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Abstract Introduction: recent studies have suggested the use of neck circumference as a parameter capable of identifying risks of cardiometabolic complications and the accumulation of truncal fat caused by both antiretroviral therapy and the lifestyle of people with the human immunodeficiency virus (HIV). Objective: to investigate the relationship between neck circumference and anthropometric indicators and to assess cardiometabolic risk and truncal obesity through proposed cut-off points. Methods: cross-sectional study including 233 people with HIV. Demographic, socioeconomic, lifestyle and clinical data were collected using a structured questionnaire. The anthropometric evaluation included: weight, height, body mass index (BMI) measurements; waist (WC), neck (NC), arm and arm muscle circumferences; triceps and subscapular skinfolds and their sum. ROC curves were constructed to determine the accuracy of NC in predicting cardiometabolic risk in people living with HIV. Results: the sample was 57.5 % male, with a mean age of 38.4 years (95 % CI: 37.2-39.7 years). NC showed a positive and significant correlation with all anthropometric variables analyzed (p < 0.05), and a higher correlation strength with WC and BMI. The NC cut-off point selected as a predictor of risk of cardiac metabolic complications and truncal obesity in women was ≥ 32.4 cm, considering both WC and BMI. For men, the NC cut-off points were different when considering WC (≥ 39.6 cm) and BMI (≥ 38.1 cm) as a reference. It is worth noting that NC performed well in ROC curve analysis for men, while in women it was a poor performance. Conclusion: NC proved to be a promising indicator in the assessment of nutrition and health of people living with HIV, especially in men.

Resumen Introducción: estudios recientes han sugerido el uso de la circunferencia del cuello como parámetro capaz de identificar los riesgos de complicaciones cardiometabólicas y la acumulación de grasa troncal causados tanto por la terapia antirretroviral como por el estilo de vida de las personas con el virus de la inmunodeficiencia humana (VIH). Objetivo: investigar la relación entre la circunferencia del cuello y los indicadores antropométricos y evaluar el riesgo cardiometabólico y la obesidad troncal a través de los puntos de corte propuestos. Métodos: estudio transversal que incluyó a 233 personas con VIH. Se recogieron datos demográficos, socioeconómicos, de estilo de vida y clínicos mediante un cuestionario estructurado. La evaluación antropométrica incluyó: medidas de peso, altura, índice de masa corporal (IMC); circunferencias de cintura (CC), cuello (CN), brazo (CA) y músculo del brazo (MCB); pliegues cutáneos del tríceps y subescapular y su suma. Se construyeron curvas ROC para determinar la precisión de la CN en la predicción del riesgo cardiometabólico en personas que viven con el VIH. Resultados: el 57,5 % de la muestra eran varones, con una edad media de 38,4 años (IC 95 %: 37,2-39,7 años). La CN mostró una correlación positiva y significativa (p < 0,05) con todas las variables antropométricas analizadas, y una mayor fuerza de correlación con la CC y el IMC. El punto de corte de la CN seleccionado como predictor de riesgo de complicaciones metabólicas cardiacas y obesidad troncular en mujeres fue ≥ 32,4 cm, considerando tanto la CC como el IMC. En el caso de los hombres, los puntos de corte de la CN fueron diferentes al considerar como referencia la CC (≥ 39,6 cm) y el IMC (≥ 38,1 cm). Cabe destacar que la CN obtuvo buenos resultados en el análisis de la curva ROC en el caso de los hombres, mientras que en el de las mujeres fue deficiente. Conclusión: la CN demostró ser un indicador prometedor en la evaluación de la nutrición y la salud de las personas que viven con el VIH, especialmente en los hombres.

https://doi.org/10.20960/nh.04402

The effect of Vitamin E supplementation on inflammatory biomarkers and oxidative stress in patients with chronic kidney disease on hemodialysis: A systematic review
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Morais de Sousa, Dallyla Jennifer

; Cardoso de Sousa, Larissa Layana

; Oliveira Barrense, Clenio

; Cardoso de Araújo, Diana Stefany

; Visgueira de Sousa, Thayanne Gabryelle

; de Azevedo Paiva, Adriana

; Silva de Almendra Freitas, Betânia de Jesus e

Revista chilena de nutrición

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feb 2023, Volume 50 N. 1 Pages 117 - 126

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN La hemodiálisis, junto con la enfermedad renal crónica (ERC), intensifica el proceso inflamatorio y el estrés oxidativo en los pacientes en tratamiento. En este contexto, la suplementación con vitamina E puede mitigar los efectos nocivos resultantes de estos procesos. Esta es una revisión sistemática cuyo objetivo fue evaluar el efecto de la suplementación con vitamina E sobre biomarcadores inflamatorios y estrés oxidativo en pacientes con ERC en hemodiálisis. La revisión se elaboró según la metodología para revisiones sistemáticas y metanálisis (PRISMA) y la búsqueda se realizó en las bases de datos Pubmed, Cochrane Library, Scopus y Web of Science. El riesgo de sesgo de los estudios incluidos se evaluó con la Herramienta Cochrane de Riesgo de Sesgo (Cochrane Risk of Bias Tool). En esta revisión se incluyeron doce estudios desarrollados entre 2006 y 2020. La mayoría (n= 11) utilizó dosis de vitamina E que oscilaban entre 400 UI y 888 UI y el tiempo de suplementación osciló entre 2 semanas y 12 meses. De los 12 artículos incluidos, 25% (n= 3) analizaba la suplementación en biomarcadores inflamatorios, 50% (n= 6) en biomarcadores de estrés oxidativo y 25% (n= 3) en estos parámetros simultáneamente. Se observó un efecto positivo en 58,4% de los estudios (n= 7). Por lo tanto, la suplementación con vitamina E puede ser efectiva para mitigar el proceso inflamatorio y el estrés oxidativo, sin embargo, vale la pena señalar que el efecto depende de la dosis y el tiempo de suplementación.

ABSTRACT Hemodialysis, along with chronic kidney disease (CKD), intensifies the inflammatory process and oxidative stress in patients undergoing treatment. In this context, Vitamin E supplementation can mitigate the deleterious effects resulting from these processes. This is a systematic review whose objective was to evaluate the effect of Vitamin E supplementation on inflammatory biomarkers and oxidative stress in patients with CKD on hemodialysis. This review was prepared according to the methodology for systematic reviews and meta-analyses (PRISMA) and the search was performed in Pubmed, Cochrane Library, Scopus and Web of Science databases. The risk of bias of the included studies was assessed with the Cochrane Risk of Bias Tool. Twelve studies developed between 2006 and 2020 were included in this review. Most of them (n= 11) used vitamin E doses ranging from 400 IU to 888 IU and the supplementation time ranged from 2 weeks to 12 months. Of all the 12 articles included, 25% (n= 3) analyzed supplementation on biomarkers of oxidative stress and 25% (n= 3) addressed these parameters simultaneously. A positive effect was observed in 58.4% of the studies (n= 7). Thus, Vitamin E supplementation can be effective in mitigating the inflammatory process and oxidative stress, however, it is worth noting that the effect depends on the dose and time of supplementation.

Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force
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Tavares, Anna Carolina Faria Moreira Gomes

; Melo, Ana Karla Guedes de

; Cruz, Vítor Alves

; Souza, Viviane Angelina de

; Carvalho, Joana Starling de

; Machado, Ketty Lysie Libardi Lira

; Valadares, Lilian David de Azevedo

; Reis Neto, Edgard Torres dos

; Rezende, Rodrigo Poubel Vieira de

; Guimarães, Maria Fernanda Brandão de Resende

; Ferreira, Gilda Aparecida

; Braz, Alessandra de Sousa

; Vieira, Rejane Maria Rodrigues de Abreu

; Pinheiro, Marcelo de Medeiros

; Ribeiro, Sandra Lúcia Euzébio

; Bica, Blanca Elena Gomes Rios

; Baptista, Kátia Lino

; Costa, Izaias Pereira da

; Marques, Claudia Diniz Lopes

; Lopes, Maria Lúcia Lemos

; Martinez, José Eduardo

; Giorgi, Rina Dalva Neubarth

; Mota, Lícia Maria Henrique da

; Loures, Marcos Antônio Araújo da Rocha

; Paiva, Eduardo dos Santos

; Monticielo, Odirlei André

; Xavier, Ricardo Machado

; Kakehasi, Adriana Maria

; Pileggi, Gecilmara Cristina Salviato

Advances in Rheumatology

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2022, Volume 62 elocation 3

Abstract: En | Text: En | PDF: En

Abstract Objective: To provide guidelines on the coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated rheumatic diseases (IMRD) to rheumatologists considering specific scenarios of the daily practice based on the shared-making decision (SMD) process. Methods: A task force was constituted by 24 rheumatologists (panel members), with clinical and research expertise in immunizations and infectious diseases in immunocompromised patients, endorsed by the Brazilian Society of Rheumatology (BSR), to develop guidelines for COVID-19 vaccination in patients with IMRD. A consensus was built through the Delphi method and involved four rounds of anonymous voting, where five options were used to determine the level of agreement (LOA), based on the Likert Scale: (1) strongly disagree; (2) disagree, (3) neither agree nor disagree (neutral); (4) agree; and (5) strongly agree. Nineteen questions were addressed and discussed via teleconference to formulate the answers. In order to identify the relevant data on COVID-19 vaccines, a search with standardized descriptors and synonyms was performed on September 10th, 2021, of the MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and LILACS to identify studies of interest. We used the Newcastle–Ottawa Scale to assess the quality of nonrandomized studies. Results: All the nineteen questions-answers (Q&A) were approved by the BSR Task Force with more than 80% of panelists voting options 4—agree—and 5—strongly agree—, and a consensus was reached. These Guidelines were focused in SMD on the most appropriate timing for IMRD patients to get vaccinated to reach the adequate covid-19 vaccination response. Conclusion: These guidelines were developed by a BSR Task Force with a high LOA among panelists, based on the literature review of published studies and expert opinion for COVID-19 vaccination in IMRD patients. Noteworthy, in the pandemic period, up to the time of the review and the consensus process for this document, high-quality evidence was scarce. Thus, it is not a substitute for clinical judgment.

https://doi.org/10.1186/s42358-022-00234-7

Prevalence of prediabetes in adults and its association with sociodemographic, nutritional, metabolic and mental disorders factors: Home Health Survey, Piauí, Brazil.
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LIMA, Carlos Henrique Ribeiro

; DA PAZ, Suzana Maria Rebêlo Sampaio

; LAVÔR, Layanne Cristina de Carvalho

; FROTA, Karoline de Macêdo Gonçalves

; PAIVA, Adriana de Azevedo

Revista de Nutrição

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2022, Volume 35 elocation e220046

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Estimar a prevalência de pré-diabetes e investigar os fatores associados em adultos residentes em Teresina, Piauí, Brasil. Métodos Estudo transversal de base domiciliar com adultos de ambos os sexos em Teresina, Piauí. A prevalência de pré-diabetes foi estimada pelo teste de glicemia em jejum, e classificado de acordo com a Associação Americana de Diabetes (≥100mg/dL; <126mg/dL). Foram testadas as associações entre pré-diabetes e as variáveis: sociodemográficas, antropométricas, consumo alimentar, níveis pressóricos, triglicerídeos e transtornos mentais comuns. Além disso, foi criada uma variável para verificar a associação da presença simultânea dos fatores de risco no mesmo indivíduo. Os dados foram analisados com o teste do qui-quadrado de Pearson e regressão de Poisson para razões de prevalência bruta e ajustada, considerando nível de significância de 5%. Resultados Participaram do estudo 224 adultos, sendo 154 (68,7%) do sexo feminino, entre 20 e 39 anos (53,1%). Verificou-se prevalência de pré-diabetes de 8,04%, com associação significativa (p<0,05) com a menor escolaridade (17,3%), e triglicerídeos elevados (13,7%). Observou-se maior razão de prevalência bruta (RP: 2,53; IC 95%: 1,05-6,05) de pré-diabetes nos indivíduos com 5 ou mais fatores de risco simultâneos quando comparados àqueles com até 4 fatores simultâneos. Conclusão A baixa escolaridade, a hipertrigliceridemia e a presença de cinco ou mais fatores de risco simultâneos apresentaram-se associados ao pré-diabetes. Entretanto, os fatores de risco encontrados são passíveis de intervenção. Este estudo aponta a necessidade de mudanças de hábitos de vida comportamentais como estratégia para o controle da glicemia e prevenção do diabetes.

ABSTRACT Objective To estimate prevalence of prediabetes and to investigate its associated factors in adults living in Teresina, Piauí, Brazil Methods Cross-sectional, home-based study, with both genders adults in Teresina, Piauí. The prevalence of prediabetes was estimated using the fasting glucose test, and was classified according to the American Diabetes Association standards (≥100mg/dL; <126mg/dL). The associations between prediabetes and the variables: sociodemographic, anthropometric, food consumption, blood pressure levels, triglycerides and common mental disorders were tested. In addition, a variable was created to verify the association of the simultaneous presence of risk factors in the same individual. Data were reviewed using Pearson’s chi-square test and Poisson regression for crude and adjusted prevalence ratios, considering a significance level of 5%. Results A total of 224 adults participated in the study, of which 154 (68.7%) were female, aged between 20 and 39 years (53.1%). An 8.04% prevalence of prediabetes was observed. A statistically significant association (p<0.05) was found between lower education (0 to 8 years of study; 17.3%) and increased triglycerides levels (≥150mg/dL; 13.7%). Higher gross prevalence (PR: 2.53; CI 95%: 1.05-6.05) prediabetes ratios were observed with 5 or more simultaneous risk factors when compared to individuals who had up to 4 simultaneous risk factors. Conclusion Low schooling, hypertriglyceridemia and the presence of five or more simultaneous risk factors were associated with prediabetes; however, these risk factors are subject to intervention. Therefore, this study points to the need for changes in lifestyle habits as a strategy for glycemic control and diabetes prevention.

https://doi.org/10.1590/1678-9865202235e220046

Effects of vitamin D supplementation on the glycemic control of pre-diabetic individuals: a systematic review
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Lima, Carlos Henrique Ribeiro

; Lavôr, Layanne Cristina de Carvalho

; Nogueira, Nadir do Nascimento

; Rodrigues, Gilmara Péres

; Frota, Karoline de Macedo Gonçalves

; Teixeira, Nayra do Socorro Caldas Carvalho de Almeida

; Oliveira, Iara Katrynne Fonsêca

; Paiva, Adriana de Azevedo

Nutrición Hospitalaria

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feb 2021, Volume 38 N. 1 Pages 186 - 193

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Introduction: research shows the potential effect of vitamin D supplementation with an improvement in the glycemic profile of pre-diabetic patients. Objective: this study evaluates the effects of vitamin D supplementation on glycemic control markers in pre-diabetic individuals. Methods: we analyzed studies published over the last ten years, and indexed in the Science Direct, PubMed, and LILACS databases. We searched studies using health descriptors related to vitamin D, pre-diabetes, and glycemic control markers. We considered randomized controlled trials eligible for inclusion. All phases of selection, data extraction, and risk of bias assessment were carried out by two independent evaluators. Results: we identified 309 articles, of which 4 met the inclusion criteria. Of these, 3 studies have shown that vitamin D supplementation does not alter glycemic control markers in pre-diabetic individuals. Only one study showed a positive effect after supplementation with 60,000 IU/month of vitamin D3 for 12 months, with a significant reduction in the concentrations of glycated hemoglobin, fasting glucose, and two-hour postprandial glucose. Conclusion: there is insufficient scientific evidence to confirm the beneficial effects of vitamin D supplementation on glycemic control markers in pre-diabetic individuals.

Resumen Introducción: las investigaciones muestran el efecto potencial de la suplementación con vitamina D con una mejora del perfil glucémico de los pacientes prediabéticos. Objetivo: este estudio evalúa los efectos de la suplementación con vitamina D sobre los marcadores de control glucémico en personas prediabéticas. Métodos: analizamos los estudios publicados en los últimos diez años e indexados en las bases de datos Science Direct, PubMed y LILACS. Se realizaron búsquedas de estudios mediante descriptores de salud relacionados con la vitamina D, la prediabetes y los marcadores de control glucémico. Los ensayos controlados y aleatorizados se consideraron elegibles para su inclusión. Todas las fases de selección, extracción de datos y evaluación del riesgo de sesgos fueron realizadas por dos evaluadores independientes. Resultados: identificamos 309 artículos, de los que 4 cumplieron los criterios de inclusión. De estos, 3 estudios demostraron que la suplementación con vitamina D no altera los marcadores de control glucémico en las personas prediabéticas. Solo un estudio mostró un efecto positivo después de la suplementación de 60.000 UI/mes de vitamina D3 durante 12 meses, con una reducción significativa de las concentraciones de hemoglobina glucosilada, glucosa en ayunas y glucosa posprandial a las dos horas. Conclusión: no hay evidencia científica suficiente para confirmar los efectos beneficiosos de la suplementación de vitamina D sobre los marcadores de control glucémico en las personas prediabéticas.

https://doi.org/10.20960/nh.03309

Nutritional status and vitamin A and zinc levels in patients with kala-azar in Piauí, Brazil
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Monteiro, Mísia Joyner de Sousa Dias

; Silva, Maria Nauside Pessoa da

; Paiva, Adriana de Azevedo

; Marreiro, Dilina do Nascimento

; Luzia, Liania Alves

; Henriques, Gilberto Simeone

; Rondó, Patrícia Helen de Carvalho

; Sene, Ingridi de Souza

; Almeida, Ana Tárcila Alves de

; Costa, Carlos Henrique Nery

; Costa, Dorcas Lamounier

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e0800-2020

Abstract: En | Text: En | PDF: En

Abstract INTRODUCTION: Malnutrition and kala-azar (or visceral leishmaniasis) are significant public health problems in different parts of the world. Immunity and susceptibility to infectious and parasitic diseases are directly linked to the host’s nutritional state, but little is known about the interaction between nutrition and kala-azar. This study aimed to evaluate nutritional status with kala-azar and correlate these findings with the clinical and laboratory manifestations of the disease, and zinc and retinol levels. METHODS: This was a cross-sectional study of 139 patients with kala-azar. Nutritional status classification was performed according to international recommendations. Parametric or nonparametric tests were applied whenever indicated in a two-sided test with a 5% significance level. RESULTS: Weight loss and malnutrition were more frequent in adults. Body mass index-for-age, fat area of the arm, and upper arm muscle area were significantly associated with probability of death. The presence of human immunodeficiency virus, hepatomegaly, and splenomegaly was correlated with nutritional assessment. Blood leukocyte and lymphocyte, serum creatine, and vitamin A levels were significantly higher in adult men. Vitamin A levels were highly associated with the level of hemoglobin and C-reactive protein (CRP) in multivariate analysis. All patients had reduced plasma zinc levels, but this finding had no association with the outcome variables. CONCLUSIONS: Malnutrition was correlated with severe disease and was more prevalent in older people with kala-azar. Vitamin A deficiency was associated with hemoglobin and CRP. Zinc levels were reduced in patients with kala-azar.

https://doi.org/10.1590/0037-8682-0800-2020 77 downloads

Sampling plan and methodological aspects: a household healthcare survey in Piauí
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Rodrigues, Lays Arnaud Rosal Lopes

; Costa e Silva, Danilla Michelle

; Oliveira, Edina Araújo Rodrigues

; Lavôr, Layanne Cristina de Carvalho

; Sousa, Rosana Rodrigues de

; Carvalho, Rumão Batista Nunes de

; Farias Junior, Gilvo de

; Formiga, Laura Maria Feitosa

; Sousa, Artemizia Francisca de

; Cardoso, Maria Regina Alves

; Slater, Betzabeth

; Conde, Wolney Lisbôa

; Paiva, Adriana de Azevedo

; Frota, Karoline de Macêdo Gonçalves

Revista de Saúde Pública

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2021, Volume 55 elocation 118

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT OBJECTIVE To describe the methodological aspects of the Piauí home healthcare survey (ISAD-PI) and assess the relation between sampling plan, precision, and design effects, assuming that population health surveys are relevant instruments for health monitoring. METHODS ISAD-PI was a population-based cross-sectional study that analyzed the living conditions and health status of the population residing in urban areas in the municipalities of Teresina and Picos, in Piauí. Sampling was carried out by conglomerates in two stages: Primary Sampling Units and households. To calculate the sample size, we considered the stratification of the population in both cities, according to the age of the individuals. We evaluated the “non-response” rate (NRR) and estimated the proportions according to sex and age, as well as the prevalence of social determinants of health in order to assess the compliance of the sampling plan. Analyses related to the precision according to the coefficient of proportion variation of the standard error (Cv-pˆ) and the design effect (deff). Cv-pˆ less than 20% and deff less than 1.5 were considered adequate. The total NRR of households was 38.2% in Teresina and 38.3% in Picos. We carried out twenty-four proportion estimates in relation to age and sex and 48 prevalence of social and health determinants estimates, totaling 72 estimates. Among them, 71 had Cv-pˆ less than 20% and 61 had deff less than or equal to 1.5. CONCLUSION Data generated from the ISAD-PI may contribute to the assessment of health and morbidity conditions in the population. Furthermore, methodological aspects employed in this research may serve as a basis for studies carried out in other cities in Brazil.

RESUMO OBJETIVO Descrever os aspectos metodológicos do Inquérito de Saúde Domiciliar no Piauí (ISAD-PI), bem como avaliar a conformidade do plano amostral em relação à precisão e aos efeitos do desenho, dado que os inquéritos populacionais de saúde constituem instrumentos importantes para o monitoramento da situação de saúde da população. MÉTODOS O ISAD-PI foi um estudo de base populacional, transversal, que analisou as condições de vida e situação de saúde da população residente nas áreas urbanas dos municípios de Teresina e Picos, no Piauí. A amostragem foi realizada por conglomerados, em dois estágios: Unidades Primárias de Amostragem e domicílios. Para o cálculo do tamanho da amostra, considerou-se a estratificação da população de ambas as cidades, de acordo com a idade dos indivíduos, para ambos os sexos. Para avaliação da conformidade do plano amostral, foi avaliada a taxa de “não-resposta” (TNR) e, além disso, as estimativas de proporções segundo sexo e idade, bem como as prevalências de determinantes sociais de saúde, que foram analisadas em relação à precisão por meio do coeficiente de variação da proporção do erro padrão (Cv-pˆ) e do efeito do delineamento (deff). Foram considerados adequados Cv-pˆ menores que 20%, e deff menores que 1,5. A TNR-Total dos domicílios foi de 38,2% em Teresina e de 38,3% em Picos. Foram realizadas 24 estimativas de proporção em relação à idade e ao sexo e 48 estimativas de prevalência de determinantes sociais e de saúde, totalizando 72 estimativas, das quais 71 apresentaram Cv-pˆ menor que 20% e 61 apresentaram deff menor ou igual a 1,5. CONCLUSÃO Dados gerados a partir do ISAD-PI poderão contribuir para a avaliação das condições de saúde e morbidade na população. Ademais, aspectos metodológicos empregados nesta pesquisa poderão servir de base para estudos realizados em outras cidades do Brasil.

https://doi.org/10.11606/s1518-8787.2021055003441

Sampling plan and methodological aspects: a household healthcare survey in Piauí
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Rodrigues, Lays Arnaud Rosal Lopes

; Costa e Silva, Danilla Michelle

; Oliveira, Edina Araújo Rodrigues

; Lavôr, Layanne Cristina de Carvalho

; Sousa, Rosana Rodrigues de

; Carvalho, Rumão Batista Nunes de

; Farias Junior, Gilvo de

; Formiga, Laura Maria Feitosa

; Sousa, Artemizia Francisca de

; Cardoso, Maria Regina Alves

; Slater, Betzabeth

; Conde, Wolney Lisbôa

; Paiva, Adriana de Azevedo

; Frota, Karoline de Macêdo Gonçalves

Revista de Saúde Pública

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2021, Volume 55 elocation 118

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.11606/s1518-8787.2021055003441

Prevalence of arterial hypertension and associated factors: a population-based study
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Lavôr, Layanne Cristina de Carvalho

; Sousa, Rosana Rodrigues de

; Rodrigues, Lays Arnaud Rosal Lopes

; Rodrigues Filho, Onias de Sousa

; Paiva, Adriana de Azevedo

; Frota, Karoline de Macêdo Gonçalves

Revista da Associação Médica Brasileira

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may 2020, Volume 66 N. 5 Pages 630 - 636

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Estimar a prevalência de hipertensão arterial em adultos e analisar sua associação com fatores de risco socioeconômicos, demográficos e de estilo de vida. MÉTODOS Estudo epidemiológico transversal, de base domiciliar, realizado com adultos de ambos os sexos residentes nas cidades de Teresina e Picos (PI). A prevalência de hipertensão arterial foi estimada por meio de diagnóstico autorreferido. Foram testadas as associações entre a hipertensão arterial e as variáveis: idade, sexo, cor da pele, escolaridade, renda familiar, situação conjugal, consumo de álcool e cigarro, prática de atividade física e estado nutricional. RESULTADOS Participaram do estudo 1.057 indivíduos adultos com média de idade de 38,6 ± 11,5 anos, sendo 62,3% do sexo feminino. A prevalência de hipertensão arterial na população foi de 16,4%. Na análise bruta, observou-se associação significativa entre a prevalência de hipertensão e fatores como maior idade, menor escolaridade, estado civil solteiro, cor da pele parda, tabagismo e excesso de peso (p<0,05). Entretanto, após ajustes, apenas as associações com a maior idade, cor da pele parda, estilo de vida sedentário e excesso de peso mantiveram-se significativas. CONCLUSÃO A idade mais avançada, cor da pele parda, sedentarismo e a presença de sobrepeso ou obesidade apresentaram-se significativamente associados à hipertensão. Dentre os fatores de risco modificáveis, destaca-se o sedentarismo e o excesso de peso como importantes para a gênese de hipertensão e passíveis de medidas de intervenção.

SUMMARY OBJECTIVE To estimate the prevalence of hypertension in adults and analyze its association with socioeconomic, demographic, and lifestyle risk factors. METHODS Home-based cross-sectional epidemiological study conducted with adults of both sexes living in the cities of Teresina and Picos (PI). The prevalence of hypertension was estimated by self-reported diagnosis. The associations between hypertension and the following variables were tested: age, gender, skin color, education, family income, marital status, alcohol and cigarette consumption, physical activity, and nutritional status. RESULTS A total of 1,057 adult individuals with a mean age of 38.6 ± 11.5 years participated in the study, of which 62.3% were female. The prevalence of hypertension in the population was 16.4%. In the crude analysis, a significant association was observed between the prevalence of hypertension and factors such as older age, lower education, single marital status, brown skin color, smoking, and overweight (p < 0.05). However, after adjustments, only the associations with older age, brown skin color, sedentary lifestyle and overweight remained significant. CONCLUSION Older age, brown skin color, sedentary lifestyle, and the presence of overweight or obesity were significantly associated with hypertension. Among the modifiable risk factors, a sedentary lifestyle and overweight stand out as important for the genesis of hypertension, subject to intervention measures.

https://doi.org/10.1590/1806-9282.66.5.630 1169 downloads

10.

Impact of intermittent fasting on body weight in overweight and obese individuals
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Lima, Carlos Henrique Ribeiro

; Oliveira, Iara Katrynne Fonsêca

; Frota, Karoline de Macêdo Gonçalves

; Carvalho, Cecilia Maria Resende Gonçalves de

; Paiva, Adriana de Azevedo

; Campelo, Viriato

; Martins, Maria do Carmo de Carvalho e

Revista da Associação Médica Brasileira

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feb 2020, Volume 66 N. 2 Pages 222 - 226

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO OBJETIVO Verificar a relação do jejum intermitente no peso corporal de indivíduos com sobrepeso e obesidade por meio de uma revisão sistemática da literatura. MÉTODOS Trata-se de uma revisão sistemática, baseada em ensaios clínicos randomizados. Os artigos foram consultados nas bases de dados: Science Direct, PubMed e BVS. A avaliação dessa revisão ocorreu por meio da recomendação Prisma. RESULTADOS Após o processo de seleção, quatro artigos foram incluídos nesta revisão, comparando o jejum intermitente (JI) com dieta de restrição calórica (DRC) como grupo controle. Em dois estudos com utilização de protocolos semelhantes não houve redução significativa no peso corporal dos indivíduos com sobrepeso ou obesidade. Já nos outros dois estudos com utilização de protocolos distintos, a perda de peso foi significativa no grupo JI em comparação ao grupo DRC. CONCLUSÕES Os achados desta revisão não fornecem evidências plausíveis do efeito do jejum intermitente na perda de peso em indivíduos com sobrepeso ou obesidade.

SUMMARY OBJECTIVE To verify the relationship of intermittent fasting in the bodyweight of overweight and obese individuals through a systematic literature review. METHODS This is a systematic review based on randomized controlled trials. The articles were consulted in the databases: Science Direct, PubMed e BVS. This review was evaluated through the PRISMA recommendation. RESULTS After the selection process, four articles were included in this review, comparing intermittent fasting (IF) with calorie restriction diet (CRD) as a control group. In 2 studies using similar protocols, there was no significant reduction in body weight of overweight or obese subjects. In the other two studies using different protocols, weight loss was significant in the IF group compared to the CRD group. CONCLUSIONS Results did not provide evidence of the effect of intermittent fasting on weight loss in overweight or obese individuals.

https://doi.org/10.1590/1806-9282.66.2.222 6649 downloads

11.

An approach on food choice determinants: a study in the restaurants of a public market in Northeastern Brazil
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MOURA, Ana Claudia Carvalho

; MELO, Martha Teresa Siqueira Marques

; SILVA, Bianca Lourrany dos Santos

; PAZ, Suzana Maria Rebêlo Sampaio da

; PAIVA, Adriana de Azevedo

; CARVALHO, Cecilia Maria Resende Gonçalves de

Revista de Nutrição

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2020, Volume 33 elocation e190126

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Identificar os principais determinantes do consumo alimentar entre adultos usuários de um mercado público de uma capital do nordeste brasileiro. Métodos Foram entrevistados, por intermédio de questionários pré-testados, nos meses de agosto de 2018 até janeiro de 2019, uma amostra de 198 comensais de um mercado público, constituída por 149 indivíduos do sexo masculino e 49 do sexo feminino maiores de 19 anos. Foram avaliadas variáveis sociodemográficas como sexo, idade, local de origem, escolaridade e renda, além dos determinantes das escolhas alimentares. A análise foi feita utilizando o teste de Wilcoxon (não paramétrico), que comparou as médias das dimensões envolvidas nessas escolhas conforme sexo e renda. Resultados Apelo sensorial, preço e saúde foram os principais determinantes das escolhas alimentares. Quando comparados por sexo e renda, houve diferenças significativas quanto aos atributos analisados. Conclusão Os fatores que influenciaram a escolha alimentar foram: apelo sensorial, preço e saúde. Já as questões éticas foram as que menos interferiram na escolha alimentar. Desse modo, tais aspectos devem ser levados em consideração para o desenvolvimento de políticas públicas na área de alimentação coletiva e educação ambiental.

ABSTRACT Objective To identify the main determinants of food consumption among adult users of a public market in a capital of Northeastern Brazil. Methods A total of 198 diners in a public market, constituting a sample comprising 149 males and 49 females over 19 years of age, was interviewed using a pre-tested questionnaires from August 2018 to January 2019. Sociodemographic variables such as gender, age, place of origin, education and income, in addition to the determinants of food choices were evaluated. The analysis was performed using the Wilcoxon test (nonparametric) that compared the means of the dimensions involved in these choices according to gender and income. Results Sensory appeal, price and health were the main determinants of food choices. When compared by gender and income, there were significant differences regarding the attributes reviewed. Conclusion The factors that influenced food choice were: sensory appeal, price and health. Ethical issues were the ones that least interfered with food choice. Thus, such aspects must be taken into account for the development of public policies in the area of collective eating and environmental education. The factors that influenced food choice were: sensory appeal, price and health. Ethical issues were the ones that least interfered with food choice. Thus, such aspects must be taken into account for the development of public policies in the area of collective eating and environmental education.

https://doi.org/10.1590/1678-9865202033e190126 630 downloads

12.

Associação entre aleitamento materno e excesso de peso em pré-escolares
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Macêdo, Rivaldo da Costa

; Ramos, Carmen Viana

; Paiva, Adriana de Azevedo

; Martins, Maria do Carmo de Carvalho e

; Almeida, Camila Aparecida Pinheiro Landim

; Paz, Suzana Maria Rebêlo Sampaio da

Acta Paulista de Enfermagem

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2020, Volume 33 elocation eAPE20190025

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

Abstract Objective To analyze association between breastfeeding and overweight in preschoolers. Methods A cross-sectional study with 448 preschoolers from 10 Municipal Centers of Early Childhood Education in the city of Teresina, state of Piauí. A meeting was held with the parents, at which time the structured questionnaire with questions related to sociodemographic data and past feeding of the children was applied. Subsequently, the anthropometric measurements of the children (weight and height). Overweight (overweight + obesity) was considered when the z-score result was greater than or equal to +2. Children younger than +2 were classified as not overweight. The association between exclusive breastfeeding up to six months, exclusive breastfeeding up to four months and breastfeeding with the child’s nutritional status was analyzed using Pearson’s chi-square test (c2), while the prevalence ratio (PR) was estimated to quantify the associations between breastfeeding and nutritional status controlled by sociodemographic variables. All estimates and 95% confidence intervals were calculated using the robust variance Poisson regression model. Results The prevalence of overweight and the proportion of children who received exclusive breastfeeding until 6 months of age were 11.16% and 41.9%, respectively. Overweight was 2.5 times higher among non-breastfed children (95% CI: 1.09; 5.83). After controlling for sociodemographic variables, it was found that children older than 48 months were at high risk for overweight (PR: 1.69; 95% CI: 1.01; 2.85) compared to children younger than 48 months. months old (p = 0.04). Conclusion The present study demonstrated that breastfed newborns were protected against overweight.

Resumen Objetivo Analizar la elación entre la lactancia materna y el exceso de peso en niños preescolares. Métodos Estudio transversal con 448 niños preescolares de 10 Centros Municipales de Educación Infantil del municipio de Teresina, estado de Piauí. Se realizó una reunión con los padres, momento en que se aplicó el cuestionario estructurado con preguntas relativas a datos sociodemográficos y alimentación anterior de los niños. Posteriormente, se obtuvieron las medidas antropométricas de los niños (peso y estatura). Se consideró exceso de peso (sobrepeso + obesidad) cuando el resultado de la puntuación z fue mayor o igual a +2; y los menores a +2 se clasificaron como sin exceso de peso. El análisis de la relación entre lactancia materna exclusiva hasta los seis meses, lactancia exclusiva hasta los cuatro meses y lactancia materna con el estado nutricional del niño se realizó mediante la prueba c2 de Pearson . Para cuantificar las relaciones entre la lactancia materna y el estado nutricional controlado por las variables sociodemográficas se calculó la a razón de prevalencia (RP). Todas las estimaciones y los intervalos de confianza de 95% se calcularon utilizando el modelo de regresión de Poisson con varianza robusta. Resultados La prevalencia del exceso de peso y la proporción de los niños que recibieron lactancia materna exclusiva hasta los 6 meses de edad fue de 11,16% y 41,9%, respectivamente. El exceso de peso fue 2,5 veces más elevado en niños no amamantados (IC 95%: 1,09; 5,83). Luego del control de las variables sociodemográficas, se verificó que los niños mayores de 48 meses tuvieron un riesgo elevado de exceso de peso (RP: 1,69; IC 95%: 1,01; 2,85) con relación a los menores de 48 meses de edad (p = 0,04). Conclusión El presente estudio demostró que los niños que recibieron lactancia materna fueron protegidos contra el exceso de peso.

Resumo Objetivo Analisar associação entre aleitamento materno e excesso de peso em pré-escolares. Métodos Estudo transversal com 448 pré-escolares de 10 Centros Municipais de Educação Infantil do município de Teresina-PI. Realizou-se reunião com os pais, momento em que foi aplicado o questionário estruturado com questões relativas aos dados sociodemográficos e alimentação pregressa das crianças. Posteriormente, foram obtidas as medidas antropométricas das crianças (peso e altura). Foi considerado excesso de peso (sobrepeso + obesidade) quando o resultado do escore-z foi maior que ou igual a +2, e os menores que +2 foram classificados como sem excesso de peso. A análise da associação entre o aleitamento materno exclusivo até seis meses, aleitamento exclusivo até quatro meses e o aleitamento materno com o estado nutricional da criança foi feita utilizando-se o teste qui-quadrado de Pearson (c2), enquanto a razão de prevalência (RP) foi estimada para quantificar as associações entre o aleitamento materno e o estado nutricional controlado pelas variáveis sociodemográficas. Todas as estimativas e os intervalos de confiança de 95% foram calculados utilizando o modelo de regressão de Poisson com variância robusta. Resultados A prevalência do excesso de peso e a proporção das crianças que receberam o aleitamento materno exclusivo até os 6 meses de idade foi de 11,16% e 41,9%, respectivamente. O excesso de peso foi 2,5 vezes mais elevado entre as crianças não amamentadas (IC 95%: 1,09; 5,83); e, após o controle das variáveis sociodemográficas, verificou-se que as crianças maiores de 48 meses tiveram risco elevado para o excesso de peso (RP: 1,69; IC 95%: 1,01; 2,85) em relação aos menores de 48 meses de idade (p = 0,04). Conclusão O presente estudo demonstrou que as crianças que receberam aleitamento materno foram protegidas contra o excesso de peso.

https://doi.org/10.37689/acta-ape/2020ao0025 326 downloads

13.

Associação entre aleitamento materno e excesso de peso em pré-escolares
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Macêdo, Rivaldo da Costa

; Ramos, Carmen Viana

; Paiva, Adriana de Azevedo

; Martins, Maria do Carmo de Carvalho e

; Almeida, Camila Aparecida Pinheiro Landim

; Paz, Suzana Maria Rebêlo Sampaio da

Acta Paulista de Enfermagem

Journal Metrics
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2020, Volume 33 elocation eAPE20190025

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.37689/acta-ape/2020ao0025 2870 downloads

14.

Influence of Polymorphism of Vitamin D Receptor (Fok I) on Hypertension
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Nunes, Ivone Freires de Oliveira Costa

; Pinho, Flaviane Alves de

; Cruz, Maria do Socorro Pires e

; Paiva, Adriana de Azevedo

; Carvalho, Cecilia Maria Resende Gonçalves de

Brazilian Archives of Biology and Technology

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2020, Volume 63 elocation e20190403

Abstract: En | Text: En | PDF: En

Abstract Evidence suggests that polymorphisms in the gene encoding a vitamin D receptor might affect blood pressure. The objective of this systematic review was to investigate the association between hypertension and vitamin D receptor (Fok I) gene polymorphism. A literature search was performed according to the PRISMA guidelines using the MEDLINE®/PubMed, Scopus, Cochrane Library CENTRAL, SciELO, and LILACS databases. The quality of case-control or cohort studies and studies based on cross-sectional methodology was evaluated using the Newcastle-Ottawa Scale and the protocol of Loney and coauthors [25], respectively. In this systematic literature search, 215 publications were identified, of which 10 were analyzed, including seven case-control studies, two cross-sectional studies, and one cohort study. The association between Fok I polymorphism and hypertension was reported in 60% of the publications and the risk for hypertension was shown to be related to FF and ff genotypes. In addition, Fok I polymorphism was shown to increase plasma renin activity, which plays an important role in regulating blood pressure. However, no association was observed between Fok I polymorphism and serum vitamin D levels. In conclusion, Fok I polymorphism plays an important role in hypertension.

https://doi.org/10.1590/1678-4324-2020190403 685 downloads

15.

Effect of vitamin D3 supplementation on HIV-infected adults: a systematic review
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Teixeira, Nayra do Socorro Caldas Carvalho de Almeida

; Pereira, Beatriz de Mello

; Oliveira, Iara Katrynne Fonsêca

; Lima, Carlos Henrique Ribeiro

; Carvalho, Cecília Maria Resende Gonçalves de

; Nunes, Ivone Freires de Oliveira Costa

; Costa, Dorcas Lamounier

; Paiva, Adriana de Azevedo

Nutrición Hospitalaria

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oct 2019, Volume 36 N. 5 Pages 1205 - 1212

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Introduction: much evidence confirms that vitamin D may be associated with an improvement in CD4 cell counts in HIV-infected individuals, where antiretroviral therapy (ART) is used and associated with decreased 25(OH)D levels. Objective: to carry out a systematic review on the effect of vitamin D supplementation on HIV-infected adult patients. Methods: the research was conducted in the databases Science Direct, PubMed, BVS, Scielo Cochrane and Periods, from February to April 2018, with publication limit from 2000 to 2018, without restriction of gender, ethnicity and involving individuals with age older than 18 years. To evaluate the quality of the studies, we used the protocol Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) and the Jadad scale. Results: the search initially resulted in 198 articles. After the selection process 5 articles were identified as eligible, where they highlight that vitamin D supplementation may be an associated and effective intervention to reduce hypovitaminosis. ART reduces vitamin D3 levels and changes its metabolism, being associated with the risk of mortality. However, adequate levels of 25(OH)D are positively associated with the number of CD4 + cells and the reduction of infection levels. Conclusion: vitamin D supplementation promotes immune recovery. However, the cases analysed were few, insufficient to fully confirm the benefits and recommend supplementation. Therefore, intervention studies are needed to elucidate the role of vitamin D in human protection against HIV infections.

Resumen Introducción: muchas evidencias ratifican que la vitamina D puede estar asociada con la mejora de los niveles de células CD4 en individuos infectados por el VIH, tratados con terapia antirretroviral (ART) que se asocia a la disminución de los niveles de 25(OH)D. Objetivo: realizar una revisión sistemática sobre el efecto de la suplementación de vitamina D en pacientes adultos infectados con VIH. Métodos: la investigación fue realizada en las bases de datos Science Direct, PubMed, BVS, Scielo Cochrane y periódicos, de febrero a abril de 2018, con límite de publicación de 2000 a 2018, sin restricción de género, etnicidad y que involucra a individuos con edad mayores de 18 años. Para la evaluación de la calidad de los estudios, se utilizó el protocolo Preferred Reporting Items for Systematic Reviews y Meta-Analyzes (PRISMA) y la escala de Jadad. Resultados: la encuesta inicialmente resultó en 198 artículos. Después del proceso de selección, 5 artículos fueron identificados como elegibles, donde ponen de manifiesto que la suplementación con vitamina D puede ser una intervención asociada y eficaz para reducir la hipovitaminosis. La ART reduce niveles de la vitamina D3 y altera su metabolismo, estando asociada al riesgo de mortalidad. Sin embargo, los niveles adecuados de 25(OH)D están asociados positivamente al número de células CD4 + y la reducción de los niveles de infecciones. Conclusión: la suplementación de vitamina D promueve la recuperación inmunológica. Sin embargo, los casos analizados fueron pocos, insuficientes para confirmar totalmente los beneficios y recomendar la suplementación. Por lo tanto, estudios de intervención son necesarios para elucidar la actuación de la vitamina D en la protección humana contra las infecciones por el VIH.

https://doi.org/10.20960/nh.02647 448 downloads

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