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ABSTRACT Introduction: Although competitiveness rises progressively increases according to age groups, players must stand out in their playing position at all ages to win a spot on their National Teams. The differences among match physical and technical demands could also influence which anthropometrical aspects would be most importantly considered for National Team selection. Objectives: This study aimed describe and compare the anthropometric profile of soccer players from U15 to professional categories of the Brazilian National Soccer Team. Methods: The sample consisted of 673 players from the categories U15, U17, U20, U23 and PRO. Measurements of height, body mass, and sum of seven skinfolds from the Brazilian Football Confederation database between 2013 and 2021 were used to describe the players’ anthropometric profile. Players were grouped according to categories, playing position, and those who were selected or not selected. Results: As expected, the results indicate that body mass increases with age and stabilizes from category U23 onwards. Body mass and the sum of seven skinfolds increase within the U15 category (U15.1 vs. U15.2), while height and body mass increase within the U17 category (U17.1 vs. U17.2). Defenders and fullbacks stabilize body mass and stature prior to U17, while midfielders, strikers, and goalkeepers stabilize body mass later, with midfielders and strikers at U20, and goalkeepers at U23. Goalkeepers and defenders were the players with the greatest height and body mass compared to the other positions in all categories. The selected and non-selected players in the different categories had similar anthropometric profiles. Conclusion: From the results, there is a diversity in anthropometric profile within the positions and a difference in maturation according to the players’ positions. This study can be used by coaches, physical trainers and sport scientists as normative data about the anthropometric profile of Brazilian men's soccer teams, establishing a benchmark. Level of Evidence III; Retrospective and Comparative Study.

RESUMEN Introducción: Aunque la competitividad aumenta progresivamente según los grupos de edad, los jugadores deben destacar en su posición de juego a todas las edades para ganarse un puesto en sus selecciones nacionales. Las diferencias entre las exigencias físicas y técnicas de los partidos también pueden influir en qué aspectos antropométricos serían más importantes para la selección nacional. Objetivos: Este estudio tuvo como objetivo describir y comparar el perfil antropométrico de futbolistas masculinos de menores de 15 años a categorías mayores de las selecciones brasileñas de fútbol. Métodos: La muestra estuvo compuesta por 673 jugadores de las siguientes categorías: Sub 15 (U15), Sub 17 (U17), Sub 20 (U20), Sub 23 (U23) y Profesional (PRO). Se utilizaron medidas de estatura, masa corporal y la suma de 7 pliegues cutáneos de la base de datos de la Confederación Nacional de Fútbol de Brasil entre 2013 y 2021 para describir el perfil antropométrico de los jugadores. Los jugadores se agruparon según los tramos de edad oficiales, la posición de juego y los seleccionados y no seleccionados. Resultados: Como era de esperar, los resultados indican que la masa corporal aumenta con la edad y se estanca a partir de la categoría U23. La masa corporal y la suma de 7 pliegues cutáneos aumentan dentro de la categoría U15 (U15.1 vs. U15.2), mientras que la estatura y la masa corporal aumentan dentro de la U17 (U17.1 vs. U17.2). Los defensas centrales y los laterales estabilizan antes la masa corporal y la estatura a partir de la U17, mientras que los mediocampistas, delanteros y porteros estabilizan la masa corporal más tarde, con los mediocampistas y delanteros en la U20 y los porteros en la U23. Los porteros y defensas centrales fueron los grupos que mostraron mayor estatura y masa corporal respecto a otras posiciones en todos los tramos de edad. Los jugadores seleccionados y no seleccionados en diferentes tramos de edad tienen un perfil antropométrico similar. Conclusión: Con base en los resultados, existe diversidad en el perfil antropométrico dentro de las posiciones de juego y diferencia en la maduración según la posición de los jugadores. Este estudio puede ser utilizado por entrenadores, preparadores físicos y científicos del deporte como dato normativo sobre el perfil antropométrico de las selecciones masculinas de fútbol de Brasil, estableciendo un punto de referencia. Nivel de Evidencia III; Estudio Retrospectivo Comparativo.

RESUMO Introdução: Embora a competitividade aumente progressivamente de acordo com as faixas etárias os jogadores devem se destacar em sua posição de jogo em todas as idades para conquistar uma vaga em suas equipes nacionais. As diferenças entre as exigências físicas e técnicas dos jogos também podem influenciar quais aspectos antropométricos seriam mais importantes para a seleção da equipe nacional. Objetivo: Este estudo teve por objetivo descrever e comparar o perfil antropométrico de jogadores de futebol da categoria sub 15 ao profissional da Seleção Brasileira de Futebol. Métodos: A amostra consistiu de 673 jogadores das seguintes categorias: sub 15 (U15) sub 17 (U17) sub 20 (U20) sub 23 (U23) e profissional (PRO). Medidas da estatura massa corporal e soma das sete dobras cutâneas do banco de dados da Confederação Brasileira de Futebol entre 2013 e 2021 foram utilizadas para descrever o perfil antropométrico dos jogadores. Os jogadores foram agrupados de acordo com as categorias posição de jogo e aqueles que foram selecionados ou não selecionados. Resultados: Como esperado os resultados indicam que a massa corporal aumenta com a idade e estabiliza a partir da categoria U23. A massa corporal e a soma das sete dobras cutâneas aumentam dentro da categoria U15 (U15.1 vs. U15.2) enquanto a estatura e a massa corporal aumentam dentro da categoria U17 (U17.1 vs. U17.2). Os zagueiros e laterais estabilizam a massa corporal e a estatura antes do U17 enquanto os meio campistas atacantes e goleiros estabilizam a massa corporal posteriormente com os meio campistas e atacantes no U20 e goleiros no U23. Os goleiros e os zagueiros foram os jogadores que apresentaram maior estatura e massa corporal comparados às outras posições em todas as categorias. Os jogadores selecionados e não-selecionados nas diferentes categorias apresentam perfil antropométrico semelhante. Conclusão: Baseando-se nos resultados há uma diversidade no perfil antropométrico dentro das posições e uma diferença na maturação de acordo com as posições dos jogadores. Este estudo pode ser utilizado por treinadores preparadores físicos e cientistas do esporte como dados normativos sobre o perfil antropométrico das seleções masculinas do futebol brasileiro estabelecendo um benchmark. Nível de Evidência III; Estudo Retrospectivo Comparativo.

https://doi.org/10.1590/1517-8692202430012022_0425i

Vaccination strategies for people living with inborn errors of metabolism in Brazil
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Ramos, Barbara CF

; Aranda, Carolina S

; Cardona, Rita S.B

; Martins, Ana Maria

; Solé, Dirceu

; Clemens, Sue Ann C

; Clemens, Ralf

Jornal de Pediatria

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apr 2023, Volume 99 Suppl. 1 Pages S70 - S80

Abstract: En | Text: En | PDF: En

Abstract Objective: Through a literature review, make recommendations regarding immunizations in people living with Inborn Error of Metabolism (IEM) in Brazil, assess the possible impact on metabolic decompensations after immunization, and if this specific population may have an impaired immune response to vaccines. Source of data: The MeSH Terms vaccination OR vaccine OR immunization associated with the term inborn error of metabolism AND recommendation were used in combination with search databases. Only articles published after 1990, in the languages English, Spanish, French or Portuguese, human-related were included. Synthesis of data: A total of 44 articles were included to make the following recommendations. Individuals with IEMs need to be up to date with their immunizations. Regarding which vaccines should be offered, children and adults should follow the routine immunization schedules locally available, including the COVID-19 vaccines. The only exception is the rotavirus vaccine for hereditary fructose intolerance. The benefit of immunization outweighs the very low risk of metabolic decompensation. Since not all patients will have an adequate immune response, measuring antibody conversion and titers is recommended Conclusions: All patients should receive age-appropriate immunizations in their respective schedules without delays. The only situation when vaccination may be contraindicated is with oral rotavirus vaccine in hereditary fructose intolerance. Monitoring the levels of antibodies should be done to detect any immune dysfunction or the necessity for boosters. A personalized immunization schedule is ideal for patients with IEMs. The reference organizations could improve their recommendations to address all IEMs, not only some of them.

https://doi.org/10.1016/j.jped.2022.12.001

Knowledge regarding extracorporeal membrane oxygenation management among Brazilian pediatric intensivists: a cross-sectional survey
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Colleti Júnior, José

; Prata-Barbosa, Arnaldo

; Araujo, Orlei Ribeiro

; Tonial, Cristian Tedesco

; Oliveira, Felipe Rezende Caino de

; Souza, Daniela Carla de

; Lima-Setta, Fernanda

; Oliveira, Thiago Silveira Jannuzzi de

; Mello, Mary Lucy Ferraz Maia Fiuza de

; Amoretti, Carolina

; João, Paulo Ramos David

; Neves, Cinara Carneiro

; Oliveira, Norma Suely

; Costa, Cira Ferreira Antunes

; Garros, Daniel

Critical Care Science

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jan 2023, Volume 35 N. 1 Pages 57 - 65

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar os conhecimentos gerais dos intensivistas pediátricos brasileiros sobre oxigenação por membrana extracorpórea, incluindo evidências de uso, modelo de custeio nacional, indicações e complicações. Métodos: Este estudo foi um inquérito transversal multicêntrico que incluiu 45 unidades de terapia intensiva pediátrica brasileiras. Realizou-se inquérito de conveniência com 654 intensivistas quanto aos seus conhecimentos sobre manejo de pacientes em oxigenação por membrana extracorpórea, suas indicações, complicações, custeio e evidências bibliográficas. Resultados: O inquérito abordou questões relativas aos conhecimentos e à experiência dos intensivistas pediátricos sobre oxigenação por membrana extracorpórea, incluindo dois casos clínicos e seis questões facultativas sobre o manejo de pacientes em oxigenação por membrana extracorpórea. Dos 45 centros convidados, 42 (91%) participaram do estudo, e 412 (63%) dos 654 intensivistas pediátricos responderam ao inquérito. A maioria das unidades de terapia intensiva pediátrica eram da Região Sudeste do Brasil (59,5%), e os hospitais privados com fins lucrativos representavam 28,6% dos centros participantes. A média de idade dos respondentes era de 41,4 (desvio-padrão de 9,1) anos, e a maioria (77%) era mulher. Apenas 12,4% dos respondentes tinham formação em oxigenação por membrana extracorpórea. Dos hospitais pesquisados, apenas 19% tinham um programa de oxigenação por membrana extracorpórea, e apenas 27% dos intensivistas declararam já ter manejado pacientes em oxigenação por membrana extracorpórea. Apenas 64 médicos (15,5%) responderam a questões específicas sobre o manejo de oxigenação por membrana extracorpórea (mediana 63,4%; oscilando entre 32,8% e 91,9%). Conclusão: A maioria dos intensivistas pediátricos brasileiros demonstrou conhecimentos limitados de oxigenação por membrana extracorpórea, incluindo suas indicações e complicações. A oxigenação por membrana extracorpórea ainda não está amplamente disponível no Brasil, com poucos intensivistas preparados para o manejo de pacientes em oxigenação por membrana extracorpórea e ainda menos intensivistas capazes de reconhecer quando devem encaminhar pacientes para centros de oxigenação por membrana extracorpórea.

ABSTRACT Objective: To assess Brazilian pediatric intensivists’ general knowledge of extracorporeal membrane oxygenation, including evidence for its use, the national funding model, indications, and complications. Methods: This was a multicenter cross-sectional survey including 45 Brazilian pediatric intensive care units. A convenience sample of 654 intensivists was surveyed regarding their knowledge on managing patients on extracorporeal membrane oxygenation, its indications, complications, funding, and literature evidence. Results: The survey addressed questions regarding the knowledge and experience of pediatric intensivists with extracorporeal membrane oxygenation, including two clinical cases and 6 optional questions about the management of patients on extracorporeal membrane oxygenation. Of the 45 invited centers, 42 (91%) participated in the study, and 412 of 654 (63%) pediatric intensivists responded to the survey. Most pediatric intensive care units were from the Southeast region of Brazil (59.5%), and private/for-profit hospitals represented 28.6% of the participating centers. The average age of respondents was 41.4 (standard deviation 9.1) years, and the majority (77%) were women. Only 12.4% of respondents had taken an extracorporeal membrane oxygenation course. Only 19% of surveyed hospitals have an extracorporeal membrane oxygenation program, and only 27% of intensivists reported having already managed patients on extracorporeal membrane oxygenation. Specific extracorporeal membrane oxygenation management questions were responded to by only 64 physicians (15.5%), who had a fair/good correct response rate (median 63.4%; range 32.8% to 91.9%). Conclusion: Most Brazilian pediatric intensivists demonstrated limited knowledge regarding extracorporeal membrane oxygenation, including its indications and complications. Extracorporeal membrane oxygenation is not yet widely available in Brazil, with few intensivists prepared to manage patients on extracorporeal membrane oxygenation and even fewer intensivists recognizing when to refer patients to extracorporeal membrane oxygenation centers.

https://doi.org/10.5935/2965-2774.20230350-en

The Contribution of Meteorological Parameters and the COVID-19 Partial Lockdown on Air Quality in Rio de Janeiro, Brazil
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Beringui, Karmel

; Justo, Elizanne P. S.

; Ventura, Luciana M. B.

; Gomes, Ruan G. S.

; Lionel-Mateus, Vinícius

; Cruz, Alex H. De La

; Almeida, Ana Carolina L. B. de

; Ramos, Michelle B.

; Suazo, Julio Angeles

; Valle, Pedro H. R.

; Gioda, Adriana

Journal of the Brazilian Chemical Society

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jan 2023, Volume 34 N. 1 Pages 69 - 82

Abstract: En | Text: En | PDF: En

This study evaluated the pollutant levels (NO2, SO2, CO, and O3), air quality index (AQI) and the influence of meteorological variables and coronavirus disease (COVID-19) pandemic on the air quality in Rio de Janeiro. The data set used comprises periods before (March-April, 2019) and during pandemic (March-April, 2020). According to the AQI results, on most days, the air quality was ranked as “good”. Brazilian air quality standards for SO2, O3, and NO2 were not exceeded in any of the monitoring stations during partial lockdown, while CO exceeded in all periods in one site due to industrial emission. Comparing both periods, descriptive statistics for the meteorological parameters presented no differences, which suggests similar conditions. However, when evaluated week by week in 2020, weather conditions presented some differences that probably affected pollutant concentrations. The correlations between O3 and NO2 and some meteorological parameters indicate that variations in both favored ozone formation, since it is a photochemical process favored by temperature and solar radiation and that, in Rio de Janeiro, low NO2 concentrations lead to increased O3. The improvements on air quality during the partial lockdown may be attributed mainly to a reduction on emission sources rather than weather conditions.

https://doi.org/10.21577/0103-5053.20220089

Gingivitis in calves: longitudinal hematological and metabolic profiles- and salivary buffering capacity in animals treated with virginiamycin
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Vaccari, Juliana

; Ramos, Thamiris Naiasha Minari

; Gaetti-Jardim Júnior, Elerson

; Chaves-Neto, Antonio Hernandes

; Borsanelli, Ana Carolina

; Saraiva, Júlia Rebecca

; Souza, Natália Cristina de

; Bomfim, Suely Regina Mogami

; Schweitzer, Christiane Marie

; Dutra, Iveraldo dos Santos

Ciência Rural

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2023, Volume 53 N. 12 elocation e20240475

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT: Gingivitis is an infectious inflammatory process that generates local and systemic conditions, compromising the masticatory capacity of animals. Virginiamycin controls and prevents gingivitis and necrotizing gingivitis in cattle. However, the interaction and effect with different sera and salivary elements remain unknown. The present 6-month longitudinal study evaluated the hematological, metabolic, and salivary buffering capacity profiles of calves with gingivitis treated with virginiamycin. Ten calves were divided into two groups: control and virginiamycin (n = 5 each). Calves in the virginiamycin group had a lower occurrence of gingivitis (P < 0.01, Student’s t-test). The animals that developed gingivitis in both experimental groups had higher salivary levels of alkaline phosphatase (P = 0.01915) and lower serum levels of albumin (P = 0.0028). Additionally, animals receiving virginiamycin had higher serum levels of magnesium (P = 0.008), albumin (P = 0.0008), urea (P = 0.008), alkaline phosphatase (P = 0.008), total proteins (P = 0.008), and plasma protein (P = 0.018). Salivary buffering capacity was negatively correlated with salivary variables such as calcium, magnesium, albumin, total protein, and aspartate aminotransferase and serum variables such as albumin and aspartate aminotransferase. Results of the present study suggested that the occurrence of periodontopathies in episodes is reflected in the local and systemic alterations in animals. In this context, clinical periodontal monitoring also showed the benefits of virginiamycin supplementation on gingival conditions and systemic health markers, in addition to controlling the two precursor forms of periodontitis.

RESUMO: Gengivites são processos infecto-inflamatórios que geram quadros locais e sistêmicos, com comprometimento da capacidade mastigatória dos animais. A virginiamicina controla e previne a gengivite e a gengivite necrosante em bovinos; no entanto, a interação e efeito com diferentes elementos séricos e salivares permanecem desconhecidos. O presente estudo teve como objetivo avaliar, em um estudo longitudinal com duração de seis meses, os perfis hematológicos, metabólicos e de capacidade tamponante salivar de bezerros com gengivite e tratados com virginiamicina. Foram utilizados 10 bezerros divididos em dois grupos: grupo controle (n = 5) e grupo virginiamicina (n = 5). Os bezerros do grupo virginiamicina apresentaram menor ocorrência de gengivite (P < 0,01, teste T - Student). Os animais que desenvolveram gengivite, de ambos os grupos experimentais, apresentaram níveis salivares mais elevados de fosfatase alcalina (P = 0,01915) e níveis séricos menores de albumina (P = 0,0028). Observou-se também que os animais que receberam virginiamicina apresentaram níveis séricos mais elevados de magnésio (P = 0,008), albumina (P = 0,0008), ureia (P = 0,008), fosfatase alcalina (P = 0,008), proteínas totais (P = 0,008) e proteína plasmática (P = 0,018). As análises de capacidade tamponante salivar foram correlacionadas negativamente às variáveis salivares como cálcio, magnésio, albumina, proteína total e aspartato aminotransferase e às variáveis séricas como a albumina e aspartato aminotransferase. Os resultados do presente estudo sugerem que a ocorrência em episódios das periodontopatias refletem-se em alterações locais e sistêmicas nos animais. Neste contexto, o monitoramento clínico periodontal também evidenciou os benefícios do emprego de suplementação pela virginiamicina sobre as condições gengivais e marcadores sistêmicos de saúde, além do controle das duas formas precursoras de periodontites.

https://doi.org/10.1590/0103-8478cr20240475

Numerical Prediction for the Effects of Welding Interpass Temperature on the Thermal History and Microstructure of Duplex Stainless Steels
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Xavier, Carlos Roberto

; Delgado Junior, Horácio Guimarães

; Rebello, Matheus Gomes

; Lisbôa, Raí Ramos

; Silva, Ana Carolina Martins

; Castro, José Adilson de

Materials Research

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2023, Volume 26 elocation e20220529

Abstract: En | Text: En | PDF: En

Numerical simulation was used to predict the thermal behavior and the resulting microstructure at the heat-affected zone (HAZ) of a 170 mm diameter and 3.5 mm thickness super duplex stainless steel (SDSS) UNS S32750 tube. In order to evaluate the thermal response from the model, a usual welding situation involving interpass temperature (IT) and its influence on the HAZ microstructure was exploited. Thus, two superimposed autogenous welding passes were simulated, the first clockwise with the tube in the room temperature and the second, counterclockwise, with the tube at the temperature of 250oC. Even subjected to successive thermal cycles and high interpass temperature, the proportion and morphology of the phases at the HAZ and Fusion Zone (FZ) did not present significant differences when comparing the two welding passes. Meanwhile, nitrogen losses should be avoided during welding in order to obtain a balanced microstructure in DSS welds, contributing to guarantee satisfactory toughness in addition to resistance to pitting corrosion. The predictions from the simulation were validated by using experimental results obtained from the autogenous TIG (Tungsten Inert Gas) process.

https://doi.org/10.1590/1980-5373-mr-2022-0529

Deeper exploration of inflammatory cell populations in milk to monitor udder health in dairy cows
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Souza, Carolina Menezes Suassuna de

; Blagitz, Maiara Garcia

; Souza, Fernando Nogueira

; Batista, Camila Freitas

; Lima, Daniel Magalhães

; Alves, Alexandre José

; Heinemann, Marcos Bryan

; Sanchez, Eduardo Milton Ramos

; Torres, Hugo Frias

; Fernandes, Artur Cezar de Carvalho

; Libera, Alice Maria Melville Paiva Della

Scientia Agricola

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2023, Volume 80 elocation e20220086

Abstract: En | Text: En | PDF: En

ABSTRACT The present study explored the predictive values of milk leukocyte differentials (MLD) as a basis for improving the diagnosis of intramammary infections (IMIs) and subclinical mastitis. Quarter milk samples were collected for bacteriological analysis, quarter somatic cell count (qSCC), and MLD. The MLD were assessed using the cytospin technique, direct microscopic smears, and flow cytometry. The predictive values of each single leukocyte population and useful potential indices that could better reflect immune complexity were also calculated. Changes in the percentage of any leukocyte alone failed to substantially improve the predictive value of qSCC in diagnosing IMIs. Although certain parameters increased the area under the receiver operating characteristic curve (ROC curve) as a result of increased specificity values, a slight reduction in sensitivity was observed. The so-called CD8 complex was a unique parameter which improved both the sensitivity (78.79 %) and the specificity (80.77 %) in IMI diagnosis, resulting in the highest area under the ROC curve (0.87). To diagnose subclinical mastitis, the percentage of macrophages and the sum of the percentage PMNLs and T CD8+ cells divided by the percentage of macrophages showed the highest predictive values (sensitivity = 79.63, specificity = 73.68, and area under the ROC curve = 0.83) in the differentiation of the inflammatory condition status of cows. In conclusion, this study provides further insights into using T CD8+ lymphocytes in diagnosing bovine IMIs, combined with PMNLs and macrophages. The antidromic trend of macrophages vs. PMNLs and T CD8+ lymphocytes due to the increasing qSCCs was crucial to differentiating quarters under both inflammatory and non-inflammatory conditions.

https://doi.org/10.1590/1678-992x-2022-0086

PREOPERATIVE CHEMOTHERAPY VERSUS UPFRONT SURGERY FOR ADVANCED GASTRIC CANCER: A PROPENSITY SCORE MATCHING ANALYSIS
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Hong, Stefany

; Pereira, Marina Alessandra

; Victor, Carolina Ribeiro

; Gregório, João Vitor Antunes

; Zilberstein, Bruno

; Ribeiro Junior, Ulysses

; D'albuquerque, Luiz Augusto Carneiro

; Ramos, Marcus Fernando Kodama Pertille

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2023, Volume 36 elocation e1736

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND: Surgical resection remains the main curative therapeutic modality for advanced gastric cancer. Recently, the association of preoperative chemotherapy has allowed the improvement of results without increasing surgical complications. AIMS: To evaluate the surgical and oncological outcomes of preoperative chemotherapy in a real-world setting. METHODS: A retrospective review of gastric cancer patients who underwent gastrectomy was performed. Patients were divided into two groups for analysis: upfront surgery and preoperative chemotherapy. The propensity score matching analysis, including 9 variables, was applied to adjust for potential confounding factors. RESULTS: Of the 536 patients included, 112 (20.9%) were referred for preoperative chemotherapy. Before the propensity score matching analysis, the groups were different in terms of age, hemoglobin level, node metastasis at clinical stage- status, and extent of gastrectomy. After the analysis, 112 patients were stratified for each group. Both were similar for all variables assigned in the score. Patients in the preoperative chemotherapy group had less advanced postoperative p staging (p=0.010), postoperative n staging (p<0.001), and pTNM stage (p<0.001). Postoperative complications, 30- and 90-days mortality were similar between both groups. Before the propensity score matching analysis, there was no difference in survival between the groups. After the analysis, patients in the preoperative chemotherapy group had better overall survival compared to upfront surgery group (p=0.012). Multivariate analyses demonstrated that American Society of Anesthesiologists III/IV category and the presence of lymph node metastasis were factors significantly associated with worse overall survival. CONCLUSIONS: Preoperative chemotherapy was associated with increased survival in gastric cancer. There was no difference in the postoperative complication rate and mortality compared to upfront surgery.

RESUMO RACIONAL: A ressecção cirúrgica continua sendo a principal modalidade terapêutica curativa para o câncer gástrico avançado. Recentemente, a associação de quimioterapia pré-operatória tem permitido a melhora dos resultados sem aumentar as complicações cirúrgicas. OBJETIVOS: Avaliar os resultados cirúrgicos e oncológicos da quimioterapia pré-operatória em um cenário do mundo real. MÉTODOS: Realizou-se uma revisão retrospectiva de pacientes com câncer gástrico submetidos à gastrectomia. Os pacientes foram divididos em dois grupos para análise: cirurgia inicial e quimioterapia pré-operatória. A análise por escore de propensão, incluindo 9 variáveis, foi aplicada para ajustar possíveis fatores de confusão. RESULTADOS: Dos 536 pacientes incluídos, 112 (20,9%) foram encaminhados para quimioterapia pré-operatória. Antes da análise por escore de propensão, os grupos eram diferentes em termos de idade, nível de hemoglobina, status de node metastasis at clinical stage e extensão da gastrectomia. Após a análise, 112 pacientes foram estratificados para cada grupo. Ambos foram semelhantes para todas as variáveis atribuídas no escore. O grupo da quimioterapia pré-operatória apresentou estágios postoperative p staging (p=0,010), postoperative n staging (p<0,001) e pTNM menos avançados (p<0,001). As complicações pós-operatórias e a mortalidade em 30 e 90 dias foram semelhantes entre os grupos. Antes da análise por escore de propensão, não houve diferença na sobrevida entre os dois grupos. Após a análise, o grupo da quimioterapia pré-operatória apresentou melhor sobrevida global em comparação ao grupo da cirurgia inicial (p=0,012). As análises multivariadas demostraram que a categoria American Society of Anesthesiologists III/IV e a metástase linfonodal foram fatores significativamente associados à pior sobrevida global. CONCLUSÕES: A quimioterapia pré-operatória foi associada à maior sobrevida no câncer gástrico. Não houve diferença na taxa de complicações pós-operatórias e mortalidade em comparação com a cirurgia inicial.

https://doi.org/10.1590/0102-672020230018e1736

COVID-19 in the Perioperative Period of Cardiovascular Surgery: An Institutional Report
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Frisso, Luisa Schilmann

; Ramos, Ana Carolina Simões

; Sassine, Assad Miguel

Brazilian Journal of Cardiovascular Surgery

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2023, Volume 38 N. 4 elocation e20220253

Abstract: En | Text: En | PDF: En

https://doi.org/10.21470/1678-9741-2022-0253

10.

Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas – 2023
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Marin-Neto, José Antonio

; Rassi Jr, Anis

; Oliveira, Gláucia Maria Moraes

; Correia, Luís Claudio Lemos

; Ramos Júnior, Alberto Novaes

; Luquetti, Alejandro Ostermayer

; Hasslocher-Moreno, Alejandro Marcel

; Sousa, Andréa Silvestre de

; Paola, Angelo Amato Vincenzo de

; Sousa, Antônio Carlos Sobral

; Ribeiro, Antonio Luiz Pinho

; Correia Filho, Dalmo

; Souza, Dilma do Socorro Moraes de

; Cunha-Neto, Edecio

; Ramires, Felix Jose Alvarez

; Bacal, Fernando

; Nunes, Maria do Carmo Pereira

; Martinelli Filho, Martino

; Scanavacca, Maurício Ibrahim

; Saraiva, Roberto Magalhães

; Oliveira Júnior, Wilson Alves de

; Lorga-Filho, Adalberto Menezes

; Guimarães, Adriana de Jesus Benevides de Almeida

; Braga, Adriana Lopes Latado

; Oliveira, Adriana Sarmento de

; Sarabanda, Alvaro Valentim Lima

; Pinto, Ana Yecê das Neves

; Carmo, Andre Assis Lopes do

; Schmidt, Andre

; Costa, Andréa Rodrigues da

; Ianni, Barbara Maria

; Markman Filho, Brivaldo

; Rochitte, Carlos Eduardo

; Macêdo, Carolina Thé

; Mady, Charles

; Chevillard, Christophe

; Virgens, Cláudio Marcelo Bittencourt das

; Castro, Cleudson Nery de

; Britto, Constança Felicia De Paoli de Carvalho

; Pisani, Cristiano

; Rassi, Daniela do Carmo

; Sobral Filho, Dário Celestino

; Almeida, Dirceu Rodrigues de

; Bocchi, Edimar Alcides

; Mesquita, Evandro Tinoco

; Mendes, Fernanda de Souza Nogueira Sardinha

; Gondim, Francisca Tatiana Pereira

; Silva, Gilberto Marcelo Sperandio da

; Peixoto, Giselle de Lima

; Lima, Gustavo Glotz de

; Veloso, Henrique Horta

; Moreira, Henrique Turin

; Lopes, Hugo Bellotti

; Pinto, Ibraim Masciarelli Francisco

; Ferreira, João Marcos Bemfica Barbosa

; Nunes, João Paulo Silva

; Barreto-Filho, José Augusto Soares

; Saraiva, José Francisco Kerr

; Lannes-Vieira, Joseli

; Oliveira, Joselina Luzia Menezes

; Armaganijan, Luciana Vidal

; Martins, Luiz Cláudio

; Sangenis, Luiz Henrique Conde

; Barbosa, Marco Paulo Tomaz

; Almeida-Santos, Marcos Antonio

; Simões, Marcos Vinicius

; Yasuda, Maria Aparecida Shikanai

; Moreira, Maria da Consolação Vieira

; Higuchi, Maria de Lourdes

; Monteiro, Maria Rita de Cassia Costa

; Mediano, Mauro Felippe Felix

; Lima, Mayara Maia

; Oliveira, Maykon Tavares de

; Romano, Minna Moreira Dias

; Araujo, Nadjar Nitz Silva Lociks de

; Medeiros, Paulo de Tarso Jorge

; Alves, Renato Vieira

; Teixeira, Ricardo Alkmim

; Pedrosa, Roberto Coury

; Aras Junior, Roque

; Torres, Rosalia Morais

; Povoa, Rui Manoel dos Santos

; Rassi, Sergio Gabriel

; Alves, Silvia Marinho Martins

; Tavares, Suelene Brito do Nascimento

; Palmeira, Swamy Lima

; Silva Júnior, Telêmaco Luiz da

; Rodrigues, Thiago da Rocha

; Madrini Junior, Vagner

; Brant, Veruska Maia da Costa

; Dutra, Walderez Ornelas

; Dias, João Carlos Pinto

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 6 elocation e20230269

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20230269

11.

Seroprevalence of SARS-CoV-2 antibodies in schoolchildren in the city of São Paulo, 2020
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Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Albuquerque, José Olimpio Moura de

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Sato, Ana Paula Sayuri

; Glasser, Paula Regina

; Pino, Francisco Alberto

; Burihan, Patrícia Carla Piragibe Ramos

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Cavazzana, Cinthya Luzia

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Caldeira, Luiz Artur Vieira

; Silva, Solange Maria Saboia e

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Mauro, Athenê Maria de Marco França

; Masi, Eduardo de

Revista de Saúde Pública

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2023, Volume 57 Suppl. 1 elocation 6s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Estimar a soroprevalência de anticorpos do vírus SARS-CoV-2 em escolares de quatro a 14 anos de idade residentes no município de São Paulo, segundo variáveis clínicas, demográficas, epidemiológicas e sociais, durante o período de fechamento das escolas como medida de controle da covid-19. MÉTODOS Realizou-se um inquérito sorológico em setembro de 2020 com amostra aleatória estratificada por tipo de rede de ensino (pública municipal, pública estadual e privada). Foi coletada amostra de sangue venoso utilizando-se o teste de imunoensaio de fluxo lateral da fabricante Wondfo para detecção de anticorpos totais contra o vírus SARS-CoV-2. Aplicaram-se questionários semiestruturados para o levantamento de dados clínicos, demográficos, sociais e epidemiológicos. RESULTADOS A soroprevalência de anticorpos do vírus SARS-CoV-2 em escolares foi de 16,6% (IC95% 15,4–17,8). O estudo encontrou soroprevalências mais elevadas na rede pública municipal (18,5%; IC95% 16,6–20,6) e estadual (16,2%; IC95% 14,4–18,2) em relação à rede privada (11,7; IC95% 10,0–13,7) e entre escolares da raça/cor preta e parda (18,4%; IC95% 16,8–20,2) e no estrato social mais vulnerável (18,5%; IC95% 16,9–20,2). A pesquisa identificou menores soroprevalências nos escolares que relataram seguir as medidas recomendadas de proteção contra a covid-19. CONCLUSÃO A soroprevalência de anticorpos contra o vírus SARS-CoV-2 atinge principalmente os escolares socialmente mais vulneráveis. Este estudo pode contribuir para embasar políticas públicas que reforcem a importância da suspensão das aulas presenciais e da necessidade de estratégias de medidas de proteção e acompanhamento do status sorológico daqueles que ainda não foram contemplados no calendário vacinal.

ABSTRACT OBJECTIVE To estimate seroprevalence of SARS-CoV-2 antibodies in schoolchildren aged 4 to 14 years living in the city of São Paulo, according to clinical, demographic, epidemiological, and social variables, during the school closure period as a measure against covid-19 spread. METHODS A serological survey was made in September 2020 with a random sample stratified by school system (municipal public, state public and private) type. A venous blood sample was collected using the Wondfo SARS-CoV-2 Antibody Test (lateral flow method) for detection of total SARS-CoV-2 virus antibodies. Semi-structured questionnaires were applied to collect clinical, demographic, social, and epidemiological data. RESULTS Seroprevalence of SARS-CoV-2 antibodies in schoolchildren was of 16.6% (95%CI 15.4–17.8). The study found higher seroprevalence in the municipal (18.5%; 95%CI 16.6–20.6) and state (16.2%; 95%CI 14.4–18.2) public school systems compared to the private school system (11.7; 95%CI 10.0–13.7), among black and brown students (18.4%; 95%CI 16.8–20.2) and in the most vulnerable social stratum (18.5 %;95%CI 16.9–20.2). Lower seroprevalence was identified in schoolchildren who reported following the recommended protective measures against covid-19. CONCLUSION Seroprevalence of SARS-CoV-2 antibodies is found mainly in the most socially vulnerable schoolchildren. This study can contribute to support public policies that reinforce the importance of suspending face-to-face classes and developing strategies aimed at protective measures and monitoring of the serological status of those who have not yet been included in the vaccination schedule.

https://doi.org/10.11606/s1518-8787.2023057004782

12.

Seroprevalence of SARS-CoV-2 antibodies in schoolchildren in the city of São Paulo, 2020
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Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Albuquerque, José Olimpio Moura de

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Sato, Ana Paula Sayuri

; Glasser, Paula Regina

; Pino, Francisco Alberto

; Burihan, Patrícia Carla Piragibe Ramos

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Cavazzana, Cinthya Luzia

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Caldeira, Luiz Artur Vieira

; Silva, Solange Maria Saboia e

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Mauro, Athenê Maria de Marco França

; Masi, Eduardo de

Revista de Saúde Pública

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2023, Volume 57 elocation 6s

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.11606/s1518-8787.2023057004782

13.

Economic evaluations of colorectal cancer screening: A systematic review and quality assessment
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Ramos, Marcela Castro

; Passone, Julio Augusto de Lima

; Lopes, Ana Carolina de Freitas

; Safatle-Ribeiro, Adriana Vaz

; Ribeiro Júnior, Ulysses

; Soárez, Patrícia Coelho de

Clinics

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2023, Volume 78 elocation 100203

Abstract: En | Text: En | PDF: En

Abstract Colorectal Cancer (CRC) is the third most common type of cancer worldwide and ranks second in mortality. Screening programs for early detection and treatment have been implemented in several countries. Economic evaluations are an important tool to support decision-making about reimbursement and coverage decisions in health systems and, therefore, to support efficient resource allocation. The article aims to review the up-to-date evidence on economic evaluations of CRC screening strategies. MEDLINE, EMBASE, Web of Science, SCOPUS, SciELO, Lilacs, CRD databases, and lists of references were reviewed to identify relevant literature regarding full economic evaluations of CRC screening in asymptomatic average-risk individuals over 40 years old. Searches were conducted with no restriction to language, setting, or date. Qualitative syntheses described CRC screening strategies and comparators (baseline context), study designs, key parameter inputs and incremental cost-effectiveness ratios. Seventy-nine articles were included. Most of the studies were from high-income countries and a third-party payer perspective. Markov models were predominantly used, although microsimulation has been increasingly adopted in the last 15 years. The authors found 88 different screening strategies for CRC, which differed in the type of technique, the interval of screening, and the strategy, i.e., isolated or combined. The annual fecal immunochemical test was the most predominant screening strategy. All studies reported cost-effective results in their scenarios compared to no screening scenarios. One-quarter of the publications reported cost-saving results. It is still necessary to develop future economic evaluations in Low- and Middle-Income Countries (LMICs), which account for the high burden of disease.

https://doi.org/10.1016/j.clinsp.2023.100203

14.

Nivel de conocimiento de antioxidantes y su relación con el estilo de vida
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Gutiérrez-Ramos, Miriam Elizabeth

; Rodriguez-Saavedra, Lennin Roswell

; Alva-Plasencia, Pedro Marcelo

; Abanto-Zamora, Francisco Moisés

; Chávez-Abanto, Luis Alberto

; Saavedra-Suárez, Segundo Francisco

Memorias del Instituto de Investigaciones en Ciencias de la Salud

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2023, Volume 21 N. 1 elocation e21122302

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The objective of this study was to determine the level of knowledge about antioxidants and their relationship with lifestyle. A descriptive, cross-sectional study with the participation of 392 inhabitants of the city of Trujillo, who responded to two questionnaires: one to determine the level of knowledge about antioxidants prepared by Dr. Carolina Gonzalez, a nutritionist from Clínica Alemana, consisting of five questions related to antioxidants, and the other questionnaire of lifestyle promotes health elaborated by Walker, Sechrist and Pender, and modified by Delgado, R; Reyna E and Diaz, R constituted by 25 questions, obtaining information on knowledge of antioxidants and nutrition, exercise and activity, stress. With the obtained data the respective qualification and the healthy and unhealthy score scale and has knowledge or not was obtained. From the processed surveys, there was evidence of a higher percentage of people who had no knowledge of antioxidants 222 (56.64%) with a predominance of young people 141 (35.97%), as well as an unhealthy lifestyle 285 (72.71%). There was a relationship between the level of antioxidant knowledge and sex but there was no relationship with respect to age. In addition, there was no relationship between the variables sex and age with lifestyle, taking into account that if P > 0.05 there is no relationship or significant difference. Finally, we can conclude that the study population had no knowledge of antioxidants and inadequate lifestyle.

RESUMEN El presente estudio tiene por objetivo determinar el nivel de conocimiento respecto a los antioxidantes y su relación con el estilo de vida. Estudio descriptivo, de corte transversal con la participación de 392 pobladores de la ciudad de Trujillo, que dieron respuesta a dos cuestionarios: uno para determinar el nivel de conocimiento respecto a los antioxidantes elaborado por la Dra. Carolina González, nutrióloga de la Clínica Alemana, que consta de cinco preguntas relacionadas a los antioxidantes y el cuestionario de estilo de vida promueve la salud elaborado por Walker, Sechrist y Pender, y modificado por Delgado, R; Reyna E y Diaz, R constituido por 25 preguntas, obteniendo información sobre conocimiento de antioxidantes y alimentación, ejercicio y actividad, estrés. Con los datos obtenidos se obtuvo la calificación respectiva y la escala de puntuación saludable y no saludable y si tiene conocimiento o no. De las encuestas procesadas, se evidenció mayor porcentaje de pobladores que no tenían conocimiento de antioxidantes 222 (56.64%) con predominio de los jóvenes 141 (35.97%), así como de un estilo de vida no saludable 285 (72.71%). Se presentó una relación entre nivel de conocimiento de antioxidantes y sexo, con la edad no hubo relación. Además, no hubo relación entre las variables sexo y edad con estilo de vida, teniendo en cuenta que si P > 0.05 no hay relación o diferencia significativa. Finalmente podemos concluir que la población en estudio no tenía conocimiento sobre antioxidantes y estilo de vida no adecuado.

https://doi.org/10.18004/mem.iics/1812-9528/2023.e21122302

15.

Diagnostic performance of anthropometric indicators used to assess excess body fat in adolescence
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Antunes, Nelma Maria Neves

; Silveira, Marise Fagundes

; Silva, Rosângela Ramos Veloso

; Rocha, Josiane Santos Brant

; Oliveira, Fernanda Piana Santos Lima de

; Ruas, Sélen Jaqueline Souza

; Borborema, Fabiana Aparecida Maia

; Duarte, Jose Henrique Pinto

; Rodrigues, Carolina Amaral Oliveira

; Brito, Maria Fernanda Santos Figueiredo

; Caldeira, Antônio Prates

; Pinho, Lucinéia de

Revista Paulista de Pediatria

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2023, Volume 41 elocation e2021189

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Comparar o desempenho de indicadores antropométricos para identificar o excesso de gordura corporal (GC) em adolescentes. Métodos: Estudo metodológico com amostragem probabilística por conglomerados, por sorteio das escolas e turmas. A coleta de dados incluiu características sociodemográficas e medidas antropométricas. O índice de massa corporal (IMC), a relação cintura-estatura (RCE), o índice de conicidade (IC) e a circunferência da cintura (CC) foram calculados. O percentual de gordura corporal (%GC) foi calculado com base na espessura das dobras cutâneas e utilizado como padrão-ouro. Para analisar os dados, foram utilizadas estatísticas descritivas, teste t de Student, curva Receiver Operating Characteristic (ROC) e índice de Youden. Foi calculado o coeficiente de correlação entre os indicadores e o %GC. Resultados: Participaram do estudo 997 adolescentes de escolas municipais. Identificou-se, pelo IMC, que 10,6% dos adolescentes apresentavam sobrepeso e 4,7%, obesidade. O IMC, a CC e a RCE apresentaram a maior acurácia para predizer a gordura corporal. Todos os indicadores antropométricos apresentaram especificidade superior à sensibilidade para diagnosticar excesso de GC no sexo masculino. A CC apresentou a maior sensibilidade em ambos os sexos. O IC apresentou a menor área sob a curva ROC e a menor sensibilidade em ambos os sexos, mas especificidade equivalente aos demais indicadores. Conclusões: IMC, RCE e CC apresentaram a melhor capacidade de predizer excesso de GC em adolescentes e os melhores coeficientes de correlação. Essas ferramentas podem ser consideradas formas de rastreamento na identificação do excesso de GC em adolescentes.

Abstract Objective: To compare the performance of anthropometric indicators that identify excess body fat (BF) in adolescents. Methods: This is a methodological study that used probability cluster sampling through school and class draws. Data collection included sociodemographic characteristics and anthropometric measures. Body mass index (BMI), waist-to-height ratio (WtHR), conicity index (C index), and waist circumference (WC) were calculated. Body fat percentage (BF%) was calculated from skinfold thickness and used as the gold standard. To analyze the data, descriptive statistics, Student’s t-test, Receiver Operating Characteristic (ROC) curve, and Youden’s index were used, in addition to correlation coefficient calculation between the indicators and BF%. Results: A total of 997 adolescents enrolled in municipal secondary schools participated in the study. By calculating the BMI, we found that 10.6% of adolescents were overweight, and 4.7% were obese. BMI, WC, and WtHR had the highest accuracy to predict body fatness. All the anthropometric indicators had higher specificity than sensitivity to diagnose excess BF in males. WC had the highest sensitivity in both genders. C index had the smallest area under the ROC curve and the lowest sensitivity in both genders, but its specificity was equivalent to that of the other indicators. Conclusions: BMI, WtHR, and WC were the best anthropometric indicators to predict excess BF in adolescents and had the best correlation coefficients. These tools can be considered in the screening to detect excess BF in adolescents.

https://doi.org/10.1590/1984-0462/2023/41/2021189

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