ABSTRACT OBJECTIVE: To analyze the effects of early determinants on adolescent fat-free mass. METHODS: A cohort study with 579 adolescents evaluated at birth and adolescence in a birth cohort in São Luís, Maranhão. In the proposed model, estimated by structural equation modeling, socioeconomic status (SES) at birth, maternal age, pregestational body mass index (BMI), gestational smoking, gestational weight gain, type of delivery, gestational age, sex of the newborn, length and weight at birth, adolescent socioeconomic status, “neither study/nor work” generation, adolescent physical activity level and alcohol consumption were tested as early determinants of adolescent fat-free mass (FFM). RESULTS: A higher pregestational BMI resulted in higher FFM in adolescence (Standardized Coefficient, SC = 0.152; p < 0.001). Being female implied a lower FFM in adolescence (SC = −0.633; p < 0.001). The negative effect of gender on FFM was direct (SC = −0.523; p < 0.001), but there was an indirect negative effect via physical activity level (SC = −0.085; p < 0.001). Women were less active (p < 0.001). An increase of 0.5 kg (1 Standard Deviation, SD) in birth weight led to a gain of 0.25 kg/m2 (0.106 SD) in adolescent FFM index (p = 0.034). Not studying or working had a negative effect on the adolescent's FFM (SC = −0.106; p = 0.015). Elevation of 1 SD in the adolescent's physical activity level represented an increase of 0.5 kg/m2 (0.207 SD) in FFM index (p < 0.001). CONCLUSIONS: The early determinants with the greatest effects on adolescent FFM are gender, adolescent physical activity level, pregestational BMI, birth weight and belonging to the “neither-nor” generation.

ABSTRACT Introduction: Although the 2019 severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2, COVID-19) pandemic poses new challenges to the healthcare system to provide support for thousands of patients, there is special concern about common medical emergencies, such as stroke, that will continue to occur and will require adequate treatment. The allocation of both material and human resources to fight the pandemic cannot overshadow the care for acute stroke, a time-sensitive emergency that with an inefficient treatment will further increase mortality and long-term disability. Objective: This paper summarizes the recommendations from the Scientific Department on Cerebrovascular Diseases of the Brazilian Academy of Neurology, the Brazilian Society of Cerebrovascular Diseases and the Brazilian Society of Neuroradiology for management of acute stroke and urgent neuro-interventional procedures during the COVID-19 pandemic, including proper use of screening tools, personal protective equipment (for patients and health professionals), and patient allocation.

RESUMO Introdução: A pandemia causada pelo novo coronavírus da síndrome respiratória aguda grave 2 (SARS-CoV-2, COVID-19) apresenta novos e importantes desafios à gestão de saúde no Brasil. Além da difícil missão de prestar atendimento aos milhares de pacientes infectados pelo COVID-19, os sistemas de saúde têm que manter a assistência às emergências médicas comuns em períodos sem pandemia, tais como o acidente vascular cerebral (AVC), que continuam ocorrendo e requerem tratamento com presteza e eficiência. A alocação de recursos materiais e humanos para o enfrentamento à pandemia não pode comprometer o atendimento ao AVC agudo, uma emergência cujo tratamento é tempo-dependente e se não realizado implica em importante impacto na mortalidade e incapacitação a longo prazo. Objetivo: Este trabalho resume as recomendações do Departamento Científico de Doenças Cerebrovasculares da Academia Brasileira de Neurologia, da Sociedade Brasileira de Doenças Cerebrovasculares e da Sociedade Brasileira de Neurorradiologia para o tratamento do AVC agudo e para a realização de procedimentos de neurointervenção urgentes durante a pandemia de COVID-19, incluindo o uso adequado de ferramentas de triagem e equipamentos de proteção pessoal (para pacientes e profissionais de saúde), além da alocação apropriada de pacientes.

RESUMO Objetivos: avaliar a evolução dos indicadores clínicos que caracterizam a permeabilidade das vias aéreas em pacientes no pós-operatório de cirurgias toracoabdominais e analisar sua relação com a ocorrência do diagnóstico “desobstrução ineficaz das vias aéreas”. Métodos: pesquisa descritiva, quantitativa, longitudinal realizada com 60 pacientes que foram acompanhados por cinco dias consecutivos. Foram utilizados 11 indicadores do resultado de enfermagem “estado respiratório: permeabilidade das vias aéreas”. Resultados: no primeiro dia de avaliação os indicadores mais comprometidos foram: frequência respiratória, tosse, profundidade da respiração e uso de músculos acessórios. Durante o acompanhamento, verificou-se que a maior parte dos indicadores apresentou desvio leve da variação normal e, na última avaliação, houve predomínio de indicadores com algum grau de comprometimento. Conclusões: com auxílio da Classificação dos resultados de enfermagem, observou-se que pacientes submetidos a cirurgias toracoabdominais podem apresentar comprometimento da permeabilidade das vias aéreas mesmo após dias da realização do procedimento cirúrgico.

RESUMEN Objetivos: valorar la evolución de los indicadores clínicos que caracterizan la permeabilidad de las vías aéreas en pacientes en el posoperatorio de cirugías toracoabdominales y evaluar su relación con la ocurrencia del diagnóstico “desobstrucción ineficaz de las vías aéreas”. Métodos: investigación descriptiva, cuantitativa, longitudinal en la cual participaron 60 pacientes que recibieron seguimiento por cinco días. Se utilizaron 11 indicadores del resultado de enfermería “estado respiratorio: permeabilidad de las vías aéreas”. Resultados: en el primer día de evaluación, los indicadores más comprometidos fueron: frecuencia respiratoria, tos, profundidad de la respiración y utilización de músculos accesorios. Durante el seguimiento, se verificó que la mayor parte de los indicadores presentó una leve desviación de la variación normal y, en la última evaluación, hubo un predominio de indicadores con algún grado de comprometimiento. Conclusiones: con la ayuda de la Clasificación de los resultados de enfermería, se observó que los pacientes sometidos a cirugías toracoabdominales pueden presentar comprometimiento de la permeabilidad de las vías aéreas incluso después de algunos días de realizar el procedimiento quirúrgico.

ABSTRACT Objectives: to evaluate the evolution of clinical indicators that characterize airway permeability in patients in the postoperative period of thoracoabdominal surgeries and to analyze their relationship with the occurrence of the diagnosis “ineffective airway clearance”. Methods: descriptive, quantitative, longitudinal research with 60 patients who were followed for five consecutive days. Eleven indicators of the nursing outcome “respiratory status: airway permeability” were used. Results: on the first day of evaluation, the most compromised indicators were: respiratory rate, cough, depth of breath and use of accessory muscles. During follow-up, most of the indicators presented a slight deviation from normal variation and, in the last evaluation, there was a predominance of indicators with some degree of impairment. Conclusions: with the aid of the Nursing Outcomes Classification, it was observed that patients submitted to thoracoabdominal surgeries may present compromised airway permeability even days after surgery.

ABSTRACT Hexapods, commonly known as insects, are a neglected taxonomic group in the Fernando de Noronha archipelago, with unanswered questions about their species richness and the ecological processes in which they are involved (e.g., colonization, introduction, establishment, and extinction). Herein, we provide an updated Hexapod checklist with current nomenclatural combinations. The entomofauna of the Fernando de Noronha archipelago is currently composed of 453 species in 21 orders. The orders, and their respective number of species, are: Blattaria (9), Coleoptera (118), Collembola (29), Dermaptera (3), Diplura (1), Diptera (134), Embioptera (1), Hemiptera (29), Hymenoptera (59), Isoptera (2), Lepidoptera (25), Mantodea (1), Neuroptera (3), Odonata (5), Orthoptera (11), Phasmatodea (1), Phthiraptera (6), Psocoptera (3), Siphonaptera (1), Thysanoptera (10), and Zygentoma (2). The archipelago has 263 new taxon records (family + genera + species). Thirty-eight species (3.39%) were described from local specimens and most of them are likely endemic species. This study more than doubles our knowledge (from the previous 190 records) of the entomofauna in this large Brazilian archipelago. This study also provides a baseline for studies on its conservation status and for implementing future environmental management programs.

Abstract INTRODUCTION The Integrated Program of Leprosy Control was initiated in 2003 in the municipality of Buriticupu, Maranhão, Brazil, an area considered hyperendemic for leprosy. Here, we present the evolution of the indicators of leprosy within the established period in children aged <15 years. METHODS: This is a descriptive study based on an active search for cases and spontaneous healthcare demand for leprosy, with an evolutionary analysis of the detection coefficient of new cases. We considered individuals aged <15 years diagnosed with leprosy from January 2003 to December 2015. To evaluate the factors associated with clinical and operational forms, Chi-square, Fisher’s exact, or Fisher-Freeman-Halton tests were performed. RESULTS A total of 61 new cases were detected (6.9% of the total leprosy cases diagnosed in the municipality during the study period), and the majority was found in males (62.3%). The most frequent operational classification was paucibacillary (67.2%), and this association increased with age. The tuberculoid clinical form was the most prevalent in both sexes and in the age range of 10 to <15 years. There was a reduction in the detection coefficient from 21.84/100,000 inhabitants in 2003 to 2.79/100,000 in 2015. CONCLUSIONS Despite the progress in the control of leprosy, this historical series shows that it is necessary to strengthen educational measures and implement control actions, so that the disease ceases to be a public health problem in the population aged <15 years.

ABSTRACT OBJECTIVE: To analyze the effects of early determinants on adolescent fat-free mass. METHODS: A cohort study with 579 adolescents evaluated at birth and adolescence in a birth cohort in São Luís, Maranhão. In the proposed model, estimated by structural equation modeling, socioeconomic status (SES) at birth, maternal age, pregestational body mass index (BMI), gestational smoking, gestational weight gain, type of delivery, gestational age, sex of the newborn, length and weight at birth, adolescent socioeconomic status, “neither study/nor work” generation, adolescent physical activity level and alcohol consumption were tested as early determinants of adolescent fat-free mass (FFM). RESULTS: A higher pregestational BMI resulted in higher FFM in adolescence (Standardized Coefficient, SC = 0.152; p < 0.001). Being female implied a lower FFM in adolescence (SC = −0.633; p < 0.001). The negative effect of gender on FFM was direct (SC = −0.523; p < 0.001), but there was an indirect negative effect via physical activity level (SC = −0.085; p < 0.001). Women were less active (p < 0.001). An increase of 0.5 kg (1 Standard Deviation, SD) in birth weight led to a gain of 0.25 kg/m2 (0.106 SD) in adolescent FFM index (p = 0.034). Not studying or working had a negative effect on the adolescent's FFM (SC = −0.106; p = 0.015). Elevation of 1 SD in the adolescent's physical activity level represented an increase of 0.5 kg/m2 (0.207 SD) in FFM index (p < 0.001). CONCLUSIONS: The early determinants with the greatest effects on adolescent FFM are gender, adolescent physical activity level, pregestational BMI, birth weight and belonging to the “neither-nor” generation.

Abstract INTRODUCTION: The Integrated Program of Leprosy Control was initiated in the municipality of Buriticupu, Maranhão, Brazil, an area considered hyperendemic for leprosy in 2003. It aims at assessing the clinical and epidemiological characteristics of the disease to reduce the detection rate of new cases until 2015. Here, we present the evolution of the indicators of leprosy within the period from 2003 to 2015. METHODS: We conducted a descriptive analytical study based on the active search for and voluntary referral of cases of leprosy. The detection rate of new cases was analyzed over time. We included individuals diagnosed with leprosy between January 2003 and December 2015. The association between categorical variables was assessed using the chi-square test of independence, considering a level of significance of 5%. When the association was significant, the detection rate (with a confidence interval of 95%) was calculated. RESULTS: Overall, 879 new leprosy cases were detected; the majority of the affected individuals were men (65.9%). Multibacillary leprosy was the most common type of the disease, according to the operational classification (55.5%); it showed the strongest association with an age ≥60 years. We also detected an association between the male sex and both, lepromatous and multibacillary leprosy. The detection rate reduced from 211.09/100,000 population in 2003 to 50.26/100,000 population in 2015. CONCLUSIONS: We found an improvement in leprosy control, with a reduction in the detection rate and the absolute number of cases. Strengthening of disease control measures should be prioritized to eliminate leprosy as a public health concern in this municipality.

Abstract Objective: To evaluate the variation of intraocular pressure and ocular perfusion pressure during hemodialysis sessions, in the pre, intra (hourly) and post dialytic periods, in patients treated at Hemodialysis Reference Services in Fortaleza - CE. Methods: The study was longitudinal and prospective. 45 patients underwent hemodialysis. All patients were recruited to undergo an ophthalmologic examination, in addition to the intraocular pressure measurement with Tonopen. Results: The sample consisted of 26 men and 19 women with a mean age of 51.8 years. The study revealed that there is an important difference between pre and post hemodialysis intraocular pressure, decreasing by an average of 2.59 mmHg. When analyzing ocular perfusion pressure, an average increase of 1.85 mmHg was found between the onset and end of hemodialysis. Conclusion: According to the present study, the hemodialysis process is an apparently safe procedure in relation to altered intraocular pressure and ocular perfusion pressure, as causes of ocular pathologies, mainly glaucoma.

Resumo Objetivo: Avaliar a variação da pressão intraocular e da pressão de perfusão ocular durante sessão de hemodiálise, nos períodos pré, intra (a cada hora) e pós dialítico, em pacientes tratados em Serviços de Referência em hemodiálise da cidade de Fortaleza - CE. Métodos: O estudo foi longitudinal e prospectivo. 45 pacientes foram submetidos à hemodiálise. Todos os pacientes foram recrutados a fazer um exame oftalmológico, além da aferição da pressão intraocular com o Tonopen. Resultados: A amostra foi composta por 26 homens e 19 mulheres com idade média de 51,8 anos. O estudo revelou que há uma diferença importante entre a pressão intraocular pré e pós hemodiálise, diminuindo em média 2,59 mmHg. Ao analisar a pressão de perfusão ocular, foi encontrado um aumento médio de 1,85 mmHg entre o início e o término da hemodiálise. Conclusão: De acordo com o presente estudo, o processo de hemodiálise é um procedimento aparentemente seguro em relação à alteração da pressão intraocular e da pressão de perfusão ocular, como causadores de patologias oculares, principalmente o glaucoma.

This study showed that laboratory markers of recent infection by dengue, Zika or chikungunya arboviruses were detected in the biological samples of approximately one-third of patients with encephalitis, myelitis, encephalomyelitis or Guillain-Barré syndrome, in a surveillance programme in Piauí state, Brazil, between 2015-2016. Fever and myalgia had been associated with these cases. Since in non-tropical countries most infections or parainfectious diseases associated with the nervous system are attributed to herpesviruses, enteroviruses, and Campylobacter jejuni, the present findings indicate that in tropical countries, arboviruses may now play a more important role and reinforce the need for their surveillance and systematic investigation in the tropics.

ABSTRACT OBJECTIVE To analyze the effects of maternal pre-pregnancy body mass index and weight gain during pregnancy on the baby's birth weight. METHODS We conducted a cross-sectional study with 5,024 mothers and their newborns using a Brazilian birth cohort study. In the proposed model, estimated by structural equation modeling, we tested socioeconomic status, age, marital status, pre-pregnancy body mass index, smoking habit and alcohol consumption during pregnancy, hypertension and gestational diabetes, gestational weight gain, and type of delivery as determinants of the baby's birth weight. RESULTS For a gain of 4 kg/m2 (1 Standard Deviation [SD]) in pre-pregnancy body mass index, there was a 0.126 SD increase in birth weight, corresponding to 68 grams (p < 0.001). A 6 kg increase (1 SD) in gestational weight gain represented a 0.280 SD increase in newborn weight, correponding to 151.2 grams (p < 0.001). The positive effect of pre-pregnancy body mass index on birth weight was direct (standardized coefficient [SC] = 0.202; p < 0.001), but the negative indirect effect was small (SC = -0.076, p < 0.001) and partially mediated by the lower weight gain during pregnancy (SC = -0.070, p < 0.001). The positive effect of weight gain during pregnany on birth weight was predominantly direct (SC = 0.269, p < 0.001), with a small indirect effect of cesarean delivery (SC = 0.011; p < 0.001). Women with a higher pre-pregnancy body mass index gained less weight during pregnancy (p < 0.001). CONCLUSIONS The effect of gestational weight gain on the increase in birth weight was greater than that of pre-pregnancy body mass index.

ABSTRACT OBJECTIVE To analyze the effects of maternal pre-pregnancy body mass index and weight gain during pregnancy on the baby's birth weight. METHODS We conducted a cross-sectional study with 5,024 mothers and their newborns using a Brazilian birth cohort study. In the proposed model, estimated by structural equation modeling, we tested socioeconomic status, age, marital status, pre-pregnancy body mass index, smoking habit and alcohol consumption during pregnancy, hypertension and gestational diabetes, gestational weight gain, and type of delivery as determinants of the baby's birth weight. RESULTS For a gain of 4 kg/m2 (1 Standard Deviation [SD]) in pre-pregnancy body mass index, there was a 0.126 SD increase in birth weight, corresponding to 68 grams (p < 0.001). A 6 kg increase (1 SD) in gestational weight gain represented a 0.280 SD increase in newborn weight, correponding to 151.2 grams (p < 0.001). The positive effect of pre-pregnancy body mass index on birth weight was direct (standardized coefficient [SC] = 0.202; p < 0.001), but the negative indirect effect was small (SC = -0.076, p < 0.001) and partially mediated by the lower weight gain during pregnancy (SC = -0.070, p < 0.001). The positive effect of weight gain during pregnany on birth weight was predominantly direct (SC = 0.269, p < 0.001), with a small indirect effect of cesarean delivery (SC = 0.011; p < 0.001). Women with a higher pre-pregnancy body mass index gained less weight during pregnancy (p < 0.001). CONCLUSIONS The effect of gestational weight gain on the increase in birth weight was greater than that of pre-pregnancy body mass index.

ABSTRACT Objective: to evaluate the respiratory status of postoperative adult patients by assessing the nursing outcome Respiratory Status. Method: descriptive, cross-sectional study developed with 312 patients. Eighteen NOC indicators were assessed and rated using a Likert-scale questionnaire and definitions. Descriptive and correlative analysis were conducted. Results: the most compromised clinical indicators were coughing (65.5%), auscultated breath sounds (55%), and respiratory rate (51.3%). Factors associated with worse NOC ratings in specific clinical indicators were sex, age, pain, and general anesthesia. Conclusions: certain clinical indicators of respiratory status were more compromised than others in postoperative patients. Patient and context-related variables can affect the level of respiratory compromise.

RESUMO Objetivo: avaliar o estado respiratório de pacientes adultos no pós-operatório por meio da análise do resultado de enfermagem Estado Respiratório. Método: estudo descritivo e transversal desenvolvido com 312 pacientes. Dezoito indicadores da Classificação dos Resultados de Enfermagem (Nursing Outcomes Classification - NOC) foram avaliados e classificados utilizando um questionário contendo escalas Likert e definições. Foram realizadas análises descritivas e de correlações. Resultados: os indicadores clínicos mais comprometidos foram tosse (65,5%), ausculta de sons respiratórios (55%) e frequência respiratória (51,3%). Fatores associados com escores NOC comprometidos para indicadores clínicos específicos foram gênero, idade, dor e anestesia geral. Conclusões: certos indicadores clínicos do estado respiratório foram mais comprometidos do que outros em pacientes no pós-operatório. O paciente e as variáveis relacionadas aos pacientes e ao contexto podem afetar o nível de comprometimento respiratório.

RESUMEN Objetivo: evaluar el estado respiratorio de pacientes adultos en postoperatorio por la evaluación del resultado de enfermería Estado Respiratorio. Método: estudio descriptivo transversal realizado con 312 pacientes. Dieciocho indicadores de la Clasificación de Resultados en Enfermería (Nursing Outcomes Classification - NOC) fueron evaluados y calificados utilizando un cuestionario conteniendo escalas Likert y definiciones. Análisis descriptivos y de correlaciones fueron realizados. Resultados: los indicadores clínicos más comprometidos fueron tos (65,5%), auscultación de sonidos respiratorios (55%) y frecuencia respiratoria (51,3%). Factores asociados con puntuaciones NOC comprometidas en indicadores clínicos específicos fueron género, edad, dolor y anestesia general. Conclusiones: ciertos indicadores clínicos de estado respiratorio fueron más comprometidos que otros en pacientes postoperatorios. El paciente y las variables relacionadas con el paciente y el contexto pueden afectar el nivel de compromiso respiratorio.

RESUMEN Objetivo Evaluar y comparar la tasa respiratoria y saturación de oxígeno de los pacientes en el postoperatorio inmediato de la laparotomía exploratoria y la colecistectomía. Material y Métodos Se trata de un estudio transversal, cuantitativo con 63 pacientes tratados entre noviembre 2014 a abril 2015. Los datos fueron recolectados a través de un cuestionario estructurado aplicado a los pacientes ingresados en la Clínica Quirúrgica del Hospital Municipal Imperatriz. Los participantes del estudio eran pacientes de ambos sexos, con edades comprendidas entre 18-59 años en el postoperatorio inmediato de la laparotomía exploratoria (Grupo I) y colecistectomía (Grupo II). Del cuestionario se extrajeron los datos de tasa por frecuencia respiratoria (FR) y saturación de oxígeno. Los datos fueron analizados estadísticamente empleando el programa BioEstat 5.0 y prueba de Shapiro-Wilk para la normalidad entre variables, análisis de Mann-Whitney inferencial y la prueba de Spearman para la correlación entre las variables. Se comprobó que no hubo significación estadística en cuanto a los cambios clínicamente relevantes a FR (p=0,4) y los cambios clínicos en saturación de oxígeno (p=0,8) en comparación con las muestras de ambos grupos y los procedimientos quirúrgicos realizados. Los casos en los que se alteraron los valores de ambas variables analizadas, que muestran las condiciones de taquipnea o hipopnea e hipoxemia fueron casos aislados, poco significativos estadísticamente. Conclusión Se encontró que, independientemente de los procedimientos quirúrgicos realizados, el patrón de respiración se mantuvo de normal a mínimamente alterado, no habiendo en estos individuos interferencia directa de estas cirugías en la función respiratoria que causase de forma significativa alteración clínica de la respiración.

RESUMO Objetivo Avaliar e comparar a frequência respiratória e a saturação de oxigênio de pacientes no pós-operatório imediato de laparotomia exploratória e colecistectomia. Material e Método Trata-se de uma pesquisa transversal, quantitativa, com 63 pacientes atendidos entre novembro de 2014 a abril de 2015. Os dados foram coletados por meio de um questionário estruturado aplicado aos pacientes internados na Clínica Cirúrgica do Hospital Municipal de Imperatriz. Participaram do estudo pacientes de ambos os sexos, com faixa etária entre 18 a 59 anos, no pós- operatório imediato de laparotomia exploratória (Grupo I) e colecistectomia (Grupo II). Do questionário foram extraídos dados relacionados frequência respiratória (FR) e saturação de oxigênio (SapO2). Os dados foram analisados estatisticamente empregando-se o programa BioEstat 5.0, bem como teste Shapiro Wilk para normalidade entre variáveis, teste analítico inferencial Mann-Whitney, e teste Spearman para correlação entre variáveis. Resultados Evidenciou-se que não houve significância estatística quanto a alterações clínicas pertinentes a FR (p=0,4) e alterações clínicas da SapO2 (p=0,8) quando comparadas as amostras de ambos os grupos e os procedimentos cirúrgicos realizados. Os casos em que os valores de ambas as variáveis analisadas mostraram-se alterados, evidenciando condições de taquipneia ou bradipneia e hipoxemia foram casos isolados, pouco expressivos estatisticamente. Conclusão Constatou-se que independentemente dos procedimentos cirúrgicos realizados, o padrão respiratório permaneceu normal a minimamente alterado, não havendo, nesses indivíduos interferência direta dessas cirurgias sobre a função respiratória que provocasse de forma significativa alteração clínica da respiração.

ABSTRACT Objective To evaluate and compare the respiratory rate and oxygen saturation of patients in the immediate postoperative period of exploratory laparotomy and cholecystectomy. Material and Method This is a cross-sectional and quantitative study with 63 patients seen between November 2014 and April 2015. Data were collected through a structured questionnaire applied to patients admitted to the Surgical Clinic of the Municipal Hospital of Imperatriz City. Patients of both sexes, aged from 18 to 59 years, in the immediate postoperative period of exploratory laparotomy (Group I) and cholecystectomy (Group II) participated in the study. Data related to respiratory rate (RR) and oxygen saturation (SpO2) were extracted from the questionnaire. Data were analyzed statistically using the BioEstat 5.0 program, as well as Shapiro Wilk test for normality between variables, Mann-Whitney inferential analytical test, and Spearman test for correlation between variables. Results There was no statistical significance regarding the clinical changes of RR (p = 0.4) and clinical changes of SpO2 (p = 0.8) when comparing the samples from both groups and the surgical procedures performed. The cases in which the values of both analyzed variables were altered, evidencing conditions of tachypnoea or bradypnea and hypoxemia, were isolated cases, not statistically significant. Conclusion Regardless of the surgical procedures performed, the respiratory pattern remained normal to minimally altered and, in these individuals, there was no direct interference of these surgeries on the respiratory function that caused a significant clinical alteration of respiration.

Resumo Fundamento: A hipertensão arterial sistêmica (HAS) é uma condição clínica de etiologia multifatorial e de sério agravo à saúde do idoso. Apesar das alterações cardiovasculares influenciarem o desenvolvimento da HAS nesta faixa etária, vários outros fatores genéticos e ambientais têm sido descritos na literatura, incluindo a variante polimórfica do gene da enzima conversora da angiotensina (ECA) e a distribuição da gordura corporal. Objetivo: Avaliar a prevalência da HAS entre idosos e sua possível correlação com a variante polimórfica I/D do gene da ECA e outros fatores de risco associados. Métodos: Estudo de base populacional com 387 idosos residentes na zona urbana de Ibiaí (MG, Brasil) utilizando, para tal, um modelo hierarquizado. Resultados: À análise estatística, a variante polimórfica do gene da ECA não se mostrou associada à HAS (p = 0,316). Por outro lado, mostraram associação significativa com a HAS os fatores: sexo feminino, ausência de companheiro, consumo de mais de uma porção de sal ao dia e alterações nos índices de massa corporal e na relação cintura-quadril. Conclusão: Apesar da variante polimórfica da ECA não ter mostrado influência sobre a prevalência de HAS em idosos, algumas variáveis individuais, socioeconômicas, metabólicas e de hábitos comportamentais mostraram associação com esta condição.

Abstract Background: Hypertension is a clinical condition of multifactorial etiology that imposes serious harm to the health of elderly individuals. Despite the fact that cardiovascular disorders influence the development of hypertension in this age group, several other genetic and environmental factors have been described in the literature, including the polymorphic variant of the angiotensin-converting enzyme (ACE) gene and the distribution of body fat. Objective: To assess the prevalence of hypertension among elderly individuals and its possible correlation with the I/D polymorphic variant of the ACE gene and other associated risk factors. Methods: Population-based study using a hierarchical model and including 387 elderly individuals residing in the urban area of Ibiaí (Minas Gerais, Brazil). Results: On statistical analysis, the polymorphic variant of the ACE gene was not associated with hypertension (p = 0.316). On the other hand, there was a significant association between hypertension and the variables female sex, absence of a partner, consumption of more than one portion of salt per day, and changes in body mass index and waist-to-hip ratio. Conclusion: Although the polymorphic variant of the ACE gene showed no influence on the prevalence of hypertension in elderly individuals, some variables such as individual, socioeconomic, metabolic, and behavioral habits were associated with this condition.

ABSTRACT These guidelines are the result of a joint effort from writing groups of the Brazilian Stroke Society, the Scientific Department of Cerebrovascular Diseases of the Brazilian Academy of Neurology, the Brazilian Stroke Network and the Brazilian Society of Diagnostic and Therapeutic Neuroradiology. Members from these groups participated in web-based discussion forums with predefined themes, followed by videoconference meetings in which controversies and position statements were discussed, leading to a consensus. This guidelines focuses on the implications of the recent clinical trials on endovascular therapy for acute ischemic stroke due to proximal arterial occlusions, and the final text aims to guide health care providers, health care managers and public health authorities in managing patients with this condition in Brazil.

RESUMO Estas diretrizes são o resultado de um esforço conjunto de membros da Sociedade Brasileira de Doenças Cerebrovasculares (SBDCV), Departamento científico de Doenças Cerebrovasculares da Academia Brasileira de Neurologia (ABN), Rede Brasil AVC (RBAVC) e da Sociedade Brasileira de Neurorradiologia Diagnóstica e Terapêutica (SBNR). Membros destas 4 entidades participaram de fórum de discussões por internet de temas pré-definidos, seguidos de encontros de videoconferência para discussão de pontos controversos e das recomendações, em busca de um consenso final. Estas diretrizes tem seu foco sobre as implicações dos recentes ensaios clínicos de tratamento endovascular do acidente vascular cerebral (AVC) isquêmico agudo relacionado a oclusão de artérias proximais. O texto final foi elaborado para servir de orientação no manejo destes pacientes AVC isquêmico pelos diferentes profissionais de saúde, gestores de saúde pública e de saúde complementar no Brasil.