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Abstract Background: Patients using immunosuppressive drugs may have unfavorable results after infections. However, there is a lack of information regarding COVID 19 in these patients, especially in patients with rheumatoid arthritis (RA). Therefore, the aim of this study was to evaluate the risk factors associated with COVID 19 hospitalizations in patients with RA. Methods: This multicenter, prospective cohort study is within the ReumaCoV Brazil registry and included 489 patients with RA. In this context, 269 patients who tested positive for COVID 19 were compared to 220 patients who tested negative for COVID 19 (control group). All patient data were collected from the Research Electronic Data Capture database. Results: The participants were predominantly female (90.6%) with a mean age of 53 ±12 years. Of the patients with COVID 19, 54 (20.1%) required hospitalization. After multiple adjustments, the final regression model showed that heart disease (OR =4.61, 95% CI 1.06–20.02. P < 0.001) and current use of glucocorticoids (OR =20.66, 95% CI 3.09–138. P < 0.002) were the risk factors associated with hospitalization. In addition, anosmia was associated with a lower chance of hospitalization (OR =0.26; 95% CI 0.10–0.67, P < 0.005). Conclusion: Our results demonstrated that heart disease and the use of glucocorticoids were associated with a higher number of hospital admissions for COVID 19 in patients with RA. Trial registration: Brazilian Registry of Clinical Trials RBR 33YTQC.

https://doi.org/10.1186/s42358-022-00244-5

Outcome of SARS-CoV-2 and immune thrombocytopenia in a pediatric patient
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Soares, Ana Cláudia Carramaschi Villela

; Loggetto, Sandra Regina

; Manga, Fernanda Cristina Marinho

; Faustino, Laira Rita

; Braga, Josefina Aparecida Pellegrini

Hematology, Transfusion and Cell Therapy

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mar 2021, Volume 43 N. 1 Pages 101 - 103

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.htct.2020.09.145 181 downloads

Cigarro Eletrônico: Mocinho ou vilão?
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Lima Menezes, Iasmim

; Mendes Sales, Julianna

; Neves Azevedo, Joyce Karoline

; Canuto Figueirêdo Junior, Ernani

; Aparecida Marinho, Sandra

Revista Estomatológica Herediana

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jan 2021, Volume 31 N. 1 Pages 28 - 36

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

SUMMARY Objective: to discuss the health effects caused by the use of electronic cigarettes. Material and Methods : A search was performed in the PubMed/Medline database of complete articles published in the last 10 years. A total of 21 articles were used, according to the established inclusion criteria, with a higher prevalence of cross-sectional studies. Results: It was verified that electronic cigarettes may even help in the cessation of conventional smoking, however, their users are not exempt from suffering systemic health complications. They present toxic substances and should not be considered totally safe and harmless. Conclusions : Further studies are still needed to determine the implications of the use of this electronic device on the health of its users in the long term.

RESUMEN Objetivo: Discutir los efectos sobre la salud causados por el uso de cigarrillos electrónicos. Material y métodos: Para ello, se realizó una búsqueda en la base de datos PubMed/Medline de artículos completos publicados en los últimos 10 años. Se utilizaron un total de 21 artículos, según los criterios de inclusión establecidos, con mayor prevalencia de estudios transversales. Resultados: Se encontró que los cigarrillos electrónicos pueden incluso ayudar en el cese del tabaquismo convencional, sin embargo, sus usuarios no están exentos de sufrir complicaciones de salud sistémicas. Estos contienen sustancias tóxicas y no deben considerarse completamente seguros e inofensivos. Conclusiones: se necesitan más estudios para determinar las implicaciones para la salud a largo plazo del uso de este deben considerarse completamente seguros e inofensivos.

https://doi.org/10.20453/reh.v31i1.3923

Effects of clown activities on patients eligible for palliative care in primary health care
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Santos, Fernando Ribeiro dos

; Pinto, Sandra

; Pessalacia, Juliana Dias Reis

; Luchesi, Bruna Moretti

; Silva, Lucimeire Aparecida da

; Marinho, Maristela Rodrigues

Revista Brasileira de Enfermagem

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2021, Volume 74 N. 5 elocation e20200431

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Avaliar os efeitos de atividades clown na qualidade de vida, depressão, estresse, ansiedade, apoio e suporte social em pacientes elegíveis para cuidados paliativos (CP) atendidos na Atenção Primária à Saúde (APS). Método: Estudo quase-experimental, com avaliação pré-intervenção e pós-intervenção, realizado com 16 pacientes elegíveis para CP precoces na APS em um município do Centro-Oeste. Os pacientes receberam 24 visitas com atividades clown domiciliares. Resultados: As intervenções evidenciaram melhora da qualidade de vida e do suporte social, com resultados significativos para a dimensão Atividades sociais (p = 0,023). Também observou-se aumento de pontuação para Ansiedade (p = 0,007) e Depressão (p = 0,023). Conclusão: As atividades clown podem trazer resultados positivos para a qualidade de vida e suporte social de pacientes elegíveis para CP em domicílio. Devem ser incentivadas para interagir com o saber das famílias e potencializar o cuidado humanizado, integral e centrado das relações humanas na APS.

ABSTRACT Objective: Evaluate the effects of clown activities on quality of life, depression, stress, anxiety, aid, and social support in patients eligible for palliative care (PC) attended in Primary Health Care (PHC). Method: A quasi-experimental study, with pre-intervention and post-intervention evaluation, carried out with 16 patients eligible for early PC in PHC in a Midwestern city. Patients received 24 visits with home-based clown activities. Results: The interventions evidenced improved quality of life and social support, with significant results for the Social Activities dimension (p = 0.023). Increased scores for Anxiety (p = 0.007) and Depression (p = 0.023) were also observed. Conclusion: Clown activities can bring positive results for the quality of life and social support of patients eligible for PC at home. They should be encouraged to interact with family knowledge and enhance humanized care, integral and centered on human relationships in PHC.

RESUMEN Objetivo: Evaluar efectos de actividades clown en calidad de vida, depresión, estrés, ansiedad, apoyo y soporte social en pacientes elegibles para cuidados paliativos (CP) atendidos en Atención Primaria de Salud (APS). Método: Estudio cuasi-experimental, con evaluación preintervención y posintervención, realizado con 16 pacientes elegibles para CP precoces en la APS en municipio del medio oeste. Pacientes recibieron 24 visitas con actividades clown domiciliarias. Resultados: Intervenciones evidenciaron mejora de la calidad de vida y del suporte social, con resultados significativos para la dimensión Actividades Sociales (p = 0,023). También se observó aumento de puntuación para Ansiedad (p = 0,007) y Depresión (p = 0,023). Conclusión: Actividades clown pueden traer resultados positivos a la calidad de vida y suporte social de pacientes elegibles para CP en domicilio. Deben ser incentivadas para interaccionar con el saber familiar y potencializar el cuidado humanizado, integral y centrado de las relaciones humanas en la APS.

https://doi.org/10.1590/0034-7167-2020-0431 274 downloads

Dor, ansiedade e qualidade de vida relacionada à saúde bucal de pacientes atendidos no serviço de urgência odontológica
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Queiroz, Mariane Flauzino

; Verli, Flaviana Dornela

; Marinho, Sandra Aparecida

; Paiva, Paula Cristina Pelli

; Santos, Suelleng Maria Cunha

; Soares, Janir Alves

Ciência & Saúde Coletiva

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apr 2019, Volume 24 N. 4 Pages 1277 - 1286

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste estudo foi avaliar associação entre dor pré-operatória, ansiedade e impacto da condição bucal na qualidade de vida dos pacientes atendidos no serviço de Urgência Odontológica da Universidade Federal dos Vales do Jequitinhonha e Mucuri. Estudo transversal retrospectivo foi conduzido avaliando dados clínicos de 240 prontuários de pacientes com idades entre 18 e 65 anos. A dor foi mensurada pela Heft-Parker Visual Analogue Scale; ansiedade, pela Corah’s Detal Anxiety Scale e qualidade de vida, pelo Oral Health Impact Profile (OHIP-14). Associações foram analisadas pelo Teste qui-quadrado de Pearson (p < 0,05). Foi observada associação estatisticamente significante entre dor e pior qualidade de vida, com impacto nos domínios desconforto psicológico (p < 0,001), incapacidade física (p < 0,001), psicológica (p < 0,001) e social (p < 0,001). Ansiedade influenciou na pior qualidade de vida, com impacto nos domínios desconforto psicológico (p = 0,009), incapacidade fisica (p = 0,016), psicológica (p = 0,011) e desvantagem social (p = 0,028). Esse estudo é relevante para o planejamento de ações voltadas para a saúde bucal dos pacientes atendidos nos serviços de urgência odontológica, priorizando aqueles com maiores impactos psicossociais decorrentes dos problemas bucais.

Abstract The scope of this study was to assess the association between preoperative pain, anxiety and the impact of the oral condition on the quality of life of patients treated at the Dental Emergency Service at the Federal University of the Jequitinhonha and Mucuri Valleys. A retrospective cross-sectional study was conducted evaluating data from 240 patient charts aged from 18 to 65 years. Pain was measured by the Heft-Parker Visual Analog Scale; dental anxiety by Corah’s Dental Anxiety Scale; and oral health-related quality of life by the Oral Health Impact Profile (OHIP-14). Associations were analyzed using Pearson’s Chi-square test (p < 0.05). A statistically significant association was observed between pain and poorer quality of life, with impacts on psychological discomfort (p < 0.001), physical incapacity (p < 0.001) and the psychological (p < 0.001) and social (p < 0.001) domains. Anxiety influenced poorer quality of life, with impacts on the psychological discomfort (p = 0.009), physical disability (p = 0.016), psychological disability (p = 0.011) and social disadvantage (p = 0.028) domains. This study is relevant for the planning of programs and actions aimed at the oral health of patients treated in dental emergency services, prioritizing those with the greatest psychosocial impact arising from oral problems.

https://doi.org/10.1590/1413-81232018244.33802016 4149 downloads

Dor, ansiedade e qualidade de vida relacionada à saúde bucal de pacientes atendidos no serviço de urgência odontológica
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Queiroz, Mariane Flauzino

; Verli, Flaviana Dornela

; Marinho, Sandra Aparecida

; Paiva, Paula Cristina Pelli

; Santos, Suelleng Maria Cunha

; Soares, Janir Alves

Ciência & Saúde Coletiva

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apr 2019, Volume 24 N. 4 Pages 1277 - 1286

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232018244.33802016

Excisão de um fibroma de células gigantes com laser cirúrgico
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de Morais Neves, Lucas Emmanuell

; Gonçalves de Carvalho, Sérgio Henrique

; de Santana Sarmento, Dmitry José

; dos Santos Pereira, Joabe

; Gomes Agripino, Gustavo

; Aparecida Marinho, Sandra

Revista Cubana de Estomatología

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dec 2018, Volume 55 N. 4 Pages 1 - 10

Abstract: Pt | Text: Pt | PDF: Pt

Dental trauma clinically mimicking single central incisor syndrome
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Moreira, Rafaela Nogueira

; Verli, Flaviana Dornela

; Marinho, Sandra Aparecida

; Canuto, Conceição Eunice

; Costa, Altair Borges

; Marques, Leandro Silva

Revista Odonto Ciência

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2012, Volume 27 N. 1 Pages 78 - 81

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

OBJETIVO: Apresentar um caso clínico de ausência de um incisivo central perdido por traumatismo e encaminhado ao ortodontista com suspeita de apresentar síndrome do incisivo central único (SMMCI). DESCRIÇÃO DO CASO: Paciente gênero feminino, 12 anos com queixa da aparência de seus dentes. Ao exame intrabucal observou-se a presença de um incisivo central único localizado na linha média sem espaçamentos em relação aos incisivos laterais superiores. A paciente relatou dois episódios de avulsão dos dentes 11 e 21, cerca de quatro anos antes. No entanto, devido a sintomas de dor após reimplante, o dente 11 foi extraído. A radiografia panorâmica e análise cefalométrica revelou a presença de tratamento insatisfatório do canal radicular do dente 21, um perfil reto e padrão de equilíbrio facial. Extração do dente 21 foi realizada, com tração posterior dos dentes superiores na direção mesial, seguido pela transformação estética dos incisivos laterais em incisivos centrais e dos caninos em incisivos laterais. CONCLUSÃO: O traumatismo seguido de perda dentária pode mimetizar um quadro de síndrome do incisivo central único.

PURPOSE: This paper presents a clinical case in which a patient was missing a median central incisor due to trauma but was referred for orthodontic treatment because of suspicions of solitary median maxillary central incisor (SMMCI) syndrome. CASE DESCRIPTION: A 12-year-old female patient visited the clinic with concerns about the appearance of her teeth. An oral examination revealed the presence of a single central incisor that was located on the midline and was adjacent to the maxillary lateral incisors. The patient reported two episodes of dental avulsion (of teeth 11 and 21) that had occurred approximately four years earlier. Tooth 11 was replanted; however, it was subsequently extracted due to pain. A panoramic radiograph and cephalometric analysis revealed a history of unsuccessful root canal treatment on tooth 21, a straight profile and symmetrical facial features. Tooth 21 was extracted, followed by the traction of the maxillary teeth in the mesial direction and the esthetic transformation of the lateral incisors into central incisors and the canines into lateral incisors. CONCLUSION: Dental trauma followed by tooth loss may mimic solitary median maxillary central incisor syndrome.

4193 downloads

Identification of Candida spp. by phenotypic tests and PCR
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Marinho, Sandra Aparecida

; Teixeira, Alice Becker

; Santos, Otávio Silveira

; Cazanova, Ricardo Flores

; Ferreira, Carlos Alexandre Sanchez

; Cherubini, Karen

; Oliveira, Sílvia Dias de

Brazilian Journal of Microbiology

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jun 2010, Volume 41 N. 2 Pages 286 - 294

Abstract: En | Text: En | PDF: En

The correct identification of Candida species is of great importance, as it presents prognostic and therapeutical significance, allowing an early and appropriate antifungical therapy. The purpose of this study was to identify isolates of Candida spp. from oral mucosa of 38 patients with oral candidosis evaluated in 2004 by phenotypic methods and PCR, discriminating C. albicans from the other Candida species. The tests used for phenotypic analysis were germ-tube and chlamydoconidia production, culture in CHROMAgarTM Candida, carbohydrate assimilation test, growth at 45ºC and culture in Tween 80 agar. Genotypic confirmation was performed by PCR. Phenotypic tests showed that 63.2% strains formed germ-tubes, 73.7% produced chlamydoconidia, and 63.2% showed green colonies in chromogenic medium, presumptively indicating C. albicans or C. dubliniensis. The carbohydrate assimilation test confirmed these results. A total of 21% strains were identified as C. krusei and 13.2% were indicative of C. tropicalis. Of these later strains, three produced chlamydoconidia. The association of other phenotypic tests with culture in Tween 80 agar identified 95.8% of strains as C. albicans and 4.2% as C. dubliniensis. All 24 strains indicative of C. albicans and C. dubliniensis were confirmed by PCR as C. albicans.

16194 downloads Cited 4 times in SciELO

10.

Perfil clínico-epidemiológico dos pacientes portadores de paracoccidioidomicose no Serviço de Estomatologia do Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul
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Verli, Flaviana Dornela

; Marinho, Sandra Aparecida

; Souza, Sílvio Correa de

; Figueiredo, Maria Antonia Zancanaro de

; Yurgel, Liliane Soares

Revista da Sociedade Brasileira de Medicina Tropical

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may 2005, Volume 38 N. 3 Pages 234 - 237

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

No presente estudo, são descritas as características clínicas e epidemiológicas de 61 casos de paracoccidioidomicose, atendidos no Serviço de Estomatologia do Hospital São Lucas da PUCRS, no período de junho de 1976 a junho de 2004. O Rio Grande do Sul é considerado uma região endêmica da doença devido às condições eco-epidemiológicas para o desenvolvimento do fungo. Observou-se que a doença ocorreu em 58 (95%) homens e 3 (5%) mulheres, predominando a faixa etária de 40 a 59 anos (70,5%), e a profissão vinculada à agricultura em 27 (44,3%) pacientes. O hábito de fumar foi prevalente em 52 (85,3%) pacientes da amostra e muitos eram, também, etilistas. Todos os casos apresentavam manifestações estomatológicas, sendo que as lesões orais ocorreram predominantemente com aspecto ulcerado e moriforme, observadas em vários sítios anatômicos. As evidências radiográficas de lesões pulmonares estavam presentes em 32 (65,3%) radiografias avaliadas.

The aim of the article was to describe clinical and epidemiological features of 61 oral paracoccidioidomycosis cases from the Stomatology Department of São Lucas Hospital, analyzed from July 1976 to June 2004. The State of Rio Grande do Sul is an endemic region due to ecoepidemiologic conditions, that are favorable for the development of the yeast. Men are the most affected gender, with 58 (95%) affected compared to 3 (5%) women. Ii is most prevalent (70.5%) between 40 and 59 years of age. Agricultural labor was the most common occupation with 27/61 (44.3%) patients. Tobacco smoking was prevalent in 52 (85.3%) of the sample, and alcoholism was a frequent finding. All the patients showed stomatologic manifestations, with ulcers and mulberry-like stomatitis the most prevalent, these oral lesions were also observed in many anatomical sites. Alterations were present in 32 (65.3%) of the pulmonary radiographs.

4712 downloads Cited 7 times in SciELO

11.

Seqüela após redução de fratura zigomática empregando fio de Kirschner: relato de caso
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Vier, Fabiana Vieira

; Marinho, Sandra Aparecida

; Gabriel, João Guilherme

; Costa, Nilza Pereira da

; Veeck, Elaine Bauer

; Warszawsky, Denise

Radiologia Brasileira

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apr 2005, Volume 38 N. 2 Pages 157 - 160

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O presente trabalho objetiva apresentar e discutir um caso clínico em que o fio de Kirschner foi empregado para fixação do osso zigomático fraturado, não sendo removido após quatro semanas, como recomendado pela literatura, comportando-se como corpo estranho, e sendo então removido.

In this study we present and discuss a case of a patient in which a Kirschner wire was used for fixation of a fractured zygomatic bone. The Kirschner wire was not removed after four weeks as recommended in the literature but only after behaving as foreign body.

19529 downloads

12.

Parasitas intestinais em centros de educação infantil municipal de Lages, SC, Brasil
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Quadros, Rosiléia Marinho de

; Marques, Sandra

; Arruda, Andréia Aparecida Ribeiro

; Delfes, Patrícia Simone Wolff Rosa

; Medeiros, Íris Aparecida Azevedo

Revista da Sociedade Brasileira de Medicina Tropical

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oct 2004, Volume 37 N. 5 Pages 422 - 423

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Infecção por enteroparasitas foi avaliada em 200 crianças em idade escolar, residentes em Lages. A prevalência geral entre helmintos e protozoários foi de 70,5% com 61,4% no sexo masculino e 74,5% no feminino. Os parasitos mais prevalentes foram Ascaris lumbricoides (35%), Giardia lamblia (14%) e Trichuris trichiura (13%).

Two hundred chinldren from nursery schools in Lages, southern Brazil, were associated as to parasitic ibfections. The overall prevalence of helminths and protozoa was 70.5%, affecting 61.4% of male and 74.5% of female children. The most prevalent parasites were Ascaris lumbricoides (35%), Giardia lambia (14%) e Trichuris trichiura (13%).

9133 downloads Cited 4 times in SciELO

13.

EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
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Aparecida Marinho, Sandra

; Sala, Miguel Angel

; Lopes, Ruberval Armando

; de Moraes Grisi, Márcio Fernando

; Belém Novaes Jr., Arthur

; Scombatti de Souza, Sérgio Luis

; Taba Jr., Mário

International Journal of Morphology

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2003, Volume 21 N. 2 Pages 107 - 111

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: The effects of acetylsalicylic acid (ASA) on intrauterine growth restriction induced by maternal ethanol consumption were studied. A single intraperitoneal dose of ethanol (2.96 g/kg body weight), injected on the 10th day of pregnancy (PD10), significantly reduced maternal weight gain, fetal weight, amniotic fluid volume and umbilical cord length. Meanwhile, ethanol did not affect placental weight or litter size. A single intraperitoneal dose of ASA (200 mg/g body weight), injected on the PD10, did not modify maternal body weight gain, litter size, fetal and placental weights and amniotic fluid volume, but significantly diminished umbilical cord length. Intraperitoneal injections of either ASA (200 mg/g body weight) or ethanol (2.96 g/kg body weight) on the PD10, demonstrated that ASA antagonized, in part at least, the effects of ethanol on maternal weight gain, fetal weight, and amniotic fluid volume. Contrarily, ASA potentiated the effect of ethanol on umbilical cord length

Fueron estudiados los efectos del ácido acetilsalicílico (AAS) sobre la restricción de crecimiento intrauterino inducida por el consumo materno de etanol. Una única dosis intraperitoneal de etanol (2,96 g/kg de peso corporal), inyectada en el 10 día de preñez (PD10), disminuyó significativamente la ganancia de peso materno, peso fetal, volumen del líquido amniótico y longitud del cordón umbilical. En cambio, el etanol no afectó el peso de la placenta ni el tamaño de la nidada. Una única dosis intraperitoneal de AAS (200 mg/g de peso corporal), inyectada en el PD10, no modificó la ganancia de peso materno, tamaño de la nidada, los pesos fetal y placentario, ni el volumen del líquido amniótico, pero disminuyó significativamente la longitud del cordón umbilical. La inyección intraperitoneal de AAS (200 mg/g de peso corporal) y de etanol (2.96 g/kg de peso corporal) en el PD10, demostró que el AAS antagoniza, por lo menos en parte, los efectos del etanol sobre la ganancia de peso materno, peso fetal y volumen del líquido amniótico. Al contrario, el AAS potencializa el efecto del etanol sobre la longitud del cordón umbilical

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