ABSTRACT This study was conducted to evaluate the effects of Curcuma longa on the growth performance, intestinal integrity, and antimicrobial activity of chicks colonized by Salmonella Typhimurium. The study included 672 one-day-old male chicks of the CobbTM lineage, which were divided into eight treatment groups with 14 birds per group and six repetitions, for a total of 48 experimental units per treatment. A randomized 4×2 factorial design scheme (C. longa levels × inoculation by Salmonella Typhimurium) was used. Chicks were orally inoculated with 1.2×104 cfu/mL of Salmonella Typhimurium in 0.5 mL of 0.85% buffered saline solution. Curcuma was added to the feed of chicks at 0, 1, 2, and 3% for 35 days. Data were analyzed by analysis of variance and Tukey's test. Optimal feed conversion was observed in chicks given feed supplemented with 1% C. longa, regardless of infection, and 1% C. longa prevented intestinal colonization by Salmonella Typhimurium. Supplementation and bacterial infection influenced the histomorphometry and pH of the intestine. Bacterial infection reduced the intestinal pH, whereas C. longa supplementation increased the pH, but only in infected chicks. Thus, supplementation with 1% C. longa favors feed conversion, inhibits intestinal colonization by Salmonella Typhimurium, and does not alter intestinal integrity. In contrast, supplementation with 3% Curcuma longa decreases feed intake, affecting the performance of 35-day-old chicks.
Five hundred commercial male Cobb broilers were allotted in a randomized blocks design with five treatments, four replicates and 25 chicks per experimental unit in order to evaluate the effects of adding L-glutamine to the diet with no anticoccidial agents and growth promoters. Experimental diets contained L-glutamine at different levels (0.0; 5.0; 10.0; 15.0 or 20.0g/kg), through the experimental period. Experiment was conducted with broiler chicken from 1 to 42 days old. The parameters evaluated were feed intake, feed conversion ratio, body weight gain, mortality, digestibility coefficients of dry matter, crude protein and ether extract, carcass yield and intestinal mucosa structure of small intestine. The data obtained were submitted to polynomial regression analysis. Means were compared using Tukey test.Was considered a type I error set at P < 0.05. The level of L-glutamine in the diet influenced feed conversion ratio of broilers at 1-7 days old, which was improved at 10.0g/kgL glutamine. Carcass yield and digestibility coefficients of the diet were not affected by the levels of glutamine in the diet. Adding L-glutamine influenced crypt depth in small intestine of broilers at 18 and 42 days old. It is recommended the addition of 10.0g/kg L-glutamine to the pre-started diet.
Quinhentos frangos de corte machos da linhagem Cobb foram distribuídos em delineamento em blocos casualizados com cinco tratamentos, quarto repetições e 25 aves por unidade experimental para avaliar os efeitos da adição de L-glutamina na dieta das aves sem anticoccidiano e promotor de crescimento. As dietas experimentais continham L-glutamina em diferentes níveis (0,0;5,0;10,0;15.0 e 20,0g/kg). O experimento foi conduzido com frangos de corte de 1 a 42 dias de idade. As variáveis avaliadas foram consumo de ração, conversão alimentar, ganho de peso, mortaliade, coeficientes de digestibilidade da matéria seca, da proteína bruta e do extrato etéreo, rendimento de carcaça e morfometria do intestino delgado. Os dados foram submetidos à análise de regressão polinomial. As médias foram comparadas pelo teste Tukey. - Considerou-se o erro tipo I sendo P < 0,05. O nível de L-glutamina na dieta influenciou a conversão alimentar dos frangos de 1 a 7 dias de idade, sendo melhor com 10,0g/kg L-glutamina. Rendimento de carcaça e coeficientes de digestibilidade não foram afetados pelos níveis de glutamina na dieta. Adição de L-glutamina influenciou a profundidade de cripta do intestino delgado aos 18 e 42 dias de idade. Recomenda-se a adição de 10,0g/kg L-glutamina na dieta pré-inicial das aves.