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ABSTRACT This paper describes a method to reduce the shielding thickness in a high dose brachytherapy treatment room, with an Iridium-192 source, using the protocols established by the International Atomic Energy Agency in its Safety Report No. 47; calculating the volume of shielding material, without failing to comply with the radiation safety parameters established by the General Radiation Safety Regulations and regulations in force by the Comisión Nacional de Seguridad Nuclear y Salvaguardias, which acts as the regulatory body for the use of radioactive sources in Mexico. The shielding of the walls was determined as a function of room design, source activity, workload, use factor, number of weekly treatments, treatment time, and shielding material properties. The results show that the shielding volume can be reduced by 19.592% and 20.727% for five-point and eleven-point fractionation, respectively, for a Brachytherapy room with a maze.

RESUMEN El presente trabajo describe un método para reducir el grosor de blindaje en una sala de tratamiento de Braquiterapia de alta dosis con fuente de Iridio-192, utilizando los protocolos establecidos por el Organismo Internacional de Energía Atómica en su Informe de Seguridad No. 47; calculando el volumen de material de blindaje, sin incum plir con los parámetros de seguridad radiológica que establece el Reglamento General de Seguridad Radiológica y normatividad vigente por la Comisión Nacional de Seguridad Nuclear y Salvaguardias, quien funge como órgano regulador para el uso de fuentes radiactivas en México. Por lo que se determinó el grosor de las paredes en función al diseño de la sala, ubicación y actividad total de la fuente, así como, factor de ocupación en áreas adyacentes car ga de trabajo, factor de uso, número de tratamientos semanales, tiempo promedio de tratamiento y propiedades del material de blindaje. Mediante estos cálculos, se determinó que el volumen de blindaje se puede reducir un 19.592% y 20.727% para el fraccionamiento en cinco y once puntos, respectivamente, para una sala de Braquiterapia con laberinto.

https://doi.org/10.17488/rmib.42.3.4 46 downloads

Direct PCR of lesions suggestive of sporotrichosis in felines
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Gonsales, F.F.

; Fernandes, N.C.C.A.

; Mansho, W.

; Montenegro, H.

; Benites, N.R.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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sep 2020, Volume 72 N. 5 Pages 2002 - 2006

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A esporotricose é uma doença emergente e a incidência de esporotricose zoonótica tem aumentado, principalmente no Brasil; a maioria dos casos está relacionada à transmissão de gatos infectados. O diagnóstico definitivo da esporotricose felina é feito por cultura fúngica; no entanto, aguardar o longo período de cultura pode atrasar o início do tratamento. O objetivo deste estudo foi detectar e determinar as espécies de Sporothrix por PCR realizado diretamente das lesões de gatos, provenientes de área endêmica, nos quais a esporotricose fazia parte do diagnóstico diferencial. Um total de 87,1% dos casos foi positivo por PCR ou cultura fúngica para Sporothrix; 81,4% foram confirmados como S. brasiliensis por PCR, 71,4% por isolamento e 65,7% pelos dois métodos. Em conclusão, a análise direta por PCR de lesões sugestivas de esporotricose em gatos é um bom método para confirmar a infecção e determinar as espécies de Sporothrix, garantindo um diagnóstico rápido; esse método tem uma boa concordância com o isolamento fúngico.

https://doi.org/10.1590/1678-4162-11743 583 downloads

Desarrollo de una Escala de Prácticas y Concepciones de Evaluación de Profesores Universitarios (EPCEP)
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Peña, Percy P.

; Gonzalez, Carlos H.

; Montenegro, Helena L.

Formación universitaria

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dec 2019, Volume 12 N. 6 Pages 15 - 26

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: The objective of this article was the design and validation of an instrument that measures university professors’ assessment conceptions and practices (EPCEP). It was applied in a sample of 237 professors from a traditional regional private university belonging to the Faculties of Medicine, Engineering and Humanities. The Confirmatory Factor Analysis suggests a structure of four factors with a good fit that coincides with what it is hypothesized in the literature. It is concluded that the EPCEP has adequate psychometric properties for its use in a teaching population. However, research must be continued to improve reliability of the instrument. This easy-to-use instrument can contribute to the understanding of the assessment profiles of professors in the context of higher education.

Resumen: El objetivo de este estudio fue el diseño y validación de un instrumento que mide concepciones y prácticas de evaluación de profesores universitarios (EPCEP). Se aplicó en una muestra (n=237) de académicos de una universidad privada tradicional regional pertenecientes a las facultades de Medicina, Ingeniería y Humanidades. El Análisis Factorial Confirmatorio sugiere una estructura de cuatro factores con un buen ajuste que coincide con lo hipotetizado en la literatura. Se concluye que el EPCEP posee adecuadas propiedades psicométricas para su uso en población docente. Sin embargo, se debe continuar la investigación para mejorar su confiabilidad. Este instrumento de fácil aplicación puede contribuir a la comprensión de los perfiles de evaluación de los académicos en el contexto de la educación superior.

1033 downloads

Evaluación de la calidad composicional, microbiológica y sanitaria de la leche cruda en el segundo tercio de lactancia en vacas lecheras
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Jurado-Gámez, H.

; Muñoz-Domínguez, L.

; Quitiaquez-Montenegro, D.

; Fajardo-Argoti, C.

; Insuasty-Santácruz, E.

Revista de la Facultad de Medicina Veterinaria y de Zootecnia

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apr 2019, Volume 66 N. 1 Pages 53 - 66

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Introducción: Uno de los parámetros más importantes asociados a la producción de leche y su transformación es contar con condiciones higiénico-sanitarias adecuadas que permitan mejorar las condiciones del productor y empresas transformadoras y, por ende, garantizar inocuidad alimentaria al consumidor garantizando su bienestar y salud. Objetivo: Se evaluaron características composicionales, microbiológicas y sanitarias de leche cruda durante el segundo tercio de lactancia en vacas lecheras. Materiales y métodos: Se tomaron muestras de leche por duplicado cada 10 días a siete vacas lecheras durante su segundo tercio de lactancia. Posteriormente, se realizaron las siguientes pruebas: análisis composicional, adulterantes, presencia de antibióticos, recuento de células somáticas (RCS/ ml), identificación de Staphylococcus aureus y antibiograma por el método de Kirby-Bauer. Resultados: Se detectó la presencia de Staphylococcus aureus en el 66,2% de las muestras y 4,6% resultaron positivas para Listeria sp. No hubo presencia de antibióticos, peróxidos y almidones. Se evidenciaron muestras positivas para cloruros y neutralizantes, además se determinó que por cada kilogramo de leche se obtiene 30, 25 y 84 g de proteína, caseína y sólidos no grasos (SNG), respectivamente; donde la caseína representó el 83% de la proteína. Para el caso del RCS/ml se encontraron valores superiores a un millón de RCS/ml. Conclusiones: Para el caso estudiado la calidad composicional, sanitaria y microbiológica de la leche cruda en el segundo tercio de lactancia en vacas lecheras no es adecuada debido a que se obtuvieron valores que sobrepasan algunos lineamientos de la Norma Técnica Colombiana (NTC) 399 de 2002, en la cual se establece un conteo de mesófilos y de células somáticas (RCS/ml) máximo de 700.000/ml de leche cruda, a partir del cual se debe descartar el consumo de leche o su transformación.

ABSTRACT Introduction: One of the most important parameters associated with the production of milk and its transformation, is to have adequate hygienic-sanitary conditions in terms of milk quality that allow improving the conditions of the producer and processing companies, and therefore to provide food safety to the consumers, guaranteeing their well-being and health. Objetive: Compositional, microbiological and sanitary characteristics of raw milk were evaluated during the second third of lactation in dairy cows. Materials and methods: Two milk samples were taken every 10 days from 7 dairy cows during their second third of lactation. Then the following tests were carried out: compositional analysis, adulterants, presence of antibiotics, somatic cell count (SCC/mL), identification of Staphylococcus aureus and antibiogram by the Kirby-Bauer method. Results: Staphylococcus aureus was evidenced in 66.2% of the samples, and 4.6% of them gave positive for Listeria sp. No traces of antibiotics, peroxides and starches were found. Positive samples were found for chlorides and neutralizers, and it was determined that for each kilogram of milk, 30, 25 and 84 grams of protein, casein and non-fatty solids (NFS) were obtained, with 83% of the protein formed by casein. In the case of SCC/mL, values higher than one million SCC/mL were found. Conclusions: The compositional, sanitary and microbiological quality of the studied raw milk in the second third of lactation in dairy cows was not adequate, because values found lied above the Colombian technical standard 399 of 2002, which establishes a maximum of mesophile and somatic cell count (SCC/ mL) of 700000/ml in raw milk, therefore not allowing its consumption and transformation.

https://doi.org/10.15446/rfmvz.v66n1.79402 1620 downloads

SIMULATION OF SODIUM AND POTASSIUM DYNAMICS BY THE HYDRUS 2D MODEL IN A HAPLIC PLANOSOL VIA RESIDUE WATER
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Andrade, Carolyne W. L. de

; Montenegro, Suzana M. G. L.

; Miranda, Jarbas H. de

; Montenegro, Abelardo A. de A.

; Assis, Fred M. C. V. de

Engenharia Agrícola

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dec 2018, Volume 38 N. 6 Pages 874 - 884

Abstract: En | Text: En | PDF: En

ABSTRACT The application of chemical substances to the soil together with little attention given to the possible environmental impacts, transformed the environment into a recipient of waste. The aim of this study was to simulate the movement of water and solutes (sodium and potassium together) using the STANMOD and HYDRUS-2D models in a typical Haplic Planosol under the application of wastewater via surface irrigation under different flow rates. The experiment was conducted in the laboratory by miscible displacement tests, first using columns with deformed soil under saturation and steady water flow conditions, at a rate of 11.7 cm3 min-1, to obtain transport parameters of sodium and potassium ions, and in the applied residual water, the values of 475 and 76.6 mg dm-3, respectively. The transport parameters were estimated from the numerical adjustment of effluent distribution curves, using the STANMOD model. In a second step, the HYDRUS-2D model was applied to simulate the volumetric soil moisture distribution profiles, as well as the ion concentrations in the wet bulb. Considering the results obtained, we can see that there was considerable interaction between the solutes and the soil. The value of the delay parameter was higher for the sodium when compared to the potassium, reflecting its greater adsorption and the processes of exchange between the solute and the soil. The results suggested the need for adequate soil management in order to avoid future soil sodification and, in view of the application of HYDRUS-2D, it was verified that the model presented a satisfactory performance in the simulation of the displacement of the ions, after 1, 5 and 10 hours of wastewater application.

https://doi.org/10.1590/1809-4430-eng.agric.v38n6p874-884/2018 935 downloads

Empowerment of the mothers of children in a pediatric intensive care unit
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Azevedo, Monique de Sales Norte

; Oliveira, Isabel Cristina dos Santos

; Souza, Tania Vignuda de

; Moraes, Juliana Rezende Montenegro Medeiros de

; Martinez, Elena Araujo

; Araújo, Beatriz da Silva

Revista Brasileira de Enfermagem

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jun 2018, Volume 71 N. 3 Pages 998 - 1006

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: to analyze the process of empowerment of the mothers of children hospitalized in a pediatric intensive care unit (PICU) according to Cheryl H. Gibson’s framework. Method: a qualitative study with a non-directive interview in groups was carried out with 14 mothers in the PICU of a pediatric teaching hospital in the state of Rio de Janeiro, whose data were submitted to thematic analysis. Results: all mothers underwent at least one phase of the process of empowerment. Some of them achieved the phase of participatory competence in the care for their children, being heard by the team and expressing their needs, opinions, and questions. Final considerations: attentive listening and information sharing with mothers is necessary, in order to provide essential support so that they undergo the process of empowerment, thus involving themselves in care and decision-making regarding their children.

RESUMEN Objetivo: analizar el proceso de empoderamiento de madres de niños internados en una Unidad de Terapia Intensiva Pediátrica (UTIP) a la luz del referencial de Cheryl H. Gibson. Método: investigación cualitativa, con entrevista no directiva, en grupo, de 14 madres de una UTIP de hospital universitario pediátrico de Rio de Janeiro, cuyos datos fueron sometidos a análisis temático. Resultados: todas las madres pasaron, por, al menos, una fase del proceso de empoderamiento. Parte de ellas alcanzó la fase de la competencia participativa en el cuidado del niño, siendo oídas por el equipo y manifestando necesidades, opiniones y cuestionamientos. Consideraciones finales: es necesario escuchar atentamente y compartir la información con las madres, de manera de brindar las ayudas esenciales para que pasen por el proceso de empoderamiento y, así, involucrarse en la atención y en las tomas de decisiones relacionadas con sus hijos.

RESUMO Objetivo: analisar o processo de empoderamento de mães de crianças internadas numa Unidade de Terapia Intensiva Pediátrica (UTIP) à luz do referencial de Cheryl H. Gibson. Método: pesquisa qualitativa, com entrevista não diretiva, em grupo, de 14 mães de uma UTIP de um hospital universitário pediátrico do Rio de Janeiro, cujos dados foram submetidos à análise temática. Resultados: todas as mães passaram por, pelo menos, uma fase do processo de empoderamento. Parte delas atingiu a fase da competência participativa no cuidado ao filho, sendo ouvida pela equipe e manifestando suas necessidades, opiniões e questionamentos. Considerações finais: é necessário escuta atenta e compartilhamento de informações com as mães, de modo a proporcionar os subsídios essenciais para que passem pelo processo de empoderamento e, assim, envolvam-se nos cuidados e nas tomadas de decisão relacionadas a seus filhos.

https://doi.org/10.1590/0034-7167-2016-0689 13 downloads

Empowerment of the mothers of children in a pediatric intensive care unit
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Azevedo, Monique de Sales Norte

; Oliveira, Isabel Cristina dos Santos

; Souza, Tania Vignuda de

; Moraes, Juliana Rezende Montenegro Medeiros de

; Martinez, Elena Araujo

; Araújo, Beatriz da Silva

Revista Brasileira de Enfermagem

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may 2018, Volume 71 N. 3 Pages 998 - 1006

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0034-7167-2016-0689 2026 downloads

Controversial issues in the management of hyperprolactinemia and prolactinomas – An overview by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism
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Vilar, Lucio

; Abucham, Julio

; Albuquerque, José Luciano

; Araujo, Luiz Antônio

; Azevedo, Monalisa F.

; Boguszewski, Cesar Luiz

; Casulari, Luiz Augusto

; Cunha Neto, Malebranche B. C.

; Czepielewski, Mauro A.

; Duarte, Felipe H. G.

; Faria, Manuel dos S.

; Gadelha, Monica R.

; Garmes, Heraldo M.

; Glezer, Andrea

; Gurgel, Maria Helane

; Jallad, Raquel S.

; Martins, Manoel

; Miranda, Paulo A. C.

; Montenegro, Renan M.

; Musolino, Nina R. C.

; Naves, Luciana A.

; Ribeiro-Oliveira Júnior, Antônio

; Silva, Cíntia M. S.

; Viecceli, Camila

; Bronstein, Marcello D.

Archives of Endocrinology and Metabolism

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mar 2018, Volume 62 N. 2 Pages 236 - 263

Abstract: En | Text: En | PDF: En

ABSTRACT Prolactinomas are the most common pituitary adenomas (approximately 40% of cases), and they represent an important cause of hypogonadism and infertility in both sexes. The magnitude of prolactin (PRL) elevation can be useful in determining the etiology of hyperprolactinemia. Indeed, PRL levels > 250 ng/mL are highly suggestive of the presence of a prolactinoma. In contrast, most patients with stalk dysfunction, drug-induced hyperprolactinemia or systemic diseases present with PRL levels < 100 ng/mL. However, exceptions to these rules are not rare. On the other hand, among patients with macroprolactinomas (MACs), artificially low PRL levels may result from the so-called “hook effect”. Patients harboring cystic MACs may also present with a mild PRL elevation. The screening for macroprolactin is mostly indicated for asymptomatic patients and those with apparent idiopathic hyperprolactinemia. Dopamine agonists (DAs) are the treatment of choice for prolactinomas, particularly cabergoline, which is more effective and better tolerated than bromocriptine. After 2 years of successful treatment, DA withdrawal should be considered in all cases of microprolactinomas and in selected cases of MACs. In this publication, the goal of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism (SBEM) is to provide a review of the diagnosis and treatment of hyperprolactinemia and prolactinomas, emphasizing controversial issues regarding these topics. This review is based on data published in the literature and the authors' experience.

https://doi.org/10.20945/2359-3997000000032 36158 downloads

Effects of extracts from Maytenus on Aegorhinus superciliosus (Coleoptera: Curculionidae) and Hippodamia convergens (Coleoptera: Coccinellidae)
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Zavala H, Andrea

; Hormazabal U, Emilio

; Montenegro R, Gloria

; Rosalez V, Marlene

; Quiroz C, Andrés

; Paz R, Cristian

; Rebolledo R, Ramón

Revista Colombiana de Entomología

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dec 2017, Volume 43 N. 2 Pages 233 - 244

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Se evaluó el efecto insecticida de cinco extractos etanólicos producidos a partir de tres especies del género Maytenus: hojas (HMB), corteza de (CMB) y semillas (SMB) de M. boaria, hojas de M. disticha (HMD) y hojas de M. magellanica sobre el escarabajo Hippodamia convergens (Coleoptera: Coccinellidae) y en la plaga de la zarzamora Aegorhinus superciliosus (Coleoptera: Curculionidae). También se evaluó el efecto anti-alimentario de los extractos sobre este último. Se utilizó aplicación residual, con cinco concentraciones para cada especie de insecto y diez repeticiones en cada ensayo. Para evaluar la acción anti-alimentaria sobre adultos de A. superciliosus, se establecieron experimentos de elección (E) y sin elección (NE) para determinar el porcentaje de área foliar consumida. Los ensayos duraron 120 horas, con la mortalidad y el efecto anti-alimentario monitoreados cada 24 horas. El mayor porcentaje de mortalidad en las dos especies de insectos se registró con el extracto etanólico de SMB: H. convergens presentó 82 % con una LC50: 32 mg/ml, mientras que A. superciliosus presentó 85 % en el ensayo de elección y 86 % en el ensayo de no elección, con una LC50: 23 mg/ml. En ambos ensayos, la mortalidad aumentó con el tiempo de exposición, alcanzando su máximo a las 120 horas. La menor mortalidad se obtuvo con el extracto de CMB en el ensayo de elección (C) y con el extracto de HMM en el ensayo de no elección (NE). En el ensayo de elección, el mayor porcentaje de área foliar consumida se registró con extracto de CMB, mientras que en el ensayo de no elección el mayor porcentaje de consumo fue con el extracto de HMM, que presentó valores más altos incluso que el control sin aplicación. El menor porcentaje de hojas consumido, en ambos ensayos, se registró con el extracto de SMB en las concentraciones más altas (20 y 30 % p/v).

Abstract The insecticidal effects of five ethanolic extracts produced from three species of the genus Maytenus: M. boaria leaf (MBL), M. boaria bark (MBB), M. boaria seed (MBS), M. disticha leaf (MDL) and M. magellanica leaf (MML) were evaluated on the lady beetle Hippodamia convergens (Coleoptera: Coccinellidae) and on the pest of berry Aegorhinus superciliosus (Coleoptera: Curculionidae). The anti-feeding effects of the extracts on the latter were also evaluated. Residual application was used, with five concentrations for each species of insect and ten replications of each assay. To evaluate anti-feeding action in adult A. superciliosus, choice (C) and no-choice (NC) experiments were established to determine the percentage of leaf area consumed. The assays lasted for 120 hours, with the mortality and anti-feeding effect monitored every 24 hours. The highest percentage of mortality in the two insect species was recorded with the MBS ethanolic extract: H. convergens presented 82 %, with LC50: 32 mg/ml; while A. superciliosus presented 85 % in the choice assay and 86 % in the no-choice assay, with LC50: 23 mg/ml. In both assays, the mortality increased with exposure time, reaching its highest at 120 hours. The lowest mortality was obtained with MBB extract in choice (C) and with MML extract in no-choice (NC) assays. In the choice assay, the highest percentage of leaf area consumed was recorded with MBB extract, while in the no-choice assay the highest percentage of consumed was with MML extract, which presented higher values even than the control with no application. The lowest leaf percentage consumed, in both assays, was recorded with MBS extract at the highest concentrations (20 and 30 % w/v).

https://doi.org/10.25100/socolen.v43i2.5948 266 downloads

10.

Salud cardiovascular en habitantes de Atahualpa: características y correlatos.
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Del Brutto, Oscar H.

; Mera, Robertino M.

; Santamaría, Milton

; Castillo, Pablo

; Zambrano, Mauricio

; Feraud, Scheny

; Barberán, Pedro

; Montenegro, Jipson J

; Peñaherrera, Ernesto

; Pow-Chon-Long, Freddy

; Montalván, Martha

; Tettamanti, Daniel

; Santibáñez, Rocío

; Del Brutto, Victor J.

Revista Ecuatoriana de Neurología

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aug 2017, Volume 26 N. 2 Pages 101 - 110

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Stroke and cardiovascular diseases will be the next epidemics in Latin America due to changes in lifestyle and increased life expectancy. Knowledge of cardiovascular health (CVH) status of the population is mandatory to implement cost-effective strategies directed to reduce the burden of vascular diseases in the region. In the Atahualpa Project, we assessed the CVH status of participants using the metrics proposed by the American Heart Association. The basal study included 616 subjects free of stroke and ischemic heart disease aged ≥40 years. Of these, 2.1% had ideal, 28.1% had intermediate and 69.8% had poor CVH status. Poorest metrics were blood pressure, fasting glucose, and BMI. The odds for having a poor CVH status were increased in persons aged ≥ 60 years and in those with only primary school education. Then, we compared our results with the Hispanic population of the Northern Manhattan Stroke Study (NOMAS), and found that Atahualpa residents had significantly better metrics than those enrolled in the NOMAS, with the exception of fasting glucose levels. Likewise, the odds for having 5 to 7 ideal metrics were also better in Atahualpa residents, irrespective of age. We also conducted a case-control study to assess the CVH status of Atahualpa residents according to their living arrangements, and found that social isolation was associated with a worse CVH status in this population. A couple of studies showed correlation between some sleep related disorders and poor CVH status. We have also started an ongoing program called “known your numbers”, which, together with community talks, is directed to improve the CVH status and to reduce the burden of vascular diseases in the region.

RESUMEN Las enfermedades vasculares son consideradas como las nuevas epidemias de salud en América Latina debido al aumento en la expectativa de vida y a cambios en el estilo de vida de sus habitantes. El conocimiento del estado de salud cardiovascular (SCV) de estas poblaciones es mandatorio para implementar estrategias costo-efectivas dirigidas a reducir la prevalencia de estas enfermedades en la región. En el Proyecto Atahualpa se ha valorado el estado de SCV de los participantes, utilizando los marcadores de salud propuestos por la Asociación Americana del Corazón. El estudio basal incluyó 616 sujetos libres de enfermedad cerebrovascular y cardiopatía isquémica, con edad ≥40 años. De estos, el 2.1% tuvieron un estado de salud ideal, el 28.1% intermedio y el 69.8% pobre. Los peores marcadores incluyeron presión arterial, glucosa en ayunas e índice de masa corporal. La posibilidad de tener un estado de SCV pobre estuvo aumentada en sujetos ≥60 años y en aquellos con escolaridad primaria. Luego, comparamos el estado de SCV de nuestra población con la de hispanos enrolados en el NOMAS, y encontramos que los residentes de Atahualpa tuvieron mejores marcadores de salud, con excepción de los niveles de glucosa en ayunas. La posibilidad de tener 5-7 marcadores en rango ideal fue más elevada en los residentes de Atahualpa, independientemente de la edad. También realizamos un estudio para valorar la SCV dependiendo del aislamiento social y encontramos que el vivir solo se asoció con un peor estado de SCV. Otros estudios mostraron relación entre ciertas patologías del sueño y un peor estado de SCV. Finalmente, hemos empezado el programa “conoce tus números”, el cual sumado a charlas comunitarias, se encuentra dirigido a mejorar la SCV de los residentes de Atahualpa y reducir la incidencia de eventos vasculares en la región.

14 downloads

11.

Influence of the ventilatory mode on acute adverse effects and facial thermography after noninvasive ventilation
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Pontes, Suzy Maria Montenegro

; Melo, Luiz Henrique de Paula

; Maia, Nathalia Parente de Sousa

; Nogueira, Andrea da Nóbrega Cirino

; Vasconcelos, Thiago Brasileiro

; Pereira, Eanes Delgado Barros

; Bastos, Vasco Pinheiro Diógenes

; Holanda, Marcelo Alcantara

Jornal Brasileiro de Pneumologia

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apr 2017, Volume 43 N. 2 Pages 87 - 94

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Comparar a incidência e a intensidade de efeitos adversos agudos e a variação da temperatura da pele da face através da termografia após a aplicação de ventilação não invasiva (VNI). Métodos: Foram incluídos 20 voluntários sadios, de ambos os gêneros, submetidos à VNI com máscara oronasal por 1 h e divididos aleatoriamente em dois grupos de acordo com o modo ventilatório: bilevel positive airway pressure (BiPAP) ou continuous positive airway pressure (CPAP). A termografia da face foi realizada para determinar a temperatura na região de contato da máscara e no dorso do nariz em momentos diferentes. Os voluntários preencheram um questionário de efeitos adversos após a retirada da VNI. Resultados: A incidência e a intensidade dos efeitos adversos agudos foram maiores naqueles submetidos a BiPAP em relação aos submetidos a CPAP (16,1% vs. 5,6%). A análise termográfica evidenciou um esfriamento significativo da pele facial nas duas regiões de estudo imediatamente após a retirada da máscara. Os efeitos adversos agudos em maior intensidade ocorreram predominantemente no grupo de participantes cuja redução da temperatura média no dorso do nariz foi menor (14,4% vs. 7,2%). A análise visual termográfica de zonas de esfriamento e aquecimento na face identificou regiões de hipoperfusão ou hiperemia reativa. Conclusões: O uso do modo BiPAP associou-se a maior incidência e intensidade de efeitos adversos agudos associados à VNI. Houve associação entre efeitos adversos agudos e menor esfriamento da pele do dorso do nariz imediatamente após a retirada da máscara. A termografia cutânea pode ser uma ferramenta adicional na detecção de efeitos adversos na pele da face associados ao uso da VNI.

ABSTRACT Objective: To compare the incidence and intensity of acute adverse effects and the variation in the temperature of facial skin by thermography after the use of noninvasive ventilation (NIV). Methods: We included 20 healthy volunteers receiving NIV via oronasal mask for 1 h. The volunteers were randomly divided into two groups according to the ventilatory mode: bilevel positive airway pressure (BiPAP) or continuous positive airway pressure (CPAP). Facial thermography was performed in order to determine the temperature of the face where it was in contact with the mask and of the nasal dorsum at various time points. After removal of the mask, the volunteers completed a questionnaire about adverse effects of NIV. Results: The incidence and intensity of acute adverse effects were higher in the individuals receiving BiPAP than in those receiving CPAP (16.1% vs. 5.6%). Thermographic analysis showed a significant cooling of the facial skin in the two regions of interest immediately after removal of the mask. The more intense acute adverse effects occurred predominantly among the participants in whom the decrease in the mean temperature of the nasal dorsum was lower (14.4% vs. 7.2%). The thermographic visual analysis of the zones of cooling and heating on the face identified areas of hypoperfusion or reactive hyperemia. Conclusions: The use of BiPAP mode was associated with a higher incidence and intensity of NIV-related acute adverse effects. There was an association between acute adverse effects and less cooling of the nasal dorsum immediately after removal of the mask. Cutaneous thermography can be an additional tool to detect adverse effects that the use of NIV has on facial skin.

https://doi.org/10.1590/s1806-37562016000000172 3730 downloads

12.

Spatial variability of Regosol chemical atributes in guava management with neem under semi-arid conditions
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Castro, Douglas B.

; Pedrosa, Elvira M. R.

; Montenegro, Abelardo A. A.

; Rolim, Mario M.

; Leitão, Diego A. H. S.

; Oliveira, Ana Karina S.

Revista Brasileira de Engenharia Agrícola e Ambiental

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jul 2016, Volume 20 N. 7 Pages 618 - 624

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Considerando a importância do cultivo de goiabeiras (Psidium guajava) para o nordeste do Brasil e os benefícios da aplicação da torta de nim nas características do solo, avaliou-se o efeito da aplicação de torta de nim nos atributos químicos de um Neossolo Regolítico cultivado com goiabeiras irrigadas no semiárido de Pernambuco. Para as avaliações foram usadas duas áreas (área 1 - com nim; área 2 - sem nim) e três períodos, antes da aplicação do nim, 90 dias após a primeira aplicação e 90 dias após a segunda aplicação; assim, 96 amostras de solo foram coletadas em duas malhas regulares de 8 × 6 pontos amostrais e realizadas análises do teor de carbono orgânico total, pH, teores de sais solúveis (Na+, K+, Ca2+e Mg2+), nitrogênio total e taxa de evolução C-CO2 do solo. O modelo esférico foi o que melhor se ajustou às variáveis estudadas seguido pelo gaussiano, com alcances que variaram de 12 a 60,5 m. A incorporação da torta de nim aumentou a variabilidade espacial e a oferta dos atributos de solo estudados.

ABSTRACT Considering the relevant importance of guava (Psidium guajava) in Northeastern Brazil along with the benefits of neem cake amendments on soil characteristics, this work evaluated the effects of neem cake on chemical attributes of a Regosol under irrigated guava orchard in an alluvial valley of Pernambuco semi-arid region. Evaluations were carried out in two areas (area 1 - with neem cake; area 2 - without neem cake) at three periods: before the first application of neem cake, 90 days after the first application and 90 days after the second application. A regular 8 × 6-point grid was designed in each area and the soil was sampled for total organic carbon, pH, soluble salts (Na+, K+, Ca2+ and Mg2+) and total nitrogen contents, as well as soil C-CO2 evolution rate in soil. Geostatistical analysis pointed out the spherical model as the best fit to the studied variables, followed by the Gaussian model, with ranges from 12 to 60.5 m. Neem cake incorporation increased spatial variability and the contents of the evaluated soil chemical attributes.

https://doi.org/10.1590/1807-1929/agriambi.v20n7p618-624 913 downloads

13.

Dabigatran en plasma: tiempos de trombina diluido, Ecarin y veneno de víbora de Russell diluido
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Martinuzzo, Marta

; Duboscq, Cristina

; López, Marina Sol

; Montenegro, Marina

; Viñuales, Susana

; Girardi, Beatriz

; Penchasky, Diana

; Otero, Victoria

; Ceresetto, José

; Stemmelin, German

; Barrera, Luis

; Otaso, Juan Carlos

; Oyhamburu, José

Acta bioquímica clínica latinoamericana

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jun 2016, Volume 50 N. 2 Pages 193 - 203

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Os objetivos do trabalho foram verificar a qualidade analítica do ensaio tempo de trombina diluído (DTI) para medição da concentração plasmática (cc) de dabigatrana, comparando dois coagulômetros de detecção foto-óptica, comparar os resultados com o tempo de Ecarina (ECT) e correlacionar as cc com os testes básicos de coagulação Tempo de protrombina (TP), APTT e Tempo de trombina (TT), e tempo de veneno de víbora de Russell com fosfolipídios concentrados (DRVVTC). Foram tomadas 43 amostras de plasma no vale (10-14 h. da última toma) de 40 pacientes que recebiam dabigatrana. DTI e ECT apresentaram (%) repetitividade <5,4% e <7,5%, CV interensaio <6% e <9%, respectivamente, no protocolo EP15A2, aceitáveis para um Erro Total permitido (TEa) <15%. Cc medidas em pacientes: mediana 83 (4-945) ng/mL. Comparação de equipamentos ACL TOP 300 e 500: resultados equivalentes por procedimento alternativo de comparação de métodos. Comparação ECT vs. DTI: satisfatória por regressão de Deming (pendente 1,143, ordenada à origem -19,33). Correlações cc vs. APTT, TP e DRVVTC: moderadas e não lineares tendendo a plateau a cc>350 ng/mL, r2 0,59; 0,66 e 0,59, respectivamente. O TT é extremamente sensível: >120 s a cc 50 ng/mL. DTI apresentou um bom desempenho analítico e permitiu quantificar dabigatrana plasmática a cc baixas e altas em ambos os equipamentos utilizados. ECT apresentou resultados comparáveis com DTI. Verifica-se uma correlação moderada entre cc de dabigatrana e os testes clássicos e DRVVTC, podendo ser estimadores de cc a partir dos 50 ng/mL.

The aims of the study were to verify the analytical performance of Dilute Thrombin Time (DTI) test to measure plasma dabigatran concentration (cc) in two photo-optical coagulometers, compare Ecarin clotting Time (ECT) and DTI results, and correlate cc with classical coagulation tests: prothrombin time (PT), APTT, thrombin time (TT) and diluted Russell Viper Venom Time tests with high phospholipid concentration (DRVVTC). Forty three plasma samples from 40 patients taking dabigatran were drown at through (10-14 hs.since last dose). DTI and ECT showed repetitivity (%) <5.4% and <7.5%, interassay CV <6% and <9%, respectively, following EP15A2 protocol, acceptable considering a Allowed Total Error (TEa)<15%. Patients` cc: median 83 (4-945) ng/mL. The comparison between ACL TOP 300 and 500 coagulometers showed equivalent results by using the alternative method comparison test. ECT vs. DTI: acceptable by Deming`s regression (slope 1.143, Y insert -19.33). cc vs. APTT, TP and DRVVTC: nonlinear and moderate correlations with plateau reached at cc >350 ng/mL, r2 0.59, 0.66 y 0.59, respectively. TT is extremely prolonged at cc >50 ng/mL. In conclusion: DTI showed a good analytical performance in both coagulometers. ECT showed comparable results to DTI. We verified that dabigatran cc presented moderate correlations with PT, APTT and DRVVTC, and that these tests could only qualitative estimate cc >50 ng/mL.

Los objetivos del trabajo fueron verificar la calidad analítica del ensayo tiempo de trombina diluido (DTI) para medición de la concentración plasmática (cc) de dabigatran comparando dos coagulómetros de detección foto-óptica, comparar los resultados con el tiempo de Ecarin (ECT) y correlacionar las cc con las pruebas básicas de coagulación Tiempo de protrombina (TP), APTT y Tiempo de trombina (TT), y tiempo de veneno de víbora de Russell con fosfolípidos concentrados (DRVVTC). Se tomaron 43 muestras de plasma en el valle (10-14 h de la última toma) de 40 pacientes que recibían dabigatran. DTI y ECT presentaron (%) repetitividad <5,4% y <7,5%, CV interensayo <6% y <9%, respectivamente, en el protocolo EP15A2, aceptables para un Error Total permitido (TEa) <15%. Las cc medidas en pacientes fueron: mediana 83 (4-945) ng/mL. La comparación de equipos ACL TOP 300 y 500 dio resultados equivalentes por procedimiento alternativo de comparación de métodos. La comparación ECT vs. DTI fue satisfactoria por regresión de Deming (pendiente 1,143, ordenada al origen -19,33). Las correlaciones de cc vs. APTT, TP y DRVVTC fueron moderadas y no lineales tendiendo a plateau a cc>350 ng/mL, r2 0,59, 0,66 y 0,59, respectivamente. El TT fue extremadamente sensible: >120 s a cc 50 ng/mL. DTI presentó un buen desempeño analítico y permitió cuantificar dabigatran plasmático a cc bajas y altas en ambos equipos utilizados. ECT presentó resultados comparables a DTI. Se verifica una correlación moderada entre cc de dabigatran y las pruebas clásicas y DRVVTC, pudiendo ser estimadores de cc a partir de los 50 ng/mL.

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14.

Dinâmica do uso e ocupação do solo em uma bacia hidrográfica do semiárido brasileiro
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Coelho, Victor H. R.

; Montenegro, Suzana M. G. L.

; Almeida, Cristiano das N.

; Lima, Eduardo R. V. de

; Ribeiro Neto, Alfredo

; Moura, Glawbber S. S. de

Revista Brasileira de Engenharia Agrícola e Ambiental

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jan 2014, Volume 18 N. 1 Pages 64 - 72

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

As mudanças no uso e na ocupação do solo, provocadas pelas ações antrópicas, têm gerado grandes impactos nas paisagens. Esses impactos podem ser mitigados através do monitoramento do uso e da cobertura do solo utilizando-se informações espaço-temporais das modificações ocorridas na paisagem. Este trabalho apresenta uma análise espaço-temporal detalhada da dinâmica do uso e ocupação do solo da bacia hidrográfica do riacho São Paulo, localizada na região semiárida do Estado de Pernambuco, entre os anos de 1991 e 2010. Partindo da classificação de três imagens de satélite dos anos de 1991, 2000 e 2010, foram utilizadas matrizes de transição, associadas à álgebra de mapas e métricas da paisagem. Os resultados mostraram que durante o período estudado as classes de uso e ocupação do solo passaram por uma grande transição, com a substituição progressiva das áreas de vegetação de caatinga aberta por áreas com pastagem/agricultura. Junto com o rápido crescimento da classe pastagem/agricultura, a paisagem predominante de vegetação nativa foi sendo substituída por uma paisagem cada vez mais devastada, heterogênea e fragmentada, como mostraram os índices das métricas da paisagem.

The changes in the use and occupation of land, caused by human actions, have created major impacts on the landscapes. These impacts can be mitigated by monitoring the use and land cover, using spatial and temporal information of the changes occurring in the landscape. This paper presents a detailed analysis of spatial and temporal dynamics of land use and occupation of the stream São Paulo watershed, located in the semiarid region of Pernambuco State, during the period from 1991 to 2010. Based on the classification of three satellite images for the years 1991, 2000 and 2010, transition matrices were used associated with the algebra of maps, and landscape metrics. The results showed that during the studied period, the classes of land use and occupation went through a major transition, with the gradual replacement of sparse area of 'caatinga' vegetation by grazing areas/agriculture. Along with the rapid growth of the grazing areas/agriculture class, the predominant landscape of native vegetation has been replaced by a landscape increasingly devastated, fragmented and heterogeneous, as shown by the index of landscape metrics.

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15.

ADHD in idiopathic epilepsy
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Duran, Marcos H. C.

; Guimarães, Catarina A.

; Montenegro, Maria Augusta

; Neri, Marina L.

; Guerreiro, Marilisa M.

Arquivos de Neuro-Psiquiatria

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jan 2014, Volume 72 N. 1 Pages 12 - 16

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Nosso objetivo foi clarificar a correlação entre transtorno do déficit de atenção (TDAH) com epilepsia e problemas comportamentais. Este foi um estudo transversal. Sessenta crianças com epilepsia idiopática foram entrevistadas com a Escala para Pais e Professores MTA-SNAP IV, Escala de Comportamento Adaptativo Vineland e Escala Conners. Utilizamos o teste do qui-quadrado para analisar a correlação das variáveis de epilepsia em pacientes com e sem TDAH com um nível de significância de 0,05. Oito pacientes apresentaram sintomas de TDAH (13%), sete tiveram o subtipo inatento e três deles tinham problemas comportamentais. Quando os pacientes epilépticos com e sem TDAH foram comparados, não encontramos diferença significativa em relação às variáveis de epilepsia. Todos os pacientes estavam controlados e 43% deles estavam sem medicação ou em retirada da droga. O nosso estudo mostrou baixa comorbidade entre epilepsia e TDAH devido à baixa interferência de crises e tratamento na condição comórbida.

Our aim was to clarify the correlation of attention deficit hyperactivity disorder (ADHD) with epilepsy and behavior problems. This was a cross-sectional study. Sixty children with idiopathic epilepsy were interviewed using the MTA-SNAP IV Teacher and Parent Rating Scale, Vineland Adaptive Behavior Scales and Conners’ Rating Scales. We used the chi-square test to analyze the correlation of epilepsy variables in patients with and without ADHD with a significance level of 0.05. Eight patients had ADHD symptoms (13%), seven had the inattentive ADHD subtype and only three had behavioral problems. When epileptic patients with and without ADHD symptoms were compared we found no significant difference in regard to epilepsy variables. All patients were controlled and 43% were either without AED or undergoing withdrawal. Our study revealed a low comorbidity of ADHD symptoms and epilepsy due to low interference of seizures and drug treatment on the comorbid condition.

https://doi.org/10.1590/0004-282X20130193 3692 downloads

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