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Croceous glands in Polygala adenophora (Polygalaceae): structure, histochemical, and functional aspects
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JORGE, Augusto César da Silva

; FILGUEIRA, Joana Patrícia Pantoja Serrão

; LOPES, Layse Kristine Corrêa

; AGUIAR-DIAS, Ana Cristina Andrade de

Acta Amazonica

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2024, Volume 54 N. 1 elocation e54bc23109

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Croceous glands are visible structures defined by their rounded shape and yellowish color. They have great taxonomic importance, being used to delimit the Timutua section, one of the 14 sections of the subgenera Polygala, genera Polygala, the most representative of the family Polygalaceae, with about 120 species recorded in Brazil. However, detailed information about the nature of croceous glands is still missing. Thus, this study aimed to characterize the origin, structure, and function of the croceous glands in the floral structures, fruits, leaf blades, and stems of Polygala adenophora. Samples of P. adenophora at different developmental stages (flower buds, fully developed flowers and fruits), as well as stems, and leaves collected from the 1st, 3rd, 6th, and 9th nodes were obtained from a coastal area in Pará state, Brazil. The samples were fixed in FAA50 or buffered neutral formalin and submitted to light microscopy and scanning electron microscopy. Histochemical tests were carried out for lipophilic and hydrophilic compounds. Our results showed that the croceous glands are secretory cavities and ducts of schizolysigenous origin, present since the beginning of the development of vegetative and reproductive organs. The cavities and ducts produce a lipophilic compound consisting of essential oils and lipids. We hypothesize that this exudate possibly has a protective function, acting against pathogen and herbivore attacks.

RESUMO Glândulas cróceas são estruturas visíveis, definidas por seu formato arredondado e coloração amarelada. Elas possuem grande importância taxonômica, sendo utilizadas para delimitar a seção Timutua, uma das 14 seções do subgênero Polygala, pertencente ao gênero Polygala, o mais representativo da família Polygalaceae, com cerca de 120 espécies registradas para o Brasil. Porém, as glândulas cróceas ainda carecem de informações mais detalhadas sobre sua natureza. Dessa forma, o presente estudo caracterizou a distribuição, estrutura e histoquímica das glândulas cróceas nos órgãos reprodutivos e vegetativos aéreos de Polygala adenophora. Amostras de P. adenophora em diferentes estágios de desenvolvimento (botões florais, flores totalmente desenvolvidas e frutos), assim como caule e folhas extraídas dos 1º, 3º, 6º e 9º nós, foram obtidas em uma área costeira no estado do Pará, Brasil. As amostras foram fixadas em FAA50 ou formalina neutra tamponada e submetidas a microscopia de luz e microscopia eletrônica de varredura. Foram realizados testes histoquímicos para substâncias lipofílicas e hidrofílicas. Os resultados mostraram que as glândulas cróceas são formadas por cavidades e ductos secretores, com formação de origem esquizolisígena, presentes desde o início do desenvolvimento dos órgãos vegetativos e reprodutivos. As cavidades e ductos secretam uma substância de natureza lipofílica, composta por óleos essenciais e lipídios. Hipotetizamos que esse exsudato possivelmente tenha uma função protetiva, atuando contra ataques de patógenos e herbívoros.

https://doi.org/10.1590/1809-4392202301091

Healthy lifestyle as predictors of common mental disorder during coronavirus disease
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Castro, Laianne Liliane Pereira Troncha de

; Walsh, Henrique Porcatti

; Accioly, Marilita Falangola

; Martins, Lislei Jorge Patrizzi

; Oliveira, Ana Carolina Otoni

; Graffitti, Lívia Pires Marra

; Pegorari, Maycon Souza

; Walsh, Isabel Aparecida Porcatti de

Revista da Associação Médica Brasileira

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2024, Volume 70 N. 1 elocation e20231004

Abstract: En | Text: En | PDF: En

SUMMARY OBJECTIVE: The objective of the present study was to verify the indication of common mental disorder and changes in healthy lifestyle among individuals affected by coronavirus disease, as well as to evaluate if changes in healthy lifestyle are predictors of common mental disorder. METHODS: This descriptive, cross-sectional study employed an exploratory approach and quantitative methodology, using the Self-Reporting Questionnaire to assess the indication of common mental disorder and questions regarding healthy lifestyle during the pandemic. RESULTS: A total of 280 individuals affected by coronavirus disease, aged 18 years and above, participated in the study. The average indication for common mental disorder was 5.0±5.34. The average age was characterized by adults (41.24±14.03 years), with the majority being women (57.9%), White (51.4%), and those in stable relationships (55.7%). Worsening sleep quality (β==6.327; p<0.001) was the main predictor of common mental disorder, followed by female gender (β==2.814; p<0.001) and worsening dietary habits (β==2.227; p<0.012). CONCLUSION: These factors should be considered in the assessment of individuals affected by coronavirus disease to provide comprehensive care.

https://doi.org/10.1590/1806-9282.20231004

Doença Cardiovascular Aterosclerótica, Necessidades não Satisfeitas, e Inclisiran
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Ferreira, Jorge

; Palma, Isabel

; Moura, José Pereira de

; Gouveia, Miguel

; Corte-Real, Ana Luísa

; Silva, Alberto Mello e

Medicina Interna

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dec 2023, Volume 30 N. 4 Pages 30 - 38

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The leading cause of death and disability worldwide are due to atherosclerotic cardiovascular disease (ASCVD), entailing a heavy economic impact, in Portugal corresponding to 1% of the gross domestic product. The development and progression of ASCVD are closely related to hypercholesterolaemia, with high LDL-C levels being its most important and easily modifiable risk factor. Reducing LDL-C has been shown to decrease the incidence of cardiovascular events and European recommendations advocate LDL-C target values according to the patient's cardiovascular risk. The risk of hypercholesterolaemia is cumulative, making it relevant to reduce LDL-C as early as possible. Despite the efficacy and safety demonstrated by several existing lipid-lowering therapies, in the real world most patients do not achieve the recommended lipid values. Several limita-tions to adequate lipid control have been pointed out, namely the low adherence of patients to treatment. Inclisiran is the first drug to inhibit PCSK9 synthesis through RNA small interference mechanism. With a subcutaneous administration every six months after initial and 3-month dose, it allows a LDL-C reduction higher than 50%, with a good safety profile. The advantage of its long duration of action will potentially overcome the low compliance of patients to treat-ment and increase the effectiveness in reducing LDL-C, which may translate into a reduction in morbidity and mortality from ASCVD and its high economic impact.

Resumo A doença cardiovascular aterosclerótica (DCVA) lidera as principais causas de morte e incapacidade a nível mundial, acarretando um pesado impacto económico, correspondente a 1% do produto interno bruto em Portugal. O desenvolvimento e progressão da DCVA encontra-se em estreita relação com a hipercolesterolemia, sendo que níveis elevados de C-LDL são o seu fator de risco mais importante e facilmente modificável. A redução do C-LDL provou diminuir a incidência de eventos cardiovasculares e as recomendações europeias advogam valores alvo de C-LDL de acordo com o risco cardiovascular do doente. O risco da hipercolesterolemia é cumulativo, tornando-se relevante a redução do C-LDL o mais precocemente possível. Apesar da eficácia e segurança demonstrada pelas diversas terapêuticas hipolipemiantes existentes, no mundo real a maioria dos doentes não atinge os valores lipídicos recomendados. Várias limitações ao adequado controlo lipídico foram apontadas, nomeadamente a baixa adesão dos doentes ao tratamento. Inclisiran é o primeiro fármaco que permite inibir a síntese de PCSK9 através do mecanismo de RNA de interferência. Com uma administração subcutânea semestral, após administração nos dias 1 e 90, possibilita uma redução do C-LDL superior a 50%, com bom perfil de segurança. A vantagem da sua longa duração de ação permitirá potencialmente contornar a baixa adesão dos doentes ao tratamento e aumentar a efetividade na redução do C-LDL, que se poderá traduzir na redução da morbi-mortalidade por DCVA e do seu elevado impacto económico.

https://doi.org/10.24950/rspmi.1603

Use of new technologies in suicide prevention in adolescents: systematic literature review
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Pinho, Ana Maria

; Façanha, Jorge

; Santos, José Carlos

Millenium - Journal of Education, Technologies, and Health

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dec 2023, N. 22 elocation e28551

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Introducción: El suicidio es una de las principales causas de muerte en adolescentes. En la evaluación del riesgo la tecnología está ganando terreno. Los adolescentes son usuarios experimentados de las tecnologías, lo que justifica intervenciones para la prevención del suicidio basadas en nuevas tecnologias. Objetivo: Identificar los beneficios del uso de nuevas tecnologías en la prevención del riesgo de suicidio en adolescentes. Métodos: Revisión sistemática de la literatura. Búsqueda realizada en bases de datos EBSCOhost y PubMed. Artículos incluidos según recomendaciones PRISMA. Se utilizó la conjugación booleana con descriptores en inglés: technolog* AND (APP OR application OR mobile application) AND (suicid*) AND (adolescent OR youth OR pubertad). Resultados: 11 artículos cumplieron los criterios de inclusión y elegibilidad. Aplicaciones móviles o APP y detección de idioma fueron las tipologías encontradas, siendo las Aplicaciones para Smartphone/APP presentes en el mayor número de estudios. Los resultados demuestran la importancia del uso de nuevas tecnologías para prevenir el riesgo de suicidio. Conclusión: Se evidenció alta adherencia al uso de nuevas tecnologías, útiles en la prevención del riesgo de suicídio en adolescentes. Las nuevas tecnologías se consideraron bien aceptadas y tienen efectos beneficiosos. Hasta el momento, los datos escasos respaldan el uso de estas intervenciones en la práctica clínica. El número de estudios sobre este tema es limitado, lo que requiere más investigaciones.

Abstract Introduction: Suicide is one of the main causes of death in adolescents. In assessing suicide risk, technology is gaining ground. Adolescents have experienced users of technology, justifying interventions based on new technologies in suicide prevention. Objective: To identify the benefits of using new technologies to prevent suicide risk in adolescents. Methods: Systematic literature review. The research was performed in EBSCOhost and PubMed databases. Included articles according to PRISMA recommendations. Boolean conjugation with descriptors in English was used: technology* AND (APP OR application OR mobile application) AND (suicide*) AND (adolescent OR youth OR puberty). Results: 11 articles met the inclusion and eligibility criteria. Mobile applications or APPs and language detection were the typologies found, with Smartphone Applications/APPs present in a greater number of studies. The results prove the importance of using new technologies to prevent the risk of suicide in adolescents. Conclusion: Evidence demonstrated an elevated adhesion to the use of new technologies, useful in preventing the risk of suicide by adolescents. The new technologies were considered to be well-accepted and have beneficial effects. Presently, there is insufficient data to support the use of these interventions in clinical practice. The number of studies on this topic is limited, requiring further investigation.

Resumo Introdução: O suicídio é uma das principais causas de morte em adolescentes. Na avaliação do risco de suicídio, a tecnologia está a ganhar terreno. Os adolescentes são utilizadores experientes de tecnologias, justificando intervenções baseadas em novas tecnologias na prevenção do suicídio. Objetivo: Identificar os benefícios da utilização de novas tecnologias na prevenção do risco de suicídio em adolescentes. Métodos: Revisão sistemática da literatura. Pesquisa efetuada em bases de dados EBSCOhost e PubMed. Incluídos artigos de acordo com as recomendações PRISMA. Utilizada a conjugação booleana com descritores em língua inglesa: technolog* AND (APP OR application OR mobile application) AND (suicid*) AND (adolescent OR youth OR puberty). Resultados: 11 artigos cumpriram os critérios de inclusão e elegibilidade. Os aplicativos móveis ou APP e a deteção da linguagem foram as tipologias encontradas sendo os Aplicativos/APP para smartphone presentes em maior número de estudos. Os resultados comprovam a importância da utilização das novas tecnologias na prevenção do risco de suicídio em adolescentes. Conclusão: Verificou-se evidência acerca da elevada adesão na utilização de novas tecnologias, úteis na prevenção do risco de suicídio, por parte dos adolescentes. As novas tecnologias foram consideradas bem aceites e acarretam efeitos benéficos. Até ao momento, escassos dados suportam a utilização destas intervenções na prática clínica. O número de estudos sobre esta temática é limitado, sendo necessária a realização de mais investigações.

https://doi.org/10.29352/mill0222.28551

Dysphagia Aortica: An Uncommon and Potentially Life-Threatening Condition
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Vara-Luiz, Francisco

; Fernandes, Eduardo

; Barbosa, Fábio Pé D’Arca

; Albuquerque, Ana

; Marques, Ana Valada

; Fonseca, Jorge

GE-Portuguese Journal of Gastroenterology

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dec 2023, Volume 30 N. 6 Pages 66 - 68

Abstract: En | Text: En | PDF: En

https://doi.org/10.1159/000528108

[SciELO Preprints] - HOW DOES CYCLIN D1 BEHAVIOR AS A BIOMARKER IN PAPILLIFEROUS THYROID CARCINOMAS AND MULTINODULAR GOITERS?
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Bartolomei , Ivan José Paredes Ribas, Carmen Austrália Paredes Marcondes Zella , Maria Augusta Karas Waaga-Gasser, Ana Maria Gasser, Martin Czeczko , Nicolau Gregori Nassif , Paulo Afonso Nunes Manso , Jose Eduardo Ferreira Torres , Orlando Jorge Martins

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Publication date: 2023-12-19

Abstract: En Pt

Introduction: Papillary carcinomas are the most prevalent and least aggressive thyroid carcinomas (PTC). In some cases, the diagnosis is doubtfull and the prognosis is poor. The search for tissue biomarkers that ensure both the diagnosis for indeterminate cases and the prognosis, identifying the most aggressive cases, has been studied in recent decades. Objective: To review the literature in search of cyclin D1 as a marker of papillary thyroid carcinomas and multinodular goiters and evaluate whether its expression correlates with the clinicopathological characteristics of papillary thyroid carcinomas. Methods: Narrative review carried out by collecting information for reading and analysis from online research on virtual platforms. Initially, a search was carried out from MESH descriptors related to the topic, using the following terms: “papillary thyroid carcinoma, cyclin D1, immunohistochemistry, diagnosis, prognosis.” with AND or OR search, considering the title and/or abstract and those chosen were read in full. Results: The search included 77 articles that were compiled in this review. Conclusion: Cyclin D1 was expressed in the vast majority of PTCs, with diffuse distribution being predominant. There was no correlation between its expression and any clinicopathological characteristic of PTC.

Racional - Os carcinomas papilíferos são os mais prevalentes e menos agressivos de tireoide (CPT). Em alguns casos, o diagnóstico é duvidoso e o prognóstico ruim. A busca de biomarcadores teciduais que permitam assegurar tanto o diagnóstico para casos indeterminados, quanto o prognóstico, identificando os casos de maior agressividade, têm sido estudadas nas últimas décadas. Objetivo: Revisar na literatura na busca da ciclina D1 como marcador dos carcinomas papilíferos de tireoide e nos bócios multinodulares, e avaliar se a expressão dela apresenta correlação com as características clínico-patológicas dos carcinomas papilíferos de tireoide. Métodos: Revisão narrativa feita colhendo informações para leitura e análise a partir de pesquisa online em platoformas virtuais. Inicialmente foi realizada busca por descritores DECs relacionados ao tema, utilizando os seguintes termos: “carcinoma papilífero de tireoide, ciclina D1, imunoistoquímica, diagnóstico, prognóstico.” com busca AND ou OR, considerando o título e/ou resumo e os escolhidos foram lidos na íntegra. Resultados: A busca incluiu 77 artigos que foram compilados nesta revisão.  Conclusão: A ciclina D1 foi expressa na grande maioria dos CPT sendo a distribuição difusa predominante. Não houve correlação entre a expressão dela com qualquer característica clinicopatológica dos CPT.

https://doi.org/10.1590/SciELOPreprints.7751

Prácticas pedagógicas interculturales: un estudio etnográfico en escuelas multiculturales de Bogotá
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Posada Escobar, Jorge Jairo

; Rozo Sandoval, Ana Claudia

Revista latinoamericana de estudios educativos

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dec 2023, Volume 53 N. 3 Pages 71 - 95

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Este artículo presenta una investigación realizada con el propósito de caracterizar las prácticas pedagógicas interculturales de tres instituciones de educación pública en las cuales conviven estudiantes de la ciudad de Bogotá con estudiantes indígenas, afro y migrantes. La investigación se realizó desde la perspectiva de etnografía escolar crítica para identificar posibilidades, desafíos y contribuciones a la configuración de las pedagogías interculturales. El trabajo mostró el compromiso pedagógico-político de los docentes, implícito en sus prácticas; las apuestas por una formación en perspectiva humanista, histórica y crítica; la valoración de metodologías planteadas desde “la experiencia vivida” como forma de aproximación de los estudiantes a problemáticas sociales y culturales contemporáneas. Se reivindica la importancia de pensar la relación escuela-comunidad en diálogo con identidades y saberes invisibilizados para transitar hacia pedagogías interculturales para todos y todas.

Abstract This article presents an investigation carried out to characterize the intercultural pedagogical practices of three public education institutions in which students from the city of Bogotá coexist with indigenous, Afro, and migrant students, the investigation was carried out from the perspective of critical school ethnography to identify possibilities, challenges and contributions to the configuration of intercultural pedagogies. The work showed the pedagogical/political commitment of the teachers, implicit in their practices; the bets for a formation in humanist, historical, and critical perspective; the assessment of methodologies raised from “lived experience” as a way of approaching students to contemporary social and cultural problems. The importance of thinking about the school-community relationship in dialogue with invisible identities and knowledge is claimed to move towards intercultural pedagogies for all.

https://doi.org/10.48102/rlee.2023.53.3.579

Natural spawning of the leopard grouper (Mycteroperca rosacea) in captivity in La Paz, Mexico
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Gracia-López, Vicente

; Maldonado-García, Minerva Concepción

; Quiñones-Arreola, Marcos Fabián

; Sandoval-Soto, Jorge León

; Encarnación-Ramírez, Francisco Javier

; Trasviña-Moreno, Ana Gabriela

; García-González, Gerardo Arturo

Ciencias marinas

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dec 2023, Volume 49 elocation e3332

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Natural spawning of the leopard grouper (Mycteroperca rosacea) was studied in captivity from 2004 to 2008 under natural photoperiod conditions. Fish spawned naturally in 2006, but only 90,000 unfertilized eggs were collected. A total of 43 and 27 spawning days were observed in 2007 and 2008, respectively. Spawning season began in March and lasted until May-June and was related to an increase in water temperature from 21.1 to 23.8 °C. The mean (SE) number of eggs released each day was 101,705 (13,876) in 2007 and 40,510 (7,874) in 2008, and the total number of eggs collected in 2007 and 2008 was 4.37 × 106and 1.07 × 106, respectively. The number of eggs collected per month was not significantly different within each year (P> 0.05), although a significant difference was observed between 2007 and 2008 (P< 0.05). The annual relative number of eggs released was 288,750 eggs·kg-1in 2007 and 72,919 eggs·kg-1in 2008, and viable egg production was 184,800 eggs kg-1in 2007 and 25,375 eggs kg-1in 2008. The fertilization rate (%) of the eggs collected daily differed significantly throughout the spawning season of 2007 (P< 0.05). The fertilization rate also differed (P< 0.05) between 2007 (61.10%) and 2008 (32.30%). Statistical analysis of the 2 consecutive spawning seasons indicated no correlation between the fertilization rate and fecundity. The effect of the moon phase on spawning was also considered. The fish spawned at dusk before total darkness. Mean (SD) egg diameter was 864.0 ± 22.0 µm.

Resumen Se estudió el desove natural de la cabrilla sardinera,Mycteroperca rosacea, en cautiverio, de 2004 a 2008 en condiciones naturales de luz y temperatura. Los peces desovaron naturalmente en 2006, pero solo se recolectaron 90,000 huevos no fertilizados. Se observó un total de 43 días de desove en 2007 y 27 días en 2008. La temporada de desove comenzó en marzo y se prolongó hasta mayo-junio, lo cual se relacionó con un aumento en la temperatura del agua de 21.1 a 23.8 °C. La media (error estándar) del número de huevos liberados diariamente fue de 101,705 (13,876) en 2007 y 40,510 (7,874) en 2008, y el número total de huevos recolectados fue de 4.37 × 106y 1.07 × 106, respectivamente. El número de huevos recolectados por mes no fue significativamente diferente dentro de cada año (P> 0.05), pero sí al comparar 2007 y 2008 (P< 0.05). La puesta relativa anual fue de 288,750 huevos·kg-1en 2007 y 72,919 huevos·kg-1en 2008, y la producción de huevos viables fue de 184,800 huevos·kg-1en 2007 y 25,375 huevos·kg-1en 2008. La tasa de fertilización (%) de los huevos recolectados diariamente fue significativamente diferente a lo largo de la temporada de desove de 2007 (P< 0.05). La tasa de fertilización también difirió significativamente (P< 0.05) entre 2007 (61.10%) y 2008 (32.30%). El análisis estadístico indicó que no hubo correlación entre la tasa de fertilización y el número de huevos liberados en ambas temporadas de desove. El efecto de la luna sobre el desove también se analiza en el documento. Durante todo el estudio, los peces desovaron al anochecer antes de la oscuridad total. El diámetro medio (± desviación estándar) del huevo fue de 864.0 ± 22.0 µm.

https://doi.org/10.7773/cm.y2023.3332

Social expectancy increases skin conductance response in mobile instant messaging users
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Ruiz-Ruano García, Ana María

; Sánchez-Kuhn, Ana

; Flores, Pilar

; López Puga, Jorge

Psicothema

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dec 2023, Volume 35 N. 4 Pages 414 - 422

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen: Antecedentes: La sociedad está presenciando dos fenómenos paralelos: el incremento mundial de usuarios de teléfonos móviles y una preocupación creciente por el uso problemático de estos dispositivos. Los modelos teóricos explicativos sugieren que la recompensa social podría explicar parte del uso problemático del teléfono móvil. Dado que la evidencia experimental sobre el impacto que lo social tiene en este fenómeno es limitada, el impacto de la expectativa social sobre el arousal emocional fue analizada mientras se usó mensajería instantánea. Método: Una muestra de 86 estudiantes se asignó aleatoriamente a dos grupos. Los participantes del grupo experimental enviaron un mensaje generador de expectativa social a sus contactos más activos usando su red social preferida. Tras un periodo de distracción, a respuesta electrodérmica de la piel se midió al usar y retirar el móvil. Resultados: El grupo experimental mostró mayores niveles de arousal. El análisis de picos muestra una mayor amplitud en el grupo experimental cuando se usó y se retiró el móvil. Un tiempo de recuperación medio más largo se observó en el grupo experimental al usar el móvil. Conclusiones: La expectativa social es una variable crítica para conceptualizar el uso problemático del móvil y debería considerarse en contextos clínicos.

Abstract: Background: Society is witnessing two parallel phenomena: an increase in the number of mobile phone users worldwide and a growing concern about problematic smartphone use. Leading explanatory models suggest that social reward may explain some problematic smartphone use. Given that experimental evidence about the impact of social variables on problematic smartphone use is scarce, the impact of social expectancy on emotional arousal measured with skin conductance response (SCR) was analysed during instant messaging. Method: A sample of 86 undergraduate students were randomly assigned to two groups. Experimental group participants were instructed to send a social expectation-generating message to their more active contacts in their preferred social network. After experiencing a virtual reality distraction environment, participants' SCR was measured when they were allowed to use the smartphone and when it was withdrawn. Results: Participants in the experimental group showed a higher SCR response than the control group. Peaks analysis also showed that peak amplitude was higher in experimental participants when their smartphones were used and withdrawn. Experimental participants also showed a longer half recovery time when using the smartphone. Conclusions: Social expectancy is a critical variable in understanding problematic smartphone use and it should be considered in clinical contexts.

https://doi.org/10.7334/psicothema2022.362

10.

Posicionamento do Departamento de Imagem Cardiovascular da Sociedade Brasileira de Cardiologia sobre o Uso do Strain Miocárdico na Rotina do Cardiologista – 2023
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Almeida, André Luiz Cerqueira

; Melo, Marcelo Dantas Tavares de

; Bihan, David Costa de Souza Le

; Vieira, Marcelo Luiz Campos

; Pena, José Luiz Barros

; Del Castillo, José Maria

; Abensur, Henry

; Hortegal, Renato de Aguiar

; Otto, Maria Estefania Bosco

; Piveta, Rafael Bonafim

; Dantas, Maria Rosa

; Assef, Jorge Eduardo

; Beck, Adenalva Lima de Souza

; Santo, Thais Harada Campos Espirito

; Silva, Tonnison de Oliveira

; Salemi, Vera Maria Cury

; Rocon, Camila

; Lima, Márcio Silva Miguel

; Barberato, Silvio Henrique

; Rodrigues, Ana Clara

; Rabschkowisky, Arnaldo

; Frota, Daniela do Carmo Rassi

; Gripp, Eliza de Almeida

; Barretto, Rodrigo Bellio de Mattos

; Silva, Sandra Marques e

; Cauduro, Sanderson Antonio

; Pinheiro, Aurélio Carvalho

; Araujo, Salustiano Pereira de

; Tressino, Cintia Galhardo

; Silva, Carlos Eduardo Suaide

; Monaco, Claudia Gianini

; Paiva, Marcelo Goulart

; Fisher, Cláudio Henrique

; Alves, Marco Stephan Lofrano

; Grau, Cláudia R. Pinheiro de Castro

; Santos, Maria Veronica Camara dos

; Guimarães, Isabel Cristina Britto

; Morhy, Samira Saady

; Leal, Gabriela Nunes

; Soares, Andressa Mussi

; Cruz, Cecilia Beatriz Bittencourt Viana

; Guimarães Filho, Fabio Villaça

; Assunção, Bruna Morhy Borges Leal

; Fernandes, Rafael Modesto

; Saraiva, Roberto Magalhães

; Tsutsui, Jeane Mike

; Soares, Fábio Luis de Jesus

; Falcão, Sandra Nívea dos Reis Saraiva

; Hotta, Viviane Tiemi

; Armstrong, Anderson da Costa

; Hygidio, Daniel de Andrade

; Miglioranza, Marcelo Haertel

; Camarozano, Ana Cristina

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Siqueira, Maria Eduarda Menezes de

; Torreão, Jorge Andion

; Rochitte, Carlos Eduardo

; Felix, Alex

Arquivos Brasileiros de Cardiologia

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dec 2023, Volume 120 N. 12 elocation e20230646

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230646

11.

Digital Disconnection and Portuguese Youth: Motivations, Strategies, and Well-Being Outcomes
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Dias, Patrícia

; Martinho, Leonor

; Jorge, Ana

Comunicação e Sociedade

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dec 2023, Volume 44 elocation e023014

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract As most individuals become digital media users, many struggle to find balance in such use. This study adds to emergent research on how digital disconnection experiences reflect on wellbeing (Nguyen et al., 2021; Radtke et al., 2022; Vanden Abeele, 2021) by focusing on motivations and strategies to disconnect from digital media, as well as on outcomes for well-being. We set out to understand teenagers who have voluntarily chosen to disconnect in the post-lockdown period in 2021. Our qualitative study included 20 participants from Portugal between 15 and 18 years old. Among those who consciously chose to disconnect from digital media, motivations arose from realizing that digital media was not bringing enough benefits for the amount of time that they took from users. Specific forms of digital media stood out as particularly problematic for young people, especially social media, but also videogames and pornography. This realization seems to be strongly influenced by the media and is evident in the vocabulary and associations used by our respondents. Social pressure is felt both as causing anxiety when they are connected and when they are disconnected through fear of missing out. However, the group provides support when they engage in a progressive disconnection together. Radical disconnection is rare, especially during the pandemic, and can appear as a solution to a dramatic problem in young people’s lives, but it can also be reverted. More often, participants attempted to self-regulate their use of digital when they acknowledged the advantages of those services as well as their drawbacks. This is not a linear process but rather filled with attempts and reversals as unexpected feelings such as boredom arise. When young people grow different leisure and social habits, they experience positive outcomes of disconnecting from the digital.

Resumo À medida que a maioria dos indivíduos se torna utilizador dos média digitais, muitos lutam para encontrar um equilíbrio nesse uso. Este estudo contribui para a pesquisa emergente sobre como as experiências de desconexão digital se refletem no bem-estar (Nguyen et al., 2021; Radtke et al., 2022; Vanden Abeele, 2021), concentrando-se nas motivações e estratégias para se desconectar dos média digitais, bem como nos resultados para o bem-estar. Propusemo-nos compreender os adolescentes que optaram voluntariamente por desligar no período pós-confinamentos, em 2021. O nosso estudo qualitativo incluiu 20 participantes entre os 15 e os 18 anos em Portugal. Entre aqueles que optaram conscientemente por se desconectar dos média digitais, as motivações surgiram da perceção de que esses meios não traziam benefícios suficientes para a quantidade de tempo que lhes tomavam. Algumas formas específicas de média digitais destacaram-se como particularmente problemáticas para os jovens, especialmente os média sociais, mas também os videojogos e a pornografia. Essa perceção parece ser fortemente influenciada pelos média, o que se evidencia no vocabulário e nas associações usadas pelos entrevistados. A pressão social é sentida como causadora de ansiedade quando estão conectados e quando estão desconectados por meio do fear of missing out (medo de perder o que se está a passar). No entanto, o grupo é fonte de apoio quando eles se envolvem numa desconexão progressiva em conjunto. A desconexão radical é rara, principalmente em tempos de pandemia, e pode aparecer como solução para um problema dramático na vida dos jovens, mas também pode ser revertida. Mais frequentemente, os participantes tentaram autorregular o seu uso do digital, quando reconheceram as vantagens desses serviços, bem como as suas desvantagens. Este não é um processo linear, mas sim marcado por tentativas e reversões, à medida que surgem sentimentos inesperados, como o tédio. Quando os jovens desenvolvem diferentes hábitos sociais e de lazer, experimentam resultados positivos de desconexão do digital.

https://doi.org/10.17231/comsoc.44(2023).4466

12.

Core curriculum in cariology for dentistry degrees in the Republic of Argentina
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Carletto-Kórber, Fabiana PM

; Sorazabal, Ana

; Medici, Silvia

; Ali, Sofía

; Barrionuevo, Alejandra

; Cardozo, Juana

; Cucchi, Analía

; D'Eramo, Luciana

; Escandriolo, Jorge

; Fontanetti, Pablo

; García, Shirley

; Lombardo, Adriana

; Mardenlli, Alejandra

; Masoli, Carla

; Mulbany, Patricia

; Pereira, Lía

; Pérez, Silvia

; Preliasco, Mariana

; Rossi, Glenda

; Squassi, Aldo

; Ulloque, Jorgelina

; Vaculik, Patricia

; Ventrera, Verónica

; Bordoni, Noemí

; Giacaman, Rodrigo A

Acta Odontológica Latinoamericana

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dec 2023, Volume 36 N. 3 Pages 183 - 190

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Aim To prepare a consensus document of the cariology contents and competences included in the curriculum for the dentistry degree at Argentine dental faculties/schools Materials and Method Planning the process in stages: Stage 1- Diagnosis of the situation (Google Form) and invitation to participate extended to the 20 academic units (AU) that offer dentistry degrees. Stage 2- Assessment process of Content (C) and Competences (I) agreements in the five domains: D1 Basic Sciences, D2 Risk and diagnosis of dental caries, D3 Decision-making for non-invasive treatments, D4 Decision-making for invasive treatment, and D5 Evidence-based cariology at community level. Stage 3- Consensus. Stages 2 and 3 were held in Workshop format in virtual mode (W) Results Stage 1- Of the total 20 Google forms sent to the AU, 13 responses were received: 7 from National Universities and 6 from Private Universities. All participants agreed to be part of the consensus. Stage 2- W: 20 representatives from 10 AU participated. It began with a contextualizing conference, after which the representatives were divided into 5 groups to assess the agreements of each D. Stage 3- The Cariology Curriculum document was organized into 5 Domains, and 23 C and 31 I of clinical application were defined for teaching cariology. The contents and competences for each domain were agreed upon. The final document was sent to all W participants for their approval and dissemination in each AU involved Conclusion Cariology contents were defined for dentistry students at Universities in the Argentine Republic.

RESUMEN Objetivo Elaborar un documento de consenso de los contenidos y competencias de cariología en el currículo para las facultades/escuelas de odontología argentinas, a nivel del grado Materiales y Método El proceso de creación se efectuó en etapas: 1- Diagnóstico de situación (Formulario electrónico) e invitación a participar a las 20 unidades académicas (UA) donde se imparte la carrera de odontología. 2- Proceso de valoración de acuerdos de Contenidos (C) y Competencias (I) en los cinco dominios (D): D1: Ciencias Básicas; D2: Riesgo y diagnóstico de caries dental; D3: Toma de decisiones tratamientos no invasivos; D4: Toma de decisiones para el tratamiento invasivo y D5: Cariología basada en la evidencia a nivel comunitario. 3- Etapa de consenso. Las etapas 2 y 3 se efectuaron en formato de Workshop en modalidad virtual (W) Resultados Etapa 1: Del total de 20 formularios enviados a las UA se recibieron 13 respuestas (65%), 7 (53,8%) de Universidades Nacionales y 6 (46,1%) de gestión Privada. El 100% de los participantes estuvieron de acuerdo en formar parte del consenso. Etapa 2: W: Participaron 20 representantes de 10 UA. El proceso se inició con una conferencia contextualizadora, posteriormente los representantes fueron divididos en 5 grupos para la valoración de acuerdos de cada D. Etapa 3: El documento de658. 658.l Currículo en Cariología se organizó en 5 Dominios. Se definieron 23 C y 31 I de aplicación clínica para la enseñanza de la Cariología. Se consensuaron los contenidos y las competencias para cada uno de los dominios. El documento final fue enviado a todos los participantes del W para su aprobación y difusión en cada una de las UA involucradas Conclusión En base al trabajo realizado se determinó un consenso de competencias y contenidos en cariología para estudiantes de grado de Odontología, de las Universidades de la República Argentina.

https://doi.org/10.54589/aol.36/3/183

13.

Linfadenopatías generalizadas como manifestación inicial de lupus eritematoso sistémico: a propósito de un caso clínico
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Raad-Sarabia, María

; Beltran-Hoyo, Gabriel

; Hernandez-Pino, Kewin

; Acosta-Buelva, Jorge

; Chamorro-Acevedo, Katty

; Rico-Fontalvo, Jorge

; Vasquez-Jimenez, Lourdes Carolina

Revista Paraguaya de Reumatología

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dec 2023, Volume 9 N. 2 Pages 76 - 80

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La presencia de linfadenopatías generalizadas se ha asociado de forma usual con lupus eritematoso sistémico (LES), sin embargo, no es usual encontrar este hallazgo como manifestación inicial de la enfermedad. Existen múltiples diagnósticos diferenciales que incluyen la linfadenitis necrotizante histiocítica de Kikuchi, la enfermedad de Castleman, infecciones y el linfoma cuando se presenta este hallazgo como síntoma inicial de LES. Presentamos el caso de un hombre de 56 años que se presentó con 2 meses de linfadenopatía generalizada sin datos al examen o antecedentes que sugirieran diagnóstico de LES; se sospechó inicialmente linfoma o enfermedad infecciosa y se realizó un estudio exhaustivo incluido biopsia de ganglio cervical. La investigación de laboratorio finalmente reveló leucopenia, proteinuria significativa, ANA y anti-dsDNA positivos e hipocomplementemia, lo que confirma el diagnóstico de enfermedad autoinmune tipo LES. Este caso ilustra la importancia de reconocer esta forma de presentación inusual, dado que se trata de una enfermedad potencialmente fatal.

Abstract The presence of generalized lymphadenopathy has usually been associated with systemic lupus erythematosus (SLE), however, it is not usual to find this finding as an initial manifestation of the disease. There are multiple differential diagnoses that include Kikuchi histiocytic necrotizing lymphadenitis, Castleman disease, infections and lymphoma when this finding is presented as an initial symptom of SLE. We present the case of a 56-year-old man who presented with 2 months of generalized lymphadenopathy without examination findings or history suggesting a diagnosis of SLE; Lymphoma or infectious disease was initially suspected and an exhaustive study was performed, including cervical lymph node biopsy. Laboratory investigation finally revealed leukopenia, significant proteinuria, positive ANA, positive anti-dsDNA, and hypocomplementemia, confirming the diagnosis of SLE-type autoimmune disease. This case illustrates the importance of recognizing this unusual presentation, given that it is a potentially fatal disease.

https://doi.org/10.18004/rpr/2023.09.02.76

14.

Estudio multicéntrico sobre multimorbilidad en internados en áreas clínicas
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Valdez, Pascual Rubén

; Leff, Darío

; Wacker, Julio

; Odzak, Andrea

; Cámera, Luis

; Fiori, Mauricio Javier

; Chinen, Jorge

; Daher, José

; Caravelo, Oscar

; Fernández, Diana

; Cruciani, Adrián

; Pérez, Carlos

; Vanzetti, Cecilia

; Calvo, Martina

; Kuschner, Pablo

; Panigadi, Cristian

; Castro, Paula

; Cantillo, Ana

; Aspiazu, Miguel Blanco

Revista Cubana de Medicina

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dec 2023, Volume 62 N. 4 elocation e3370

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

RESUMEN Introducción: El estudio de la comorbilidad requiere de un enfoque multilateral con vistas a mejorar la calidad de la atención de los enfermos por el sistema de atención. Objetivos: Explorar la magnitud de la comorbilidad de enfermedades crónicas en adultos internados en los hospitales. Métodos: Se realizó un estudio prospectivo-observacional-longitudinal-analítico. Se incluyeron pacientes internados en las Salas de Clínica Médica o pacientes clínicos en Salas de Internación Indiscriminada. Se realizó un estudio multicéntrico en 42 centros en un período de 2 años, con un muestreo consecutivo. Para el estudio se tuvo en cuenta la estadística descriptiva, inferencial y de regresión. Resultados: El total de pacientes en el estudio fue de 5925, masculinos con el 50,3 % de edad 60,66 ± 0,25 años. Principal procedencia desde la guardia el 73 %. La estadía hospitalaria de 12,61 ± 0,24 días, mayormente en pacientes quirúrgicos (15,45 ± 0,67 vs 11,76 ± 0,23; p < 0,00001). El 23 % recibió tratamiento quirúrgico. El principal nivel educativo: secundario completo 21,6 %. Dificultades económicas: 20 %, mortalidad 9,26 %; prevalencia de dislipemia, diabetes e hipertensión: 22,53 %; 28,82 % y 51,86 % con 473 nuevos diagnósticos, IMC: 27,88 ± 0,65, Charlson global 2,09 ± 0,02 y en óbitos 3,84 ± 0,11. La media de patologías por paciente fue de 2,14 ± 0,01 y aumentó con la edad (p valor regresión lineal < 0,00001). Conclusiones: La hipertensión, la diabetes y la dislipemia representaron las entidades más prevalentes en Salas de Internación Clínica, Las enfermedades cardiovasculares, respiratorias, infectológicas, oncológicas, neurológicas, metabólicas y nefrológicas fueron predictores independientes de mortalidad.

ABSTRACT Introduction: The study of comorbidity requires a multilateral approach with a view to improving the quality of care for these patients by the care system. Objectives: To explore the magnitude of the comorbidity of chronic diseases in adults admitted to hospitals. Methods: Prospective-observational-longitudinal-analytical study. Patients hospitalized in a medical clinic room or clinical patients in indiscriminate hospitalization rooms are included, Multicenter study in 42 centers, with 2 years of recruitment. Consecutive sampling. Descriptive, inferential and regression statistics. Results: 5925 recruited, male gender 50,3%, age 60,66 ± 0,25 years, main origin from the guard 73%, stay 12,61 ± 0,24 days, longer in surgical (15,45 ± 0,67 vs 11,76 ± 0,23, p < 0,00001), 23% received surgical treatment. Main educational level: complete secondary school 21,6%. Economic difficulties: 20%, mortality 9,26%, prevalence of dyslipidemia, diabetes and hypertension: 22,53%, 28,82% and 51,86% with 473 new diagnoses in said pathologies, BMI: 27,88 ± 0,65, Global Charlson 2,09 ± 0,02 and in deaths 3,84 ± 0,11. The average number of pathologies per patient was 2,14 ± 0,01 and increased with age (p value for linear regression < 0,00001). Conclusions: Hypertension, diabetes and dyslipidemia represented the most prevalent entities in the clinical hospitalization room, cardiovascular, respiratory, infectious, oncological, neurological, metabolic and nephrological diseases were independent predictors of mortality.

15.

Incremental Hemodialysis: A Road to a Greener and Personalized Nephrology
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Martins, Ana Cristina

; Francisco, Diogo

; Azinheira, Jorge

; Laranjinha, Ivo

; Matias, Patrícia

; Gonçalves, Margarida

Portuguese Journal of Nephrology & Hypertension

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sep 2023, Volume 37 N. 3 Pages 139 - 142

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Healthcare facilities are among the greatest contributors to resource consumption and waste generation. Nephrology is one of the most polluting medical areas, mostly due to hemodialysis (HD). Incremental hemodialysis (iHD) has gained attention due to several clinical advantages, by decreasing the number of sessions while the patient still has residual kidney function. Beyond these benefits, this regímen might also be both more economical and environmentally friendly. The aim of this study was to evaluate the potential reduction of resource consumption, waste generation and carbon footprint associated with the implementation of iHD. Methods: We conducted a single-center retrospective analysis of 157 incidental patients initiating HD in our centre in 2019 (pre-pandemic). Retrospectively, a set of criteria identifying eligibility for an iHD program were applied to those patients. Results: Twenty-three patients (15%) would have been eligible for iHD instead of starting a standard HD program. In that scenario, iHD implementation would have reduced from 36 to 85 tons of CO2 equivalent emissions and 4186 kg of contaminated waste yearly, at our unit. iHD would also allow savings of almost 60 000€ and a reduction in water consumption of 418 600 L in one year. Conclusion: This study shows that iHD can significantly attenuate the environmental and economic impact of HD. These findings encourage kidneycare programs and policymakers to adopt greener options but should never be detrimental to the clinical decision of referencing a patient to iHD.

https://doi.org/10.32932/pjnh.2023.08.256

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