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Asociación entre dependencia funcional y calidad de vida en pacientes adultos mayores oncológicos
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Cardenas, Graciela

; Flores-Lovon, Kevin

; Perez-Acuña, Katherine

; Gutiérrez, Ericson L.

; Runzer-Colmenares, Fernando M.

; Parodi, José F.

Revista Cubana de Medicina Militar

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jun 2022, Volume 51 N. 2 elocation e1796

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: The presence of comorbidities modulates the aging process, the diagnosis of cancer can significantly compromise the health of the elderly, which affects their quality of life. Objective: Determine the association between the functional dependence and the quality of life in elderly oncology patients treated with radiotherapy. Methods: Retrospective analytical study, carried out in 181 outpatients of Centro Médico Naval del Callao, Perú, male, older than 60 years. The functional dependence was assessed with Barthel index and Lawton scale; and the quality of life was assessed with World Health Organization Quality of Life-Older Adults Module (WHOQoL-Old). Results: A statistically significant association was found between functional dependence and quality of life, for both the basic activities of daily living (PR= 1.04 [IC 95 %: 1.01-1.07]), and the instrumental activities of daily living (PR= 1.08 [IC 95 %: 1.01 - 1.13]). Conclusion: There was significant association between the functional dependence and the poor quality of life in the elderly oncology patients treated with radiotherapy.

RESUMEN Introducción: La presencia de comorbilidades modula el proceso de envejecimiento, el diagnóstico de cáncer puede comprometer de manera importante la salud del adulto mayor, lo cual repercute en su calidad de vida. Objetivo: Determinar la asociación entre la dependencia funcional y la calidad de vida en pacientes oncológicos adultos mayores tratados con radioterapia. Métodos: Estudio analítico retrospectivo, realizado en 181 pacientes ambulatorios del Centro Médico Naval del Callao, Perú, varones, mayores de 60 años. Se valoró la dependencia funcional mediante los índices de Barthel y el de Lawton; y la calidad de vida mediante la escala de calidad de vida en adultos mayores de la Organización Mundial de la Salud (WHOQoL-Old). Resultados: Se encontró asociación estadísticamente significativa entre dependencia funcional y calidad de vida, tanto para las actividades básicas de la vida diaria (PR= 1,04 [IC 95 %; 1,01-1,07]) como para las actividades instrumentales de la vida diaria (PR= 1,08 (IC 95 %: 1,01 - 1,13). Conclusiones: En los pacientes adultos mayores oncológicos tratados con radioterapia, se encuentra asociación significativa entre dependencia funcional y una pobre calidad de vida.

Implementation of two robotic flagmen controlled by CAN messages to increase the safety of human workers in road maintenance
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Lopez-Flores, David

; Ramirez-Alonso, Graciela

; Aguirre-Prieto, Daniel

; Acosta-Corral, Martin

; Armendariz-Camargo, Arturo

; Granados-Perez, Brian

Journal of applied research and technology

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2020, Volume 18 N. 4 Pages 169 - 177

Abstract: En | Text: En | PDF: En

Abstract: Commonly, the improper signaling in road construction zones is the cause of different accidents to drivers, pedestrians, and road construction workers. The signaling used when a vehicle is approaching a repairing section could be classified into two classes: stationary or active. Nevertheless, active warning systems have demonstrated to reduce accidents in road work zones. Within the active signaling class we have: portable changeable message sign, flashing arrow signs, flagman, to mention some. This paper describes the implementation of two robotic flagmen controlled by the Controller Area Network (CAN) protocol. Each robotic flagman can perform four different actions: speed reduction (right and left) and lane change (right and left). The electronic circuitry and mechanical motors of the two robotic flagmen have the option to be powered by a solar charging system considering working zones where there is no access to the electric grid. The solar charging system guarantees a sufficient electrical power supply for night conditions operations. Also, the CAN protocol can be used to monitor the correct operability of the robotic flagmen thus eliminating the need to incorporate more expensive electronic devices such as cameras. The hardware combination in the control, monitoring, and solar charging system allow us to propose a low-cost practical implementation. The results of our implementation show that the longest response time of the robot is less than 850 ms once that the CAN message has been sent to the network. This demonstrates that our proposal can meet real-time implementation requirements.

https://doi.org/10.22201/icat.24486736e.2020.18.4.1191 69 downloads

Numerical and experimental comparative of coupled neighboring buildings
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Peña, Luis Alejandro Perez

; Doz, Graciela Nora

; Avila, Suzana Moreira

Revista IBRACON de Estruturas e Materiais

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2020, Volume 13 N. 6 elocation e13609

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

resumo: Nos últimos anos têm sido implementada uma técnica de controle de vibrações chamada de acoplamento estrutural. Essa técnica consiste em ligar duas edificações vizinhas por meio de um dispositivo de acoplamento, com o objetivo de diminuir os efeitos dinâmicos em função das propriedades mecânicas de cada estrutura. Ao fazê-lo, em princípio, é possível controlar a resposta de ambas as estruturas simultaneamente, o que é precisamente a atratividade da técnica. Dado o seu potencial, este trabalho tem como objetivo avaliar numérica e experimentalmente a eficácia dela utilizando pórticos planos simples quando submetidos a um movimento oscilatório na base provocado por uma mesa vibratória, projetada e construída no Laboratório de Estruturas da Universidade de Brasília. Inicialmente, foram calculadas as respostas dinâmicas numéricas dos modelos com e sem acoplamento. Em seguida, experimentalmente, os pórticos planos foram fixados na mesa vibratória e foram submetidos a um movimento na base quando desacoplados e acoplados a fim de obter os registros de acelerações e assim obter seus espectros de frequência. Finalmente, foram comparados os espectros obtidos experimentalmente com os obtidos numericamente. Os resultados apresentados mostraram a eficiência do método de controle por meio do acoplamento, a qual foi afetada principalmente pelas propriedades mecânicas dos edifícios adjacentes e dos elementos de conexão.

abstract: In recent years a vibration control technique, called structural coupling, has been studied. This technique consists on linking two neighboring buildings, through a coupling device, with the purpose of reducing dynamic response. It is possible to control both structures response simultaneously, which is precisely the attractiveness of this technique. Given the potential of the structural coupling technique, this work evaluates numerically and experimentally the performance of the structural coupling technique in simple plane frames when subjected to an oscillatory movement in at base caused by a shaking table, designed and built in the Structure Laboratory of University of Brasilia. Initially, the model numerical dynamic responses, without and with coupling, were obtained. Then, experimentally, the plane frames were fixed to the shaking table and subjected to a base movement uncoupled and coupled in order to obtain the acceleration registers and its frequency spectra. Finally, numerical and experimental frequency spectra were compared. The results obtained showed the efficiency of the control method through coupling, which depends mainly on the mechanical properties of adjacent buildings and connecting devices.

https://doi.org/10.1590/s1983-41952020000600009 409 downloads

Revisores 2020
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Alonso, Daniela

; Alvarez, José Manuel

; Arrivillaga, Christiane

; Guerrero, María Elena Ávila

; Barreto, Ana Claudia

; Bertolotto, Fernando

; Brunet, Nicolás

; Bruno, Gabriela

; Brussino, Silvina

; Castillo, Mauricio

; Chiarino, Nicolás

; Correa-Moreira, Gonzalo

; Daguerre, Leticia

; Dias, Hélia

; Díaz, Alvaro

; Díaz, Daniela

; Duero, Dante

; Elices, Matilde

; FreibergHoffmann, Agustín

; Frías, Pamela

; Garcés, Magadalena

; Rubiano, Mónica García

; Guidotti, Carolina

; Hernandez, José Augusto

; Huerta, Fernando

; Labarthe, Javier

; Leopold, Sandra

; López-Steinmetz, Cecilia

; Mailhos, Alvaro

; Mercado Maya, Aida

; Michelini, Yanina

; Mola, Débora

; Quintana, Adriana Molas de la

; Montero, Federico

; Berges, Beatriz Montes

; Orejuela, Johnny

; Palermo Moreira, Cássia Regina

; Pechorro, Pedro

; Pereira, José Carlos

; Acosta, Andrés Perez

; Plachot, Graciela

; Quintana, Alberto Manuel

; Melognio, Alejandro Raggio

; Ramos, Valeria

; Leite, Umbelina Rego

; Estrada, Erika Robles

; Ayan, Maria Noel Rodriguez

; Santos, Paul Ruiz

; Spinatelli, Jorge Salvo

; Schenck, Marcela

; Sánchez, Hugo Selma

; Simkin, Hugo

; Soldatova, Elena

; Abella, Alicia María Sosa

; Tosi, Jeremías David

; Tutte, Verónica

; Ungaretti, Joaquín

; Bálsamo, Pilar Uriarte

; Vales, Lisandro

; Garay, Rosa Maria Varela

Psicología, Conocimiento y Sociedad

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2020, Volume 10 N. 3 Pages 173 - 174

Abstract: Es | Text: Es | PDF: Es

https://doi.org/10.26864/pcs.v10.n3.rev

Reacciones adversas a medicamentos antirretrovirales en pacientes con virus de la inmunodeficiencia humana
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Mendo Alcolea, Neity

; Mesa Perez, Eduardo de Jesús

; Neyra Barrios, Rafael

; Berenguer Gournaluses, Lázaro

; Nieto Muñiz, Graciela

MEDISAN

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oct 2018, Volume 22 N. 8 Pages 674 - 682

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT A descriptive and cross sectional study of 40 patients with HIV belonging to the Teaching Polyclinic "Frank País García" in Santiago de Cuba was carried out with the aim of identifying the adverse reactions to antirretroviral drugs during the first semester of 2018. Most of the notifications were carried out by specialists in Comprehensive General Medicine (61,4%) in the case material, followed by those of Internal Medicine and Licentiate in Nursing (8,8 and 17,6%, respectively); also, among the predominant adverse effects there were nauseas, migraine and sickness, fundamentally with the therapeutic schemes constituted by lamivudina-zidovudina-nevirapina and zidovudina-nevirapina-efavirenz. It is concluded that during antirretroviral treatment most of these reactions were classified as definitive, independently of the prescribed therapeutic scheme and the concomitant diseases.

RESUMEN Se efectuó un estudio descriptivo y transversal de 40 pacientes con VIH pertenecientes al Policlínico Docente “Frank País García” de Santiago de Cuba, con vistas a identificar las reacciones adversas a medicamentos antirretrovirales durante el primer semestre de 2018. En la casuística, la mayoría de las notificaciones las realizaron los especialistas en Medicina General Integral (61,4 %), seguidos por los de Medicina Interna y los licenciados en Enfermería (8,8 y 17,6 %, respectivamente); asimismo, entre los efectos adversos predominantes figuraron las náuseas, la cefalea y los mareos, fundamentalmente con los esquemas terapéuticos constituidos por lamivudina-zidovudina-nevirapina y zidovudina-nevirapina-efavirenz. Se concluye que durante el tratamiento antirretroviral la mayoría de dichas reacciones fueron clasificadas como definitivas, independientemente del esquema terapéutico prescrito y las enfermedades concomitantes.

IFN-γR2 is strongly expressed on endothelial cells of gingival tissues from patients with chronic periodontitis
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Franco-Topete, Ramón

; Zepeda-Nuño, José Sergio

; Zamora-Perez, Ana Lourdes

; Fuentes-Lerma, Martha Graciela

; Gómez-Meda, Belinda Claudia

; Guerrero-Velázquez, Celia

Journal of Applied Oral Science

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2018, Volume 26 elocation e20170291

Abstract: En | Text: En | PDF: En

Abstract Chronic periodontitis (CP) is characterized by gingival inflammation and bone destruction. It has been reported that interferon-gamma (IFN-γ) levels are high in CP patients; however, the IFN-γ receptor (IFN-γR) has not been studied in gingival tissue from these patients. Objective: To evaluate IFN-γ levels and IFN-γR expression in gingival tissue biopsies from chronic periodontitis patients compared with healthy subjects (HS). Material and Methods: Gingival tissues were obtained from all study subjects, CP (n = 18) and healthy subjects (HS) (n = 12). A tissue section of each study subject was embedded in paraffin blocks to determine the expression of IFN-γ R (IFN-γR1 and IFN-γR2) through immunohistochemistry. Another section of the tissue was homogenized and IFN-γ was measured by the ELISA technique. Results: No significant differences were found in the IFN-γR1 expression within the cell layers of the gingival tissue of the study groups. When analyzing the IFN-γR2 expression it was found that IFN-γR2 is strongly expressed in the endothelial cells of CP patients when compared to HS (p<0.05). IFN-γ concentrations in the gingival tissue were significantly higher in CP patients than in HS. No significant correlation between IFN-γ levels and the expression of IFN-γR1 and IFN-γR2 was found. However, a positive correlation between IFN-γ levels and clinical parameters [probing depth (PD) and clinical attachment level (CAL)] was found. Conclusion: The study of IFN-γR expression in gingival tissue samples from patients with CP showed an increase only in the IFN-γR2 chain in endothelial cells when compared to HS.

https://doi.org/10.1590/1678-7757-2017-0291 730 downloads

Guías de práctica clínica en el Perú: evaluación de su calidad usando el instrumento AGREE II
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Canelo-Aybar, Carlos

; Balbin, Graciela

; Perez-Gomez, Ángela

; Florez, Iván D.

Revista Peruana de Medicina Experimental y Salud Pública

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dec 2016, Volume 33 N. 4 Pages 732 - 738

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT To evaluate the methodological quality of clinical practice guidelines (CPGs) put into practice by the Peruvian Ministry of Health (MINSA), 17 CPGs from the ministry, published between 2009 and 2014, were independently evaluated by three methodologic experts using the AGREE II instrument. The score of AGREE II domains was low and very low in all CPGs: scope and purpose (medium, 44%), clarity of presentation (medium, 47%), participation of decision-makers (medium, 8%), methodological rigor (medium, 5%), applicability (medium, 5%), and editorial independence (medium, 8%). In conclusion, the methodological quality of CPGs implemented by the MINSA is low. Consequently, its use could not be recommended. The implementation of the methodology for the development of CPGs described in the recentlypublished CPG methodological preparation manual in Peru is a pressing need.

RESUMEN Con el fin de evaluar la calidad metodológica de las guías de práctica clínica (GPC) desarrolladas por el Ministerio de Salud (MINSA) de Perú, se evaluaron 17 GPC del MINSA publicadas entre 2009-2014, por tres expertos metodológicos, de forma independiente, usando el instrumento AGREE II. La puntuación de los dominios del AGREE II fue baja y muy baja en todas las GPC: alcance y propósito (mediana, 44%), claridad de la presentación (mediana, 47%), participación de decisores (mediana, 8%), rigor metodológico (mediana 5%), aplicabilidad (mediana, 5%), e independencia editorial (mediana, 8%). Se concluye que la calidad metodológica de las GPC del MINSA es baja. Como consecuencia, no es posible recomendar su uso. Urge la incorporación de metodología estandarizada para el desarrollo de GPC de calidad en el Perú.

https://doi.org/10.17843/rpmesp.2016.334.2559 367 downloads

Guías de práctica clínica en el Perú: evaluación de su calidad usando el instrumento AGREE II
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Canelo-Aybar, Carlos

; Balbin, Graciela

; Perez-Gomez, Ángela

; Florez, Iván D

Revista Peruana de Medicina Experimental y Salud Publica

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oct 2016, Volume 33 N. 4 Pages 732 - 738

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

To evaluate the methodological quality of clinical practice guidelines (CPGs) put into practice by the Peruvian Ministry of Health (MINSA), 17 CPGs from the ministry, published between 2009 and 2014, were independently evaluated by three methodologic experts using the AGREE II instrument. The score of AGREE II domains was low and very low in all CPGs: scope and purpose (medium, 44%), clarity of presentation (medium, 47%), participation of decision-makers (medium, 8%), methodological rigor (medium, 5%), applicability (medium, 5%), and editorial independence (medium, 8%). In conclusion, the methodological quality of CPGs implemented by the MINSA is low. Consequently, its use could not be recommended. The implementation of the methodology for the development of CPGs described in the recently-published CPG methodological preparation manual in Peru is a pressing need.

Con el fin de evaluar la calidad metodológica de las guías de práctica clínica (GPC) desarrolladas por el Ministerio de Salud (MINSA) de Perú, se evaluaron 17 GPC del MINSA publicadas entre 2009-2014, por tres expertos metodológicos, de forma independiente, usando el instrumento AGREE II. La puntuación de los dominios del AGREE II fue baja y muy baja en todas las GPC: alcance y propósito (mediana, 44%), claridad de la presentación (mediana, 47%), participación de decisores (mediana, 8%), rigor metodológico (mediana 5%), aplicabilidad (mediana, 5%), e independencia editorial (mediana, 8%). Se concluye que la calidad metodológica de las GPC del MINSA es baja. Como consecuencia, no es posible recomendar su uso. Urge la incorporación de metodología estandarizada para el desarrollo de GPC de calidad en el Perú.

https://doi.org/10.17843/rpmesp.2016.334.2559

Cystic Fibrosis Cloud database: Un sistema informático para el almacenamiento y manejo de datos clínicos y microbiológicos del paciente con fibrosis quística
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Prieto, Claudia I

; Palau, María J

; Martina, Pablo

; Achiary, Carlos

; Achiary, Andrés

; Bettiol, Marisa

; Montanaro, Patricia

; Cazzola, María L

; Leguizamón, Mariana

; Massillo, Cintia

; Figoli, Cecilia

; Valeiras, Brenda

; Perez, Silvia

; Rentería, Fernando

; Diez, Graciela

; Yantorno, Osvaldo M

; Bosch, Alejandra

Revista argentina de microbiología

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mar 2016, Volume 48 N. 1 Pages 27 - 37

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.ram.2015.11.002 264 downloads

10.

Extensão universitária e prática dos agentes comunitários de saúde: acolhimento e aprendizado cidadão
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Silva, Carlos Roberto de Castro e

; Chiaperini, Pâmela Talamoni

; Frutuoso, Maria Fernanda Petroli

; Morell, Maria Graciela Gonzalez Perez de

Saúde e Sociedade

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jun 2014, Volume 23 N. 2 Pages 677 - 688

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A intervenção interdisciplinar universitária em regiões de alta vulnerabilidade da Baixada Santista, além de contribuir para o fortalecimento do Sistema Único de Saúde (SUS), evidencia o sofrimento enfrentado pelo agente comunitário de saúde (ACS) em seu dia a dia, advindo de solicitações dos munícipes. Estas resultantes da exclusão e violência social em que vivem acrescidas de condições de trabalho insalubres e baixa remuneração. O objetivo deste artigo é apresentar a sistematização de uma experiência de intervenção por meio de um projeto de extensão universitária, trazendo elementos que potencializem as ações dos agentes comunitários de saúde da Estratégia Saúde da Família (ESF) na Baixada Santista. Para este estudo qualitativo, foram analisados os diários de campo dos encontros semanais, a partir da percepção de professores e alunos, referentes ao período de agosto de 2010 a junho de 2011. A organização e análise dos dados tiveram como referência a Teoria Fundamentada nos dados. Os resultados indicaram a necessidade de acolhimento de experiências dos ACSs, ampliando a compreensão dos dilemas vividos por estes profissionais e consequentemente dos impasses de implementação do SUS e da ESF. Além disso, o incentivo ao processo de educação continuada baseada em uma práxis que promova os projetos de vida pessoais e profissionais dos ACSs.

The interdisciplinary intervention by the university in areas of high vulnerability of Santos, besides contributing to the strengthening of the Brazilian National Health System (SUS), highlights the suffering faced by community health agents (CHA) in their routines, coming from requests from citizens. These result from social exclusion and the violence in which they live, as well as unhealthy working conditions and low pay. The purpose of this article is to present an experience of systematic intervention through a university extension project, bringing elements that enhance the actions of community health agents of the Family Health Strategy (FHS) in Santos. For this qualitative study we analyzed the field diaries of weekly meetings, from the perspective of teachers and students, for the period from August 2010 to June 2011. Data’s organization and analysis were based on the Grounded Theory. The results indicated the need of gathering the CHA experiences, broadening the understanding of the dilemmas faced by these professionals and consequently the impasses of implementing SUS and the FHS. Moreover, continued education should be encouraged, based upon a praxis able to promote CHA’s personal and professional projects.

https://doi.org/10.1590/S0104-12902014000200026 3803 downloads

11.

Extensão universitária e prática dos agentes comunitários de saúde: acolhimento e aprendizado cidadão
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Silva, Carlos Roberto de Castro e

; Chiaperini, Pâmela Talamoni

; Frutuoso, Maria Fernanda Petroli

; Morell, Maria Graciela Gonzalez Perez de

Saúde e Sociedade

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jun 2014, Volume 23 N. 2 Pages 677 - 688

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/S0104-12902014000200026 130 downloads

12.

Inter-annual reproductive trait variation and spawning habitat preferences of Engraulis ringens off northern Chile
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Claramunt, Gabriel

; Castro, Leonardo R

; Cubillos, Luis A

; Hirche, Hans-Jürgen

; Perez, Graciela

; Braun, Mauricio

Revista de biología marina y oceanografía

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aug 2012, Volume 47 N. 2 Pages 227 - 243

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Along the Humboldt Current System, the anchoveta (Engraulis ringens) is distributed between 4ºS and 42ºS. Environmental conditions differ markedly both between spawning areas and seasonally. Hence, different reproductive tactics are expected in response to the environment. Here we used information from Daily Egg Production Method surveys to study latitudinal and interannual variability of the reproductive parameters in stocks of E. ringens from the northern (18° 20' to 26° 00'S) and southern (33° 00 to 41° 30'S) Chilean coast. The main goal was to investigate potential preferences for temperature and chlorophyll concentration in the spawning habitat and changes in the reproductive potential and egg size of anchoveta in response to the prevalent habitat conditions, mainly temperature. Temperature was not a relevant environmental variable to determine geographical position of the spawning areas in E. ringens. High chlorophyll-a concentration appears as the selected variable for spawning habitat. According to our results, the interannual changes in the body weight-fecundity relationship are related to the temperature of the environment, which affects the egg size. We postulate, therefore, that instead of searching for certain temperatures, anchoveta accommodate their offspring characteristics according to the prevalent environment (e.g., egg size, fecundity). The response of the reproductive system to temperature might be in the scale of spawning frequency, i.e., weeks.

A lo largo del Sistema de la Corriente de Humboldt, la anchoveta (Engraulis ringens) se distribuye entre los 4°S y 42°S. Las condiciones ambientales difieren notablemente tanto entre las zonas de desove y las estaciones del año. Por lo tanto, diferentes tácticas reproductivas se esperan en respuesta al medio ambiente. En este estudio se utilizó la información proveniente de cruceros para la aplicación del Método de Producción Diaria de Huevos (MPDH) para estudiar la variabilidad latitudinal e interanual de los parámetros reproductivos de las poblaciones de E. ringens en la zona norte (18° 20' a 26°00'S) y sur (33° 00' a 41° 30'S) de Chile. El objetivo principal es investigar las potenciales preferencias por ciertos rangos de temperatura y concentración de clorofila-a en el hábitat de desove y los cambios en el potencial reproductivo y tamaño de los huevos de anchoveta en respuesta a las condiciones del hábitat, en especial a la temperatura. Los resultados muestran que la temperatura no es una variable relevante del medio ambiente para determinar la posición geográfica de las zonas de desove de E. ringens. Altas concentraciones de clorofila sería la variable seleccionada para los cambios en la posición de las áreas de desove. Se postula que en lugar de preferir cierto rango de temperatura, anchoveta acomoda los productos del desove de acuerdo a las condiciones predominantes del medio ambiente (ej. tamaño del huevo, fecundidad) y esta respuesta sería en la escala de la frecuencia de desove, es decir, semanas.

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13.

Fiebre "Q" en Uruguay
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Moreira, R. E. Somma

; Caffarena, R. M.

; Perez, Graciela

; Saldas, Silvana Somma

; Monteiro, Marina

Revista do Instituto de Medicina Tropical de São Paulo

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jun 1987, Volume 29 N. 3 Pages 168 - 173

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

The authors review the conditions concerning "Q" fever, both from the clinical and epidemiological point of view. The first national case was communicated in 1956, the affected subject being an adult worker from a meat processing plant. In 1966 the first case on a child was described. From then on, several serological surveys v/are carried out on human beings and on animals. Concerning human beings positive results ranked from 4.2% to 5.5%, depending on the year the study was made. In animals, the values rank from 0.9% (local consumption animals) to 30% (industrial type animals) as far as bovines are concerned. As for ovines, in the single study performed, a 10.3% rate of positive findings was reached. In horses, the positive finding rate ranked from 5.5% to 21.7%. A positive rate of 21.2% was the result of the first survey in swines. A more recent one showed 0.0%. Neither fowls nor guinea pigs showed positive sera. Between 1975 and 1985, 14 meat plant outbreaks were studied and the results showed that, of a total a 1358 human cases studied, 60% of them were positive. The patient's most common symptomatology and the nature of the task performed are also listed. Both for the serological studies and for the diagnosis of the clinical cases, the authors use the complement fixation, the capillar agglutination and the layer microagglutination. This last technique was previously described by the authors 21.

Los autores hacen una revisión de la problemática referida a la fiebre Q, tanto desde el punto de vista clínico como epidemiológico. El primer caso nacional se comunicó en el año 1956, en un adulto, obrero de frigorífico. En 1966 se comunica el primer caso en un niño. A partir de esa fecha se realizan varias encuestas serológicas en humanos y en animales. En seres humanos los hallazgos varían entre 4.2% y 5.5% según el año estudiado. En animales se hallaron valores que oscilaron entre 0.9% (animal para abasto) y 30% (animal tipo industria) para bovinos. En ovinos, en el único estudio se halló un 10.3% de positivos. En equinos los valores de positividad variaron de 5.5% a 21.7%. En suinos se refiere un porcentaje de positividad del 21.2% en la primera encuesta, sendo en la más reciente del 0.0%. En aves y cobayos no se evidenciaron sueros positivos. Entre 1975 y 1985 los autores estudiaron 14 brotes en seres humanos en esta-blecimentos de procesamiento de carne, con un total de 1358 casos estudiados, habiéndose confirmado el 60% de ellos. Pasan revista a la sintomatologia común, así como el tipo de tarea de los pacientes. Para los estudios serológicos, como los diagnósticos de los casos clínicos, los autores utilizaron la fijación del complemento, la aglutinación capilar y la microa-glutinación en lámina.

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