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ABSTRACT Purpose To develop a guide for the preparation of speech-language reports of implanted children to be shared among speech-language pathologists of cochlear implant (CI) services and rehabilitation professionals. Methods The Delphi method was used to select the relevant and fundamental items that should be included in the two versions proposed for the guide: Guide 1 - Speech-language reports provided by the CI services to rehabilitators, and Guide 2 - Speech-language reports provided by the rehabilitators to CI services. Twenty-one speech therapists specialized and with experience in cochlear implants and auditory rehabilitation participated in the discussion and judgment of the items during the selection rounds. Consensus was considered when the item reached agreement equal to or greater than 80% among participants, being selected to compose the two guides. Results After the two rounds, 21 items from Guide 1 reached consensus among therapists, that is, more than 80% of them agreed that these items should be present in the report sent by the CI service. For Guide 2, 22 items analyzed by speech therapists working in CI services in the postoperative sector were selected in the second round. Conclusion Based on the analysis of the two rounds, the “Guide for the preparation of speech-language pathology reports: intersection between CI service and rehabilitators” was developed. This material can be applied in the follow-up of implanted children, standardizing the information shared about the electronic device, evaluation results, monitoring of results and therapeutic process of this population.

RESUMO Objetivo Desenvolver guia para elaboração de relatórios fonoaudiológicos de crianças implantadas para serem compartilhados entre fonoaudiólogos dos serviços de implante coclear (IC) e reabilitadores. Método O método Delphi foi utilizado para selecionar os itens relevantes e fundamentais que deveriam constar nas duas versões propostas para compor o guia: Guia 1 - Relatórios fonoaudiológicos fornecidos pelo serviço de IC aos reabilitadores, e Guia 2 - Relatórios fonoaudiológicos fornecidos pelos reabilitadores aos serviços de IC. Vinte e um fonoaudiólogos especialistas e com experiência na área de implante coclear e de reabilitação auditiva participaram da discussão e do julgamento dos itens durante as rodadas de seleção. Considerou-se consenso quando o item obteve a concordância igual ou superior a 80% entre os participantes, sendo selecionados para comporem os dois guias. Resultados Após as duas rodadas, 21 itens do Guia 1 obtiveram consenso entre os terapeutas, ou seja, mais de 80% deles concordaram que estes itens deveriam estar presentes no relatório enviado pelo serviço de IC. Para o Guia 2, 22 itens analisados pelos fonoaudiólogos atuantes em serviços de IC setor pós-operatório, foram selecionados na segunda rodada. Conclusão A partir da análise das duas rodadas, foi desenvolvido o “Guia para a elaboração de relatórios fonoaudiológicos: intersecção entre serviço de IC e reabilitadores”. Este material pode ser aplicado na rotina de acompanhamento de crianças implantadas, padronizando as informações compartilhadas sobre o dispositivo eletrônico, resultados de avaliações, monitoramento dos resultados e processo terapêutico dessa população.

https://doi.org/10.1590/2317-1782/20232022177pt

Study of the upper pole after subtotal splenectomy in rats
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Martins, Amanda Lessa

; Parreira, Anna Bárbara Scárdua

; Grossi, Maria Luiza Font Juliá

; Benevides, Raquel de Azevedo

; Motta, Luciene Lage da

; Pimassoni, Lucia Helena Sagrillo

; Borjaili, Andrea Saade Daher

; Paulo, Marcela Souza Lima

; Paulo, Danilo Nagib Salomão

Acta Cirúrgica Brasileira

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2022, Volume 37 N. 11 elocation e371103

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: To evaluate macro/microscopic viability of the upper pole (UP) in rats after 80 days of subtotal splenectomy preserving the upper pole (SSPUP). Methods: Twenty-five male Wistar rats were submitted to SSPUP. After 80 days, the rats were euthanized, and the remaining UP was evaluated macroscopically regarding appearance, color, consistency, length, width, thickness, and presence of fibrosis/necrosis; and microscopically regarding presence of red and white pulp, fibrosis/necrosis. Results: Two rats died during surgery and were removed from the statistical analysis. There was statistically significant increase in length and width between the pre and postoperative in the experimental group, with no significant difference in thickness. In the manipulation group, the macroscopic appearance of the spleen was normal in pre and postoperative, with viability preserved. In the experimental group, two UP of the spleen were not found during the second surgery. Macroscopically, it was observed absence of fibrosis and necrosis in all cases. Microscopically, the white and red pulp were intact in both groups. Two spleens of rats in the manipulation group presented areas with fibrosis and necrosis focus, which were not enough to be considered inviable. Conclusions: The UP of the spleen remained viable in 91.3% of the cases.

https://doi.org/10.1590/acb371103

Independência funcional e espirometria em pacientes adultos pós-unidade de terapia intensiva
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Abentroth, Lilian Regina Lengler

; Osaku, Erica Fernanda

; Silva, Mayara Manzoni Marques da

; Jaskowiak, Jaiane Luiza

; Zaponi, Renata de Souza

; Ogasawara, Suely Mariko

; Leite, Marcela Aparecida

; Costa, Cláudia Rejane Lima de Macedo

; Porto, Itamar Regazzo Pedreschi

; Jorge, Amaury Cezar

; Duarte, Péricles Almeida Delfino

Revista Brasileira de Terapia Intensiva

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apr 2021, Volume 33 N. 2 Pages 243 - 250

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Relatar a independência funcional e o grau de comprometimento pulmonar em pacientes adultos 3 meses após a alta da unidade de terapia intensiva. Métodos: Este foi um estudo de coorte retrospectiva conduzido em uma unidade de terapia intensiva multiprofissional para pacientes adultos em um único centro. Incluíram-se pacientes admitidos à unidade de terapia intensiva entre janeiro de 2012 e dezembro de 2013 que, 3 meses mais tarde, foram submetidos à espirometria e responderam ao questionário Medida de Independência Funcional. Resultados: Os pacientes foram divididos em grupos segundo sua classificação de independência funcional e espirometria. O estudo incluiu 197 pacientes, que foram divididos entre os grupos maior dependência (n = 4), menor dependência (n = 12) e independente (n = 181). Na comparação dos três grupos com relação à classificação pela Medida de Independência Funcional, pacientes com maior dependência tinham escores Acute Physiology and Chronic Health Evaluation II e Sequential Organ Failure Assessment mais altos quando da admissão à unidade de terapia intensiva, idade mais avançada, mais dias sob ventilação mecânica e tempo mais longo de permanência na unidade de terapia intensiva e no hospital. A maioria dos pacientes apresentava comprometimento pulmonar, sendo o padrão obstrutivo o mais frequentemente observado. Na comparação da independência funcional com a função pulmonar, observou-se que, quanto pior a condição funcional, pior a função pulmonar, observando-se diferenças significantes em relação ao pico de fluxo expiratório (p = 0,030). Conclusão: Em sua maioria, os pacientes que retornaram ao ambulatório 3 meses após a alta tinham boa condição funcional, porém apresentavam comprometimento pulmonar relacionado com o grau de dependência funcional.

ABSTRACT Objective: To relate functional independence to the degree of pulmonary impairment in adult patients 3 months after discharge from the intensive care unit. Methods: This was a retrospective cohort study conducted in one adult intensive care unit and a multi-professional post-intensive care unit outpatient clinic of a single center. Patients admitted to the intensive care unit from January 2012 to December 2013 who underwent (3 months later) spirometry and answered the Functional Independence Measure Questionnaire were included. Results: Patients were divided into groups according to the classification of functional independence and spirometry. The study included 197 patients who were divided into greater dependence (n = 4), lower dependence (n = 12) and independent (n = 181) groups. Comparing the three groups, regarding the classification of the Functional Independence Measure, patients with greater dependence had higher Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment values at intensive care unit admission with more advanced age, more days on mechanical ventilation, and longer stay in the intensive care unit and hospital. The majority of patients presented with pulmonary impairment, which was the obstructive pattern observed most frequently. When comparing functional independence with pulmonary function, it was observed that the lower the functional status, the worse the pulmonary function, with a significant difference being observed in peak expiratory flow (p = 0.030). Conclusion: The majority of patients who returned to the outpatient clinic 3 months after discharge had good functional status but did present with pulmonary impairment, which is related to the degree of functional dependence.

https://doi.org/10.5935/0103-507x.20210031 208 downloads

Acute effects of ropivacaine hydrochloride on corneal endothelial cell ultrastructure of horses: ex vivo study
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Muccillo, Marcele de Souza

; Silva, Alessandra Fernandez da

; Seibel, Maiara Poersch

; Baptista, Renata Lima

; Torikachvili, Marcela

; Petersen, Michelle Becker

; Pigatto, João Antonio Tadeu

Ciência Rural

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2021, Volume 51 N. 10 elocation e20200763

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Objetivou-se avaliar os efeitos agudos do cloridrato de ropivacaína no endotélio da córnea de equinos. Quarenta e oito olhos de equinos foram divididos aleatoriamente em três grupos. No grupo A o endotélio da córnea foi exposto a cloridrato de ropivacaína a 0,75% por 60 segundos. No grupo B o endotélio da córnea foi exposto a cloridrato de ropivacaína a 0,75% por 15 minutos. No grupo C o endotélio da córnea foi exposto à solução salina balanceada por 60 segundos. As amostras foram preparadas para avaliação com microscopia eletrônica de varredura. Eletromicrografias eletrônicas de varredura foram obtidas aleatoriamente de cada amostra. As imagens foram analisadas e, com o auxílio de um programa para morfometria foram medidas as áreas sem células endoteliais. A perda endotelial média foi expressa em porcentagem em relação à área total das amostras do grupo A foi de 5,28%. A perda endotelial média de amostras do grupo B foi expressa em porcentagem em relação à área total, foi de 20,39%. O dano ao endotélio da córnea foi significativamente maior no grupo B, comparado aos grupos A e C. O cloridrato de ropivacaína a 0,75% induziu dano agudo nas células do endotélio da córnea de equinos.

ABSTRACT: The objective of this study was to evaluate the acute effects of ropivacaine hydrochloride on the corneal endothelium of horses. Forty-eight eyes were obtained from a commercial slaughterhouse and were randomly divided into three groups. In group A, the corneal endothelium was exposed to 0.75% ropivacaine hydrochloride for 60 seconds. In group B, the corneal endothelium was exposed to 0.75% ropivacaine hydrochloride for 15 minutes. In group C, the corneal endothelium was exposed to a balanced saline solution for 60 seconds. Afterwards, all samples were prepared for evaluation with scanning electron microscopy. Random electromicrographs were obtained from each sample. The images were analysed and, with the aid of software, areas with no endothelial cells were measured. The average endothelial loss, expressed as a percentage in relation to the total area, of the samples in group A was 5.28%. The average endothelial loss of samples from group B, expressed as a percentage in relation to the total area, was 20.39%. The damage to the corneal endothelium was significantly greater in group B compared to groups A and C. It was possible to conclude that 0.75% ropivacaine hydrochloride induced acute damage to corneal endothelium cells.

https://doi.org/10.1590/0103-8478cr20200763 113 downloads

Treatment of agrammatism in oral and written production in patients with Broca’s aphasia The use of implicit and explicit learning
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Silagi, Marcela Lima

; Ferreira, Olavo Panseri

; Almeida, Isabel Junqueira de

; Simões, Janaina de Souza

; Zampieri, Sueli Aparecida

; Santana, Beatriz Raz Franco de

; Mansur, Letícia Lessa

Dementia & Neuropsychologia

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jun 2020, Volume 14 N. 2 Pages 103 - 109

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo. Várias abordagens terapêuticas para a reabilitação do agramatismo utilizam métodos implícitos e explícitos de aprendizado. Objetivo: Verificar o efeito dos métodos adaptados Mapping Therapy e ORLA (aprendizagem explícita versus implícita) na produção oral e escrita de discurso em pacientes agramáticos com afasia de Broca. Métodos: Seis indivíduos foram submetidos aos tratamentos Mapping Therapy e ORLA. Amostras das produções oral e escrita na tarefa de descrição da prancha foram comparadas antes e após o tratamento. Resultados: No método Mapping Therapy, os pacientes apresentaram melhor desempenho após o tratamento nas seguintes variáveis relacionadas à produção escrita: número de palavras, substantivos, verbos, palavras de classe fechada e número de frases completas. Em relação à emissão oral, os pacientes mantiveram desempenho semelhante pré e pós processo terapêutico. No método ORLA, os pacientes apresentaram diferença significativa antes e após o processo terapêutico nas variáveis relacionadas à produção oral, com aumento no número de palavras, número de verbos e velocidade de fala. Não houve diferença no desempenho pré e pós tratamento na produção escrita. Conclusão: Tanto a aprendizagem implícita como a explícita têm o potencial de serem usadas no tratamento do agramatismo. A Mapping Therapy foi mais eficaz no tratamento do agramatismo na produção escrita, enquanto o ORLA foi mais eficaz para o agramatismo na produção oral.

Abstract. Several approaches to the rehabilitation of agrammatism use implicit and explicit learning methods. Objective: To verify the effect of adapted Mapping Therapy and ORLA methods (explicit versus implicit learning) on the oral and written production in spontaneous language among agrammatic patients with Broca’s aphasia. Methods: Six individuals were submitted to Mapping Therapy and ORLA (Oral Reading for Language in Aphasia) treatments. Samples of oral and written production from a picture description task were compared pre and post-treatment. Results: In Mapping Therapy, the patients presented better performance after the training for the variables related to written production: number of words, nouns, verbs, closed-class words, and number of complete sentences. Regarding oral output, the patients had similar performance before and after the therapeutic process. In ORLA, the patients presented a significant difference before and after the therapeutic process in the variables related to oral production, increasing the number of words, number of verbs, and speech rate. There was no difference in pre and post-treatment performance in written production. Conclusion: Both implicit and explicit learning can be used in the treatment of agrammatism. Mapping Therapy was more effective for the treatment of agrammatism in written production, while ORLA was more effective for the agrammatism in oral production.

https://doi.org/10.1590/1980-57642020dn14-020002 2095 downloads

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy
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Paulo, Lucas Nagib Lemos

; Alexander, Daniel Robert

; Vallandro, Elisa Ines Demuner

; Benevides, Raquel de Azevedo

; Motta, Luciene Lage da

; Paulo, Marcela Souza Lima

; Paulo, Danilo Nagib Salomão

Acta Cirúrgica Brasileira

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2020, Volume 35 N. 9 elocation e202000902

Abstract: En | Text: En | PDF: En

Abstract Purpose To evaluate the viability of the upper (UP) and lower pole (LP) of the spleen from a macro and microscopic point of view, after subtotal splenectomy with preservation (SSP) of the UP and the LP. Methods Seventeen male Wistar rats, two months old, were submitted to SSPUP and SSPLP and 5 to simulated operation (SG). After 80 days, the rats were euthanized, and the remaining LP and UP and intact spleens were evaluated macroscopically and microscopically. Results Two rats died during the operation. Macroscopic analysis showed that in 15 LP, one of them was not viable and in 15 UP and in 5 spleens in the SG, all were viable. In the statistical analysis, there was no difference in relation to viability. The LP and UP analyzed showed variation. As for the length, the UP increased significantly; however, in relation to the width, there was a significant increase in the LP in relation to the UP. In addition, the weight of the UP was significantly greater than that of the LP. Microscopic analysis attested viability of the splenic remnants. Conclusion There was no significant difference regarding the viability of UP and LP, in macroscopy and microscopy.

https://doi.org/10.1590/s0102-865020200090000002 392 downloads

The influence of splenic tissue on the survival and TCD4 and TCD8 lymphocyte rates in rats subjected to fecal peritonitis induction
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Borjaili, Andréa Saade Daher

; Nunes, Giseli Celestino

; Silveira, Julia Belizário

; Dall'Orto, Flávia Heiderich

; Lorenzoni, Gabriel Souza

; Borjaili, Matheus Eduardo Daher

; Campagnaro, Bianca Prandi

; Lima, Maressa Cristiane Malini de

; Paulo, Marcela Souza Lima

; Paulo, Danilo Nagib Salomão

; Nunes, Tarcizo Afonso

Acta Cirúrgica Brasileira

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2020, Volume 35 N. 10 elocation e202001003

Abstract: En | Text: En | PDF: En

Abstract Purpose: Comparing survival rates of rats subjected to spleen procedures after fecal peritonitis induction. Assessing changes in TCD4 and CD8 lymphocyte rates before and after the procedures. Correlating animal survival with CD4 and CD8 lymphocytes. Methods: Thirty male Wistar rats were distributed into 3 groups of ten: spleen manipulation (SM); total splenectomy (TS); subtotal splenectomy with preservation of the inferior pole (IP). Rats were subjected to surgical procedure depending on the group. Seven days after surgery they underwent induction of peritonitis and survival time was recorded. All animals were subjected to two blood collections: before surgery and 70 days after it for TCD4/TCD8 lymphocyte counting. Results: Mean survival time was longer in the IP and SM groups and shorter in the TS group; there was significant difference between them. The comparison of the median number of CD4 did not present changes, whereas the comparison of the median number of CD8 decreased in the SM and IP groups. The correlation between the median number of TCD4 and TCD8 lymphocytes and the animals’ survival was not significant. Conclusion: The maintenance of splenic tissue contributed to increase the survival of rats and there was a change in the number of TCD8 lymphocytes.

https://doi.org/10.1590/s0102-865020200100000003 448 downloads

COMPLICAÇÕES PUERPERAIS EM UM MODELO MEDICALIZADO DE ASSISTÊNCIA AO PARTO
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Monteschio, Lorenna Viccentine Coutinho

; Marcon, Sonia Silva

; Santos, Rubia Mariana de Souza

; Vieira, Viviane Cazetta de Lima

; Oliveira, Marcela Demitto de

; Goes, Herbert Leopoldo de Freitas

; Oliveira, Rosana Rosseto

; Mathias, Thais Aidar de Freitas

Reme: Revista Mineira de Enfermagem

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2020, Volume 24 elocation e1319

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objective: to analyze the puerperal complications in women assisted for childbirth by the public health sector. Method: this is a cross-sectional study with 358 women in the postpartum period who had their childbirth financed by the Unified Health System in a city in southern Brazil. The following procedure was carried out for data collection: an interview with the puerperal woman on hospital admission - at least 12 hours after delivery; consultation of the maternal record to obtain information regarding sociodemographic characteristics, interventions and complications; and telephone contact with the puerperal woman 40 days after delivery to assess possible late complications. Complications were analyzed according to sociodemographic and obstetric data, newborn data, and obstetric intervention performed during labor or delivery. The association analysis was assessed using the chi-square calculation, with a significance level of p≤0.05. Results: among the women in the postpartum period, 31.3% had at least one puerperal complication and the need for antimicrobials was the most frequent (12.8%) and placental complications the least frequent (2.5%). Cesarean section was associated with the use of antimicrobials (OR = 2.2; p = 0.0211) and readmission (OR = 9.9; p = 0.007). The greater the number of interventions performed, there was a progressive increase in puerperal complications, which indicates that the studied hospitals still adopt the medicalized model of childbirth care, with high rates of obstetric interventions. Conclusion: the high rate of puerperal complications was associated with the medicalized obstetric model, which can be evidenced by the complications independent of the type of delivery.

RESUMEN Objetivo: analizar las complicaciones puerperales en mujeres atendidas en salud pública para el parto. Método: estudio transversal con 358 puérperas cuyo parto fue financiado por el Sistema Único de Salud en una ciudad del sur de Brasil. Para la recogida datos se llevaron a cabo los siguientes procedimientos: entrevista con la puérpera internada en el hospital, al menos 12 horas después del parto; consulta del registro materno para obtener información sobre las características sociodemográficas, intervenciones y complicaciones; y contacto telefónico con la puérpera 40 días después del parto para evaluar posibles complicaciones tardías. Las complicaciones se analizaron de acuerdo con los datos sociodemográficos, obstétricos, del recién nacido y de la intervención obstétrica realizada durante el trabajo de parto o el parto. El análisis de asociación se evaluó mediante el cálculo de chi-cuadrado, con un nivel de significación de p≤0.05. Resultados: el 31.3% de las mujeres tuvo al menos una complicación puerperal y necesidad de antimicrobianos como más frecuente (12.8%) y complicaciones placentarias como menos frecuente (2.5%). La cesárea se asoció con el uso de antimicrobianos (OR = 2.2; p = 0.0211) y reingreso (OR = 9.9; p = 0.007). Se observó el aumento progresivo de las complicaciones puerperales cuanto mayor era el número de intervenciones realizadas, lo cual indica que los hospitales estudiados aún adoptan el modelo medicalizado de atención al parto, con mayores tasas de intervenciones obstétricas. Conclusión: la alta tasa de complicaciones puerperales se asoció con el modelo obstétrico medicalizado, lo cual se puede constatar por la aparición de complicaciones, independientemente del tipo de parto.

RESUMO Objetivo: analisar as complicações puerperais em mulheres atendidas para o parto pelo setor público de saúde. Método: estudo transversal com 358 puérperas que tiveram parto financiado pelo Sistema Único de Saúde em município do Sul do Brasil. Para a coleta de dados foram realizadas: entrevista com a puérpera na internação hospitalar - pelo menos 12 horas após o parto; consulta ao prontuário materno para levantar informações referentes às características sociodemográficas, intervenções e complicações; e contato telefônico com a puérpera 40 dias após o parto para levantamento de possíveis complicações tardias. As complicações foram analisadas segundo dados sociodemográficos, obstétricos, dados do recém-nascido e intervenção obstétrica realizada durante o trabalho de parto ou parto. A análise de associação foi avaliada por meio do cálculo do qui-quadrado, com nível de significância p≤0,05. Resultados: das puérperas, 31,3% tiveram pelo menos uma complicação puerperal cuja necessidade de antimicrobianos foi a mais frequente (12,8%) e as complicações placentárias as menos frequente (2,5%). A cesariana esteve associada à utilização de antimicrobianos (OR=2,2; p=0,0211) e à reinternação (OR=9,9; p=0,007). Foi observado progressivo aumento de complicações puerperais quanto maior o número de intervenções realizadas, o que indica que os hospitais estudados ainda adotam o modelo medicalizado de assistência ao parto, com elevados índices de intervenções obstétricas. Conclusão: a alta taxa de complicações puerperais esteve associada ao modelo obstétrico medicalizado, o que pode ser evidenciado pela ocorrência de complicações independentes do tipo de parto.

https://doi.org/10.5935/1415-2762.20200056 377 downloads

Maximum inspiratory and expiratory pressures in the pre and postoperative periods of patients with incisional abdominal hernia corrected by Lázaro da Silva technique
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PAULO, DANILO NAGIB SALOMÃO

; DA-SILVA, ALCINO LÁZARO

; PAULO, LUCAS NAGIB LEMOS

; CALIMAN, ALEXANDRE OLIOSI

; PAULO, MARCELA SOUZA LIMA

; LEMOS-PAULO, MATHEUS NAGIB

Revista do Colégio Brasileiro de Cirurgiões

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2020, Volume 47 elocation e20202430

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: verificar o efeito da herniorrafia incisional abdominal longitudinal na pressão dos músculos da respiração. Método: a técnica de herniorrafia incisional utilizada foi a proposta por Lázaro da Silva. Para aferir a pressão foi utilizado manômetro de água, em 20 pacientes, idade mediana 48,5 anos (mínimo 24, máximo 70). Foram analisadas a pressão máxima inspiratória no nível do volume residual (PIVR) e da capacidade residual funcional (PICRF) e a pressão máxima expiratória da capacidade residual funcional (PECRF) e da capacidade pulmonar total (PECPT), no pré-operatório e pós-operatório tardio (entre 40 e 90 dias), em 13 pacientes com hérnias incisionais grandes e em 7 pacientes com hérnias incisionais médias. Resultados: houve aumento significante da PICRF (p=0.027), da PIVR (p=0.011), da PECPT (p=0.003) nos pacientes com hérnias incisionais grandes. A PECRF aumentou, porém de forma não significante. Nos pacientes com hérnias incisionais médias as alterações não foram significantes. Conclusão: a correção cirúrgica da hérnia incisional grande melhora a função dos músculos da respiração, porém a cirurgia da hérnia incisional média não altera a referida função.

ABSTRACT Objective: To verify the effect of longitudinal abdominal incisional herniorrhaphy on respiratory muscle pressure. Method: The technique of incisional herniorrhaphy used was proposed by Lázaro da Silva. To measure the pressure, we used a water manometer in 20 patients, median age 48.5 years (range 24 70). We analyzed the maximum inspiratory pressure at the level of residual volume (IP-RV) and functional residual capacity (IP-FRC) and the maximum expiratory pressure of functional residual capacity (EP-FRC) and total lung capacity (EP-TLC) in the preoperative and late postoperative (40 90 days) periods, in 13 patients with large incisional hernias and in 7 patients with medium incisional hernias. Results: There was a significant increase in IP-FRC (p = 0.027), IP-RV (p = 0.011) and EP-TLC (p = 0.003) in patients with large incisional hernias. EP-FRC increased, but not significantly. In patients with medium incisional hernias, the changes were not significant. Conclusion: Surgical correction of large incisional hernias improves the function of the breathing muscles; however, surgery for medium incisional hernias does not alter this function.

https://doi.org/10.1590/0100-6991e-20202430 1072 downloads

10.

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

; Castanheira, Elen Rose Lodeiro

; Alves, Ana Maroso

; Adania, Carolina Simone Souza

; Loch, Ana Paula

; Monroe, Aline Aparecida

; Souza, Rosa Alencar

; Gianna, Maria Clara

; Caminada, Sirlene

; Farias, Norma Suely de Oliveira

; Sousa, Paula de Oliveira e

; Domingues, Carmen Silva Bruniera

; Silva, Mariliza Henrique da

; Cervantes, Vilma

; Yamashiro, Juliana

; Caraciolo, Joselita Maria de Magalhães

; Silva, Fabiano Lima da

; Nemes Filho, Alexandre

; Jesus, Gabriel Lima de

; Helena, Ernani Tiaraju de Santa

; Albiero, José Francisco Gontan

; Lima, Marcela Soares Silveira

; Bellenzani, Renata

; Kehrig, Ruth Terezinha

; Vale, Felipe Campos do

; Nunes, Luceime Olivia

; Mendonça, Carolina Siqueira

; Zarili, Thais Fernanda Tortorelli

; Vilela, Mara Cristina

; Dantas, Jean Carlos de Oliveira

; Paula, Ivone de

; Tayra, Ângela

; Coelho, Débora Moraes

; Santos, Glauber Palha dos

; Quevedo, Dulce Castro

; Silva, Marcia Aparecida da

; Silva, Iraci Batista da

; Nasser, Mariana Arantes

; Andrade, Marta Campagnoni

; Santos, Maria Altenfelder

; Mercuri, Juliana

; Trindade, Katia Valeska

; Neves, Maria Aparecida Teixeira das

; Toledo, Renata Villanueva Alves de

; Almeida, Maria Cecília Rossi de

; Lima, Iraty Nunes

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Modelos de cuidado contínuo baseiam recentes estratégias em HIV, infecções sexualmente transmissíveis e hepatite C (HCV). Métodos: Desenvolveram-se modelos de contínuo do cuidado em HIV, HCV e sífilis congênita incluindo todas as etapas da atenção, desde a promoção e a prevenção até o controle clínico/cura. O modelo baseou a intervenção QualiRede, desenvolvida em parceria entre universidade e Sistema Único de Saúde (SUS), direcionada a gestores e demais profissionais de 6 regiões de saúde prioritárias em São Paulo e Santa Catarina. Selecionaram-se indicadores para cada etapa do contínuo do cuidado, provenientes dos sistemas de informação do SUS e dos questionários de avaliação de processo Qualiaids e QualiAB. Os indicadores formaram a base técnica de duas oficinas com profissionais e gestores de cada região: a primeira para identificar problemas e formar um Grupo Técnico Regional; e a segunda para construir planos de ação e metas a fim de melhorar o desempenho regional. Resultados: Os indicadores estão disponíveis no website www.qualirede.org. As oficinas ocorreram em quatro regiões de São Paulo (Alto Tietê, Baixada Santista, Grande ABC e Registro) e uma região de Santa Catarina (Foz do Rio Itajaí), resultando em planos regionais em São Paulo, mas não em Santa Catarina. Observou-se domínio limitado dos novos protocolos para HIV e HCV e uso incipiente de indicadores na rotina dos serviços. Conclusão: Melhorar o desempenho do contínuo do cuidado exige apropriação dos indicadores de desempenho e coordenação integrada dos fluxos de atenção em todos os níveis de gestão.

ABSTRACT Introduction: Care continuum models have supported recent strategies against sexually transmitted diseases, such as HIV and Hepatitis C (HCV). Methods: HIV, HCV, and congenital syphilis care continuum models were developed, including all stages of care, from promotion/prevention to clinical control/cure. The models supported the intervention QualiRede, developed by a University-Brazilian National Health System (SUS) partnership focused on managers and other professionals from six priority health regions in São Paulo and Santa Catarina. Indicators were selected for each stage of the care continuum from the SUS information systems and from the Qualiaids and QualiAB facility’s process evaluation questionnaires. The indicators acted as the technical basis of two workshops with professionals and managers in each region: the first one to identify problems and to create a Regional Technical Group; and the second one to design action plans for improving regional performance. Results: The indicators are available at www.qualirede.org. The workshops took place in the regions of Alto Tietê, Baixada Santista, Grande ABC, and Registro (São Paulo) and of Foz do Rio Itajaí (Santa Catarina), which resulted in regional action plans in São Paulo, but not in Santa Catarina. A lack of awareness was observed regarding the new HIV and HCV protocols, as well as an incipient use of indicators in routine practices. Conclusion: Improving the performance of the care continuum requires appropriation of performance indicators and coordination of care flows at local, regional, and state levels of management.

https://doi.org/10.1590/1980-549720190010.supl.1

11.

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

; Castanheira, Elen Rose Lodeiro

; Alves, Ana Maroso

; Adania, Carolina Simone Souza

; Loch, Ana Paula

; Monroe, Aline Aparecida

; Souza, Rosa Alencar

; Gianna, Maria Clara

; Caminada, Sirlene

; Farias, Norma Suely de Oliveira

; Sousa, Paula de Oliveira e

; Domingues, Carmen Silva Bruniera

; Silva, Mariliza Henrique da

; Cervantes, Vilma

; Yamashiro, Juliana

; Caraciolo, Joselita Maria de Magalhães

; Silva, Fabiano Lima da

; Nemes Filho, Alexandre

; Jesus, Gabriel Lima de

; Helena, Ernani Tiaraju de Santa

; Albiero, José Francisco Gontan

; Lima, Marcela Soares Silveira

; Bellenzani, Renata

; Kehrig, Ruth Terezinha

; Vale, Felipe Campos do

; Nunes, Luceime Olivia

; Mendonça, Carolina Siqueira

; Zarili, Thais Fernanda Tortorelli

; Vilela, Mara Cristina

; Dantas, Jean Carlos de Oliveira

; Paula, Ivone de

; Tayra, Ângela

; Coelho, Débora Moraes

; Santos, Glauber Palha dos

; Quevedo, Dulce Castro

; Silva, Marcia Aparecida da

; Silva, Iraci Batista da

; Nasser, Mariana Arantes

; Andrade, Marta Campagnoni

; Santos, Maria Altenfelder

; Mercuri, Juliana

; Trindade, Katia Valeska

; Neves, Maria Aparecida Teixeira das

; Toledo, Renata Villanueva Alves de

; Almeida, Maria Cecília Rossi de

; Lima, Iraty Nunes

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720190010.supl.1 2475 downloads

12.

Effects of 1,25-dihydroxycholecalciferol and reduced vitamin D3 level on broiler performance and bone quality
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Castro, Fernanda Lima de Souza

; Baião, Nelson Carneiro

; Ecco, Roselene

; Louzada, Mário Jefferson Quirino

; Melo, Érica de Faria

; Saldanha, Mariana Masseo

; Triginelli, Marcela Viana

; Lara, Leonardo José Camargos

Revista Brasileira de Zootecnia

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2018, Volume 47 elocation e20170186

Abstract: En | Text: En | PDF: En

ABSTRACT This study was conducted to evaluate the effect of two levels of vitamin D3 with or without 1,25- dihydroxycholecalciferol (1,25(OH)2D3) on live performance and bone quality of broiler chickens. For that, we used a completely randomized design in a 2 × 2 factorial arrangement, with eight replicates of 30 Cobb®500 male broiler chicks each (n = 960). The two levels of vitamin D3 and the addition or not of 0.5 μg 1,25(OH)2D3/kg were considered as main factors. The vitamin D3 levels were: 2500/2000 IU/kg and 1250/1000 IU/kg for the starter (1 to 21 days) and grower (22 to 40 days) phases, respectively, with the first representing the levels used in industry (100%) and the second, a reduction in 50% of those levels. The 1,25(OH)2D3 source was Solanum glaucophyllum. On days 21 and 40, one broiler per replicate was killed and long bones were removed for analyses of mineral percentage, bone mineral density, biomechanical properties, and morphology. No significant differences were found related to vitamin D3 levels and the addition or not of 1,25(OH)2D3 for live performance, mineral percentage, strength, stiffness, and morphology. Toughness was lower when 1,25(OH)2D3 was used at 21 days, but this effect was not observed at 40 days of age. Bone mineral density was greater when 100% of vitamin D3 was used at 40 days of age. The reduction of up to 50% of vitamin D3 levels is sufficient to ensure performance and bone development of broilers at 21 and 40 days of age. The inclusion of 0.5 μg 1,25(OH)2D3/kg in addition to diets with sufficient levels of vitamin D3 shows no effect on the improvement of those parameters at the same ages.

https://doi.org/10.1590/rbz4720170186 1779 downloads

13.

Occurrence of anti-Toxoplasma gondii antibodies and parasite DNA in backyard chicken breeding in Northeast, Brazil
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Fernandes, Marcela Fernanda Torres Samico

; Cavalcanti, Erika Fernanda Torres Samico Fernandes

; Silva, José Givanildo da

; Mota, André da Rocha

; Souza Neto, Orestes Luiz de

; Santos, André de Souza

; Albuquerque, Pedro Paulo Feitosa de

; Lima, Débora Costa Viegas de

; Mota, Rinaldo Aparecido

Revista Brasileira de Parasitologia Veterinária

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mar 2016, Volume 25 N. 1 Pages 105 - 108

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo do presente estudo foi investigar a ocorrência de anticorpos anti-Toxoplasma gondii e de DNA do parasito em galinhas de criações domésticas, na região metropolitana de Recife, Brasil. No total, 212 amostras de soro foram coletadas de aves de 16 estabelecimentos e de 12 galinhas de criações domésticas nos seis distritos sanitários de Recife. Para a pesquisa de anticorpos anti-Toxoplasma gondii foi utilizada a Reação de Imunofluorescência Indireta (RIFI). A Reação em Cadeia da Polimerase (PCR) foi utilizada para detectar o DNA de T. gondii em fragmentos de cérebro, coração, fígado e pulmão. Das amostras analisadas por sorologia, 86/212 (40,56%) foram positivas. Das amostras analisadas por PCR, 2/212 (16,7%) foram positivas, em ambos os testes (sorológicos e moleculares). A presença de anticorpos anti-T. gondii e de DNA parasitário nos tecidos desses animais são aspectos preocupantes para saúde pública, porque há o risco de transmissão do parasita para humanos através da ingestão de carne mal cozida ou crua. Com base nos resultados obtidos, a adoção de medidas preventivas que evitem o acesso de gatos às criações de galinhas deve ser incentivada, uma vez que esses animais foram identificados na maioria das propriedades estudadas.

Abstract The aim of the present study was to investigate the occurrence of anti-Toxoplasma gondii antibodies and parasite DNA in backyard chickens bred in the metropolitan area of Recife, Brazil. In total, 212 serum samples were collected from 16 properties, and 12 backyard chickens were collected in the six sanitary districts of Recife. An indirect immunofluorescence assay (IFA) was used to investigate the occurrence of anti-Toxoplasma gondii antibodies. Polymerase chain reaction (PCR) was used to detect T. gondii DNA in brain, heart, liver and lung specimens. Of the samples analyzed by serology, 86/212 (40.56%) were positive; of the samples analyzed by PCR, 2/12 (16.7%) were positive, with both samples positive by both tests (serological and molecular). The presence of antibody anti-T. gondii and parasite DNA in tissues of these animals are worrying aspects for public health because there is a risk of transmission of the parasite to humans through eating undercooked or raw meat. Based on the results, the adoption of preventive measures to prevent the cats access to the chickens creations should be encouraged, since these animals were identified in most of the studied properties.

https://doi.org/10.1590/S1984-29612016012 1507 downloads

14.

Effect of total splenectomy in the lipid profile in mice
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Demuner, Bianca Lacerda

; Pinho, Gotardo Zini

; Thomaz, João Cunha

; Stegmiller, Nataly Pescinalli

; Mendes, Roberta Miranda de Araújo

; Paulo, Marcela Souza Lima

; Paulo, Danilo Nagib Salomão

Acta Cirúrgica Brasileira

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may 2015, Volume 30 N. 5 Pages 306 - 312

Abstract: En | Text: En | PDF: En

PURPOSE: To analyze total splenectomy effect on the lipid profile - total cholesterol, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), very-low-density lipoprotein cholesterol (VLDL) and triglycerides levels, in Balb/c mice.METHODS: Thirty Balb/c male mice, one (1) month old and average weight 26.2g ± 4.0 were used in the experiment. They were distributed into three groups of 10 animals each: a control group (non-operated), a simulation group (spleen manipulation) and the splenectomy group. The animals were subjected to blood sampling to measure plasma lipid levels, at three different times: before surgery, days 30 and 75 of the experiment.RESULTS: Increased total cholesterol and LDL were observed in the control group from the start to end of the experiment. The simulation group showed increased rates of VLDL and triglycerides at the 30th and 75th days. Splenectomized animals showed no significant change.CONCLUSION: Total splenectomy did not induce increased plasma lipids levels of in Balb/c mice.

https://doi.org/10.1590/S0102-865020150050000001 2005 downloads

15.

Micronucleus test in peripheral blood of rats treated with hyperbaric oxygen after subtotal splenectomy preserving the lower pole
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Paulo, Marcela Souza Lima

; Souza, Ingryd Fortes

; Wandekoken, Kethleen Gomes

; Silva, Karina Balestreiro

; Dutra, Jean Carlos Vencioneck

; Freitas, Josivany Valério de

; Stegmiller, Nataly Pescinalli

; Pimassoni, Lúcia Helena Sagrillo

; Batitucci, Maria do Carmo Pimentel

; Paulo, Danilo Nagib Salomão

; Errera, Flávia Imbroisi Valle

Acta Cirúrgica Brasileira

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apr 2015, Volume 30 N. 4 Pages 264 - 269

Abstract: En | Text: En | PDF: En

PURPOSE: To assess the mutagenic potential of the oxygen inhalation therapy (HBO), by means of the micronucleus test, performed in peripheral blood of rats that underwent subtotal splenectomy with lower pole preservation (ESTPI), after HBO sessions or simulations.METHODS: Eighteen male Wistar rats, were distributed into three groups of six animals: group 1 - submitted to ESTPI and HBO sessions; group 2 - submitted to ESTPI and HBO simulations; group 3 - underwent cyclophosphamide administration. In groups 1 and 2, blood samples from the animals' tails were collected before surgery (T0) and immediately after the 13th HBO session or simulation (T1). In group 3, tail blood samples were collected from animals before (T0) and 24 hours after (T1) cyclophosphamide (CP) delivery. The number of micronucleated normochromatic erythrocytes (MNNCE) was determined by blind counting 2000 normochromatic erythrocytes (NCE) per animal.RESULTS:Micronuclei average after CP delivery in group 3 was higher than before its use, thus confirming the mutagenic activity of this drug (p=0.01). In groups 1 and 2, no significant difference in the average of Micronuclei was observed when comparing it to blood samples before and after the 13th HBO session or simulation.CONCLUSION: The treatment protocol used in this study did not induce Micronucleus formation in animals submitted to ESTPI and HBO treatment or simulation.

https://doi.org/10.1590/S0102-865020150040000005 2034 downloads

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