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Valoración de los factores de riesgo para la hipertensión arterial en adolescentes escolares
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Prieto-Peña, Ana Iris

; Molina-Estévez, Mirian Luisa

; Sánchez-Hernández, Daylis

; García-Prieto, Harold

Revista Médica Electrónica

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oct 2021, Volume 43 N. 5 Pages 1371 - 1382

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: essential arterial hypertension of the adult has its onset in childhood. Objective: to assess the influence of risk factors of essential arterial hypertension in adolescents of the Antonio Rodríguez Secundary School, in the municipality of Colón, province of Matanzas. Materials and methods: analytical study (prospective cohort observational) that constitutes a cut of the project "Prevention and control of hypertension in adolescents," of the Teaching Policlinic Dr. Carlos J. Finlay, in the period February to June 2016. Intentional non-probabilistic sampling, by criteria that included those 7th grade students who accepted, like their parents, to participate in the study. They were interviewed, measured, and had blood pressure measured. Sample: 160 teenagers. Variables: sex, body mass index, sedentarism, diabetes mellitus, smoking, alcohol intake, excessive salt intake, inadequate eating habits, low birth weight, maintained stress and family pathological history of hypertension. The SPSS 21 statistical package was used. Chi squared statistical test with µ = 0.05. Results: statistical significance was evidenced in innapropriate eating habits, family history of arterial hypertension, sedentarism and body mass index ≥ 25 in the onset of hypertension. 9 adolescents were identified without risk factors, all of them with normal arterial tension. 61,1 % showed three or more factors, including 100 % of the diagnosed hypertensives (5), and 17 prehypertensive ones (54,4 %). Conclusions: unhealthy ways and lifestyles and the presence of three or more risk factors were relevant in students high blood pressure.

RESUMEN Introducción: la hipertensión arterial esencial del adulto tiene sus inicios desde la niñez. Objetivo: valorar la influencia de factores de riesgo de hipertensión arterial esencial en adolescentes de la Escuela Secundaria Básica Antonio Rodríguez, del municipio Colón, provincia de Matanzas. Materiales y métodos: estudio analítico (observacional de cohorte prospectivo) que constituye un corte del proyecto “Prevención y control de la hipertensión arterial en adolescentes”, del Policlínico Docente Dr. Carlos J. Finlay, en el período de febrero a junio de 2016. Muestreo no probabilístico intencional, por criterios que incluyeron a aquellos estudiantes de 7mo grado que aceptaron, al igual que sus padres, la participación en el estudio. Se entrevistaron, mensuraron y se les midió la tensión arterial. Muestra: 160 adolescentes. Variables: sexo, índice de masa corporal, sedentarismo, diabetes mellitus, tabaquismo, ingestión de alcohol, ingestión excesiva de sal, hábitos alimentarios inadecuados, bajo peso al nacer, estrés mantenido y antecedentes patológicos familiares de hipertensión. Se utilizó el paquete estadístico SPSS 21. Test estadístico de Chi cuadrado con un µ = 0,05. Resultados: se evidenció significación estadística en los hábitos alimentarios no adecuados, antecedentes patológicos familiares de hipertensión arterial, sedentarismo e índice de masa corporal ≥ 25 en la aparición de hipertensión. Se identificaron 9 adolescentes sin factores de riesgo, todos con presión arterial normal. Con tres o más factores el 61,1 %, entre ellos el 100 % de los hipertensos diagnosticados (5) y 17 prehipertensos (54,4 %). Conclusiones: los modos y estilos de vida poco saludables y la presencia de tres o más factores de riesgo, fueron relevantes en los estudiantes con presión arterial elevada.

Mental health, family roles and employment status inside and outside the household in Spain
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Torre, Jorge Arias-de la

; Molina, Antonio J.

; Fernández-Villa, Tania

; Artazcoz, Lucía

; Martín, Vicente

Gaceta Sanitaria

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jun 2019, Volume 33 N. 3 Pages 235 - 241

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Objective To document the prevalence of poor mental health by gender and social class, and to analyze if poor mental health is associated with the family roles or the employment status inside and outside the household. Method A cross-sectional study based on a representative sample of the Spanish population was carried out (n = 14,247). Mental health was evaluated using GHQ-12. Employment status, marital status, family roles (main breadwinner and the person who mainly carries out the household work) and educational level were considered as explanatory variables. Multiple logistic regression models stratified by gender and social class were fitted and adjusted odds ratios (aOR) were obtained. Results Gender and social class differences in the prevalence of poor mental health were observed. Unemployment was associated with higher prevalence. Among men the main breadwinner role was related to poor mental health mainly in those that belong to manual classes (aOR = 1.2). Among women, mainly among nonmanual classes, these problems were associated to marital status: widowed, separated or divorced (aOR = 1.9) and to dealing with the household work by themselves (aOR = 1.9). Conclusions In Spain, gender and social class differences in mental health still exist. In addition, family roles and working situation, both inside and outside the household, could constitute a source of inequalities in mental health.

RESUMEN Objetivo Conocer la prevalencia de mala salud mental por sexo y clase social, y analizar si la salud mental se relaciona con los roles familiares y la situación laboral fuera y dentro del hogar. Método Se realizó un diseño transversal basado en una muestra representativa de la población española (n = 14.247). La salud mental se evaluó mediante el GHQ-12. Se consideraron como variables explicativas la situación laboral, el estado civil, el rol familiar (sustentador principal y persona que realiza el trabajo doméstico) y el nivel de estudios. Se ajustaron modelos de regresión logística estratificados por sexo y se obtuvieron las odds ratio ajustadas (ORa). Resultados Se observaron diferencias en la prevalencia de mala salud mental por sexo y clase social. El desempleo se asoció con mayor prevalencia. En hombres pertenecientes a clases menos favorecidas, el rol de sustentador principal se relacionó con mala salud mental (Ora = 1,2) En mujeres que pertenecían a clases más favorecidas, el estado civil viuda, separada o divorciada (ORa = 1,9) y realizar el trabajo doméstico solas (ORa = 1,9) se relacionaron con mala salud mental. Conclusiones En España, en salud mental continúa habiendo diferencias de sexo y clase social. Además, el rol familiar y la situación laboral fuera y dentro del ámbito doméstico podrían constituir también una fuente de desigualdad en salud mental.

https://doi.org/10.1016/j.gaceta.2017.11.005 220 downloads

Mental health, family roles and employment status inside and outside the household in Spain
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Torre, Jorge Arias-de la

; Molina, Antonio J.

; Fernández-Villa, Tania

; Artazcoz, Lucía

; Martín, Vicente

Gaceta Sanitaria

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jun 2019, Volume 33 N. 3 Pages 235 - 241

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

https://doi.org/10.1016/j.gaceta.2017.11.005

Efecto de los antimaláricos sobre los diferentes dominios del índice de daño SLICC en pacientes de la cohorte GLADEL
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Pons-Estel, Guillermo J.

; Quintana, Rosana

; Wojdyla, Daniel

; Alarcón, Graciela S.

; Serrano, Rosa María

; Ugarte-Gil, Manuel

; Pimentel-Quiroz, Víctor

; Soriano, Enrique R.

; Catoggio, Luis J.

; Scolnik, Marina

; Sacnun, Mónica

; Saurit, Verónica

; Caeiro, Francisco

; Alvarellos, Alejandro

; Sarano, Judith

; García, Mercedes

; Onetti, Laura

; Drenkard, Cristina

; Berbotto, Guillermo

; Scherbarth, Hugo R.

; Sato, Emilia

; Bonfa, Eloisa

; Ferreira Borba, Eduardo

; Costallat, Lilian

; Xavier, Ricardo

; Tavares Brenol, Joao C.

; Da Silva, Nilzio A.

; Cavalcanti, Fernando

; Massardo, Loreto

; Jacobelli, Sergio

; Neira, Oscar

; Molina, José F

; Vásquez, Gloria

; Gómez-Puerta, José A.

; Alonso Gonzalez, Luis

; Iglesias Gamarra, Antonio

; Guibert-Toledano, Marlene

; Reyes, Gil A.

; Cardiel, Mario H.

; Pascual-Ramos, Virginia

; García de la Torre, Ignacio

; Barile, Leonor

; Silveira, Luis H.

; Amigo, Mary-Carmen

; Sauza del Pozo, María Josefina

; Acevedo-Vásquez, Eduardo M.

; Alfaro-Lozano, José

; Segami, María Inés

; Chacón-Díaz, Rosa

; Abadi, Isaac

; Esteva Spinetti, María H

; Pons-Estel, Bernardo A.

Revista argentina de reumatología

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sep 2018, Volume 29 N. 3 Pages 6 - 10

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objective: To assess the effects of antimalarials (AM) over the items of the SLICC Damage Index (SDI). Methods: Patients with recent (≤2 years) diagnosis of systemic lupus erythematosus (SLE) from the GLADEL cohort were studied. End-point: increase in items SDI since cohort entry. Independent variables (socio-demographic, clinical, laboratory and treatment) were included. The effect of AM as a time dependent variable on most frequent SDI items (adjusting for potential confounders) was examined with a multivariable Cox regression model. Results: Of the 1466 patients included in this analysis, 1049 (72%) received AM with a median exposure time of 30 months (Q1-Q3: 11-57). Damage occurred in 665 (45%) patients during a median follow-up time of 24 months (Q1-Q3: 8-55). There were 301 integument, 208 renal, 149 neuropsychiatric, 98 musculoskeletal, 88 cardiovascular and 230 others less frequently represented damages. After adjusting for potential confounders at any time during follow-up, a lower risk of renal damage (HR 0.652; 95% CI: 0.472-0.901) and borderline for neuropsychiatric damage (HR 0.701, 95% CI: 0.481-1.024) was found. Conclusion: In the GLADEL cohort, after adjustment for possible confounding factors, AM were independently associated with a reduced risk of renal damage accrual.

Objetivos: Estimar el efecto de los antimaláricos (AM) sobre los diferentes dominios del índice de daño SLICC (SDI). Métodos: Se estudiaron pacientes con diagnóstico clínico reciente (≤2 años) de lupus eritematoso sistémico (LES) de la cohorte GLADEL. Variable de estudio: aumento en los dominios del SDI desde el ingreso a la cohorte. Variables independientes: características sociodemográficas, clínicas, laboratorio y tratamientos. El efecto de los AM, como variable dependiente del tiempo, sobre los dominios más frecuentes del SDI (ajustado por factores de confusión) fue examinado con un modelo de regresión de Cox multivariado. Resultados: De 1466 pacientes estudiados, 1049 (72%) recibieron AM con un tiempo medio de exposición de 30 meses (Q1-Q3: 11-57) y 665 pacientes (45%) presentaron daño durante un seguimiento medio de 24 meses (Q1-Q3: 8-55); 301 eventos fueron cutáneos, 208 renales, 149 neuropsiquiátricos, 98 musculoesqueléticos, 88 cardiovasculares y 230 otros. Después de ajustar por factores de confusión, el uso de AM se asoció a un menor riesgo de daño renal (HR 0,652; IC 95%: 0,472-0,901) y en el límite de la significancia estadística (HR 0,701, IC 95%: 0,481-1,024) para el dominio neuropsiquiátrico. Conclusión: En GLADEL, el uso de AM se asoció independientemente a un menor riesgo de daño acumulado renal.

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Genetic diversity within wild species of Solanum
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Flores-Hernández, Luis Antonio

; Lobato-Ortiz, Ricardo

; Sangerman-Jarquín, Dora María

; García-Zavala, J. Jesús

; Molina-Galán, José D.

; Velasco-Alvarado, Mario de Jesús

; Marín-Montes, Iván Maryn

Revista Chapingo. Serie horticultura

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aug 2018, Volume 24 N. 2 Pages 85 - 96

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Cultivated tomato (Solanum lycopersicum L.) has undergone a reduction in its genetic base as a result of the processes of modern domestication and breeding, which has been extensively documented by molecular markers in different genotypes, both nationally and internationally. Faced with this situation, some plant breeders in Mexico have proposed making use of native Mexican germplasm, as well as of the genetic variation present in wild species related to the cultivated tomato. The aim of this study was to characterize agronomically, under greenhouse conditions, accessions of five wild relatives of the cultivated tomato for their incorporation into breeding programs of this vegetable. In addition, it is expected to reduce its vulnerability to climate change and adverse biotic and abiotic factors. The species described were Solanum pennellii L., Solanum pimpinellifollium L., Solanum peruvianum L., Solanum chilense R. and Solanum habrochaites S. The accessions were evaluated under greenhouse conditions under a completely randomized experimental design with four replications. Twelve traits of agronomic interest were evaluated to describe the variation between the accessions of each one of the evaluated species, which were studied by analysis of variance and comparison of means. The results showed high significance among the accessions of each one of the evaluated species for all the traits. The above shows that there is a high potential in each of the accessions of the species studied to exploit them genetically in the improvement of the cultivated tomato.

Resumen El jitomate (Solanum lycopersicum L.) ha sufrido reducción de su base genética durante los procesos de domesticación y mejoramiento genético moderno, lo que ha sido documentado ampliamente mediante marcadores moleculares en diferentes genotipos, tanto a nivel nacional como internacional. Ante esta situación, en México algunos fitomejoradores han planteado hacer uso de germoplasma nativo mexicano, así como de la variación genética presente en especies silvestres emparentadas con el jitomate cultivado. El objetivo del presente trabajo fue caracterizar agronómicamente, en condiciones de invernadero, accesiones de cinco parientes silvestres del jitomate para su incorporación en programas de mejoramiento genético de esta hortaliza. Además, con ello se espera reducir su vulnerabilidad frente al cambio climático y a factores bióticos y abióticos adversos. Las especies descritas fueron Solanum pennellii L., Solanum pimpinellifollium L., Solanum peruvianum L., Solanum chilense R. y Solanum habrochaites S. Las accesiones se evaluaron en condiciones de invernadero bajo un diseño experimental completamente al azar con cuatro repeticiones. Se evaluaron 12 variables de interés agronómico para describir la variación existente entre las accesiones de cada una de las especies evaluadas, las cuales se estudiaron mediante análisis de varianza y comparación de medias. Los resultados mostraron alta significancia entre las accesiones de cada una de las especies evaluadas para todas las variables. Lo anterior demuestra que existe un elevado potencial en cada una de las accesiones de las especies estudiadas para aprovecharlas genéticamente en el mejoramiento del jitomate cultivado.

https://doi.org/10.5154/r.rchsh.2017.08.030 978 downloads

REFORMA UNIVERSITARIA: Manifiesto Liminar
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Barros, Enrique F.

; Valdés, Horacio

; Bordabehere, Ismael C.

; Sayago, Gurmensindo

; Castellanos, Alfredo

; Méndez, Luis M.

; Bazante, Jorge L.

; Garzón Maceda, Ceferino

; Molina, Julio

; Suárez Pinto, Carlos

; Biagosch, Emilio R.

; Nigro, Angel J.

; Saibene, Natalio J.

; Medina Allende, Antonio

; Garzón, Ernesto

Praxis educativa

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jan 2018, Volume 22 N. 1 Pages 95 - 98

Abstract: Es | Text: Es | PDF: Es

78 downloads

Psychometric properties of the Spanish version of the 12-item Interpersonal Needs Questionnaire in fibromyalgia syndrome patients
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Ordoñez-Carrasco, Jorge L.

; Salgueiro, Monika

; Sayans-Jiménez, Pablo

; Blanc-Molina, Andrea

; García-Leiva, Juan Miguel

; Calandre, Elena P.

; Rojas, Antonio J.

Anales de Psicología

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2018, Volume 34 N. 2 Pages 273 - 281

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract According to the interpersonal theory of suicide, thwarted belongingness and perceived burdensomeness are key elements in the development of suicidal ideation. The Interpersonal Needs Questionnaire (INQ) was developed to assess the degree of frustration of these two interpersonal needs related to suicidal ideation. This study aims to analyze the psychometrics properties of a Spanish adaptation of INQ-12 in fibromyalgia patients. Exploratory factor analysis (n = 180) and confirmatory factor analysis (n = 179) were performed in two randomly selected sub-samples. The first analysis leads to the elimination of two items, whereas the second one confirmed the fit of the proposed two-factor structure. The reliability estimated using the Cronbach´s alpha coefficient and the Spearman-Brown coefficient was adequate. To obtain further validity evidence based on the relationship with other variables three variables were used. Moreover, a control group (n = 99) was used to contrast the means of INQ scores as evidence of validity based on differential scores. These findings support the usefulness of the Spanish version of the INQ-10 for assessing the degree of frustration of these interpersonal needs in patients with fibromyalgia.

Resumen Según la teoría interpersonal del suicidio, la pertenencia frustrada y la carga percibida son elementos clave en el desarrollo de la ideación suicida. El Cuestionario de necesidades interpersonales (INQ) fue diseñado para evaluar el grado de frustración de estas dos necesidades interpersonales relacionadas con la ideación suicida. El objetivo de este estudio fue analizar las propiedades psicométricas de una adaptación al español del INQ-12 en pacientes con fibromialgia. Un análisis factorial exploratorio (n = 180) y un análisis factorial confirmatorio (n = 179) fueron realizados en dos submuestras seleccionadas al azar. El primer análisis llevó a la eliminación de dos ítems, mientras que el segundo confirmó el ajuste de la estructura propuesta de dos factores. La fiabilidad estimada mediante el coeficiente alfa de Cronbach y el coeficiente Spearman-Brown fue adecuada. Para obtener evidencias de validez basadas en la relación con otros variables, se utilizaron tres variables relacionadas con el suicidio. Además, se utilizó un grupo control (n = 99) para contrastar los promedios de las puntuaciones INQ como evidencia de validez basada en puntajes diferenciales. Estos hallazgos respaldan la utilidad de la versión española del INQ-10 para evaluar el grado de frustración de estas necesidades interpersonales en pacientes con fibromialgia.

https://doi.org/10.6018/analesps.34.2.293101 584 downloads

Declaración de Sant Joan d'Alacant en defensa del Acceso Abierto a las publicaciones científicas, del grupo de editores de revistas españolas sobre ciencias de la salud (GERECS)
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Sanz-Valero, Javier

; Melero Melero, Remedios

; Bojo Canales, Cristina

; Perdiguero Gil, Enrique

; Culebras Fernández, Jesús Manuel

; Wanden-Berghe, Carmina

; Ruiz López, María Dolores

; Amezcua Martínez, Manuel

; Alvarez-Dardet, Carlos

; Astrain Gallart, Mikel

; Vaquero Pérez, María del Mar

; López Montesinos, María José

; Sosa Henríquez, Manuel

; Pardal-Refoyo, José Luis

; Romero Medina, Agustín

; Primo Peña, Elena

; Hernández Merino, Ángel

; Torres Morera, Luis Miguel

; Bascones Martínez, Antonio

; Fernández Llimos, Fernando

; Rodríguez Portillo, Mariano

; Soldevilla Agreda, J. Javier

; Soriano el Castillo, José Miguel

; Ronda Pérez, Elena

; Rodríguez Álvaro, Martín

; Moreno Villares, José Manuel

; del Campo Balsa, Teresa

; Molina Olivas, Marta

; Almaraz Carretero, Julián

; Abadal, Ernest

; Crespo Montero, Rodolfo

; Dago Martínez, Ana

Enfermería Nefrológica

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dec 2017, Volume 20 N. 4 Pages 291 - 293

Abstract: Es | Text: Es | PDF: Es

https://doi.org/10.4321/s2254-28842017000400002 162 downloads

Declaración de Sant Joan d'Alacant en defensa del acceso abierto a las publicaciones científicas, del grupo de editores de revistas españolas sobre ciencias de la salud (GERECS)
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Sanz-Valero, Javier

; Melero Melero, Remedios

; Bojo Canales, Cristina

; Perdiguero Gil, Enrique

; Culebras Fernández, Jesús Manuel

; Wanden-Berghe, Carmina

; Ruiz López, Maria Dolores

; Amezcua Martínez, Manuel

; Alvarez-Dardet, Carlos

; Astrain Gallart, Mikel

; Vaquero Pérez, María del Mar

; López Montesinos, María José

; Sosa Henríquez, Manuel

; Pardal-Refoyo, José Luis

; Romero Medina, Agustín

; Primo Peña, Elena

; Hernández Merino, Ángel

; Torres Morera, Luis Miguel

; Bascones Martínez, Antonio

; Fernandez-Llimos, Fernando

; Rodríguez Portillo, Mariano

; Soldevilla Agreda, J. Javier

; Soriano del Castillo, José Miguel

; Ronda Pérez, Elena

; Rodríguez Álvaro, Martín

; Moreno Villares, Jose Manuel

; del Campo Balsa, Teresa

; Molina Olivas, Marta

; Almaraz Carretero, Julián

; Abadal, Ernest

; Crespo Montero, Rodolfo

; Dago Martínez, Ana

Cuadernos de Medicina Forense

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dec 2017, Volume 23 N. 3-4 Pages 112 - 114

Abstract: Es | Text: Es | PDF: Es

203 downloads

10.

Efficacy of an internal teat seal associated with a dry cow intramammary antibiotic for prevention of intramammary infections in dairy cows during the dry and early lactation periods
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Molina, Lívio R.

; Costa, Hudson. N.

; Leão, Juliana M.

; Malacco, Victor M.R.

; Facury Filho, Elias J.

; Carvalho, Antônio U.

; Lage, Camila F.A.

Pesquisa Veterinária Brasileira

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may 2017, Volume 37 N. 5 Pages 465 - 470

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Objetivou-se avaliar o uso de um selante interno de tetos contendo subnitrato de bismuto (Teatseal®, Zoetis®, Florham Park, Nova Jersey, EUA) associado a um antibiótico de longa ação contendo cloxacilina (Orbenin® Extra dry cow, Zoetis®, Florham Park, Nova Jersey, EUA) em prevenir novas infecções durante o período seco e pós-parto imediato. Foram utilizadas 150 vacas Holandesas (produção média de 9,000 kg de leite por lactação), com os quatro quartos mamários funcionais e sem mastite clínica, que foram secas 60 dias antes da data prevista para o parto. O teto constituiu a unidade experimental. O grupo controle (C) foi representado por dois tetos diagonais-contralaterais (n=300), que receberam somente o antibiótico de vaca seca. Os outros dois tetos (n=300) constituíam o grupo tratado (T) e recebiam o antibiótico de vaca seca associado ao selante interno. Dados da variável contagem de células somáticas (CCS) passaram por transformação logarítmica na base 10 e foram submetidos ao teste de Duncan, aceitando-se nível de 5% de significância estatística. A ocorrência de infecções intramamárias (IIM), taxa de cronicidade e frequência de microrganismos isolados na secagem e imediatamente pós-parto nos tetos do grupo controle e tratados com selante interno foram avaliados utilizando o teste não paramétrico qui-quadrado, aceitando 10% de nível de significância. Houve redução na ocorrência de novas infecções no pós-parto imediato nos animais em que se utilizou o selante (C=19,6%, T=11,4%). No período pós-parto, foram isolados microrganismos Gram-negativo de 16 tetos no C e sete no T. A maior redução ocorreu para Escherichia coli, (8 versus 1) no grupo T. Não houve efeito da utilização do selante interno na frequência de isolamento de Streptococcus ambientais. O uso do selante reduziu a prevalência de mastite subclínica das vacas no pós-parto imediato (C=51% versus T=42%) e resultou em menor CCS no grupo tratado (T = 1.073 x 103) quando comparado com o grupo controle (C=1.793x103). O uso do selante interno combinado com antibiótico de vacas secas é eficaz na prevenção de infecções intramamárias no período seco e início de lactação e resulta na redução da CCS no período pós-parto imediato. O tratamento é eficaz na redução de infecção entre a secagem e o pós-parto imediato causada por patógenos maiores e menores. Entretanto, não tem efeito sobre infecções causadas por patógenos contagiosos.

ABSTRACT: The present study aimed to evaluate the use of an internal dry period teat seal containing bismuth subnitrate (Teatseal®, Zoetis®, Florham Park, Nova Jersey, USA) associated with a long-acting cloxacilin preparation (Orbenin® Extra dry cow, Zoetis®, Florham Park, Nova Jersey, USA), in preventing new infections during the dry-off and early postpartum period. A total of 150 Holstein cows (average production of 9,000 kg of milk per lactation), with four functional udder quarters without clinical mastitis was included in the study. All animals were dried-off 60 days before the expected calving date. Two teats positioned diagonal-contralaterally received only dry cow antibiotic, control group C (n=300) and the other two teats, treatment group T (n=300) received dry cow antibiotic and infusion with an internal teat seal. Data from SCC variable were transformed by log base-10 transformation. Duncan’s test was used accepting 5% as the level of statistical significance. The occurrence of intramammary infection (IMI) and chronicity rate, and frequency of microorganisms isolated at drying and immediately postpartum in teats of group C and group T were evaluated using a non-parametric Chi-square Test, accepting 10% as the statistical significance level. There was a decrease in the occurrence of new infections in the early postpartum in cows which the sealant was used (C=19.6%, T=11.4%). In the postpartum period, Gram-negative bacteria were isolated from 16 teats in C and seven in T. The greatest reduction was observed for Escherichia coli (8 vs 1) in group T. There was no effect using the internal sealant on the frequency of isolation of environmental Streptococus. The use of sealant reduced the prevalence of subclinical mastitis cows between drying-off and the early postpartum period (C=51% versus T=42%) and resulted in a lower somatic cell count (SCC) in the treatment group when compared with the control group (T=1,073x103, C=1,793x103). The use of the internal teat seal combined with dry cow antibiotic is effective in the prevention of IMI during the dry period and early lactation and results in the reduction of SCC in immediate postpartum period. The treatment is effective in reducing infection between dry-off and the immediate postpartum caused by major and minor pathogens. However, no effect on infections caused by contagious pathogens was observed.

https://doi.org/10.1590/s0100-736x2017000500007 1895 downloads

11.

Perfil mineral de vacas mestiças Girolanda no período de transição em sistema semi-intensivo em duas estações do ano
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Moreira, Tiago F.

; Zambrano, Jose U.

; Paula, Vitor M. de

; Casagrande, Fernando P.

; Facury Filho, Elias J.

; Molina, Lívio R.

; Leme, Fabíola O.P.

; Carvalho, Antônio U.

Pesquisa Veterinária Brasileira

Journal Metrics
- Sobre o periódico
- SciELO Analytics

mar 2015, Volume 35 N. 3 Pages 249 - 257

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Neste estudo foi avaliado o perfil metabólico de vacas leiteiras no período de transição durante o verão e o inverno. Foram utilizados 31 animais pluríparos mestiços girolando em cada estação, totalizando 62 vacas. No verão permaneciam em pasto com suplementação de silagem de milho e concentrado. No inverno, a exigência nutricional era suprida apenas com silagem de milho e concentrado. Foram feitas um total de 11 coletas de sangue de cada animal segundo o seguinte protocolo: quatro coletas pré-parto espaçadas semanalmente, no dia do parto e com 2, 5, 10, 15, 21 e 30 dias pós-parto. Foram avaliadas as concentrações de cálcio, fósforo e magnésio. Todos os analitos variaram em função do estatus fisiológico. As concentrações médias de cálcio e magnésio foram maiores no verão do que no inverno. Em ambas as estações, as menores concentrações médias de cálcio ocorreram próximas ao parto, sendo que 75% dos animais no inverno e 35,48% dos animais no verão estavam hipocalcêmicos. Apenas no décimo dia as concentrações de cálcio voltaram aos níveis do pré-parto, demonstrando que esse tempo é necessário para a adaptação da nova condição de lactante. As concentrações de magnésio foram menores no pós-parto do que no pré-parto nas duas estações, demonstrando a necessidade desse mineral para a produção de leite. As concentrações médias de magnésio permaneceram sempre dentro dos valores de referência, porém 19% dos animais aos dois dias pós-parto no inverno e 7% dos animais aos 10 dias pós-parto no verão tinham concentrações inferiores a esses limites. As concentrações de fósforo sofreram grande variação ao longo do peri-parto, porém sempre em níveis elevados, sendo que 49,8% dos animais no inverno e 37,3% no verão tinham níveis de fósforo acima dos valores de referência

The metabolic profile of dairy cows in the transition period during summer and winter was evaluated. Were used 31 crossbred Holstein/Gir cows at each season, totaling 62 cows. During summer they remained in pasture with supplementation of corn silage and concentrate and in the winter, corn silage and concentrate was offered to furnish the nutritional requirements. A total of 11 blood samples from each animal were taken according to the following protocol: four collections weekly antepartum, at birth and at 2, 5, 10, 15, 21 and 30 days postpartum. Concentrations of calcium, phosphorus and magnesium were evaluated. All analytes varied according to the physiological status. The average concentrations of calcium and magnesium were higher in summer than in winter. In both seasons, the lowest mean calcium concentrations occurred near calving, and 75% of the animals in winter and 35.48% of the animals in the summer were hypocalcemic. Only on the tenth day postpartum, the calcium concentrations returned to levels of prepartum, demonstrating that this time is necessary for the adaptation of the new condition of lactating. Magnesium concentrations were lower postpartum than prepartum in both seasons, demonstrating the need for this mineral for the production of milk. The average concentrations of magnesium remained always within the reference values for the species, but 19% of the animals at two days postpartum in winter and 7% of the animals at 10 days postpartum in summer had concentrations below these limits. Phosphorus concentrations suffered large variation along the peri-partum, but always at high levels, with 49.8% of the animals in winter and 37.3% in summer had phosphorus levels above the reference range of the species.

https://doi.org/10.1590/S0100-736X2015000300007 2123 downloads

12.

Avaliação do perfil metabólico de vacas da raça Holandesa durante o período de transição
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Alvarenga, Emerson A.

; Moreira, Gustavo H.F.A.

; Facury Filho, Elias J.

; Leme, Fabíola O.P.

; Coelho, Sandra G.

; Molina, Lívio R.

; Lima, Juliana A.M.

; Carvalho, Antônio U.

Pesquisa Veterinária Brasileira

Journal Metrics
- Sobre o periódico
- SciELO Analytics

mar 2015, Volume 35 N. 3 Pages 281 - 290

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O período de transição é um momento de grande desafio para vacas de aptidão leiteira, uma vez que, a maioria dos problemas metabólicos ocorre nesta fase podendo prejudicar toda a expectativa de produção durante a lactação, resultando em impacto econômico significativo para fazendas de produção de leite. Este trabalho teve como objetivo avaliar o perfil metabólico de vacas da raça Holandesa durante o período de transição. Doze vacas Holandesas foram avaliadas, três semanas pré-parto até três semanas pós-parto, em sistema free-stall, localizado em Inhaúma, Minas Gerais, no período de outubro a dezembro de 2012. Avaliou-se o perfil metabólico através da concentração sérica de ácidos graxos não esterificados (AGNE), beta hidroxibutirato (BHBA), colesterol (COLES), proteína total (PT), albumina (ALB), cálcio, fósforo, magnésio bem como a atividade sérica das enzimas aspartato transaminase (AST) e lactato desidrogenase (LDH). As concentrações séricas de AGNE e BHBA foram diferentes entre o pré-parto e pós-parto (p<0,05). Observou-se diminuição na concentração de COLES com a aproximação do parto com posterior aumento (p<0,05). As concentrações séricas dos minerais, PT e ALB não apresentaram diferenças (p>0,05) no período avaliado. A atividade enzimática de AST e LDH foram maiores no período pós-parto (p<0,05). A avaliação do perfil metabólico é uma importante ferramenta de monitoramento e, na situação estudada, demonstrou alterações do perfil energético das vacas entre os períodos pré e pós-parto, relacionadas provavelmente a diminuição da ingestão de alimentos. A luz dos resultados do perfil metabólico, o rebanho avaliado possui pequeno risco para a ocorrência de enfermidades no pós-parto relacionadas ao período de transição

The transition period is a time of great challenge for dairy cows, since most metabolic problems occur at this time and can compromise the entire lactation, resulting in a significant economic loss to commercial farms. This study evaluated the metabolic profile of dairy cows during the transition period. Twelve Holstein cows between three weeks pre-calving until three weeks postpartum was used in this study. They remained in a free-stall system, located in Inhaúma, Minas Gerais, during October to December 2012. The metabolic profile were composed by non-esterified fatty acids (NEFA), beta-hydroxybutyrate (BHBA), cholesterol (COLES), total protein (TP), albumin (ALB), calcium, phosphorus, magnesium as well as the activity serum enzymes aspartate transaminase (AST) and lactate dehydrogenase (LDH). There were differences in serum NEFA and BHBA between prepartum and postpartum (p<0.05). Observed a decrease in the concentration of COLES with the approaching birth with subsequent increase (p<0.05). Serum concentrations of minerals, PT and ALB did not differ (p>0.05). The enzymatic activity of AST and LDH were higher in the postpartum period (p<0.05). The evaluation of the metabolic profile is an important monitoring tool. Changes in the metabolic profile of cows during the transition period are motivated by energetic changing. Cows that were evaluated have a small risk of developing postpartum diseases related to the transition period

https://doi.org/10.1590/S0100-736X2015000300012 4380 downloads

13.

Maternal fat mass may predict overweight/obesity in non-instituzionalized women with intellectual disability
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Fornieles, Gabriel

; Camacho-Molina, Alejandra

; Rosety, Miguel A.

; Díaz, Antonio J.

; Rosety, Ignacio

; Rosety-Rodríguez, Manuel

; Alvero-Cruz, José Ramón

; Rosety, Manuel

; Ordonez, Francisco J.

Nutrición Hospitalaria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2013, Volume 28 N. 6 Pages 1918 - 1921

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Introduction: Previous studies have found a significant correlation between parents and offspring regarding overweight and obesity in general population at early life stages. However this issue has received no attention in people with intellectual disability (ID). Therefore, the present study was designed to find out potential correlations in overweight/obesity between young adult women with ID living in the family and their parents. Material and methods: In the present observational cross-sectional study, a total of thirty-four women with Down syndrome (n = 34; 22.6 ± 2.1 years; 29.6 ± 3.3 km/m²) were recruited through different community support groups for people with intellectual disabilities. Furthermore, biological mothers (n = 34; 59.6 ± 4.9 years; 28.5 ± 3.2 km/m²) and fathers (n = 34; 61.5 ± 5.3 years; 26.2 ± 2.7 km/m²) volunteered for this study. They all underwent an anthropometric assessment to determine body mass index (BMI). This protocol was approved by an Institutional Ethics Committee. Results: In the studied population, a total of 26 (76.5%) women with ID were overweight/obese. Furthermore, there were 22 (66.6%) overweight/obese mothers and 16(53.3%) fathers. Results also showed significant correlations between participants BMI and their father (r = 0.327; p = 0.0116) and mother BMI (r = 0.412; p < 0.001). Lastly, overweight/obese women presented a stronger correlation with overweight/obese mothers (odds ratio 4.3; 95%CI 2.9-7.3) than fathers (odds ratio 3.1; 95%CI 1.6-4.4). Conclusion: Parental overweight/obesity, especially maternal one, was strongly associated to overweight/obesity in young adult women with DS. Accordingly, there is an urgent necessity of incorporating parents in the intervention programs designed to the prevention and treatment of overweight and obesity in people with ID.

Fundamento y objetivo: Recientes estudios han encontrado en la población general una correlación entre la incidencia de sobrepeso/obesidad de padres e hijos, especialmente a edades tempranas. Sin embargo, este asunto no ha recibido atención en el caso de hijos adultos con discapacidad intelectual no institucionalizados. El presente estudio pretende determinar una posible correlación entre el sobrepeso/obesidad de padres respecto a sus hijas adultas con discapacidad intelectual que viven en el domicilio. Material y método: Se diseñó un estudio de tipo transversal observacional en el que participaron 34 mujeres adultas con síndrome de Down (22,6 ± 2,1 años; 29,6 ± 3,3 km/m²). Asimismo 34 madres (59,6 ± 4,9 años; 28,5 ± 3,2 km/m2) y 34 padres (61,5 ± 5,3 años; 26,2 ± 2,7 km/m²) biológicos participaron voluntariamente. Todos los participante se sometieron a un estudio cinenatropométrico en el que se obtuvo el índice de masa corporal (IMC). Este protocolo fue aprobado por un Comité de Ética Institucional. Resultados: El 76,5% de las mujeres con discapacidad intelectual estudiadas presentaba sobrepeso/obesidad. En cuanto a los progenitores, el 66,6% de las madres y el 53.3 de los padres también presentó sobrepeso/obesidad. El IMC de las participantes se correlacionó significativamente con el de sus madres (r = 0,412; p < 0,001) y padres (r = 0,327; p = 0,0116). Por último, las participantes con sobrepeso/obesidad presentaron una fuerte correlación con sus progenitores con sobrepeso/obesidad, especialmente las madres (odds ratio 4,3; 95%CI 2,9-7,3) y en menor medida sus padres (odds ratio 3,1;95%CI 1,6-4,4). Conclusión: La masa grasa de los padres, especialmente la materna, podría recomendarse como predictor de sobrepeso/obesidad de hijas adultas con discapacidad intelectual no institucionalizadas.

https://doi.org/10.3305/nh.2013.28.6.6967 327 downloads

14.

Central obesity measurements predict metabolic syndrome in a retrospective cohort study of postmenopausal women
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Rosety-Rodríguez, Manuel

; Fornieles, Gabriel

; Rosety, Ignacio

; Díaz, Antonio J.

; Rosety, Miguel A.

; Camacho-Molina, Alejandra

; Rodríguez-Pareja, A.

; Tejerina, A.

; Alvero-Cruz, José Ramón

; Ordonez, Francisco J.

Nutrición Hospitalaria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

dec 2013, Volume 28 N. 6 Pages 1912 - 1917

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Introduction: The various diagnostic classifications in the literature concur as regards the important role of abdominal obesity in the onset and progression of metabolic syndrome. Accordingly, this study was aimed at clarifying whether central obesity measurements assessed by dual X-ray absorptiometry (DXA) may predict metabolic syndrome in Spanish postmenopausal women. Material and methods: This historical cohort study included a total of 1326 postmenopausal women aged > 45 years old who had routinely undergone DXA to measure their bone mineral density between january 2006 and january 2011. The regions of interest (ROI) envisaged in our study by using DXA were the lumbar regions L1-L4 and L4-L5. At the same time, they underwent a complete medical examination including personal medical history assessment, biochemical blood analysis, blood pressure measurement and anthropometrical evaluation. Metabolic syndrome was diagnosed attending to the criteria established by National Cholesterol Education Program Adult Treatment Panel III (NECP-ATP-III). Results: During the observation period, 537 women, representing 40.5% of the total studied, met the diagnostic criteria for metabolic syndrome. L1-L4 and L4-L5 abdominal fat mass determinations were associated with the development of metabolic syndrome in all regression models tested, showing an increasing gradient from the lowest to highest quintile. Conclusion: Central adiposity measurements assessed by DXA, especially L1-L4 region of interest, could be considered a powerful predictor of metabolic syndrome in postmenopausal women.

Introducción: En la actualidad se acepta la importancia de la masa grasa abdominal en la fisiopatología del síndrome metabólico tal y como reconocen las diferentes clasificaciones diagnósticas disponibles. Nuestro objetivo fue analizar la utilidad como predictores de síndrome metabólico de marcadores de grasa abdominal obtenidos por DEXA en mujeres postmenopausicas aprovechando su participación en screening rutinarios para el estudio de la densidad mineral ósea. Material y método: El presente estudio de cohortes histórico incluyó a un total de 1.326 mujeres post-menopausicas con edad > 45 años que se habían sometido rutinariamente a DEXA para conocer su densidad mineral ósea entre enero de 2006 y enero de 2011. Además del DEXA, se obtuvo de cada participante la correspondiente anamnesis, bioquímica, tensión arterial e índices de distribución de masa grasa mediante técnicas antropométricas convencionales. Se utilizó la clasificación NCEP-ATP-III para el diagnóstico de síndrome metabólico. Este protocolo fue aprobado por un Comité de Ética Institucional. Resultados: Durante el periodo de observación, 537 mujeres, el 40,5% del total de las estudiadas, cumplió los criterios diagnósticos de síndrome metabólico. Los parámetros de masa grasa abdominal obtenidos mediante DEXA fueron significativamente mayores en mujeres postmenopáusicas con síndrome metabólico. Finalmente, la masa grasa abdominal de regiones de interés L1-L4 y L3-L4 obtenidas por DEXA se relacionaron con el desarrollo de síndrome metabólico en los modelos de regresión ensayados. Conclusión: La masa grasa abdominal determinada por DEXA, especialmente la región L1-L4, podría recomendarse como predictor de síndrome metabólico en este grupo.

https://doi.org/10.3305/nh.2013.28.6.6911 325 downloads

15.

Reducción de reactantes de fase aguda en mujeres con síndrome metabólico tras 12 semanas de entrenamiento
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Rosety-Rodríguez, Manuel

; Fornieles, Gabriel

; Camacho-Molina, Alejandra

; Rosety, Ignacio

; Díaz, Antonio J.

; Rosety, Miguel A.

; Rodríguez-Pareja, Antonia

; Ordonez, Francisco J.

Nutrición Hospitalaria

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2013, Volume 28 N. 5 Pages 1604 - 1609

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Introduction: It is accepted low grade systemic inflammation plays a key role in metabolic syndrome. Further, several studies have reported it may be considered a therapeutic target. Accordingly, this study was conducted to ascertain the impact of a short-term aerobic training program on acute phase proteins in women with metabolic syndrome. Material and methods: A total of 135 adult women (38.4 ± 3.3 years) with metabolic syndrome volunteered for this study. Participants assigned to the intervention group underwent a 12-week aerobic training program, 3 sessions/week. The main part of each exercise sessions was performed in a treadmill at moderate intensity (60-75% HRmax; increasing 5% each 3 weeks) for 25-40 minutes (increasing 5 minutes each 3 weeks). Physical fitness was determined by a continuous maximal incremental test. Further, fat mass percentage and indices of obesity were assessed. Plasmatic levels of C reactive protein (CRP-us) and fibrinogen were determined by nephelometry and HPLC respectively. This protocol was approved by an Institutional Ethics Committee. Results: Aerobic training improved physical fitness and reduced both fat mass percentage and indices of obesity. Compared with baseline, it also reduced significantly plasmatic levels of CRP-us (4.90 ± 0.7 vs. 3.77 ± 0.4 mg/l; p = 0.017) and fibrinogen (3.88 ± 0.4 vs. 3.36 ± 0.2 g/l; p = 0.025). Further, a moderate correlation was found between CRP-us and waist circumference (r = 0.66; p = 0.008). No significant changes were found in controls. Conclusion: A short-term, aerobic training program reduced acute phase proteins in young women with metabolic syndrome. Further, long-term, well-conducted studies are still required to determine whether correction of this low-grade inflammation improves clinical outcomes of women with metabolic syndrome.

Fundamento y objetivo: Actualmente se acepta la importancia del estatus proinflamatorio en la fisiopatología del síndrome metabólico. De hecho, ha sido propuesto como diana terapéutica en el manejo clínico de estos pacientes. Por consiguiente este estudio pretende reducir los niveles plasmáticos de reactantes de fase aguda en mujeres con síndrome metabólico mediante un corto programa de entrenamiento. Material y método: Un total de 135 mujeres jóvenes adultas (38,4 ± 3,3 años) con diagnóstico de síndrome metabólico participaron voluntariamente en este estudio. El grupo de intervención se sometió a un programa de entrenamiento aeróbico de 12 semanas, con 3 sesiones/ semana en el que duración e intensidad de la parte principal se incrementaron progresivamente. Los niveles plasmáticos de proteína C-reactiva (PCR) y fibrinógeno se determinaron mediante nefelometría y HPLC respectivamente. También se evaluaron el fitness cardiovascular mediante prueba de esfuerzo máxima e índices de distribución de masa grasa. Este protocolo fue aprobado por un Comité de Ética Institucional. Resultados: Tras completar el programa, se observo una mejora significativa del fitness cardiovascular además de una reducción también significativa de los niveles de fibrinógeno y PCR. Asimismo, se encontraron correlaciones entre niveles de reactantes e índices de distribución de masa grasa, siendo la de mayor fuerza de asociación la establecida entre PCR y perímetro cintura. Conclusión: Un programa de 12 semanas consiguió reducir los niveles de reactantes de fase aguda en mujeres con síndrome metabólico. Futuros estudios longitudinales son necesarios para conocer el impacto del efecto anti-inflamatorio del ejercicio en el manejo de estos pacientes a medio/largo plazo.

https://doi.org/10.3305/nh.2013.28.5.6747 410 downloads

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