Abstract As tourism research focuses on experience, memorable tourism experience (MTE) is gaining importance among academia and destination managers. However, only limited studies have examined the antecedents and consequences of MTE. Therefore, this study will investigate human emotions with their underlying factors in influencing MTE to cater to revisit intention in tourists. For this study, CFA-SEM is applied to a sample of 1120 tourists from central India to access the empirical relationships. The empirically validated model confirmed the significant relationships among human emotions, MTE, and revisit intention. Results suggested that human emotions significantly influence MTE, which is reflected as revisit intention in tourists. Findings also confirmed the moderating role of the perceived risk of COVID-19 further, exploring the health-linked effects on tourism. This study will help the researchers and destination managers make more informed decisions and strategies to make tourism destinations more sustainable by incorporating human emotions as a significant factor in influencing the tourism experience. The findings will also help destination managers in making tourism more risk-averse.

Resumo A experiência memorável de turismo (EMT) tem ganho importância entre a academia e os gestores de destinos. No entanto, apenas poucos estudos examinaram os antecedentes e consequências da EMT. Neste sentido, este estudo investigará as emoções humanas e os fatores subjacentes na influência da EMT para atender à intenção de revisitar dos turistas. Para este estudo, CFA-SEM é aplicado a uma amostra de 1120 turistas do centro da Índia para acessar as relações empíricas. O modelo empiricamente validado confirmou as relações significativas entre emoções humanas, EMT e intenção de revisitar. Os resultados também confirmaram o papel moderador do risco percebido da COVID-19, explorando os efeitos relacionados com a saúde no turismo. Esta pesquisa ajudará os investigadores e os gestores de destinos a tomar decisões e estratégias mais informadas para tornar os destinos turísticos mais sustentáveis, incorporando as emoções humanas como um fator significativo na influência da experiência turística. Os resultados também ajudarão os gestores de destinos a tornar o turismo mais seguro.

Abstract In this article, a novel Compact Circularly Polarized Antenna with a notched circular Electromagnetic Band Gap (NCEBG) structure is put forward. This proposed structure comprises of a truncated rectangular patch antenna having its ground plane defected by slots etched on it to achieve compactness and wide impedance bandwidth. Electromagnetic Band Gap structures have the attractive feature of in-phase reflection and stopband creation for surface waves, enabling the surface waves to be suppressed; this, in turn, leads to enhanced performance of the antenna when loaded with such structures. For enhancing the functioning of the antenna with regard to its impedance bandwidth, axial ratio bandwidth and gain, seven NCEBG's are etched on the substrate which surrounds the truncated patch. Additionally, the antenna proposed in this research exhibits compactness with a low profile of 0.473 λo x 0.473 λo x 0.039 λo (λo at center frequency of 7.46GHz represents free space wavelength). The measured outcomes of the prototype-fabricated antenna match well with the results of the simulation, showing 3-dB axial ratio bandwidth of 13.66% and an impedance bandwidth of 73.29% having a peak gain of 7.32dBi in the operating band. The improved functioning of the proposed antenna marks it as a favorable applicant for wireless communication techniques and thus finding its application in various ways.

BACKGROUND: Logistics is an integral component for success of an organisation. So correct decision on express logistics procurement plays a critical role in success in delivering right product at right place and right time. Procurement of express logistics service is not very straight forward, instead it requires evaluation of multiple factors OBJECTIVE: The objective of this research is to create a framework of influencing factor on express logistics buying decision METHOD: For the study, researchers has adopted secondary research along with primary research with group of 14 subject matter experts in field of Indian logistics sector. A group of experts comprises of senior managers, consultants and academicians with deep understanding of subject. We have used ISM (Interpretive Structural Modelling) and Cross Impact Matrix Multiplication Applied to Classification (MICMAC) to drive conceptual framework for logistics buying decision RESULTS: Framework shows that the decision making in logistics procurement should be highly driven by factors like network reach of Logistics Service Provider (LSP), technology followed by information sharing and strategic partnership. While service quality and cost of logistics remains as frontend factors in logistics procurement decision CONCLUSION: The model output clearly suggests that final objective in buying process of express logistics is driven towards lower cost and improved service level, but it is driven by factors which directly adds value in supply chain like time to market and reverse logistics, technology and reach CONTRIBUTION: The model provides a framework for practitioners, which can enable them in decision making process of logistics procurement

Abstract The present study aimed to identify the bioactive constituents in the chloroform extract of H. spicatum rhizomes (HS-RCLE), further evaluated for its in-vitro pesticidal activities validating via molecular docking techniques. GC/MS analysis of HS-RCLE identified 14 compounds contributing 84.1 % of the total composition. The extract was dominated by oxygenated sesquiterpenes (43.1 %) with curcumenone (25.2 %) and coronarin E (14.8 %) as the major compounds. The extract recorded 89.4 % egg hatchability inhibition and 82.6 % immobility of Meloidogyne incognita, 66.7 % insecticidal activity on Spodoptera litura, 100 % phytotoxic activity on Raphanus raphanistrum seeds, and 74.7 % anti-fungal activity on Curvularia lunata at the respective highest dose studied. The biological activities were furthermore validated by using docking studies on certain proteins/enzymes namely acetylcholinesterase (PBD ID: IC2O), carboxylesterase (PDB ID: 1CI8), acetohydroxyacid synthase (PBD ID: 1YHZ) and trihydroxy naphthalene reductase (PBD ID: 3HNR). The bioactivity of the major constituents of the extract was predicted with the help of in silico PASS studies. HS-RCLE was observed to be a viable alternative source of natural pesticidal agents and paves the way for further studies on its mechanistic approaches and field trials to ascertain its pesticidal studies.

Abstract The proposed study was to determine if the silver nanoparticles can be used as potential antimicrobial agents and can replace the use of conventional antibiotics in semen without affecting the motility and fertility of semen. The silver nanoparticles prepared by chemical reduction method were confirmed by determination of the wavelength of surface plasmon resonance peak and further characterized using Zetasizer by determining their size, polydispersity index, and zeta potential. The nanoparticles were assessed for antibacterial activity and their concentration was optimized for use in semen extender for cryopreservation. Cryopreserved semen was further evaluated for seminal parameters, antioxidant parameter, and microbial load. Prepared silver NPs showed a plasmon resonance peak at 417 nm wavelength. NPs were found to possess antibacterial activity and were supplemented in semen extender @ 125 and 250 µg/ml for semen cryopreservation. There was a significant increase in pre and post-freezing motility and other seminal parameters. The microbial load of frozen-thawed semen of control and supplemented groups were well within the permissible limits. Lipid peroxidation levels were reduced in NPs supplemented groups, and reactive oxygen species (ROS) levels were significantly reduced in semen supplemented with 125 µg/ml NPs. Thus it can be conclude that silver NPs can be successfully used as a substitute for antibiotics in cattle bull semen cryopreservation with good antimicrobial activity and no adverse effects on sperm characteristics.

Resumen Introducción: El manejo hemodinámico intraoperatorio y la analgesia postoperatoria durante la cirugía artroscópica de hombro sigue siendo un desafío. Aun cuando el bloqueo interescalénico del plexo braquial (BIE) se considera ideal para la anestesia del hombro, a diferencia del uso de la dexmedetomidina intravenosa (IV), el BIE requiere destreza y maestría. Objetivo: El presente estudio aleatorizado se llevó a cabo para observar la eficacia de la infusión de dexmedetomidina que es menos invasiva y exige menos destreza que el bloqueo del plexo. Metodología: Todos los pacientes programados para cirugía artroscópica electiva de hombro bajo anestesia general, se asignaron o bien al grupo DEX, para recibir un bolo de dexmedetomidina IV de 0,5 mcg/kg en 20 minutos, seguido de una infusión de 0,5 mcg/kg/hora que se detuvo 30 minutos antes del final de la cirugía; o, al grupo BLOQUEO al cual se le administró un BIE ecoguiado con 20ml debupivacaína 0,25%. El desenlace primario evaluado fue la hemodinamia intraoperatoria; los desenlaces secundarios fueron el dolor postoperatorio inmediato, la condición operatoria evaluada por el cirujano, el tiempo de recuperación y la satisfacción del paciente después de 24 horas. Para la evaluación se utilizaron el investigador ciego y puntajes compuestos. Resultados: Ambos grupos mostraron puntajes equivalentes en la hemodinamia intraoperatoria, en tanto que el BIE dio como resultado una mejor analgesia en el postoperatorio (p < 0.001). La opinión del cirujano y el tiempo de recuperación fueron comparables. En general, la experiencia de los pacientes fue satisfactoria con ambas técnicas, de acuerdo con la evaluación de calidad. Conclusiones: La infusión de dexmedetomidina IV es una alternativa efectiva al BIE para cirugías reconstructivas de hombro bajo anestesia general.

Abstract Introduction: Management of intraoperative hemodynamics and postoperative analgesia during arthroscopic shoulder surgeries remains a challenge. Although interscalene brachial plexus block (ISB) is considered ideal for shoulder anesthesia it requires skill and proficiency unlike intravenous (IV) dexmedetomidine. Objective: This randomized trial was performed to observe the efficacy of dexmedetomidine infusion which is less invasive and demands lesser skills than plexus block. Methodology: All patients scheduled for elective arthroscopic shoulder surgery under general anesthesia were assigned either to group DEX, which received an IV dexmedetomidine bolus of 0.5 mcg/kg over 20 minutes, followed by an infusion of 0.5 mcg/kg/hour that was stopped 30 minutes before surgery the end of surgery or to group BLOCK which received ultrasound guided ISB with 20ml of 0.25% bupivacaine. The primary outcome assessed was intraoperative hemodynamics; the secondary outcomes were immediate postoperative pain, operating condition as assessed by the surgeon, recovery time, and patient satisfaction after 24 hours. Blinded investigator and composite scores were used for the assessment. Results: Both groups displayed equivalent scores for intraoperative hemodynamics whereas ISB resulted in a better post-operative analgesia (p < 0.001). Surgeon's opinion and recovery time were comparable. Overall, the patients had a satisfactory experience with both techniques, according to the quality assessment. Conclusions: IV dexmedetomidine infusion is an effective alternative to ISB for reconstructive shoulder surgeries under general anesthesia.

Abstract The presented model for wideband circularly polarized microstrip antenna is an improved version of the previous models which is widely applicable to satellite, microwave relay and radar. The designed circularly polarized antenna having overall volume of 20× 20 × 1.6 mm3 actively works at the impedance bandwidth of 9000 MHz (4.0–12.9 GHz) having 105%(with 8900 MHz taken as center frequency). The 3-dB axial ratio bandwidth is obtained as 5500 MHz (5.4–10.9 GHz) depicting 67.5% (with 8150 MHz taken as the center frequency). Measured results of impedance bandwidth, axial ratio, gain and VSWR agrees to the simulation results.

ABSTRACT The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Wuhan, China, in December 2019 and quickly spread across the worldwide. It becomes a global pandemic and risk to the healthcare system of almost every nation around the world. In this study thirty natural compounds of 19 Indian herbal plants were used to analyze their binding with eight proteins associated with COVID -19. Based on the molecular docking as well as ADMET analysis, isovitexin, glycyrrhizin, sitosterol, and piperine were identified as potential herbal medicine candidates. On comparing the binding affinity with Ivermectin, we have found that the inhibition potentials of the Trigonella foenum-graecum (fenugreek), Glycyrrhiza glabra (licorice), Tinospora cordifolia (giloy) and Piper nigrum (black pepper) are very promising with no side-effects.

Abstract The state of Uttarakhand in India lies in a highly seismically active zone, therefore earthquake resistant design criteria have been followed for major construction practice in this region. One of the major inputs for earthquake-resistant design is average shear wave velocity (V S ) at 30 m depth. In the present work, at twenty-six different sites, the Horizontal to vertical spectral ratio (HVSR) technique and multichannel analysis of surface wave (MASW) is used for joint analysis to obtain a one-dimensional velocity model that supports both the HV spectrum and dispersion curve obtained from HVSR and MASW methods, respectively. Shear wave profiles obtained at various sites are compared with the bore log data obtained from drilling and it clearly shows that the (V S ) for the same formation have a strong dependence on the depth at which it occurred. Data from twenty-four shear wave profiles have been used to prepare a linear regression relation of (V S ) for different lithological formations with respect to their depth of occurrence. Root mean square error obtained from the developed relationship for various lithologies clearly shows that the results are fairly well within the range of acceptance. The developed relations have been further validated by calculating Vs profile from bore log data obtained at two new location sites that are not included in the data set used for the preparation of regression relations. A comparison of two velocity sections clearly shows that the velocity profile computed from regression relation matches closely with that obtained from the seismic survey and thereby establishing the efficacy of developed regression relationship for its practical implementation. This developed relation allows soil type classification for zoning purposes.

Resumen El estado de Uttarakhand en la India se encuentra en una zona de alta actividad sísmica, por lo que se han seguido criterios de diseño resistentes a los terremotos para las principales prácticas de construcción en esta región. Una de las principales entradas para el diseño resistente a los terremotos es la velocidad media de la onda de corte (V S ) a 30 m de profundidad. En el presente trabajo, en veintiséis sitios diferentes, la técnica de la relación espectral horizontal a vertical (HVSR) y el análisis multicanal de onda de superficie (MASW) se utiliza para el análisis conjunto para obtener un modelo de velocidad unidimensional que soporta tanto la curva de espectro de HV como la curva de dispersión obtenida de los métodos HVSR y MASW, respectivamente. Los perfiles de onda de corte obtenidos en varios sitios se comparan con los datos de registro de perforación obtenidos de la perforación y muestra claramente que los Vs para la misma formación tienen una fuerte dependencia de la profundidad en la que ocurrió. Se han utilizado datos de veinticuatro perfiles de onda de corte para preparar una relación de regresión lineal de Vs para diferentes formaciones litológicas con respecto a su profundidad de ocurrencia. El error cuadrático medio obtenido a partir de la relación desarrollada para varias litologías muestra claramente que los resultados están bastante bien dentro del rango de aceptación. Las relaciones desarrolladas han sido validadas adicionalmente por el cálculo de perfil Vs de los datos de registro de perforación obtenidos en dos nuevos sitios de ubicación que no están incluidos en el conjunto de datos utilizado para la preparación de relaciones de regresión. Una comparación de dos secciones de velocidad muestra claramente que el perfil de velocidad calculado a partir de la relación de regresión coincide estrechamente con el obtenido de la encuesta sísmica y por lo tanto se establece la eficacia de la relación de regresión desarrollada para su implementación práctica. Esta relación desarrollada permite la clasificación del tipo de suelo para fines de zonificación.

Abstract The ongoing coronavirus disease 2019 (COVID-19) has become a global pandemic and risk to the healthcare system of almost every nation around the world. The endocytic pathway has been considered as a key factor in viral infection. In the case of CoVs, several investigations have shown that these viruses mainly follow the clathrin-mediated endocytic pathway. As a result, inhibiting the clathrin-mediated endocytic pathway might be a useful therapeutic approach. In this study, bioactive components of Harsingar, Meethi neem, Tulsi and Ashwagandha extract was analyzed by HR-LCMS and among them 55 phytochemical compounds were selected based on antiviral and steroidal properties. 55 phytochemical compounds of four Indian herbal plants were used to analyze their binding with clathrin protein associated with COVID -19. Based on the molecular docking as well as ADMET analysis, Ashwagandha, Harsingar, Meethi neem and Tulsi were identified as potential herbal medicine candidates. We have found that the inhibition potentials of the Ashwagandha, Harsingar, Meethi neem and Tulsi are very promising with no side effects.

Resumen La enfermedad provocada por el coronavirus 2019 (COVID-19) se ha convertido en una pandemia global y pone en riesgo a los sistemas de salud de casi cualquier nación en el mundo. Se ha considerado que la ruta endocítica es un factor clave en la infección viral. En el caso de CoVs, varias investigaciones han mostrado que estos virus siguen la ruta endocítica mediada por la clatrina. Como resultado, inhibir la ruta endocítica mediada por la clatrina puede ser una propuesta terapéutica útil. En este estudio, se analizaron extractos de componentes bioactivos de Harsingar, Meethi neem, Tulsi y Ashwagandha por HR-LCMS y entre ellos se seleccionaron 55 compuestos fitoquímicos basados en sus propiedades antivirales y esteroidales. Estos 55 compuestos obtenidos de 4 plantas herbáceas se utilizaron para analizar su interacción con la proteína clatrina asociada al COVID-19. Basados en el acoplamiento molecular, así como en el análisis ADMET, se determinó que Harsingar, Meethi neem, Tulsi y Ashwagandha son candidatos potenciales de medicinas herbáceas. Hemos encontrado que los potenciales de inhibición de Harsingar, Meethi neem, Tulsi y Ashwagandha son muy promisorios y no muestran efectos colaterales.

Intraductal papillary neoplasm of the bile duct (IPN-B) is a rare preinvasive intraductal pathology of the biliary tract. It should be differentiated from other more common benign or malignant causes of biliary obstruction and dilatation such as calculi or cholangiocarcinoma because the management and prognosis of this condition differs significantly. This case report describes a case of IPN-B in a 45-year-old female patient who presented with non-specific complaints of chronic abdominal pain without jaundice for three months.

Abstract G × E interaction is major cause of discrepancy in crop yield under different environments. International Rice Research Institute (IRRI) launched their fourth flagship project on Global Rice Array (GRA-IV) to identify climate resilient rice genotypes. The G x E interaction was studied in ‘Antenna Panel’ genotypes Of rice using AMMI model. The results indicated that main effects as well as interactive G x E effects were significant for most of the traits. Major portion of the G x E was contributed by the genotypes. AMMI model having two principle components axis was found as the best predictive model. On the basis of biplots and ASV score SAHEL 177 for days to 50% flowering, SADRI for plant height; FEDEARROZ 50 for panicle length; CT11891-2-2-7-M for number of grains panicle-1 and SAHEL 108 for grain yield were considered as most stable genotypes in all the consecutive three environments. Moreover Yield Stability Index (YSI) supported the results that SAHEL 108 is the most superior genotype for grain yield over all the three environments of testing. Findings from this study are expected to help breeders to select suitable genotype on the basis of its performance and stability over locations. which can provide a head start to the rice improvement programmes for Indo-gangetic Plains and Hilly Tarai regions of India.

Resumo O pseudoaneurisma de artéria esplênica é o mais comum entre os pseudoaneurismas de artérias viscerais. A apresentação geralmente varia e requer diagnóstico e tratamento imediatos, pois a ruptura do pseudoaneurisma aumenta a morbimortalidade. Esse tipo de pseudoaneurisma está associado à pancreatite e a outras condições, como trauma abdominal, pancreatite crônica, pseudocisto de pâncreas, transplante de fígado e, raramente, úlcera péptica. Apresentamos um caso de pseudoaneurisma gigante de artéria esplênica, com tamanho de 14x8 cm. Durante o procedimento, não foi possível alcançar controle proximal e distal dos vasos devido a aderências locais e inflamação, sendo necessário o clampeamento da aorta supracelíaca para controle do sangramento.

Abstract Splenic artery pseudoaneurysm is the most common of all the visceral artery pseudoaneurysms. Presentation is often variable and the condition demands immediate diagnosis and management because pseudoaneurysm rupture increases morbidity and mortality. It is associated with pancreatitis and other conditions like abdominal trauma, chronic pancreatitis, pseudocyst of the pancreas, liver transplantation, and, rarely, peptic ulcer disease. We present a case of a giant splenic artery pseudoaneurysm measuring 14x8 cm. Proximal and distal control of the vessels could not be achieved during the procedure because of local adhesions and inflammation and it was necessary to cross clamp the supraceliac aorta to control bleeding.

Resumo Na medida em que um número crescente de governos nacionais tem promovido políticas econômicas nacionalistas e o rompimento ou a renegociação de relações políticas e econômicas globais, a impossibilidade de desconexão de circulações globais é ilustrada pela própria difusão do discurso do nacionalismo econômico, embora concebido e implementado diferentemente, em resposta a contextos históricos e políticos específicos. Com base nas possibilidades das antropologias mundiais, os autores constroem análises conectadas dos efeitos vividos e das contradições das políticas econômicas nacionalistas, por meio de exemplos etnográficos do Brasil, da Índia, de Uganda e dos Estados Unidos. Analisando esses contextos comparativamente, o artigo enfatiza a natureza plural, transhistórica, transnacional, generificada e contestada das políticas e discursos nacionalistas econômicos no mundo, apontando para a necessidade do aprofundamento de pesquisas empíricas sobre os diversos sentidos e mobilizações políticas de projetos nacionalistas econômicos.

Abstract As rising numbers of national governments promote economic nationalist policies and the withdrawal from (or renegotiation of) global political and economic relationships, the impossibility of disconnecting from global circulations is illustrated by the traveling discourse of economic nationalism itself, although conceptualized and implemented quite differently as refracted through specific historical and political contexts. Drawing on the possibilities of world anthropologies, the authors build connected analyses of the lived effects and contradictions of economic nationalist policies through their ethnographic examples from Brazil, India, Uganda, and the US. In comparatively analyzing these contexts, the authors emphasize the plural, transhistorical, transnational, gendered, and contested nature of economic nationalist policies and discourses worldwide, pointing to the need for further empirical investigations into diverse understandings and political deployments of economic nationalist projects.

Abstract The usage of wheeled robots in service robots such as planetary exploration robots, pick-and- place robots, cleaning robots, surveillance robots, etc., is continuously increasing day by day. The primary purpose of these service robots is to reduce human resources and minimize life risk of human in a hazardous environment. Therefore, in this article, the authors propose and design the all-terrain differential-driven caterpillar-wheeled based unmanned Fire Extinguisher Robot (FER), which can detect and monitor fire by using a gas (smoke) sensor and temperature sensor. Also, it can extinguish the fire by spreading the fire extinguisher gas. The proposed unmanned FER has been divided into two assembled units, one unit drives the FER, and the other is for spreading the fire extinguisher gas through the nozzle of the cylinder. The driving unit of unmanned FER consists of six DC geared motors, two dual DC motor drivers, caterpillar driving wheels, Arduino MEGA microcontroller, Bluetooth module, gas sensor, temperature sensor, and rechargeable lithium-polymer (LiPo) battery. Besides, one DC motor connected with a motor driver controls the fire extinguisher gas cylinder's opening and closure valve through a Bluetooth signal from an android phone. The specially designed chassis and caterpillar driving wheel arrangement help the FER to travel in any terrain, including stair climbing. Furthermore, the other advantage of this unmanned FER is that it can extinguish the fire from a distance of more than 200 cm by spreading the fire extinguisher gas through the nozzle of the cylinder. Real-time experimental tests have been carried out on the designed unmanned FER during the fire extinguishing process to prove the effectiveness of the developed FER.