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au:Matos, Ana Raquel

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Participação pública em saúde e Covid-19 em Portugal
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Matos, Ana Raquel

; Craveiro, Isabel

Saúde em Debate

Journal Metrics
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nov 2022, Volume 46 N. spe4 Pages 107 - 119

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Nas últimas décadas, o tema da participação pública em processos de decisão tem estado presente nas agendas políticas, com mais ou menos centralidade, em vários contextos democráticos do mundo. No campo da saúde, a participação pública apresenta-se como estratégia política com potencialidades para garantir maior corresponsabilização entre os atores envolvidos e para incrementar a transparência dos serviços, sendo enfatizada como boa prática que deve ser implementada em prol da qualidade das decisões, mas também de decisões que sejam orientadas para os reais problemas das populações. A pandemia da Covid-19 trouxe pressões adicionais aos sistemas de saúde, constituindo-se como contexto propício à análise da participação cidadã nos processos de decisão que enquadram problemas de saúde na sua relação com a pandemia. Este ensaio apresenta uma análise exploratória sobre a evolução das práticas de participação cidadã nas políticas de saúde em Portugal, destacando alguns dos seus desafios atuais e futuros. Procura-se, assim, compreender como a pandemia teve ressonância na forma como a participação em saúde vinha decorrendo no País, aferindo se, em um período global de crise com características singulares, a pandemia, enquanto problema coletivo, distendeu ou contraiu essas práticas participativas.

ABSTRACT In the last decades, public participation in decision-making processes has been an ongoing theme, assuming more or less centrality, within the political agendas in several democratic contexts around the world. In the health domain, public participation has been considered a political strategy with the potential of ensuring greater co-responsibility among the actors involved, as well as to increase health services’ transparency, thus being emphasized as one of the best practices that should be implemented towards the quality of decisions, especially those oriented to the real health problems of the populations. The COVID-19 pandemic brought additional pressures to health systems, constituting itself as a conducive context to the analysis of citizen participation in health decision-making processes. This essay presents an exploratory analysis on the evolution of citizen participation practices in health policies in Portugal, highlighting some of its current and future challenges. The present analysis aims to understand how the pandemic resonated in the way in which participation in the health domain had been carried out in the country, assessing whether, in a singular global period of crisis, the pandemic as a collective problem expanded or contracted these participatory practices.

https://doi.org/10.1590/0103-11042022e408

[SciELO Preprints] - Public participation in health and Covid-19 in Portugal
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Matos, Ana Raquel Craveiro, Isabel

Journal Metrics
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Publication date: 2022-03-07

Abstract: En Pt

In the last decades, public participation in decision-making processes has been and ongoing theme, assuming more or less centrality, within the political agendas in several democratic contexts around the world. In the health domain, public participation has been considered a political strategy with the potential of ensuring greater co-responsibility among the actors involved, as well as to increase health services’ transparency. In this way, it has been emphasized as a best practice that should be implemented towards the quality of decisions, especially those oriented to the real health problems of the populations. The COVID-19 pandemic brought additional pressures to health systems, which constitutes itself as a conducive context to the analysis of citizen participation in health decision-making processes. This essay presents an exploratory analysis on the evolution of citizen’s participation practices in health policies in Portugal, highlighting some of its current and future challenges. The present analysis aims to understand how the pandemic had resonance in the way in which participation in the health domain had been carried out in the country, assessing whether, in a singular global period of crisis, the pandemic as a collective problem expanded or contracted these participatory practices.

Nas últimas décadas, o tema da participação pública em processos de decisão tem estado presente nas agendas políticas, com mais ou menos centralidade, em vários contextos democráticos do mundo. No campo da saúde, a participação pública apresenta-se como estratégia política com potencialidades para garantir maior corresponsabilização entre os atores envolvidos e para incrementar a transparência dos serviços, sendo enfatizada como boa prática que deve ser implementada em prol da qualidade das decisões, mas também de decisões que sejam orientadas para os reais problemas das populações.nbsp;A pandemia COVID-19 trouxe pressões adicionais aos sistemas de saúde, constituindo-se como contexto propício à análise da participação cidadã nos processos de decisão que enquadram problemas de saúde na sua relação com a pandemia. nbsp;Este ensaio apresentanbsp;uma análise exploratória sobre a evolução das práticas de participação cidadã nas políticas de saúde em Portugal, destacando alguns dos seus desafios atuais e futuros. Procura-se, assim,nbsp;compreender como a pandemia teve ressonância na forma como a participação em saúde vinha decorrendo no país, aferindo se, num período global de crise com características singulares, a pandemia enquanto problema coletivo distendeu ou contraiu estas práticas participativas.

https://doi.org/10.1590/SciELOPreprints.3735

Participação pública em saúde e Covid-19 em Portugal
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Matos, Ana Raquel

; Craveiro, Isabel

Saúde em Debate

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2022, Volume 46 N. spe4 Pages 107 - 119

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/0103-11042022e408

Association between calcium/magnesium ratio and insulin resistance in women with obesity and normal-weight women
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Clímaco-Cruz, Kyria Jayanne

; Oliveira, Ana Raquel Soares de

; Silva-Morais, Jennifer Beatriz

; Melo, Stéfany Rodrigues de Sousa

; Santos, Loanne Rocha dos

; Fontenelle, Larissa Cristina

; Freitas, Suelem Torres de

; Silva, Vladimir Costa

; Nery-Costa, Carlos Henrique

; Simeone-Henriques, Gilberto

; Matos Neto, Emídio Marques de

; Marreiro, Dilina do Nascimento

Revista chilena de nutrición

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oct 2021, Volume 48 N. 5 Pages 758 - 767

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT The aim of this study was to evaluate the association between the calcium/magnesium (Ca/Mg) ratio and insulin resistance in women with obesity and normal-weight women. This was a cross-sectional study with 128 women (62 women with obesity and 66 normal-weight women). We measured dietary minerals intake and analyzed magnesium and calcium biomarkers. Ca/Mg ratio in diet, plasma and urine were calculated. We have evaluated glycemic parameters. Women with obesity had low dietary magnesium, reduced plasma and erythrocyte magnesium concentrations, and elevated urinary magnesium excretion. Plasma calcium concentration was lower and urinary calcium excretion was higher in patients with obesity than in the normal-weight group. Dietary magnesium and calcium intake per kilogram of body weight per day was lower in obese women than in the control group. Ca/Mg ratio in plasma and urine were elevated in women with obesity. We found a significant correlation among magnesium biomarkers and calcium parameters. Ca/Mg ratio seems to be associated with insulin resistance in obese women.

RESUMEN El objetivo de este estudio fue evaluar la asociación entre la relación Ca/Mg y la resistencia a la insulina en mujeres con obesidad y en mujeres con peso normal. El diseño del estudio fue transversal y participaron 128 mujeres (62 mujeres con obesidad y 66 mujeres con peso normal). Se analizó la ingesta de minerales en la dieta y se realizaron análisis de biomarcadores de magnesio y calcio. Se calculó la relación Ca/Mg en dieta, plasma y orina y se evaluaron los parámetros glicémicos. Las mujeres con obesidad tenían niveles bajos de magnesio en la dieta, concentraciones reducidas de magnesio en plasma y eritrocitos, y excreción urinaria de magnesio elevada. La concentración plasmática de calcio fue menor en pacientes con obesidad, y la excreción urinaria de calcio fue mayor que en el grupo de mujeres con peso normal. La ingesta dietética de magnesio y calcio por kilogramo de peso corporal por día fue menor en las mujeres con obesidad, que en el grupo control. La relación Ca/Mg en plasma y orina estaba elevada en mujeres con obesidad. Se encontró una correlación significativa entre los biomarcadores de magnesio y los parámetros de calcio. La relación Ca / Mg parece estar asociada con la resistencia a la insulina en mujeres con obesidad.

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Ontologias do Antropoceno: Crise climática, respostas sociopolíticas e tecnologias emergentes
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Carvalho, António

; Ferreira, Vera

; Matos, Ana Raquel

Forum Sociológico

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jun 2021, N. 38 Pages 5 - 13

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O Antropoceno é uma época geológica proposta para ilustrar o impacto humano no sistema terrestre, exemplificado pelas alterações climáticas. Recorrendo a literatura no âmbito dos estudos de ciência e tecnologia, este artigo reflete sobre a heterogeneidade ontológica do Antropoceno, analisando como diferentes respostas sociais, políticas e tecnológicas são mobilizadas para fazer face aos desafios das alterações climáticas. O artigo analisa três estudos de caso que ilustram a heterogeneidade ontológica do Antropoceno : políticas europeias e nacionais em matéria de ação climática ; o movimento de transição, focado em ações à escala local para a descarbonização das sociedades ; a geoengenharia como tecnologia emergente de manipulação climática. Neste trabalho argumentamos que a diversidade de visões, práticas e intervenções associadas aos estudos de caso reforçam o carácter político e controverso do Antropoceno, colocando novos desafios às ciências sociais.

Abstract The Anthropocene is a proposed geological epoch to illustrate the human impact on Earth systems - exemplified by climate change. Supported by literature within science and technology studies, this article reflects on the ontological heterogeneity of the Anthropocene, analyzing how different social, political and technological proposals are mobilized to face the challenges of climate change. The article delves into three case studies that illustrate the ontological heterogeneity of the Anthropocene : European and national policies regarding climate change ; the Transition Movement, focused on local actions to foster low carbon transitions ; emerging technologies of climate manipulation - geoengineering. We argue that the diversity of visions, practices and interventions related to the case studies reinforce the political and controversial dimensions of the Anthropocene, posing new challenges for the social sciences.

https://doi.org/10.4000/sociologico.9693 62 downloads

Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
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Corrêa, Thiago Domingos

; Matos, Gustavo Faissol Janot de

; Bravim, Bruno de Arruda

; Cordioli, Ricardo Luiz

; Garrido, Alejandra del Pilar Gallardo

; Assuncao, Murillo Santucci Cesar de

; Barbas, Carmen Silvia Valente

; Timenetsky, Karina Tavares

; Rodrigues, Roseny dos Reis

; Guimarães, Hélio Penna

; Rabello Filho, Roberto

; Lomar, Frederico Polito

; Scarin, Farah Christina de La Cruz

; Batista, Carla Luciana

; Pereira, Adriano José

; Guerra, João Carlos de Campos

; Carneiro, Bárbara Vieira

; Nawa, Ricardo Kenji

; Brandão, Rodrigo Martins

; Pesaro, Antônio Eduardo Pereira

; Silva Júnior, Moacyr

; Carvalho, Fabricio Rodrigues Torres de

; Silva, Cilene Saghabi de Medeiros

; Almeida, Ana Claudia Ferraz de

; Franken, Marcelo

; Pesavento, Marcele Liliane

; Eid, Raquel Afonso Caserta

; Ferraz, Leonardo José Rolim

einstein (São Paulo)

Journal Metrics
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2020, Volume 18 elocation eAE5793

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Em dezembro de 2019, uma série de pacientes com pneumonia grave foi identificada em Wuhan, província de Hubei, na China. Esses pacientes evoluíram para síndrome respiratória aguda grave e síndrome do desconforto respiratório agudo. Posteriormente, a COVID-19 foi atribuída a um novo betacoronavírus, o coronavírus da síndrome respiratória aguda grave 2 (SARS-CoV-2). Cerca de 20% dos pacientes com diagnóstico de COVID-19 desenvolvem formas graves da doença, incluindo insuficiência respiratória aguda hipoxêmica, síndrome respiratória aguda grave, síndrome do desconforto respiratório agudo e insuficiência renal aguda e requerem admissão em unidade de terapia intensiva. Não há nenhum ensaio clínico randomizado controlado que avalie potenciais tratamentos para pacientes com infecção confirmada pela COVID-19 no momento da publicação destas recomendações de tratamento. Dessa forma, essas recomendações são baseadas predominantemente na opinião de especialistas (grau de recomendação de nível C).

ABSTRACT In December 2019, a series of patients with severe pneumonia were identified in Wuhan, Hubei province, China, who progressed to severe acute respiratory syndrome and acute respiratory distress syndrome. Subsequently, COVID-19 was attributed to a new betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Approximately 20% of patients diagnosed as COVID-19 develop severe forms of the disease, including acute hypoxemic respiratory failure, severe acute respiratory syndrome, acute respiratory distress syndrome and acute renal failure and require intensive care. There is no randomized controlled clinical trial addressing potential therapies for patients with confirmed COVID-19 infection at the time of publishing these treatment recommendations. Therefore, these recommendations are based predominantly on the opinion of experts (level C of recommendation).

https://doi.org/10.31744/einstein_journal/2020ae5793

Comment to: Intensive support recommendations for critically-ill patients with suspected or confirmed COVID-19 infection
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Corrêa, Thiago Domingos

; Matos, Gustavo Faissol Janot de

; Bravim, Bruno de Arruda

; Cordioli, Ricardo Luiz

; Garrido, Alejandra del Pilar Gallardo

; Assuncao, Murillo Santucci Cesar de

; Barbas, Carmen Silvia Valente

; Timenetsky, Karina Tavares

; Rodrigues, Roseny dos Reis

; Guimarães, Hélio Penna

; Rabello Filho, Roberto

; Lomar, Frederico Polito

; Scarin, Farah Christina de La Cruz

; Batista, Carla Luciana

; Pereira, Adriano José

; Guerra, João Carlos de Campos

; Carneiro, Bárbara Vieira

; Nawa, Ricardo Kenji

; Brandão, Rodrigo Martins

; Pesaro, Antônio Eduardo Pereira

; Silva Júnior, Moacyr

; Carvalho, Fabricio Rodrigues Torres de

; Silva, Cilene Saghabi de Medeiros

; Almeida, Ana Claudia Ferraz de

; Franken, Marcelo

; Pesavento, Marcele Liliane

; Eid, Raquel Afonso Caserta

; Ferraz, Leonardo José Rolim

einstein (São Paulo)

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2020, Volume 18 elocation eCE5931

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.31744/einstein_journal/2020ce5931

Quando nem a palavra é de prata, nem o silêncio é de ouro: Análise de conflitos sobre mineração em Portugal
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Matos, Ana Raquel

; Fernandes, Lúcia

Sociologia

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jun 2019, Volume 37 Pages 11 - 30

Este artículo analiza ocho casos de conflictos mineros en Portugal. El trabajo destaca las acciones de protesta desencadenadas y los impactos que éstas produjeron. Metodológicamente se privilegia el análisis documental. Los resultados revelan que la protesta colectiva es utilizada por las poblaciones afectadas para transmitir sus percepciones y argumentos sobre los problemas y hacer visibles las situaciones vividas. Las protestas realizadas confirieron mayor visibilidad a las particularidades de cada conflicto y produjeron cambios legislativos, aunque puntuales y específicos de ciertos casos.

Este artigo analisa oito casos de conflitos de mineração em Portugal, destacando as ações de protesto desencadeadas e os impactos que produziram. Metodologicamente privilegia a análise documental. Os resultados revelam a ação pelo protesto como recurso para as populações afetadas transmitirem as suas perceções e argumentos sobre os problemas enfrentados e tornarem visíveis as situações vividas. Os protestos realizados produziram alterações legislativas, embora pontuais e específicas de certos casos, e conferiram maior visibilidade às particularidades de cada caso.

Cet article analyse huit cas de conflits miniers au Portugal. Le travail met en évidence les actions de contestation déclenchées et les impacts qu'elles ont produits. La méthodologie d'analyse documentaire a été privilégiée. Les résultats révèlent que la mobilisation collective est un moyen pour les populations affectées de transmettre leurs perceptions et arguments et pour rendre visibles les situations vécues. Les manifestations ont conduit à des changements législatifs, bien que ponctuels et spécifiques à certains cas, et ont rendu visibles les particularités de chaque conflit.

This paper analyzes eight cases of mining conflicts in Portugal, focusing on the protest actions triggered, as well as the impacts they have produced. Methodologically, documentary analysis was undertaken. The results revealed collective action as the available resource for the affected populations to communicate their perceptions and arguments about the problems felt and to make their lived situations visible. Protest actions registered were able to produce legislative changes, even concerning specific situations, and gave visibility to the particularities of each case.

https://doi.org/10.21747/08723419/soc37a1 474 downloads

Antimicrobial Potential of Natural and Semi-Synthetic ent-Kaurane and ent-Pimarane Diterpenes against Clinically Isolated Gram-Positive Multidrug-Resistant Bacteria
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Soares, Ana Carolina F.

; Matos, Priscilla M.

; Silva, Karime F. da

; Martins, Carlos H. G.

; Veneziani, Rodrigo C. S.

; Ambrósio, Sérgio R.

; Dias, Herbert J.

; Santos, Raquel A. dos

; Heleno, Vladimir C. G.

Journal of the Brazilian Chemical Society

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feb 2019, Volume 30 N. 2 Pages 333 - 341

Abstract: En | Text: En | PDF: En

In this work, a search for antimicrobial agents against multi-drug resistant (MDR) bacteria was undertaken. It involved two natural diterpenes of different basic skeletons, named ent-kaurenoic acid and ent-pimaradienoic acid, that were used as precursors to access 28 semi-synthetic derivatives that were also submitted to biological assays. All 30 substances were assayed against a set of seven clinically isolated MDR bacteria, including three Staphylococcus aureus strains. Results classified both natural compounds as promising bactericidal antimicrobial agents against these MDR bacteria, especially for their performance in time-kill curve assay, improving on the positive control vancomycin. Moreover, di-hydro ent-pimaradienoic acid, obtained as one of the derivatives, also displayed promising minimum inhibitory concentration (MIC) values against the microorganism set, proving optimum activity against S. aureus strains. Thereby, this work also yielded a promising semi-synthetic bacteriostatic antimicrobial agent against MDR S. aureus. Furthermore, the study was carried out with 30 structures in order to verify the veracity and scope of Urzúa’s hypothesis about the structure-activity relationship between diterpenes and antimicrobial action. Our results are 93% in agreement with this hypothesis.

https://doi.org/10.21577/0103-5053.20180182

10.

Environmental effects and repeatability of the follicular diameter in mares
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Rua, Miguel Alejandro Silva

; Quirino, Celia Raquel

; Matos, Luis Fonseca

; Rodrigues, Ana Cláudia Cerqueira

; Bartholazzi Junior, Aylton

Revista Brasileira de Zootecnia

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2019, Volume 48 elocation e20190047

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate the effect of environment on follicular diameter and repeatability of the size of preovulatory follicles of mares. Temperature, rainfall, and photoperiod were measured, and their effects were evaluated on follicular dynamics. Data were studied by analysis of variance of follicular size and environment traits. During the five years, 7% double ovulations and 159 anovulatory follicles were recorded. Mean preovulatory follicle diameters of left and right ovaries were 39.3±3.8 and 39.2±3.5 mm respectively. There was no effect of evaluation year on follicular diameter. Reproduction season affected the right preovulatory follicle diameter. There was no effect of temperature and rainfall on follicular diameter. Repeatability values of the preovulatory follicular diameter were low. In the subtropical climate studied, temperature and rainfall caused no effect on follicular dynamics, and photoperiod had only a small effect on dominant preovulatory follicular diameter. Repeatability of follicular diameter was low, so this characteristic should be evaluated daily to predict ovulation and the optimal time to inseminate mares.

https://doi.org/10.1590/rbz4820190047

11.

A emergência do sujeito participativo: interseções entre ciência, política e ontologia
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Nunes, João Arriscado

; Costa, Daniel Neves da

; Carvalho, António

; Matos, Ana Raquel

Sociologias

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aug 2018, Volume 20 N. 48 Pages 162 - 187

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Nas últimas décadas, os dispositivos de participação pública têm registado um crescimento exponencial. Estes procedimentos podem assumir uma diversidade de configurações, gerando um número de questões teóricas e práticas. A partir da análise de dois estudos de caso - grupos de discussão sobre nanotecnologias em Coimbra, Portugal, e Conselhos de Saúde em Belo Horizonte, Brasil - este artigo oferece uma reflexão sobre as questões políticas e metodológicas relacionadas com a conceção e implementação de procedimentos participativos. A análise explora a emergência do cidadão participativo, associado a capacidades e formas de conhecimento que permitem a intervenção em espaços deliberativos. Argumenta-se que os dispositivos participativos e os processos de subjetivação estão interligados, dialogando-se com as reflexões de Foucault sobre subjetividade e com abordagens pós-humanistas no âmbito dos Estudos Sociais de Ciência e Tecnologia. Os dois estudos de caso ilustram como os procedimentos participativos geram novas capacidades epistémicas, retóricas e normativas associadas à habilitação e subjetivação dos participantes. Dessa forma, o artigo explora os aspetos políticos das práticas, metodologias e processos que suportam o envolvimento de cidadãos em ciência, tecnologia e saúde, contribuindo para a desnaturalização do sujeito participativo e para o reconhecimento da dimensão performativa das ciências sociais.

Abstract Over the last few decades, there has been a proliferation of devices of public participation. Those procedures can assume a wide range of configurations, generating a number of practical and theoretical issues. Drawing upon the analysis of two case studies - focus groups on nanotechnologies in Coimbra, Portugal, and Health Councils in Belo Horizonte, Brazil - this article reflects on political and methodological issues related to the conception and implementation of participatory devices. Our analysis explores the emergence of the participatory subject, intertwined with abilities and forms of knowledge that allow intervention in deliberative spaces. It is argued that participatory devices and subjectification processes are intertwined, following Foucault’s reflections on subjectivity and post-humanist approaches within Science and Technology Studies. The two case studies illustrate how participatory processes trigger new epistemic, rhetorical and normative capacities linked to the habilitation and subjectification of participants. In that sense, the article explores the political aspects of practices, methodologies and processes that support public engagement with science, technology and health, leading to the denaturalization of the participatory subject and to the recognition of the performative dimension of social sciences.

https://doi.org/10.1590/15174522-020004811

12.

Treatment of digital ulcers in systemic sclerosis: Case series study of thirteen patients and discussion on outcome
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Abuowda, Yahia

; Almeida, Raquel Sousa

; Oliveira, Ana Alves

; Pego, Petra

; Santos, Cristina

; Matos-Costa, João

Revista da Associação Médica Brasileira

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may 2017, Volume 63 N. 5 Pages 422 - 426

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: As úlceras digitais (UD) são complicações incapacitantes e recorrentes, associadas a menor qualidade de vida e maior mortalidade na esclerose sistêmica (ES). O tratamento baseia-se em antagonizar os mecanismos fisiopatológicos em causa. Objetivo: Descrever uma amostra de doentes com diagnóstico de ES e UD, o tratamento, as complicações e os resultados clínicos. Método: Série de 48 casos diagnosticados com ES, critérios de classificação ACR-EULAR 2013, seguidos entre 1999 e 2015, dos quais 13 apresentavam UD. O protocolo aplicado incluía ciclos de 21 dias de alprostadil podendo ser repetidos no caso de não existir cicatrização. Nos casos em que houve cicatrização foi iniciado bosentano. Resultados: No tratamento das UD, 12 doentes realizaram prostaciclina endovenosa, com necessidade de tratamentos repetidos em sete doentes. Doze doentes foram posteriormente tratados com bosentano, com recorrência de UD em três doentes, um deles com presença de anti-B2-GPI. Quatro doentes ficaram com cicatrizes e em três houve amputação digital, sendo casos de diagnóstico tardio. Conclusão: Os doentes mais jovens tiveram melhores resultados, possivelmente em razão de melhorias globais nos cuidados de saúde prestados e de referenciação precoce. A toxicidade dos antagonistas dos receptores da endotelina deve ser monitorizada, sobretudo em doentes com exposição prévia a drogas hepatotóxicas.

Summary Introduction: In systemic sclerosis (SSc), digital ulcers (DU) are debilitating and recurrent. They are markers of prognosis and are associated with disability and mortality. Treatment strategies have been developed to block the proposed mechanisms of this complication. Objective: Clinical description of a population of SSc patients with DU, treatment, complications and outcome. Method: Analysis of 48 SSc patients meeting 2013 ACR-EULAR criteria, followed between 1999-2015; 13 patients had DU. Treatment protocol applied included cycles of 21 days of alprostadil, which can be repeated in the absence of DU healing. After DU healing, bosentan was initiated. Results: DU healing was achieved with intravenous prostanoid in 12 patients; seven patients required repeated treatment for DU healing. Twelve patients were later treated with bosentan; three of them experienced recurrence of DU, while one was anti-B2-GPI positive. Four patients had soft tissue loss and three other suffered digital amputation, these being late diagnosis. Conclusion: Younger patients and early referrals had better outcomes. Endothelin receptor antagonist toxicity should be monitored, particularly in patients previously exposed to hepatotoxic drugs.

https://doi.org/10.1590/1806-9282.63.05.422

13.

Sensorineural hearing loss as the first manifestation of Sjögren's syndrome
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Almeida, Raquel Sousa

; Oliveira, Ana Alves

; Pego, Petra M.

; Abuowda, Yahia

; Gaspar, Iuri

; Costa, João Matos

Revista da Associação Médica Brasileira

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jan 2017, Volume 63 N. 1 Pages 7 - 9

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1806-9282.63.01.7

14.

O desafio da participação cidadã nos sistemas de saúde do Sul da Europa: uma revisão da literatura
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Matos, Ana Raquel

; Serapioni, Mauro

Cadernos de Saúde Pública

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2017, Volume 33 N. 1 elocation e00066716

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: O presente artigo versa sobre a análise de mecanismos de participação pública existentes nos sistemas de saúde dos países do Sul da Europa. Apresentam-se os resultados de uma revisão da literatura incidindo na questão da participação pública nos sistemas de saúde, realçando as potencialidades e os desafios que emergem das principais experiências nacionais identificadas, nos países considerados: Espanha, Grécia, Itália e Portugal. O artigo começa por caracterizar os sistemas de saúde, apresenta a metodologia utilizada e, posteriormente, os resultados da análise em cada país, com destaque para as diferentes formas de participação, institucionalizadas e não institucionalizadas. Como principal resultado da investigação, conclui-se que tem prevalecido um discurso legislativo que, na generalidade dos casos, não corresponde a práticas de participação efetivas, mas, por outro lado, têm emergido, com especial protagonismo na área da saúde, formas de participação não institucionalizada, nas quais se destacam ações de protesto, em grande parte, impulsionadas pela atual crise econômica.

Abstract: The current article analyzes existing mechanisms for public participation in health systems in the countries of Southern Europe. Results are presented from a literature review focusing on public participation in health systems, highlighting the potentialities and challenges emerging from the principal national experiences in the respective countries: Spain, Greece, Italy, and Portugal. The article begins by characterizing the health systems, then presents the methodology followed by the results of the analysis in each country, emphasizing the different forms of participation, both institutionalized and non-institutionalized. The study's principal conclusion is that a legislative discourse has prevailed, which in most cases has not materialized in actual participatory practices; meanwhile, non-institutionalized forms of participation have emerged with a special leading role in the health area, featuring protests, largely spurred by the current economic crisis.

Resumen: El presente artículo versa sobre el análisis de mecanismos de participación pública existentes en los sistemas de salud de países del sur de Europa. Se presentan los resultados de una revisión de la literatura, incidiendo en la cuestión de la participación pública en los sistemas de salud, realzando las potencialidades y los desafíos que emergen de las principales experiencias nacionales identificadas en los países considerados: España, Grecia, Italia y Portugal. El artículo comienza por caracterizar los sistemas de salud, presenta la metodología utilizada y, posteriormente, los resultados del análisis en cada país, resaltando las diferentes formas de participación, institucionalizadas y no institucionalizadas. Como principal resultado de la investigación, se concluye que ha prevalecido un discurso legislativo que, en la mayor parte de los casos, no corresponde a prácticas de participación efectivas, sin embargo, por otro lado, ha emergido, con especial protagonismo en el área de la salud, formas de participación no institucionalizada, en las que se destacan acciones de protesta, en gran parte, impulsadas por la actual crisis económica.

https://doi.org/10.1590/0102-311x00066716 618 downloads

15.

Viral hepatitis in female sex workers using the Respondent-Driven Sampling
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Matos, Marcos André de

; França, Divânia Dias da Silva

; Carneiro, Megmar Aparecida dos Santos

; Martins, Regina Maria Bringel

; Kerr, Lígia Regina Franco Sansigolo

; Caetano, Karlla Antonieta Amorim

; Pinheiro, Raquel Silva

; Araújo, Lyriane Apolinário de

; Mota, Rosa Maria Salani

; Matos, Marcia Alves Dias de

; Motta-Castro, Ana Rita Coimbra

; Teles, Sheila Araújo

Revista de Saúde Pública

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2017, Volume 51 elocation 65

Abstract: En | Text: En | PDF: En

ABSTRACT OBJECTIVE To estimate the prevalence of hepatitis B virus and C virus infections and their genotypes and analyze the risk factors for the markers of exposure to hepatitis B virus in female sex workers in a region of intense sex trade. METHODS This is a cross-sectional study performed with four hundred and two female sex workers in Goiânia, Brazil. Data have been collected using the Respondent-Driven Sampling. The women have been interviewed and tested for markers of hepatitis B and C viruses. Positive samples have been genotyped. The data have been analyzed using the Respondent-Driven Sampling Analysis Tool, version 5.3, and Stata 11.0. RESULTS The adjusted prevalence for hepatitis B virus and C virus were 17.1% (95%CI 11.6–23.4) and 0.7% (95%CI 0.1–1.5), respectively. Only 28% (95%CI 21.1–36.4) of the participants had serological evidence of vaccination against hepatitis B virus. Being older (> 40 years), being single, having a history of blood transfusion and use of cocaine, and ignoring the symptoms of sexually transmitted infections were associated with positivity for hepatitis B virus (p < 0.05). We have detected the subgenotype A1 of hepatitis B virus (n = 3) and the subtypes of hepatitis C virus 1a (n = 3) and 1b (n = 1). CONCLUSIONS We can observe a low prevalence of infection of hepatitis B and C viruses in the studied population. However, the findings of the analysis of the risk factors show the need for more investment in prevention programs for sexual and drug-related behavior, as well as more efforts to vaccinate this population against hepatitis B. The genotypes of the hepatitis B virus and C virus identified are consistent with those circulating in Brazil.

https://doi.org/10.1590/s1518-8787.2017051006540 273 downloads

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