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1.
Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management: Definition of Patient Blood Management hematology management
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Montano-Pedroso, Juan Carlos
; Macedo, Maria Cristina Martins de Almeida
; Biagini, Silvana
; Ribeiro, Glaciano
; Marques Junior, José Francisco Comenalli
; Rizzo, Silvia Renata Cornélio Parolin
; Rabello, Guilherme
; Langhi Junior, Dante Mario
.
Abstract Managing the patient's blood and hematopoietic system is like managing any of the other organs and organ systems during patient care. Specialists control the heart, kidneys, endocrine system, etc. and the patient's blood requires similar clinical treatment. The hematopoietic system and its circulatory products are fundamental for the healthy functioning of the human body. In simple terms, Patient Blood Management (PBM) is an organized, patient-centered approach in which the entire healthcare team coordinates efforts to improve outcomes by managing and preserving the patient's own blood. By reducing dependence on blood transfusions, PBM seeks to improve clinical outcomes, reduce the risks and costs associated with transfusions, and improve the safety and quality of patient care. Essentially, the concept of PBM is about the holistic management and preservation of the patient's own blood in the medical and surgical context. patients s care heart kidneys etc treatment body terms (PBM organized patientcentered centered transfusions Essentially context
2.
Absence of Leishmania spp. DNA in road-killed wild mammals in Southern Brazil spp roadkilled road killed
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Lignon, Julia Somavilla
; Pinto, Diego Moscarelli
; Teles, Mariana Accorsi
; Trindade, Maira Aparecida Christello
; Portela, Priscila Rockenbach
; Monteiro, Silvia Gonzalez
; Martins, Kauê Rodriguez
; Cunha, Rodrigo Casquero
; Pappen, Felipe Geraldo
; Bohm, Bianca Conrad
; Bruhn, Fábio Raphael Pascoti
.
Revista Brasileira de Parasitologia Veterinária
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Abstract Leishmaniasis are neglected diseases transmitted by vectors that affect domestic and wild animals, including humans. Due to its incidence and lethality, this zoonosis is a worrying public health problem, making it essential to identify all links in the transmission chain. Infection of wild mammals by Leishmania spp. remains poorly understood, especially in southern Brazil. Therefore, the objective was to research, using the PCR technique, the presence of Leishmania spp. DNA in road-killed wild mammals in Southern Brazil. Carcasses of 96 animals were collected from highways in the Pelotas microregion, Rio Grande do Sul, southern Brazil and subjected to necropsies. Tissue fragments (spleen, skin, liver, kidney, heart, lung, lymph nodes, bone marrow and blood) were collected and genomic DNA was extracted. PCR protocols targeting the ITS1, kDNA and 18S genes were tested. We found no evidence of Leishmania spp. circulation in the studied population. However, epidemiological studies like this one are of great relevance, as they allow monitoring of the occurrence of pathogens and help identify possible risk areas. As these animals act as epidemiological markers for the presence of the microorganism, studies must be carried out continuously to understand whether there are sources of infection in the region. humans lethality problem chain spp understood Therefore research technique roadkilled road killed 9 microregion Sul necropsies spleen, spleen (spleen skin liver kidney heart lung nodes blood extracted ITS1 ITS S tested population However relevance areas microorganism region
Resumo As leishmanioses são doenças negligenciadas, transmitidas por vetores que acometem animais domésticos e silvestres, incluindo os humanos. Devido a sua incidência e letalidade, essa zoonose consiste em um problema de saúde pública preocupante, sendo fundamental a identificação de todos os elos da cadeia de transmissão. A infecção de mamíferos silvestres por Leishmania spp. permanece pouco compreendida, especialmente no sul do Brasil. Portanto, objetivou-se pesquisar, por meio da técnica de PCR, a presença de DNA de Leishmania spp. em mamíferos silvestres atropelados no Sul do Brasil. Carcaças de 96 animais foram coletadas, em rodovias da microrregião de Pelotas, Rio Grande do Sul, sul do Brasil e submetidas a necropsias. Fragmentos de tecidos (baço, pele, fígado, rim, coração, pulmão, linfonodos, medula óssea e sangue) foram coletados e o DNA genômico foi extraído. Protocolos de PCR visando os genes ITS1, kDNA e 18S foram testados. Não foram encontradas evidências de circulação de Leishmania spp. na população estudada. Porém, estudos epidemiológicos como este são de grande relevância, pois permitem monitorar a ocorrência de patógenos e auxiliam na identificação de possíveis áreas de risco. Como esses animais atuam como marcadores epidemiológicos da presença do microrganismo, estudos devem ser realizados continuamente, para entender se existem fontes de infecção na região. negligenciadas humanos letalidade preocupante transmissão spp compreendida Portanto objetivouse objetivou pesquisar 9 coletadas Pelotas necropsias baço, baço (baço pele fígado rim coração pulmão linfonodos sangue extraído ITS1 ITS S testados estudada Porém relevância risco microrganismo continuamente região
3.
Processo de Doação de Órgãos Sólidos: Correlação entre Perfil, Aprendizagem e Indicação do Curso Sólidos Perfil
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Santos, Juliana Guareschi dos
; Calado, Dayana Aparecida Martins Correa
; Nascimento Neto, Jose Maria do
; Paglione, Heloisa Barboza
; Morgado, Silvia Regina
; Afonso Junior, Jose Eduardo
; Silva, Wander Plassa da
.
RESUMO Objetivos: Conhecer o perfil dos profissionais capacitados no processo de doação de órgãos sólidos, analisar o resultado de sua aprendizagem antes e após o curso, e correlacionar perfil e atuação do profissional com sua aprendizagem e indicação do curso. Métodos: Estudo retroprospectivo, quantitativo, analítico-descritivo com participantes do curso Processo de Doação de Órgãos Sólidos para Profissionais de Saúde. Utilizaram-se questionários online sobre perfil profissional, atuação na área de doação de órgãos, avaliação de conhecimento e indicação do curso. As análises e correlações foram verificadas com os testes de McNemar, postos de Spearman e ponto-bisserial. Resultados: Dos 130 profissionais, 62% eram enfermeiros, 38% médicos, 35% emergencistas, 26% intensivistas e 42% tinham mais de 10 anos de formação. Para o perfil de atuação na área de doação de órgãos, os profissionais relataram ter participado em até cinco casos em cada uma das seguintes etapas: 44% no protocolo de morte encefálica, 56% na entrevista familiar e 60% no processo de doação de órgãos. A taxa de retenção de conhecimento da turma foi de 26,7%, sendo a dos médicos 29,5% e a dos enfermeiros 24,8%. A indicação do curso foi avaliada seguindo o indicador Net Promoter Score (NPS), estando na zona de promotores. A correlação entre os grupos foi positiva e estatisticamente significante para os atuantes na emergência, com mais de 5 anos de formação e com mais de cinco casos relatados sobre as etapas questionadas na doação de órgãos. Não foi identificada correlação significativa dessas variáveis sobre a indicação do curso. Conclusão: O curso contribuiu para a aprendizagem dos profissionais com maior tempo de formação, maior experiência prévia nas etapas do processo de doação de órgãos e atuantes no setor de emergência. Objetivos sólidos Métodos retroprospectivo quantitativo analíticodescritivo analítico descritivo Saúde Utilizaramse Utilizaram se McNemar pontobisserial. pontobisserial ponto bisserial. bisserial ponto-bisserial Resultados 13 62 38 35 emergencistas 26 42 1 44 encefálica 56 60 267 7 26,7% 295 29 29,5 248 24 8 24,8% NPS, NPS , (NPS) promotores emergência Conclusão 6 3 2 4 26,7 29, 24,8 (NPS 26, 24,
ABSTRACT Objectives: To understand the profile of professionals trained in the solid organ donation process, to analyze the result of their learning before and after the course, and to correlate the profile and the performance of the professional with the learning and indication of the course. Methods: Retrospective, quantitative, analytical-descriptive study with participants of the course Processo de Doação de Órgãos Sólidos para Profissionais de Saúde. Online questionnaires were used on professional profile, performance in the area of organ donation, knowledge assessment, and course indication. The analyses and correlations were verified with the McNemar test, Spearman's rank, and the bisserial point. Results: Of the 130 professionals, 62% were nurses, 38% physicians, 35% emergency physicians, 26% intensivists, and 42% had more than 10 years of training. For the profile of work in the area of organ donation, the professionals report having participated in up to five cases in each of the following stages: 44% were involved in the brain death protocol, 56% in the family interview, and 60% in the organ donation process. The class knowledge retention rate was 26.7%, with 29.5% for physicians and 24.8% for nurses. The indication of the course was evaluated following the Net Promoter Score (NPS), being in the promoters zone. The correlation between the groups was positive and statistically significant for those working in the emergency room, with more than 5 years since graduation and with more than five cases reported on the questioned stages of organ donation. No significant correlation was identified between these variables and the indication of the course. Conclusion: The course contributed to the learning of professionals with more training time, greater previous experience in the stages of the organ donation process, and working in the emergency sector. Objectives process Methods Retrospective quantitative analyticaldescriptive analytical descriptive Saúde assessment test Spearmans Spearman s rank point Results 13 62 nurses 38 35 26 intensivists 42 1 44 protocol 56 interview 60 267 7 26.7% 295 29 29.5 248 24 8 24.8 NPS, NPS , (NPS) zone room Conclusion time sector 6 3 2 4 26.7 29. 24. (NPS 26.
4.
DNA rare copy number alterations in Reinke’s Edema Reinkes Reinke s
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Móz, Luis Eduardo Silva
; Martins, Regina Helena Garcia
; Lapa, Rainer Marco Lopez
; Villacis, Rolando André Rios
; Reis, Patricia Pintor dos
; Rogatto, Silvia Regina
.
Abstract Introduction: Reinke’s Edema (RE) is a laryngeal lesion related to excessive tobacco smoking, voice overuse, and laryngopharyngeal reflux. Although the risk of malignancy has been considered low in literature, RE is classified among precancerous lesions. Objectives: We investigated DNA Copy Number Alterations (CNAs) in specimens of RE and its potential association with malignant progression. Methods: We used array-based comparative genomic hybridization (aCGH, Agilent 4 × 180 K platform) to study eight RE cases. All patients were heavy tobacco users for at least 30 years, and none of them progressed to cancer in the follow-up (>8 years). Two RE presented mild dysplasia, one moderate dysplasia, and no histological alterations were found in the remaining five cases. CNAs were compared with the Database of Genomic Variants (DGV) and genes mapped on altered regions had their functions annotated. Results: Six of eight patients showed different rare copy number alterations on chromosomes 2q37.3, 4q13.1, 4q13.3, 7q11.22, 10p14, and 13q34. A gain of the whole chromosome 8 were detected in one case. Of interest, four of eight RE cases showed copy number imbalances involving genes previously described in several tumor types (RASA3, COL6A3, LINC00707, LINP1, SMR3A, and SMR3B). Conclusion: The genomic imbalances herein found in RE have the potential to contribute to the phenotype but with limited or no risk of cancer. A long-term follow-up in a large series of patients could clarify the mechanisms involved in the malignant progression of RE. Level of evidence: 4. Introduction Reinkes Reinke s (RE smoking overuse reflux literature lesions Objectives (CNAs Methods arraybased array based aCGH, aCGH (aCGH 18 platform 3 years followup follow up >8 (> years. . years) dysplasia DGV (DGV annotated Results 2q373 q 2q37 2q37.3 4q131 4q13 1 4q13.1 4q133 4q13.3 7q1122 7q11 22 7q11.22 10p14 p 13q34 case interest RASA3, RASA3 RASA (RASA3 COL6A3 COLA COL LINC00707 LINC LINP1 LINP SMR3A SMRA SMR SMR3B. SMR3B SMRB B SMR3B) Conclusion longterm long term evidence > ( 2q3 2q37. 4q1 4q13. 7q112 7q1 2 7q11.2 10p1 13q3 (RASA COL6A LINC0070 2q 4q 7q 7q11. 10p 13q LINC007 LINC00 LINC0
5.
L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor Lglutamine L glutamine Walker256 Walker 256 Walker-25 Walker25 25 Walker-2 Walker2 2 Walker-
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Lima, Kaio Ramon de Aguiar
; Lopes, Maria Luiza Diniz de Sousa
; Souza, Sara Raquel Garcia de
; Fracaro, Luciane
; Purificação, Natan Reyges Castro da
; Lima, Marília Fabiana de Oliveira
; Lins, Lucas Alexandre Araújo
; Lacchini, Silvia
; Araújo, Aurigena Antunes de
; Araújo Júnior, Raimundo Fernandes de
; Perles, Juliana Vanessa Colombo Martins
; Zanoni, Jacqueline Nelisis
; Clebis, Naianne Kelly
.
ABSTRACT Purpose: To evaluate the effects of the experimental subcutaneous Walker-256 tumor and L-glutamine supplementation, an antioxidant, on the glomerular morphology of rats. Methods: Twenty Wistar rats were distributed into four groups (n = 5): control (C); control treated with 2% L-glutamine (CG); rats with Walker-256 tumor (WT); and rats with Walker-256 tumor treated with 2% L-glutamine (WTG). Renal histological samples were submitted to periodic acid-Schiff and Masson’s Trichrome staining to analyze glomerular density, morphometry of glomerular components and glomerulosclerosis; and to immunohistochemistry for fibroblast growth factor-2 (FGF-2). Results: WT showed 50% reduction in body mass gain and cachexia index > 10%, while WTG demonstrated reduction in cachexia (p < 0.05). WT revealed reduction of glomerular density, increase in the glomerular tuft area, mesangial area, matrix in the glomerular tuft, decrease in the urinary space and synechia, and consequently higher glomerulosclerosis (p < 0.05). L-glutamine supplementation in the WTG improved glomerular density, and reduced glomerular tuft area, urinary space, mesangial area, and glomerulosclerosis compared to WT(p < 0.05). WT showed higher collagen area and FGF-2 expression compared to C (p < 0.05). WTG presented lower collagen fibers and FGF-2 expression compared to WT (p < 0.05). Conclusions: L-glutamine supplementation reduced cachexia and was beneficial for glomerular morphology of the rats, as well as it reduced kidney damage and improved the remaining glomeruli morphology. Purpose Walker256 Walker 256 Walker-25 Lglutamine L glutamine antioxidant Methods n 5 5) (C) 2 CG (CG) (WT) WTG. . (WTG) acidSchiff acid Schiff Massons Masson s density factor2 factor factor- FGF2. FGF2 FGF (FGF-2) Results 50 10 10% p 0.05. 005 0.05 0 05 0.05) synechia WTp FGF- Conclusions Walker25 25 Walker-2 (C (CG (WT (WTG (FGF-2 1 00 0.0 Walker2 Walker- (FGF- 0. (FGF
6.
Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues
; CURADO, Maria Paula
; PENAFORT, Paulo Victor Mendes
; DE ARRUDA, José Alcides Almeida
; ABREU, Lucas Guimarães
; MESQUITA, Ricardo Alves
; PINTO-JÚNIOR, Décio dos Santos
; ABRAHÃO, Aline Corrêa
; ANDRADE, Bruno Augusto Benevenuto de
; AGOSTINI, Michelle
; MORAES, Renata Mendonça
; ANBINDER, Ana Lia
; DOURADO, Pedro Henrique Silva
; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos
; PIRES, Fábio Ramoa
; BORDIGNON, Natalia Cristina Trentin
; GONDAK, Rogério Oliveira
; DE OLIVEIRA, Marcia Gaiger
; CARRARD, Vinicius Coelho
; MARTINS, Manoela Domingues
; SOUSA-NETO, Sebastião Silvério
; ARANTES, Diego Antônio Costa
; MENDONÇA, Elismauro Francisco
; CIESLAK-SANCHES, Silvia Roberta
; ANTUNES, Daniella Moraes
; AMARAL-SILVA, Gleyson Kleber do
; MANIERI, Patricia Rubia
; RAMALHO, Luciana Maria Pedreira
; DOS SANTOS, Jean Nunes
; LEONEL, Augusto César Leal da Silva
; PEREZ, Danyel Elias da Cruz
; VERHEUL, Hannah Carmem Carlos Ribeiro Silva
; BARROSO, Keila Martha Amorim
; RODRIGUES, Flávia Luiza Santos
; GONZAGA, Amanda Katarinny Goes
; FERNANDES, Romana Renery
; DE SOUZA, Lélia Batista
; SOUZA, Lucas Lacerda de
; PONTES, Flávia Sirotheau Corrêa
; PONTES, Hélder Antônio Rebelo
; SILVA, Caroline Alfaia
; CÂMARA, Jeconias
; LIBÓRIO-KIMURA, Tatiana Nayara
; SANTOS-SILVA, Alan Roger
; LOPES, Márcio Ajudarte
; ALMEIDA, Oslei Paes de
; ROMAÑACH, Mário José
; VARGAS, Pablo Agustin
.
Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System. (OMPLs SCC. . (SCC) crosssectional cross sectional North, North (North Northeast CentralWest, CentralWest Central West, West Central-West South. South South) 201 120010 120 010 120,01 20102019, 20102019 , (2010-2019) 69 6 9 6.9 8,321 8321 8 321 (8,32 0.8%, 08 0 (0.8% 95 cases, 4.9%, 49 4 (4.9% 5971 5 971 5,97 1.2%, 12 1 2 (1.2% 1399 399 1,39 Brazils s 64.5%, 645 64.5% 64 (64.5%) located men years level consumption group nonCaucasian non formercurrent former users Institute 99 9.9 Therefore System (SCC 20 12001 01 120,0 2010201 (2010-2019 6. 8,32 832 32 (8,3 0.8% (0.8 4.9% (4.9 597 97 5,9 1.2% (1.2 139 39 1,3 64.5 (64.5% 9. 1200 120, 201020 (2010-201 8,3 83 3 (8, 0.8 (0. 4.9 (4. 59 5, 1.2 (1. 13 1, 64. (64.5 20102 (2010-20 8, (8 0. (0 4. (4 1. (1 (64. (2010-2 ( (64 (2010- (6 (2010 (201 (20 (2
7.
Lesão Miocárdica e Prognóstico em Pacientes Hospitalizados com COVID-19 no Brasil: Resultados do Registro Nacional de COVID-19 COVID19 COVID 19 COVID-1 Brasil COVID1 1 COVID-
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Barbosa, Hannah Cardoso
; Martins, Maria Auxiliadora Parreiras
; Jesus, Jordana Cristina de
; Meira, Karina Cardoso
; Passaglia, Luiz Guilherme
; Sacioto, Manuela Furtado
; Bezerra, Adriana Falangola Benjamin
; Schwarzbold, Alexandre Vargas
; Maurílio, Amanda de Oliveira
; Farace, Barbara Lopes
; Silva, Carla Thais Cândida Alves da
; Cimini, Christiane Corrêa Rodrigues
; Silveira, Daniel Vitorio
; Carazai, Daniela do Reis
; Ponce, Daniela
; Costa, Emanuel Victor Alves
; Manenti, Euler Roberto Fernandes
; Cenci, Evelin Paola de Almeida
; Bartolazzi, Frederico
; Madeira, Glícia Cristina de Castro
; Nascimento, Guilherme Fagundes
; Velloso, Isabela Vasconcellos Pires
; Batista, Joanna d’Arc Lyra
; Morais, Júlia Drumond Parreiras de
; Carvalho, Juliana da Silva Nogueira
; Ruschel, Karen Brasil
; Martins, Karina Paula Medeiros Prado
; Zandoná, Liege Barella
; Menezes, Luanna Silva Monteiro
; Kopittke, Luciane
; Castro, Luís César de
; Nasi, Luiz Antônio
; Floriani, Maiara Anschau
; Souza, Maíra Dias
; Carneiro, Marcelo
; Bicalho, Maria Aparecida Camargos
; Lima, Maria Clara Pontello Barbosa
; Godoy, Mariana Frizzo de
; Guimarães-Júnior, Milton Henriques
; Mendes, Paulo Mascarenhas
; Delfino-Pereira, Polianna
; Ribeiro, Raquel Jaqueline Eder
; Finger, Renan Goulart
; Menezes, Rochele Mosmann
; Francisco, Saionara Cristina
; Araújo, Silvia Ferreira
; Oliveira, Talita Fischer
; Oliveira, Thainara Conceição de
; Polanczyk, Carisi Anne
; Marcolino, Milena Soriano
.
Abstract Background Cardiovascular complications of COVID-19 are important aspects of the disease’s pathogenesis and prognosis. Evidence on the prognostic role of troponin and myocardial injury in Latin American hospitalized COVID-19 patients is still scarce. Objectives To evaluate myocardial injury as independent predictor of in-hospital mortality and invasive mechanical ventilation support in hospitalized patients, from the Brazilian COVID-19 Registry. Methods This cohort study is a substudy of the Brazilian COVID-19 Registry, conducted in 31 Brazilian hospitals of 17 cities, March-September 2020. Primary outcomes included in-hospital mortality and invasive mechanical ventilation support. Models for the primary outcomes were estimated by Poisson regression with robust variance, with statistical significance of p<0.05. Results Of 2,925 patients (median age of 60 years [48-71], 57.1% men), 27.3% presented myocardial injury. The proportion of patients with comorbidities was higher among patients with cardiac injury (median 2 [1-2] vs. 1 [0-2]). Patients with myocardial injury had higher median levels of brain natriuretic peptide, lactate dehydrogenase, creatine phosphokinase, N-terminal pro-brain natriuretic peptide, and C-reactive protein than patients without myocardial injury. As independent predictors, C-reactive protein and platelet counts were related to the risk of death, and neutrophils and platelet counts were related to the risk of invasive mechanical ventilation support. Patients with high troponin levels presented a higher risk of death (RR 2.03, 95% CI 1.60-2.58) and invasive mechanical ventilation support (RR 1.87, 95% CI 1.57-2.23), when compared to those with normal troponin levels. Conclusion Cardiac injury was an independent predictor of in-hospital mortality and the need for invasive mechanical ventilation support in hospitalized COVID-19 patients. COVID19 COVID 19 COVID-1 diseases disease s prognosis scarce inhospital hospital Registry 3 cities MarchSeptember March September 2020 variance p005 p 0 05 p<0.05 2925 925 2,92 6 4871, 4871 48 71 , [48-71] 571 57 57.1 men, men men) 273 27 27.3 12 [1-2 vs 02. 02 . [0-2]) peptide dehydrogenase phosphokinase Nterminal N terminal probrain pro Creactive C reactive predictors RR 203 03 2.03 95 1.602.58 160258 1.60 2.58 58 1.60-2.58 187 87 1.87 1.572.23, 157223 1.57 2.23 23 1.57-2.23) COVID1 COVID- 202 p00 p<0.0 292 92 2,9 487 4 7 [48-71 5 57. 27. [1- [0-2] 20 2.0 9 602 1.602.5 16025 160 1.6 258 2.5 1.60-2.5 18 8 1.8 572 1.572.23 15722 157 1.5 223 2.2 1.57-2.23 p0 p<0. 29 2, [48-7 [1 [0-2 2. 1.602. 1602 16 1. 25 1.60-2. 1.572.2 1572 15 22 1.57-2.2 p<0 [48- [ [0- 1.602 1.60-2 1.572. 1.57-2. p< [48 [0 1.60- 1.572 1.57-2 [4 1.57-
Resumo Fundamento As complicações cardiovasculares da COVID-19 são aspectos importantes da patogênese e do prognóstico da doença. Evidências do papel prognóstico da troponina e da lesão miocárdica em pacientes hospitalizados com COVID-19 na América Latina são ainda escassos. Objetivos Avaliar a lesão miocárdica como preditor independente de mortalidade hospitalar e suporte ventilatório mecânico em pacientes hospitalizados, do registro brasileiro de COVID-19. Métodos Este estudo coorte é um subestudo do registro brasileiro de COVID-19, conduzido em 31 hospitais brasileiros de 17 cidades, de março a setembro de 2020. Os desfechos primários incluíram mortalidade hospitalar e suporte ventilatório mecânico invasivo. Os modelos para os desfechos primários foram estimados por regressão de Poisson com variância robusta, com significância estatística de p<0,05. Resultados Dos 2925 pacientes [idade mediana de 60 anos (48-71), 57,1%], 27,3% apresentaram lesão miocárdica. A proporção de pacientes com comorbidades foi maior nos pacientes com lesão miocárdica [mediana 2 (1-2) vs. 1 (0-20)]. Os pacientes com lesão miocárdica apresentaram maiores valores medianos de peptídeo natriurético cerebral, lactato desidrogenase, creatina fosfoquinase, N-terminal do pró-peptídeo natriurético tipo B e proteína C reativa em comparação a pacientes sem lesão miocárdica. Como fatores independentes, proteína C reativa e contagem de plaquetas foram relacionados com o risco de morte, e neutrófilos e contagem de plaquetas foram relacionados ao risco de suporte ventilatório mecânico invasivo. Os pacientes com níveis elevados de troponina apresentaram um maior risco de morte (RR 2,03, IC95% 1,60-2,58) e suporte ventilatório mecânico (RR 1,87;IC95% 1,57-2,23), em comparação àqueles com níveis de troponina normais. Conclusão Lesão cardíaca foi um preditor independente de mortalidade hospitalar e necessidade de suporte ventilatório mecânico em pacientes hospitalizados com COVID-19. COVID19 COVID 19 COVID-1 doença escassos COVID19. 19. COVID19, 19, 3 cidades 2020 invasivo robusta p005 p 0 05 p<0,05 292 idade 6 4871, 4871 48 71 , (48-71) 57,1%, 571 57,1% 57 57,1%] 273 27 27,3 12 (1-2 vs 020. 020 20 . (0-20)] cerebral desidrogenase fosfoquinase Nterminal N terminal própeptídeo pró independentes RR 203 03 2,03 IC95 IC 1,602,58 160258 1,60 2,58 58 1,60-2,58 1,87IC95% 187IC95 1,87 87 1,87;IC95 1,572,23, 157223 1,57 2,23 23 1,57-2,23) normais COVID1 COVID- 202 p00 p<0,0 29 487 4 7 (48-71 57,1 5 27, (1- 02 (0-20) 2,0 IC9 602 1,602,5 16025 160 1,6 258 2,5 1,60-2,5 87IC95 1,87IC95 187IC9 187 1,8 8 1,87;IC9 572 1,572,23 15722 157 1,5 223 2,2 1,57-2,23 p0 p<0, (48-7 57, (1 (0-20 2, 1,602, 1602 16 1, 25 1,60-2, 87IC9 1,87IC9 187IC 18 1,87;IC 1,572,2 1572 15 22 1,57-2,2 p<0 (48- ( (0-2 1,602 1,60-2 87IC 1,87IC 1,572, 1,57-2, p< (48 (0- 1,60- 1,572 1,57-2 (4 (0 1,57-
8.
Intrafamilial and extrafamilial sexual assault and its association with alcohol consumption
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Valle, Rubén
; Bernabé-Ortiz, Antonio
; Gálvez-Buccollini, Juan Antonio
; Gutiérrez, César
; Martins, Silvia S
.
ABSTRACT OBJECTIVE Analyze the prevalence of intrafamilial and extrafamilial sexual assault in adolescents of Peru and its association with alcohol consumption. METHODS We used a two-step and stratified probabilistic sampling to select male and female students in secondary education from all over Peru. The study included data from 54,756 students with information on demographics, alcohol and drug use, and sexual assault. The statistical analysis considered the complex sampling and we conducted two independent analyses by type of sexual assault (intrafamilial and extrafamilial), stratified by the sex of the victim. RESULTS The prevalence of life of intrafamilial sexual assaults (5.4%, 95%CI 5.0–5.8) was similar to that of extrafamilial sexual assaults (6.1%, 95%CI 5.6–6.6). Alcohol consumption in the past year was associated with intrafamilial and extrafamilial sexual assaults that occurred in the same period after adjusting for confounders. Alcohol consumption in the past year was associated with non-physical and physical forms of intrafamilial and extrafamilial sexual assaults in the disaggregated analysis by type of assault. Alcohol consumption in the past year was associated with extrafamilial rape only among females (ORa = 2.8; 95%CI 1.3–5.9). CONCLUSIONS Sexual assault against adolescent males and females by family members is a frequent form of victimization that is associated with alcohol consumption in Peru. It is important to examine this form of victimization among adolescents, especially those who consume alcohol.
RESUMEN OBJETIVO Analizar la prevalencia de las agresiones sexuales intrafamiliares y extrafamiliares en adolescentes del Perú y su asociación con el consumo de alcohol. MÉTODOS Se utilizó un muestreo probabilístico bietápico y estratificado para seleccionar estudiantes varones y mujeres de educación secundaria de todo el Perú. Los datos de 54,756 estudiantes que incluían información demográfica, sobre consumo de alcohol y drogas, y agresión sexual fueron incluidos en el estudio. En el análisis estadístico se consideró el muestreo complejo y se condujeron dos análisis independientes por el tipo de agresión sexual (intrafamiliar y extrafamiliar), estratificado por el sexo de la víctima. RESULTADOS La prevalencia de vida de las agresiones sexuales intrafamiliares (5.4%, IC95% 5.0–5.8) fue similar al de las agresiones extrafamiliares (6.1%, IC95% 5.6–6.6). El consumo de alcohol en el último año se asoció con las agresiones sexuales intrafamiliares y extrafamiliares que ocurrieron en el mismo periodo después de ajustar por los factores de confusión. El consumo de alcohol en el último año se asoció a las formas no físicas y físicas de agresión sexuales intrafamiliares y extrafamiliares en el análisis desagregado por tipo de agresión. El consumo de alcohol en el último año se asoció con las violaciones sexuales extrafamiliares sólo entre las mujeres (ORa = 2.8; IC95% 1.3–5.9). CONCLUSIONES La agresión sexual de adolescentes mujeres y varones por miembros familiares es una forma frecuente de victimización que se asocia al consumo de alcohol en el Perú. Es importante indagar por esta forma de victimización en adolescentes, especialmente los que consumen alcohol.
https://doi.org/10.11606/s1518-8787.2018052000539
3681 downloads
9.
Intrafamilial and extrafamilial sexual assault and its association with alcohol consumption
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Valle, Rubén
; Bernabé-Ortiz, Antonio
; Gálvez-Buccollini, Juan Antonio
; Gutiérrez, César
; Martins, Silvia S
.
ABSTRACT OBJECTIVE Analyze the prevalence of intrafamilial and extrafamilial sexual assault in adolescents of Peru and its association with alcohol consumption. METHODS We used a two-step and stratified probabilistic sampling to select male and female students in secondary education from all over Peru. The study included data from 54,756 students with information on demographics, alcohol and drug use, and sexual assault. The statistical analysis considered the complex sampling and we conducted two independent analyses by type of sexual assault (intrafamilial and extrafamilial), stratified by the sex of the victim. RESULTS The prevalence of life of intrafamilial sexual assaults (5.4%, 95%CI 5.0–5.8) was similar to that of extrafamilial sexual assaults (6.1%, 95%CI 5.6–6.6). Alcohol consumption in the past year was associated with intrafamilial and extrafamilial sexual assaults that occurred in the same period after adjusting for confounders. Alcohol consumption in the past year was associated with non-physical and physical forms of intrafamilial and extrafamilial sexual assaults in the disaggregated analysis by type of assault. Alcohol consumption in the past year was associated with extrafamilial rape only among females (ORa = 2.8; 95%CI 1.3–5.9). CONCLUSIONS Sexual assault against adolescent males and females by family members is a frequent form of victimization that is associated with alcohol consumption in Peru. It is important to examine this form of victimization among adolescents, especially those who consume alcohol.
RESUMEN OBJETIVO Analizar la prevalencia de las agresiones sexuales intrafamiliares y extrafamiliares en adolescentes del Perú y su asociación con el consumo de alcohol. MÉTODOS Se utilizó un muestreo probabilístico bietápico y estratificado para seleccionar estudiantes varones y mujeres de educación secundaria de todo el Perú. Los datos de 54,756 estudiantes que incluían información demográfica, sobre consumo de alcohol y drogas, y agresión sexual fueron incluidos en el estudio. En el análisis estadístico se consideró el muestreo complejo y se condujeron dos análisis independientes por el tipo de agresión sexual (intrafamiliar y extrafamiliar), estratificado por el sexo de la víctima. RESULTADOS La prevalencia de vida de las agresiones sexuales intrafamiliares (5.4%, IC95% 5.0–5.8) fue similar al de las agresiones extrafamiliares (6.1%, IC95% 5.6–6.6). El consumo de alcohol en el último año se asoció con las agresiones sexuales intrafamiliares y extrafamiliares que ocurrieron en el mismo periodo después de ajustar por los factores de confusión. El consumo de alcohol en el último año se asoció a las formas no físicas y físicas de agresión sexuales intrafamiliares y extrafamiliares en el análisis desagregado por tipo de agresión. El consumo de alcohol en el último año se asoció con las violaciones sexuales extrafamiliares sólo entre las mujeres (ORa = 2.8; IC95% 1.3–5.9). CONCLUSIONES La agresión sexual de adolescentes mujeres y varones por miembros familiares es una forma frecuente de victimización que se asocia al consumo de alcohol en el Perú. Es importante indagar por esta forma de victimización en adolescentes, especialmente los que consumen alcohol.
https://doi.org/10.11606/s1518-8787.2018052000539
16 downloads
10.
Trends in alcohol and tobacco use among Brazilian students: 1989 to 2010
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Sanchez, Zila M
; Prado, Mariangela Cainelli Oliveira
; Sanudo, Adriana
; Carlini, Elisaldo A
; Nappo, Solange A
; Martins, Silvia S
.
OBJETIVO Analisar a tendência temporal da prevalência de uso de álcool e tabaco por estudantes brasileiros. MÉTODOS Foram analisados, entre 1989 e 2010, dados de cinco inquéritos epidemiológicos com estudantes do sexto ano do ensino fundamental ao terceiro do ensino médio, matriculados em escolas públicas nas 10 maiores capitais do Brasil. A amostra foi de 104.104 estudantes e os dados foram coletados em sala de aula. O instrumento de coleta – questionário de autopreenchimento da Organização Mundial da Saúde – e os procedimentos de amostragem e ponderação foram os mesmos nos cinco inquéritos. Teste de Qui-quadrado de tendências foi utilizado para comparar as prevalências entre os anos. RESULTADOS A prevalência de uso de álcool e tabaco variou nos anos e entre as capitais estudadas. O uso de álcool diminuiu em todas as 10 capitais (p < 0,001), em 21 anos. Houve também diminuição significativa do uso de tabaco em oito capitais (p < 0,001). A maior prevalência de uso de álcool foi observada na região Sudeste, em 1993 (72,8% em Belo Horizonte), e a menor, em Belém (30,6%), em 2010. A maior prevalência de uso do tabaco no último ano foi na região Sul, em 1997 (28,0% em Curitiba) e a menor na região Sudeste, em 2010 (7,8% em São Paulo). CONCLUSÕES A tendência de queda na prevalência de tabagismo e uso de álcool entre estudantes, observada em todo o País, pode estar relacionada com políticas antitabaco e antiálcool bem-sucedidas e abrangentes. Apesar destes resultados, a prevalência de uso de álcool no último ano continuou elevada em todas as regiões brasileiras.
OBJECTIVE To analyze temporal trends of the prevalence of alcohol and tobacco use among Brazilian students. METHODS We analyzed data published between 1989 and 2010 from five epidemiological surveys on students from the 6th to the 12th grade of public schools from the ten largest state capitals of Brazil. The total sample consisted of 104,104 students and data were collected in classrooms. The same collection tool – a World Health Organization self-reporting questionnaire – and sampling and weighting procedures were used in the five surveys. The Chi-square test for trend was used to compare the prevalence from different years. RESULTS The prevalence of alcohol and tobacco use varied among the years and cities studied. Alcohol consumption decreased in the 10 state capitals (p < 0.001) throughout 21 years. Tobacco use also decreased significantly in eight cities (p < 0.001). The highest prevalence of alcohol use was found in the Southeast region in 1993 (72.8%, in Belo Horizonte) and the lowest one in Belem (30.6%) in 2010. The highest past-year prevalence of tobacco use was found in the South region in 1997 (28.0%, in Curitiba) and the lowest one in the Southeast in 2010 (7.8%, in Sao Paulo). CONCLUSIONS The decreasing trend in the prevalence of tobacco and alcohol use among students detected all over the Country can be related to the successful and comprehensive Brazilian antitobacco and antialcohol policies. Despite these results, the past-year prevalence of alcohol consumption in the past year remained high in all Brazilian regions.
https://doi.org/10.1590/S0034-8910.2015049005860
4356 downloads
11.
Trends in alcohol and tobacco use among Brazilian students: 1989 to 2010
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Facebook Twitter
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- Metrics
Sanchez, Zila M
; Prado, Mariangela Cainelli Oliveira
; Sanudo, Adriana
; Carlini, Elisaldo A
; Nappo, Solange A
; Martins, Silvia S
.
OBJETIVO Analisar a tendência temporal da prevalência de uso de álcool e tabaco por estudantes brasileiros. MÉTODOS Foram analisados, entre 1989 e 2010, dados de cinco inquéritos epidemiológicos com estudantes do sexto ano do ensino fundamental ao terceiro do ensino médio, matriculados em escolas públicas nas 10 maiores capitais do Brasil. A amostra foi de 104.104 estudantes e os dados foram coletados em sala de aula. O instrumento de coleta – questionário de autopreenchimento da Organização Mundial da Saúde – e os procedimentos de amostragem e ponderação foram os mesmos nos cinco inquéritos. Teste de Qui-quadrado de tendências foi utilizado para comparar as prevalências entre os anos. RESULTADOS A prevalência de uso de álcool e tabaco variou nos anos e entre as capitais estudadas. O uso de álcool diminuiu em todas as 10 capitais (p < 0,001), em 21 anos. Houve também diminuição significativa do uso de tabaco em oito capitais (p < 0,001). A maior prevalência de uso de álcool foi observada na região Sudeste, em 1993 (72,8% em Belo Horizonte), e a menor, em Belém (30,6%), em 2010. A maior prevalência de uso do tabaco no último ano foi na região Sul, em 1997 (28,0% em Curitiba) e a menor na região Sudeste, em 2010 (7,8% em São Paulo). CONCLUSÕES A tendência de queda na prevalência de tabagismo e uso de álcool entre estudantes, observada em todo o País, pode estar relacionada com políticas antitabaco e antiálcool bem-sucedidas e abrangentes. Apesar destes resultados, a prevalência de uso de álcool no último ano continuou elevada em todas as regiões brasileiras.
OBJECTIVE To analyze temporal trends of the prevalence of alcohol and tobacco use among Brazilian students. METHODS We analyzed data published between 1989 and 2010 from five epidemiological surveys on students from the 6th to the 12th grade of public schools from the ten largest state capitals of Brazil. The total sample consisted of 104,104 students and data were collected in classrooms. The same collection tool – a World Health Organization self-reporting questionnaire – and sampling and weighting procedures were used in the five surveys. The Chi-square test for trend was used to compare the prevalence from different years. RESULTS The prevalence of alcohol and tobacco use varied among the years and cities studied. Alcohol consumption decreased in the 10 state capitals (p < 0.001) throughout 21 years. Tobacco use also decreased significantly in eight cities (p < 0.001). The highest prevalence of alcohol use was found in the Southeast region in 1993 (72.8%, in Belo Horizonte) and the lowest one in Belem (30.6%) in 2010. The highest past-year prevalence of tobacco use was found in the South region in 1997 (28.0%, in Curitiba) and the lowest one in the Southeast in 2010 (7.8%, in Sao Paulo). CONCLUSIONS The decreasing trend in the prevalence of tobacco and alcohol use among students detected all over the Country can be related to the successful and comprehensive Brazilian antitobacco and antialcohol policies. Despite these results, the past-year prevalence of alcohol consumption in the past year remained high in all Brazilian regions.
https://doi.org/10.1590/S0034-8910.2015049005860
1683 downloads
12.
Growing knowledge: an overview of Seed Plant diversity in Brazil
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Zappi, Daniela C.
; Filardi, Fabiana L. Ranzato
; Leitman, Paula
; Souza, Vinícius C.
; Walter, Bruno M.T.
; Pirani, José R.
; Morim, Marli P.
; Queiroz, Luciano P.
; Cavalcanti, Taciana B.
; Mansano, Vidal F.
; Forzza, Rafaela C.
; Abreu, Maria C.
; Acevedo-Rodríguez, Pedro
; Agra, Maria F.
; Almeida Jr., Eduardo B.
; Almeida, Gracineide S.S.
; Almeida, Rafael F.
; Alves, Flávio M.
; Alves, Marccus
; Alves-Araujo, Anderson
; Amaral, Maria C.E.
; Amorim, André M.
; Amorim, Bruno
; Andrade, Ivanilza M.
; Andreata, Regina H.P.
; Andrino, Caroline O.
; Anunciação, Elisete A.
; Aona, Lidyanne Y.S.
; Aranguren, Yani
; Aranha Filho, João L.M.
; Araújo, Andrea O.
; Araújo, Ariclenes A.M.
; Araújo, Diogo
; Arbo, María M.
; Assis, Leandro
; Assis, Marta C.
; Assunção, Vivian A.
; Athiê-Souza, Sarah M.
; Azevedo, Cecilia O.
; Baitello, João B.
; Barberena, Felipe F.V.A.
; Barbosa, Maria R.V.
; Barros, Fábio
; Barros, Lucas A.V.
; Barros, Michel J.F.
; Baumgratz, José F.A.
; Bernacci, Luis C.
; Berry, Paul E.
; Bigio, Narcísio C.
; Biral, Leonardo
; Bittrich, Volker
; Borges, Rafael A.X.
; Bortoluzzi, Roseli L.C.
; Bove, Cláudia P.
; Bovini, Massimo G.
; Braga, João M.A.
; Braz, Denise M.
; Bringel Jr., João B.A.
; Bruniera, Carla P.
; Buturi, Camila V.
; Cabral, Elza
; Cabral, Fernanda N.
; Caddah, Mayara K.
; Caires, Claudenir S.
; Calazans, Luana S.B.
; Calió, Maria F.
; Camargo, Rodrigo A.
; Campbell, Lisa
; Canto-Dorow, Thais S.
; Carauta, Jorge P.P.
; Cardiel, José M.
; Cardoso, Domingos B.O.S.
; Cardoso, Leandro J.T.
; Carneiro, Camila R.
; Carneiro, Cláudia E.
; Carneiro-Torres, Daniela S.
; Carrijo, Tatiana T.
; Caruzo, Maria B.R.
; Carvalho, Maria L.S.
; Carvalho-Silva, Micheline
; Castello, Ana C.D.
; Cavalheiro, Larissa
; Cervi, Armando C.
; Chacon, Roberta G.
; Chautems, Alain
; Chiavegatto, Berenice
; Chukr, Nádia S.
; Coelho, Alexa A.O.P.
; Coelho, Marcus A.N.
; Coelho, Rubens L.G.
; Cordeiro, Inês
; Cordula, Elizabeth
; Cornejo, Xavier
; Côrtes, Ana L.A.
; Costa, Andrea F.
; Costa, Fabiane N.
; Costa, Jorge A.S.
; Costa, Leila C.
; Costa-e-Silva, Maria B.
; Costa-Lima, James L.
; Cota, Maria R.C.
; Couto, Ricardo S.
; Daly, Douglas C.
; De Stefano, Rodrigo D.
; De Toni, Karen
; Dematteis, Massimiliano
; Dettke, Greta A.
; Di Maio, Fernando R.
; Dórea, Marcos C.
; Duarte, Marília C.
; Dutilh, Julie H.A.
; Dutra, Valquíria F.
; Echternacht, Lívia
; Eggers, Lilian
; Esteves, Gerleni
; Ezcurra, Cecilia
; Falcão Junior, Marcus J.A.
; Feres, Fabíola
; Fernandes, José M.
; Ferreira, D.M.C.
; Ferreira, Fabrício M.
; Ferreira, Gabriel E.
; Ferreira, Priscila P.A.
; Ferreira, Silvana C.
; Ferrucci, Maria S.
; Fiaschi, Pedro
; Filgueiras, Tarciso S.
; Firens, Marcela
; Flores, Andreia S.
; Forero, Enrique
; Forster, Wellington
; Fortuna-Perez, Ana P.
; Fortunato, Reneé H.
; Fraga, Cléudio N.
; França, Flávio
; Francener, Augusto
; Freitas, Joelcio
; Freitas, Maria F.
; Fritsch, Peter W.
; Furtado, Samyra G.
; Gaglioti, André L.
; Garcia, Flávia C.P.
; Germano Filho, Pedro
; Giacomin, Leandro
; Gil, André S.B.
; Giulietti, Ana M.
; A.P.Godoy, Silvana
; Goldenberg, Renato
; Gomes da Costa, Géssica A.
; Gomes, Mário
; Gomes-Klein, Vera L.
; Gonçalves, Eduardo Gomes
; Graham, Shirley
; Groppo, Milton
; Guedes, Juliana S.
; Guimarães, Leonardo R.S.
; Guimarães, Paulo J.F.
; Guimarães, Elsie F.
; Gutierrez, Raul
; Harley, Raymond
; Hassemer, Gustavo
; Hattori, Eric K.O.
; Hefler, Sonia M.
; Heiden, Gustavo
; Henderson, Andrew
; Hensold, Nancy
; Hiepko, Paul
; Holanda, Ana S.S.
; Iganci, João R.V.
; Imig, Daniela C.
; Indriunas, Alexandre
; Jacques, Eliane L.
; Jardim, Jomar G.
; Kamer, Hiltje M.
; Kameyama, Cíntia
; Kinoshita, Luiza S.
; Kirizawa, Mizué
; Klitgaard, Bente B.
; Koch, Ingrid
; Koschnitzke, Cristiana
; Krauss, Nathália P.
; Kriebel, Ricardo
; Kuntz, Juliana
; Larocca, João
; Leal, Eduardo S.
; Lewis, Gwilym P.
; Lima, Carla T.
; Lima, Haroldo C.
; Lima, Itamar B.
; Lima, Laíce F.G.
; Lima, Laura C.P.
; Lima, Leticia R.
; Lima, Luís F.P.
; Lima, Rita B.
; Lírio, Elton J.
; Liro, Renata M.
; Lleras, Eduardo
; Lobão, Adriana
; Loeuille, Benoit
; Lohmann, Lúcia G.
; Loiola, Maria I.B.
; Lombardi, Julio A.
; Longhi-Wagner, Hilda M.
; Lopes, Rosana C.
; Lorencini, Tiago S.
; Louzada, Rafael B.
; Lovo, Juliana
; Lozano, Eduardo D.
; Lucas, Eve
; Ludtke, Raquel
; Luz, Christian L.
; Maas, Paul
; Machado, Anderson F.P.
; Macias, Leila
; Maciel, Jefferson R.
; Magenta, Mara A.G.
; Mamede, Maria C.H.
; Manoel, Evelin A.
; Marchioretto, Maria S.
; Marques, Juliana S.
; Marquete, Nilda
; Marquete, Ronaldo
; Martinelli, Gustavo
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Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.
Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.
https://doi.org/10.1590/2175-7860201566411
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