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ABSTRACT Soil erosion studies using rainfall simulators are generally expensive and time consuming. Thus, the aim of this study was to develop a prototype of an automatic runoff collector, capable of real-time quantifying runoff volume and soil loss in field trials using a rainfall simulator. The used sensors were chosen based on the type A uncertainty computed from different volumes of water and concentrations of sediment. Through specific programming, the runoff volume, sediment concentrations and the time of occurrence of the collections corresponding to each 200 cm³ of runoff were recorded on a micro-SD card. The robustness of the calibration and the programming developed were also evaluated in the Arduino Mega® 2560 microcontroller. The pressure (PSI.420) and turbidity (ST100) sensors were selected for developing the prototype, which was evaluated in the field with the InfiAsper rainfall simulator. Then, the data collected automatically by the sensors were compared to those obtained by manual measurement. The automatic runoff collector equipped with the PSI.420 and ST100 sensors has potential to obtain and store runoff data, and it was effective in evaluating the erosion process, generating mean errors of 12.25 and 13.16% for runoff volume and soil loss, respectively. The proposed prototype has a low cost of manufacture, in addition to optimizing the collection of erosion data in studies with rainfall simulators.

RESUMO Estudos relacionados à erosão do solo usando simuladores de chuva são geralmente onerosos e demorados. Assim, o objetivo deste estudo foi desenvolver um protótipo de coletor automático de escoamento superficial, capaz de quantificar em tempo real o volume de escoamento superficial e a perda de solo em ensaios de campo utilizando um simulador de chuva. Os sensores utilizados foram escolhidos com base na incerteza tipo A calculada a partir de diferentes volumes de água e concentrações de sedimentos. Por meio de programação específica, o volume da enxurrada, as concentrações de sedimentos e o tempo de ocorrência das coletas correspondentes a cada 200 cm³ de enxurrada foram registrados em um cartão micro-SD. A robustez da calibração e a programação desenvolvida também foram avaliadas no microcontrolador Arduino Mega® 2560. Os sensores de pressão (PSI.420) e de turbidez (ST100) foram selecionados para o desenvolvimento do protótipo, o qual foi avaliado em campo com o simulador de chuva InfiAsper. Em seguida, os dados coletados automaticamente pelos sensores foram comparados com os obtidos por medição manual. O coletor automático equipado com os sensores PSI.420 e ST100 tem potencial para obter e armazenar dados de escoamento, e foi eficiente na avaliação do processo erosivo, gerando erros médios de 12,25 e 13,16% para volume de escoamento e perda de solo, respectivamente. O protótipo proposto possui baixo custo de fabricação, além de otimizar a obtenção de dados de erosão em estudos com simuladores de chuva.

https://doi.org/10.1590/1807-1929/agriambi.v27n10p828-836

Multivariate analysis as a tool in the selection of sustainable melon agroecosystems in the semi-arid region
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Salviano, Alessandra M.

; Castro, José M. da C.

; Melo, Stefeson B. de

; Macedo, Márcia V. de

; Oliveira, Vitória R.

; Giongo, Vanderlise

Revista Caatinga

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sep 2023, Volume 36 N. 3 Pages 543 - 552

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Soil management systems, including tillage and green manuring, are important for the control of nematodes and for the sustainable production. The objective was to select, through multivariate analysis, sustainable agroecosystems for yellow melon cultivated under irrigated conditions in the Brazilian semi-arid region. The long-term experiment is set up in Argissolo Vermelho- Amarelo (Ultisol) with six multifunctional agroecosystems, composed of the combination of three mixtures of cover crops (1 - 75% legumes + 25% grasses and oilseeds; 2 - 25% legumes + 75% grasses and oilseeds and 3 - spontaneous vegetation) and two types of soil management (no tillage-NT and tillage-T). The purpose was to evaluate the nutritional status of plants, soil fertility, nematode population in roots and soil, and the yield. Data were analyzed with multivariate techniques, allowing the grouping of the agroecosystems based on their similarities and complexity of functions. The incorporation of plant residues to the soil reduces nematode population, but their maintenance on the surface allows the improvement of fertility and yield, even under larger nematode populations. The agroecosystems that associate the nonincorporation of residues from cover crops with larger species diversity in composition constitute the most complex model, allowing different environmental functionalities. Thus, it is recommended not to incorporate the plant residues, planting the melon seedlings directly in the straw. However, considering that the results obtained with the non-incorporation of spontaneous vegetation were similar to those obtained with the incorporation of commercial cover crops, it is concluded that this practice is also viable and adapted to the semi-arid conditions.

RESUMO Sistemas de manejo de solos, incluindo revolvimento e adubação verde, são importantes para o controle de nematoides e para a produção sustentável. Objetivou-se selecionar, por meio da análise multivariada, agroecossistemas sustentáveis para cultivo irrigado de melão amarelo no Semiárido brasileiro. As avaliações ocorreram num experimento de longa duração, com seis agroecossistemas multifuncionais, compostos pela combinação de três misturas de plantas de cobertura (1 - 75% leguminosas + 25% gramíneas e oleaginosas; 2 - 25% leguminosas + 75% gramíneas e oleaginosas e 3 - vegetação espontânea) e dois tipos de manejo do solo (sem e com revolvimento). Avaliaram-se o estado nutricional das plantas, a fertilidade do solo, as populações de nematoides nas raízes e no solo e a produtividade da cultura. Os dados foram submetidos às técnicas de análises multivariadas, permitindo agrupar os agroecossistemas por semelhanças e complexidade das suas funções. A incorporação dos resíduos vegetais ao solo reduz a população de nematoides, mas sua manutenção na superfície permite melhorar a fertilidade e alcançar boas produtividades, mesmo sob maior população de nematoides. Os agroecossistemas que associam o não revolvimento dos resíduos vegetais das plantas de cobertura com maior diversidade de espécies na composição é o modelo considerado mais complexo, permitindo diferentes funcionalidades ambientais. Assim, recomenda-se não incorporar os resíduos vegetais, transplantando as mudas de meloeiro diretamente sobre a palhada. No entanto, considerando que os resultados obtidos com a não incorporação da vegetação espontânea foram semelhantes à incorporação das plantas de cobertura comerciais, conclui-se que esta prática também é viável e adaptada às condições semiáridas.

https://doi.org/10.1590/1983-21252023v36n307rc

Facile synthesis, structure, and battery-type behavior of graphene oxides
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Silva, J. M. D.

; Fenandes, F. P. M.

; Silva, M. de O.

; Maraschin, T. G.

; Ferreira, L. S.

; Macedo, D. A.

; Silva, L. B. da

; Fim, F. de C.

Cerâmica

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apr 2023, Volume 69 N. 390 Pages 161 - 171

Abstract: En | Text: En | PDF: En

Abstract Graphene oxide (GO) is one of the main precursors for the production of graphene and other graphene-based materials. We report a simple, safe, and fast synthesis method to obtain graphene oxide as a functional material for battery-type electrodes. Washing and lyophilization processes were performed to evaluate their effects on exfoliation and removal of functional groups from graphene sheets. Sample GO1 consisted of a 10-layer stack of oxidized graphene, while sample GO2 had 8 stacked layers. The difference between them was an extra washing and lyophilization process in the GO2 sample. The electrochemical performance of graphene oxide-based electrodes, classified as battery-type, indicated an improved specific capacity of 10.15 C.g-1 for GO1 against 4.55 C.g-1 for GO2 at a specific current of 0.5 A.g-1. This superior battery-type behavior of the GO1 electrode, also confirmed by electrochemical impedance spectroscopy, was most likely due to a higher degree of oxygenated groups on its surface, as shown by energy dispersive spectroscopy (EDS) and Fourier transform infrared spectroscopy (FTIR) studies.

https://doi.org/10.1590/0366-69132023693903474

Amazonian Fruit Mari-Mari (Cassia leiandra Benth.): Identification of Flavonoids and Antioxidant, Antimicrobial and Antiproliferative Properties
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Souza, Mayane P. de

; Sá, Ingrity Suelen C.

; Freitas, Flávio Augusto de

; Souza, Afonso D. L. de

; Nunomura, Sergio M.

; Muniz, Magno P.

; Pereira, Ana Paula R.

; Augusto, Bianca O.

; Gomes, Giovana B.

; Perdomo, Renata T.

; Macedo, Maria Lígia R.

; Weber, Simone S.

; Nunomura, Rita de Cassia S.

Journal of the Brazilian Chemical Society

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mar 2023, Volume 34 N. 3 Pages 325 - 332

Abstract: En | Text: En | PDF: En

Mari-mari (Cassia leiandra Benth.) is an Amazonian native fruit that is highly appreciated in the northern region of Brazil, but there are few studies regarding its chemical composition and/or biological properties. A phytochemical study was conducted on the extracts of the pulp, peel and seeds; and their antioxidant, cytotoxic and antimicrobial potential were also determined. Methanol and acetone extracts from different fruit parts were subjected to total phenolic, 2,2-diphenyl-1 picrylhydrazyl (DPPH) radical scavenging and FeIII reducing capacity (FRAP) assays. From the peel extracts, the engeletin and astilbin could also be isolated and characterized based on nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. A quantification using ultra-fast liquid chromatography of acetone dry crude extracts (DCE) of the peel showed that engeletin was the main compound (532.77 mg g-1 DCE). Astilbin content was also determined (131.53 mg g-1 DCE). The antibacterial and antiproliferative activities were evaluated and the methanol extract of the peel showed higher growth inhibition activity against all tested bacteria. Engeletin showed a relevant antimicrobial effect against Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Acetone and methanol peel extracts exhibited a relevant inhibitory effect on the proliferation of breast carcinoma cells (MCF-7), with no toxicity to the normal cell line (NIH/3T3).

https://doi.org/10.21577/0103-5053.20220111

Tailoring the properties of Y2O3 via synthesis parameters varied during the PVA-assisted sol-gel route YO Y O Y2O PVAassisted PVA assisted solgel sol gel
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Carvalho, J. C. C.

; Bispo, G. F. C.

; Lilge, T. S.

; Bezerra, C. S.

; Andrade, A. B.

; Macedo, Z. S.

; Valerio, M. E. G.

Cerâmica

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jan 2023, Volume 69 N. 389 Pages 48 - 53

Abstract: En | Text: En | PDF: En

Abstract The effect of synthesis parameters on the microstructural behavior and morphology during the yttrium oxide (Y2O3) formation is reported. Y2O3 crystals were produced by a modified sol-gel route assisted by polyvinyl alcohol solution varying the calcination temperature and solution pH. The crystalline phase formation was investigated using X-ray powder diffraction combined with the Rietveld refinement method. The microstructural properties were analyzed by using the Williamson-Hall formalism. The calcination temperature followed the thermal events observed in the differential thermal analysis combined with the thermogravimetric analysis of the precursor xerogel. It was seen that the combination of PVA and pH variation can be used to minimize the calcination time and temperature. The morphological analysis showed samples with different sizes and appearances depending on pH and calcination temperature. Therefore, it was shown that the parameters in the synthesis process can be used to tailor the properties of Y2O3, such as crystallite size, degree of structural ordering, and morphology, and consequently, improve the desired application. YO Y O (Y2O3 reported Y2O solgel sol gel Xray X ray method WilliamsonHall Williamson Hall formalism xerogel Therefore size ordering consequently application (Y2O

https://doi.org/10.1590/0366-69132023693893425

Rediscovery of Uzelothrips scabrosus Hood, 1952, a recent representative of a basal Thysanoptera (Arthropoda: Insecta) lineage, in Brazil
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Macedo, J. M.

; Alencar, A. R. S.

; Silva, L. M. R.

; Silva, N. M. O.

; Lima, E. F. B.

Brazilian Journal of Biology

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2023, Volume 83 elocation e251434

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1519-6984.251434 90 downloads

Study of Surface Modification of Niobium Caused by Nitriding and Cathodic Cage Deposition
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Macedo, Francisco R. C.

; Monção, Renan M.

; Queiroz, José C. A.

; Libório, Maxwell S.

; Costa, José A. P.

; Rossino, Luciana S.

; Danelon, Miguel R.

; Feitor, Michelle C.

; Costa, Thércio H. C.

; Sousa, Rômulo R. M.

Materials Research

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2023, Volume 26 elocation e20220613

Abstract: En | Text: En | PDF: En

In this work, plasma nitriding (PN) and cathode cage plasma deposition (CCPN) treatments were carried out with temperatures of 400 and 450 °C to evaluate the modifications caused on the surface of pure niobium samples. XRD, SEM, Vickers microhardness, and sphere-disk analyses were used to characterize the coatings’ composition, morphology, hardness, and wear resistance. The results showed that the treated samples increased hardness and wear resistance, with the sample submitted to CCPN at 450 °C presenting the best tribological behavior.

https://doi.org/10.1590/1980-5373-mr-2022-0613

Salivary protein candidates for biomarkers of oral disorders in people with a crack cocaine use disorder
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CHAIBEN, Cassiano Lima

; MACEDO, Nayara Flores

; BATISTA, Thiago Beltrami Dias

; PENTEADO, Carlos Antonio Schaffer

; VENTURA, Talita M. O.

; DIONIZIO, Aline

; SOUZA, Paulo Henrique Couto

; BUZALAF, Marília Afonso Rabelo

; AZEVEDO-ALANIS, Luciana Reis

Journal of Applied Oral Science

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2023, Volume 31 elocation e20220480

Abstract: En | Text: En | PDF: En

Abstract The use of cocaine and its main derivative, crack, can cause some systemic effects that may lead to the development of some oral disorders. Objective To assess the oral health of people with a crack cocaine use disorder and identify salivary protein candidates for biomarkers of oral disorders. Methodology A total of 40 volunteers hospitalized for rehabilitation for crack cocaine addiction were enrolled; nine were randomly selected for proteomic analysis. Intraoral examination, report of DMFT, gingival and plaque index, xerostomia, and non-stimulated saliva collection were performed. A list of proteins identified was generated from the UniProt database and manually revised. Results The mean age (n=40) was 32 (±8.88; 18–51) years; the mean DMFT index was 16±7.70; the mean plaque and gingival index were 2.07±0.65 and 2.12±0.64, respectively; and 20 (50%) volunteers reported xerostomia. We identified 305 salivary proteins (n=9), of which 23 were classified as candidate for biomarkers associated with 14 oral disorders. The highest number of candidates for biomarkers was associated with carcinoma of head and neck (n=7) and nasopharyngeal carcinoma (n=7), followed by periodontitis (n=6). Conclusions People with a crack cocaine use disorder had an increased risk of dental caries and gingival inflammation; less than half had oral mucosal alterations, and half experienced xerostomia. As possible biomarkers for 14 oral disorders, 23 salivary proteins were identified. Oral cancer and periodontal disease were the most often associated disorders with biomarkers.

https://doi.org/10.1590/1678-7757-2022-0480

Posicionamento sobre Doença Isquêmica do Coração – A Mulher no Centro do Cuidado – 2023
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Oliveira, Gláucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Rassi, Daniela do Carmo

; Bragança, Érika Olivier Vilela

; Moura, Lidia Zytynski

; Arrais, Magaly

; Campos, Milena dos Santos Barros

; Lemke, Viviana Guzzo

; Avila, Walkiria Samuel

; Lucena, Alexandre Jorge Gomes de

; Almeida, André Luiz Cerqueira de

; Brandão, Andréa Araujo

; Ferreira, Andrea Dumsch de Aragon

; Biolo, Andreia

; Macedo, Ariane Vieira Scarlatelli

; Falcão, Breno de Alencar Araripe

; Polanczyk, Carisi Anne

; Lantieri, Carla Janice Baister

; Marques-Santos, Celi

; Freire, Claudia Maria Vilas

; Pellegrini, Denise

; Alexandre, Elizabeth Regina Giunco

; Braga, Fabiana Goulart Marcondes

; Oliveira, Fabiana Michelle Feitosa de

; Cintra, Fatima Dumas

; Costa, Isabela Bispo Santos da Silva

; Silva, José Sérgio Nascimento

; Carreira, Lara Terra F.

; Magalhães, Lucelia Batista Neves Cunha

; Matos, Luciana Diniz Nagem Janot de

; Assad, Marcelo Heitor Vieira

; Barbosa, Marcia M.

; Silva, Marconi Gomes da

; Rivera, Maria Alayde Mendonça

; Izar, Maria Cristina de Oliveira

; Costa, Maria Elizabeth Navegantes Caetano

; Paiva, Maria Sanali Moura de Oliveira

; Castro, Marildes Luiza de

; Uellendahl, Marly

; Oliveira Junior, Mucio Tavares de

; Souza, Olga Ferreira de

; Costa, Ricardo Alves da

; Coutinho, Ricardo Quental

; Silva, Sheyla Cristina Tonheiro Ferro da

; Martins, Sílvia Marinho

; Brandão, Simone Cristina Soares

; Buglia, Susimeire

; Barbosa, Tatiana Maia Jorge de Ulhôa

; Nascimento, Thais Aguiar do

; Vieira, Thais

; Campagnucci, Valquíria Pelisser

; Chagas, Antonio Carlos Palandri

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 7 elocation e20230303

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230303

10.

Comparing spacings of Anadenanthera peregrina (L.) Speg stand: response in biomass and carbon stock above and below ground
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Souza, Paulo Henrique de

; Caldeira, Marcos Vinicius Winckler

; Delarmelina, William Macedo

; Trazzi, Paulo André

; Paula, Ranieri Ribeiro

; Momolli, Dione Richer

; Moreau, Julia Siqueira

; Gomes, Gabriel Soares Lopes

; Gomes, Robert

; Sanquetta, Carlos Roberto

Revista Ambiente & Água

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2023, Volume 18 elocation e2919

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Forests play a crucial role in the global carbon cycle. Among the factors that can affect carbon stocks in forest stands, planting spacing stands out. This study verified the effect of spacing on biomass and carbon stock in a stand of Anadenanthera peregrina (L.) Speg at 56 months of age. They were planted with 3 x 2 m, 3 x 3 m, 4 x 3 m, 4 x 4 m and 5 x 5 m spacings. The biomass of the above-ground compartments (stem, branches, leaves and bark) and root biomass was quantified, totalling 16.42 and 6.68 Mg ha-1, respectively. The largest amount of biomass and carbon stock occurred in the denser spacings. Total biomass was twice as large at 3 x 2 m spacing compared to 5 x 5 m spacing. The root biomass represented 40.93% of the total biomass. The order of participation of the components in the total aboveground biomass was branches (44.99%), stem (40.77%), leaves (13.99%) and bark (4.90%). The denser spacings (3 x 2 m and 3 x 3 m) showed higher values of biomass and carbon stock than the wide spacings (4 x 3 m, 4 x 4 m and 5 x 5 m). There was no effect of planting spacing on carbon stock in necromass and soil.

Resumo As florestas desempenham um importante papel no ciclo do carbono. Dentre os fatores que podem afetar os estoques de carbono nos povoamentos florestais, o espaçamento de plantio tem grande relevância. O objetivo foi verificar o efeito do espaçamento na biomassa e no estoque de carbono em um povoamento de Anadenanthera peregrina (L.) Speg aos 56 meses de idade. O povoamento foi implantado nos espaçamentos 3 x 2 m, 3 x 3 m, 4 x 3 m, 4 x 4 m e 5 x 5 m. Quantificou-se a biomassa dos compartimentos acima do solo (madeira, galhos, folhas e casca) e da raiz, totalizando 16,42 e 6,68 Mg ha-1, respectivamente. A maior quantidade de biomassa e estoque de carbono ocorreu nos menores espaçamentos. A biomassa total foi duas vezes maior no espaçamento de 3 x 2 m em comparação com o espaçamento de 5 x 5 m. A biomassa abaixo do solo representou 40,93% da biomassa total. A ordem de participação dos componentes na biomassa aérea total foi galhos (44,99%), madeira (40,77%), folhas (13,99%) e casca (4,90%). Os espaçamentos mais densos (3 x 2 e 3 x 3 m) apresentaram maiores valores de biomassa e estoque de carbono do que os espaçamentos mais amplos (4 x 3 m, 4 x 4 m e 5 x 5 m). Não houve efeito do espaçamento de plantio sobre o estoque de carbono na necromassa e no solo.

https://doi.org/10.4136/ambi-agua.2919

11.

Determination of Trifloxystrobin in Soy Grape Juice and Natural Water by Photo-Induced Fluorescence and High-Performance Liquid Chromatography
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Almeida, Joseany M. S.

; Macedo, Rosana C.

; Cunha, Alessandra L. M. C. da

; Toloza, Carlos A. T.

; Aucélio, Ricardo Q.

Journal of the Brazilian Chemical Society

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2023, Volume 34 N. 12 Pages 1877 - 1886

Abstract: En | Text: En | PDF: En

A fluorescent (340/380 nm) photochemical product, identified at m/z 206 by mass spectrometry was obtained by photo-derivatization (15 s ultraviolet exposure) in water/acetonitrile 10/90 v/v. The photoproduct was used for indirect determination of trifloxystrobin in water and soy grape juice by high-performance liquid chromatography and fluorescence detection. Separation was made under isocratic conditions (acetonitrile/water 70/30% v/v, at 1.0 mL min 1 and 35 ºC) with trifloxystrobin photo-derivative eluting at 3.2 min. The influence of ultraviolet exposure was evaluated in short and long terms with photoproduct showing stability up to 120 min after 15 s of ultraviolet exposure. The limit of detection was 57 µg L-1 in water (87-109% recoveries). For soy grape juice, dispersive liquid-liquid micro-extraction was used to clean up and for pre-concentration (limit of detection of 9.5 µg kg 1 and 93-101% recoveries) attending to the maximum residue limits for citrus juices established by regulatory agencies. Potential interference by triazoles was evaluated.

https://doi.org/10.21577/0103-5053.20230080

12.

Effects of ortho-eugenol on anxiety, working memory and oxidative stress in mice
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Godoy, R.

; Macedo, A. B.

; Gervazio, K. Y.

; Ribeiro, L. R.

; Lima, J. L. F.

; Salvadori, M. G. S. S.

Brazilian Journal of Biology

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2023, Volume 83 elocation e271785

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Ortho-eugenol is a synthetic derivative from eugenol, the major compound of clove essential oil, which has demonstrated antidepressant and antinociceptive effects in pioneering studies. Additionally, its effects appear to be dependent on the noradrenergic and dopaminergic systems. Depression and anxiety disorders are known to share a great overlap in their pathophysiology, and many drugs are effective in the treatment of both diseases. Furthermore, high levels of anxiety are related to working memory deficits and increased oxidative stress. Thus, in this study we investigated the effects of acute treatment of ortho-eugenol, at 50, 75 and 100 mg/kg, on anxiety, working memory and oxidative stress in male Swiss mice. Our results show that the 100 mg/kg dose increased the number of head-dips and reduced the latency in the hole-board test. The 50 mg/kg dose reduced malondialdehyde levels in the prefrontal cortex and the number of Y-maze entries compared to the MK-801-induced hyperlocomotion group. All doses reduced nitrite levels in the hippocampus. It was also possible to assess a statistical correlation between the reduction of oxidative stress and hyperlocomotion after the administration of ortho-eugenol. However, acute treatment was not able to prevent working memory deficits. Therefore, the present study shows that ortho-eugenol has an anxiolytic and antioxidant effect, and was able to prevent substance-induced hyperlocomotion. Our results contribute to the elucidation of the pharmacological profile of ortho-eugenol, as well as to direct further studies that seek to investigate its possible clinical applications.

Resumo Ortho-eugenol é um derivado sintético do eugenol, composto principal do óleo essencial de cravo, que demonstrou efeitos antidepressivos e antinociceptivos em estudos pioneiros. Além disso, seus efeitos parecem ser dependentes dos sistemas noradrenérgico e dopaminérgico. Sabe-se que os transtornos de depressão e ansiedade compartilham uma grande sobreposição em sua fisiopatologia, e muitas drogas são eficazes no tratamento de ambas as doenças. Além disso, altos níveis de ansiedade estão relacionados a déficits de memória de trabalho e aumento do estresse oxidativo. Assim, o presente estudo investigou os efeitos do tratamento agudo de orto-eugenol, nas doses de 50, 75 e 100 mg/kg, na ansiedade, memória de trabalho e estresse oxidativo em camundongos Swiss machos. Nossos resultados mostram que a dose de 100 mg/kg aumentou o número de mergulhos e reduziu a latência no teste da placa perfurada. A dose de 50 mg/kg reduziu os níveis de malondialdeído no córtex pré-frontal e o número de entradas no labirinto em Y em comparação com o grupo de hiperlocomoção induzida por MK-801. Todas as doses reduziram os níveis de nitrito no hipocampo. Também foi possível avaliar uma correlação estatística entre a redução do estresse oxidativo e a hiperlocomoção após a administração do orto-eugenol. No entanto, o tratamento agudo não foi capaz de prevenir os déficits de memória de trabalho. Portanto, o presente estudo mostra que o orto-eugenol tem efeito ansiolítico e antioxidante, sendo capaz de prevenir a hiperlocomoção induzida pela substância. Nossos resultados contribuem para a elucidação do perfil farmacológico do orto-eugenol, bem como para direcionar novos estudos que busquem investigar suas possíveis aplicações clínicas.

https://doi.org/10.1590/1519-6984.271785

13.

First of report of occurrence and damage of Synoeca cyanea (Hymenoptera: Vespidae) on Mangifera indica L. in Brazil Hymenoptera (Hymenoptera Vespidae L
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Rocha, E. A. A.

; Silva, L. F.

; Fernandes, M. E. S.

; Macedo, A. F.

; Soares, C. S.

; Pereira, R. C.

; Fernandes, F. L.

Brazilian Journal of Biology

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2023, Volume 83 elocation e275126

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1519-6984.275126

14.

Posicionamento sobre a Saúde Cardiovascular nas Mulheres – 2022
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Oliveira, Glaucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Marques-Santos, Celi

; Costa, Maria Elizabeth Navegantes Caetano

; Carvalho, Regina Coeli Marques de

; Freire, Cláudia Maria Vilas

; Magalhães, Lucelia Batista Neves Cunha

; Hajjar, Ludhmila Abrahão

; Rivera, Maria Alayde Mendonça

; Castro, Marildes Luiza de

; Avila, Walkiria Samuel

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Lantieri, Carla Janice Baister

; Polanczyk, Carisi Anne

; Albuquerque, Carlos Japhet da Matta

; Born, Daniel

; Falcheto, Eduardo Belisário

; Bragança, Érika Olivier Vilela

; Braga, Fabiana Goulart Marcondes

; Colombo, Fernanda M. Consolim

; Jatene, Ieda Biscegli

; Costa, Isabela Bispo Santos da Silva

; Rivera, Ivan Romero

; Scholz, Jaqueline Ribeiro

; Melo Filho, José Xavier de

; Santos, Magaly Arrais dos

; Izar, Maria Cristina de Oliveira

; Azevedo, Maria Fátima

; Moura, Maria Sanali

; Campos, Milena dos Santos Barros

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rizk, Stéphanie Itala

; Rodrigues, Thais de Carvalho Vieira

; Salim, Thaís Rocha

; Lemke, Viviana de Mello Guzzo

Arquivos Brasileiros de Cardiologia

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nov 2022, Volume 119 N. 5 Pages 815 - 882

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220734

15.

[SciELO Preprints] - Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
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Marin-Neto, José Antonio Rassi Jr., Anis Moraes Oliveira, Gláucia M. Lemos Correia, Luís Claudio Novaes Ramos Jr., Alberto Hasslocher-Moreno, Alejandro Marcel Luquetti Ostermayer, Alejandro Sousa, Andréa Silvestre de Amato Vincenzo de Paola, Angelo Sobral de Sousa, Antonio Carlos Pinho Ribeiro, Antonio Luiz Correia Filho, Dalmo Moraes de Souza, Dilma do Socorro Cunha-Neto, Edecio J. A. Ramires, Felix Bacal, Fernando Pereira Nunes, Maria do Carmo Martinelli Filho, Martino Ibrahim Scanavacca, Maurício Magalhães Saraiva, Roberto Alves de Oliveira Júnior, Wilson M. Lorga-Filho, Adalberto de Jesus Benevides de Almeida Guimarães, Adriana Lopes Latado Braga, Adriana Sarmento de Oliveira, Adriana V. L. Sarabanda, Alvaro Yecê das Neves Pinto, Ana Assis Lopes do Carmo, André Schmidt, André Costa, Andréa Rodrigues da Ianni, Barbara Maria Markman Filho, Brivaldo Eduardo Rochitte, Carlos Thé Macedo, Carolina Mady, Charles Chevillard, Christophe Bittencourt das Virgens, Cláudio Marcelo Nery de Castro, Cleudson De Paoli de Carvalho Britto, Constança Felícia Pisani, Cristiano do Carmo Rassi, Daniela C. Sobral Filho, Dario Rodrigues Almeida, Dirceu A. Bocchi, Edimar T. Mesquita, Evandro de Souza Nogueira Sardinha Mendes, Fernanda Pereira, Francisca Tatiana Sperandio da Silva, Gilberto Marcelo de Lima Peixoto, Giselle Glotz de Lima, Gustavo H. Veloso, Henrique Turin Moreira, Henrique Bellotti Lopes, Hugo Masciarelli Francisco Pinto, Ibraim Pinto Dias, João Carlos Bemfica, João Marcos Silva-Nunes, João Paulo Soares Barreto-Filho, José Augusto Kerr Saraiva, José Francisco Lannes-Vieira, Joseli Menezes Oliveira, Joselina Luzia V. Armaganijan, Luciana Martins, Luiz Cláudio C. Sangenis, Luiz Henrique Barbosa, Marco Paulo Almeida-Santos, Marcos Antônio Simões, Marcos Vinicius Shikanai-Yasuda, Maria Aparecida Vieira Moreira, Maria da Consolação Higuchi, Maria de Lourdes Costa Monteiro, Maria Rita de Cássia Felix Mediano, Mauro Felippe Maia Lima, Mayara T. Oliveira, Maykon Moreira Dias Romano , Minna Nitz, Nadjar de Tarso Jorge Medeiros, Paulo Vieira Alves, Renato Alkmim Teixeira, Ricardo Coury Pedrosa, Roberto Aras, Roque Morais Torres, Rosália dos Santos Povoa, Rui Manoel Rassi, Sérgio Gabriel Salles Xavier, Sérgio Marinho Martins Alves , Silvia B. N. Tavares, Suelene Lima Palmeira, Swamy da Silva Junior, Telêmaco Luiz da Rocha Rodrigues, Thiago Madrini Junior, Vagner Maia da Costa , Veruska Dutra, Walderez

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Publication date: 2022-10-11

Abstract: En Pt

This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.nbsp; Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities. nbsp; Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.nbsp; The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.nbsp; The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.nbsp; nbsp;nbsp; Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.

Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou. A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica. Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas. A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica. A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.nbsp;nbsp;nbsp; Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.nbsp;

https://doi.org/10.1590/SciELOPreprints.4820

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