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au:Rego, C. G. do

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Pesticide Determination in Fresh Coconut Water (Cocos nucifera Linn.) by GC-MS Using Microwave-Assisted Liquid-Liquid Extraction
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Nakamura, Thamilin C.

; Rego, Enoc L. do

; Souza, Jurandir R. de

; Diniz, Paulo H. G. D.

; Silva, José D. S. da

Journal of the Brazilian Chemical Society

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nov 2023, Volume 34 N. 11 Pages 1707 - 1716

Abstract: En | Text: En | PDF: En

Fresh coconut (Cocos nucifera) water, a popular beverage in tropical countries, is often exposed to pesticide contamination due to agricultural practices. Thus, this work proposed the simultaneous determination of 36 pesticides in fresh coconut water samples using liquid-liquid extraction, drying assisted by a household microwave oven, and gas chromatography-mass spectrometry (GC-MS) analysis. Limits of detection varied from 5.4 (disulfoton) to 9.6 ng L-1 (parathion-methyl). Nine pesticide residues were detected (dimethoate, γ-HCH, β-HCH, 4,4’-dichlorodiphenyldichloroethylene, endosulfan II, 4,4’-dichlorodiphenyldichloroethane, 4,4’-dichlorodiphenyltrichloroethane, endrin ketone, and methoxychlor) with concentrations from < limit of quantification to 5,768.34 ± 1.64 ng L-1. Dimethoate was quantified in all samples, indicating its recent use. The proposed methodology offers several advantages, including the use of small sample volumes and solvent extraction, which eliminates the need for costly cartridges and reduces waste production. Additionally, the obtained results can be valuable for regulatory agencies, aiding in the mitigation of environmental damage and the protection of human health.

https://doi.org/10.21577/0103-5053.20230125

A Modified Radiopropagation Multipath Model for Constant Refractivity Gradient Profiles
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Parada, D.

; Rego, C. G.

; Guevara, D.

; Navarro, A.

; Ramos, G. L.

; Oliveira, R.

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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jun 2023, Volume 22 N. 2 Pages 298 - 312

Abstract: En | Text: En | PDF: En

Abstract This paper presents a radiopropagation algorithm based on a Ray Tracing (RT) technique that combines a modified multipath model for constant refractivity gradient profiles and the Uniform Theory of Diffraction (UTD). A novel formulation is proposed by the authors for calculation and ground-reflection analysis of ray paths depending on atmospheric refractivity. The algorithm introduced herein was evaluated in a mixed scenario and in two more realistic case studies, under conditions of constant refractivity gradient and lossy terrain profiles. Pathloss results are obtained and compared with Parabolic Equation (PE) numerical solution results at 2.0 GHz, 3.5 GHz and 5.4 GHz. In such conditions, the modified radiopropagation multipath algorithm with atmospheric refractivity introduced herein showed satisfactory results.

https://doi.org/10.1590/2179-10742023v22i2272846

Evaluation of the antinociceptive effect generated by citronellal monoterpene isomers
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Costa, A. O. C.

; Rego, R. I. A.

; Andrade, H. H. N.

; Costa, T. K. V. L.

; Salvadori, M. G. S. S.

; Almeida, R. N.

; Castro, R. D.

Brazilian Journal of Biology

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2023, Volume 83 elocation e271781

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Due to the complex nature of pain and the participation of physical, cognitive, psychological and behavioral aspects, pain management has several approaches. The use of medicinal plants in developing countries is quite expressive. Seeking new options for the treatment of emerging or debilitating diseases. Therefore, the present study seeks to elucidate the effects of the monoterpene, citronellal, differentiating its activity by isomers (R)-(+) and (S)-(-) citronellal. The study used several methods to evaluate the effects of citronellal isomers on motor coordination, nociceptive response, and the involvement of opioid, glutamatergic, and transient receptor pathways. The methods included rota-rod, hot-plate, and formalin tests, as well as the use of specific inhibitors and agonists. Data were analyzed using inferential statistics with a 95% confidence level. Both isomers did not significantly affect the motor coordination of the studied animals. The isomer (S)-(-) citronellal showed better results in relation to its structural counterpart, managing to have an antinociceptive effect in the formalin and hot plate tests with a lower concentration (100 mg/kg) and presenting fewer side effects, however, the this study was not able to elucidate the mechanism of action of this isomer despite having activity in studies with substances that act on specific targets such as glutamate and capsaicin, its activity was not reversed with the use of antagonists for pathways related to nociception. While the (R)-(+) citronellal isomer, despite showing total activity only at a concentration of 150 mg/kg, was able to determine its mechanism of action related to the opioid pathway by reversing its activity by the antagonist naloxone, being this is a pathway already correlated with nociception control treatments, however, it is also related to some unwanted side effects. In this way, new studies are sought to elucidate the mechanism related to the isomer (S)-(-) citronellal and a possibility of use in other areas related to the treatment of pain or inflammation.

Resumo Devido à natureza complexa da dor e a sua participação de aspectos físicos, cognitivos, psicológicos e comportamentais, o manejo da dor possui diversas abordagens. O uso de plantas medicinais em países em desenvolvimento é bastante expressivo. Buscando novas opções para o tratamento de denças emergentes ou debilitantes. Portanto, o presente estudo busca elucidar os efeitos do monoterpeno, citronelal, diferenciando sua atividade pelos isômeros (R)-(+) e (S)-(-) citronelal. O estudo utilizou diversos métodos para avaliar os efeitos dos isômeros de citronelal na coordenação motora, resposta nociceptiva e o envolvimento de vias opioides, glutamatérgicas e de receptores transitórios. Os métodos incluíram testes de rota-rod, placa quente e formalina, além do uso de inibidores e agonistas específicos. Os dados foram analisados estatisticamente com um intervalo de confiança de 95%. Ambos os isomeros não afetaram significativamente a coordenação motora dos animais em estudo. O isômero (S)-(-) citronelal apresentou melhores resultados em relação ao seu homólogo estrutural, conseguindo ter um efeito antinociceptivo nos testes de formalina e placa quente com menor concentração (100 mg/kg) e apresentando menos efeitos colaterais, entretanto, o presente estudo não foi capaz de elucidar o mecanismo de ação deste isomero apesar de ter atividadade em estudos com substancias que agem em alvos específicos como glutamato e capsaicina, sua atividade não foi revertida com a utilização de antagonistas para as vias relacionadas à nocicepção. Enquanto o isômero (R)-(+) citronelal, apesar de apresentar de apresentar total atividade somente na concentração de 150 mg/kg, foi capaz de determinar seu mecanismo de ação relacionado à via opióide pela reversão da sua atividade pelo antagonista naloxona, sendo esta uma via já correlacionada com os tratamentos de controle da a nocicepção, no entanto, também está relacionada a alguns efeitos colaterais indesejados. Desta forma busca-se novos estudos para elucidação do mecanismo relacionados ao isomero (S)-(-) citronellal e uma possibilidade de utilização em outras areas relacionadas ao tratamento da dor ou inflamação.

https://doi.org/10.1590/1519-6984.271781

Ternary system Portland cement-calcium aluminate cement-calcium sulfate applied to self-leveling mortar: a literature review
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Rego, A. C. A.

; Cardoso, F. A.

; Pileggi, R. G.

Cerâmica

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mar 2021, Volume 67 N. 381 Pages 65 - 82

Abstract: En | Text: En | PDF: En

Abstract The modernization of building systems is increasingly demanding products that improve efficiency during their processing. The development of self-leveling mortars for the regularization of flooring is a consequence of this evolution. The high contents of binder and water to obtain self-flowing property, plus the application of thin layers over large areas, make this type of mortar susceptible to high shrinkage levels. Thus, the ternary system Portland cement-calcium aluminate cement-calcium sulfate (OPC-CAC-CaSO4) is a viable solution for shrinkage compensation. The expansion mechanism based on ettringite formation aims to prevent the mortar from cracking. Considering its complexity and that international literature is still limited (while Brazilian is null), this article presents a literature review that covers diverse aspects related to the application of the system OPC-CAC-CaSO4. The influence of raw materials and mix proportions on rheological behavior, reaction kinetics, development of strength, and length change are discussed.

https://doi.org/10.1590/0366-69132021673812929 814 downloads

Cytotoxicity and Leishmanicidal Activity of Isoniazid-Derived Hydrazones and 2-Pyrazineformamide Thiosemicarbazones
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Amim, Raquel S.

; Firmino, Gisele S. S.

; Rego, Ana C. P. D.

; Nery, Adriane L.

; Da-Silva, Silvia A. G.

; Souza, Marcus V. N. de

; Pessoa, Claudia

; Resende, Jackson A. L. C.

; Figueroa-Villar, José D.

; Lessa, Josane A.

Journal of the Brazilian Chemical Society

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apr 2016, Volume 27 N. 4 Pages 769 - 777

Abstract: En | Text: En | PDF: En

The isoniazid-derived hydrazones 2-pyridinecarbaldehyde- (HPCIH), 2-acetylpyridine- (HAPIH), 2-benzoylpyridine- (HBPIH), 2-pyridineformamide- (HPAmIH) and 2-pyrazineformamide- (HPzAmIH) isonicotinoyl hydrazones, as well as the pyrazinamide-derived thiosemicarbazones 2-pyrazineformamide- (HPzAm4DH), N(4)-methyl-2-pyrazineformamide- (HPzAm4M), N(4)-ethyl-2-pyrazineformamide- (HPzAm4E) and N(4)-phenyl-2-pyrazineformamide- (HPzAm4Ph) thiosemicarbazones, were assayed for their action against intracellular amastigote form of Leishmania (Viannia) braziliensis strains and the glioblastoma multiforme (SF-295), colon adenocarcinoma (HCT-116), ovarian cancer (OVCAR-8) and acute myeloid leukemia (HL-60) human tumor cell lines. All compounds exhibited leishmanicidal effects, with concentrations at which 50% of parasites were inhibited (IC50) in the 10.70-18.84 µM range. Moreover, the compounds were up to 30-fold less toxic to macrophages than to the parasites. Pyrazinamide-derived thiosemicarbazones proved to have poor activity against the tumor cell lines at 5 µg mL-1, whereas, in general the isoniazid-derived hydrazones presented good activity, being HAPIH and HBPIH the most potent compounds (IC50 = 0.42-1.5 µM).

https://doi.org/10.5935/0103-5053.20150330 1249 downloads

Semi-analytical formulation for a Unified Time and Frequency Antenna Characterization
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Gonçalves, S. T. M

; Rego, C. G. do

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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jun 2015, Volume 14 N. 1 Pages 83 - 96

Abstract: En | Text: En | PDF: En

AbstractThe definition of parameters that characterize the radiation of electric and magnetic fields for antennas in the time and frequency domain on an unified representation is proposed. The formulation uses a straightforward semi-analytical formulation that can be subsequently applied on the analysis of excited antennas for an arbitrary source with temporal behavior. The effective height is a parameter for antenna analysis defined for quantities in far field region and can be used as a transfer function of the antenna. This transfer function can be described through the antenna singularities which can be obtained by singularity expansion. The Singularity Expansion Method (SEM) is capable to model an electromagnetic quantity with the singularities extracted by the current densities of an arbitrary object. This work proposes that the singularities are extracted by the Matrix Pencil method applied on the current densities. The current densities are obtained numerically through the method of the Finite Differences in the Time Domain (FDTD) for wired log-periodic antenna and, after the singularities are obtained, the formulation of the semi-analytical effective height equation is written. To validate the presented method, a formulation of the time-domain radiation pattern is presented and a corresponding frequency-domain radiation pattern is also presented using Parseval’s theorem.

https://doi.org/10.1590/2179-10742015v14i1429 920 downloads

Determination of Aldrin Purity Using a Combination of the Mass Balance Approach and Quantitative NMR
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Rodrigues, Janaína M.

; Rego, Eliane C. P.

; Guimarães, Evelyn F.

; Sousa, Marcus V. B.

; Monteiro, Tânia M.

; Neves, Laura A.

; Violante, Fernando G. M.

; Almeida, Renato R. R.

; Quaresma, Maria C. B.

; Nogueira, Raquel

Journal of the Brazilian Chemical Society

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may 2015, Volume 26 N. 5 Pages 869 - 879

Abstract: En | Text: En | PDF: En

This paper describes the studies performed to determine the purity of aldrin samples, an organochlorine pesticide, using the mass balance approach. The organic impurities were identified and quantified by gas chromatography-mass spectrometry (GC-MS), gas chromatography with flame ionization detection (GC-FID) and gas chromatography with electron capture detector (GC‑µECD) using two columns: DB-35ms (intermediate polarity) and DB-XLB (low polarity). The water content was determined by Karl Fischer coulometric titration, and the inorganics were analyzed by inductively coupled plasma mass spectrometry (ICP-MS). The aldrin contents determined by mass balance and quantitative nuclear magnetic resonance (qNMR) were compared. The obtained results were validated through the participation of the National Institute of Metrology, Quality and Technology (Inmetro) in the key-comparison CCQM-K55.b organized by the Organic Analysis Working Group/International Bureau of Weights and Measures (OAWG/BIPM).

https://doi.org/10.5935/0103-5053.20150047 2663 downloads

Posição prona e diminuição da assincronia toracoabdominal em recém-nascidos prematuros
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Oliveira, Trícia G.

; Rego, Maria A. S.

; Pereira, Nadja C.

; Vaz, Lorena O.

; França, Danielle C.

; Vieira, Danielle S. R.

; Parreira, Verônica F.

Jornal de Pediatria

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oct 2009, Volume 85 N. 5 Pages 443 - 448

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: Avaliar a influência das posições prona e supina em recém-nascidos prematuros pós-síndrome do desconforto respiratório, respirando espontaneamente e em estado de sono ativo, sobre variáveis de padrão respiratório, movimento toracoabdominal e saturação periférica da hemoglobina pelo oxigênio. MÉTODOS: Estudo quase experimental. Doze prematuros com peso > 1.000 g no momento do estudo foram estudados nas duas posições, em ordem randomizada. A pletismografia respiratória por indutância foi utilizada para avaliação do padrão respiratório (volume corrente, frequência respiratória, ventilação minuto, fluxo inspiratório médio) e do movimento toracoabdominal (índice de trabalho respiratório, relação de fase inspiratória, relação de fase expiratória, relação de fase respiratória total e ângulo de fase). A oximetria de pulso registrou a saturação periférica de oxigênio. Para a análise estatística foram realizados os testes t de Student para amostras pareadas ou Wilcoxon. Foi considerado significativo p < 0,05. RESULTADOS: Foram analisados 9.167 ciclos respiratórios. Na posição prona, houve redução significativa do índice de trabalho respiratório (-0,84±0,69; p = 0,001; IC95% -1,29 a -0,40), das relações de fase inspiratória (-27,36±17,55; p = 0,000; IC95% -38,51 a -16,20), expiratória (-32,36±16,20; p = 0,000; IC95% -42,65 a -22,06) e total (-30,20±14,76; p = 0,000; IC95% -39,59 a -20,82). Não houve diferença significativa entre as posições nas demais variáveis analisadas. CONCLUSÃO: A posição prona promoveu diminuição significativa da assincronia toracoabdominal, sem influenciar o padrão respiratório e a saturação periférica de oxigênio.

OBJECTIVE: To assess the effect of prone and supine positions on breathing pattern variables, thoracoabdominal motion and peripheral oxygen saturation of hemoglobin of premature newborn infants recovering from respiratory distress syndrome, while breathing spontaneously and in rapid eye movement sleep. METHODS: This was a quasi-experimental study. Twelve preterms weighing > 1,000 g at enrollment were studied in both positions, in random order. Respiratory inductive plethysmography was used to analyze breathing pattern (tidal volume, respiratory rate, minute ventilation, mean inspiratory flow) and thoracoabdominal motion (labored breathing index, phase relation in inspiration, phase relation in expiration, phase relation in total breath and phase angle). Pulse oximetry was used to evaluate peripheral oxygen saturation. Student's t test for paired samples or the Wilcoxon test were used for statistical analysis. Significance was set at p < 0.05. RESULTS: A total of 9,167 respiratory cycles were analyzed. The prone position was associated with significant reductions in labored breathing index (-0.84±0.69; p = 0.001; 95%CI -1.29 to -0.40), phase relation in inspiration (-27.36±17.55; p = 0.000; 95%CI -38.51 to -16.20), phase relation in expiration (-32.36±16.20; p = 0.000; 95%CI -42.65 to -22.06) and phase relation in total breath (-30.20±14.76; p = 0.000; 95%CI -39.59 to -20.82). There were no significant differences between the two positions in any of the other variables analyzed. CONCLUSION: The prone position resulted in a significant reduction in thoracoabdominal asynchrony, without affecting breathing pattern or peripheral oxygen saturation.

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Análise descritiva dos perfis social, clínico, laboratorial e antropométrico de pacientes com doenças inflamatórias intestinais, internados no Hospital Universitário Clementino Fraga Filho, Rio de Janeiro
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Elia, Paula Peruzzi

; Fogaça, Homero Soares

; Barros, Rodrigo G. G. Rego

; Zaltman, Cyrla

; Elia, Celeste Siqueira C.

Arquivos de Gastroenterologia

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dec 2007, Volume 44 N. 4 Pages 332 - 339

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RACIONAL: Estudos epidemiológicos sobre doenças inflamatórias intestinais no Brasil são limitados devido a dificuldades diagnósticas e reduzidas amostras populacionais estudadas. A maioria dos estudos de sua prevalência disponível é composta por amostras de pacientes sob acompanhamento em ambulatório, entretanto a análise do perfil de pacientes com doenças inflamatórias intestinais hospitalizados pode auxiliar na detecção de marcadores preditivos de sua gravidade, o que permitirá intervenções médicas precoces visando a redução da taxa de hospitalização e os gastos do sistema de saúde. OBJETIVOS: Descrever o perfil social, clínico, laboratorial e antropométrico dos pacientes adultos com doenças inflamatórias intestinais internados em hospital universitário terciário. MÉTODOS: Estudo prospectivo com 43 pacientes com doenças inflamatórias intestinais internados nas enfermarias clínicas e cirúrgicas e no setor de emergência do Hospital Universitário Clementino Fraga Filho da Universidade Federal do Rio de Janeiro, RJ. Foram caracterizados dados demográficos, presença de co-morbidades, localização e comportamento clínico, história cirúrgica, manifestações extra-intestinais utilizando-se definições padronizadas. Os resultados laboratoriais foram verificados nos prontuários e as medidas antropométricas foram realizadas durante a entrevista. RESULTADOS: A maioria dos pacientes apresentou doença de Crohn (72,1%), com localização íleo-colônica (60%) e com comportamento penetrante (77,4%), enquanto no grupo retocolite ulcerativa idiopática predominou a pancolite (50%). No grupo total de retocolite ulcerativa idiopática, a artralgia foi a manifestação extra-intestinal mais freqüente (44,2%) e 97,7% já havia apresentado algum tipo de complicação relacionada à doença de base. Apesar do uso de terapêutica específica para doenças inflamatórias intestinais prévio à hospitalização em 79,1% dos enfermos, as causas mais freqüentes de internação estavam relacionadas à atividade de doença. A presença de co-morbidades só ocorreu em 30,2%. CONCLUSÃO: Os pacientes com doenças inflamatórias intestinais internados nas enfermarias do Hospital apresentam doença grave, em atividade, com complicações e manifestações extra-intestinais freqüentes, apesar do uso prolongado de corticóide. A doença de Crohn, por apresentar evolução mais agressiva, representou a maior parcela dos pacientes internados. A hipoalbuminemia, a anemia e as alterações antropométricas são comuns nos pacientes hospitalizados, podendo estar relacionadas a sua maior gravidade evolutiva.

BACKGROUND: The epidemiologic survey in Brazil is limited probably due to a diagnosis deficiency and a small number of population-based studies performed. The majority of the prevalence studies available have evaluated inflammatory bowel diseases outpatients, but the knowledge of the profile of inflammatory bowel diseases inpatients is important in order to detect predictive markers of disease severity that will allow earlier medical intervention decreasing the rate of hospitalization and reducing the Health System costs. AIM: To determine social, clinical, laboratorial and anthropometric profiles of hospitalized adults inflammatory bowel diseases patients of a tertiary university hospital. METHODS: Prospective study was performed with 43 inflammatory bowel diseases inpatients from clinical and surgical wards and emergency section of university hospital. We characterized demographic data, presence of comorbidities, disease location and behavior, surgical past-history, extra intestinal manifestations using standardized definitions. Laboratory results were abstracted from medical records and anthropometric measures were performed during our visit. RESULTS: The vast majority of the inflammatory bowel diseases patients had Crohn's disease (72.1%), with ileocolic involvement (60%), with a penetrating disease behavior (77.4%) while ulcerative colitis group presented mostly pancolitis (50%). Articular pain was the most common (44.2%) extra intestinal manifestation of inflammatory bowel diseases patients and 97.7% of them had at least one type of complication related to disease. Although, the previous use of specific medical therapies to inflammatory bowel diseases before the hospitalization (more frequently corticosteroids) was done (79%), the majority of the patients were hospitalized because of inflammatory bowel diseases activity. Disease activity was present in 80.7% of Crohn's disease and 50% ulcerative colitis patients. Inflammatory bowel diseases mortality rate was 5.5% (2/36). Comorbidities presence occurred only in 30.2% of inflammatory bowel diseases patients. The predominant surgery performed was intestinal resection. The interval between the symptoms appearance and the definitive diagnosis was less than 1 year in more than 70% of inflammatory bowel diseases patients. Laboratory findings detected were a decreased serum albumin (85.7%) and anemia (69.8%). The majority of the patients had at least one anthropometric alteration. The social stratification of the inflammatory bowel diseases group was similar to the Brazilian population. CONCLUSION: The inflammatory bowel diseases inpatients from the university hospital wards had more severe evolution of these illnesses with an active and extensive disease with complications and frequent extra intestinal manifestations, despite the prolonged use of corticosteroids. The higher prevalence of Crohn's disease inpatients than ulcerative colitis could reflect a higher aggressive behavior of this disease. The reduced serum albumin, anemia and anthropometric alterations are common inflammatory bowel diseases inpatients and could be related to a major severity of inflammatory bowel diseases evolution.

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10.

Asma em escolares do Recife - comparação de prevalências: 1994-95 e 2002
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Britto, Murilo C. A.

; Bezerra, Patrícia G. M.

; Brito, Rita C. C. M.

; Rego, Joakim C.

; Burity, Edjane F.

; Alves, João G. B.

Jornal de Pediatria

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2004, Volume 80 N. 5 Pages 391 - 400

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVOS: Descrever a prevalência atual (2002) de asma e suas variantes em escolares da cidade do Recife, comparando os dados com o período de 1994-95; analisar a relação entre instrução materna e o surgimento ou o agravamento da asma; e avaliar a acurácia diagnóstica da prevalência anual de sibilância como indicador de asma. MÉTODO: Em um corte transversal, estudou-se, por questionário escrito, uma amostra probabilística de escolares de 13 e 14 anos em Recife, em 1994-95 (n = 3.086) e 2002 (n = 2.774), como parte do projeto ISAAC (International Study of Asthma and Allergies in Childhood). RESULTADOS: Em 1994-95 e 2002, as prevalências foram, respectivamente: cumulativa de asma referida, 21 e 18,2%; cumulativa de sibilância, 39 e 38%; anual de sibilância, 19,7 e 19,4%; anual de tosse equivalente de asma, 31 e 38%; anual de sibilância desencadeada por exercício, 20,6 e 23,8%. A prevalência anual de crises, estratificada em 1 a 3, 4 a 12 e mais de 12 foi: 16,3, 2,7 e 1% em 1994-95 e 15,2, 1,2 e 0,4% em 2002. A prevalência anual de crises que comprometeram o sono foi, respectivamente, de 13 e 10,3%; a prevalência de crises com prejuízo da fala foi de 4,8 e 4,1%. Nível mais elevado de instrução materna associou-se a maior prevalência cumulativa de asma referida, prevalência cumulativa e anual de sibilância. CONCLUSÕES: A prevalência de asma e suas formas graves é elevada em escolares adolescentes do Recife e está associada a maior instrução materna.

OBJECTIVES: To describe the prevalence of asthma and asthma variants in schoolchildren from Recife in 2002, and to compare these data with data from 1994-95; to analyze the relationship between maternal schooling and the presence of asthma or worsening asthma; and to evaluate the diagnostic accuracy of the yearly prevalence of wheezing as an asthma indicator. METHODS: Cross-sectional study. A probabilistic sample of 3,086 and 2,774 13- and 14-year-old students answered a written questionnaire in 1994-95 and 2002, as part of the International Study of Asthma and Allergies in Childhood. RESULTS: The following prevalence rates were observed in 1994-95 and 2002, respectively: cumulative prevalence of referred asthma: 21 vs. 18.2%; cumulative prevalence of wheezing: 39 vs. 38%; yearly prevalence of wheezing: 19.7 vs. 19.4%; yearly prevalence of night cough: 31 vs. 38%; yearly prevalence of exercise-induced wheezing: 20.6 vs. 23.8%. The yearly prevalence of asthma attacks was 16.3% vs. 15.2% for 1 to 3 attacks; 2.7% vs. 1.2% for 4 to 12 attacks; and 1% vs. 0.4% for more than 12 attacks. The yearly prevalence of attacks that disturbed sleep was 13 and 10.3%. The yearly prevalence of attacks with compromised speech was 4.8 and 4.1%. Higher levels of maternal schooling were related to higher cumulative prevalence of referred asthma and to cumulative and yearly prevalence of wheezing. CONCLUSIONS: The prevalence of asthma and its severe forms is high in teenager students in Recife. It is also related to higher levels of maternal schooling.

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11.

I Consenso Nacional para Padronização dos Laudos de FAN HEp-2
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Dellavance, Alessandra

; G. Júnior, Alexandre

; Cintra, Alice F.U.

; Ximenes, Antônio C.

; Nuccitelli, Barbara

; Mühlen, Carlos A. von

; Bichara, Carlos D.

; Yano, Cristiane

; Carvalho, Darlene G.

; Bonfá, Eloísa S.D.O.

; Guimarães, Fabiana N.C.

; Mundim, Hugo M.

; Pfrimer, Irmtraut A.H.

; Rego, Jozelia

; Andrade, Luiz E.C.

; Mesquita, Mauro M.

; Santiago, Mittermayer B.

; Silva, Nilzio A.

; Miranda, Paulo J.

; Leser, Paulo

; Francescantonio, Paulo Luiz C.

; Jarach, Renata

; Levy, Roger A.

; Neves, Suzane P.F.

; Cruvinel, Wilson M.

; Santos, Wilton S.

Jornal Brasileiro de Patologia e Medicina Laboratorial

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jul 2002, Volume 38 N. 3 Pages 207 - 216

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A análise da presença de auto-anticorpos feita por imunofluorescência indireta em células HEp-2 constitui-se em um método de triagem escolhido na maioria dos laboratórios clínicos. A ausência de uma nomenclatura definida para a descrição dos laudos tem trazido problemas na utilização clínica do teste, pelas dificuldades no controle de qualidade e na padronização dos resultados, que, por sua vez, embora similares, recebiam denominações diferentes. O I Consenso Brasileiro para Padronização dos Laudos de FAN HEp-2 reuniu em agosto de 2000, em Goiânia, diversos especialistas de todo o Brasil. Esses emitiram pareceres em consenso para os distintos padrões: nucleares, nucleolares, citoplasmáticos e aparelho mitótico. Foram feitas recomendações sobre os critérios para a leitura de uma lâmina, bem como para relação entre a diluição de triagem e o sistema óptico utilizado.

The technique of immunofluorescence using HEp-2 cells as substrate is the screening method of choice for the presence of autoantibodies in many clinical laboratories. The lack of a specific terminology for reporting results brings problems in quality control, clinical utility of the test, and standardization attempts. The first Brazilian Consensus for Standardization of ANA in HEp-2 Cells took place in Goiânia in August 2000. Several laboratory specialists with experience in the methodology showed up. They established guidelines for the description of ANA patterns in the Portuguese language, encompassing distinct descriptions for nuclear, nucleolar, cytoplasmic and mitotic apparatus patterns of fluorescence. Recommendations were also established regarding screening titers, final dilution titer, and on morphological criteria for reading the slides.

11489 downloads Cited 5 times in SciELO

12.

I Diretrizes do Grupo de Estudos em Cardiogeriatria da Sociedade Brasileira de Cardiologia
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Franken, Roberto Alexandre

; Taddei, Cláudia F. Gravina

; Maia, Ivan Gonçalves

; Batlouni, Michel

; Sousa, J.Eduardo Moraes Rego

; Wajngarten, Maurício

; Feitosa, Gilson Soares

; Lorga, Adalberto

; Paola, Angelo de

; Scatolini Neto, Argemiro

; Halperin, Cidio

; Moreira, Dalmo

; Hachul, Denise

; Savioli, Felicio

; Atiê, Jacob

; Gagliardi, Rubens

; Avezum, Alvaro

; Bocchi, Edimar A.

; Dohmann, Hans J. F.

; Pereira Filho, Ilnei

; Saraiva, J. Francisco Kerr

; Bodanese, Luis C.

; Leal, Marcelo Garcia

; Afiune Neto, Abrahão

; Libberman, Alberto

; Sousa, Amanda G. M. R.

; Sousa, Antonio Carlos S.

; Caramelli, Bruno

; Geraldez, Roberto R.C.

; Brandão, Airton P.

; Markman Filho, Brivaldo

; Amodeo, Celso

; Ferreira, Celso

; Souza Filho, João

; Siqueira, J Eduardo

; Gonçalves Júnior, Iran

; Makdisse, Marcia P.

; Luna, Rafael L

; Rosa, Ronaldo F.

; Luis, Carlos de Camargo

; Freitas, Elizabete Viana

; Tarasoutchi, Flávio

; Pierri, Humberto

; Santos, Silvio Carlos de M.

; Meneghello, Zilda M.

; Magalhães, Carlos C.

; Nasri, Fabio

; Gus, Iseu

; Borges, Jairo

; Serro Azul, João Batista

; Aldrighi, José M.

; Ghorayeb, Nabil

; Grespan, Stela Maris

Arquivos Brasileiros de Cardiologia

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2002, Volume 79 Suppl. 1 Pages 1 - 46

Abstract: Pt | Text: Pt | PDF: Pt

50012 downloads Cited 1 time in SciELO

13.

Trypanosoma nupelianus sp. n. (Protozoa, Kinetoplastida) parasitizing rhinelepis aspera (Osteichthyes, Loricariidae) from Paraná river, Brazil
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Eiras, J. C.

; Rego, A. A.

; Pavanelli, G. C.

Memórias do Instituto Oswaldo Cruz

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jun 1990, Volume 85 N. 2 Pages 183 - 184

Abstract: En | Text: En | PDF: En

It is described Trypanosoma nupelianus sp. n. parasitizing Rhinelepis aspera taken from Paraná river (Itaipu reservoir, Brazil). Morphometric characters such as body length, width of the body and nucleus dimensions show that T. nupelianus sp. n. is different from other trypanosomes described for fishes from tropical regions.

1178 downloads Cited 1 time in SciELO

14.

Trypanosoma guairaensis sp. n. (Protozoa, Kinetoplastida) parasita de megaloancistrus aculeatus (Perugia, 1891) (Pisces, Loricariidae)
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Eiras, J. C.

; Rego, A. A.

; Pavanelli, G. C.

Memórias do Instituto Oswaldo Cruz

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sep 1989, Volume 84 N. 3 Pages 389 - 392

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Descreve-se a espécie Trypanosoma guairaensis sp. n. parasita de Megaloancistrus aculeatus do rio Paraná (reservatório de Itaipu). Características morfométricas como comprimento e largura do núcleo e comprimento da parte livre do flagelo, bem como os valores do índice nuclear, diferenciam T. guairaensis de todas as espécies de tripanosomas descritas para peixes de água doce do Brasil.

It is described Trypanosoma guairaensis sp. n. parasitizing Megaloancistrus aculeatus taken from Paraná river (Itaipu reservoir). Morphometric characters such as length and width of the nucleus, length of the free flagellum and nuclear index values show that T. guairaensis is different from all the trypanosome species so far described for fresh water fishes from Brazil.

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