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Resumo Objetivo: O objetivo do estudo foi avaliar o alinhamento radiográfico na artroplastia total do joelho (ATJ) entre o pós-operatório imediato versus o tardio. Método: O estudo foi retrospectivo e observacional. A população do estudo foi composta por 200 pacientes com osteoartrite primária do joelho submetidos à artroplastia total do joelho. Resultados: Apenas a incidência em perfil evidenciou significância estatística entre as diferenças das medições das radiografias pós-operatória imediata da ATJ e com 3 meses de pós-operatório. Conclusão: O nosso estudo demonstrou uma variação entre a radiografia pós-operatória imediata da artroplastia total do joelho e a radiografia de controlo com 3 meses de pós-operatório apenas na incidência em perfil. Assim sendo, podemos inferir que a radiografia pós-operatória imediata na artroplastia total do joelho poderá ser um exame adequado para a análise pós-operatória.

Abstract Objective: The objective of the study was to evaluate the radiographic alignment in total knee arthroplasty (TKA) between the immediate versus the late postoperative period. Method: The study was retrospective and observational. The study population consisted of 200 patients with primary knee osteoarthritis undergoing total knee arthroplasty. Results: Only the lateral view showed statistical significance between the differences in measurements on the immediate postoperative radiographs of TKA and 3 months after the operation. Conclusion: Our study showed variation between the immediate postoperative radiograph of total knee arthroplasty and the control radiography 3 months after the operation only in the lateral view. Therefore, we can infer that immediate postoperative radiograph of total knee arthroplasty might be a suitable exam for postoperative analysis.

https://doi.org/10.25748/arp.30099

Microbiological Profi le of Periprosthetic Knee Infections in a Brazilian Unified Health System Hospital Specialized in Highly Complex Orthopedic Surgeries
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Mozella, Alan de Paula

; Assunção, Thales Nunes de

; Cobra, Hugo Alexandre de Araújo Barros

; Minamoto, Sandra Tie Nishibe

; Salim, Rodrigo

; Leal, Ana Carolina

Revista Brasileira de Ortopedia

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may 2023, Volume 58 N. 3 Pages 443 - 448

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective We studied the microbiological profile of periprosthetic knee infections treated in a Brazilian tertiary hospital. Methods The study included all patients undergoing revision surgery for total knee arthroplasty (RTKA) between November 2019 and December 2021, with a diagnosis of periprosthetic infection confirmed per the 2018 International Consensus Meeting (ICM) criteria. Results Sixty-two patients had a periprosthetic joint infection (PJI) per the 2018 ICM criteria. Cultures were monomicrobial in 79% and polymicrobial in 21% of cases. The most frequent bacterium in microbiological tissue and synovial fluid cultures was Staphylococcus aureus, observed in 26% of PJI patients. Periprosthetic joint infection with negative cultures occurred in 23% of patients. Conclusion Our results show the following: i) a high prevalence of Staphylococcus as an etiological agent for knee PJI; ii) a high incidence of polymicrobial infections in early infections; iii) the occurrence of PJI with negative cultures in approximately one fourth of the subjects.

Resumo Objetivo Identificar o perfil microbiológico das infecções periprotéticas do joelho tratadas em um hospital terciário brasileiro. Métodos Todos os pacientes submetidos à cirurgia de revisão de artroplastia total do joelho (RATJ), no período compreendido entre novembro de 2019 e dezembro de 2021, e que tiveram o diagnóstico de infecção periprotética confirmado de acordo com critérios do International Consensus Meeting (ICM) 2018, foram incluídos no estudo. Resultados Sessenta e dois pacientes foram diagnosticados com infecção periprotética (IAP) pelos critérios do International Consensus Meeting 2018. Culturas monomicrobianas foram identificadas em 79% e polimicrobianas em 21% dos casos. A bactéria mais frequentemente identificada nas culturas microbiológicas de tecidos e líquido sinovial foi o Staphylococcus aureus, presente em 26% dos pacientes com infecção periprotética. Infecções periprotéticas com culturas negativas ocorreram em 23% dos pacientes. Conclusão Nossos resultados evidenciam: i) alta prevalência de bactérias do gênero Staphylococcus como causadores da IAP do joelho; ii) a alta incidência de infecções polimicrobianas nas infecções precoces e iii) IAP com culturas negativas ocorre em, aproximadamente, um quarto dos pacientes.

https://doi.org/10.1055/s-0042-1758368

Clinical and pathological aspects of progressive hyperphosphatasemia associated with vacuolar hepatopathy and hepatocellular carcinoma in a Scottish Terrier bitch
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Ribeiro, Paula Reis

; Bianchi, Matheus Viezzer

; Lorenzett, Marina Paula

; Reis, Matheus de Oliveira

; Pöppl, Alan Gomes

; Pavarini, Saulo Petinatti

Ciência Rural

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2023, Volume 53 N. 1 elocation e20210689

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Hiperfosfatasemia é o aumento sérico de fosfatase alcalina, sendo que Scorrish Terriers estão predispostos a desenvolverem essa condição de patogênese desconhecida. Este trabalho descreve um caso de hiperfosfatasemia progressiva com hepatopatia vacuolar e carcinoma hepatocelular em um canino da raça Scottish Terrier. Uma cadela Scottish Terrier foi acompanhada clinicamente por cinco anos devido à hiperfosfatasemia persistente (até 5503 U/L), com achados ultrassonográficos e histológicos compatíveis com hepatopatia vacuolar, além de posterior desenvolvimento de carcinoma hepatocelular. O painel esteroidogênico realizado indicou aumento dos hormônios adrenocorticais, principalmente progesterona e androstenediona, consistente com diagnóstico de hipercortisolismo subdiagnosticado “atípico”. Devido ao prognóstico desfavorável, a eutanásia foi realizada e na necropsia, massas amarelas a vermelhas e multinodulares foram observadas no fígado, com diagnóstico de carcinoma hepatocelular pela análise histológica e imuno-histoquímica. A associação dos achados clínicos, de imagem, bioquímicos, do painel androgênico e patológicos permitiram caracterizar e confirmar um distúrbio progressivo no canino da raça Scottish Terrier associado ao aumento dos hormônios adrenocorticais.

ABSTRACT: Hyperphosphatasemia refers to an increase in alkaline phosphatase serum activity, and Scottish Terriers (STs) are predisposed to develop this condition of uncertain pathogenesis. This study describes a case of progressive hyperphosphatasemia with vacuolar hepatopathy and hepatocellular carcinoma (HCC) in a ST bitch. This dog had a five-year clinical follow-up with progressive hyperphosphatasemia (up to 5503 U/L) and with ultrasound findings and histologic diagnosis of vacuolar hepatopathy, in addition to posterior onset of HCC. A steroidogenic adrenal panel revealed an increase of adrenocortical hormones, especially progesterone and androstenedione, consistent with a subdiagnosed hypercortisolism. Euthanasia was elected and at necropsy, multinodular, yellow to red masses were observed in the liver, which were histologically and immunohistochemically defined as HCC. The association of the clinical, imaging, biochemical, adrenal panel and pathologic findings allowed to characterize and confirm a progressive disorder in this ST bitch associated with elevated adrenocortical hormones.

https://doi.org/10.1590/0103-8478cr20210689

National Vaccine Coverage Survey 2020: methods and operational aspects
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Barata, Rita Barradas

; França, Ana Paula

; Guibu, Ione Aquemi

; Vasconcellos, Maurício Teixeira Leite de

; Moraes, José Cássio de

; Teixeira, Maria da Gloria Lima Cruz

; Domingues, Carla Magda Alan

; Borges, Maria Fernanda de Souza Oliveira

; de Azevedo, Roberta Nogueira Calandrini

; de Oliveira, Consuelo Silva

; Oliveira, Andrea de Nazaré Marvão

; Canales, Ivy Thereza

; Nascimento, Valdir

; Queiroz, Rejane Christine de Souza

; Lima, Luísa Helena de Oliveira

; Ramos Jr, Alberto Novaes

; Barbosa, Jaqueline Caracas

; Mirabal, Isabelle Ribeiro Barbosa

; Meira, Meiruska

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria Denise de Castro

; Gurgel, Ricardo Queiroz

; de Carvalho, Martha Suely Itaparica

; Cesar, Tayñana

; Maciel, Ethel Leonor Noia

; da Gama, Silvana Granado Nogueira

; Luhm, Karin Regina

; Boing, Antônio Fernando

; Mengue, Sotero Serrate

; de Oliveira, Sandra Maria do Valle Leone

; Lima, Jaqueline Costa

; Teles, Sheila Araújo

; Caetano, Karlla Antonieta Amorim

; de Araújo, Wildo Navegantes

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230031

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Inquérito nacional de cobertura vacinal aos 12 e 24 meses de idade foi realizado para investigar as quedas nas coberturas a partir de 2016. Métodos: Amostra de 37.836 nascidos vivos das coortes de 2017 e 2018 residentes nas capitais, Distrito Federal (DF) e 12 cidades com mais de 100 mil habitantes, acompanhados nos primeiros 24 meses por registros nas cadernetas de vacinação. Setores censitários foram estratificados segundo condições socioeconômicas, e o mesmo número de crianças foi incluído para cada estrato. Calcularem-se coberturas vacinais de cada vacina e coberturas completas aos 12 e 24 meses, doses aplicadas, válidas e oportunas. Fatores familiares, maternos e da criança associados à cobertura foram pesquisados. Os motivos para não vacinar analisados foram: contraindicações médicas, dificuldades de acesso, problemas no funcionamento do programa e hesitação vacinal. Resultados: Os resultados preliminares mostram que menos de 1% das crianças não foram vacinadas, as coberturas pelo esquema completo são menores que 75% em todas as capitais e no DF, as vacinas com mais de uma dose perdem cobertura progressivamente, há diferenças entre os estratos socioeconômicos, favoráveis aos estratos mais altos em algumas cidades e aos estratos mais baixos em outras. Conclusão: Houve realmente redução da cobertura vacinal em todas as capitais e no DF para as crianças nascidas em 2017 e 2018, denotando piora na execução do Programa Nacional de Imunizações durante os anos de 2017 a 2019. O inquérito realizado não mensurou os impactos da pandemia de COVID-19 que podem ter reduzido ainda mais as coberturas vacinais.

ABSTRACT Objective: The national vaccination coverage survey on full vaccination at 12 and 24 months of age was carried out to investigate drops in coverage as of 2016. Methods: A sample of 37,836 live births from the 2017 or 2018 cohorts living in capital cities, the Federal District, and 12 inner cities with 100 thousand inhabitants were followed for the first 24 months through vaccine record cards. Census tracts stratified according to socioeconomic levels had the same number of children included in each stratum. Coverage for each vaccine, full vaccination at 12 and 24 months and number of doses administered, valid and timely, were calculated. Family, maternal and child factors associated with coverage were surveyed. The reasons for not vaccinating analyzed were: medical contraindications, access difficulties, problems with the program, and vaccine hesitancy. Results: Preliminary results showed that less than 1% of children were not vaccinated, full coverage was less than 75% at all capitals and the Federal District, vaccines requiring more than one dose progressively lost coverage, and there were inequalities among socioeconomic strata, favorable to the highest level in some cities and to the lowest in others. Conclusion: There was an actual reduction in full vaccination in all capitals and the Federal District for children born in 2017 and 2018, showing a deteriorating implementation of the National Immunization Program from 2017 to 2019. The survey did not measure the impacts of the COVID-19 pandemic, which may have further reduced vaccination coverage.

https://doi.org/10.1590/1980-549720230031

The frequency of psychotic symptoms in types of dementia: a systematic review
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Pessoa, Rebeca Mendes de Paula

; Maximiano-Barreto, Madson Alan

; Lambert, Letícia

; Leite, Érica Dayanne Meireles

; Chagas, Marcos Hortes Nisihara

Dementia & Neuropsychologia

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2023, Volume 17 elocation e20220044

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The frequency of psychotic symptoms in older adults is high, mainly in neurocognitive cognitions of the most varied etiologies. Objectives: This study aimed to review the studies that analyze the frequency of the types of delusions, hallucinations, and misidentifications in dementia conditions of different etiologies. Methods: A systematic review was conducted on August 9, 2021, in the PubMed, PsycInfo, Embase, Web of Science, and Scopus databases with the following descriptors: (dementia OR alzheimer disease OR dementia with Lewy bodies OR frontotemporal dementia OR mixed dementia OR vascular dementia OR major neurocognitive disorder OR parkinson disease dementia) AND (psychotic symptoms OR psychosis OR hallucinations OR delusions OR psychopathology OR misidentification) AND (prevalence OR epidemiology). Results: A total of 5,077 articles were found, with a final inclusion of 35. The overall frequency of psychotic symptoms ranged from 34 to 63% in dementia conditions of the most varied etiologies. Alzheimer’s disease (AD) presents more delusions and hallucinations and has a higher frequency regarding the presence of misidentifications. On the contrary, Dementia with Lewy bodies (DLB) seems to present more hallucinations, even auditory, when compared to the other dementias, concomitantly with delusions. Vascular and frontotemporal dementia present fewer psychotic symptoms than DLB and AD. Conclusions: We identified a gap in the literature on the description of the psychotic symptoms of dementia, mainly in those of non-AD etiologies. Studies that assess the neuropsychiatric symptoms of dementias deeply might contribute in a more definite manner to the causal diagnosis of dementia.

RESUMO A frequência de sintomas psicóticos em idosos é alta, principalmente em cognições neurocognitivas das mais variadas etiologias. Objetivos: Revisar os estudos que analisam a frequência dos tipos de delírios, alucinações e erros de identificação em quadros demenciais de diferentes etiologias. Métodos: Foi realizada uma revisão sistemática em 9 de agosto de 2021, nas bases de dados PubMed, PsycInfo, Embase, Web of Science e Scopus, com os seguintes descritores: (demência OR doença de alzheimer OR demência com corpos de Lewy OR demência frontotemporal OR demência mista OR vascular demência OU transtorno neurocognitivo maior OU demência da doença de Parkinson) E (sintomas psicóticos OU psicose OU alucinações OU delírios OU psicopatologia OU identificação errônea) E (prevalência OU epidemiologia). Resultados: Foram encontrados 5.077 artigos, com inclusão final de 35. A frequência geral de sintomas psicóticos foi de 34 a 63% em quadros demenciais das mais variadas etiologias. A doença de Alzheimer (DA) apresenta mais delírios, alucinações e maior frequência quanto à presença de erros de identificação. Por outro lado, a demência com corpos de Lewy (DCL) parece apresentar mais alucinações, inclusive auditivas, quando comparada às demais demências, concomitantemente aos delírios. As demências vascular e frontotemporal apresentam menos sintomas psicóticos do que a DCL e a DA. Conclusões: Identificamos lacuna na literatura quanto à descrição dos sintomas psicóticos das demências, principalmente naquelas de etiologia não DA. Estudos que aprofundem os sintomas neuropsiquiátricos das demências podem contribuir de forma mais definitiva para o diagnóstico causal da demência.

https://doi.org/10.1590/1980-5764-dn-2022-0044

Efficacy assessment of an intramammary formulation based on soluble polypyrrole in cows with experimentally induced mastitis
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Alves, Ana Paula Pereira

; Amaral, Marcos Pinheiro do

; Silva, Diego César Nunes da

; Souza, Renata de Faria Silva

; Reis, Sílvio Alan Gonçalves Bomfim

; Silva Júnior, Fernando Antônio Gomes da

; Oliveira, Helinando Pequeno de

; Peixoto, Rodolfo de Moraes

; Costa, Mateus Matiuzzi da

Ciência Rural

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2023, Volume 53 N. 9 elocation e20220047

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

RESUMO: Considerando a necessidade de terapias alternativas para a mastite bovina, uma inflamação, normalmente de causa infecciosa, de alta prevalência e de alto impacto econômico nas fazendas leiteiras, avaliou-se a eficácia antimicrobiana, in vivo, de uma formulação intramamária à base de polipirrol (PPy) solúvel, um polímero condutor promissor para aplicações biomédicas, especialmente como potente antibacteriano. Neste ensaio, quartos mamários de vacas holandesas sadias (n = 8) foram inoculados com Staphylococcus aureus e tratados, por via intramamária, com formulação experimental à base de PPy solúvel (5%) e com formulação comercial à base de sulfato de gentamicina. O efeito desses tratamentos foi avaliado com a realização de lactoculturas, da Contagem Bacteriana Total (TBC), da Contagem de Células Somáticas (SCC) e da análise da composição do leite das amostras obtidas de quartos mamários, em sete momentos experimentais. Avaliação hematológica dos animais também foi realizada. A aplicação intramamária de três doses da formulação experimental à base de PPy solúvel resultou em maiores log/mL da TBC e da SCC quando comparadas ao grupo controle positivo e ao grupo que recebeu sulfato de gentamicina. A administração da formulação experimental não induziu alterações na composição do leite e nos parâmetros hematológicos. Alguns fatores farmacocinéticos e farmacodinâmicos do PPy solúvel podem ser atribuídos a ineficácia antimicrobiana da pomada experimental. Outras pesquisas devem ser realizados em prol do desenvolvimento de formulações que permitam a atuação antibacteriana do PPy solúvel no ambiente intramamário de vacas leiteiras.

ABSTRACT: Given the need for alternative therapies for bovine mastitis, an infectious disease of high prevalence and significant economic impact in dairy farms, this study evaluated the in vivo antimicrobial efficacy of an intramammary formulation based on soluble polypyrrole (PPy), a promising conductive polymer for biomedical applications, especially as an effective antimicrobial agent. In this assay, mammary quarters of healthy Holstein Friesian cows (n = 8) were inoculated with Staphylococcus aureus and treated, via the intramammary route, with an experimental formulation based on soluble PPy (5%) and a commercial formulation based on gentamicin sulfate. The effect of these treatments was evaluated based on milk cultures, Total Bacterial Count (TBC), Somatic Cell Count (SCC), and milk composition analysis of mammary quarter samples in seven experimental moments. In addition, hematological evaluations of the animals were also performed. The intramammary application of three levels of the experimental formulation based on soluble PPy resulted in higher log/mL of the TBC and SCC compared to a positive control group and a group that received gentamicin sulfate. The experimental formulation did not induce changes in milk composition or in hematological parameters. Certain factors related to pharmacokinetics, such as the type of carrier used in the formulation and the pharmacodynamics of soluble PPy, may have contributed to the antimicrobial ineffectiveness of the experimental formulation. The results of this study neither define nor decrease the antimicrobial potential of soluble PPy. Further research is required to develop formulations that enable the antibacterial action of soluble PPy in the intramammary environment of dairy cows.

https://doi.org/10.1590/0103-8478cr20220047

General Approach to Acute Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA): A Systematic Review
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Oliveira, Marcos Aurélio Barboza de

; Ósti, Alan Vinicius Gamero

; Cavalheiro, Bruno Vargas Teixeira

; Naves, Déborah Barbosa

; Oliveira, Emanuelle Ribeiro de

; Campos, Gabriel Freitas de

; Lobo, Gabriel Mael Sussuarana Silva

; Oliveira, Gabriely de

; Mainardi, Marcela Paula

; Guimarães, Marília Cardoso

; Barbosa, Robert Filipe

; Fé, Vilian Veloso de Moura

International Journal of Cardiovascular Sciences

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2023, Volume 36 elocation e20220046

Abstract: En | Text: En | PDF: En

Abstract Background Acute myocardial infarction (AMI) without obstructive coronary arteries (MINOCA) is a medical condition of great relevance, with clinical characteristics of AMI, but without evidence of coronary artery obstruction. The mechanism involved in the pathophysiology of the disease and its possible etiologies are important objects of study due to their impact on the morbidity and mortality of affected patients. Objectives The aim of this study was to systematically review MINOCA and its characteristics, with emphasis on the clinical profile of patients, etiology, pathophysiology, diagnosis, and treatment of the syndrome. Methods Relevant articles related to MINOCA were analyzed in the PubMed and LILACS databases. In the initial search stage, 619 eligible articles were obtained, with final inclusion criteria being: original systematic reviews with clinical, epidemiological, diagnostic, or treatment data on MINOCA, published in Portuguese or English, with an abstract, and a publication date limit of September 2020. Results A total of 10 articles classified as systematic reviews that considered clinical data on MINOCA were included in this review. Conclusion After analyzing various literature, the present study provided a tool to better understand MINOCA, not only regarding its casuistry but also in grouping parameters and information that contribute to a healthy approach to this clinical situation. It was possible to identify and better outline the clinical profile of patients who presented this condition and the use of appropriate tools for correct diagnosis and ideal treatment.

https://doi.org/10.36660/ijcs.20220046

National Vaccine Coverage Survey 2020: methods and operational aspects
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Barata, Rita Barradas

; França, Ana Paula

; Guibu, Ione Aquemi

; Vasconcellos, Maurício Teixeira Leite de

; Moraes, José Cássio de

; Teixeira, Maria da Gloria Lima Cruz

; Domingues, Carla Magda Alan

; Borges, Maria Fernanda de Souza Oliveira

; de Azevedo, Roberta Nogueira Calandrini

; de Oliveira, Consuelo Silva

; Oliveira, Andrea de Nazaré Marvão

; Canales, Ivy Thereza

; Nascimento, Valdir

; Queiroz, Rejane Christine de Souza

; Lima, Luísa Helena de Oliveira

; Ramos Jr, Alberto Novaes

; Barbosa, Jaqueline Caracas

; Mirabal, Isabelle Ribeiro Barbosa

; Meira, Meiruska

; Antunes, Maria Bernadete de Cerqueira

; Teixeira, Maria Denise de Castro

; Gurgel, Ricardo Queiroz

; de Carvalho, Martha Suely Itaparica

; Cesar, Tayñana

; Maciel, Ethel Leonor Noia

; da Gama, Silvana Granado Nogueira

; Luhm, Karin Regina

; Boing, Antônio Fernando

; Mengue, Sotero Serrate

; de Oliveira, Sandra Maria do Valle Leone

; Lima, Jaqueline Costa

; Teles, Sheila Araújo

; Caetano, Karlla Antonieta Amorim

; de Araújo, Wildo Navegantes

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230031

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720230031

From coconut waste to the production of cementitious composites as an alternative for civil construction
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Silva, Fernanda Monique da

; Scatolino, Mario Vanoli

; Paula, Edgley Alves de Oliveira

; Almeida, Vanessa Gentil de Oliveira

; Albuquerque, Felipe Bento de

; Vieira, Ricardo Alan da Silva

; Souza, Joalis Barbalho de

; Pedrosa, Talita Dantas

; Rodolfo Junior, Francisco

; Melo, Rafael Rodolfo de

Matéria (Rio de Janeiro)

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2023, Volume 28 N. 3 elocation e20220146

Abstract: En | Text: En | PDF: En

ABSTRACT Economic development based on cleaner industrial technologies has been increasingly studied in recent years. Cementitious composites reinforced with lignocellulosic fibers can be a sustainable alternative for use in engineering. The study aimed to evaluate the technological properties of cementitious composites produced from natural and industrial coconut fiber to compare the reinforcement with wood particles. Physical tests (density, water absorption, and thickness swelling) and mechanical tests (static bending) were carried out in four treatments, which varied the fiber and cement contents. It was found that treatment with natural coconut fiber had the lowest density value, 0.59 g/cm3, and treatment with industrial coconut fiber had the lowest water absorption value for the times and times of 2 and 24 h, 0.19, and 0.38%, respectively, and the treatment with wood particles, the highest values of modulus of elasticity and rupture, 1,897 MPa and 2.44 MPa. The study of the use of lignocellulosic materials as protection in cementitious composites is essential for applications in building constructions to reduce the environmental impacts generated by the generation of waste and use of non-renewable materials and to promote sustainable development.

https://doi.org/10.1590/1517-7076-rmat-2023-0146

10.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

11.

Efeito da temperatura e pressão nas propriedades da liga de titânio Ti-6Aℓ-4V produzida a partir da metalurgia do pó
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Silva Vieira, Ricardo Alan da

; Fonseca, Erbenia Taciane Fernandes da

; Silva Júnior, Manoel Quirino da

; Oliveira Paula, Edgley Alves de

; Silva, Fernanda Monique da

; Albuquerque, Felipe Bento de

; Souza, Joalis Barbalho de

; Rusch, Fernando

; Scatolino, Mário Vanoli

; Melo, Rafael Rodolfo de

Matéria (Rio de Janeiro)

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2023, Volume 28 N. 3 elocation e20230196

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Were characterized microstructurally and mechanically the Ti-6Aℓ-4V alloy obtained through powder metallurgy in an uncontrolled atmosphere, varying the sintering parameters, arose. The samples were compacted in a uniaxial press at 874 MPa, 999 MPa, and 1124 MPa, and sintered without a protective atmosphere or vacuum, at 675 °C, 750 °C, and 850 °C. When sintering the material, the oxides influenced the results due to titanium’s high affinity for interstitial elements, promoting increased density and high hardness values. Based on the results, the treatment carried out at a pressure of 1124 MPa and a temperature of 750 °C showed the highest hardness in the beta phase (β), with a value of 1165.1 HV. In the alpha phase (α), the highest value was 1321.3 HV, presented by the treatment performed at a pressure of 999 MPa and a temperature of 850 °C. The high hardness values observed in the alloy are associated with the reinforcement promoted by the dissolution of Fe atoms. Materials with high hardness values use in the aerospace and biomedical industries, which always look for better mechanical resistance results, thus increasing their products’ useful life and applicability.

RESUMO Foram caracterizadas micro estruturalmente e mecanicamente a liga Ti-6Aℓ-4V obtida através da metalurgia do pó em atmosfera não controlada variando os parâmetros de sinterização. As amostras foram compactadas em uma prensa uniaxial à 874 MPa, 999 MPa e 1124 MPa, e sinterizadas sem atmosfera protetora ou vácuo, nas temperaturas de 675 °C, 750 °C e 850 °C. Ao sinterizar o material, houve influência dos óxidos nos resultados devido à alta afinidade que o titânio tem por elementos intersticiais, promovendo um aumento na densidade e elevados valores de dureza. A partir dos resultados verificou-se que o tratamento realizado na pressão de 1124 MPa e temperatura de 750 °C foi o que apontou a maior dureza na fase beta (β), sendo o valor de 1165,1 HV. Na fase alfa (α), o maior valor foi de 1321,3 HV, apresentado pelo tratamento realizado na pressão de 999 MPa e temperatura de 850 °C. Os elevados valores na dureza observados na liga estão associados ao reforço promovido pela dissolução átomos de Fe. Materiais com elevada dureza possuem uma vasta aplicação nas indústrias aeroespaciais e biomédicas, que buscam sempre por melhores resultados de resistência mecânica, aumentando assim a vida útil e a aplicabilidades de seus produtos.

https://doi.org/10.1590/1517-7076-rmat-2023-0196

12.

[SciELO Preprints] - PROFESSIONAL TRAINING OF THE GRADUATE IN CHEMISTRY: PERSPECTIVES FOR THEIR FUTURE FIELD OF ACTIVITY
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Castro, Alan Stampini Benhame de Paula, Hauster Maximiler Campos de Chagas, Francielle De Oliveira Benhami, Bruna Medina

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Publication date: 2022-10-20

Abstract: En Es Pt

This work is part of a case study on newly graduated students with a maximum of 5 years of the Degree in Chemistry at the Universidade do Estado de Minas Gerais – Ubá unit - MG. We analyzed the school and academic trajectories as well as the future performance in the job market so far. We adopted a qualitative approach seeking the reality of the professional profile of the graduate in Chemistry. The exploratory research method was used through the application of two semi-structured questionnaires aimed at professionals trained in a degree in Chemistry who work or not as teachers. In our analysis, the vast majority, about 85% of respondents, have a paid activity related to chemistry, either as a teacher or chemist in the industry. The academic conditions of the institution were analyzed according to the academic preparation of the graduates. Highlights, such as the integration of graduates into the academic and industrial labor market, are favorable to the academic quality of the institution. The portraits point to a formative trajectory between social and academic integration, favored by the teaching, research and extension projects offered at the university.

Este estudio de caso se trata de estudiantes recién graduados con un máximo de 5 años de la Licenciatura en Química de la Universidade do Estado de Minas Gerais - unidad de Ubá - MG. Analizamos las trayectorias escolares y académicas, así como el desempeño futuro en el mercado laboral hasta el momento. Adoptamos un enfoque cualitativo buscando la realidad del perfil profesional del licenciado en Química. Se utilizó el método de investigación exploratoria mediante la aplicación de dos cuestionarios semiestructurados dirigidos a profesionales formados en la carrera de Química que se desempeñen o no como docentes. En nuestro análisis, la gran mayoría, alrededor del 85% de los encuestados, tiene una actividad remunerada relacionada con la química, ya sea como docente o químico en la industria. Se analizaron las condiciones académicas de la institución de acuerdo a la preparación académica de los egresados. Destacados, como la integración de los egresados al mercado laboral académico e industrial, son favorables a la calidad académica de la institución. Los retratos apuntan a una trayectoria formativa entre la integración social y académica, favorecida por los proyectos de docencia, investigación y extensión que ofrece la universidad.

Este estudo de caso é sobre alunos recém-formados com um máximo de 5 anos do curso de Licenciatura em Química pela Universidade do Estado de Minas Gerais – unidade de Ubá – MG. Analisamos as trajetórias escolares e acadêmicas bem como a futura atuação no mercado de trabalho até o momento. Adotamos uma abordagem qualitativa buscando a realidade do perfil profissional do formado em Licenciatura em Química. Utilizou-se o método de pesquisa exploratória através da aplicação de dois questionários semiestruturados direcionados a profissionais formados em Licenciatura em Química que atuam ou não como professores. Em nossa análise a imensa maioria, cerca de 85% dos entrevistados, exercem atividade remunerada relacionada à química, seja como professor ou químico na indústria. Analisou-se as condições acadêmicas da instituição de acordo com o preparo acadêmico dos licenciados. Os pontos em destaque, como a integração dos licenciados no mercado de trabalho acadêmico e industrial, são favoráveis a qualidade acadêmica da instituição. Os retratos apontam uma trajetória formativa entre a integração social e acadêmica, favorecida pelos projetos de ensino, pesquisa e extensão oferecidos na universidade.

https://doi.org/10.1590/SciELOPreprints.4416

13.

Midterm Radiographic Results and Reoperations of Tantalum Trabecular Metal Cones in Knee Arthroplasties
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Minamoto, Sandra Tie Nishibe

; Silva, Luís Felipe Tupinambá da

; Faria, José Leonardo Rocha de

; Cobra, Hugo Alexandre de Araujo Barros

; Palma, Idemar Monteiro da

; Mozella, Alan de Paula

Revista Brasileira de Ortopedia

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oct 2022, Volume 57 N. 5 Pages 734 - 740

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo O manejo da perda óssea representa um grande desafio em cirurgias de revisão de artroplastia do joelho (rATJ) e em artroplastias totais do joelho (ATJ) primárias complexas. O objetivo do presente estudo foi avaliar os resultados em médio prazo (seguimento mínimo de 5 anos) das reconstruções de joelho nas quais cones de metal trabecular (MT) de tântalo foram utilizados para tratamento de defeitos ósseos tipos 2 e 3, de acordo com a classificação proposta pela Anderson Orthopaedic Research Institute (AORI). Métodos Feita análise retrospectiva dos prontuários dos pacientes operados entre julho de 2008 e novembro de 2014, coletando-se os seguintes dados: idade, gênero, lateralidade, índice de massa corporal, etiologia da artrose, comorbidade, classificação AORI da falha óssea, causa da revisão da artroplastia total do joelho, reinternações, reoperações, complicações peri- e pós-operatórias, ocorrência de osteointegração radiográfica e manutenção da função de suporte do MT. Resultados Foram avaliados 11 pacientes com tempo médio de seguimento de 7,28 anos (desvio padrão [DP] = 1,88; variação = 5,12–10 anos), sendo que 1 paciente foi submetido a artroplastia primária, 6 a artroplastia de revisão e 4 a segunda revisão de artroplastia (re-revisão). Três pacientes necessitaram de quatro reoperações devido a complicações com a ferida operatória, a lesão do mecanismo extensor e a soltura do componente femoral. Sinais de osteointegração dos cones trabeculados foram observados em todos os pacientes. Não observamos migração do cone de MT ou dos componentes protéticos. Conclusão Os cones metafisários de tântalo foram capazes de prover suporte estrutural eficiente aos implantes protéticos com sinais radiográficos de osteointegração em médio prazo.

Abstract Objective The management of bone loss represents a challenge in revisions of total knee arthroplasty (rTKA) and in complex primary total knee arthroplasties (TKAs). The purpose of the present study was to evaluate the midterm outcomes (5-year minimum follow-up) of knee reconstructions with tantalum trabecular metal (TM) cones on bone defects Anderson Orthopaedics Research Institute (AORI) 2 and 3. Materials and MethodsA retrospective analysis of the medical records of patients operated on between July 2008 and November 2014 was performed, collecting the following data: age, gender, laterality, body mass index, etiology of arthrosis, comorbidities, AORI classification of bone defects, causes for revision, readmissions, reoperations, perioperative and postoperative complications, radiographic signs of osteointegration, and maintenance of the TM support. Results A total of 11 patients with a mean follow-up of 7.28 years (standard deviation [SD] = 1.88; range = 5.12–10 years) was evaluated, with 1 patient operated upon for a primary arthroplasty, 6 for revision arthroplasties, and 4 for a second revision arthroplasty (re-revision). There were complications with the surgical wound, injury to the extensor mechanism and loosening of the femoral component in three of the patients that led to the necessity of four procedures due to complications with the surgical wound, injury to the extensor mechanism and loosening of the femoral component. Radiological signs of osteointegration of the trabecular cones were observed in all patients. We did not observe migration of the TM cones or the prosthetic components in the sample. Conclusion The tantalum metaphyseal cones were able to provide efficient structural support to prosthetic implants with radiographic signs of osteointegration in the medium term.

https://doi.org/10.1055/s-0041-1739465

14.

Taller de concordancia en la evaluación de imágenes capilaroscópicas
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Izaguirre, Pía

; Romanini, Félix Enrique

; Mamani, Marta

; Montoya, Sandra Fabiana

; Toibar, Javier

; Catalán Pellet, Santiago

; Sirera, Ana Irene

; Dueñas, Lelly

; Cucchiaro, Natalia

; Cousseau, Mario

; Orellana González, Carlos Alberto

; Yucra, Demelza

; Tralice, Elda Rossella

; Raschia, Alan Juan

; Molina, María Josefina

; Lencia, María Verónica

; Espasa, Gabriela Vanesa

; Linarez Martínez, Miguel Alex

; Castro Coello, Vanesa Viviana

; García, Aldo

; Velloso, María Sofía

; González, Paula Alejandra

; German, Noelia Fernanda

; Conti, Silvana

; Savy, Florencia

; Morbiducci, Julieta Silvana

; Rivero, Mariano

; Saavedra, Leandro José

; Sabelli, Mirtha Rosa

; Rebak, Jonathan Eliseo

; Rojas Tessel, Romina

; Sorrentino, Laura

; Gervasoni, Viviana Lorena

; Marcantoni, María Beatriz

; Gervilla de Cafrune, Ana Lía

; Got, Julio

; Sánchez, Gabriela

; Castorino, Gerardo

; García, Lucila

; Sansinanea, Pierina

; Tamborenea, María Natalia

Revista argentina de reumatología

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oct 2022, Volume 33 N. 4 Pages 223 - 227

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción: la capilaroscopia es un método no invasivo que permite observar la microvasculatura en el área periungueal. Los resultados informados pueden ser altamente variables entre distintos observadores. A lo largo del tiempo surgieron métodos cuantitativos y semicuantitativos para mejorar la reproducibilidad. Objetivos: conocer el nivel de acuerdo intra e interobservador al informar los diferentes patrones capilaroscópicos en individuos con diferente nivel de entrenamiento. Materiales y métodos: estudio de corte transversal. Participaron médicos reumatólogos especialistas y en formación que habían realizado previamente un curso virtual de capacitación en capilaroscopia. Recibieron 40 imágenes capilaroscópicas proyectadas en una presentación de PowerPoint y debían responder a través de un cuestionario digital. Se evaluó la concordancia de respuestas intra e interobservador. Resultados: se encontró un alto nivel de concordancia global con un kappa 0,66 IC 95% (0,63-0,70) p<0,0000. También en otros grupos como reumatólogos en formación: kappa 0,65 IC 95% (0,60-0,71) p=0,0000, y médicos reumatólogos: kappa 0,67 IC 95% (0,62-0,72) p=0,0000. Conclusiones: el nivel de concordancia encontrado fue globalmente alto, independientemente del nivel de entrenamiento de los profesionales, y de ser o no reumatólogo. La concordancia fue superior cuando se comparó a quienes tenían más de 4 años de experiencia en la realización de videocapilaroscopia.

Abstract Introduction: videoapillaroscopy is a non-invasive method that allows the observation of the microvasculature in the periungual area. Reported results can be highly variable between different observers. Over time, quantitative and semi-quantitative methods emerged to improve reproducibility. Objetives: to know the level of intra and interobserver agreement when reporting the different capillaroscopic patterns in individuals with different levels of training. Materials and methods: cross section study. Specialist rheumatologists and those in training who had previously completed a virtual capillaroscopy training course participated. They received 40 capillaroscopic images projected in a PowerPoint presentation and had to issue their response through a digital questionnaire. Concordance of intra and interobserver responses was evaluated. Results: a high level of global agreement was found with a kappa 0.66 CI 95% (0.63-0.70) p<0.0000, also in other groups such as rheumatologists in training: kappa 0.65 CI 95% (0.60-0.71) p=0.0000, physicians rheumatologists: kappa 0.67 95% CI (0.62-0.72) p=0.0000. Conclusions: the level of agreement found was globally high, regardless of the level of training of the professionals, and whether or not they were a rheumatologist. Concordance was higher when compared to those who had more than 4 years of experience performing videocapillaroscopy.

https://doi.org/10.47196/rar.v33i4.709

15.

[SciELO Preprints] - PODCAST AS EDUCATIONAL TOOL IN THE COVID-19 PANDEMIC
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Rodrigues, Caio Henrique Pinke Ferreira-Júnior, Angelo Alves Cintra, Álefe Saloum Luiz, Alan Vinícius Assunção Fernandes, Ana Paula Morais Bruni, Aline Thais Nascimento, Ana Carolina Dalbó do

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Publication date: 2022-04-14

Abstract: En Pt

In this work, the objective was to identify podcasts applied to education or that could be used for this purpose, that had the COVID-19 pandemic as a central theme or that encompassed the subject in their contents, in order to suggest the use of this tool as a methodology complement in the teaching-learning process. 36 podcasts were identified and evaluated according to the proposed taxonomy. Of these, 19 made up the final sample. It was observed that the contents covered different levels of education, which demonstrates potential application in the face of new educational challenges. Nevertheless, podcasts cross different areas of knowledge, allowing for more effective interdisciplinarity. It is thus understood that podcasts can be used at different times and with different teaching methodologies. In addition, the tool enables the inclusion of different peculiarities in the teaching-learning process and makes the pedagogical process plural.

Neste trabalho, objetivou-se identificar podcasts aplicados à educação ou que pudessem ser utilizados com esta finalidade, que tivessem a pandemia da COVID-19 como temática central ou que englobassem o assunto em seus conteúdos, com vistas a sugerir o uso desta ferramenta como metodologia complementar no processo de ensino-aprendizagem. Foram identificados e avaliados 36 podcasts conforme a taxonomia proposta. Destes, 19 compuseram a amostra final. Observou-se que os conteúdos abrangiam diversos níveis de ensino, o que demonstra potencial aplicação frente aos novos desafios educacionais. Não obstante, os podcasts atravessam diferentes áreas do conhecimento permitindo uma interdisciplinaridade mais efetiva. Entende-se assim que os podcasts podem ser utilizados em diferentes momentos e com diferentes metodologias de ensino. Além disso, a ferramenta possibilita a inclusão de diferentes peculiaridades no processo de ensino-aprendizagem e torna o processo pedagógico plural.

https://doi.org/10.1590/SciELOPreprints.3943

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