invasiva foram associadas de forma independente e negativa à pontuação do short physical performance battery e à força de preensão manual. Conclusão: Os pacientes que se recuperaram da COVID-19 grave e receberam ventilação mecânica invasiva apresentaram maior incapacidade do que aqueles que não foram ventilados invasivamente. No entanto, os dois grupos de pacientes apresentaram melhora funcional marginal durante a fase inicial de recuperação, independentemente da necessidade de ventilação mecânica invasiva. Esse resultado pode evidenciar a gravidade da incapacidade causada pelo SARS-CoV-2. Objetivo COVID19 COVID 19 COVID-1 Métodos Tratase Trata sumscore, sumscore sum score, score sum-score . Resultados n 31 33. 33 33) intervalo 12 61 6 6, 43 4 3 4, 73 7, 38 8 3,8 13 1, 25 2 5 2, 26 37 3,7 72 fracas seja 80 previsto feminino Conclusão invasivamente entanto recuperação SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. SARS-CoV-2 COVID1 COVID- 3, SARS-CoV- SARS-CoV

https://doi.org/10.62675/2965-2774.20240284-en

Malignant tumors affecting the head and neck region in ancient times: Comprehensive study of the CRAB Database times
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AULESTIA-VIERA, Patricia Verónica

; RODRIGUES-FERNANDES, Carla Isabelly

; BRANDÃO, Thaís Bianca

; ROCHA, André Caroli

; VARGAS, Pablo Agustin

; LOPES, Marcio Ajudarte

; JOHNSON, Newell Walter

; KOWALSKI, Luiz Paulo

; RIBEIRO, Ana Carolina Prado

; SANTOS-SILVA, Alan Roger

Brazilian Oral Research

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2024, Volume 38 elocation e014

Abstract: En | Text: En | PDF: En

Abstract In the modern world, cancer is a growing cause of mortality, but archeological studies have shown that it is not exclusive to modern populations. The aim of this study is to examine the epidemiologic, social, and clinicopathologic features of head and neck cancers in ancient populations. To do this, we extracted all records that described malignant lesions in the head and neck region available in the Cancer Research in Ancient Bodies Database (CRAB). The estimated age, sex, physical condition of the remains (skeletonized, mummified), anatomic location of tumors, geographic location, chronology, tumor type, and methods of tumor diagnosis were collected. One hundred and sixty-seven cases were found, mostly originating from Europe (51.5%). Most records were of adults between 35 and 49 years of age (37.7%). The most involved site was the skullcap (60.4%), and the most common malignancies were metastases to the bone (65.3%) and multiple myeloma (17.4%). No primary soft tissue malignancies were registered. The results of our study indicate that head and neck cancers were present in ancient civilizations, at least since 500,000 BCE. The available data can help to improve the current understanding of the global distribution of head and neck cancer and its multidimensional impacts on populations in the contemporary world. world mortality epidemiologic social CRAB. CRAB . (CRAB) sex skeletonized, skeletonized (skeletonized mummified, mummified , mummified) tumors chronology type collected sixtyseven sixty seven found 51.5%. 515 51.5% 51 5 (51.5%) 3 4 37.7%. 377 37.7% 37 7 (37.7%) 60.4%, 604 60.4% 60 (60.4%) 65.3% 653 65 (65.3% 17.4%. 174 17.4% 17 (17.4%) registered civilizations 500000 500 000 500,00 BCE (CRAB 51.5 (51.5% 37.7 (37.7% 60.4 6 (60.4% 65.3 (65.3 17.4 1 (17.4% 50000 50 00 500,0 51. (51.5 37. (37.7 60. (60.4 65. (65. 17. (17.4 5000 0 500, (51. (37. (60. (65 (17. (51 (37 (60 (6 (17 (5 (3 ( (1

https://doi.org/10.1590/1807-3107bor-2024.vol38.0014

Electrocardiographic Findings Among Asymptomatic Adults With Haemophilia
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Camelo, Ricardo Mesquita

; Caram-Deelder, Camila

; Roncal, Carlos Guilherme Piscoya

; Duarte, Bruna Pontes

; Moura, Marilia Carolina Braga de

; Costa, Neuza Cavalcanti de Moraes

; Costa, Iris Maciel

; Vanderlei, Ana Maria

; Guimaraes, Tania Maria Rocha

; Gouw, Samantha

; Rezende, Suely Meireles

; Bom, Johanna van der

International Journal of Cardiovascular Sciences

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2024, Volume 37 elocation e20220179

Abstract: En | Text: En | PDF: En

Abstract Background: People with haemophilia (PwH) are living longer. Therefore, they can develop atherosclerotic cardiovascular disease (ASCVD). Electrocardiogram (ECG) alterations may be a sign of initial ASCVD before the occurrence of symptoms. Objective: To describe the prevalence of resting ECG alterations among PwH adults asymptomatic for ASCVD. Methods: PwH aged ≥ 30 years without previous ASCVD events were considered for the analysis. Resting ECG traces were analysed according to international reference values and the Brazilian Longitudinal Adult Health Study (ELSA-Brasil) results for asymptomatic Brazilian men. Based on the established normal values and using the QT index, we further described the altered ECGs as minor or major changes, according to the Minnesota Code. Differences between prevalences were evaluated by Pearson's χ2 test. Differences between medians were evaluated by the Mann-Whitney U test. A p-value < 0.05 was accepted as statistically significant. Results: A total of 64 PwH were included in the study. Median age was 44 years (interquartile range 35-52). Most patients had haemophilia A (81%) and 47% were severe. The prevalence of obesity, systemic arterial hypertension (SAH), diabetes mellitus (DM), and dyslipidaemia were 16%, 56%, 14%, and 72%, respectively. All the PwH had sinus rhythm, except for one, who had an implanted pacemaker due to idiopathic third-degree atrioventricular block. Altered ECGs were found in 25% and 30% of PwH, according to established criteria and ELSA-Brasil criteria, respectively. Major changes were found in eight (13%) PwH according to the Minnesota Code, including two ECGs with ischaemia-like wall inactivity. Conclusions: The prevalence of altered ECG varied from 25% to 30% among asymptomatic PwH. Background (PwH longer Therefore . (ASCVD) (ECG symptoms Objective Methods 3 analysis ELSABrasil ELSA Brasil (ELSA-Brasil men index Code Pearsons Pearson s χ test MannWhitney Mann Whitney pvalue p value 005 0 05 0.0 significant Results 6 study 4 interquartile 3552. 3552 35 52 35-52) 81% 81 (81% 47 severe obesity SAH, SAH , (SAH) DM, DM (DM) 16 16% 56 56% 14 14% 72 72% respectively rhythm one thirddegree third degree block 25 13% 13 (13% ischaemialike ischaemia like inactivity Conclusions (ASCVD 00 0. 355 5 35-52 8 (81 (SAH (DM 1 7 2 (13 35-5 (8 (1 35- (

https://doi.org/10.36660/ijcs.20220179

Manure application enhances the biomass production, phytochemical contents, antioxidant, and essential oil of Lippia dulcis production contents antioxidant
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Ribeiro, Fernanda Naiara Santos

; Rocha, Taina Teixeira

; Medeiros, Ana Paula Ribeiro

; Germano, Carolina Mesquita

; Assis, Rafael Marlon Alves de

; Carvalho, Alexandre Alves de

; Bertolucci, Suzan Kelly Vilela

; Pinto, José Eduardo Brasil Pereira

Revista Ciência Agronômica

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2024, Volume 55 elocation e20238873

Abstract: En | Text: En | PDF: En

ABSTRACT Lippia dulcis is a medicinal species used by communities in the Amazon region for the control of diabetes and as a tranquilizer. The objective of this study was to evaluate the plant biomass production, antioxidant defense, and chemical profiles of the phenolic compounds and essential oil of plants grown under different doses of cattle, quail, and chicken manure. Chicken and quail manure at a dose of 6 kg m-2 reached the highest values of dry weight and essential oil yield of the leaves and positively influenced bisabolol production. Cattle manure affected the content and yield of the essential oil of the inflorescences, the antioxidant defense performance, and the chemical composition of phenolic compounds and essential oil. Plants grown with cattle manure showed a linear increase in the amounts of these substances with increasing dose. Chicken and quail manure led to the highest values of these components at doses between 0 and 3 kg m-2. The evaluation of phenolic compounds and antioxidant defense showed the highest values at doses of 0, 1.5, and 3 kg m-2, regardless of the manure used. The essential oil concentration was higher in the inflorescences, and its total yield was higher in the leaves. The chemical composition varied between these vegetative organs. tranquilizer production m2 m 2 m- inflorescences performance m2. 2. 15 1 5 1.5 m2, 2, organs 1.

https://doi.org/10.5935/1806-6690.20240026

10.

Aprendizagem no internato na Atenção Básica em pediatria: olhar de egressos de Medicina pediatria
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Andrade, Maria Virgínia Lellis da Costa

; Pio, Danielle Abdel Massih

; Nonato, Ana Carolina

; Tonhom, Silvia Franco da Rocha

Revista Brasileira de Educação Médica

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2024, Volume 48 N. 1 elocation e023

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Introduction: Much is discussed about the training of health professionals prepared to meet the real needs of the population in the context of the Health Care System as recommended by the National Curriculum Guidelines, aiming at comprehensive care. Primary Care stands out as an important practice scenario in this context, including the internship, considering the autonomy of this phase. Objective: To analyze the perceptions of graduates of a medical course in relation to the pediatric internship in Primary Care. Method: Descriptive, exploratory research with a qualitative approach, developed through online interviews with medical graduates, graduated from a public higher education institution in the interior of São Paulo in 2018 and 2019. The data was analyzed using content analysis. Results and discussion: Eleven 2018 graduates and 15 2019 graduates were interviewed, with different professional activities since the end of the course. The category explored in this article will be “Learning opportunity during Primary Care in Pediatrics.” Experiencing Primary Care in Pediatrics provided different learning opportunities regarding the comprehensive care of the child, understanding the importance of its context and repercussions. Final Considerations: Knowing about the Health Care Network since the beginning of the course allowed students to understand the difficulties experienced in this network and the impact on care. The most prevalent and low-complexity situations are the reality of graduates in professional practice and need to be addressed during the teaching-learning process of the internship, favoring their performance. Introduction Guidelines phase Objective Method Descriptive approach 201 analysis discussion 1 interviewed Learning Pediatrics. child repercussions Considerations lowcomplexity low complexity teachinglearning teaching performance 20 2

Resumo Introdução: Muito se discute sobre a formação de profissionais de saúde preparados para atender às reais necessidades da população no contexto do Sistema Único de Saúde como preconizado pelas Diretrizes Curriculares Nacionais, almejando o cuidado integral. A Atenção Básica se destaca como importante cenário de prática nesse contexto, inclusive no internato, considerando a autonomia e o domínio dessa fase. Objetivo: Este estudo teve como objetivo analisar as percepções dos egressos de um curso médico em relação ao internato em pediatria na Atenção Básica. Método: Trata-se de pesquisa descritiva, exploratória com abordagem qualitativa, desenvolvida por meio de entrevistas on-line com egressos de Medicina, formados em uma instituição de ensino superior pública do interior paulista nos anos de 2018 e 2019. Os dados foram examinados por meio da análise de conteúdo temática. Resultado: Entrevistaram-se 11 egressos de 2018 e 15 egressos de 2019, com atuações profissionais diversas desde a finalização do curso. A categoria explorada neste artigo será “Oportunidade de aprendizagem durante a Atenção Básica em pediatria”. Vivenciar a Atenção Básica em pediatria oportunizou aprendizados diversos quanto ao cuidado integral da criança, compreendendo a importância de seu contexto e e de suas repercussões. Conclusão: Conhecer sobre a Rede de Atenção à Saúde desde o início do curso possibilitou entender as dificuldades vivenciadas nela e o impacto no cuidado. As situações mais prevalentes e de baixa complexidade são a realidade do egresso na atuação profissional e precisam ser abordadas durante o processo de ensino-aprendizagem do internato, favorecendo a atuação dele. Introdução Nacionais fase Objetivo Método Tratase Trata descritiva qualitativa online on line Medicina 201 2019 temática Resultado Entrevistaramse Entrevistaram 1 Oportunidade pediatria. . pediatria” criança repercussões Conclusão ensinoaprendizagem dele 20 2

https://doi.org/10.1590/1981-5271v48.1-2021-0378

11.

Translation and cultural adaptation of the Positive Aspects of Caregiving Scale for caregivers of people living with dementia in Brazilian context: a methodological study context
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Pavarini, Sofia Cristina Iost

; Gratão, Aline Cristina Martins

; Campos, Camila Rafael Ferreira

; Monteiro, Diana Quirino

; Barham, Elizabeth Joan

; Orlandi, Fabiana de Souza

; Martins, Gabriela

; Barbosa, Gustavo Carrijo

; Cruz, Keila Cristianne Trindade da

; Corrêa, Larissa

; Rocha, Luana Aparecida da

; Alves, Ludmyla Caroline de Souza

; Ottaviani, Ana Carolina

Sao Paulo Medical Journal

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2024, Volume 142 N. 2 elocation e2023325

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: The Positive Aspects of Caregiving (PAC) scale is used to assess psychosocial benefits provided to caregivers by the task of caring. The PAC scale consists of nine items, assessed using a five-point Likert scale, with higher values indicating greater positive perceptions and gains from the caregiving experience. OBJECTIVE: To translate and culturally adapt the PAC scale for informal Brazilian caregivers of people with dementia. DESIGN AND SETTING: A methodological study was conducted at the Federal University of São Carlos. METHODS: The following stages were carried out: Translation; Synthesis of the translations; Back-translation; Evaluation by an experts’ committee; and Pre-test. RESULTS: Two independent professionals translated the PAC scale. The consensus version was obtained by merging both translations, which were back-translated into English by a third translator. The expert committee comprised three specialists in the area and project researchers. All scale items presented a Content Validity Index of 1 (CVI = 1.0), and thus remained in the pre-final version of the instrument. The instrument was pre-tested with seven caregivers of people with dementia, the majority of whom were women (57.1%), with a degree of kinship corresponding to sons/daughters (57.1%) and an average age of 55.2 (± 4.1) years. The caregivers considered it clear and understandable and made no suggestions for changes. CONCLUSION: The PAC scale was translated and culturally adapted for use by informal caregivers of people with dementia in Brazil. However, a psychometric analysis of the instrument is necessary to provide normative data for this population group. BACKGROUND (PAC caring fivepoint five point experience OBJECTIVE SETTING Carlos METHODS out Translation translations Backtranslation Back translation Back-translation experts Pretest. Pretest Pre test. test Pre-test RESULTS backtranslated back translator researchers CVI 1.0, 10 1.0 , 0 1.0) prefinal pre final pretested tested 57.1%, 571 57.1% 57 sonsdaughters sons daughters (57.1% 552 55 2 55. ± ( 4.1 41 4 years changes CONCLUSION Brazil However group 1. 57.1 5 (57.1 4. 57. (57. (57 (5

https://doi.org/10.1590/1516-3180.2023.0325.r1.23012024

12.

Seaweed extract-based fertilizer and water stress on potato crops extractbased extract based
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Nunes, Gustavo Fonseca

; Moreira, Leticia Gonçalves

; Diniz, Nadia Mendes

; Jacinto, Ana Carolina Pires

; Prado, Jair Rocha do

; Charlo, Hamilton César de Oliveira

; Castoldi, Renata

Ciência e Agrotecnologia

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2024, Volume 48 elocation e018523

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Seaweed extract-based fertilizers are applied to mitigate the effects of stress on plants. In this study, we evaluated the effects of different concentrations of seaweed extract-based fertilizer and different irrigation depths on potato crops. The Ágata cultivar and the Markies cultivar were used to conduct two experiments simultaneously. A 4 × 4 experimental design was used, with four doses of seaweed extract-based fertilizer (0, 0.5, 1.0, and 4.0 L ha-1) and four irrigation depths (50%, 75%, 100%, and 125% of crop evapotranspiration); each treatment had three replicates. Leaves were collected 67 days after emergence to analyze macronutrients and micronutrients; additionally, the number of stems per plant and physiological variables were assessed. After harvesting, the number and weight of tubers in different classes were recorded. The differences in parameters among treatment groups were determined by analysis of variance using the F-test, and regression analysis was performed when a significant difference was recorded. The results showed that the contents of potassium, phosphorus, magnesium, and calcium in the leaves of the Ágata cultivar were below the optimal levels for the crop, irrespective of the irrigation level and the dose of seaweed extract-based fertilizer applied. The highest irrigation depths at 100% and 125% of crop evapotranspiration were associated with an increase in the number and weight of the large tubers of the Ágata and Markies cultivars. extractbased extract based plants study crops simultaneously 0, 0 (0 05 5 0.5 10 1 1.0 40 4. ha1 ha ha-1 50%, 50 (50% 75 75% 100 125 evapotranspiration) replicates 6 micronutrients additionally assessed harvesting recorded Ftest, Ftest F test, test F-test potassium phosphorus magnesium cultivars ( 0. 1. ha- 50% (50 7 12 (5

RESUMO Para mitigar os efeitos do estresse nas plantas, têm sido aplicados fertilizantes foliares à base de extrato de algas marinhas. Objetivou-se avaliar os efeitos de diferentes concentrações de fertilizante à base de extrato de algas marinhas e lâminas de irrigação na cultura da batata. Dois experimentos foram conduzidos simultaneamente, um com a cultivar Ágata e outro com a cultivar Markies. O delineamento experimental utilizado foi 4 × 4, com quatro doses de fertilizante à base de extrato de algas marinhas (0; 0,5; 1,0 e 4,0 L ha-1) e quatro lâminas de irrigação (50%, 75%, 100% e 125% da evapotranspiração da cultura), com três repetições. Aos 67 dias após a emergência foram coletadas folhas para análise de macro e micronutrientes e, também avaliaram-se: número de hastes por planta e variáveis fisiológicas. Após a colheita, avaliaram-se: número e peso dos tubérculos de diferentes classes. Os dados foram submetidos à análise de variância por meio do teste F e análise de regressão foi realizada quando houve diferença significativa. Os teores de potássio, fósforo, magnésio e cálcio nas folhas da cultivar Ágata ficaram abaixo dos níveis ótimos para a cultura, independente do nível de irrigação e da da dose de fertilizante aplicado. O fertilizante reduziu os efeitos do estresse hídrico, aumentando a eficiência fotoquímica das plantas de batata Markies. As maiores lâminas de irrigação em 100% e 125% da evapotranspiração da cultura levaram ao aumento do número e peso de tubérculos grandes para as cultivares Ágata e Markies. Objetivouse Objetivou se simultaneamente Markies 0 (0 0,5 05 5 10 1 1, 40 ha1 ha ha-1 50%, 50 (50% 75 75% 100 125 , cultura) repetições 6 avaliaramse avaliaram avaliaram-se fisiológicas colheita classes significativa potássio fósforo aplicado hídrico ( 0, ha- 50% (50 7 12 (5

https://doi.org/10.1590/1413-7054202448018523

13.

The role of chaperone-mediated autophagy in drug resistance chaperonemediated chaperone mediated
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Teixeira, Ana Beatriz da Silva

; Ramalho, Maria Carolina Clares

; Souza, Izadora de

; Andrade, Izabela Amélia Marques de

; Osawa, Isabeli Yumi Araújo

; Guedes, Camila Banca

; Oliveira, Beatriz Silva de

; Souza Filho, Cláudio Henrique Dahne de

; Silva, Tainá Lins da

; Moreno, Natália Cestari

; Latancia, Marcela Teatin

; Rocha, Clarissa Ribeiro Reily

Genetics and Molecular Biology

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2024, Volume 47 Suppl. 1 elocation e20230317

Abstract: En | Text: En | PDF: En

Abstract In the search for alternatives to overcome the challenge imposed by drug resistance development in cancer treatment, the modulation of autophagy has emerged as a promising alternative that has achieved good results in clinical trials. Nevertheless, most of these studies have overlooked a novel and selective type of autophagy: chaperone-mediated autophagy (CMA). Following its discovery, research into CMA’s contribution to tumor progression has accelerated rapidly. Therefore, we now understand that stress conditions are the primary signal responsible for modulating CMA in cancer cells. In turn, the degradation of proteins by CMA can offer important advantages for tumorigenesis, since tumor suppressor proteins are CMA targets. Such mutual interaction between the tumor microenvironment and CMA also plays a crucial part in establishing therapy resistance, making this discussion the focus of the present review. Thus, we highlight how suppression of LAMP2A can enhance the sensitivity of cancer cells to several drugs, just as downregulation of CMA activity can lead to resistance in certain cases. Given this panorama, it is important to identify selective modulators of CMA to enhance the therapeutic response. treatment trials Nevertheless chaperonemediated chaperone mediated CMA. . (CMA) discovery CMAs s rapidly Therefore turn tumorigenesis targets review Thus LAMPA LAMP A drugs cases panorama response (CMA

https://doi.org/10.1590/1678-4685-gmb-2023-0317

14.

The high biodiversity of benthic organisms in a coastal ecosystem revealed by an integrative approach
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Amaral, A. Cecília Z.

; Cunha, Beatriz P.

; Checon, Helio H.

; Godoy, Angélica S. de

; Silva, Camila F. da

; Corte, Guilherme N.

; Nogueira, João M. de M.

; Fukuda, Marcelo V.

; Steiner, Tatiana M.

; Kawauchi, Gisele Y.

; Turra, Alexander

; Denadai, Márcia R.

; Ferreira, Luciane

; Mendonça, Joel B. de

; Tavares, Marcos

; Leite, Fosca P. P.

; Costa, Mariana F. B.

; Siqueira, Silvana G. L.

; Vieira, Leandro M.

; Dias, Gustavo M.

; Teixeira, Joyce A.

; Rocha, Rosana M.

; Gusmão, Luciana C.

; Borges, Michela

; Alitto, Renata

; Machado, Fabrizio M.

; Passos, Flávio D.

; Cunha, Carlo M.

; Simone, Luiz R.L.

; Araujo, Ana Paula G.

; Carbayo, Fernando

; Bahia, Juliana

; Bulnes, Verónica N.

; Castello-Branco, Cristiana

; Hajdu, Eduardo

; Vilas-Boas, Ana Carolina

; Garraffoni, André R. S.

; Schockaert, Ernest

; Fonseca, Gustavo

; Domenico, Maikon Di

; Curini-Galletti, Marco

; Sørensen, Martin V.

; Hochberg, Rick

; Oliveira, Ana Julia F. C. de

; Zampieri, Bruna Del B.

; Chinelatto, Roberta M.

; Migotto, Alvaro E.

Biota Neotropica

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2024, Volume 24 N. 2 elocation e20231583

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Increasing habitat modification and species loss demand consistent efforts to describe and understand biodiversity patterns. The BIOTA/FAPESP Program was created in this context and it has been a successful initiative to promote studies on biodiversity and conservation in Brazil. The BIOTA/Araçá is an interdisciplinary project that provided a detailed evaluation of the biodiversity of Araçá Bay, a coastal seascape located on the North coast of the state of São Paulo, Southeast Brazil. The bay encompasses multiple habitats, such as beaches, mangroves, rocky shores, and a tidal flat, and provides important ecosystem services. Unfortunately, the bay is the subject of complex social-environmental conflicts that oppose economic, social, and environmental demands (i.e., the expansion of neighboring harbor activities vs. small-scale artisanal fisheries and protection of biodiversity). The present study presents a survey of the benthic species occurring in the different habitats of Araçá Bay, including data obtained during the BIOTA/Araçá project and previous assessments of the area. The benthic species play an important role in marine environments and studying the diversity of these organisms that live associated with the bottom is indispensable for comprehending the environment’s functioning. The macrofauna, meiofauna, and microorganisms associated with soft and hard bottom were listed, and additional information, such as the habitat and geographical distribution, were provided for each species. The checklist includes 826 species, almost 70% recorded during the BIOTA/Araçá project. The most speciose taxa were the annelids (225 spp.), mollusks (194 spp.), and crustaceans (177 spp.). Seven benthic species are endemic to Araçá Bay, 14 are considered threatened, and seven are economically exploited. Furthermore, the bay is the type locality of many taxa, and 11 new benthic species were described based on specimens sampled during the project. This project shows the importance of Araçá Bay as a unique biologically rich environment and highlights the need for conservation efforts in light of the current threats. patterns BIOTAFAPESP BIOTA FAPESP Brazil BIOTAAraçá Paulo beaches mangroves shores flat services Unfortunately socialenvironmental social economic i.e., ie i e (i.e. vs smallscale small scale biodiversity. . biodiversity) area s functioning macrofauna meiofauna listed information distribution 82 70 225 (22 spp., spp spp. , spp.) 194 (19 177 (17 spp.. 1 threatened exploited Furthermore threats i.e. (i.e 8 7 22 (2 19 (1 17 i.e 2 (

Resumo O aumento da modificação dos habitats e da perda de espécies demanda esforços consistentes para descrever e compreender os padrões de biodiversidade. O programa BIOTA/FAPESP foi criado nesse contexto e é uma iniciativa de sucesso para promover estudos em biodiversidade e conservação no Brasil. O BIOTA/Araçá é um projeto interdisciplinar que promoveu uma avaliação detalhada da biodiversidade da Baía do Araçá, um ecossistema costeiro localizado ao Norte do estado de São Paulo, Sudeste do Brasil. A baía engloba múltiplos habitats, tais como praias, manguezais, costões rochosos, e uma planície de maré, e também fornece importantes serviços ecossistêmicos. Infelizmente, a baía está sujeita à conflitos sócio-ambientais complexos que contrastam demandas econômicas, sociais e ambientais (i.e. a expansão das atividades do porto vizinho vs. a pesca artesanal de pequena escala e a proteção da biodiversidade). O presente estudo apresenta um levantamento das espécies bentônicas que ocorrem nos diferentes habitats da Baía do Araçá, incluindo dados obtidos durante o projeto BIOTA/Araçá e de investigações realizadas anteriormente na área. As espécies bentônicas desempenham um papel importante no ambiente marinho, e estudar a diversidade desses organismos que vivem associados ao fundo é indispensável para compreender o funcionamento do meio ambiente. A macrofauna, meiofauna, e microorganismos associados aos fundos consolidado e inconsolidado foram listados, e informações adicionais foram fornecidas para cada espécie, tais como a distribuição geográfica e nos habitats. O checklist inclui 826 espécies, quase 70% registradas durante o projeto BIOTA/Araçá. Os taxa mais especiosos foram os anelídeos (225 spp.), moluscos (194 spp.), e crustáceos (177 spp.). Entre as espécies bentônicas listadas, sete são endêmicas da Baía do Araçá, 14 são consideradas ameaçadas de extinção, e sete são exploradas economicamente. A baía é a localidade tipo de vários taxa, e 11 novas espécies bentônicas foram descritas com base em espécimes amostrados durante o projeto. Este projeto mostra a importância da Baía do Araçá como um ambiente de riqueza biológica única e demonstra a necessidade de esforços para a sua conservação considerando as atuais ameaças. BIOTAFAPESP BIOTA FAPESP Brasil BIOTAAraçá Paulo praias manguezais rochosos maré ecossistêmicos Infelizmente sócioambientais sócio econômicas i.e. ie i (i.e vs . biodiversidade) área marinho macrofauna meiofauna listados espécie 82 70 225 (22 spp., spp spp. , spp.) 194 (19 177 (17 spp.. listadas 1 extinção economicamente ameaças i.e 8 7 22 (2 19 (1 17 2 (

https://doi.org/10.1590/1676-0611-bn-2023-1583

15.

Periódicos científicos na área Comunicação e Informação: consolidação do índice h e as questões éticas sobre sua utilização Informação
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D'Almonte, Edson Fernando

; Pinho, Fabio Assis

; Oliveira, Thaiane Moreira de

; Santos Junior, Marcelo Alves dos

; Araújo, Ronaldo Ferreira de

; Temer, Ana Carolina Rocha Pessoa

; Marques, Francisco Paulo Jamil

; Bruck, Mozahir Salomão

Em Questão

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2024, Volume 30 elocation e-136673

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Trata-se de uma pesquisa sobre o impacto do uso do índice h na avaliação de periódicos científicos. Mais exatamente, pretende-se verificar a utilização de tais métricas para classificar um conjunto de periódicos brasileiros da área Comunicação e Informação da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. A abordagem metodológica compreende um exame exploratório por meio do qual 20 revistas científicas da área tiveram seus dados extraídos a partir do Google Scholar Metrics no dia 4 de julho de 2022. A coleta também envolveu registro dos metadados de autoria, URL da publicação, periódico, ano e total de citações recebidas. A análise dos dados foi realizada a partir de um cálculo para medida de autocitação do próprio periódico e, em seguida, um periódico teve sua análise destacada. Os resultados demonstraram que duas revistas se destacaram na porcentagem de citação, volume de citações advindo de erros de metadados e falta de metadados estruturados para análise da fonte. Assim sendo, a despeito do índice h ser uma métrica interessante para a avaliação de periódicos na área Comunicação e Informação, considera-se que ela poderia ser complementada por avaliações qualitativas capazes de compreender os desafios éticos necessários para garantir uma avaliação justa e adequada da pesquisa acadêmica. Tratase Trata científicos exatamente pretendese pretende Superior 2 2022 autoria publicação recebidas seguida destacada citação fonte sendo considerase considera acadêmica 202

Abstract This research investigates the impact of using the h-index in the evaluation of scientific journals. Specifically, we aim to assess the use of these metrics to categorize a set of Brazilian journals from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Communication and Information area. The methodological approach involves an exploratory examination in which data from 20 scientific journals in the area were extracted from Google Scholar Metrics on July 4, 2022. The data collection also included recording authorship metadata, publication URL, periodical, year, and the total number of citations received. Data analysis was conducted through a calculation to measure each journal's self-citation, and one journal had its analysis highlighted. The results demonstrated that two journals stood out in terms of citation percentage, the volume of citations resulting from metadata errors, and the lack of structured metadata for source analysis. Therefore, despite the h-index being an interesting metric for evaluating journals in the Communication and Information area, it is considered that it could be complemented by qualitative evaluations capable of understanding the ethical challenges necessary to ensure a fair and adequate evaluation of academic research. hindex h index Specifically 2 4 2022 URL periodical year received s selfcitation, selfcitation self citation, self-citation highlighted percentage errors Therefore 202

https://doi.org/10.1590/1808-5245.30.136673

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