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Tendência da mortalidade por tuberculose e relação com o índice sociodemográfico no Brasil entre 2005-2019
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Queiroz, Juliana Rodrigues de

; Vieira, Nayara Figueiredo

; Oliveira, Michele Dias da Silva

; Maia, Ludmila Grego

; Figueiredo, Rogério Carvalho de

; Gonzalez, Roxana Isabel Cardozo

; Guimarães, Rafael Alves

Ciência & Saúde Coletiva

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2024, Volume 29 N. 5 elocation e00532023

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo do artigo é analisar a tendência da taxa de mortalidade padronizada (TMP) por tuberculose e sua correlação com o status de desenvolvimento no Brasil. Estudo ecológico de séries temporais que analisou dados de óbitos por tuberculose notificados entre 2005 e 2019 de todos os estados. Os dados foram extraídos do Sistema de Informação sobre Mortalidade, do Instituto Brasileiro de Geografia e Estatística e do estudo da Carga Global de Doenças. A tendência temporal foi analisada pela regressão de Prais-Winsten. A análise da correlação de Spearman entre a TMP e o índice sociodemográfico (socio-demographic index - SDI) também foi realizada. De 2005 a 2019, foram registrados 68.879 óbitos por tuberculose no Brasil. A taxa média de mortalidade foi de 2,3 óbitos por 100.000 habitantes. A tendência decrescente da TMP por tuberculose foi observada no Brasil e em todas as regiões. Verificou-se correlação negativa significativa entre o SDI e a TMP. A maioria dos estados apresentou tendência decrescente e nenhum deles teve tendência crescente. Uma relação inversa foi verificada entre o SDI e a mortalidade por tuberculose.

Abstract The scope of this article is to analyze the trend of the standardized mortality rate (SMR) for tuberculosis and its correlation with the developmental status in Brazil. An ecological time series study was conducted to analyze data of deaths from tuberculosis reported between 2005 and 2019 in all states. Data were extracted from the Mortality Information System, the Brazilian Institute of Geography and Statistics, and the Global Burden of Disease study. The temporal trend was analyzed using Prais-Winsten regression. Spearman’s correlation analysis between SMR and Socio-Demographic Index (SDI) was also performed. From 2005 to 2019, 68,879 deaths from tuberculosis were recorded in Brazil. The average mortality rate was 2.3 deaths per 100,000 inhabitants. The decreasing trend of SMR due to tuberculosis was observed in Brazil and in all regions. There was a significant negative correlation between SDI and TMP. TMP due to tuberculosis revealed a decreasing trend in Brazil and in all regions. Most states showed a decreasing trend and none of them had an increasing trend. An inverse relationship was found between developmental status and mortality due to tuberculosis.

https://doi.org/10.1590/1413-81232024295.00532023

O CUIDAR DO ADOLESCENTE COM OBESIDADE NA ATENÇÃO PRIMÁRIA À SAÚDE: PERSPECTIVAS DE GESTORES E PROFISSIONAIS
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Oliveira, Vinícius Rodrigues de

; Oliveira, Jonas Sâmi Albuquerque de

; Xavier, Bárbara Letícia de Queiroz

; Morais, Jéssica Baracho de Souza

; Araújo, Juliana Iscarlaty Freire de

; Soares, Amanda

; Freitas, Claudia Helena Soares de Morais

Cogitare Enfermagem

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2024, Volume 29 elocation e92118

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

RESUMO Objetivo: Descrever e explorar, sob a perspectiva de gestores e profissionais de saúde, o cuidado ofertado ao adolescente com obesidade no âmbito da Atenção Primária à Saúde. Método: Estudo de caso, realizado em município do estado do Ceará-Brasil. A coleta de dados ocorreu em 2022, por meio de entrevistas semiestruturadas. Os dados foram examinados através da Análise de conteúdo de Bardin. Resultados: O cuidado ao adolescente com obesidade é fragmentado, cada profissional atua conforme decisão própria, pois o município não utiliza protocolos que subsidiem a prática assistencial. Foram elencadas potencialidades para o cuidado, sendo a principal a equipe multiprofissional. Quanto às dificuldades, destacou-se a procura do serviço de saúde pelo adolescente. Conclusão: Faz-se necessária uma (re)organização do modelo de atenção ao adolescente com obesidade no município. Além disso, o estudo ressalta a necessidade de maior atenção a obesidade na adolescência e provoca reflexões acerca do cuidado dispensado a este adolescente.

RESUMEN Objetivo: Describir y explorar, desde la perspectiva de los gestores y profesionales sanitarios, la atención ofrecida a los adolescentes con obesidad en el ámbito de la Atención Primaria de Salud. Método: Estudio de caso, realizado en un municipio del estado de Ceará-Brasil. Los datos se recogieron en 2022 mediante entrevistas semiestructuradas. Los datos se analizaron mediante el análisis de contenido de Bardin. Resultados: La atención a los adolescentes con obesidad está fragmentada, y cada profesional actúa según su propia decisión, ya que el municipio no utiliza protocolos para subvencionar la práctica asistencial. Se enumeraron las potencialidades asistenciales, siendo la principal el equipo multiprofesional. En cuanto a las dificultades, se destaca la búsqueda del servicio sanitario por parte del adolescente. Conclusión: Es necesario (re)organizar el modelo de atención a los adolescentes con obesidad en el municipio. Además, el estudio pone de manifiesto la necesidad de prestar más atención a la obesidad en la adolescencia y suscita reflexiones sobre la atención prestada a este adolescente.

ABSTRACT Objective: Describe and explore, from the perspective of managers and health professionals, the care offered to adolescents with obesity in the context of Primary Health Care. Method: A case study conducted in a municipality in the state of Ceará-Brazil. Data collection took place in 2022 through semi-structured interviews. The data were examined using Bardin Content Analysis. Results: The care of obese adolescents is fragmented, and each professional acts according to their own decision, as the municipality does not use protocols that subsidize the practice of care. Potentials for care were listed, the main one being the multidisciplinary team. Regarding the difficulties, the adolescent’s demand for health services was highlighted. Conclusion: It is necessary to (re) organize the care model for obese adolescents in the municipality. In addition, the study highlights the need for greater attention to adolescent obesity and causes reflections on the care provided to this adolescent.

https://doi.org/10.1590/ce.v29i0.92118

Tendência da mortalidade por tuberculose e relação com o índice sociodemográfico no Brasil entre 2005-2019
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Queiroz, Juliana Rodrigues de

; Vieira, Nayara Figueiredo

; Oliveira, Michele Dias da Silva

; Maia, Ludmila Grego

; Figueiredo, Rogério Carvalho de

; Gonzalez, Roxana Isabel Cardozo

; Guimarães, Rafael Alves

Ciência & Saúde Coletiva

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2024, Volume 29 N. 5 elocation e00532023

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232024295.00532023

Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders guidelines for the treatment of adult obsessive-compulsive disorder. Part II: cognitive-behavioral therapy
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Mathis, Maria Alice de

; Chacon, Priscila

; Boavista, Rodrigo

; de Oliveira, Marcos Vinícius Sousa

; de Barros, Pedro Macul Ferreira

; Echevarria, Marco Antonio Nocito

; Ferrão, Ygor Arzeno

; Vattimo, Edoardo Filippo de Queiroz

; Lopes, Antônio Carlos

; Torres, Albina Rodrigues Diniz, Juliana Belo Fontenelle, Leonardo do Rosário, Maria Conceição Shavitt, Roseli Gedanke da Silva, Renata de Melo Felipe Miguel, Eurípedes Constantino Costa, Daniel Lucas da Conceição

Brazilian Journal of Psychiatry

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oct 2023, Volume 45 N. 5 Pages 431 - 447

Abstract: En | Text: En | PDF: En

Objectives: To summarize evidence-based cognitive-behavioral therapy (CBT) treatment and propose clinical interventions for adult patients with obsessive-compulsive disorder (OCD). Methods: The literature on CBT interventions for adult OCD, including BT and exposure and response prevention, was systematically reviewed to develop updated clinical guidelines for clinicians, providing comprehensive details about the necessary procedures for the CBT protocol. We searched the literature from 2013-2020 in five databases (PubMed, Cochrane, Embase, PsycINFO, and Lilacs) regarding study design, primary outcome measures, publication type, and language. Selected articles were assessed for quality with validated tools. Treatment recommendations were classified according to levels of evidence developed by the American College of Cardiology and the American Heart Association. Results: We examined 44 new studies used to update the 2013 American Psychiatric Association guidelines. High-quality evidence supports CBT with exposure and response prevention techniques as a first-line treatment for OCD. Protocols for Internet-delivered CBT have also proven efficacious for adults with OCD. Conclusion: High-quality scientific evidence supports the use of CBT with exposure and response prevention to treat adults with OCD.

https://doi.org/10.47626/1516-4446-2023-3081

Rainfall variability affects the chemical composition, gas production and degradability of cacti
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Ribeiro Menezes, Daniel

; Muniz dos Santos, Juliana

; Nunes de Oliveira, Cintia Raquel

; Rodrigues Marcelino, Polyana Deyse

; da Mata Araújo Pinheiro, Anna Paula

; Queiroz de Carvalho, Dalinne Tamara

; Silva Nascimento, Júlio Cesar

; Costa Gois, Glayciane

; Vinhas Voltolini, Tadeu

; Ávila Queiroz, Mario Adriano

Revista colombiana de ciencia animal recia

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jun 2022, Volume 14 N. 1 elocation 05

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Objetivo. El objetivo fue evaluar el efecto de la variabilidad de las lluvias sobre la composición química, la degradabilidad in vitro y la producción de gas de cactus en la región Semiárida. Materiales y métodos. Este fue un diseño experimental completamente al azar en un arreglo factorial de 2 períodos de lluvia (lluvia alta y baja) x 5 especies de cactus, con 5 repeticiones. Los cactus evaluados fueron Pilosocereus gounellei (Weber ex K. Schum). Bly ex Rowl, Cereus jamacaru DC., Opuntia ficus indica Mill, Nopalea cochenillifera Salm. Dyck y Opuntia stricta (Haw.) Haw, todas frescas. Resultados. Hubo una interacción entre la variación de la lluvia y las especies de cactus para materia seca, proteína cruda, fibra detergente neutra y fibra detergente ácido (p<0.05), producción de gas in vitro (p<0.05) y para la degradabilidad in vitro de materia seca (p<0.05). Entre los cactus, Pilosocereus gounellei presentó una menor proporción de materia orgánica y un aumento en el contenido de materia mineral en relación a los demás cactus (p<0.05). Conclusiones. La composición química, los coeficientes de producción de gas y la degradabilidad in vitro fueron influenciados por las especies de cactus y por la variación de las precipitaciones. Las especies de cactus aumentan el contenido de materia seca, proteína cruda y fibra de detergente neutro durante la escasez de precipitaciones. Las variedades de nopal (Opuntia y Nopalea) se destacaron entre los cactus ensayados en relación a la producción de gas y la degradabilidad in vitro.

ABSTRACT Objective. The objective was to evaluate the effect of rainfall variability on the chemical composition, in vitro degradability and gas production of cacti in Semiarid region. Materials and methods. A completely randomized experimental design in a factorial arrangement of 2 rainfall periods (high and low rainfall) x 5 cactus species, with 5 replications was adopted. Cacti evaluated were Pilosocereus gounellei (Weber ex K. Schum). Bly ex Rowl, Cereus jamacaru DC., Opuntia ficus indica Mill, Nopalea cochenillifera Salm. Dyckand Opuntia stricta (Haw.) Haw, all fresh. Results. There was an interaction between rainfall variation and cactus species for dry matter, crude protein, neutral detergent fiber and acid detergent fiber (p<0.05), in vitro gas production (p<0.05) and for in vitro dry matter degradability (p<0.05). Among cacti, Pilosocereus gounellei presented a lower proportion of organic matter and an increase in the content of mineral matter in relation to the other cacti (p<0.05). Conclusions. The chemical composition, the gas production coefficients and the in vitro degradability were influenced by the cacti species and by the rainfall variation. Cacti species increase the dry matter, crude protein and neutral detergent fiber contents during the low rainfall. Varieties of cactus pear (Opuntia and Nopalea) stood out among the cacti tested in relation to gas production and in vitro degradability.

https://doi.org/10.24188/recia.v14.n1.2022.895

Relationship between BsmI polymorphism and VDR gene methylation profile, gender, metabolic profile, oxidative stress, and inflammation in adolescents
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Lucena, Lavoisiana Lacerda de Silva, Alexandre Sérgio Nascimento, Rayner Anderson Ferreira do Persuhn, Darlene Camati Neves, Juliana Padilha Ramos Costa, Maria José de Carvalho Queiroz, Dayanna Joyce Marques Cavalcanti de Lima, Rafaela Lira Formiga Lima, Raquel Patrícia Ataíde Paiva, Maria Paula de Oliveira, Naila Francis Paulo de Gonçalves, Maria da Conceição Rodrigues

Nutrición Hospitalaria

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oct 2021, Volume 38 N. 5 Pages 911 - 918

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: la actividad biológica de la vitamina D depende de la actividad de su receptor, el VDR. Por otro lado, la actividad de este receptor está influenciada por su estado de metilación. El objetivo de este estudio es verificar si el polimorfismo BsmI del gen VDR influye en el perfil de metilación del mismo en los adolescentes. En segundo lugar, verificar si los factores metabólicos (estrés oxidativo, inflamación, perfil lipídico y glucemia) del suero y la vitamina D ajustada por sexo actúan independientemente de los polimorfismos sobre el perfil de metilación del VDR. Métodos y resultados: el estudio incluyó a 198 adolescentes de ambos sexos, de 15 a 19 años de edad, que se sometieron a análisis de polimorfismos de metilación del gen VDR, niveles de vitamina D, marcadores metabólicos, estrés oxidativo e inflamación sistémica. Se observó que el genotipo BB estaba menos metilado que los otros grupos (26,1 % contra 30,3 % y 29,3 % para Bb y bb respectivamente), aunque sin diferencias estadísticas entre ellos. El odds ratio indicó una protección del 13 % (parcialmente metilado) para el estado de la vitamina D, mientras que los alfa glicoles aumentaron el índice de riesgo (de estar parcialmente metilado) en un 3 %. La MDA fue protectora con un 28 % de probabilidad de riesgo de que los adolescentes con niveles más altos de peroxidación lipídica fueran hipometilados. Conclusión: concluimos que el perfil de metilación del gen VDR no está influenciado por los diferentes genotipos del polimorfismo BsmI y que la vitamina D y los marcadores de estrés oxidativo e inflamación en el suero pueden modular este perfil.

Abstract Background: the biological activity of vitamin D depends on the activity of its receptor or VDR. On the other hand, the activity of this receptor is influenced by its state of methylation. The objective of this study was to verify if the BsmI polymorphism of the VDR gene influences its methylation profile in adolescents. Secondly, it was to verify if the status of some metabolic factors (oxidative stress, inflammation, lipid profile, and glycemia) in the serum, and gender-adjusted vitamin D levels are independent factors with an influence on the VDR methylation profile. Methods and results: the study included 198 adolescents of both sexes, aged 15-19 years, who underwent testing for VDR gene methylation polymorphisms, serum vitamin D levels, and metabolic, oxidative stress, and systemic inflammation markers. It was observed that the BB genotype was less methylated than the other groups (26.1 % versus 30.3 %, and 29.3 % for Bb and bb, respectively), although without statistical differences between them. The odds ratio indicated a protection of 13 % (partially methylated) for vitamin D status, while alpha glycols increased the risk ratio (of being partially methylated) by 3 %. MDA was protective at a 28 % chance of risk that adolescents with higher levels of lipid peroxidation would be hypomethylated. Conclusion: we conclude that the methylation profile of the VDR gene is not influenced by the different BsmI polymorphism genotypes, and that serum vitamin D and serum markers of oxidative stress and inflammation can modulate this profile.

https://doi.org/10.20960/nh.03383

Variants rs1544410 and rs2228570 of the vitamin D receptor gene and glycemic levels in adolescents from Northeast Brazil
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Neves, Juliana Padilha Ramos Queiroz, Dayanna Joyce Marques Araújo, Eduarda Pontes dos Santos Lucena, Lavoisiana Lacerda de Nascimento, Rayner Anderson Ferreira do Carvalho, Alice Teles de Costa, Maria José de Carvalho França, Ana Karina Teixeira da Cunha Persuhn, Darlene Camati Silva, Alexandre Sérgio Diniz, Alcides da Silva Gonçalves, Maria da Conceição Rodrigues

Nutrición Hospitalaria

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feb 2020, Volume 37 N. 1 Pages 21 - 27

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Objective: to verify the association of serum concentrations of 25-hydroxyvitamin D and glycemic levels with the genetic variants rs1544410 and rs2228570 of the VDR gene in adolescents from the Northeast region of Brazil. Materials and methods: a cross-sectional epidemiological study with 208 adolescents from public schools in the city of João Pessoa (Paraíba, Brazil) between 15 and 19 years of age. Blood samples were collected for DNA extraction and analysis of polymorphisms rs1544410 and rs2228570, as well as biochemical analyses (25-hydroxyvitamin D, parathyroid hormone, calcium and glycemia). Results: the mean age was 17.7 (± 1.14) years. Half of adolescents had sufficient serum levels of 25-hydroxyvitamin D and the other half had insufficient/deficient vitamin. The most frequent genotypic distribution was bb and Ff and of lesser frequency BB and ff. There was a significant relationship between the genotypes of rs1544410 and glycemia values (p = 0.049) in the relationships between the genotypes BBxbb (p = 0.012) and Bbxbb (p = 0.037); (p = 0.036, OR = 2.15, 95 % CI = 1.05-4.41), and in the BB+Bb group analysis when compared to the bb (p = 0.025, OR = 1.89, 95 % CI = 1.08-3.29) presented higher risk of glycemia above the median. On the other hand, when Bb+bb was analyzed in relation to BB, adolescents had a greater chance of blood glucose below the median (p = 0.025, OR = 0.66, CI = 0.47-0.95). Conclusion: this study showed a significant relation of glycemia with the distribution of rs1544410 polymorphism genotypes.

Resumen Objetivo: verificar la asociación de las concentraciones séricas de 25-hidroxivitamina D y los niveles de glucemia con las variantes genéticas rs1544410 y rs2228570 del gen VDR en adolescentes de la región noreste de Brasil. Materiales y métodos: se realizó un estudio epidemiológico transversal con 208 adolescentes de escuelas públicas en la ciudad de João Pessoa (Paraíba, Brasil) de entre 15 y 19 años de edad. Se recogieron muestras de sangre para la extracción de ADN y el análisis de los polimorfismos rs1544410 y rs2228570, así como para análisis bioquímicos (25-hidroxivitamina D, hormona paratiroidea, calcio y glucemia). Resultados: la edad media fue de 17,7 (± 1,14) años. La mitad de los adolescentes tenía niveles séricos suficientes de 25-hidroxivitamina D y la otra mitad, vitamina insuficiente/deficiente. La distribución genotípica más frecuente fue bb y Ff y la de menor frecuencia, BB y ff. Hubo una relación significativa entre los genotipos de rs1544410 y los valores de glucemia (p = 0,049) en las relaciones entre los genotipos BBxbb (p = 0,012) y Bbxbb (p = 0,037); (p = 0,036, OR = 2,15, IC 95 % = 1,05-4.41), y el análisis del grupo BB + Bb en comparación con el bb (p = 0,025, OR = 1,89, IC 95 % = 1,08-3,29) mostró un mayor el riesgo de glucemia, por encima de la mediana. Por otro lado, cuando se analizó Bb+bb en relación con la BB, los adolescentes tuvieron una mayor probabilidad de que la glucosa en sangre estuviera por debajo de la mediana (p = 0,025, OR = 0,66, IC = 0,47-0,95). Conclusión: este estudio mostró una relación significativa entre la glucemia y la distribución de genotipos de polimorfismo rs1544410.

https://doi.org/10.20960/nh.02587

Prevalence of hypovitaminosis D and associated factors in adolescent students of a capital of northeastern Brazil
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Pontes dos Santos Araújo, Eduarda Marques Queiroz, Dayanna Joyce Padilha Ramos Neves, Juliana Mateus de Lacerda, Lavoisiana Rodrigues Gonçalves, Maria da Conceição Teles de Carvalho, Alice

Nutrición Hospitalaria

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dec 2017, Volume 34 N. 6 Pages 1416 - 1423

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Background: Hypovitaminosis D is a frequent problem in the world and can be influenced by several factors. Objective: To estimate the prevalence of hypovitaminosis D and associated factors in adolescent students of a capital city of northeastern Brazil. Methods: Cross-sectional epidemiological study assessing 220 school adolescents of both sexes aged 15 to 19 years. A questionnaire was applied to assess sociodemographic (skin color, mother's education and receiving social benefits) and behavioral data (number of hours of sleep per day, sun exposure, physical activity and dietary vitamin D intake). Anthropometric nutritional status was assessed by BMI (body mass index) for age. Serum 25 (OH) D concentrations, PTH and serum calcium were measured by blood samples. We identified individuals with hypovitaminosis D as those with 25 (OH) D < 30 ng/dL. The analysis of factors associated with hypovitaminosis D was performed by simple and multivariate Poisson Regression. Results: The prevalence of hypovitaminosis D was 57.3%. The female population had a significantly higher prevalence than the male. In the final adjusted model, the variable independently associated with hypovitaminosis D in females was the lowest serum calcium concentrations, and for males it was BMI, in which adolescents who had overweight/obesity were 2.4 times more likely to have hypovitaminosis D than the eutrophic ones. Conclusions: The present study found a high prevalence of hypovitaminosis D in the analyzed population, especially in female adolescents. In addition, the factors independently associated with hypovitaminosis D were found to be overweight/obese in boys and low calcium concentrations in girls.

Introducción: la hipovitaminosis D es un problema frecuente en el mundo y puede verse influenciada por varios factores. Objetivo: estimar la prevalencia de hipovitaminosis D y factores asociados en adolescentes de una ciudad capital del noreste de Brasil. Métodos: estudio epidemiológico transversal que evaluó a 220 adolescentes de ambos sexos de 15 a 19 años de edad. Se aplicó un cuestionario para evaluar los datos sociodemográficos y de comportamiento. El estado nutricional antropométrico fue evaluado por IMC para la edad. Las concentraciones séricas de 25 (OH) D, PTH y calcio en suero se midieron mediante muestras de sangre. Se identificaron individuos con hipovitaminosis D como aquellos con 25 (OH) D < 30 ng/dl. El análisis de factores asociados con la hipovitaminosis D se realizó mediante Regresión de Poisson simple y multivariante. Resultados: la prevalencia de hipovitaminosis D fue del 57,3%. La población femenina tenía una prevalencia significativamente mayor que la masculina. En el modelo ajustado final, la variable independientemente asociada con la hipovitaminosis D en las mujeres fue la más baja de las concentraciones séricas de calcio, y para los hombres fue el IMC, en el que los adolescentes con sobrepeso/obesidad tenían 2,4 veces más probabilidades de tener hipovitaminosis que los eutróficos. Conclusiones: el presente estudio encontró una alta prevalencia de hipovitaminosis D en la población analizada, especialmente en adolescentes. Además, se encontró que los factores asociados de forma independiente con la hipovitaminosis D fueron el sobrepeso/obesidad en los niños y concentraciones bajas de calcio en las niñas.

https://doi.org/10.20960/nh.1097

ERICA: prevalence of metabolic syndrome in Brazilian adolescents
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Kuschnir, Maria Cristina C Bloch, Katia Vergetti Szklo, Moyses Klein, Carlos Henrique Barufaldi, Laura Augusta Abreu, Gabriela de Azevedo Schaan, Beatriz Veiga, Gloria Valeria da Silva, Thiago Luiz Nogueira da Vasconcellos, Maurício T L de Moraes, Ana Júlia Pantoja de Oliveira, Ana Mayra Andrade de Tavares, Bruno Mendes Oliveira, Cecília Lacroix de Cunha, Cristiane de Freitas Giannini, Denise Tavares Belfort, Dilson Rodrigues Santos, Eduardo Lima Leon, Elisa Brosina de Oliveira, Elizabete Regina Araújo Fujimori, Elizabeth Borges, Ana Luíza Magliano, Erika da Silva Vasconcelos, Francisco de Assis Guedes Azevedo, George Dantas Brunken, Gisela Soares Guimarães, Isabel Cristina Britto Faria Neto, José Rocha Oliveira, Juliana Souza Carvalho, Kenia Mara B de Gonçalves, Luis Gonzaga de Oliveira Monteiro, Maria Inês Santos, Marize M Muniz, Pascoal Torres Jardim, Paulo César B Veiga Ferreira, Pedro Antônio Muniz Montenegro Jr, Renan Magalhães Gurgel, Ricardo Queiroz Vianna, Rodrigo Pinheiro Vasconcelos, Sandra Mary Martins, Stella Maris Seixas Goldberg, Tamara Beres Lederer

Revista de Saúde Pública

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2016, Volume 50 Suppl. 1 elocation 11s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Determinar a prevalência de síndrome metabólica e de seus componentes em adolescentes brasileiros. MÉTODOS Foram avaliados 37.504 adolescentes, participantes do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA), estudo transversal de âmbito nacional e de base escolar. Os adolescentes, de 12 a 17 anos de idade, residiam em municípios com mais de 100 mil habitantes. A amostra foi estratificada e conglomerada em escolas e turmas. Os critérios da International Diabetes Federation foram utilizados para definir síndrome metabólica. Prevalências de síndrome metabólica foram estimadas segundo sexo, faixa etária, tipo de escola e estado nutricional. RESULTADOS Dos 37.504 adolescentes, 50,2% eram do sexo feminino; 54,3% tinham de 15 a 17 anos e 73,3% estudavam em escolas públicas. A prevalência nacional de síndrome metabólica foi 2,6% (IC95% 2,3-2,9), discretamente maior no sexo masculino e naqueles de 15 a 17 anos na maioria das macrorregiões. A prevalência foi a maior nos residentes na macrorregião Sul, nas adolescentes mais jovens e nos adolescentes mais velhos. A prevalência foi maior nas escolas públicas (2,8% [IC95% 2,4-3,2]) que nas escolas privadas (1,9% [IC95% 1,4-2,4]) e nos adolescentes obesos em comparação aos não obesos. As combinações de componentes mais frequentes, respondendo por 3/4 das combinações, foram: circunferência de cintura elevada, HDL-colesterol baixo e pressão arterial elevada, seguida de circunferência da cintura elevada, lipoproteína de alta densidade (HDL-c) baixo e triglicerídeos elevados, e wpor circunferência da cintura elevada, HDL baixa e triacilgliceróis e pressão arterial elevados. A HDL baixa foi o segundo componente mais frequente, mas a maior prevalência de síndrome metabólica (26,8%) foi observada na presença de triglicerídeos elevado. CONCLUSÕES O ERICA é o primeiro estudo nacional a apresentar prevalências de síndrome metabólica e descrever a participação dos seus componentes. Apesar de a prevalência da síndrome metabólica ter sido baixa, as altas prevalências de alguns componentes e de participação de outros na composição da síndrome torna importante o diagnóstico precoce de tais alterações, mesmo que não agrupadas na síndrome metabólica.

ABSTRACT OBJECTIVE To determine the prevalence of metabolic syndrome and its components in Brazilian adolescents. METHODS We evaluated 37,504 adolescents who were participants in the Study of Cardiovascular Risks in Adolescents (ERICA), a cross-sectional, school-based, national study. The adolescents, aged from 12 to 17 years, lived in cities with populations greater than 100,000 inhabitants. The sample was stratified and clustered into schools and classes. The criteria set out by the International Diabetes Federation were used to define metabolic syndrome. Prevalences of metabolic syndrome were estimated according to sex, age group, school type and nutritional status. RESULTS Of the 37,504 adolescents who were evaluated: 50.2% were female; 54.3% were aged from 15 to 17 years, and 73.3% were from public schools. The prevalence of metabolic syndrome was 2.6% (95%CI 2.3-2.9), slightly higher in males and in those aged from 15 to 17 years in most macro-regions. The prevalence was the highest in residents from the South macro-region, in the younger female adolescents and in the older male adolescents. The prevalence was higher in public schools (2.8% [95%CI 2.4-3.2]), when compared with private schools (1.9% [95%CI 1.4-2.4]) and higher in obese adolescents when compared with nonobese ones. The most common combinations of components, referring to 3/4 of combinations, were: enlarged waist circumference (WC), low HDL-cholesterol (HDL-c) and high blood pressure; followed by enlarged WC, low HDL-c and high triglycerides; and enlarged WC, low HDL-c, high triglycerides and blood pressure. Low HDL was the second most frequent component, but the highest prevalence of metabolic syndrome (26.8%) was observed in the presence of high triglycerides. CONCLUSIONS ERICA is the first Brazilian nation-wide study to present the prevalence of metabolic syndrome and describe the role of its components. Despite the prevalence of Metabolic Syndrome being low, the high prevalences of some components and participation of others in the syndrome composition shows the importance of early diagnosis of this changes, even if not grouped within the metabolic syndrome.

https://doi.org/10.1590/s01518-8787.2016050006701

10.

ERICA: prevalences of hypertension and obesity in Brazilian adolescents
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Bloch, Katia Vergetti Klein, Carlos Henrique Szklo, Moyses Kuschnir, Maria Cristina C Abreu, Gabriela de Azevedo Barufaldi, Laura Augusta Veiga, Gloria Valeria da Schaan, Beatriz Silva, Thiago Luiz Nogueira da Moraes, Ana Julia Pantoja Oliveira, Ana Mayra Andrade de Tavares, Bruno Mendes Magliano, Erika da Silva Oliveira, Cecília Lacroix de Cunha, Cristiane de Freitas Giannini, Denise Tavares Belfort, Dilson Rodrigues Santos, Eduardo Lima Leon, Elisa Brosina de Oliveira, Elizabete Regina Araújo Fujimori, Elizabeth Borges, Ana Luíza Vasconcelos, Francisco de Assis Guedes Azevedo, George Dantas Brunken, Gisela Soares Guimarães, Isabel Cristina Britto Faria Neto, José Rocha Oliveira, Juliana Souza Carvalho, Kenia Mara B. de Gonçalves, Luis Gonzaga de Oliveira Monteiro, Maria Inês Santos, Marize M. Jardim, Paulo César B. Veiga Ferreira, Pedro Antônio Muniz Montenegro Jr., Renan Magalhães Gurgel, Ricardo Queiroz Vianna, Rodrigo Pinheiro Vasconcelos, Sandra Mary Goldberg, Tamara Beres Lederer

Revista de Saúde Pública

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2016, Volume 50 Suppl. 1 elocation 9s

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Estimar as prevalências de hipertensão arterial e obesidade e a fração atribuível populacional de hipertensão arterial devida à obesidade em adolescentes brasileiros. MÉTODOS Foram avaliados dados dos participantes do Estudo de Riscos Cardiovasculares em Adolescentes, estudo seccional l nacional de base escolar. A amostra foi dividida em 32 estratos geográficos e conglomerados de escolas e turmas, com representatividade nacional, macrorregional e de capitais. Obesidade foi classificada pelo índice de massa corporal segundo idade e sexo. Considerou-se hipertensão arterial a média da pressão arterial sistólica ou diastólica maior ou igual ao percentil 95 da curva de referência. Foram estimadas prevalências e intervalos de confiança de 95% (IC95%) de hipertensão arterial e de obesidade, nacionais e nas macrorregiões do País, por sexo e grupo etário, assim como as frações de hipertensão atribuíveis à obesidade na população. RESULTADOS Foram avaliados 73.399 estudantes, 55,4% do sexo feminino, com média de idade 14,7 anos (DP = 1,6). A prevalência de hipertensão arterial foi 9,6% (IC95% 9,0-10,3); sendo as mais baixas observadas nas regiões Norte, 8,4% (IC95% 7,7-9,2) e Nordeste, 8,4% (IC95% 7,6-9,2) e a mais alta na região Sul, 12,5% (IC95% 11,0-14,2). A prevalência de obesidade foi 8,4% (IC95% 7,9-8,9), mais baixa na região Norte e mais alta na Sul. As prevalências de hipertensão arterial e obesidade foram maiores no sexo masculino. Adolescentes com obesidade tiveram prevalência de hipertensão arterial mais elevada, 28,4% (IC95% 25,5-31,2), do que aqueles com sobrepeso, 15,4% (IC95% 13,8-17,0), ou eutróficos, 6,3% (IC95% 5,6-7,0). A fração de hipertensão arterial atribuível à obesidade foi de 17,8%. CONCLUSÕES O ERICA foi o primeiro estudo brasileiro com representatividade nacional a estimar a prevalência de hipertensão arterial aferida em adolescentes. A fração da prevalência de hipertensão arterial atribuível à obesidade mostrou que cerca de 1/5 dos hipertensos poderiam não ser hipertensos se não fossem obesos.

ABSTRACT OBJECTIVE To estimate the prevalence of arterial hypertension and obesity and the population attributable fraction of hypertension that is due to obesity in Brazilian adolescents. METHODS Data from participants in the Brazilian Study of Cardiovascular Risks in Adolescents (ERICA), which was the first national school-based, cross-section study performed in Brazil were evaluated. The sample was divided into 32 geographical strata and clusters from 32 schools and classes, with regional and national representation. Obesity was classified using the body mass index according to age and sex. Arterial hypertension was defined when the average systolic or diastolic blood pressure was greater than or equal to the 95th percentile of the reference curve. Prevalences and 95% confidence intervals (95%CI) of arterial hypertension and obesity, both on a national basis and in the macro-regions of Brazil, were estimated by sex and age group, as were the fractions of hypertension attributable to obesity in the population. RESULTS We evaluated 73,399 students, 55.4% female, with an average age of 14.7 years (SD = 1.6). The prevalence of hypertension was 9.6% (95%CI 9.0-10.3); with the lowest being in the North, 8.4% (95%CI 7.7-9.2) and Northeast regions, 8.4% (95%CI 7.6-9.2), and the highest being in the South, 12.5% (95%CI 11.0-14.2). The prevalence of obesity was 8.4% (95%CI 7.9-8.9), which was lower in the North region and higher in the South region. The prevalences of arterial hypertension and obesity were higher in males. Obese adolescents presented a higher prevalence of hypertension, 28.4% (95%CI 25.5-31.2), than overweight adolescents, 15.4% (95%CI 17.0-13.8), or eutrophic adolescents, 6.3% (95%CI 5.6-7.0). The fraction of hypertension attributable to obesity was 17.8%. CONCLUSIONS ERICA was the first nationally representative Brazilian study providing prevalence estimates of hypertension in adolescents. Regional and sex differences were observed. The study indicates that the control of obesity would lower the prevalence of hypertension among Brazilian adolescents by 1/5.

https://doi.org/10.1590/s01518-8787.2016050006685

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