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Abstract Background: Real-world, primary data on the treatment of psoriasis are scarce, especially concerning the role of soluble biomarkers as outcome predictors. Objective: The authors evaluated the utility of Th1/Th17 serum cytokines along with clinical characteristics as predictors of drug survival in the treatment of psoriasis. Methods: The authors consecutively included participants with moderate to severe psoriasis who were followed up for 6 years. Baseline interferon-α, tumor necrosis factor-α, and inter-leukin (IL)-2, IL-4, IL-6, IL-10, and IL-17A were measured using a cytometric bead array; clinical data were assessed. The authors calculated hazard ratios (HRs) for drug survival using a Cox proportional hazards model. Results: The authors included 262 patients, most of whom used systemic immunosuppressants or biologics. In the multivariate model, poor quality of life measured by the Dermatology Life Quality Index (HR = 1.04; 95% CI 1.01–1.07; p = 0.012) and elevated baseline IL-6 (HR = 1.99; 95% CI 1.29–3.08; p = 0.002) were associated with treatment interruption. Study limitations: The main limitation of any cohort study is the presence of confounders that could not be detected in clinical evaluation. Conclusions: Poor quality of life and elevated baseline serum IL-6 level predicted treatment interruption in patients with moderate to severe psoriasis. Although IL-6 is not the most important mediator of the inflammatory pathway in the skin environment, it is an interesting biomarker candidate for predicting psoriasis treatment response.

https://doi.org/10.1016/j.abd.2023.03.002

Spatial analysis of hospital-related mortality due to COVID-19 among children and adolescents in Brazil
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Costa, Silmery da Silva Brito

; Branco, Maria dos Remédios Freitas Carvalho

; Pereira, Andressa Rocha

; Costa, Elisa Miranda

; Araújo, Mayra Sharlenne Moraes

; Oliveira, Daniel Cavalcante de

; Oliveira, Bruno Luciano Carneiro Alves de

; Rangel, Maurício Eduardo Salgado

; Tonello, Aline Sampieri

; Lopes, Denise Ailine Monteiro

; Pinheiro, Vanessa Vieira

; Câmara, Ana Patricia Barros

; Santos, Alcione Miranda dos

; Vasconcelos, Vitor Vieira

Ciência & Saúde Coletiva

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2024, Volume 29 N. 1 elocation e19892022

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivou-se realizar uma análise espacial da taxa de mortalidade hospitalar (TMH) por síndrome respiratória aguda grave (SRAG) atribuída à COVID-19 em crianças e adolescentes no Brasil no período de 2020 a 2021. Utilizou-se o método de cluster para agrupar as unidades federativas (UFs) com base na TMH. Em 2020, clusters com altas TMHs foram formados por UFs Norte/Nordeste. Em 2021, houve redução na TMH. Os clusters com maiores taxas permaneceram na região N/NE. Diferenças regionais foram observadas nas TMHs. Os achados podem refletir as desigualdades sociais e o acesso à atenção hospitalar, principalmente na faixa etária de menores de 1 ano pela gravidade da doença neste grupo.

Abstract The objective was to perform a spatial analysis of the hospital mortality rate (HMR) due to severe acute respiratory syndrome (SARS) attributed to COVID-19 among children and adolescents in Brazil from 2020 to 2021. A cluster method was used to group federal units (FUs) based on HMR. In 2020, clusters with high HMRs were formed by north/northeast FUs. In 2021, there was a reduction in HMR. Clusters with higher rates remained in the N/NE region. Regional differences were observed in the HMR. The findings may reflect social inequalities and access to hospital care, especially in the under 1-year-old age group due to the severity of the disease in this group.

https://doi.org/10.1590/1413-81232024291.19892022

Spatial analysis of hospital-related mortality due to COVID-19 among children and adolescents in Brazil
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Costa, Silmery da Silva Brito

; Branco, Maria dos Remédios Freitas Carvalho

; Pereira, Andressa Rocha

; Costa, Elisa Miranda

; Araújo, Mayra Sharlenne Moraes

; Oliveira, Daniel Cavalcante de

; Oliveira, Bruno Luciano Carneiro Alves de

; Rangel, Maurício Eduardo Salgado

; Tonello, Aline Sampieri

; Lopes, Denise Ailine Monteiro

; Pinheiro, Vanessa Vieira

; Câmara, Ana Patricia Barros

; Santos, Alcione Miranda dos

; Vasconcelos, Vitor Vieira

Ciência & Saúde Coletiva

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2024, Volume 29 N. 1 elocation e19892022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.19892022

Spatial analysis of hospital-related mortality due to COVID-19 among children and adolescents in Brazil
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Costa, Silmery da Silva Brito

; Branco, Maria dos Remédios Freitas Carvalho

; Pereira, Andressa Rocha

; Costa, Elisa Miranda

; Araújo, Mayra Sharlenne Moraes

; Oliveira, Daniel Cavalcante de

; Oliveira, Bruno Luciano Carneiro Alves de

; Rangel, Maurício Eduardo Salgado

; Tonello, Aline Sampieri

; Lopes, Denise Ailine Monteiro

; Pinheiro, Vanessa Vieira

; Câmara, Ana Patricia Barros

; Santos, Alcione Miranda dos

; Vasconcelos, Vitor Vieira

Ciência & Saúde Coletiva

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2024, Volume 29 N. 1 elocation e19892022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.19892022

Occurrence of avian reovirus and picobirnavirus in wild birds from an environmental protection area in the Brazilian Amazon
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PEREIRA, Diego

; SOUTO, Lizandra Caroline dos Santos

; GUERRA, Sylvia de Fátima dos Santos

; PENHA-JÚNIOR, Edvaldo Tavares da

; LOBO, Patrícia dos Santos

; SOARES, Luana da Silva

; PINHEIRO, Helder Henrique Costa

; CHAGAS, Elaine Hellen Nunes

; GUIMARÃES, Ricardo José de Paula Souza e

; RAMOS, Bruna Alves

; CHAGAS, Liliane Leal das

; FREITAS, Maria Nazaré Oliveira

; FURTADO, Erilene Cristina da Silva

; RODRIGUES, Jéssica Cecília Pinheiro

; CASSEB, Alexandre do Rosário

; MARTINS, Lívia Caricio

; MASCARENHAS, Joana D’Arc Pereira

Acta Amazonica

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2024, Volume 54 N. 1 elocation e54hs23012

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Wild birds have great prominence in the transmission of diseases to humans, mainly due to their ease of access to human populations, raising concerns about the potential impact of that proximity on public health. The present study reports ARV and PBV occurrence in wild birds from an environmental protection area in the Amazon biome, in Pará state, Brazil. We obtained 155 fecal specimens from 47 species of wild birds for RNA extraction, ARV and PBV detection utilizing molecular methods, nucleotide sequencing, and phylogenetic analysis. ARV prevalence was 0.6% (1/155), being positive in an individual of Myrmotherula longipennis, and PBV prevalence was 1.29% (2/155), affecting two individuals of Guira guira. The PBV strains were assigned to genogroup I based on phylogenetic analysis, and they shared a strong phylogenetic link with strains isolated from different geographic locations. The ARV strain was more closely related to strains that had previously circulated in the same region. The presence of ARV and PBV in this habitat suggests that infection cycles of these agents occur naturally in the wild ecosystem, potentially triggering transmission events between bird species and humans. This is the first study on ARV detection in wild birds in Brazil and the first report on the occurrence of PBV in wild Guira guira. Additional studies are required to determine the epidemiology, origin, evolution, and emergence of new potentially pathogenic viruses in the Amazon.

RESUMO As aves silvestres têm grande destaque na transmissão de doenças ao homem, principalmente pela facilidade de acesso à população humana, levantando preocupações sobre o potencial impacto dessa proximidade no contexto da saúde pública. O presente estudo relata a ocorrência de ARV e PBV em aves silvestres de uma área de proteção ambiental no bioma Amazônico. Obtivemos 155 espécimes fecais de 47 espécies de aves silvestres, que foram submetidos a extração de RNA, detecção de ARV e PBV por técnicas moleculares, sequenciamento nucleotídico e análise filogenética. A prevalência de infecção por ARV foi 0,6% (1/155), sendo positivo em um indivíduo de Myrmotherula longipennis, e a prevalência de PBV foi 1,29% (2/155), afetando dois insdivíduos de Guira guira. A análise filogenética agrupou as cepas de PBV no genogrupo I, mostrando intensa relação filogenética com cepas isoladas de outras regiões geográficas. A cepa de ARV esteve mais relacionada filogeneticamente a cepas previamente circulantes na mesma região. Este é o primeiro estudo sobre detecção de ARV em aves silvestres no Brasil e o primeiro relato sobre a ocorrência de PBV em Guira guira. A circulação de ARV e PBV nesse ambiente demonstra que os ciclos desses agentes estão ocorrendo de forma natural no ecossistema silvestre, o que pode desencadear possíveis eventos de transmissão entre as espécies aviárias e humanos. Estudos adicionais são necessários para determinar a epidemiologia, origem, evolução e surgimento de novos vírus potencialmente patogênicos na Amazônia.

https://doi.org/10.1590/1809-4392202300120

Evaluation of Different Heating Systems for the Hydrolysis of Residual Frying Oil Catalyzed by Free and Immobilized Lipase
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Correia, Thais Bazilli de Almeida

; Sousa, Grazielle Pereira Reis de

; Reis, Willian de Souza Matias

; Theodoro, Janaina Martins

; Hidalgo, Vitor Bertolassi

; Santos, Jorge Henrique Vieira

; Rós, Patrícia Caroline Molgero Da

; Pereira, Ernandes Benedito

Brazilian Archives of Biology and Technology

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2024, Volume 67 elocation e24220625

Abstract: En | Text: En | PDF: En

Abstract Large quantities of residual cooking oil are being increasingly generated in various sectors, as it is often improperly disposed of and causes serious environmental problems. A commonly used alternative is the use of lipases in enzymatic hydrolysis, since it is rather attractive to several sectors, in addition to allowing the use of products generated thereof, such as: free fatty acids, diacylglycerols, monoacylglycerols and free glycerol, moreover, it is capable of operating in mild temperature and pressure conditions. Therefore, the present study aimed to evaluate alternatives for the hydrolysis of residual frying oil by evaluating the efficiency of different types of supports and heating systems using free and immobilized forms of lipase from Burkholderia cepacia (BCL) and Porcine pancreas (PPL) as biocatalyst. Polyhydroxybutyrate (PHB), niobium oxide (Nb2O5) and chitosan (CHIT) were evaluated as support for immobilizing BCL and PPL lipases, and superior results were found regarding the hydrolytic activity of immobilization derivatives using PHB and Nb2O5. Among the heating systems under evaluation, the highest percentage of residual oil hydrolysis was found using the ultrasound system for both free and immobilized lipases, reaching 57.91% hydrolysis for lipases immobilized on Nb2O5 and 61.11% hydrolysis for the derivative immobilized on PHB. The operational stability of both biocatalysts was evaluated using similar half-life time values for both. Thus, it was observed that the ultrasound system was efficient in improving lipase performance in the hydrolysis of free fatty acids, once this unconventional heating system is quite promising for accelerating such enzymatic reactions.

https://doi.org/10.1590/1678-4324-2024220625

Spatial analysis of hospital-related mortality due to COVID-19 among children and adolescents in Brazil
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Costa, Silmery da Silva Brito

; Branco, Maria dos Remédios Freitas Carvalho

; Pereira, Andressa Rocha

; Costa, Elisa Miranda

; Araújo, Mayra Sharlenne Moraes

; Oliveira, Daniel Cavalcante de

; Oliveira, Bruno Luciano Carneiro Alves de

; Rangel, Maurício Eduardo Salgado

; Tonello, Aline Sampieri

; Lopes, Denise Ailine Monteiro

; Pinheiro, Vanessa Vieira

; Câmara, Ana Patricia Barros

; Santos, Alcione Miranda dos

; Vasconcelos, Vitor Vieira

Ciência & Saúde Coletiva

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2024, Volume 29 N. 1 elocation e19892022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232024291.19892022

Fatores associados à internação de usuários encaminhados pela atenção primária para acompanhamento em Centros de Atenção Psicossociais do município de São Paulo, Brasil
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Sanine, Patricia Rodrigues

; Godoi, Lídia Pereira da Silva

; Rosa, Tereza Etsuko da Costa

; Garcia, Érica Marvila

; Belotti, Lorrayne

; Campos, Rosana Teresa Onocko

; Tanaka, Oswaldo Yoshimi

Ciência & Saúde Coletiva

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2024, Volume 29 N. 2 elocation e19932022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study evaluated factors associated with hospitalization related to the mental health of people undergoing follow-up in Psychosocial Care Centers (CAPS, in Portuguese) in the city of São Paulo, Brazil, referred from Primary Health Care (PHC). This was an evaluative study conducted with 297 individuals in 24 adult CAPS. This study analyzed the prevalence ratios (PR) and their respective 95% confidence intervals (95% CI), obtained through Poisson Regression with robust variance. A statistically significant association was found with hospitalization during follow-ups in CAPS: having health insurance and/or medical plan; waiting time between the diagnosis and the first consultation with a non-medical professional of more than seven days; not having received medical advice regarding how long to use medication; not having received a psychopharmaceutical prescription at PHC; and having a medical history of the hospitalization due to mental health. The results warn of the need to expand access to the more socially vulnerable population, in addition to a restructuring of the services in order to provide more interactive and inclusive practices geared toward the singularities of the users.

Resumo Avaliaram-se os fatores associados à internação relacionadas à saúde mental de pessoas em acompanhamento nos Centros de Atenção Psicossocial (CAPS) do município de São Paulo, encaminhadas pela atenção primária (APS). Pesquisa avaliativa com 297 pessoas em 24 CAPS Adulto. Analisaram-se as razões de prevalência (RP) e seus respectivos intervalos de confiança de 95% (IC), obtidas por meio da regressão de Poisson com variância robusta. Mostraram associação estatisticamente significativa com a internação durante o acompanhamento no CAPS: ter plano de saúde/convênio médico; tempo de espera entre diagnóstico e primeiro atendimento com profissional não médico maior que sete dias; não ter sido orientado sobre o tempo de uso da medicação; não receber prescrição de psicofármaco na APS; e ter histórico de ocorrência de internação por saúde mental. Os resultados alertam para a necessidade de ampliação do acesso à população com maior vulnerabilidade social, além de uma reestruturação dos serviços para a oferta de prática mais articuladas e inclusivas, voltadas às singularidades dos usuários.

https://doi.org/10.1590/1413-81232024292.19932022

Dental caries in the permanent dentition and health-related quality of life among children and adolescents with sickle cell disease
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Mendes, Vera Lúcia Duarte da Costa

; Risso, Patrícia A.

; Santos, Marcia Pereira Alves dos

Ciência & Saúde Coletiva

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2024, Volume 29 N. 3 elocation e06752023

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The aim was to associate living, health and oral health conditions with the quality of life (QL) of children and adolescents (CA) with sickle cell disease (SCD). Of the 120 eligible users of a public hematological service, 106 CA with SCD from 6 to 18 years of age, and their caregivers, answered semi-structured questions about socio-demographic, health and oral health conditions. For QL, we used the validated instrument PedsQLSCD™. The oral clinical examination occurred according to the guidelines of WHO and SB Brazil 2010. The majority of CA were non-white people (88%), mean age of 10.4 (±2.9) years, family income of up to two monthly minimum wages, for 03 to 05 members, with diagnosis of sickle cell anemia by neonatal screening, hospitalizations were due allergic crises, polypharmacy and dental caries (51%) were present. “About the Impact of My Pain” was the best-fit model for the QLSCD (adjusted R²=56%; AIC=28.67; p=0.04). Dental caries in permanent dentition worsened the QLSCD (OR=0.53; IC95%=0.35-0.78; p<0.05) and was associated with the type of school, car ownership, number of family members, of complications and of the medications. To overcome this scenario, programmatic actions are required, and implementation of public policies specifically directed towards these groups.

Resumo Objetivou-se associar condições de vida, de saúde e de saúde bucal à qualidade de vida (QLV) de crianças e adolescentes (CA) com Doença Falciforme (DF). Dos 120 usuários elegíveis de um serviço público hematológico, 106 CA entre 6 e 18 anos de idade, e seus cuidadores, responderam questões semiestruturadas sobre condições sociodemográficas, de saúde e saúde bucal. Para a QLV, o instrumento validado PedsQL DF® foi aplicado. Na sequência, realizou-se o exame clínico bucal nas CA segundo diretrizes da OMS e do SB Brasil 2010. A maioria das CA era negra (88%), idade média de 10,4 (±2.9) anos, renda familiar de até dois salários mínimos, para 03 a 05 membros, diagnosticadas na triagem neonatal com anemia falciforme, internadas por crises álgicas, em uso de polifarmácia e com cárie dental (51%). O domínio “Sobre o Impacto da Minha Dor” foi preditivo da QLVDF (R² ajustado =56%; AIC=28.67; p=0,04). Nele, a cárie dental na dentição permanente piorou a QLVDF das CA (OR=0.53; IC95%=0.35-0.78; p<0,05), associando-se ao tipo de escola, posse de carro e do número de membros na família, de complicações da DF e de medicamentos. Os achados ratificam a dor como marca da DF e mostram a importância da saúde bucal na QLDF das CA. A implementação de políticas públicas específicas pode superar esse cenário.

https://doi.org/10.1590/1413-81232024293.06752023

10.

Nutritional value of babassu cake as a substitute for sugarcane in feeding heifers
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Castro, Kélvia Jácome De

; Borges, Iran

; Miotto, Fabrícia Rocha Chaves

; Pimentel, Patrícia Guimarães

; Gomes, Silas Primola

; Moreira, Guilherme Rocha

; Pinto, Andrea Pereira

; Neiva, Jose Neuman Miranda

Revista Ciência Agronômica

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2024, Volume 55 elocation e20207736

Abstract: En | Text: En | PDF: En

ABSTRACT The aim of this study was to evaluate intake, digestibility and performance in dairy heifers fed diets containing increasing levels of babassu cake (0, 100, 200 and 300 g kg-1 dry matter - DM) as a substitute for sugarcane treated with calcium oxide. Twenty-four heifers with an initial mean weight of 190.8 + 40.8 kg were used, distributed in a completely randomised design. The dry matter intake (DMI), neutral detergent fibre intake (NDFI) and acid detergent fibre intake (ADFI), as %BW and g BW-0.75 , showed an increasing linear response. The organic matter intake (OMI) showed a linear increase of 40 g day-1, 0.017%BW and 0.66 g BW-0.75 for each 10 g kg-1 increase in babassu cake in the diet. The apparent digestibility of the dry matter (ADDM) and organic matter (ADOM) showed a quadratic response (P < 0.05), with a minimum of 493 g kg-1 DM for 150 g kg-1 DM and 526.5 g kg-1 DM for 320 g kg-1 DM as a substitute for the sugarcane, respectively. The final mean weight was not altered, presenting a value of 299.7 + 45.5 kg. Daily weight gain (DWG) showed a quadratic response, with the highest value at a substitution level of 190 g kg-1 DM. The feed conversion rate of the DM was not affected by the addition of babassu cake, with an average of 4.6 + 0.74 kg DM kg-1 in weight gain. Babassu cake can substitute hydrolysed sugarcane in heifer diets up to 300 g kg-1 DM, with the greatest weight gain seen at a substitution level of 190 g kg-1 DM.

https://doi.org/10.5935/1806-6690.20240006

11.

Pronaf e desenvolvimento rural: uma análise para minas gerais nos anos de 2006 e 2017
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Silveira, Marina Porto Coelho

; Montenegro, Rosa Livia Gonçalves

; Pereira, Patrícia Alves Rosado

Revista de Economia e Sociologia Rural

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2024, Volume 62 N. 2 elocation e264581

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The main objective of this paper was investigate the possible conditions and the influence of the National Program for Strengthening Family Agriculture (PRONAF) on the rural development of microregions in the state of Minas Gerais, in the years 2006 and 2017. To this end, it was built through from factor analysis, the rural development index (IDR) for the purpose of synthesizing information related to rural development in Minas Gerais. The index was used to analyze possible spatial configurations and rural development conditions according to PRONAF. The main results obtained indicated that, despite the observance of improvements in family establishments, mainly, in economic terms (modernization and income) and the advance of the IDR of some microregions, the state of Minas Gerais was unable to boost its rural development only with the PRONAF. Although the distribution of the Program's resources in poorer regions was significant in 2006, in the year 2017, there was a directing of resources to regions with greater potential and whose agricultural production is turned to the foreign market.

Resumo O objetivo principal do artigo foi investigar as possíveis condições e a influência do Programa Nacional de Fortalecimento da Agricultura Familiar (PRONAF) sobre o desenvolvimento rural de microrregiões de Minas Gerais, nos anos de 2006 e 2017. Para tanto, foi construído o índice de desenvolvimento rural (IDR), por intermédio da análise fatorial. Em seguida, o IDR foi utilizado para analisar as possíveis condições do desenvolvimento rural de acordo com o PRONAF, a partir da análise qualitativa comparativa (QCA). Os principais resultados obtidos indicam que, apesar da observância de melhorias nos estabelecimentos familiares, principalmente em termos econômicos e o avanço do IDR em algumas microrregiões, Minas Gerais não conseguiu impulsionar o seu desenvolvimento rural somente com o PRONAF. Embora a distribuição dos recursos do programa em regiões mais carentes tenha sido significativa em 2006, no ano de 2017 observou-se o direcionamento dos recursos para regiões de maior potencial e produção agrícola voltada para o mercado externo.

https://doi.org/10.1590/1806-9479.2023.264581

12.

Leprosy in children under fifteen years of age in the most hyperendemic municipality in Brazil
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Costa, Ricardo Milhomem

; Menezes, Marcela Silva

; Guimarães, Maria Sortênia Alves

; Franchi, Eliane Patrícia Pereira

; Monteiro, Lorena Dias

; Alvim, Mariana Caroline Tocantins

Revista Paulista de Pediatria

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2024, Volume 42 elocation e2023022

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To describe leprosy involvement and physical disability profiles in children and adolescents under 15 years old. Methods: Ecological time series study, based on data from the Brazilian Notifiable Diseases Information System, including new cases of leprosy residing in Palmas (TO), from 2001 to 2020. Results: A total of 471 notified cases in children and adolescents under 15 years of age were evaluated, resulting in a detection coefficient of 26.5 per 100,000 inhabitants. Of these, 52% (n=243) were women, 5% (n=24) corresponded to grade two disability, and 36% (n=168) were diagnosed through spontaneous demand. The temporal trend analysis showed a 0.5% reduction in the detection coefficient. There was a significant decrease in the diagnosis of the undetermined and tuberculoid clinical forms and a significant increase in the dimorphous form. Diagnosis through contact examination increased significantly by 13.1% and that through spontaneous demand decreased by 4.9%. The detection coefficient of cases with grade two disability reduced significantly by 7.4% while those with grade one increased by 16.8%. Conclusions: Despite the downward trend in the detection coefficient in children and adolescents under 15 years of age and in cases with grade two disability, other factors indicate failure in the adequate management of leprosy in Palmas.

RESUMO Objetivo: Descrever os perfis de acometimento de hanseníase e incapacidade física em menores de 15 anos. Métodos: Estudo ecológico de série temporal, baseado em dados do Sistema Nacional de Agravos de Notificação, incluindo casos novos de hanseníase residentes em Palmas (TO), no período de 2001 a 2020. Resultados: Foram avaliados 471 casos notificados em crianças e adolescentes menores de 15 anos, resultando em um coeficiente de detecção de 26,5 por cem mil habitantes. Destes, 52% (n=243) eram do gênero feminino, 5% (n=24) correspondiam ao grau dois de incapacidade física, e 36% (n=168) foram diagnosticados por demanda espontânea. A análise de tendência temporal mostrou queda do coeficiente de detecção em 0,5%. Houve queda significativa no diagnóstico das formas clínicas indeterminada e tuberculoide e aumento significativo da dimorfa. O diagnóstico por exame de contato teve um aumento significativo de 13,1% e o por demanda espontânea, queda significativa de 4,9%. O coeficiente de detecção de casos com grau dois de incapacidade apresentou uma queda significativa de 7,4%, enquanto o de casos com grau um, apresentou um aumento de 16,8%. Conclusões: Apesar da tendência de queda do coeficiente de detecção em menores de 15 anos e do coeficiente de detecção de casos com grau dois de incapacidade, outros fatores indicam falha no manejo adequado da hanseníase em Palmas.

https://doi.org/10.1590/1984-0462/2024/42/2023022

13.

Análise Social: seis décadas de temas e problemas
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Dantas, Allysson

; Pereira, Cícero Roberto

; Aboim, Sofia

; Silva, Filipe Carreira da

; Pereira, Victor

; Matos, Patrícia Ferraz de

Análise Social

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dec 2023, N. 249 Pages 672 - 686

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Este artigo analisa estatisticamente os títulos dos artigos publicados na Análise Social (1963-2022), comparando as palavras utilizadas ao longo de seis décadas. Parte-se da premissa de que a escolha de determinadas palavras é reveladora de diversos “mundos do texto”, organizados em função de motivações e interesses distintos. Enunciadas em determinados contextos históricos e mediadas pelo trabalho das sucessivas equipas editoriais, as palavras constituintes dos léxicos da revista mostram linhas de continuidade e mudança temática ao longo do tempo.

Abstract This article analyses, from a statistical point of view, the titles of the articles published in Análise Social (from 1963 to 2022), by comparing the words used over these six decades. Starting from the premise that a certain choice of words reflect a diverse set of “textual worlds”, which are organised according to different motivations and interests, these words, produced under certain historical contexts and mediated by the work of the journal’s editorial teams reveal both the continuity and the thematic changes that shaped its lexicon over time.

https://doi.org/10.31447/as00032573.2023249.02

14.

SARS-CoV-2 Antibody Response to Vaccination in Peritoneal Dialysis Patients
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Donato*, Beatriz

; Mateus*, Catarina

; Roxo, Maria Inês

; Duarte, Carlos Pereira

; Calça, Rita Ribeiro

; Matias, Patrícia João

; Branco, Patrícia

Portuguese Journal of Nephrology & Hypertension

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dec 2023, Volume 37 N. 4 Pages 192 - 195

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Chronic kidney disease patients have a higher risk of infection and worse clinical outcomes after coronavirus disease. We aimed to assess the prevalence of infection and the humoral response after vaccination in peritoneal dialysis patients. Methods: Three types of vaccines were administered (two doses) with the antibody detection at least six months after. Coronavirus disease 2019 infections, hospital admissions, and deaths were evaluated. Results: From 70 prevalent patients, 45 were included. There was a significant increase in antibody level, with a median of 92 (36, 447) U/mL. Only 4% of patients remained seronegative. History of immunosuppressive therapy was associated with no response (100% vs 60%, p=0.010). There were two infections after the vaccination, without hospital admission. Conclusion: Immunization against coronavirus disease was effective in generating a humoral response in peritoneal dialysis patients. There was also an evident impact of immunosuppressive therapy on vaccine response in peritoneal dialysis patients.

https://doi.org/10.32932/pjnh.2023.11.262

15.

Core curriculum in cariology for dentistry degrees in the Republic of Argentina
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Carletto-Kórber, Fabiana PM

; Sorazabal, Ana

; Medici, Silvia

; Ali, Sofía

; Barrionuevo, Alejandra

; Cardozo, Juana

; Cucchi, Analía

; D'Eramo, Luciana

; Escandriolo, Jorge

; Fontanetti, Pablo

; García, Shirley

; Lombardo, Adriana

; Mardenlli, Alejandra

; Masoli, Carla

; Mulbany, Patricia

; Pereira, Lía

; Pérez, Silvia

; Preliasco, Mariana

; Rossi, Glenda

; Squassi, Aldo

; Ulloque, Jorgelina

; Vaculik, Patricia

; Ventrera, Verónica

; Bordoni, Noemí

; Giacaman, Rodrigo A

Acta Odontológica Latinoamericana

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dec 2023, Volume 36 N. 3 Pages 183 - 190

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Aim To prepare a consensus document of the cariology contents and competences included in the curriculum for the dentistry degree at Argentine dental faculties/schools Materials and Method Planning the process in stages: Stage 1- Diagnosis of the situation (Google Form) and invitation to participate extended to the 20 academic units (AU) that offer dentistry degrees. Stage 2- Assessment process of Content (C) and Competences (I) agreements in the five domains: D1 Basic Sciences, D2 Risk and diagnosis of dental caries, D3 Decision-making for non-invasive treatments, D4 Decision-making for invasive treatment, and D5 Evidence-based cariology at community level. Stage 3- Consensus. Stages 2 and 3 were held in Workshop format in virtual mode (W) Results Stage 1- Of the total 20 Google forms sent to the AU, 13 responses were received: 7 from National Universities and 6 from Private Universities. All participants agreed to be part of the consensus. Stage 2- W: 20 representatives from 10 AU participated. It began with a contextualizing conference, after which the representatives were divided into 5 groups to assess the agreements of each D. Stage 3- The Cariology Curriculum document was organized into 5 Domains, and 23 C and 31 I of clinical application were defined for teaching cariology. The contents and competences for each domain were agreed upon. The final document was sent to all W participants for their approval and dissemination in each AU involved Conclusion Cariology contents were defined for dentistry students at Universities in the Argentine Republic.

RESUMEN Objetivo Elaborar un documento de consenso de los contenidos y competencias de cariología en el currículo para las facultades/escuelas de odontología argentinas, a nivel del grado Materiales y Método El proceso de creación se efectuó en etapas: 1- Diagnóstico de situación (Formulario electrónico) e invitación a participar a las 20 unidades académicas (UA) donde se imparte la carrera de odontología. 2- Proceso de valoración de acuerdos de Contenidos (C) y Competencias (I) en los cinco dominios (D): D1: Ciencias Básicas; D2: Riesgo y diagnóstico de caries dental; D3: Toma de decisiones tratamientos no invasivos; D4: Toma de decisiones para el tratamiento invasivo y D5: Cariología basada en la evidencia a nivel comunitario. 3- Etapa de consenso. Las etapas 2 y 3 se efectuaron en formato de Workshop en modalidad virtual (W) Resultados Etapa 1: Del total de 20 formularios enviados a las UA se recibieron 13 respuestas (65%), 7 (53,8%) de Universidades Nacionales y 6 (46,1%) de gestión Privada. El 100% de los participantes estuvieron de acuerdo en formar parte del consenso. Etapa 2: W: Participaron 20 representantes de 10 UA. El proceso se inició con una conferencia contextualizadora, posteriormente los representantes fueron divididos en 5 grupos para la valoración de acuerdos de cada D. Etapa 3: El documento de658. 658.l Currículo en Cariología se organizó en 5 Dominios. Se definieron 23 C y 31 I de aplicación clínica para la enseñanza de la Cariología. Se consensuaron los contenidos y las competencias para cada uno de los dominios. El documento final fue enviado a todos los participantes del W para su aprobación y difusión en cada una de las UA involucradas Conclusión En base al trabajo realizado se determinó un consenso de competencias y contenidos en cariología para estudiantes de grado de Odontología, de las Universidades de la República Argentina.

https://doi.org/10.54589/aol.36/3/183

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