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ABSTRACT Objective To analyze the karyotype test and myeloid panel with next-generation sequencing findings in patients with myelofibrosis, and to compare transplant characteristics in patients referred for bone marrow transplantation. Methods Retrospective, single-center study with patients diagnosed with myelofibrosis treated at Hospital Israelita Albert Einstein between 2010 and 2020. Results A total of 104 patients with myelofibrosis were examined. Patients who had not been submitted to tests in our service were excluded. The final sample comprised 69 patients. Of these 69, 56 were submitted to karyotyping and 22 to myeloid panel with next-generation sequencing. Karyotype was normal in 60% of the patients and altered in 40%. The prevalence of high-risk molecular mutations was higher in patients referred for bone marrow transplantation (100% versus 50%). The median follow-up of transplant patients was 2.4 years and the overall survival at 2 years was 80% (95%CI: 62-100%). Conclusion The molecular analysis enables estimating the patient’s risk and thus instituting more aggressive treatment such as bone marrow transplant for patients at higher risk, being a relevant tool to guide therapy. Given the significance of molecular analysis for therapeutic decision-making in myelofibrosis, collection and disclosure of data on the prevalence of cytogenetic changes and findings of next-generation sequencing in affected patients is important.

https://doi.org/10.31744/einstein_journal/2023ao0100

Contributions of the institutions for the nursing professionalization: integrative review (2010-2020) in the light of freidsonian conceptions
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Maia, Natália Maria Freitas e Silva

; Silva, Francisca Aline Amaral da

; Araújo, Agostinho Antônio Cruz

; Santos, Ana Maria Ribeiro dos

; Santos, Fernanda Batista Oliveira

; Aperibense, Pacita Geovana Gama de Sousa

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 1 elocation e20220153

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Analisar na literatura contribuições da Associação Brasileira de Enfermagem e dos Conselhos Federal e Regionais de Enfermagem para a profissionalização da enfermagem à luz das concepções teóricas de Eliot Freidson. Métodos: Revisão integrativa, de interesse histórico socioprofissional, realizada de junho a novembro de 2021, mediante a questão: Como as entidades de classe contribuíram para a profissionalização da enfermagem brasileira de acordo com a literatura de 2010 a 2020? Organizaram-se as evidências em quadro sinótico, que possibilitou a construção de mapa conceitual. Resultados: Nos 23 estudos selecionados, as entidades de classe apresentaram contribuições científicas, sociais e políticas, que conformam o campo profissional da enfermagem, possibilitando conhecimento/expertise, autonomia e autorregulação. Considerações finais: Os esforços dessas entidades reafirmam a enfermagem como profissão acadêmica e de consulta, capaz de exercer controle sobre a essência do trabalho da enfermagem. Elas se empenham em consolidar a enfermagem como legítimo campo profissional da saúde no Brasil.

ABSTRACT Objective: To analyze the contributions of the Brazilian Nursing Association and the Federal and Regional Nursing Councils in the literature for the professionalization of nursing in the light of Eliot Freidson’s theoretical conceptions. Methods: Integrative review of the literature, of socio-professional historical interest, carried out from June to November 2021, through the question: How did professional associations contribute to the professionalization of Brazilian nursing according to the literature from 2010 to 2020? The evidence were organized in a synoptic table, which allowed the construction of a conceptual map. Results: In the 23 selected studies, the professional associations presented scientific, social and political contributions, which shape the professional field of nursing, enabling knowledge/expertise, autonomy and self-regulation. Final considerations: The efforts of these institutions reaffirm nursing as an academic and consulting profession, capable of exerting control over the essence of nursing work. They strive to consolidate nursing as a legitimate professional field of health in Brazil.

RESUMEN Objetivo: Analizar las contribuciones de la Asociación Brasileña de Enfermería y de los Consejos Federales y Regionales de Enfermería a la profesionalización de la enfermería bajo la luz de las concepciones teóricas de Eliot Freidson Métodos: Se trata de una revisión integradora, de interés histórico socio profesional, realizada de junio a noviembre de 2021, mediante la pregunta: ¿Cómo han contribuido las entidades de clase con la profesionalización de la enfermería brasileña según la literatura de 2010 a 2020? Las pruebas se organizaron en un cuadro sinóptico que permitió construir un mapa conceptual. Resultados: En los 23 estudios seleccionados, las entidades de clase presentaron contribuciones científicas, sociales y políticas, que forman el campo profesional de la enfermería y facilitan el conocimiento, la experticia, la autonomía y la autorregulación. Consideraciones finales: Las entidades reafirman que la enfermería es una profesión académica y de consulta, capaz de ejercer el control sobre la esencia del trabajo en sí y perseveran para consolidarla como un campo profesional legítimo en el Brasil.

https://doi.org/10.1590/0034-7167-2022-0153

Tradução e adaptação para o português da Preterm Infant Breastfeeding Behaviour Scale
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Gomes, Susana de Freitas

; Christoffel, Marialda Moreira

; Gomes, Ana Leticia Monteiro

; Rodrigues, Elisa da Conceição

; Diniz, Maria Estela Machado

; Silveira, Ana Luiza Dorneles da

; Guimarães, Bruna Ribeiro

; Wolf, Marita Gomes de Oliveira

Acta Paulista de Enfermagem

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2023, Volume 36 elocation eAPE00171

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo Traduzir, adaptar culturalmente e validar o conteúdo da Preterm Infant Breastfeeding Behaviour Scale (PIBBS) Métodos Estudo metodológico, cujas etapas foram: tradução inicial; síntese das traduções; retrotradução; revisão das versões traduzidas; validação do conteúdo; pré-teste; e encaminhamento da documentação ao Comitê de Revisão da Adaptação Transcultural. Tanto a escala original quanto a traduzida e adaptada possuem seis itens e cada item contém 03 a 06 subitens com escores de pontuação que variam de 0 a 6. A pontuação total pode variar de 0 a 20. Para a etapa de validação foi realizado o cálculo do índice de validade de conteúdo (IVC) de todos os itens da escala. Foi considerado IVC mínimo de 0,8 como aceitável, para avaliação de cada item individualmente; e de 0,90, para avaliação geral do instrumento. Resultados A versão brasileira da escala PIBBS foi denominada de Escala Comportamental de amamentação do pré-termo. A escala foi traduzida, adaptada e seu conteúdo foi validado, alcançando equivalência conceitual e idiomática que variou de 83,3% a 100%. O índice de validade de conteúdo foi de 0,93. Conclusão Após a tradução, adaptação e validação pelos profissionais de saúde a escala se mostrou válida, de fácil aplicação e linguagem de fácil entendimento. A escala permitirá que os profissionais de saúde possam observar o comportamento do prematuro e orientar a mãe, estimulando assim o aleitamento materno exclusivo, já que o processo de amamentação do prematuro é complexo. Sua utilização em pesquisas futuras e prática clínica permitirá complementar as análises psicométricas mais robustas.

Abstract Objective To translate, culturally adapt and validate the Preterm Infant Breastfeeding Behavior Scale (PIBBS) content Methods This is a methodological study, whose steps were: initial translation; synthesis of translations; back-translation; review of translated versions; content validity; pre-test; and sending the documentation to the Cross-Cultural Adaptation Review Committee. Both the original scale and the translated and adapted scale have six items, and each item contains 03 to 06 sub-items with score scores ranging from 0 to 6. The total score can range from 0 to 20. For the validity step, the Content Validity Index (CVI) of all scale items was calculated. A minimum CVI of 0.8 was considered acceptable for assessing each item individually, and 0.90, for generally assessing the instrument. Results The Brazilian version of PIBBS was called the “Escala Comportamental de Amamentação do Pré-Termo”. The scale was translated, adapted and its content was validated, achieving conceptual and idiomatic equivalence ranging from 83.3% to 100%. The CVI was 0.93. Conclusion After translation, adaptation and validity by health professionals, the scale proved to be valid, easy to apply and easy to understand language. The scale will allow health professionals to observe preterm infants’ behavior and guide mothers, thus encouraging exclusive breastfeeding, since the breastfeeding process of a preterm infant is complex. Its use in future research and clinical practice will complement more robust psychometric analyses.

Resumen Objetivo Traducir, adaptar culturalmente y validar el contenido de la Preterm Infant Breastfeeding Behaviour Scale (PIBBS). Métodos Estudio metodológico, cuyas etapas fueron: traducción inicial, síntesis de las traducciones, retrotraducción, revisión de las versiones traducidas, validación de contenido, prueba piloto y envío de la documentación al Comité de Revisión de Adaptación Transcultural. Tanto la escala original, como la traducida y adaptada, contienen seis ítems y cada uno contiene de tres a seis subítems con puntuación que varía de 0 a 6. La puntuación total puede variar de 0 a 20. Para la etapa de validación se realizó el cálculo de índice de validez de contenido (IVC) de todos los ítems de la escala. Se consideró IVC mínimo de 0,8 como aceptable para la evaluación de cada ítem individualmente, y de 0,90 para la evaluación general del instrumento. Resultados La versión brasileña de la escala PIBBS fue denominada “Escala Comportamental de amamentação do pré-termo” (Escala de Comportamiento de Lactancia del Recién Nacido Prematuro). La escala fue traducida y adaptada, y su contenido fue validado, con una equivalencia conceptual e idiomática que varió de 83,3 % a 100 %. El índice de validez de contenido fue de 0,93. Conclusión Después de su traducción, adaptación y validación por parte de los profesionales de la salud, la escala demostró ser válida, de fácil aplicación y con un lenguaje de fácil comprensión. La escala permitirá que los profesionales de la salud puedan observar el comportamiento del prematuro y orientar a la madre, con el objetivo de estimular la lactancia materna exclusiva, ya que el proceso de lactancia del prematuro es complejo. Su uso en investigaciones futuras y en la práctica clínica permitirá complementar análisis psicométricos más sólidos.

https://doi.org/10.37689/acta-ape/2023ao00171

O que mudou entre os períodos de pico e de platô durante a primeira onda do SARS-CoV-2? Estudo multicêntrico português em unidades de cuidados intensivos
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Pereira, Rui Antunes

; Sousa, Marta

; Cidade, José Pedro

; Melo, Luís

; Lopes, Diogo

; Ventura, Sara

; Aragão, Irene

; Lima Neto, Raul Miguel de Freitas

; Molinos, Elena

; Marques, Ana

; Cardoso, Nelson

; Marino, Flávio

; Monteiro, Filipa Brás

; Oliveira, Ana Pinho

; Silva, Rogério C

; Real, André Miguel Neto

; Banheiro, Bruno Sarmento

; Reis, Renato

; Adão-Serrano, Maria

; Cracium, Ana

; Valadas, Ana

; Ribeiro, João Miguel

; Póvoa, Pedro

; Tapadinhas, Camila

; Mendes, Vítor

; Coelho, Luís

; Maia, Raquel

; Freitas, Paulo Telles

; Ferreira, Isabel Amorim

; Ramires, Tiago

; Val-Flores, Luís Silva

; Cascão, Mariana

; Alves, Rita

; Rodeia, Simão C

; Barrigoto, Cleide

; Cardiga, Rosa

; Silva, Maria João Ferreira da

; Vale, Bruno

; Fonseca, Tatiana

; Rios, Ana Lúcia

; Camões, João

; Pérez, Danay

; Cabral, Susana

; Ribeiro, Maria Inês

; Mendes, João João

; Gouveia, João

; Fernandes, Susana Mendes

Revista Brasileira de Terapia Intensiva

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dec 2022, Volume 34 N. 4 Pages 433 - 442

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar e comparar as características de pacientes críticos com a COVID-19, a abordagem clínica e os resultados entre os períodos de pico e de platô na primeira onda pandêmica em Portugal. Métodos: Este foi um estudo de coorte multicêntrico ambispectivo, que incluiu pacientes consecutivos com a forma grave da COVID-19 entre março e agosto de 2020 de 16 unidades de terapia intensiva portuguesas. Definiram-se as semanas 10 - 16 e 17 - 34 como os períodos de pico e platô. Resultados: Incluíram-se 541 pacientes adultos com mediana de idade de 65 [57 - 74] anos, a maioria do sexo masculino (71,2%). Não houve diferenças significativas na mediana de idade (p = 0,3), no Simplified Acute Physiology Score II (40 versus 39; p = 0,8), na pressão parcial de oxigênio/fração inspirada de oxigênio (139 versus 136; p = 0,6), na terapia com antibióticos na admissão (57% versus 64%; p = 0,2) ou na mortalidade aos 28 dias (24,4% versus 22,8%; p = 0,7) entre o período de pico e platô. Durante o período de pico, os pacientes tiveram menos comorbidades (1 [0 - 3] versus 2 [0 - 5]; p = 0,002); fizeram mais uso de vasopressores (47% versus 36%; p < 0,001) e ventilação mecânica invasiva na admissão (58,1% versus 49,2%; p < 0,001), e tiveram mais prescrição de hidroxicloroquina (59% versus 10%; p < 0,001), lopinavir/ritonavir (41% versus 10%; p < 0,001) e posição prona (45% versus 36%; p = 0,04). Entretanto, durante o platô, observou-se maior uso de cânulas nasais de alto fluxo (5% versus 16%; p < 0,001) na admissão, remdesivir (0,3% versus 15%; p < 0,001) e corticosteroides (29% versus 52%; p < 0,001), além de menor tempo de internação na unidade de terapia intensiva (12 versus 8 dias; p < 0,001). Conclusão: Houve mudanças significativas nas comorbidades dos pacientes, nos tratamentos da unidade de terapia intensiva e no tempo de internação entre os períodos de pico e platô na primeira onda da COVID-19.

ABSTRACT Objective: To analyze and compare COVID-19 patient characteristics, clinical management and outcomes between the peak and plateau periods of the first pandemic wave in Portugal. Methods: This was a multicentric ambispective cohort study including consecutive severe COVID-19 patients between March and August 2020 from 16 Portuguese intensive care units. The peak and plateau periods, respectively, weeks 10 - 16 and 17 - 34, were defined. Results: Five hundred forty-one adult patients with a median age of 65 [57 - 74] years, mostly male (71.2%), were included. There were no significant differences in median age (p = 0.3), Simplified Acute Physiology Score II (40 versus 39; p = 0.8), partial arterial oxygen pressure/fraction of inspired oxygen ratio (139 versus 136; p = 0.6), antibiotic therapy (57% versus 64%; p = 0.2) at admission, or 28-day mortality (24.4% versus 22.8%; p = 0.7) between the peak and plateau periods. During the peak period, patients had fewer comorbidities (1 [0 - 3] versus 2 [0 - 5]; p = 0.002) and presented a higher use of vasopressors (47% versus 36%; p < 0.001) and invasive mechanical ventilation (58.1 versus 49.2%; p < 0.001) at admission, prone positioning (45% versus 36%; p = 0.04), and hydroxychloroquine (59% versus 10%; p < 0.001) and lopinavir/ritonavir (41% versus 10%; p < 0.001) prescriptions. However, a greater use of high-flow nasal cannulas (5% versus 16%, p < 0.001) on admission, remdesivir (0.3% versus 15%; p < 0.001) and corticosteroid (29% versus 52%, p < 0.001) therapy, and a shorter ICU length of stay (12 days versus 8, p < 0.001) were observed during the plateau. Conclusion: There were significant changes in patient comorbidities, intensive care unit therapies and length of stay between the peak and plateau periods of the first COVID-19 wave.

https://doi.org/10.5935/0103-507x.20210037-pt

Prevalence and functional status of children with complex chronic conditions in Brazilian PICUs during the COVID-19 pandemic
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Colleti Junior, José

; Prata-Barbosa, Arnaldo

; Lima-Setta, Fernanda

; Araujo, Orlei Ribeiro de

; Horigoshi, Nelson K.

; Cesar, Regina Grigolli

; Souza, Andreia Aparecida Freitas

; Foronda, Flávia Andrea Krepel

; Almeida, Carlos Gustavo de

; Torreão, Lara de Araujo

; Crestani, Francielly

; Carlotti, Ana Paula de Carvalho Panzeri

; Garcia, Pedro Celiny Ramos

Jornal de Pediatria

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sep 2022, Volume 98 N. 5 Pages 484 - 489

Abstract: En | Text: En | PDF: En

Abstract Objective The proportion of children with complex chronic conditions is increasing in PICUs around the world. We determined the prevalence and functional status of children with complex chronic conditions in Brazilian PICUs during the COVID-19 pandemic. Methods The authors conducted a point prevalence cross-sectional study among fifteen Brazilian PICUs during the COVID-19 pandemic. The authors enrolled all children admitted to the participating PICUs with complex chronic conditions on three different days, four weeks apart, starting on April 4th, 2020. The authors recorded the patient's characteristics and functional status at admission and discharge days. Results During the 3 study days from March to June 2020, the authors enrolled 248 patients admitted to the 15 PICUs; 148 had CCC (prevalence of 59.7%). Patients had a median of 1 acute diagnosis and 2 chronic diagnoses. The use of resources/devices was extensive. The main mode of respiratory support was conventional mechanical ventilation. Most patients had a peripherally inserted central catheter (63.1%), followed by a central venous line (52.5%), and 33.3% had gastrostomy or/and tracheostomy. The functional status score was significantly better at discharge compared to admission day due to the respiratory status improvement. Conclusions The prevalence of children with CCC admitted to the Brazilian PICUs represented 59.7% of patients during the COVID-19 pandemic. The functional status of these children improved during hospitalization, mainly due to the respiratory component.

https://doi.org/10.1016/j.jped.2021.12.004

Tecnologias educacionais para o ensino de história da enfermagem: revisão integrativa
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Maia, Natália Maria Freitas e Silva

; Silva, Francisca Aline Amaral

; Santos, Ana Maria Ribeiro dos

; Andrade, Elaine Maria Leite Rangel

; Santos, Fernanda Batista Oliveira

; Araújo, Agostinho Antônio Cruz

Acta Paulista de Enfermagem

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2022, Volume 35 elocation eAPE03017

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo Analizar en la literatura las tecnologías educativas para la enseñanza de historia de la enfermería. Métodos Revisión integradora, con búsqueda y selección en: CINAHL, MEDLINE vía PubMed®, Web of Science, SCOPUS, LILACS y BDENF, vía BVS. Se incluyeron siete estudios publicados en portugués, inglés o español y sin recorte temporal. El análisis fue realizado de forma descriptiva y se relacionaron dos categorías temáticas: las tecnologías digitales y las no digitales para la enseñanza de la historia de la enfermería. Resultados En los estudios se identificaron tecnologías digitales, como páginas web, objeto y ambiente virtual de aprendizaje y no digitales, como series de televisión, literatura de cordel y textos impresos. Hubo un creciente interés de los investigadores por la implementación de tecnologías para la enseñanza y el aprendizaje de la historia de la enfermería, lo que se expresa por el aumento del número de producciones en los últimos 10 años. Conclusión Las tecnologías educativas digitales y no digitales contribuyen para la enseñanza de historia de la enfermería, porque son recursos válidos, seguros, efectivos, atractivos y motivacionales para el aprendizaje activo, así como para el desarrollo de la capacidad crítica y reflexiva en la conformación identitaria.

Abstract Objective To analyze the literature in educational technologies for teaching nursing history. Methods Integrative review of the literature, with search and selection in CINAHL, MEDLINE via PubMed®, Web of Science, SCOPUS, LILACS, and BDENF via VHL. Seven studies published in Portuguese, English, and Spanish without a time frame were included. We descriptively proceeded with the analysis, and we organized two thematic categories: the digital and non-digital technologies for teaching nursing history. Results In the studies, we identified digital technologies, such as websites, virtual learning environments and objects, and non-digital, such as television series, Cordel literature, and printed texts. There was an increasing interest of researchers in the implantation of technologies for teaching nursing history, expressed by the increase in the number of studies in the last ten years. Conclusion Digital and non-digital educational technologies contributed to nursing history teaching by being valid, safe, effective, attractive, and motivational for active learning, as well as for the development of the critical and reflective ability in the identity conformation.

Resumo Objetivo Analisar na literatura as tecnologias educacionais para o ensino de história da enfermagem. Métodos Revisão integrativa, com busca e seleção em: CINAHL, MEDLINE via PubMed®, Web of Science, SCOPUS, LILACS e BDENF, via BVS. Sete estudos publicados em português, inglês ou espanhol e sem recorte temporal foram incluídos. A análise foi procedida de forma descritiva e duas categorias temáticas foram elencadas: as tecnologias digitais e não digitais para o ensino de história da enfermagem. Resultados Nos estudos, identificaram-se tecnologias digitais, como sites, objeto e ambiente virtual de aprendizagem e não digitais, como séries de televisão, literatura de cordel e textos impressos. Houve crescente interesse de pesquisadores pela implementação de tecnologias para o ensino e a aprendizagem da história da enfermagem, sendo expresso pelo aumento do número de produções nos últimos 10 anos. Conclusão As tecnologias educacionais digitais e não digitais contribuem para o ensino de história da enfermagem, por serem recursos válidos, seguros, efetivos, atrativos e motivacionais para a aprendizagem ativa, assim como para o desenvolvimento da capacidade crítica e reflexiva na conformação identitária.

https://doi.org/10.37689/acta-ape/2022ar0003017

Análise espacial da taxa de detecção de casos suspeitos de síndrome congênita pelo vírus Zika, Maranhão, 2015 a 2018
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Falcão Neto, Paulo Afonso de Oliveira

; Branco, Maria dos Remédios Freitas Carvalho

; Costa, Silmery da Silva Brito

; Câmara, Ana Patrícia Barros

; Marques, Thayná Millena Nunes França

; Araujo, Adriana Soraya

; Loureiro, Flávia Helen Furtado

; Dias Júnior, José de Jesus

; Silva, Maria do Socorro da

; Queiroz, Rejane Christine de Sousa

; Ribeiro, Marizélia Rodrigues Costa

; Kulkarni, Manisha Ann

; Silva, Antônio Augusto Moura da

; Santos, Alcione Miranda dos

Revista Brasileira de Epidemiologia

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2022, Volume 25 elocation e220002

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Objetivo: Identificar padrões espaciais em casos de lactentes com alterações de crescimento e desenvolvimento relacionadas à infecção pelo vírus Zika e outras etiologias infecciosas (neste trabalho denominado de síndrome congênita pelo vírus Zika), notificados no Maranhão de 2015 a 2018 e sua relação com variáveis socioeconômicas e demográficas. Métodos: Estudo ecológico de casos suspeitos notificados de síndrome congênita pelo vírus Zika nos 217 municípios do Maranhão, Brasil. Calculou-se a autocorrelação espacial pelos índices de Moran local e global (I) univariado e bivariado da taxa de detecção de casos suspeitos de síndrome congênita pelo vírus Zika com índice de desenvolvimento humano municipal, densidade demográfica, índice de Gini e tempo de emancipação político-administrativa dos municípios. O índice de Moran local foi calculado para localizar clusters com autocorrelação espacial significativa. Resultados: Houve autocorrelação espacial na análise univariada da taxa municipal de detecção de casos suspeitos de síndrome congênita pelo vírus Zika (I=0,494; p=0,001) e, na análise bivariada, correlação positiva da taxa de detecção de casos suspeitos com índice de desenvolvimento humano municipal (I=0,252; p=0,001), densidade demográfica (I=0,338; p=0,001) e tempo de emancipação dos municípios (I=0,134; p=0,001). Não houve correlação significativa da taxa de detecção de casos suspeitos com o índice de Gini (I= -0,033; p=0,131). Cinco clusters de alta detecção de casos suspeitos foram encontrados em áreas distintas do estado. Conclusões: Os municípios com maior índice de desenvolvimento humano municipal, maior densidade demográfica e mais tempo de emancipação político-administrativa tiveram mais casos suspeitos notificados de síndrome congênita pelo vírus Zika.

ABSTRACT: Objective: To identify spatial patterns in cases of changes in growth and development related to Zika virus infection and other infectious etiologies (denominated Zika virus congenital syndrome in this study) reported in Maranhão from 2015 to 2018 and their relation with socioeconomic and demographic variables. Methods: Ecological study of notified Zika virus congenital syndrome cases in the 217 cities of Maranhão, Brasil. Spatial autocorrelation was calculated using GeoDa 1.14 software and the local and global (I) Moran’s index in univariate and bivariate analyses on Zika virus congenital syndrome incidence rate with Municipal Human Development Index (MHDI), population density, Gini coefficient and the cities’ time of administrative political emancipation. Local Moran’s Index was calculated to identify clusters with significant spatial autocorrelation. Results: Spatial autocorrelation was checked in univariate analysis of the incidence rate of Zika virus congenital syndrome (I=0,494; p=0,001) and positive correlation in bivariate analysis of the incidence rate with Municipal Human Development Index (I=0,252; p=0,001), population density (I=0,338; p=0,001) and the cities’ time of administrative political emancipation (I=0,134; p=0,001). The correlation between incidence rate with Gini coefficient was not significant (I= -0,033; p=0,131). Five high-incidence clusters were found in distinct areas of the state. Conclusions: Cities with higher MHDI, higher population density and more years of administrative political emancipation had more cases of Zika virus congenital syndrome notified.

https://doi.org/10.1590/1980-549720220002

Análise espacial da taxa de detecção de casos suspeitos de síndrome congênita pelo vírus Zika, Maranhão, 2015 a 2018
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Falcão Neto, Paulo Afonso de Oliveira

; Branco, Maria dos Remédios Freitas Carvalho

; Costa, Silmery da Silva Brito

; Câmara, Ana Patrícia Barros

; Marques, Thayná Millena Nunes França

; Araujo, Adriana Soraya

; Loureiro, Flávia Helen Furtado

; Dias Júnior, José de Jesus

; Silva, Maria do Socorro da

; Queiroz, Rejane Christine de Sousa

; Ribeiro, Marizélia Rodrigues Costa

; Kulkarni, Manisha Ann

; Silva, Antônio Augusto Moura da

; Santos, Alcione Miranda dos

Revista Brasileira de Epidemiologia

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2022, Volume 25 elocation e220002

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720220002

Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT)
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Falavigna, Maicon

; Belli, Karlyse Claudino

; Barbosa, Alexandre Naime

; Zavascki, Alexandre Prehn

; Nastri, Ana Catharina de Seixas Santos

; Santana, Christiane Machado

; Stein, Cinara

; Gräf, Débora Dalmas

; Cadegiani, Flavio Adsuara

; Guimarães, Hélio Penna

; Monteiro, José Tadeu

; Ferreira, Juliana Carvalho

; de Azevedo, Luciano Cesar Pontes

; Magri, Marcelo Mihailenko Chaves

; Sobreira, Marcone Lima

; Dias, Maria Beatriz Gandra de Souza

; de Oliveira, Maura Salaroli

; Corradi, Mirian de Freitas Dal Ben

; Rosa, Regis

; Heinzelmann, Ricardo Souza

; da Silva, Rosemeri Maurici

; Belfort Junior, Rubens

; Cimerman, Sergio

; Colpani, Verônica

; Veiga, Viviane Cordeiro

; de Carvalho, Carlos Roberto Ribeiro

Brazilian Journal of Infectious Diseases

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2022, Volume 26 N. 2 elocation 102347

Abstract: En | Text: En | PDF: En

ABSTRACT Background Several therapies have been used or proposed for the treatment of COVID-19, although their effectiveness and safety have not been properly evaluated. The purpose of this document is to provide recommendations to support decisions about the drug treatment of outpatients with COVID-19 in Brazil. Methods A panel consisting of experts from different clinical fields, representatives of the Brazilian Ministry of Health, and methodologists (37 members in total) was responsible for preparing these guidelines. A rapid guideline development method was used, based on the adoption and/or adaptation of recommendations from existing international guidelines combined with additional structured searches for primary studies and new recommendations whenever necessary (GRADE-ADOLOPMENT). The rating of quality of evidence and the drafting of recommendations followed the GRADE method. Results Ten technologies were evaluated, and 10 recommendations were prepared. Recommendations were made against the use of anticoagulants, azithromycin, budesonide, colchicine, corticosteroids, hydroxychloroquine/chloroquine alone or combined with azithromycin, ivermectin, nitazoxanide, and convalescent plasma. It was not possible to make a recommendation regarding the use of monoclonal antibodies in outpatients, as their benefit is uncertain and their cost is high, with limitations of availability and implementation. Conclusion To date, few therapies have demonstrated effectiveness in the treatment of outpatients with COVID-19. Recommendations are restricted to what should not be used, in order to provide the best treatment according to the principles of evidence-based medicine and to promote resource savings by aboiding ineffective treatments.

https://doi.org/10.1016/j.bjid.2022.102347

10.

Solar drying of 'Prata' bananas
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SILVA, Álvaro Gustavo Ferreira da

; CRUZ, Renata Ranielly Pedroza

; MOREIRA, Wennia Gomes

; PEREIRA, Maria Angelica Freitas

; SILVA, Adriano Sant'Ana

; COSTA, Franciscleudo Bezerra da

; NASCIMENTO, Ana Marinho do

; SOUZA, Pahlevi Augusto de

; TIMOTEO, André Luiz dos Santos

; RIBEIRO, Wellington Souto

Food Science and Technology

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2022, Volume 42 elocation e75021

Abstract: En | Text: En | PDF: En

Abstract The banana is one of the most consumed fruits in the world, but it has little shelf life due to its high water activity. Drying is able to increase shelf life and pre-treatments can optimize the process. The objective was to study the solar drying kinetics and evaluate the effect of pre-treatments on the drying kinetics and physico-chemical quality of 'Prata' bananas. The drying was carried out in a solar dryer and the pre-treatments consisted of immersing the samples in solutions of water, citric acid (1%) and lemon juice (10%). Water loss, drying kinetics, mathematical models and physical-chemical and colorimetric characteristics of fresh and dried bananas were evaluated. The drying rate was higher at the beginning and stabilized after 20 hours. The mathematical model of Midilli and Kucuk was the one that best fit the experimental data. The water content, ascorbic acid and the parameters L *, b *, C * and h ° reduced after drying. Reducing sugars and a * coordinate increased and the acidity was not changed with drying. The solar drying of 'Prata' bananas is a sustainable and economical way to make a product available with a longer shelf life.

https://doi.org/10.1590/fst.75021

11.

Maternal Mortality in Brazil, 1990 to 2019: a systematic analysis of the Global Burden of Disease Study 2019
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Leal, Lisiane Freitas

; Malta, Deborah Carvalho

; Souza, Maria de Fatima Marinho

; Vasconcelos, Ana Maria Nogales

; Teixeira, Renato Azeredo

; Veloso, Guilherme Augusto

; Lansky, Sônia

; Ribeiro, Antonio Luiz Pinho

; França, Giovanny Vinícius Araújo de

; Naghavi, Mohsen

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 Suppl. 1 elocation e0279-2021

Abstract: En | Text: En | PDF: En

Abstract INTRODUCTION Maternal death continues to be one of the most challenging public health problems that needs to be addressed in low and middle-income countries. The objective of this study was to describe the problem of maternal death in Brazil, using estimates from the Global Burden of Disease Study (GBD). METHODS This study used data from the GBD 2019 to show the numbers of deaths and the Maternal Mortality Ratio (MMR) - number of deaths/100,000 live births - in Brazil and its 27 Federated Units (FU), for ages 10 to 54 years, from 1990 to 2019. The annual variation of the MMR was estimated in 1990, 2010, and 2019. The MMR were shown for specific causes as well as for five-year age groups. The estimates were presented with 95% uncertainty intervals (UI). RESULTS The number of maternal deaths, as well as the MMR showed a 49% reduction from 1990 to 2019. This reduction occurred heterogeneously throughout the country, and the profile of the MMR for specific causes changed between 1990 and 2019: from hypertensive gestation diseases, to indirect maternal deaths, followed by hypertensive gestation diseases. In the extreme age groups, the MMR is higher, with mortality increasing exponentially in direct proportion with age. CONCLUSIONS Maternal deaths in Brazil have decreased substantially since 1990; however, the numbers still fall short of what was established by the World Health Organization (WHO). Indirect causes are the greatest problem in more than 60% of the FU, especially for hypertensive pregnancy diseases.

https://doi.org/10.1590/0037-8682-0279-2021

12.

Tecnologias educacionais para o ensino de história da enfermagem: revisão integrativa
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Maia, Natália Maria Freitas e Silva

; Silva, Francisca Aline Amaral

; Santos, Ana Maria Ribeiro dos

; Andrade, Elaine Maria Leite Rangel

; Santos, Fernanda Batista Oliveira

; Araújo, Agostinho Antônio Cruz

Acta Paulista de Enfermagem

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2022, Volume 35 elocation eAPE03017

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.37689/acta-ape/2022ar0003017

13.

Scenario validation for clinical simulation: prenatal nursing consultation for adolescents
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Nascimento, Fernanda Coêlho do

; Araújo, Ana Paula de Freitas

; Viduedo, Alecssandra de Fátima Silva

; Ribeiro, Laiane Medeiros

; Leon, Casandra Genoveva Rosales Martins Ponce de

; Schardosim, Juliana Machado

Revista Brasileira de Enfermagem

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2022, Volume 75 N. 3 elocation e20200791

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: validar um cenário para simulação clínica, no ensino de enfermagem, sobre primeira consulta de pré-natal à gestante adolescente. Métodos: estudo metodológico desenvolvido de janeiro a dezembro de 2019, em cinco etapas (overview, scenario, scenario design progression, debriefing e assessment). A validação envolveu quatro alunos voluntários, uma docente como facilitadora e quatro juízes. Os juízes preencheram uma escala Likert com quatro respostas. Os dados foram analisados no software Microsoft Excel®, versão 2016. Calcularam-se as frequências absolutas e relativas e o índice de validade de conteúdo, considerando valor mínimo aceitável de 1,0. Resultados: a elaboração do cenário partiu dos objetivos de aprendizagem propostos. O cenário foi validado com índice de validade de conteúdo global igual a 1,0. Considerações Finais: o estudo alcançou o objetivo proposto. Este cenário pode contribuir para preparar enfermeiros para atuação na atenção às gestantes adolescentes, um público representativo no Brasil e que requer cuidados específicos.

ABSTRACT Objectives: to validate a scenario for clinical simulation: prenatal nursing consultation for adolescents. Methods: methodological study developed from January to December 2019, in five stages (overview, scenario, scenario design, progression, debriefing and assessment). The validation involved four volunteer students, a teacher as a facilitator and four judges. The judges filled out a Likert scale with four responses. Data was analyzed using Microsoft Excel® software, version 2016. Absolute and relative frequencies and the content validity index were calculated, considering a minimum acceptable value of 1.0. Results: the preparation of the scenario was based on the proposed learning objectives. The scenario was validated with a global content validity index equal to 1.0. Final Considerations: the study achieved the proposed objective. This scenario can contribute to preparing nurses to work in the care of pregnant teenagers, a representative public in Brazil that requires specific care.

RESUMEN Objetivos: validar un escenario para simulado clínico, en enseñanza de enfermería, sobre primera consulta de prenatal a gestante adolescente. Métodos: estudio metodológico desarrollado de enero a diciembre de 2019, en cinco etapas (overview, scenario, scenario design progression, debriefing y assessment). La validación involucró cuatro alumnos voluntarios, una docente como facilitadora y cuatro jueces. Los jueces rellenaron una escala Likert con cuatro respuestas. Datos fueran analizados en el software Microsoft Excel®, versión 2016. Calculadas las frecuencias absolutas y relativas y el índice de validez de contenido, considerando valor mínimo aceptable de 1,0. Resultados: la elaboración del escenario partió de los objetivos de aprendizaje propuestos. El escenario fue validado con índice de validez de contenido global igual a 1,0. Consideraciones Finales: el estudio alcanzó el objetivo propuesto. Este escenario puede contribuir para preparar enfermeros para actuación en la atención a gestantes adolescentes, un público representativo en Brasil y que requiere cuidados específicos.

https://doi.org/10.1590/0034-7167-2020-0791

14.

Impactos da pandemia de COVID-19 sobre a saúde mental de profissionais de enfermagem
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Nascimento, Ana Karoline de Freitas

; Barbosa, Yaritsa Milena Martins

; Camargo, Sara Rafaela Valcacio

; Souza, Talita Araujo de

; Gomes, Sávio Marcelino

; Galvão, Maria Helena Rodrigues

; Medeiros, Arthur de Almeida

; Barbosa, Isabelle Ribeiro

Revista Portuguesa de Enfermagem de Saúde Mental

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dec 2021, N. 26 Pages 169 - 186

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Resumen Introducción: A pandemia da COVID-19 apresenta uma maior demanda de trabalho para os profissionais de saúde, em especial, os de enfermagem, por compor a maior parcela entre os trabalhadores de saúde y pelo cuidado prolongado com o paciente. Objetivo: Evaluar los impactos de la pandemia COVID-19 en la salud mental de los profesionales de enfermeira. Metodología: Se trata de un estudio transversal realizado con datos de una encuesta basada en la web que contó con la participación de 490 profesionales de enfermería que laboran en los servicios de mediana y alta complejidad del estado de Rio Grande do Norte, Brasil. El resultado del estudio “impacto de COVID-19 entre profesionales de enfermería” se categorizó con base en el análisis de conglomerados, y luego se realizó un análisis de regresión de Poisson con varianza robusta para estimar la razón de prevalencia del resultado en relación con las variables independientes. Resultados: Os mais impactados apresentaram maior prevalência de Síndrome de Burnout (RP=1,50; p=0,007), sintomas graves de ansiedade (RP=1,36; p=0,019) e depressão (RP=1,40, p=0,011). Conclusión: Una pandemia de COVID-19 impacta directamente en la salud mental dos profesionales de enfermam que atuam na linha de frente, con el desenvolvimiento del Síndrome de Burnout y de síntomas graves de ansiedade e depressão.

Resumo Introdução: A pandemia da COVID-19 apresenta uma maior demanda de trabalho para os profissionais de enfermagem, por compor a maior parcela entre os trabalhadores de saúde e pelo cuidado prolongado com o paciente. Objetivo: Avaliar os impactos da pandemia de COVID-19 na saúde mental de profissionais de enfermagem. Metodologia: Trata-se de um estudo transversal realizado com os dados de um web-based survey que contou com a participação de 490 profissionais de enfermagem atuantes nos serviços de média e alta complexidade do estado do Rio Grande do Norte, Brasil. O desfecho do estudo “impacto da COVID-19 entre os profissionais de enfermagem” foi categorizado a partir da análise de cluster, e em seguida procedeu-se análise de regressão de Poisson com variância robusta para estimar a razão de prevalência do desfecho em relação às variáveis independentes. Resultados: Os mais impactados apresentaram maior prevalência de Síndrome de Burnout (RP=1,50; p=0,007), sintomas graves de ansiedade (RP=1,36; p=0,019) e depressão (RP=1,40, p=0,011). Conclusão: A pandemia de COVID-19 impactou diretamente na saúde mental dos profissionais de enfermagem que atuam na linha de frente, com o desenvolvimento de Síndrome de Burnout e de sintomas graves de ansiedade e depressão.

Abstract Introduction: A COVID-19 pandemic presents a greater demand for work for health professionals, especially those for illnesses, due to a larger share between health workers and long-term care as a patient. Objective: Assess the impacts of the COVID-19 pandemic on the mental health of nursing professionals. Methodology: This is a cross-sectional study carried out with data from a web-based survey that included the participation of 490 nursing professionals working in the medium and high complexity services of the state of Rio Grande do Norte, Brazil. The outcome of the study “impact of COVID-19 among nursing professionals” was categorized based on the cluster analysis, and Poisson regression analysis with robust variance was then performed to estimate the outcome prevalence ratio in relation to the independent variables. Results: The more impacted have a higher prevalence of Burnout Syndrome (PR = 1.50; p = 0.007), severe symptoms of anxiety (PR = 1.36; p = 0.019) and depression (PR = 1.40, p = 0.011). Conclusion: A COVID-19 pandemic directly impacted on mental health two disease professionals who face the front line, as the development of Burnout Syndrome and severe symptoms of anxiety and depression.

https://doi.org/10.19131/rpesm.317 205 downloads

15.

Lignin-modified road marking paint: weathering aging studies
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Pereira, Amanda Petronilha

; Ribeiro, Júlia Lopes

; Oliveira, Ana Carolina Ferreira

; Vasconcelos, Claudia Karina Barbosa

; Viana, Marcelo Machado

; Lins, Vanessa de Freitas Cunha

REM - International Engineering Journal

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jun 2021, Volume 74 N. 2 Pages 225 - 233

Abstract: En | Text: En | PDF: En

Abstract The accelerated artificial aging with ultraviolet radiation, viscosity, density, no-pick-up time, flexibility, and abrasion resistance of lignin-modified road marking paint were evaluated. The addition of lignin did not cause significant changes in the physical chemistry, flexibility and no-pick-time test compared to the precursor paint. The addition of 1.00 wt. % of lignin increased the abrasion resistance by 36%. The Fourier Transform Infrared technique performed before and after exposure to Weather-o-meter aging chamber has shown the cleavage of ester groups that are present in acrylic-based resin. The incorporation of 0.10 wt.%, 0.25 wt.%, and 1.00 wt.% increased the photodegradation resistance of the road marking paint inhibiting the ester group and side-chain scissions, since the C-O and C=O band intensity increased after irradiation. The introduction of lignin delayed the yellowing of the aged samples and improved mechanical and photophysical properties besides being a good strategy for the biomass waste utilization of the paper industry.

https://doi.org/10.1590/0370-44672020740113

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