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Abstract Background The diagnosis of cognitive disorders in Parkinson disease (PD) can be very challenging. Aiming at establishing uniform and reliable diagnostic procedures, the International Parkinson’s Disease and Movement Disorder Society (MDS) commissioned task forces to delineate diagnostic criteria for mild cognitive impairment (MCI) and dementia in PD. Objectives To investigate the applicability of the MDS recommendations for cognitive evaluation in a Brazilian sample of patients with PD with low levels of formal education. Methods A total of 41 patients with PD were subjected to a comprehensive neuropsychological evaluation based on tests proposed by the MDS, which included the Mini-Mental State Examination, the Mattis Dementia Rating Scale (MDRS), the Trail Making Test (TMT) parts A and B, in addition to language and memory skills assessment. Neuropsychiatric and daily functioning features were also evaluated. Spearman correlation analyses were used to evaluate the association between the scores obtained in the cognitive scales and demographic/clinical variables. Results Although none of the participants had a formal diagnosis of dementia, 50% presented some degree of cognitive impairment when considering the results of the MDRS. Of note, a noticeable number of patients was not able to complete the full neuropsychological assessment. The TMT part B was the most difficult task, being completed by only 22 participants (54%). As expected, the greater the educational level, the better the performance on the cognitive tests. Better motor function was also associated with better scores in cognition. Conclusions Adopting strict inclusion/exclusion criteria and a comprehensive clinical evaluation, we found remarkable limitations for the MDS recommendations when individuals with low educational levels are considered. A revision of the current guidelines is necessary considering differences among populations, especially related to formal education.

Resumo Antecedentes O diagnóstico de distúrbios cognitivos na doença de Parkinson (DP) pode ser muito desafiador. Com o objetivo de estabelecer procedimentos diagnósticos uniformes e confiáveis, a Sociedade Internacional da Doença de Parkinson e Distúrbios do Movimento (MDS, na sigla em inglês) encomendou forças-tarefa para delinear critérios diagnósticos para comprometimento cognitivo leve (CCL) e demência na DP. Objetivos Investigar a aplicabilidade das recomendações da MDS para avaliação cognitiva em uma amostra brasileira de pacientes com DP de baixa escolaridade. Métodos Um total de 41 pacientes com DP foram submetidos a uma avaliação neuropsicológica abrangente com base nos testes propostos pela MDS, que incluiu o Miniexame do Estado Mental, a Escala de Avaliação de Demência de Mattis (MDRS, na sigla em inglês), o teste de trilhas (TMT, na sigla em inglês) partes A e B, além da avaliação das habilidades de linguagem e memória. Características neuropsiquiátricas e de funcionamento diário também foram avaliadas. Análises de correlação de Spearman foram utilizadas para avaliar a associação entre os escores obtidos nas escalas cognitivas e variáveis demográficas/clínicas. Resultados Apesar de nenhum dos participantes ter diagnóstico formal de demência, 50% apresentaram algum grau de comprometimento cognitivo ao levar em consideração os resultados da MDRS. Vale ressaltar que um número notável de pacientes não conseguiu completar a avaliação neuropsicológica completa. A parte B do TMT foi a tarefa mais difícil, sendo realizada por apenas 22 participantes (54%). Como esperado, quanto maior o nível educacional, melhor o desempenho nos testes cognitivos. Melhor função motora também foi associada a melhores escores em cognição. Conclusões Adotando critérios rígidos de inclusão/exclusão e uma avaliação clínica abrangente, encontramos limitações marcantes para as recomendações da MDS quando considerados indivíduos com baixa escolaridade. É necessária uma revisão das diretrizes atuais considerando as diferenças entre as populações, principalmente relacionadas ao nível educacional.

https://doi.org/10.1055/s-0042-1759761

The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal
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Lamas, Carlos José Einicker

; Fachin, Diego Aguilar

; Falaschi, Rafaela Lopes

; Alcantara, Daniel Máximo Correa de

; Ale-Rocha, Rosaly

; Amorim, Dalton de Souza

; Araújo, Maíra Xavier

; Ascendino, Sharlene

; Baldassio, Letícia

; Bellodi, Carolina Ferraz

; Bravo, Freddy

; Calhau, Julia

; Capellari, Renato Soares

; Carmo-Neto, Antonio Marcelino do

; Cegolin, Bianca Melo

; Couri, Márcia Souto

; Carvalho, Claudio José Barros de

; Dios, Rodrigo de Vilhena Perez

; Falcon, Aida Vanessa Gomez

; Fusari, Livia Maria

; Garcia, Carolina de Almeida

; Gil-Azevedo, Leonardo Henrique

; Gomes, Marina Morim

; Graciolli, Gustavo

; Gudin, Filipe Macedo

; Henriques, Augusto Loureiro

; Krolow, Tiago Kütter

; Mendes, Luanna Layla

; Limeira-de-Oliveira, Francisco

; Maia, Valéria Cid

; Marinoni, Luciane

; Mello, Ramon Luciano

; Mello-Patiu, Cátia Antunes de

; Morales, Mírian Nunes

; Oliveira, Sarah Siqueira

; Patiu, Claudemir

; Proença, Barbara

; Pujol-Luz, Cristiane Vieira de Assis

; Pujol-Luz, José Roberto

; Rafael, José Albertino

; Riccardi, Paula Raile

; Rodrigues, João Paulo Vinicios

; Roque, Fabio de Oliveira

; Sallum, Maria Anice Mureb

; Santis, Marcelo Domingos de

; Santos, Charles Morphy Dias dos

; Santos, Josenilson Rodrigues dos

; Savaris, Marcoandre

; Shimabukuro, Paloma Helena Fernandes

; Silva, Vera Cristina

; Schelesky-Prado, Daniel de Castro

; Silva-Neto, Alberto Moreira da

; Camargo, Alexssandro

; Sousa, Viviane Rodrigues de

; Urso-Guimarães, Maria Virginia

; Wiedenbrug, Sofia

; Yamaguchi, Carolina

; Nihei, Silvio Shigueo

Revista Brasileira de Entomologia

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2023, Volume 67 N. 4 elocation e20230051

Abstract: En | Text: En | PDF: En

ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists.

https://doi.org/10.1590/1806-9665-rbent-2023-0051

Code infarction initiative of Bajio region, during the pandemic by COVID-19 in a reconversion hospital
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Villar-Valencia, Cristian Adrián

; Hernández-González, Martha Alicia

; Borrayo-Sánchez, Gabriela

; Celis-Quintal, Juan German

; Solorio-Meza, Sergio Eduardo

; Medina-Torres, Oscar Samuel

; Gutiérrez-Galván, Maraí Xochitl

; Rodríguez-Martínez, Braulio

; Prado-Rodríguez, Luis Humberto

; Vázquez-Morones, Ana Laura

; Alatoma-Medina, Juan Pablo

; Hernández-Estala, Jorge

; Patiño-Amaya, Aristóteles

; Magdaleno-Serrano, Hugo Ivan

; Rodríguez-Déniz, Carmen

; Arellano-Sotelo, Hugo

; Nava-Hernández, Guillermo

; Ramírez-Vázquez, Ricardo

; Chimal-Flores, Marco Antonio

; Alegría-Peredia, Emiliano

; Ramos-González, Gerardo Rubén

; Pérez-Benítez, Rigoberto

; Bermúdez-Acévez, Erik

; Valencia-Martínez, Hypatia

; Segovia-Solís, Hugo

; López-Varela, Manuel

; Monroy-Córdoba, Doryan

; Marmolejo-López, Adriana

; Báez-Montes, Alfredo

; Hernández-Cerqueda, Fabián

; Nolasco-Muñoz, Luis Ricardo

; Vargas-Ramírez, Luis Manuel

; Celis-Quintal, Juan German

; Bernal-Ruíz, Enrique Alfredo

; Delgado-Sánchez, Anabella

; Sánchez-López, José Manuel

; Bautista-López, Germán Ramón

; Acevedo-Gómez, Pablo Francisco

; Acuña-Valerio, Jorge Francisco

; González-Ortíz, Oracio

; Hernández-Padilla, Adolfo Asahel

; Solórzano-Vázquez, Marco Alejandro

; Franco-Herrera, Noel

; González, Luis Jonathan

; Reyes-Álvarez, José Miguel

; Salinas-Cavazos, Iván Rosendo

; Tiscareño-Villanueva, Ashby Daniel

; Vidrio-Villaseñor, Ramiro

; Fernández-Yáñez, Gabriel

; Meza, Ma. Guadalupe

; Nucamendi-Solórzano, Freeman Issac

; Sandoval-Uribe, José de Jesús

; Sotelo-García, Luis David

; Zamoaya-Paz, Luis Carlos

; Espriu, Donovan Fernando

; García-Rodríguez, Román

; López-Ibarra, Daniel Eugenio

; López-Valencia, Andrea Janeth

; Villar-Valencia, Cristian Adrián

; Navarro-Pérez-Macedo, Javier

Cardiovascular and metabolic science

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sep 2022, Volume 33 N. 3 Pages 97 - 105

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: Introduction: Acute myocardial infarction has a high prevalence and possibility of death if timely care is not given. It is possible that treatment could be delayed during a health crisis such as the COVID-19 pandemic. Objective: The objective of this study was to evaluate the impact of the COVID-19 pandemic on the function of the infarction code in the High Specialty Medical Unit of our institution. The medical indicators of acute coronary ischemic syndrome with ST-segment elevation were compared at two times: before the COVID-19 pandemic and during it. Material and methods: An ambispective, analytical, comparative cohort study was conducted, comparing the periods of February-September 2019 and February-September 2020, in the High Specialty Medical Unit, Centro Médico del Bajío number 1, Instituto Mexicano del Seguro Social, Leon, Guanajuato, Mexico. All patients older than 18 years with clinical, electrocardiographic, and enzymatic data of acute coronary ischemic syndrome, accepted in the medical network as infarction code registered in the National Registry of Acute Coronary Ischemic Syndromes (RENASCA) electronic case report form were included in the study. Results: The independent samples t-test was used to determine the impact of the infarction code initiative based on the reperfusion therapies performed, the door-to-needle, the door-to-balloon time, and the ischemia time. There was a significant difference in the reperfusion strategy, with greater thrombolysis during the COVID-19 pandemic (57.4% versus 72.6%, odds ratio [OR] 1.97, 95% confidence interval [CI] 0.49-0.82, p < 0.001), as well as reperfusion criteria (21.03% versus 35.37%, OR 2.05, 95% CI 0.53-0.80, p < 0.0001). Mortality was not different between the time periods. Conclusions: The COVID-19 pandemic has not impacted operation of the infarction code in the High Specialty Medical Unit Centro Médico del Bajío number 1 because the medical indicators of acute coronary ischemic syndrome with ST-segment elevation did not change.

resumen está disponible en el texto completo

https://doi.org/10.35366/107622

Lesión renal aguda en COVID-19. Análisis en el Hospital Ángeles Mocel
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Prado Lozano, Pamela Michelle

; Cortés Colula, Fernando

; Delgado Nava, Mariana

; Fernández Macías Valadez, Antonio

; Luna Hernández, Andrea Magdalena

; Mesinas Garrido, Mayte

; Velasco García Lascurain, Francisco

; Villeda Aguilar, María de los Ángeles

; Ovando Morga, Daniel Fernando

Acta médica Grupo Ángeles

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jun 2021, Volume 19 N. 2 Pages 236 - 243

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: Introduction: Acute kidney injury (AKI) is common in COVID-19 patients. Nonetheless, its actual incidence is based in case series and retrospective studies, reporting a wide range of presentations. It has been suggested that AKI is an independent risk factor for mechanical ventilation and death in patients with that viral infection. Material and methods: Observational, descriptive, cross-sectional and retrospective study. The files of interned patients at Hospital Ángeles Mocel between March and July 2020, with a COVID-19 diagnosis, were reviewed. Patients over 18 years old, with a confirmed COVID-19 diagnosis and a complete file were included (n = 83). A descriptive analysis to calculate percentages, means and standard deviation was employed. Results: 36.14% of patients developed AKI, 43.3% were classified as KDIGO 1, 20% as KDIGO 2, 36.6% as KDIGO 3, and 23.3% required kidney replacement therapy. Of the patients under invasive mechanical ventilation, 77.7% developed AKI. Out of the total of patients with AKI, 56.6% died. Conclusions: The incidence of AKI in COVID-19 patients in our population, was similar to that reported in the international literature. AKI was more frequent in patients hospitalized in intensive care units and under invasive mechanical ventilation, in which a higher mortality was observed.

Resumen: Introducción: La lesión renal aguda (LRA) es común en enfermos con COVID-19. Sin embargo, su incidencia actual se basa en series de casos y estudios retrospectivos, que reportan un rango muy amplio de presentación. Se ha sugerido que la LRA es un factor de riesgo independiente para el requerimiento de ventilación mecánica y muerte intrahospitalaria en pacientes con dicha enfermedad viral. Material y métodos: Estudio observacional, descriptivo, transversal y retrospectivo. Se revisaron los expedientes de enfermos internados en el Hospital Ángeles Mocel con diagnóstico de COVID-19, entre marzo y julio del 2020. Se incluyeron personas mayores de edad, con diagnóstico confirmado de esa infección y expediente clínico completo (n = 83). Se utilizó estadística descriptiva a fin de calcular porcentajes, medias y desviación estándar. Resultados: El 36.14% desarrolló LRA, 43.3% fueron nivel uno de KDIGO (Kidney Disease: Improving Global Outcomes), 20% en KDIGO 2, 36.6% KDIGO 3 y 23.3% requirieron terapia de reemplazo de riñón. De quienes tenían ventilación mecánica invasiva (VMI), 77.7% generaron LRA. El 56.6% de aquellos con LRA fallecieron. Conclusiones: La incidencia de LRA en afectados con COVID-19 en esta población fue similar a lo reportado en la literatura internacional. Fue más frecuente en pacientes en unidad de cuidados intensivos y con VMI, en quienes se observó más alta mortalidad.

https://doi.org/10.35366/100448 64 downloads

Preeclampsia: Universal Screening or Universal Prevention for Low andMiddle-Income Settings?
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Rolnik, Daniel Lorber

; Carvalho, Mario Henrique Burlacchini de

; Lobo, Guilherme Antonio Rago

; Verlohren, Stefan

; Poon, Liona

; Baschat, Ahmet

; Hyett, Jon

; Thilaganathan, Basky

; Bujold, Emmanuel

; Costa, Fabricio da Silva

; Oliveira, Leandro De

; Diniz, Angélica Lemos Debs

; Prado, Caio Antônio de Campos

; Da Cunha Filho, Edson Vieira

; Souza, Francisco Lázaro Pereira De

; Korkes, Henri Augusto

; Ramos, José Geraldo

; Costa, Maria Laura

; Corrêa Junior, Mário Dias

; Sass, Nelson

; Cavalli, Ricardo De Carvalho

; Martins-Costa, Sérgio Hofmeister De Almeida

; Peraçoli, José Carlos

Revista Brasileira de Ginecologia e Obstetrícia

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apr 2021, Volume 43 N. 4 Pages 334 - 338

Abstract: En | Text: En | PDF: En

https://doi.org/10.1055/s-0041-1729953 83 downloads

Pre-eclampsia: Universal Screening or Universal Prevention for Low andMiddle-Income Settings?
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Oliveira, Leandro Gustavo De

; Diniz, Angélica Lemos Debs

; Prado, Caio Antônio de Campos

; Cunha Filho, Edson Vieira Da

; Souza, Francisco Lázaro Pereira De

; Korkes, Henri Augusto

; Ramos, José Geraldo

; Costa, Maria Laura

; Corrêa Junior, Mário Dias

; Sass, Nelson

; Cavalli, Ricardo De Carvalho

; Martins-Costa, Sérgio Hofmeister De Almeida

; Peraçoli, José Carlos

Revista Brasileira de Ginecologia e Obstetrícia

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jan 2021, Volume 43 N. 1 Pages 61 - 65

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A Pré-eclâmpsia (PE) é uma doença grave que acomete ~ 8% das gestações e representa importante causa de morbimortalidade, tanto materna quanto perinatal. O rastreamento da doença émotivo de estudos, porém a complexidade e as incertezas quanto a sua etiologia tornam esse objetivo bastante difícil. Além disso, os custos relacionados com o rastreamento, a heterogeneidade das populações mais afetadas e ainda a falta de métodos de prevenção de grande eficácia reduzem o potencial dos algoritmos de rastreamento. Assim, a Comissão Nacional Especializada sobre Hipertensão na Gravidez da Federação Brasileira das Associações de Ginecologia e Obstetrícia (CNE Hipertensão na Gravidez da FEBRASGO) considera que não há algoritmos de rastreamento que possam ser aplicados no país nesse momento e defende a utilização dos métodos de prevenção como ácido acetilsalicílico e cálcio de maneira ampla.

Abstract Pre-eclampsia (PE) is a severe disorder that affects up to 8% of all pregnancies and represents an important cause of maternal and perinatal morbidity and mortality. The screening of the disease is a subject of studies, but the complexity and uncertainties regarding its etiology make this objective a difficult task. In addition, the costs related to screening protocols, the heterogeneity of the most affected populations and the lack of highly effective prevention methods reduce the potential of current available algorithms for screening. Thus, the National Specialized Commission of Hypertension in Pregnancy of the Brazilian Association of Gynecology and Obstetrics Federation (Febrasgo, in the Portuguese acronym) (NSC Hypertension in Pregnancy of the Febrasgo) considers that there are no screening algorithms to be implemented in the country to date and advocates that Aspirin and calcium should be widely used.

https://doi.org/10.1055/s-0040-1713803 1892 downloads

Avaliação Psicológica em Concursos Públicos e Porte de Arma: Histórico e Desafios
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Faiad, Cristiane

; Santos, Andersson Pereira dos

; Lobosque, Elza Maria Gonçalves

; Sant'Anna Filho, Olavo

; Prado, Lyani Vieira do

; Coelho Junior, Francisco Antônio

Psicologia: Ciência e Profissão

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2021, Volume 41 N. spe1 elocation e252456

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Trata-se de um estudo teórico que aborda a avaliação psicológica no contexto de avaliações compulsórias, tanto em concurso público quanto para posse ou porte de arma de fogo. São apresentados os maiores desafios da área, a partir do histórico e da exposição de alguns dos problemas enfrentados na prática, diante das diferentes normativas que regulam este contexto. Na avaliação psicológica em concursos, ressalta-se como um dos maiores desafios a forte influência do poder judiciário nos últimos 60 anos, que inclui a definição ou restrição de procedimentos na atuação do profissional. Quanto à avaliação para porte de arma de fogo, discutem-se as diversas mudanças que ocorreram nos últimos anos e suas implicações. O texto incentiva os profissionais que atuam na área a refletir sobre as consequências sociais que o resultado dessa avaliação pode trazer. No Brasil, as pesquisas realizadas no contexto de avaliação psicológica compulsória ainda são escassas, o que mostra a necessidade de estudos que contribuam para melhoria nesse campo de atuação. É necessário compreender, inclusive, os impactos que a publicação de normativas e a qualidade da atuação dos profissionais podem provocar, bem como seus efeitos sobre a sociedade como um todo.

Abstract This theoretical study addresses psychological assessment in the context of compulsory exams for civil service entrance examination and firearms licenses. By presenting the history and some issues related to regulations, this article presents the greatest challenges in the area of compulsory exams. When it comes to procurement exams, a major challenge accounts for the strong influence of the judiciary over the past 60 years, defining or restricting procedures in professional performance. As for firearms license exams, the article expatiates on several changes that have occurred in recent years, as well as their implications. The text encourages professionals working in the field to reflect upon the social consequences of this assessment results. Studies on compulsory psychological assessment are still scarce in the Brazilian literature, indicating the need for research to improve this field of action. Moreover, one should also consider the impacts of regulations and quality professionals on these assessments and on society as a whole.

Resumen Este estudio teórico aborda la evaluación psicológica en el contexto de las evaluaciones obligatorias tanto en concurso público como por posesión o portación de armas de fuego. Se presentan los mayores desafíos del área a partir de la historia y de algunos de los problemas que se enfrentan en la práctica, dadas las diferentes normativas que regulan este contexto. En el contexto de la evaluación psicológica en los concursos públicos, uno de los mayores desafíos es la fuerte influencia del Poder Judicial en los últimos 60 años, que incluye la definición o restricción de procedimientos en el desempeño del profesional. En cuanto a la evaluación para portación de arma de fuego, se discuten los distintos cambios que se han producido en los últimos años y sus implicaciones. El texto anima a los profesionales que trabajan en el área a reflexionar sobre las consecuencias sociales que puede traer el resultado de esta evaluación. En Brasil, la investigación realizada en el contexto de la evaluación psicológica obligatoria es aún escasa, lo que muestra la necesidad de estudios que contribuyan a la mejora en este campo de acción. Incluso es necesario comprender los impactos que puede causar la publicación de normativas y la calidad del desempeño de los profesionales, así como sus efectos en la sociedad en su conjunto.

https://doi.org/10.1590/1982-3703003252456 509 downloads

Evaluation of the effect of hospitalization on mortality in patients with heart failure followed in primary care
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Prado-Galbarro, Francisco J.

; Gamiño-Arroyo, Ana E.

; Sánchez-Piedra, Carlos

; Sánchez-Pájaro, Andrés

; Sarría-Santamera, Antonio

Archivos de cardiología de México

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jun 2019, Volume 89 N. 2 Pages 130 - 137

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Background: Heart failure (HF) is a serious health-care problem. The aim of this study is to evaluate the effect of the first acute episode of decompensated HF that requires a hospitalization on the survival of newly diagnosed cases of HF with follow-up for 5 years in primary care (PC). Methods: This was a longitudinal observational study of a retrospective cohort of patients with information extracted from electronic medical records of PC. Incident cases of HF from 2006 to 2010 or until death were studied through a survival analysis with Kaplan–Meier and Cox proportional hazards multivariate regression, after applying the propensity score matching technique (PSM). Results: A total of 3061 new cases of HF were identified. The PSM analysis was performed with 529 couples, with a total of 1058 patients. 5-year survival was 65% in no hospitalized and 53% in hospitalized patients. Factors with an increased risk of mortality were having prescribed nitrates (heart rate [HR] = 1.56; 1.08-2.24). Factors with protective effect were having received the annual influenza vaccine (HR = 0.04; 0.01-0.15) and having been indicated X-rays by PC physician (HR = 0.76; 0.67-0.88). Conclusions: The findings indicate that hospitalizations are associated with a significant increase in mortality in patients recently diagnosed with HF. It is important to reinforce the need for the prevention of acute decompensated HF and for strategies to improve post-discharge outcomes.

Resumen Antecedentes: La insuficiencia cardiaca (IC) es un serio problema de asistencia médica. El objetivo de este estudio es evaluar el efecto del primer episodio de IC aguda descompensada que requiere una hospitalización en la supervivencia de los casos de IC recientemente diagnosticados con un seguimiento de 5 años en Atención Primaria (AP). Métodos: Estudio observacional longitudinal de una cohorte retrospectiva de pacientes con información extraída de la historia clínica electrónica de AP. Se estudiaron los casos incidentes de IC desde 2006 a 2010 o hasta su fallecimiento con un análisis de supervivencia de Kaplan-Meier y un modelo de regresión de Cox, después de aplicar la técnica del Propensity Score Matching (PSM). Resultados: Se identificaron 3.061 casos nuevos de IC. El análisis PSM se realizó con 529 pareja, con un total de 1.058 pacientes. La supervivencia a los cinco años fue del 65% en pacientes no hospitalizados y del 53% en pacientes hospitalizados. Los factores con mayor riesgo de mortalidad fueron tener prescritos nitratos (HR = 1,56; 1,08-2,24). Los factores con efecto protector fueron haber recibido la vacuna anual de la gripe (HR = 0,04; 0,01-0,15) y haber sido indicadas radiografías por el médico de AP (HR = 0,76; 0,67-0,88). Conclusiones: Los hallazgos indican que las hospitalizaciones se asocian con un aumento significativo de la mortalidad en pacientes diagnosticados recientemente con IC. Es importante reforzar la necesidad de prevenir la IC descompensada aguda y las estrategias para mejorar los resultados posteriores al alta.

https://doi.org/10.24875/acm.m19000022 146 downloads

10.

Linfangioma quístico retroperitoneal: Un tumor infrecuente en la edad adulta
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de Andrés-Gómez, Alejandra

; Melero Abellán, Antonio

; Ismail, Ali

; Navarro Moratalla, Carla

; Vázquez-Prado, Antonio

; Villalba Ferrer, Francisco

Revista argentina de cirugía

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jun 2018, Volume 110 N. 2 Pages 114 - 116

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Background: lymphangiomas are rare benign tumors of the lymphatic system, being more common in the pediatric population. Intra-abdominal localization is very rare; only 1 % of lymphangiomas appear in the retroperitoneum. We report a case of a rare tumor because of its location and the elderly age of presentation. Retroperitoneal lymphangioma is a rare tumor with an unertain pathogenesis. Diagnosis is usually confirmed by imaging studies , e.g., US, MRI or CT. Although they are benign tumors, complete surgical resection is the treatment of choice. With this treatment, complications like infection, perforation or bleeding are prevented. Our case is unusual because of the retroperitoneal location of the tumor and the late age of presentation.

Los linfangiomas son tumores benignos raros del sistema linfático, más comunes en la población pediátrica. La localización intraabdominal es muy infrecuente: tan solo el 1% de los linfangiomas aparece en el retroperitoneo. Se describe una tumoración quística infrecuente tanto por su localización como por la edad de presentación. Los linfangiomas retroperitoneales son tumores raros y su etiopatogenia es incierta. El diagnóstico se realiza mediante estudios de imagen; las técnicas de elección son la ultrasonografía (USG), la resonancia magnética (RM) o la tomografía computarizada (TC). A pesar de que se trata de tumores de naturaleza benigna, la exéresis quirúrgica completa es el tratamiento de elección para prevenir complicaciones como la sobreinfección, la rotura o el sangrado. Nuestro caso resulta infrecuente tanto por la localización retroperitoneal del tumor como por la tardía edad de presentación.

373 downloads

11.

Bayesian model and spatial analysis of oral and oropharynx cancer mortality in Minas Gerais, Brazil
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Fonseca, Emílio Prado da

; Oliveira, Cláudia Di Lorenzo

; Chiaravalloti Neto, Francisco

; Pereira, Antonio Carlos

; Vedovello, Silvia Amélia Scudeler

; Meneghim, Marcelo de Castro

Ciência & Saúde Coletiva

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jan 2018, Volume 23 N. 1 Pages 153 - 160

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste estudo foi determinar a taxa de mortalidade por câncer de boca e aplicar o Modelo Bayesiano Empírico e a Análise Espacial para suavizar a taxa bruta de mortalidade por câncer de boca e orofaringe. Foi usado o Capítulo II da Classificação Internacional de Doenças (CID-10) para Categorias C00 a C14. Os dados foram extraídos do Sistema de Informações sobre Mortalidade do Brasil (SIM) do Estado de Minas Gerais. As estatísticas descritivas e as taxas brutas de mortalidade foram calculadas para cada município. Posteriormente, foram aplicados os estimadores Bayesianos Empíricos. Em 2012, em Minas Gerais, foram registradas 769 mortes para o câncer de boca e orofaringe, dos quais 607 (78,96%) eram homens e 162 (21,04%) mulheres. Houve uma grande variação na distribuição espacial da taxa de mortalidade bruta. Foi possível identificar aglomeração nas regiões Sul, Central e Norte com maior precisão pelo Estimador Bayesiano Modelo Global e Local. Através dos Modelos Bayesian foi possível mapear aglomeração espacial de mortes por câncer de boca e orofaringe com maior precisão. Assim, pela epidemiologia espacial foi possível obter resultados mais precisos e fornecer subsídios para ações para reduzir a mortalidade por este tipo de câncer.

Abstract The objective of this study was to determine of oral and oropharynx cancer mortality rate and the results were analyzed by applying the Spatial Analysis of Empirical Bayesian Model. To this end, we used the information contained in the International Classification of Diseases (ICD-10), Chapter II, Category C00 to C14 and Brazilian Mortality Information System (SIM) of Minas Gerais State. Descriptive statistics were observed and the gross rate of mortality was calculated for each municipality. Then Empirical Bayesian estimators were applied. The results showed that, in 2012, in the state of Minas Gerais, were registered 769 deaths of patients with cancer of oral and oropharynx, with 607 (78.96%) men and 162 (21.04%) women. There was a wide variation in spatial distribution of crude mortality rate and were identified agglomeration in the South, Central and North more accurately by Bayesian Estimator Global and Local Model. Through Bayesian models was possible to map the spatial clustering of deaths from oral cancer more accurately, and with the application of the method of spatial epidemiology, it was possible to obtain more accurate results and provide subsidies to reduce the number of deaths from this type of cancer.

https://doi.org/10.1590/1413-81232018231.17022015 126 downloads

12.

Bayesian model and spatial analysis of oral and oropharynx cancer mortality in Minas Gerais, Brazil
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Fonseca, Emílio Prado da

; Oliveira, Cláudia Di Lorenzo

; Chiaravalloti Neto, Francisco

; Pereira, Antonio Carlos

; Vedovello, Silvia Amélia Scudeler

; Meneghim, Marcelo de Castro

Ciência & Saúde Coletiva

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jan 2018, Volume 23 N. 1 Pages 153 - 160

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232018231.17022015 1849 downloads

13.

Morbidity in extreme low birth weight newborns hospitalized in a high risk public maternity
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Sousa, Derijulie Siqueira

; Sousa Júnior, Airton Salviano

; Santos, Arielly Duarte Rabelo

; Melo, Enaldo Vieira

; Lima, Sônia Oliveira

; Almeida-Santos, Marcos Antônio

; Reis, Francisco Prado

Revista Brasileira de Saúde Materno Infantil

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mar 2017, Volume 17 N. 1 Pages 139 - 147

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivos: determinar a prevalência das morbidades mais comuns em recém-nascidos de extremo baixo peso (RNEBP) internados em uma unidade de terapia intensiva neonatal (UTIN) e avaliar a influência dessas morbidades no tempo de internamento. Métodos: estudo observacional, longitudinal, prospectivo e analítico, na UTIN de uma maternidade publica referência em alto risco do estado de Sergipe, realizado com 158 RNEBP admitidos no período de março de 2014 a abril de 2015. A análise do tempo de internamento foi realizada através do método Kaplan- Meier. Resultados: os RNEBP apresentaram médio de 785,2g ± 138,2g. A idade gestacional variou entre 22 e 35 semanas e média de 26,8 semanas. Dos admitidos na UTIN, 63 (39,9%) receberam alta e 95 (60,1%) tiveram óbito como desfecho. O tempo de internamento foi influenciado por morbidades como: persistência do canal arterial (PCA), hemorragia intracraniana e sepse. Síndrome do desconforto respiratório foi a morbidade mais comum 157 (99,4%). A incidência de persistência do canal arterial, hemorragia intraventricular, sepse, hipotermia , hipoglicemia e retinopatia da prematuridade foi de 39,2%, 17,1%, 32,3%,50,3%, 52,3% e 16,6%respectivamente. Conclusões: as morbidades do aparelho respiratório, cardíacas, neurológicas e infecciosas foram as mais prevalentes, enquanto a PCA, hemorragia intracraniana e sepse foram as morbidades que influenciaram significativamente o tempo de internação.

Abstract Objectives: to determine the prevalence of the most common morbidities in extremely low birth weight (ELBW) infants hospitalized in a newborn intensive care unit (NICU) and to evaluate the influence of these morbidities through the length of in-hospital stay. Methods: observational, longitudinal, prospective and analytical study in a high risk reference maternity NICU from Sergipe, realized with 158 ELBW infants admitted between March 2014 and April 2015. The analysis of the hospitalization time was realized through the Kaplan-Meier method. Results: the average weight of premature was 785,2g ± 138,2g. The gestational age vary from 22 to 35 weeks and the average was 26,8 weeks. Of those admitted at NICU, sixty three (39,9%) were discharged and 95 (60,1%) died. The time of hospitalization was influenced for morbidities as: patent ductus arteriosus (PDA), intraventricular hemorrhage and sepsis. Acute respiratory distress syndrome was the most common complication (157 - 99,4%). The incidence of persistent arterial duct, intraventricular hemorrhage, sepsis, hypothermia, hypoglycemia and retinopathy of prematurity was 39,2%, 17,1%, 32,3%,50,3%, 52,3% e 16,6% respectively. Conclusions: the morbidities from respiratory tract, cardiac, neurological and infectious were the most prevalent, whilst PDA, intraventricular hemorrhage and sepsis were the morbidities that significantly influenced the time of hospitalization.

https://doi.org/10.1590/1806-93042017000100008 11345 downloads

14.

Comparación de métodos para modelizar los factores asociados con los ingresos hospitalarios en casos incidentes de insuficiencia cardíaca
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Prado-Galbarro, Francisco Javier

; del-Cura-González, Isabel

; Garrido-Elustondo, Sofía

; Gamiño-Arroyo, Ana Estela

; Sánchez-Piedra, Carlos

; Sarría-Santamera, Antonio

Revista Española de Salud Pública

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2017, Volume 91 elocation e201705034

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Background: Heart failure (HF) is an important public health problem due to its increasing prevalence, and the decompensation associated with hospital admission represents an increased risk of death. The objective of this study was to compare several methods to model the variable hospitalizations and to determine the effect of factors associated with hospital admissions in incident cases of HF. Methods: Study of a retrospective cohort of patients with information extracted from electronic medical records of PC was performed. Patients 24 year and older with at least 1 visit to PC in 2006 were included. Registered hospital admissions of HF incident cases between 2006 and 2010 or until death were analyzed and comparison of Poisson, Negative Binomial (NB), zero-inflated and Hurdle regression models were conducted to identify factors associated con hospitalizations. Results: 3,061 patients were identified in a cohort of 227,984. Regarding the factors associated with hospitalizations and according to the zero inflated NB regression model, patients who presented valvular disease (OR=2.01; CI95% 1.22-3.30), or were being treated with antithrombotics (OR=3.45; CI95%: 1.61-7.42) or diuretics (OR=2.28; CI95% 1.13-4.58) had a lower likelihood of hospitalization. Factors associated with a higher rate of hospital admissions were having valvular disease (IRR=1.37; CI95% 1.03-1.81) or diabetes mellitus (IRR=1.38; 1.07-1.78), and being treated with calcium antagonists (IRR=1.35; CI95% 1.05- 1.73) or ACE inhibitors (IRR=1.43; CI95% 1.06- 1.92). Having being referred to a cardiologist had a protective effect (IRR=0.86; CI95% 0.76- 0.97). Conclusion: The regression model that obtained the best adjustment was the zero inflated NB. According to this model, the factors associated with an increase in hospital admissions were valvulopathies, diabetes and treatment with calcium antagonists.

RESUMEN Fundamento: La insuficiencia cardiaca (IC) es un importante problema de salud pública debido a su creciente prevalencia y la descompensación que conlleva un ingreso hospitalario representa un aumento del riesgo de muerte. El objetivo de este trabajo fue comparar varios métodos para modelizar la variable hospitalizaciones y determinar el efecto de los factores asociados con los ingresos hospitalarios en casos incidentes de IC. Método: Se realizó un estudio de cohortes restrospectivo con información extraída de la historia clínica electrónica de Atención Primaria (AP). Se incluyeron pacientes mayores de 24 años que habían realizado al menos 1 consulta en AP durante el año 2006. Se analizaron las hospitalizaciones registradas de casos incidentes de IC entre 2006 y 2010 o hasta su fallecimiento y se compararon modelos de regresión de Poisson, Binomial Negativa (BN), inflados con ceros y de Hurdle para identificar factores asociados a las hospitalizaciones. Resultados: Se identificó a 3.061 personas con IC en una cohorte de 227.984 pacientes. Respecto a los factores asociados con las hospitalizaciones y según el modelo de regresión BN inflado con ceros, los pacientes con valvulopatías (OR=2,01; IC95%: 1,22-3,30) o en tratamiento con antitrombóticos (OR=3,45; IC95%: 1,61-7,42) o diuréticos (OR=2,28; IC95%:1,13-4,58) tuvieron mayor probabilidad de hospitalización. Los factores asociados a una mayor tasa de ingresos fueron tener valvulopatías (IRR=1,37; IC95%: 1,03-1,81) o diabetes mellitus (IRR=1,38, 1,07-1,78) y estar en tratamiento con calcioantagonistas (IRR=1,35; IC95%: 1,05-1,73) o IECAS (IRR=1,43; IC95%:1,06-1,92). Haber tenido derivaciones a cardiología tuvo efecto protector (IRR=0,86; IC95%: 0,76-0,97). Conclusión: El modelo de regresión que tiene mejor ajuste es el BN inflado con ceros. Según este modelo los factores asociados con un incremento en los ingresos hospitalarios son las valvulopatías, la diabetes mellitus y el tratamiento con calcioantagonistas.

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15.

Comparación de métodos para modelizar los factores asociados con los ingresos hospitalarios en casos incidentes de insuficiencia cardíaca
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Prado-Galbarro, Francisco Javier

; del-Cura-González, Isabel

; Garrido-Elustondo, Sofía

; Gamiño-Arroyo, Ana Estela

; Sánchez-Piedra, Carlos

; Sarría-Santamera, Antonio

Revista Española de Salud Pública

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2017, Volume 91 elocation e201705034

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

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