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Irrigation depth and silicate fertilisation in green maize
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Fernandes, Chrislene Nojosa Dias

; Viana, Thales Vinícius de Araújo

; Fernandes, Carlos Newdmar Vieira

; Silva, Alexandre Reuber Almeida da

; Azevedo, Benito Moreira de

; Marinho, Albanise Barbosa

Revista Ciência Agronômica

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2022, Volume 53 elocation e20207517

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The successful use of irrigation depends on the adoption of efficient management, which in turn depends on determining the correct amount of irrigation water. Due to the water scarcity seen in recent years, there is an obvious need for strategies that would make it possible to reduce the amount of water applied to crops with no reduction in productivity. Among such strategies, the application of silicon, which is associated with several beneficial effects for the plant, can increase water use efficiency. The aim of the present work was to study irrigation-depth management versus silicon doses via foliar application in green maize under a semi-arid climate. The experiment was conducted from August to November 2017 in an area of the Federal Institute of Ceará, Iguatu Campus, Ceará, using the AG1051 hybrid. The experimental design was of randomised blocks, comprising split plots and four blocks. Five irrigation depths (50, 75, 100, 125 and 150% of the ETc) were evaluated in the plots and four doses of silicon (50, 100, 150 and 200% of the recommended dose) were evaluated in the subplots. The following growth variables were analysed 15, 30, 45, 60 and 75 days after sowing (DAS): leaf dry weight, stem dry weight, and total dry weight; the production variables, evaluated at 81 DAS, were ear diameter and ear length with no husks, ear weight with and with no husks, and productivity. The application of silicon had no significant effect on the variables, while the irrigation depths afforded linear growth for each variable, with the highest productivity (10,459.3 kg ha-1) obtained for the greatest irrigation depth of 600 mm (150%) of the ETc).

RESUMO O sucesso do uso da irrigação está condicionado a adoção de um manejo eficiente, fato dependente da determinação de uma correta lâmina. Em função da escassez hídrica enfrentada nos últimos anos, evidenciou-se a necessidade de estratégias que possibilitem a redução da quantidade de água aplicada às culturas, sem redução de produtividade, dentre essas, a aplicação de silício, associada a diversos efeitos benéficos para o vegetal, pode aumentar a eficiência do uso da água. Assim, objetivou-se estudar o manejo de lâminas de irrigação versus doses de silício, aplicadas via foliar, na cultura do milho verde, sob clima semiárido. O experimento foi conduzido na área do Instituto Federal do Ceará, Campus de Iguatu, CE, com o híbrido AG1051, de agosto a novembro de 2017. O delineamento experimental foi em blocos ao acaso com parcelas subdivididas, e quatro blocos. Nas parcelas avaliou-se cinco lâminas de irrigação (50, 75, 100, 125 e 150% da ETc) e nas subparcelas quatro doses de silício (50, 100, 150 e 200% do recomendado). As variáveis de crescimento, analisadas aos 15, 30, 45, 60 e 75 dias após a semeadura (DAS), foram: massa seca das folhas, do colmo e total; e as produtivas, avaliadas ao 81 DAS, foram: diâmetro e comprimento da espiga sem palha, massa da espiga com e sem palha e produtividade. A aplicação de silício não influenciou significativamente as variáveis, enquanto as lâminas proporcionaram crescimento linear para todas, com maior produtividade (10.459,3 kg ha-1), obtida para a maior lâmina de 600 mm (150% da ETc).

https://doi.org/10.5935/1806-6690.20220043

COVID-19 and isolation: Risks and implications in the scenario of new variants
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Dias, Viviane Maria de Carvalho Hessel

; Oliveira, Alexandre Ferreira

; Marinho, Ana Karolina Barreto Berselli

; Santos Ferreira, Carlos Eduardo dos

; Domingues, Carlos Eduardo Ferreira

; Fortaleza, Carlos Magno Castelo Branco

; Vidal, Claudia Fernanda de Lacerda

; Carrilho, Claudia Maria Dantas de Maio

; Pinheiro, Debora Otero Britto Passos

; de Assis, Denise Brandão

; Medeiros, Eduardo Alexandrino

; Morejón, Karen Mirna Loro

; Weissmann, Leonardo

; Michelin, Lessandra

; Carneiro, Marcelo

; Nogueira, Maria Dolores Santos da Purificação

; de Oliveira, Priscila Rosalba Domingos

; Buralli, Rafael Junqueira

; Stucchi, Raquel Silveira Bello

; Lins, Rodrigo Schrage

; Costa, Silvia Figueiredo

; Chebabo, Alberto

Brazilian Journal of Infectious Diseases

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2022, Volume 26 N. 5 elocation 102703

Abstract: En | Text: En | PDF: En

Abstract With the emergence of new variants of SARS-CoV-2, questions about transmissibility, vaccine efficacy, and impact on mortality are important to support decision-making in public health measures. Modifications related to transmissibility combined with the fact that much of the population has already been partially exposed to infection and/or vaccination, have stimulated recommendations to reduce the isolation period for COVID-19. However, these new guidelines have raised questions about their effectiveness in reducing contamination and minimizing impact in work environments. Therefore, a collaborative task force was developed to review the subject in a non-systematic manner, answering questions about SARS-CoV-2 variants, COVID-19 vaccines, isolation/quarantine periods, testing to end the isolation period, and the use of masks as mitigation procedures. Overall, COVID-19 vaccines are effective in preventing severe illness and death but are less effective in preventing infection in the case of the Omicron variant. Any strategy that is adopted to reduce the isolation period should take into consideration the epidemiological situation of the geographical region, individual clinical characteristics, and mask for source control. The use of tests for isolation withdrawal should be evaluated with caution, due to results depending on various conditions and may not be reliable.

https://doi.org/10.1016/j.bjid.2022.102703

Bixinoids Derived from Bixa orellana as a Potential Zika Virus Inhibitor Using Molecular Simulations. Antiviral Effect on the Zika Virus of Bixinoids
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Nogueira Sobrinho, Antonio Carlos

; Roberto, Caio Henrique Alexandre

; Lima, Danielle Malta

; Fonseca, Aluisio Marques da

; Marinho, Emmanuel Silva

Brazilian Archives of Biology and Technology

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2022, Volume 65 elocation e22210032

Abstract: En | Text: En | PDF: En

Abstract Zika fever is a viral infection of great relevance in public health, especially in tropic regions, in which there is a predominance of mosquitoes of the genus Aedes, vectors of the disease. Microcephaly in neonatal children and Guillain-Barré syndrome in adults can be caused by the action of the Zika virus (ZIKV). Non-structural proteins, such as NS2B, NS3 and NS5, are important pharmacological targets, due to their action in the life cycle. The absence of anti-Zika drugs raises new research, including prospecting for natural products. This work investigated the in silico antiviral activity of bixin and six other derived molecules against the Zika viral proteins NS2B-NS3 and NS5. The optimized structure was subjected to molecular docking to characterize the interaction between bixinoids and ZIKV non-structural proteins, where significant interactions were observed with amino acid residues in the catalytic site in each enzyme. These results suggest that bixin and ethyl bixin has the potential to interfere with the enzymatic activity of NS2B, NS3 and NS5, thus being an indication of being a promising anti-Zika agent.

https://doi.org/10.1590/1678-4324-2022210032

Factors associated with hospitalizations for Covid-19 in patients with rheumatoid arthritis: data from the Reumacov Brazil registry
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Gomides, Ana Paula Monteiro

; Albuquerque, Cleandro Pires de

; Mota, Licia Maria Henrique da

; Devidé, Guilherme

; Dias, Laiza Hombre

; Duarte, Angela Luzia Branco Pinto

; Giovelli, Raquel Altoé

; Karnopp, Thais Evelyn

; Lima, Hugo Deleon de

; Marinho, Adriana

; Oliveira, Marianne Schrader de

; Omura, Felipe

; Ranzolin, Aline

; Resende, Gustavo

; Ribeiro, Francinne Machado

; Ribeiro, Sandra Lúcia Euzébio

; Sacilotto, Nathália de Carvalho

; Santos, Wander Gonzaga dos

; Shinjo, Samuel Katsuyuki

; Studart, Samia Araujo de Sousa

; Teixeira, Flávia Patricia Sena

; Yazbek, Michel Alexandre

; Ferreira, Gilda Aparecida

; Monticielo, Odirlei A.

; Paiva, Eduardo

; Pileggi, Gecilmara Cristina Salviato

; Reis Neto, Edgard Torres dos

; Pinheiro, Marcelo de Medeiros

; Marques, Claudia D. L.

Advances in Rheumatology

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2022, Volume 62 elocation 13

Abstract: En | Text: En | PDF: En

Abstract Background: Patients using immunosuppressive drugs may have unfavorable results after infections. However, there is a lack of information regarding COVID 19 in these patients, especially in patients with rheumatoid arthritis (RA). Therefore, the aim of this study was to evaluate the risk factors associated with COVID 19 hospitalizations in patients with RA. Methods: This multicenter, prospective cohort study is within the ReumaCoV Brazil registry and included 489 patients with RA. In this context, 269 patients who tested positive for COVID 19 were compared to 220 patients who tested negative for COVID 19 (control group). All patient data were collected from the Research Electronic Data Capture database. Results: The participants were predominantly female (90.6%) with a mean age of 53 ±12 years. Of the patients with COVID 19, 54 (20.1%) required hospitalization. After multiple adjustments, the final regression model showed that heart disease (OR =4.61, 95% CI 1.06–20.02. P < 0.001) and current use of glucocorticoids (OR =20.66, 95% CI 3.09–138. P < 0.002) were the risk factors associated with hospitalization. In addition, anosmia was associated with a lower chance of hospitalization (OR =0.26; 95% CI 0.10–0.67, P < 0.005). Conclusion: Our results demonstrated that heart disease and the use of glucocorticoids were associated with a higher number of hospital admissions for COVID 19 in patients with RA. Trial registration: Brazilian Registry of Clinical Trials RBR 33YTQC.

https://doi.org/10.1186/s42358-022-00244-5

Paciente em Parada Cardiorrespiratória – É Possível a Realização de Implante Percutâneo de Valva Aórtica (TAVI) nesse Cenário?
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Soeiro, Alexandre de Matos

; Cardozo, Francisco Akira

; Guimarães, Patrícia Oliveira

; Pereira, Marcel Paula

; Souza, Paulo Vinícius Ramos

; Boros, Gustavo A. B.

; Veiga, Viviane Cordeiro

; Rojas, Samolon Soriano Ordinola

; Mangione, Fernanda Marinho

; Cristóvão, Salvador André Bavaresco

; Dutra, Gustavo Alexandre

; Salman, Adnan Ali

; Bettarello, Luiz Eduardo Loureiro

; Mangione, José Armando

Arquivos Brasileiros de Cardiologia

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aug 2021, Volume 117 N. 2 Pages 404 - 406

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20201097

Associação entre Escores de Risco Clínico (HEART, GRACE e TIMI) e Complexidade Angiográfica na Síndrome Coronária Aguda sem Elevação do Segmento ST
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Cedro, Alexandre Vianna

; Mota, Diandro Marinho

; Ohe, Louis Nakayama

; Timerman, Ari

; Costa, José Ribamar

; Castro, Laura de Siqueira

Arquivos Brasileiros de Cardiologia

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aug 2021, Volume 117 N. 2 Pages 281 - 287

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background: GRACE, TIMI and HEART scores have been previously validated to predict serious untoward events among patients with non-ST elevation acute coronary syndrome (Non-ST ACS). However, the ability of these scores to discriminate the angiographic complexity of coronary artery disease has not been clearly established. Objectives: We sought to evaluate the correlation between clinical scores (TIMI, GRACE and HEART) and the anatomical complexity assessed by SYNTAX score, among non-ST ACS patients undergoing cinecoronariography. Methods: Transversal cohort encompassing patients with diagnosis of Non-ST ACS referred to invasive stratification in our single center, between July 2018 and February 2019. Association between the scores was established by the Pearson's linear correlation test while the accuracy of the clinical scores versus SYNTAX score was determined with the ROC curve. Results: A total of 138 patients were enrolled. Median GRACE, TIMI and HEART scores were 97, 3 and 5, respectively, whereas the median SYNTAX was 8. There was a positive correlation between the SYNTAX and the HEART (ρ =0.29; p<0.01) and GRACE (ρ =0.18; p<0.01) scores, but the correlation with TIMI reached no statistical significance (ρ =0.15; p=0.08). The HEART score was also the one with the highest area under the curve to predict a SYNTAX ≥32 [HEART = 0.81 (IC95% 0.7-0.91). HEART> 4 presented 100% sensitivity, with 50% specificity; and GRACE> 139 showed 55% sensitivity and 97% specificity for high SYNTAX. Conclusion: The clinical scores presented a positive, although modest, association with the SYNTAX score. The combined use of HEART and GRACE offers good accuracy for detecting angiographic complexity.

Resumo Fundamentos: Os escores GRACE, TIMI e HEART foram validados para avaliar desfechos clínicos desfavoráveis no contexto da suspeita de síndrome coronária aguda sem elevação do segmento ST (SCASSST). No entanto, a associação entre os escores clínicos e a complexidade angiográfica ainda não está bem estabelecida. Objetivos: Descrever as características clínicas de pacientes com SCASSST admitidos em internação hospitalar para estratificação invasiva, a fim de avaliar a associação entre os escores clínicos (TIMI, GRACE e HEART) e a complexidade angiográfica, através do escore SYNTAX. Métodos: Estudo observacional incluindo pacientes com diagnóstico de SCA e admitidos no Instituto Dante Pazzanese de Cardiologia entre os meses de julho de 2018 e fevereiro de 2019. A associação entre os escores foi avaliada por correlações bivariadas e a sua acurácia pela área sob a curva (ASC) ROC. A significância estatística foi estabelecida em 5% (p < 0,05). Resultados: Um total de 138 pacientes foram diagnosticados com SCASSST. As medianas do GRACE, TIMI e HEART foram de 97, 3 e 5, respectivamente. A mediana do SYNTAX foi de 8. Foram observadas correlações positivas do SYNTAX com o HEART (ρ = 0,29; p < 0,01) e o GRACE (ρ = 0,18; p < 0,03). Em contrapartida, a correlação com o TIMI não atingiu significância estatística (ρ = 0,15; p = 0,08). O HEART foi o escore com a maior ASC para predizer SYNTAX > 32 [HEART = 0,81] (IC 95% 0,7-0,91). HEART > 4 apresentou sensibilidade de 100%, com especificidade de 50%, e GRACE > 139 sensibilidade de 55% e especificidade de 97% para SYNTAX alto. Conclusão: Os escores clínicos de risco apresentam associação modesta ao escore SYNTAX. O uso combinado do HEART e do GRACE, entretanto, oferece acurácia favorável para a detecção de complexidade angiográfica.

https://doi.org/10.36660/abc.20190417

CAD-FEA modeling and fracture resistance of bilayer zirconia crowns manufactured by the rapid layer technology
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Lima, Julia Magalhães Costa

; Costa, Anna Karina Figueiredo

; Anami, Lilian Costa

; Souza, Karina Barbosa

; Silva, Nathalia Ramos da

; Marinho, Renata Marques de Melo

; Borges, Alexandre Luis Souto

; Bottino, Marco Antonio

; Özcan, Mutlu

; Souza, Rodrigo Othávio Assunção

Brazilian Dental Journal

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jun 2021, Volume 32 N. 3 Pages 44 - 55

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract In the RLT (Rapid Layer Technology), veneering ceramic and framework are fabricated by computer-aided design/computer-aided manufacturing (CAD/CAM) and then cemented to obtain the restoration. This study aimed to evaluate the effect of the thickness of veneering ceramic manufactured by the RLT technique on the fracture resistance (FR) of bilayer crowns with zirconia frameworks. Twenty zirconia frameworks and twenty feldspathic posterior crowns with two different veneering ceramic occlusal thicknesses (1mm=TF1; 2mm=TF2) were manufactured using CAD/CAM system. The specimens were luted to an epoxy resin abutment with resin cement and mechanically cycled (200N and 4.5×105 Pa, 37°C, 2×106 cycles, 3Hz). The FR test was performed (10kN, 0.5mm/min), and the specimens were analyzed in a stereomicroscope. For the stress analysis (finite element analysis, FEA), a 10kN load was equal to the in vitro test, and the principal stress was evaluated. The FR data were analyzed by Student’s t-test and Weibull's analysis. The thickness influenced the FR of bilayer crowns. The FR was higher in the TF2 than in the TF1 group. The TF2 group presented the highest characteristic strength compared to the group TF1. The predominant type of failure was delamination. The FEA showed higher stress concentrations below the loading application point at the veneering cement interface in the 1-mm-thick model. The bilayer crowns manufactured using the approach of 2mm of veneering ceramic promoted higher FR compared to the group with 1mm veneering ceramic. Also, the FEA showed that the veneer ceramic thickness has an effect on stress distribution in zirconia-based bilayer crowns.

Resumo Na RLT (Rapid Layer Technology), a cerâmica de cobertura e infraestrutura são fabricados pelo Computer-Aided Design / Computer-Aided Manufacturing (CAD / CAM) e cimentados para obter a restauração. Este estudo teve como objetivo avaliar o efeito da espessura da cerâmica de cobertura fabricada pela técnica RLT na resistência à fratura (RF) de coroas bilaminadas com infraestrutura de zircônia. Vinte infraestruturas de zircônia e vinte coroas posteriores feldspáticas com duas espessuras oclusais da cerâmica de cobertura (1mm = TF1; 2mm = TF2) foram fabricadas usando o sistema CAD / CAM. Os espécimes foram cimentados em preparos de resina epóxi com cimento resinoso dual e ciclados mecanicamente (200N e 4,5×105 Pa, 37° C, 2×106 ciclos, 3Hz). O teste de RF foi realizado (10kN, 0,5mm / min) e, posteriormente, os espécimes foram analisados em estereomicroscópio. Para a análise de tensão (análise de elementos finitos, FEA), uma carga de 10kN foi aplicada igual ao teste in vitro, e a tensão principal foi avaliada. Os dados de RF foram analisados pelo teste t de Student e análise de Weibull. A espessura mostrou forte influência na RF das coroas bilaminadas. A RF foi maior em TF2 do que no grupo TF1. O grupo TF2 apresentou a maior resistência característica em relação ao grupo TF1. O tipo de falha predominante foi a delaminação. O FEA mostrou maiores concentrações de tensões abaixo do ponto de aplicação da carga, na interface cimento e cerâmica de cobertura no modelo de coroa de 1 mm de espessura. As coroas de bilaminadas confeccionadas com 2 mm de cerâmica de cobertura promoveram maior RF em comparação ao grupo com cerâmica de cobertura de 1 mm. Além disso, a FEA mostrou que a espessura da cerâmica de cobertura tem um efeito na distribuição de tensões em coroas bilaminadas à base de zircônia.

https://doi.org/10.1590/0103-6440202104163

Uma nota sobre o impacto das Unidades de Polícia Pacificadora (UPP) no município do Rio de Janeiro com o uso de controle sintético
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Maia, Iago de Azevedo Rocha

; Marinho, Alexandre

Revista Brasileira de Economia

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mar 2021, Volume 75 N. 1 Pages 15 - 28

Abstract: Pt | Text: Pt | PDF: Pt

Resumo O presente texto visa avaliar o efeito causado pelo programa das Unidades de Polícia Pacificadora (UPP) na taxa de homicídios no município do Rio de Janeiro. Foi utilizado o modelo de controle sintético para calcular esse efeito. O método permitiu criar um Rio de Janeiro sintético, ou seja, como seria o Rio de Janeiro caso o programa das UPP não tivesse sido implementado o que permitiu avaliar os resultados do programa. A implantação das UPP reduziu os homicídios na cidade do Rio de Janeiro no período de análise (1999–2016).

https://doi.org/10.5935/0034-7140.20210002

Anticipating the formation of guava seedlings using mini-grafting onto smaller-diameter clonal rootstocks
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Arantes, Mariana Barreto de Souza

; Marinho, Cláudia Sales

; Santos, Raudielle Ferreira dos

; Galvão, Sydney Pereira

; Vaz, Giuliana Pulitini

; Viana, Alexandre Pio

Revista Brasileira de Fruticultura

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2021, Volume 43 N. 2 elocation e-211

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The production of grafted seedlings requires longer periods of time. The technique of mini-grafting onto rootstocks previously obtained from herbaceous cuttings can guarantee the genetic fidelity of scion and rootstock and allows grafting onto smaller-diameter stems, accelerating the time required to obtain seedlings. The aim of this study was to anticipate the formation of ‘Paluma’ guava seedlings grafted onto clonal rootstocks with smaller-diameter stems. Treatments consisted of grafting onto rootstocks with five stem diameter classes. The experimental design was randomised blocks with three replicates and five seedlings per plot. Rootstocks were produced from cuttings of herbaceous branches of mother plants originating from crossing between P. guineense and P. cattleianum. Mini-grafts were obtained from a clonal ‘Paluma’ guava mini-garden . Seedlings grafted onto rootstocks with stem diameters from 3.7 to 10.3 mm presented the same success rate however the greatest seedling vigour was observed when grafted onto larger-diameter rootstocks. Grafting success and seedling height show that mini-grafting onto clonal rootstocks with diameters from 3.7 to 5.5 mm allows producing seedlings suitable for transplanting 300 days after cutting.

Resumo A produção de mudas enxertadas demanda maior período de tempo. A técnica da minigarfagem sobre porta-enxertos obtidos previamente por estaquia herbácea pode garantir a fidelidade genética da copa e do porta-enxerto e possibilitar a enxertia em caules de menor diâmetro, antecipando o período de obtenção dessas mudas. O objetivo deste trabalho foi a antecipação da formação da muda da goiabeira ‘Paluma’ enxertada sobre porta-enxertos clonais com caules de menor diâmetro. Os tratamentos foram constituídos pela enxertia sobre porta-enxertos com cinco classes de diâmetros do caule. O delineamento experimental adotado foi em blocos casualizados, com três repetições e cinco mudas por parcela. Os porta-enxertos foram produzidos por estaquia de ramos herbáceos de matrizes oriundas de cruzamento entre P. guineense x P. cattleianum. Os minigarfos foram obtidos de um minijardim clonal da goiabeira ‘Paluma’. Mudas enxertadas sobre porta-enxertos com diâmetros de caule entre 3,7 e 10,3 mm tiveram a mesma taxa de pegamento de enxertia; entretanto, o maior vigor das mudas foi observado quando estas foram enxertadas sobre porta-enxertos de maior calibre. O pegamento de enxertia e a altura das mudas indicam que a minigarfagem sobre porta-enxertos clonais, com diâmetros entre 3,7 e 5,5 mm, permite a produção de mudas aptas ao transplantio, aos 300 dias após o estaqueamento.

https://doi.org/10.1590/0100-29452021211

10.

Therapeutic itinerary of people with leprosy: paths, struggles, and challenges in the search for care
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Lima, Eliziane Oliveira de

; Silva, Maria Rocineide Ferreira da

; Marinho, Mirna Neyara Alexandre de Sá Barreto

; Alencar, Olga Maria de

; Pereira, Thayza Miranda

; Oliveira, Lúcia Conde de

; Anjos, Saiwori de Jesus Silva Bezerra dos

Revista Brasileira de Enfermagem

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2021, Volume 74 N. 1 elocation e20200532

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

ABSTRACT Objectives: to understand how the therapeutic itineraries of people affected by leprosy are processed. Methods: this is a descriptive, qualitative study, conducted in April 2018 in Barão de Grajaú in Maranhão, with interviews in the form of narratives of seven patients who had a late leprosy diagnosis. Results: the search for diagnosis is a major difficulty in accessing health services, resulting in a late diagnosis and, consequently, with the presence of visible deformities. It was noticed that the health units do not have a flow, nor protocols for comprehensive treatment, and these people are referred to a referral unit in another state to perform sputum smear microscopy. Final Considerations: leprosy control actions need reformulations that seek the relationship between operational activities, epidemiological indicators and risk factors, in accordance with the real needs of each region, thus highlighting the gaps evidenced in the therapeutic itineraries.

RESUMO Objetivos: compreender como se processam os itinerários terapêuticos das pessoas acometidas pela hanseníase. Métodos: estudo descritivo, qualitativo, realizado em abril de 2018, em Barão de Grajaú, no Maranhão, com entrevistas no formato de narrativas de sete pacientes que tiveram diagnóstico tardio de hanseníase. Resultados: a busca pelo diagnóstico se configura como uma grande dificuldade de acesso aos serviços de saúde, resultando no diagnóstico tardio e, consequentemente, na presença de deformidades visíveis. Percebeu-se que as unidades de saúde não possuem um fluxo nem protocolos para tratamento integral, sendo que essas pessoas são encaminhadas para unidade de referência em outro estado para a realização da baciloscopia. Considerações Finais: as ações de controle da hanseníase necessitam de reformulações que busquem a relação entre as atividades operacionais, indicadores epidemiológicos e os fatores de risco, em concordância com as reais necessidades de cada região, destacando-se, assim, as lacunas evidenciadas nos itinerários terapêuticos.

RESUMEN Objetivos: comprender cómo se procesan los itinerarios terapéuticos de las personas afectadas por la lepra. Métodos: estudio descriptivo, cualitativo, realizado en abril de 2018, en Barão de Grajaú, Maranhão, con entrevistas en forma de narrativas de siete pacientes con diagnóstico tardío de lepra. Resultados: la búsqueda del diagnóstico es una gran dificultad para acceder a los servicios de salud, resultando en un diagnóstico tardío y en presencia de deformidades visibles. Se notó que las unidades de salud no cuentan con un flujo ni protocolos de tratamiento integral, y estas personas son derivadas a una unidad de referencia en otro estado para realizar microscopía de baciloscopia de esputo. Consideraciones Finales: las acciones de control necesitan reformulaciones que busquen la relación entre las actividades operativas, los indicadores epidemiológicos y los factores de riesgo, de acuerdo con las necesidades reales de cada región, destacando las brechas que se evidencian en los itinerarios terapéuticos.

https://doi.org/10.1590/0034-7167-2020-0532

11.

Attitudes and perceptions of teachers and medical students regarding suicide
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Amorim, Maria Gardenia

; Kubrusly, Marcos

; Gomes, Sócrates Belém

; Plens, Isabella Cabral Marinho

; Rocha, Hermano Alexandre Lima

; Silva, Anamaria Cavalcante e

Revista Brasileira de Educação Médica

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2021, Volume 45 N. 4 elocation e214

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract: Introduction: The World Health Organization (WHO) estimates that there are around one million deaths by suicide a year worldwide, more than the total sum of deaths caused by wars and homicides, which results in one death every 40 seconds. Despite the existence of several scientific publications on suicide prevention, there have been studies showing that health professionals are not trained to adequately care for individuals at risk of suicide. Objective: This study aimed to understand the attitudes and perceptions of medical school students and teachers regarding suicide. Methods: This is a cross-sectional, descriptive study, with a quantitative and qualitative approach, approved by the Research Ethics Committee, which assessed a sample of 180 students attending the 8th and 11th semesters and 57 teachers from different semesters of the evaluated medical courses. The data were obtained by applying the Suicide Behavior Attitude Questionnaire (SBAQ), in addition to a sociodemographic questionnaire. The data were submitted to descriptive and analytical statistics. Results: Regarding professional capacity, the scores were low for both students (median 5.5) and teachers (median 5.25). Students who had seen someone exhibiting suicidal behavior (p = 0.002) and those attending the more advanced semesters (p = 0.04) felt more confident when treating patients at risk of suicide. There was a significant difference regarding the Right to Suicide factor among students who said they were religious (p = 0.001), as also among the teachers who attended religious services with a higher frequency (p = 0.02). Conclusions: We conclude that students and teachers have had little experience with suicide in the assessed medical courses, which contributes to low level of training and the feeling of insecurity, indicating the need to give more importance to the subject in the undergraduate medical school, aiming to allow the acquisition of knowledge and skills for a competent and preventive medical practice regarding suicide.

Resumo: Introdução: A estimativa da Organização Mundial da Saúde (OMS) é que haja cerca de um milhão de mortes por suicídio por ano no mundo, mais do que a soma total de mortes em guerras e homicídios, que resulta em uma morte a cada 40 segundos. Apesar da existência de diversas publicações científicas sobre a prevenção do suicídio, existem estudos que mostram que os profissionais de saúde não são capacitados para cuidar adequadamente de pessoas em risco de suicídio. Objetivo: Este estudo teve como objetivo compreender as atitudes e percepções de alunos e professores do curso de medicina em relação ao suicídio. Métodos: Trata-se de um estudo transversal, descritivo, com abordagem quantitativa e qualitativa, aprovado pelo Comitê de Ética em Pesquisa, que avaliou uma amostra de 180 alunos do 8º e 11º semestres e 57 professores de diferentes semestres dos cursos médicos avaliados. Os dados foram obtidos por meio da aplicação do Suicide Behavior Attitude Questionnaire (SBAQ), além de um questionário sociodemográfico. Os dados foram submetidos à estatística descritiva e analítica. Resultados: Em relação à capacidade profissional, as pontuações foram baixas tanto para alunos (mediana 5,5) quanto para professores (mediana 5,25). Alunos que viram alguém apresentando comportamento suicida (p = 0,002) e os que frequentavam o semestre mais avançado (p = 0,04) sentiram-se mais confiantes no atendimento de pacientes com risco de suicídio. Houve diferença significativa quanto ao fator Direito ao Suicídio entre os alunos que se disseram religiosos (p = 0,001), assim como entre os professores que frequentavam serviços religiosos com maior frequência (p = 0,02). Conclusões: Concluímos que alunos e professores tiveram pouca experiência com suicídio nos cursos de medicina avaliados, o que contribui para o baixo nível de formação e o sentimento de insegurança, indicando a necessidade de dar mais importância ao assunto na graduação em medicina, visando permitir a aquisição de conhecimentos e habilidades para uma prática médica preventiva e competente em relação ao suicídio.

https://doi.org/10.1590/1981-5271v45.4-20210299.ing

12.

Layered double hydroxides for controlled fluoride release
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CARDOSO, Clarissiane Serafim

; FREITAS, Johnnatan Duarte de

; SANTOS, Naile Roberta Lima dos

; ALMEIDA JÚNIOR, Alexandre

; BASÍLIO JÚNIOR, Irinaldo Diniz

; NASCIMENTO, Ticiano Gomes do

; GRILLO, Luciano Aparecido Meireles

; PORTO, Isabel Cristina Celerino de Moraes

; MARINHO, José Luis Gomes

; SANTOS, Grazielle Emanuella de Souza dos

; MEILI, Lucas

; SAMPAIO, Fábio Correia

; DORNELAS, Camila Braga

Brazilian Oral Research

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2021, Volume 35 elocation e104

Abstract: En | Text: En | PDF: En

Abstract This study aims to develop a nano-sized fluoridated layered double hydroxide (LDH)-based release system via hydrothermal treatment for the controlled delivery of fluoride (F-) ions in the oral environment. The synthesis of conventional LDH-type (C-LDH) precursor nanomaterials was conducted using a co-precipitation method at constant pH, and the nanoparticulate-LDH (N-LDH) was synthesized by a hydrothermal procedure. Fluoride LDH (F-LDH) products were obtained through indirect synthesis using the precursor ion-exchange technique by varying the agitation time (2 and 24 h) and temperature (25 and 40 °C) to produce 12 material samples. The materials were characterized by energy dispersive x-ray, hexamethyldisilazane, digital radiography x-ray, Fourier-transform infrared, thermogravimetric analysis, and scanning electron microscopy. Additionally, the F-release kinetic profile was evaluated for 21 d in neutral and acid media with mathematical model analysis. Products with varying F-quantities were obtained, revealing specific release profiles. In general, there was a higher F-release in the acid medium, with emphasis on F-LDH-8. Fluoride-LDH and controlled fluoride delivery was successfully obtained, proving the potential of these nanomaterials as alternative anti-caries agents.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0104

13.

COVID-19: challenges for dementia care and research
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Dourado, Marcia Cristina Nascimento

; Belfort, Tatiana

; Monteiro, Alexandre

; Lucena, Aline Tavares de

; Lacerda, Isabel Barbeito

; Gaigher, Julia

; Baptista, Maria Alice Tourinho

; Brandt, Michelle

; Kimura, Nathália Ramos

; Souza, Natalie de

; Gasparini, Paula

; Rangel, Rogéria

; Marinho, Valeska

Dementia & Neuropsychologia

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dec 2020, Volume 14 N. 4 Pages 340 - 344

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT. The COVID-19 pandemic has raised significant concerns about the management and care for people with dementia and their caregivers. In this context, this work will discuss how social isolation or social distancing caused by the pandemic may impact the clinical management of people with dementia, caregivers’ health, and dementia research. The pandemic disrupts all forms of social interaction and may increase the behavioral impairment of people with dementia. Regarding pharmacological treatment, telemedicine is an option, but the context of social isolation raises questions about how to manage people with dementia with lack of cognitive stimulation and non-pharmacological treatment. In addition, the impact of the pandemic on caregivers should be considered. There is some evidence that telephone counseling can reduce depressive symptoms of caregivers of people with dementia. In dementia research, social isolation imposes researchers to modify their study protocols in order to continue collecting data by developing remote tools to assess the participants such as electronic informed consent and online questionnaires and tests. Thus, there is an urgent need for the evaluation and refinement of interventions to address several cognitive, behavioral, and clinical aspects of the long-term impact of the pandemic in dementia.

RESUMO. A pandemia causada pelo COVID-19 desencadeia grandes preocupações sobre o manejo e cuidados com as pessoas com demência e seus cuidadores. Neste contexto, discutiremos como o isolamento social causado pela pandemia pode impactar o manejo clínico de pessoas com demência, a saúde do cuidador e a pesquisa sobre demência. A pandemia interrompe todas as formas de interação social e pode causar aumento do comprometimento dos sintomas neuropsiquiátricos nas pessoas com demência. Em relação ao tratamento farmacológico, a telemedicina é uma opção, mas o contexto de isolamento social levanta questões sobre como manejar as pessoas com demência com falta de estimulação cognitiva ou intervenções nãofarmacológicas. Além disso, o impacto da pandemia sobre os cuidadores deve ser considerado. Existem evidências de que o aconselhamento telefônico pode reduzir os sintomas depressivos dos cuidadores. Além disso, o isolamento social impõe que pesquisadores modifiquem seus protocolos de pesquisa com o objetivo de continuar coletando dados, através do desenvolvimento de ferramentas remotas para avaliar os participantes, como o consentimento livre e esclarecido eletrônico e questionários e testes online. Assim, há uma necessidade urgente de avaliação e refinamento das intervenções para abordar aspectos cognitivos, comportamentais e clínicos do impacto de longo prazo da pandemia na demência.

https://doi.org/10.1590/1980-57642020dn14-040002

14.

Lignin and stem flexibility in eucalyptus seedlings subjected to hardening
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Lima, Paulo Ricardo

; Malavasi, Ubirajara Contro

; Lopes, Maycom Marinho

; Dranski, João Alexandre Lopes

; Malavasi, Marlene de Matos

; Gurgacz, Flavio

; Borsoi, Augustinho

Ciência Florestal

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apr 2020, Volume 30 N. 2 Pages 352 - 366

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The objective of this work was to verify if hardening by stem bending and foliar spray of jasmonic acid (JA) induced lignification and if it altered the post-planting development. The experiment was initially conducted in a shade house following a completely randomized design with treatments as (T1) control; (T2) 2.0 μmol L-1 of JA; (T3) 4.0 μmol L-1 of JA; (T4) 6.0 μmol L-1 of JA; (T5) 8.0 μmol L-1 of JA; (T6) 20 stem bending; (T7) 40 stem bending and five replicates. At the end of the imposed treatments, we calculated the increments in height, stem diameter, number of leaves, root and shoot dry biomasses, as well as the lignin content of shoots and roots and the stem stiffness. Afterwards, seedlings were planted following a randomized block design with three seedlings per replicate. At 90 and 150 days after planting, we quantified increments in height and stem diameter. Treatments T5 and T6 showed higher bending strength (0.28885 and 0.3005 N cm-1, respectively). Seedlings submitted to doses above 6.0 μmol L-1 of JA (T5) and imposition of stem bending (T6 and T7) resulted in a higher stem lignin content. The smaller doses of JA (T2, T3 and T4) and 20 stem bending (T6) resulted in seedlings with a relative increase in diameter. The interpretation of path analysis showed weak multicollinearity, that is, the variables under study are not highly correlated and there was a greater direct correlation between the lignin content of the stem with the mean increase in height and diameter of the seedlings after planting.

Resumo O trabalho objetivou verificar se a rustificação por flexões caulinares e a pulverização foliar com ácido jasmônico (JA) induz lignificação e altera o desenvolvimento pós-plantio. O experimento iniciou em ambiente protegido seguindo um delineamento inteiramente ao acaso com sete tratamentos (T1) testemunha; (T2) 2,0 μmol L-1 de JA; (T3) 4,0 μmol L-1 de JA; (T4) 6,0 μmol L-1 de JA; (T5) 8,0 μmol L-1 de JA; (T6) 20 flexões; (T7) 40 flexões e cinco repetições. Ao final da aplicação dos tratamentos, avaliaram-se os incrementos na altura, no diâmetro do coleto e número de folhas, assim como o teor de lignina dos tecidos caulinares, das raízes e a rigidez flexural. Em seguida, as mudas rustificadas foram plantadas a campo em delineamento em blocos ao acaso com três mudas por repetição. Aos 90 e 150 dias, avaliaram-se os incrementos na altura e no diâmetro do caule. Mudas dos tratamentos T5 e T6 apresentaram maior resistência à curvatura (0,2885 e 0,3005 N cm-1, respectivamente). O teor de lignina no caule aumentou com aplicações de JA acima de 6,0μmol L-1 e imposição de flexões caulinares. As menores doses de JA (T2, T3 e T4) e o tratamento com 20 flexões caulinares (T6) resultaram em mudas com aumento no incremento no diâmetro do caule. A interpretação da análise de trilha demonstrou que houve aumento na rigidez do caule acompanhado com o aumento no teor de lignina e que estes possuem um maior efeito direto inversamente proporcional com o incremento médio em altura e com o diâmetro do caule após o plantio.

https://doi.org/10.5902/1980509833047

15.

Guava seedlings with rootstocks or interstocks and their reaction to salinity
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Souza, Alexandre Gomes de

; Marinho, Cláudia Sales

; Silva, Mírian Peixoto Soares da

; Carvalho, Waleska Soares Gomes

; Campos, Graziella Siqueira

; Pestana, Bruno Abreu

Bragantia

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mar 2020, Volume 79 N. 1 Pages 74 - 82

Abstract: En | Text: En | PDF: En

ABSTRACT The introduction of rootstocks for the guava has become necessary due to the advance of guava decline. Among them, Psidium spp. or their hybrids have been evaluated. In addition to disease resistance, tolerance to salinity must be evaluated in the new rootstocks. The aim of this study was to verify the effect of rootstocks and intergrafts on the mineral composition of Psidium spp. submitted to salt stress. The experiment was setup in a randomized block design, with the following treatments (scion/rootstock):P. guineense/P. cattleianum; P. guajava/P. guineense/P. cattleianum; P. guajava‘Paluma’/P. guajava; P. guajava ‘Paluma’/P. guineense; P. guajava ‘Cortibel 1’/P. guajava;P. guajava ‘Cortibel 1’/P. guineense; P. cattleianum (purple) and P. cattleianum (yellow), with three replications and three plants per plot. The plants underwent irrigation with saline solution, and the levels of macronutrients, micronutrients and sodium in the scion leaves were evaluated. As rootstock, P. cattleianum results in greater Na uptake, with higher levels in the leaves of the scions, leading to less tolerance to salt stress.

https://doi.org/10.1590/1678-4499.20190210

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