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Analysis of the status of treatment of benign thyroid diseases – a public health problem aggravated in the COVID-19 pandemic era
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Melo, Giulianno Molina

; Gonçalves, Antonio José

; Walder, Fernando

; Ferraz, Carolina

; Neves, Murilo Catafesta

; Abrahão, Marcio

; Cervantes, Onivaldo

Brazilian Journal of Otorhinolaryngology

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nov 2022, Volume 88 N. 6 Pages 982 - 989

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Bócios e nódulos benignos detectados na tireoide são lesões em crescimento e a pandemia de Covid-19 impactou negativamente seu tratamento cirúrgico. A seleção adequada de pacientes para o tratamento vai melhorar o estado geral de saúde. Esta revisão de artigos se concentrará no impacto da pandemia de Covid-19 no tratamento de condições benignas da glândula tireoide e suas implicações. Método: Esta revisão evidenciou a situação do sistema de saúde em países em desenvolvimento e os problemas para tratar doenças cirúrgicas benignas da tireoide. Aspectos da epidemiologia, incidência, apresentação clínica e tratamento cirúrgico do bócio, impacto econômico e no estado de saúde foram relatados. Resultados: Todos os tratamentos cirúrgicos de bócio e outras condições benignas foram adiados, forçados a se redirecionar e a remarcar todas as cirurgias benignas, situação agravada pela má gestão pública e fechamento de leitos hospitalares. Essas condições têm causado deterioração do estado de saúde física (doença da tireoide descompensada) e mental dos pacientes, aumentam as incapacidades para o trabalho e sobrecarregando a sociedade e o custo social e de saúde. A situação geral pode ser catastrófica em países emergentes, onde esse aumento dos gastos sociais relacionados à doença sob tratamento cirúrgico pode aumentar o risco de empobrecimento nacional à medida que aumenta o custo do tratamento. A Sociedade Brasileira de Cirurgia de Cabeça e Pescoço forneceu algumas recomendações e novas sugestões foram feitas para tratar com segurança essas condições cirúrgicas de alto risco potencial. Conclusão: As cirurgias para bócio e condições benignas da tireoide podem ser feitas durante a pandemia de Covid-19, se forem seguidos rigorosos protocolos de segurança para o paciente e equipe médica, o que reduz o impacto negativo na economia e na saúde do paciente.

Abstract Objective: Goiters and benign nodules detected in the thyroid are growing lesions and the COVID-19 pandemic have negatively impacted on their surgical treatment. The appropriate selection of patients to treatment will improve the overall health status. This article review will focus on the impact of the COVID-19 pandemic on treatment of benign conditions of the thyroid gland and their implications. Methods: This review pointed out the status of the health system in developing country and the problems to treat benign surgical diseases of thyroid. Aspects of epidemiology, incidence, clinical presentation and surgical treatment of goiters, economic and health status impact were cited. Results: All surgical treatment of goiter and other benign conditions were postponed, forced to redirect, and reschedule all benign surgeries, situation aggravated by poor public management and closure of hospital beds. These conditions have caused deterioration in patients’ physical (decompensated thyroid disease) and mental health status, increasing work disabilities and burdening society by increasing the social and health cost. The overall situation could be catastrophic in emergent countries where this increased disease-related social expenditure on surgical treatment may increase the risk of national impoverishment as increase the treatment cost. Brazilian Society Head and Neck Surgery related some recommendations and new suggestions were made to safely treat these high potential hazard surgical conditions. Conclusions: Surgeries for goiter and benign thyroid conditions can be performed during the COVID-19 pandemic, following strict safety protocols for the patient and the medical team, reducing the negative economic and on patient health impact.

https://doi.org/10.1016/j.bjorl.2021.08.008

Migración del Somatotipo en Jugadores de Fútbol Profesional en las Últimas Décadas
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Moya-Amaya, Heliodoro

; Molina-López, Antonio

; Berral-Aguilar, Antonio Jesús

; Rojano-Ortega, Daniel

; Berral-de-la-Rosa, Francisco José

International Journal of Morphology

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2022, Volume 40 N. 2 Pages 327 - 333

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: The aim of this study was to analyze the morphological configuration of soccer players of an Italian first division team and to compare it with research published in recent decades. A total of 23 players were evaluated at mid-season, using the anthropometric field method and the values were processed with the KINBIA® software. It was established that the somatotype of the sample is ecto-mesomorphic (1,52 - 4,7 - 2,63) and no significant differences were found between playing positions. A graphical representation of the somatotypes by playing position and somatotype migration from soccer researches of the last decades was made. It is concluded that the current elite soccer player has reduced the endomorphic component and there are non-significant differences in somatotype according to the playing position. The territory of influence of these athletes in the somatochart has been evolving over the last two decades, shifting from balanced mesomorphy to ecto-mesomorphy.

RESUMEN: El objetivo de este estudio fue analizar la configuración morfológica de los jugadores de fútbol de un equipo de la primera división italiana y compararlo con las investigaciones publicadas en las últimas décadas. Un total de 23 jugadores fueron evaluados a mitad de temporada, mediante el método de campo antropométrico y tratados los valores con el software KINBIA®. Se estableció que el somatotipo de la muestra es ecto-mesomorfo (1,52 - 4,7 - 2,63) y no se hallaron diferencias significativas entre las posiciones de juego. Se realizó una representación gráfica de los somatotipos por posición de juego y la migración del somatotipo de las investigaciones de fútbol de las últimas décadas. Se concluye que el futbolista de élite actual ha reducido más el componente endomórfico y que, en el mismo equipo, existen diferencias no significativas en el somatotipo según la posición de juego que desempeñen. El territorio de influencia de estos deportistas en la somatocarta ha ido evolucionando en las dos últimas décadas desplazándose desde la mesomorfia balanceada hacia la ecto-mesomorfia.

Cambios en la Composición Corporal y Ángulo de Fase Durante la Pretemporada en Jugadores de Fútbol Profesional
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Molina-López, Antonio

; Moya-Amaya, Heliodoro

; Estevan-Navarro, Pedro

; Berral-Aguilar, Antonio Jesús

; Rojano-Ortega, Daniel

; Berral-de-la-Rosa, Francisco José

International Journal of Morphology

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2022, Volume 40 N. 2 Pages 348 - 354

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: The analysis and control of body composition is essential in soccer due to its implication in performance. The aim of this study was to identify, in professional soccer players, the phase angle (PhA) of the lower limbs with possible patterns of improvement of the lean component measured by DEXA. At the same time, the evolution of hydric parameters of the players, subjected to intense training and nutritional control of their diet and supplementation, was studied by means of BIA. Eighteen players (26.28 ± 5.1 years; 85.09 ± 9.16 kg; 185.5 ± 4.32 cm) from an Italian first division football team were evaluated. The study was conducted for four weeks, between 11th July (pre- test) and 11th August of 2021 (post-test). The intervention was carried out entirely in pre-season, with confinement in isolation or total bubble mode for prevention of COVID-19 infection, where a high percentage of the player's life was monitored, including factors such as diet, training and rest. Supplementation was based on antioxidants, multivitamins, minerals and polyunsaturated fatty acids and two powdered products (one based on creatine, glutamine and leucine, and the other one, on essential amino acids). The players showed an improvement in PhA and in the lean component in the lower limbs, with a moderate correlation (r = 0.6). With regard to intracellular and extracellular water, it should be noted that, despite the high intensity of exercise during four weeks, these have remained constant without significant variations during the study period, indicating that there has not been a process of dehydration of the player.

RESUMEN: El análisis y el control de la composición corporal son claves en el fútbol por su implicación en el rendimiento. El objetivo de este estudio fue identificar, en jugadores de futbol profesional, el ángulo de fase (PhA) de miembros inferiores con los posibles patrones de mejora del componente magro en los mismos medido por DEXA. Al mismo tiempo, se estudió mediante BIA la evolución de parámetros hídricos de los jugadores, sometidos a un entrenamiento intenso y a un control nutricional de su alimentación y suplementación. Se evaluaron a 18 jugadores (26,28 ± 5,1 años; 85,09 ± 9,16 kg; 185,5 ± 4,32 cm) de un equipo de la primera división de fútbol italiana. Se llevó a cabo el estudio durante cuatro semanas, entre el 11 de julio (pre-test) y el 11 de agosto de 2021 (post-test). La intervención se llevó a cabo en su totalidad en pretemporada, con un confinamiento en modalidad de aislamiento o burbuja total por prevención al contagio del COVID-19, dónde se monitorizaba en un alto porcentaje la vida del jugador, incluyendo factores como la alimentación, el entrenamiento y el descanso. La suplementación estuvo basada en antioxidantes, multivitamínicos, minerales y ácidos grasos poliinsaturados y dos productos en polvo (uno a base de creatina, glutamina y leucina, y otro, a base de aminoácidos esenciales). Los jugadores presentaron una mejora del PhA y del componente magro en los miembros inferiores, con una moderada correlación (r = 0,6). Con respecto al agua intracelular y extracelular, señalar que, a pesar de la alta intensidad del ejercicio durante cuatro semanas, éstas se han mantenido constantes sin presentar variaciones significativas durante el periodo de estudio, lo que indica que no se ha producido un proceso de deshidratación del jugador.

Valoración de los factores de riesgo para la hipertensión arterial en adolescentes escolares
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Prieto-Peña, Ana Iris

; Molina-Estévez, Mirian Luisa

; Sánchez-Hernández, Daylis

; García-Prieto, Harold

Revista Médica Electrónica

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oct 2021, Volume 43 N. 5 Pages 1371 - 1382

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: essential arterial hypertension of the adult has its onset in childhood. Objective: to assess the influence of risk factors of essential arterial hypertension in adolescents of the Antonio Rodríguez Secundary School, in the municipality of Colón, province of Matanzas. Materials and methods: analytical study (prospective cohort observational) that constitutes a cut of the project "Prevention and control of hypertension in adolescents," of the Teaching Policlinic Dr. Carlos J. Finlay, in the period February to June 2016. Intentional non-probabilistic sampling, by criteria that included those 7th grade students who accepted, like their parents, to participate in the study. They were interviewed, measured, and had blood pressure measured. Sample: 160 teenagers. Variables: sex, body mass index, sedentarism, diabetes mellitus, smoking, alcohol intake, excessive salt intake, inadequate eating habits, low birth weight, maintained stress and family pathological history of hypertension. The SPSS 21 statistical package was used. Chi squared statistical test with µ = 0.05. Results: statistical significance was evidenced in innapropriate eating habits, family history of arterial hypertension, sedentarism and body mass index ≥ 25 in the onset of hypertension. 9 adolescents were identified without risk factors, all of them with normal arterial tension. 61,1 % showed three or more factors, including 100 % of the diagnosed hypertensives (5), and 17 prehypertensive ones (54,4 %). Conclusions: unhealthy ways and lifestyles and the presence of three or more risk factors were relevant in students high blood pressure.

RESUMEN Introducción: la hipertensión arterial esencial del adulto tiene sus inicios desde la niñez. Objetivo: valorar la influencia de factores de riesgo de hipertensión arterial esencial en adolescentes de la Escuela Secundaria Básica Antonio Rodríguez, del municipio Colón, provincia de Matanzas. Materiales y métodos: estudio analítico (observacional de cohorte prospectivo) que constituye un corte del proyecto “Prevención y control de la hipertensión arterial en adolescentes”, del Policlínico Docente Dr. Carlos J. Finlay, en el período de febrero a junio de 2016. Muestreo no probabilístico intencional, por criterios que incluyeron a aquellos estudiantes de 7mo grado que aceptaron, al igual que sus padres, la participación en el estudio. Se entrevistaron, mensuraron y se les midió la tensión arterial. Muestra: 160 adolescentes. Variables: sexo, índice de masa corporal, sedentarismo, diabetes mellitus, tabaquismo, ingestión de alcohol, ingestión excesiva de sal, hábitos alimentarios inadecuados, bajo peso al nacer, estrés mantenido y antecedentes patológicos familiares de hipertensión. Se utilizó el paquete estadístico SPSS 21. Test estadístico de Chi cuadrado con un µ = 0,05. Resultados: se evidenció significación estadística en los hábitos alimentarios no adecuados, antecedentes patológicos familiares de hipertensión arterial, sedentarismo e índice de masa corporal ≥ 25 en la aparición de hipertensión. Se identificaron 9 adolescentes sin factores de riesgo, todos con presión arterial normal. Con tres o más factores el 61,1 %, entre ellos el 100 % de los hipertensos diagnosticados (5) y 17 prehipertensos (54,4 %). Conclusiones: los modos y estilos de vida poco saludables y la presencia de tres o más factores de riesgo, fueron relevantes en los estudiantes con presión arterial elevada.

Clinical characteristics and outcomes among Brazilian patients with severe acute respiratory syndrome coronavirus 2 infection: an observational retrospective study
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Nascimento, Israel Júnior Borges do

; Pinto, Luiz Ricardo

; Fernandes, Valéria Alves

; Romero, Israel Molina

; Oliveira, João Antonio de Queiroz

; Marcolino, Milena Soriano

; Leite, Maria Fátima

Sao Paulo Medical Journal

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dec 2020, Volume 138 N. 6 Pages 490 - 497

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Since February 2020, data on the clinical features of patients infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their clinical evolution have been gathered and intensively discussed, especially in countries with dramatic dissemination of this disease. OBJECTIVE: To assess the clinical features of Brazilian patients with SARS-CoV-2 and analyze its local epidemiological features. DESIGN AND SETTING: Observational retrospective study conducted using data from an official electronic platform for recording confirmed SARS-CoV-2 cases. METHODS: We extracted data from patients based in the state of Pernambuco who were registered on the platform of the Center for Strategic Health Surveillance Information, between February 26 and May 25, 2020. Clinical signs/symptoms, case evolution over time, distribution of confirmed, recovered and fatal cases and relationship between age group and gender were assessed. RESULTS: We included 28,854 patients who were positive for SARS-CoV-2 (56.13% females), of median age 44.18 years. SARS-CoV-2 infection was most frequent among adults aged 30-39 years. Among cases that progressed to death, the most frequent age range was 70-79 years. Overall, the mortality rate in the cohort was 8.06%; recovery rate, 30.7%; and hospital admission rate (up to the end of follow-up), 17.3%. The average length of time between symptom onset and death was 10.3 days. The most commonly reported symptoms were coughing (42.39%), fever (38.03%) and dyspnea/respiratory distress with oxygen saturation < 95% (30.98%). CONCLUSION: Coughing, fever and dyspnea/respiratory distress with oxygen saturation < 95% were the commonest symptoms. The case-fatality rate was 8.06% and the hospitalization rate, 17.3%.

https://doi.org/10.1590/1516-3180.2020.00365.r1.08092020

Mental health, family roles and employment status inside and outside the household in Spain
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Torre, Jorge Arias-de la

; Molina, Antonio J.

; Fernández-Villa, Tania

; Artazcoz, Lucía

; Martín, Vicente

Gaceta Sanitaria

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jun 2019, Volume 33 N. 3 Pages 235 - 241

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Objective To document the prevalence of poor mental health by gender and social class, and to analyze if poor mental health is associated with the family roles or the employment status inside and outside the household. Method A cross-sectional study based on a representative sample of the Spanish population was carried out (n = 14,247). Mental health was evaluated using GHQ-12. Employment status, marital status, family roles (main breadwinner and the person who mainly carries out the household work) and educational level were considered as explanatory variables. Multiple logistic regression models stratified by gender and social class were fitted and adjusted odds ratios (aOR) were obtained. Results Gender and social class differences in the prevalence of poor mental health were observed. Unemployment was associated with higher prevalence. Among men the main breadwinner role was related to poor mental health mainly in those that belong to manual classes (aOR = 1.2). Among women, mainly among nonmanual classes, these problems were associated to marital status: widowed, separated or divorced (aOR = 1.9) and to dealing with the household work by themselves (aOR = 1.9). Conclusions In Spain, gender and social class differences in mental health still exist. In addition, family roles and working situation, both inside and outside the household, could constitute a source of inequalities in mental health.

RESUMEN Objetivo Conocer la prevalencia de mala salud mental por sexo y clase social, y analizar si la salud mental se relaciona con los roles familiares y la situación laboral fuera y dentro del hogar. Método Se realizó un diseño transversal basado en una muestra representativa de la población española (n = 14.247). La salud mental se evaluó mediante el GHQ-12. Se consideraron como variables explicativas la situación laboral, el estado civil, el rol familiar (sustentador principal y persona que realiza el trabajo doméstico) y el nivel de estudios. Se ajustaron modelos de regresión logística estratificados por sexo y se obtuvieron las odds ratio ajustadas (ORa). Resultados Se observaron diferencias en la prevalencia de mala salud mental por sexo y clase social. El desempleo se asoció con mayor prevalencia. En hombres pertenecientes a clases menos favorecidas, el rol de sustentador principal se relacionó con mala salud mental (Ora = 1,2) En mujeres que pertenecían a clases más favorecidas, el estado civil viuda, separada o divorciada (ORa = 1,9) y realizar el trabajo doméstico solas (ORa = 1,9) se relacionaron con mala salud mental. Conclusiones En España, en salud mental continúa habiendo diferencias de sexo y clase social. Además, el rol familiar y la situación laboral fuera y dentro del ámbito doméstico podrían constituir también una fuente de desigualdad en salud mental.

https://doi.org/10.1016/j.gaceta.2017.11.005 220 downloads

Mental health, family roles and employment status inside and outside the household in Spain
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Torre, Jorge Arias-de la

; Molina, Antonio J.

; Fernández-Villa, Tania

; Artazcoz, Lucía

; Martín, Vicente

Gaceta Sanitaria

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jun 2019, Volume 33 N. 3 Pages 235 - 241

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

https://doi.org/10.1016/j.gaceta.2017.11.005

Efecto de los antimaláricos sobre los diferentes dominios del índice de daño SLICC en pacientes de la cohorte GLADEL
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Pons-Estel, Guillermo J.

; Quintana, Rosana

; Wojdyla, Daniel

; Alarcón, Graciela S.

; Serrano, Rosa María

; Ugarte-Gil, Manuel

; Pimentel-Quiroz, Víctor

; Soriano, Enrique R.

; Catoggio, Luis J.

; Scolnik, Marina

; Sacnun, Mónica

; Saurit, Verónica

; Caeiro, Francisco

; Alvarellos, Alejandro

; Sarano, Judith

; García, Mercedes

; Onetti, Laura

; Drenkard, Cristina

; Berbotto, Guillermo

; Scherbarth, Hugo R.

; Sato, Emilia

; Bonfa, Eloisa

; Ferreira Borba, Eduardo

; Costallat, Lilian

; Xavier, Ricardo

; Tavares Brenol, Joao C.

; Da Silva, Nilzio A.

; Cavalcanti, Fernando

; Massardo, Loreto

; Jacobelli, Sergio

; Neira, Oscar

; Molina, José F

; Vásquez, Gloria

; Gómez-Puerta, José A.

; Alonso Gonzalez, Luis

; Iglesias Gamarra, Antonio

; Guibert-Toledano, Marlene

; Reyes, Gil A.

; Cardiel, Mario H.

; Pascual-Ramos, Virginia

; García de la Torre, Ignacio

; Barile, Leonor

; Silveira, Luis H.

; Amigo, Mary-Carmen

; Sauza del Pozo, María Josefina

; Acevedo-Vásquez, Eduardo M.

; Alfaro-Lozano, José

; Segami, María Inés

; Chacón-Díaz, Rosa

; Abadi, Isaac

; Esteva Spinetti, María H

; Pons-Estel, Bernardo A.

Revista argentina de reumatología

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sep 2018, Volume 29 N. 3 Pages 6 - 10

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objective: To assess the effects of antimalarials (AM) over the items of the SLICC Damage Index (SDI). Methods: Patients with recent (≤2 years) diagnosis of systemic lupus erythematosus (SLE) from the GLADEL cohort were studied. End-point: increase in items SDI since cohort entry. Independent variables (socio-demographic, clinical, laboratory and treatment) were included. The effect of AM as a time dependent variable on most frequent SDI items (adjusting for potential confounders) was examined with a multivariable Cox regression model. Results: Of the 1466 patients included in this analysis, 1049 (72%) received AM with a median exposure time of 30 months (Q1-Q3: 11-57). Damage occurred in 665 (45%) patients during a median follow-up time of 24 months (Q1-Q3: 8-55). There were 301 integument, 208 renal, 149 neuropsychiatric, 98 musculoskeletal, 88 cardiovascular and 230 others less frequently represented damages. After adjusting for potential confounders at any time during follow-up, a lower risk of renal damage (HR 0.652; 95% CI: 0.472-0.901) and borderline for neuropsychiatric damage (HR 0.701, 95% CI: 0.481-1.024) was found. Conclusion: In the GLADEL cohort, after adjustment for possible confounding factors, AM were independently associated with a reduced risk of renal damage accrual.

Objetivos: Estimar el efecto de los antimaláricos (AM) sobre los diferentes dominios del índice de daño SLICC (SDI). Métodos: Se estudiaron pacientes con diagnóstico clínico reciente (≤2 años) de lupus eritematoso sistémico (LES) de la cohorte GLADEL. Variable de estudio: aumento en los dominios del SDI desde el ingreso a la cohorte. Variables independientes: características sociodemográficas, clínicas, laboratorio y tratamientos. El efecto de los AM, como variable dependiente del tiempo, sobre los dominios más frecuentes del SDI (ajustado por factores de confusión) fue examinado con un modelo de regresión de Cox multivariado. Resultados: De 1466 pacientes estudiados, 1049 (72%) recibieron AM con un tiempo medio de exposición de 30 meses (Q1-Q3: 11-57) y 665 pacientes (45%) presentaron daño durante un seguimiento medio de 24 meses (Q1-Q3: 8-55); 301 eventos fueron cutáneos, 208 renales, 149 neuropsiquiátricos, 98 musculoesqueléticos, 88 cardiovasculares y 230 otros. Después de ajustar por factores de confusión, el uso de AM se asoció a un menor riesgo de daño renal (HR 0,652; IC 95%: 0,472-0,901) y en el límite de la significancia estadística (HR 0,701, IC 95%: 0,481-1,024) para el dominio neuropsiquiátrico. Conclusión: En GLADEL, el uso de AM se asoció independientemente a un menor riesgo de daño acumulado renal.

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Genetic diversity within wild species of Solanum
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Flores-Hernández, Luis Antonio

; Lobato-Ortiz, Ricardo

; Sangerman-Jarquín, Dora María

; García-Zavala, J. Jesús

; Molina-Galán, José D.

; Velasco-Alvarado, Mario de Jesús

; Marín-Montes, Iván Maryn

Revista Chapingo. Serie horticultura

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aug 2018, Volume 24 N. 2 Pages 85 - 96

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Cultivated tomato (Solanum lycopersicum L.) has undergone a reduction in its genetic base as a result of the processes of modern domestication and breeding, which has been extensively documented by molecular markers in different genotypes, both nationally and internationally. Faced with this situation, some plant breeders in Mexico have proposed making use of native Mexican germplasm, as well as of the genetic variation present in wild species related to the cultivated tomato. The aim of this study was to characterize agronomically, under greenhouse conditions, accessions of five wild relatives of the cultivated tomato for their incorporation into breeding programs of this vegetable. In addition, it is expected to reduce its vulnerability to climate change and adverse biotic and abiotic factors. The species described were Solanum pennellii L., Solanum pimpinellifollium L., Solanum peruvianum L., Solanum chilense R. and Solanum habrochaites S. The accessions were evaluated under greenhouse conditions under a completely randomized experimental design with four replications. Twelve traits of agronomic interest were evaluated to describe the variation between the accessions of each one of the evaluated species, which were studied by analysis of variance and comparison of means. The results showed high significance among the accessions of each one of the evaluated species for all the traits. The above shows that there is a high potential in each of the accessions of the species studied to exploit them genetically in the improvement of the cultivated tomato.

Resumen El jitomate (Solanum lycopersicum L.) ha sufrido reducción de su base genética durante los procesos de domesticación y mejoramiento genético moderno, lo que ha sido documentado ampliamente mediante marcadores moleculares en diferentes genotipos, tanto a nivel nacional como internacional. Ante esta situación, en México algunos fitomejoradores han planteado hacer uso de germoplasma nativo mexicano, así como de la variación genética presente en especies silvestres emparentadas con el jitomate cultivado. El objetivo del presente trabajo fue caracterizar agronómicamente, en condiciones de invernadero, accesiones de cinco parientes silvestres del jitomate para su incorporación en programas de mejoramiento genético de esta hortaliza. Además, con ello se espera reducir su vulnerabilidad frente al cambio climático y a factores bióticos y abióticos adversos. Las especies descritas fueron Solanum pennellii L., Solanum pimpinellifollium L., Solanum peruvianum L., Solanum chilense R. y Solanum habrochaites S. Las accesiones se evaluaron en condiciones de invernadero bajo un diseño experimental completamente al azar con cuatro repeticiones. Se evaluaron 12 variables de interés agronómico para describir la variación existente entre las accesiones de cada una de las especies evaluadas, las cuales se estudiaron mediante análisis de varianza y comparación de medias. Los resultados mostraron alta significancia entre las accesiones de cada una de las especies evaluadas para todas las variables. Lo anterior demuestra que existe un elevado potencial en cada una de las accesiones de las especies estudiadas para aprovecharlas genéticamente en el mejoramiento del jitomate cultivado.

https://doi.org/10.5154/r.rchsh.2017.08.030 978 downloads

10.

REFORMA UNIVERSITARIA: Manifiesto Liminar
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Barros, Enrique F.

; Valdés, Horacio

; Bordabehere, Ismael C.

; Sayago, Gurmensindo

; Castellanos, Alfredo

; Méndez, Luis M.

; Bazante, Jorge L.

; Garzón Maceda, Ceferino

; Molina, Julio

; Suárez Pinto, Carlos

; Biagosch, Emilio R.

; Nigro, Angel J.

; Saibene, Natalio J.

; Medina Allende, Antonio

; Garzón, Ernesto

Praxis educativa

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jan 2018, Volume 22 N. 1 Pages 95 - 98

Abstract: Es | Text: Es | PDF: Es

78 downloads

11.

Psychometric properties of the Spanish version of the 12-item Interpersonal Needs Questionnaire in fibromyalgia syndrome patients
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Ordoñez-Carrasco, Jorge L.

; Salgueiro, Monika

; Sayans-Jiménez, Pablo

; Blanc-Molina, Andrea

; García-Leiva, Juan Miguel

; Calandre, Elena P.

; Rojas, Antonio J.

Anales de Psicología

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2018, Volume 34 N. 2 Pages 273 - 281

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract According to the interpersonal theory of suicide, thwarted belongingness and perceived burdensomeness are key elements in the development of suicidal ideation. The Interpersonal Needs Questionnaire (INQ) was developed to assess the degree of frustration of these two interpersonal needs related to suicidal ideation. This study aims to analyze the psychometrics properties of a Spanish adaptation of INQ-12 in fibromyalgia patients. Exploratory factor analysis (n = 180) and confirmatory factor analysis (n = 179) were performed in two randomly selected sub-samples. The first analysis leads to the elimination of two items, whereas the second one confirmed the fit of the proposed two-factor structure. The reliability estimated using the Cronbach´s alpha coefficient and the Spearman-Brown coefficient was adequate. To obtain further validity evidence based on the relationship with other variables three variables were used. Moreover, a control group (n = 99) was used to contrast the means of INQ scores as evidence of validity based on differential scores. These findings support the usefulness of the Spanish version of the INQ-10 for assessing the degree of frustration of these interpersonal needs in patients with fibromyalgia.

Resumen Según la teoría interpersonal del suicidio, la pertenencia frustrada y la carga percibida son elementos clave en el desarrollo de la ideación suicida. El Cuestionario de necesidades interpersonales (INQ) fue diseñado para evaluar el grado de frustración de estas dos necesidades interpersonales relacionadas con la ideación suicida. El objetivo de este estudio fue analizar las propiedades psicométricas de una adaptación al español del INQ-12 en pacientes con fibromialgia. Un análisis factorial exploratorio (n = 180) y un análisis factorial confirmatorio (n = 179) fueron realizados en dos submuestras seleccionadas al azar. El primer análisis llevó a la eliminación de dos ítems, mientras que el segundo confirmó el ajuste de la estructura propuesta de dos factores. La fiabilidad estimada mediante el coeficiente alfa de Cronbach y el coeficiente Spearman-Brown fue adecuada. Para obtener evidencias de validez basadas en la relación con otros variables, se utilizaron tres variables relacionadas con el suicidio. Además, se utilizó un grupo control (n = 99) para contrastar los promedios de las puntuaciones INQ como evidencia de validez basada en puntajes diferenciales. Estos hallazgos respaldan la utilidad de la versión española del INQ-10 para evaluar el grado de frustración de estas necesidades interpersonales en pacientes con fibromialgia.

https://doi.org/10.6018/analesps.34.2.293101 584 downloads

12.

Declaración de Sant Joan d'Alacant en defensa del acceso abierto a las publicaciones científicas, del grupo de editores de revistas españolas sobre ciencias de la salud (GERECS)
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Sanz-Valero, Javier

; Melero Melero, Remedios

; Bojo Canales, Cristina

; Perdiguero Gil, Enrique

; Culebras Fernández, Jesús Manuel

; Wanden-Berghe, Carmina

; Ruiz López, Maria Dolores

; Amezcua Martínez, Manuel

; Alvarez-Dardet, Carlos

; Astrain Gallart, Mikel

; Vaquero Pérez, María del Mar

; López Montesinos, María José

; Sosa Henríquez, Manuel

; Pardal-Refoyo, José Luis

; Romero Medina, Agustín

; Primo Peña, Elena

; Hernández Merino, Ángel

; Torres Morera, Luis Miguel

; Bascones Martínez, Antonio

; Fernandez-Llimos, Fernando

; Rodríguez Portillo, Mariano

; Soldevilla Agreda, J. Javier

; Soriano del Castillo, José Miguel

; Ronda Pérez, Elena

; Rodríguez Álvaro, Martín

; Moreno Villares, Jose Manuel

; del Campo Balsa, Teresa

; Molina Olivas, Marta

; Almaraz Carretero, Julián

; Abadal, Ernest

; Crespo Montero, Rodolfo

; Dago Martínez, Ana

Cuadernos de Medicina Forense

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dec 2017, Volume 23 N. 3-4 Pages 112 - 114

Abstract: Es | Text: Es | PDF: Es

203 downloads

13.

Declaración de Sant Joan d'Alacant en defensa del Acceso Abierto a las publicaciones científicas, del grupo de editores de revistas españolas sobre ciencias de la salud (GERECS)
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Sanz-Valero, Javier

; Melero Melero, Remedios

; Bojo Canales, Cristina

; Perdiguero Gil, Enrique

; Culebras Fernández, Jesús Manuel

; Wanden-Berghe, Carmina

; Ruiz López, María Dolores

; Amezcua Martínez, Manuel

; Alvarez-Dardet, Carlos

; Astrain Gallart, Mikel

; Vaquero Pérez, María del Mar

; López Montesinos, María José

; Sosa Henríquez, Manuel

; Pardal-Refoyo, José Luis

; Romero Medina, Agustín

; Primo Peña, Elena

; Hernández Merino, Ángel

; Torres Morera, Luis Miguel

; Bascones Martínez, Antonio

; Fernández Llimos, Fernando

; Rodríguez Portillo, Mariano

; Soldevilla Agreda, J. Javier

; Soriano el Castillo, José Miguel

; Ronda Pérez, Elena

; Rodríguez Álvaro, Martín

; Moreno Villares, José Manuel

; del Campo Balsa, Teresa

; Molina Olivas, Marta

; Almaraz Carretero, Julián

; Abadal, Ernest

; Crespo Montero, Rodolfo

; Dago Martínez, Ana

Enfermería Nefrológica

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dec 2017, Volume 20 N. 4 Pages 291 - 293

Abstract: Es | Text: Es | PDF: Es

https://doi.org/10.4321/s2254-28842017000400002 162 downloads

14.

Efficacy of an internal teat seal associated with a dry cow intramammary antibiotic for prevention of intramammary infections in dairy cows during the dry and early lactation periods
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Molina, Lívio R.

; Costa, Hudson. N.

; Leão, Juliana M.

; Malacco, Victor M.R.

; Facury Filho, Elias J.

; Carvalho, Antônio U.

; Lage, Camila F.A.

Pesquisa Veterinária Brasileira

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may 2017, Volume 37 N. 5 Pages 465 - 470

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Objetivou-se avaliar o uso de um selante interno de tetos contendo subnitrato de bismuto (Teatseal®, Zoetis®, Florham Park, Nova Jersey, EUA) associado a um antibiótico de longa ação contendo cloxacilina (Orbenin® Extra dry cow, Zoetis®, Florham Park, Nova Jersey, EUA) em prevenir novas infecções durante o período seco e pós-parto imediato. Foram utilizadas 150 vacas Holandesas (produção média de 9,000 kg de leite por lactação), com os quatro quartos mamários funcionais e sem mastite clínica, que foram secas 60 dias antes da data prevista para o parto. O teto constituiu a unidade experimental. O grupo controle (C) foi representado por dois tetos diagonais-contralaterais (n=300), que receberam somente o antibiótico de vaca seca. Os outros dois tetos (n=300) constituíam o grupo tratado (T) e recebiam o antibiótico de vaca seca associado ao selante interno. Dados da variável contagem de células somáticas (CCS) passaram por transformação logarítmica na base 10 e foram submetidos ao teste de Duncan, aceitando-se nível de 5% de significância estatística. A ocorrência de infecções intramamárias (IIM), taxa de cronicidade e frequência de microrganismos isolados na secagem e imediatamente pós-parto nos tetos do grupo controle e tratados com selante interno foram avaliados utilizando o teste não paramétrico qui-quadrado, aceitando 10% de nível de significância. Houve redução na ocorrência de novas infecções no pós-parto imediato nos animais em que se utilizou o selante (C=19,6%, T=11,4%). No período pós-parto, foram isolados microrganismos Gram-negativo de 16 tetos no C e sete no T. A maior redução ocorreu para Escherichia coli, (8 versus 1) no grupo T. Não houve efeito da utilização do selante interno na frequência de isolamento de Streptococcus ambientais. O uso do selante reduziu a prevalência de mastite subclínica das vacas no pós-parto imediato (C=51% versus T=42%) e resultou em menor CCS no grupo tratado (T = 1.073 x 103) quando comparado com o grupo controle (C=1.793x103). O uso do selante interno combinado com antibiótico de vacas secas é eficaz na prevenção de infecções intramamárias no período seco e início de lactação e resulta na redução da CCS no período pós-parto imediato. O tratamento é eficaz na redução de infecção entre a secagem e o pós-parto imediato causada por patógenos maiores e menores. Entretanto, não tem efeito sobre infecções causadas por patógenos contagiosos.

ABSTRACT: The present study aimed to evaluate the use of an internal dry period teat seal containing bismuth subnitrate (Teatseal®, Zoetis®, Florham Park, Nova Jersey, USA) associated with a long-acting cloxacilin preparation (Orbenin® Extra dry cow, Zoetis®, Florham Park, Nova Jersey, USA), in preventing new infections during the dry-off and early postpartum period. A total of 150 Holstein cows (average production of 9,000 kg of milk per lactation), with four functional udder quarters without clinical mastitis was included in the study. All animals were dried-off 60 days before the expected calving date. Two teats positioned diagonal-contralaterally received only dry cow antibiotic, control group C (n=300) and the other two teats, treatment group T (n=300) received dry cow antibiotic and infusion with an internal teat seal. Data from SCC variable were transformed by log base-10 transformation. Duncan’s test was used accepting 5% as the level of statistical significance. The occurrence of intramammary infection (IMI) and chronicity rate, and frequency of microorganisms isolated at drying and immediately postpartum in teats of group C and group T were evaluated using a non-parametric Chi-square Test, accepting 10% as the statistical significance level. There was a decrease in the occurrence of new infections in the early postpartum in cows which the sealant was used (C=19.6%, T=11.4%). In the postpartum period, Gram-negative bacteria were isolated from 16 teats in C and seven in T. The greatest reduction was observed for Escherichia coli (8 vs 1) in group T. There was no effect using the internal sealant on the frequency of isolation of environmental Streptococus. The use of sealant reduced the prevalence of subclinical mastitis cows between drying-off and the early postpartum period (C=51% versus T=42%) and resulted in a lower somatic cell count (SCC) in the treatment group when compared with the control group (T=1,073x103, C=1,793x103). The use of the internal teat seal combined with dry cow antibiotic is effective in the prevention of IMI during the dry period and early lactation and results in the reduction of SCC in immediate postpartum period. The treatment is effective in reducing infection between dry-off and the immediate postpartum caused by major and minor pathogens. However, no effect on infections caused by contagious pathogens was observed.

https://doi.org/10.1590/s0100-736x2017000500007 1895 downloads

15.

Perfil mineral de vacas mestiças Girolanda no período de transição em sistema semi-intensivo em duas estações do ano
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Moreira, Tiago F.

; Zambrano, Jose U.

; Paula, Vitor M. de

; Casagrande, Fernando P.

; Facury Filho, Elias J.

; Molina, Lívio R.

; Leme, Fabíola O.P.

; Carvalho, Antônio U.

Pesquisa Veterinária Brasileira

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mar 2015, Volume 35 N. 3 Pages 249 - 257

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Neste estudo foi avaliado o perfil metabólico de vacas leiteiras no período de transição durante o verão e o inverno. Foram utilizados 31 animais pluríparos mestiços girolando em cada estação, totalizando 62 vacas. No verão permaneciam em pasto com suplementação de silagem de milho e concentrado. No inverno, a exigência nutricional era suprida apenas com silagem de milho e concentrado. Foram feitas um total de 11 coletas de sangue de cada animal segundo o seguinte protocolo: quatro coletas pré-parto espaçadas semanalmente, no dia do parto e com 2, 5, 10, 15, 21 e 30 dias pós-parto. Foram avaliadas as concentrações de cálcio, fósforo e magnésio. Todos os analitos variaram em função do estatus fisiológico. As concentrações médias de cálcio e magnésio foram maiores no verão do que no inverno. Em ambas as estações, as menores concentrações médias de cálcio ocorreram próximas ao parto, sendo que 75% dos animais no inverno e 35,48% dos animais no verão estavam hipocalcêmicos. Apenas no décimo dia as concentrações de cálcio voltaram aos níveis do pré-parto, demonstrando que esse tempo é necessário para a adaptação da nova condição de lactante. As concentrações de magnésio foram menores no pós-parto do que no pré-parto nas duas estações, demonstrando a necessidade desse mineral para a produção de leite. As concentrações médias de magnésio permaneceram sempre dentro dos valores de referência, porém 19% dos animais aos dois dias pós-parto no inverno e 7% dos animais aos 10 dias pós-parto no verão tinham concentrações inferiores a esses limites. As concentrações de fósforo sofreram grande variação ao longo do peri-parto, porém sempre em níveis elevados, sendo que 49,8% dos animais no inverno e 37,3% no verão tinham níveis de fósforo acima dos valores de referência

The metabolic profile of dairy cows in the transition period during summer and winter was evaluated. Were used 31 crossbred Holstein/Gir cows at each season, totaling 62 cows. During summer they remained in pasture with supplementation of corn silage and concentrate and in the winter, corn silage and concentrate was offered to furnish the nutritional requirements. A total of 11 blood samples from each animal were taken according to the following protocol: four collections weekly antepartum, at birth and at 2, 5, 10, 15, 21 and 30 days postpartum. Concentrations of calcium, phosphorus and magnesium were evaluated. All analytes varied according to the physiological status. The average concentrations of calcium and magnesium were higher in summer than in winter. In both seasons, the lowest mean calcium concentrations occurred near calving, and 75% of the animals in winter and 35.48% of the animals in the summer were hypocalcemic. Only on the tenth day postpartum, the calcium concentrations returned to levels of prepartum, demonstrating that this time is necessary for the adaptation of the new condition of lactating. Magnesium concentrations were lower postpartum than prepartum in both seasons, demonstrating the need for this mineral for the production of milk. The average concentrations of magnesium remained always within the reference values for the species, but 19% of the animals at two days postpartum in winter and 7% of the animals at 10 days postpartum in summer had concentrations below these limits. Phosphorus concentrations suffered large variation along the peri-partum, but always at high levels, with 49.8% of the animals in winter and 37.3% in summer had phosphorus levels above the reference range of the species.

https://doi.org/10.1590/S0100-736X2015000300007 2123 downloads

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