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au:Gomes, J.C.

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Microbiological growth analysis on a 275 kV transmission line composite insulator in South Africa
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Tshubwana, Rembuluwani P

; Gomes, Chandima

; van Coller, John

; Regnier, Thierry J.C.

South African Journal of Science

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feb 2024, Volume 120 N. 1-2 Pages 1 - 5

Abstract: En | Text: En | PDF: En

Transmission line silicon rubber insulators are frequently subjected to harsh environmental conditions that can change their surface characteristics and result in a transient or permanent loss of hydrophobicity. Algae, fungi, mould, and lichen are examples of biological growth that can compromise the power system's ability to operate safely by lowering the insulator's flashover voltage. We evaluated and identified the major microorganisms that could be responsible for the flashovers of insulators in South Africa. Due to the difficulty of accessing insulators currently in use within the electricity network, only two insulators, from two provinces in South Africa, were used in the study. Although algae were not found on the insulators, two major filamentous fungi identified as Curvularia sp. and Aspergillus sp. were isolated. The absence of algae could be attributed to the weather pattern of the two locations where the insulators were placed during their use as part of the network. According to previous studies worldwide, the high occurrence of these fungi could be linked to the reduction of flashover voltage of the composite insulators. Although a larger survey including more insulators from all provinces in South Africa should be conducted, the current study demonstrates the need for a cleaning programme for insulators using cost-effective eco-friendly antimicrobial agents. SIGNIFICANCE: • Degradation and loss of hydrophobicity on the overhead line composite due to biological growth were found to be an impediment to the safe operation of high-voltage insulators. Fungi were found to be the main factor causing the degradation of overhead transmission lines. • With these data, a model can be developed to predict the rate of biological growth on a given insulator, to estimate the degradation of the surface conditions with time for the utility to know when to remove them from the line. Such a model could lead to a more reliable and efficient power system and reduce the engineer's workload.

https://doi.org/10.17159/sajs.2024/15629

Regionalization of flow duration curves in the Amazon with the definition of homogeneous regions via fuzzy C-means
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PESSOA, FRANCISCO C.L.

; BLANCO, CLAUDIO J.C.

; GOMES, EVANICE P.

Anais da Academia Brasileira de Ciências

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2021, Volume 93 N. 1 elocation e20190747

Abstract: En | Text: En | PDF: En

Abstract Data insufficiency is one of the main challenges faced in hydrological studies, including a lack of knowledge regarding flow duration curves (FDCs). Thus, homogeneous regions of streamflow were identified in the Amazon using the Fuzzy C-Means (FCM) method. The PBM index was used to validate the clustering obtained via FCM, in turn, a homogeneity test based on the L-moment was applied to confirm the homogeneity in each defined region. Linear, power, exponential, logarithmic, quadratic and cubic mathematical models were fitted to the FDCs observed in the homogeneous regions. The models are the result of multiple regression analyses involving the parameters of the fitted FDC and the physico-climatic characteristics of the watersheds. The models were validated using the Jack-knife cross-validation method. The validation was satisfactory, with NASH coefficients higher than 0.50. Additionally, the standard deviation (RSR) of observations was less than 0.70, and the averages of the relative mean square error did not exceed 12.26%. These results are relevant for 89.91% of the analyzed watersheds and 73.58% of the study area. Thus, FDCs may be estimated in large parts of the Amazon, thereby making the methodology presented a valuable tool to support projects involving the planning and management of water resources.

https://doi.org/10.1590/0001-3765202120190747 249 downloads

Effects of vitamin D-induced supernatant of placental explants from preeclamptic women on oxidative stress and nitric oxide bioavailability in human umbilical vein endothelial cells
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Nunes, P.R.

; Gomes, V.J.

; Sandrim, V.C.

; Peraçoli, J.C.

; Peraçoli, M.T.S.

; Carlström, M.

Brazilian Journal of Medical and Biological Research

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2021, Volume 54 N. 8 elocation e11073

Abstract: En | Text: En | PDF: En

The study evaluated the effect of the supernatant of placental explants from preeclamptic (PE) and normotensive (NT) pregnant women after tissue treatment with or without vitamin D (VD) on oxidative stress and nitric oxide (NO) bioavailability in human umbilical vein endothelial cells (HUVEC). Placental explants were prepared from eight NT and eight PE women, and supernatants were obtained after incubation with or without hydrogen peroxide (H2O2) and/or VD. HUVEC were cultured for 24 h with supernatants, and the following parameters were analyzed in HUVEC cultures: NO, nitrate (NO3-), and nitrite (NO2-) levels, lipid peroxidation, and intracellular reactive oxygen species (ROS). Results showed that the production of NO3-, NO2-, malondialdehyde (MDA), and ROS were significantly higher in HUVEC treated with explant supernatant from PE compared to NT pregnant women, while the supernatant of PE explants treated with VD led to a decrease in these parameters. A significantly high production of NO was detected in HUVEC cultured with control supernatant of NT group, and in cultures treated with supernatant of PE explants treated with VD. Taken together, these results demonstrated that cultures of placental explants from PE women with VD treatment generated a supernatant that decreased oxidative stress and increased the bioavailability of NO in endothelial cells.

https://doi.org/10.1590/1414-431x2020e11073 229 downloads

Where do we aspire to publish? A position paper on scientific communication in biochemistry and molecular biology
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Baptista, M.S.

; Alves, M.J.M.

; Arantes, G.M.

; Armelin, H.A.

; Augusto, O.

; Baldini, R.L.

; Basseres, D.S.

; Bechara, E.J.H.

; Bruni-Cardoso, A.

; Chaimovich, H.

; Colepicolo Neto, P.

; Colli, W.

; Cuccovia, I.M.

; Da-Silva, A.M.

; Di Mascio, P.

; Farah, S.C.

; Ferreira, C.

; Forti, F.L.

; Giordano, R.J.

; Gomes, S.L.

; Gueiros Filho, F.J.

; Hoch, N.C.

; Hotta, C.T.

; Labriola, L.

; Lameu, C.

; Machini, M.T.

; Malnic, B.

; Marana, S.R.

; Medeiros, M.H.G.

; Meotti, F.C.

; Miyamoto, S.

; Oliveira, C.C.

; Souza-Pinto, N.C.

; Reis, E.M.

; Ronsein, G.E.

; Salinas, R.K.

; Schechtman, D.

; Schreier, S.

; Setubal, J.C.

; Sogayar, M.C.

; Souza, G.M.

; Terra, W.R.

; Truzzi, D.R.

; Ulrich, H.

; Verjovski-Almeida, S.

; Winck, F.V.

; Zingales, B.

; Kowaltowski, A.J.

Brazilian Journal of Medical and Biological Research

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2019, Volume 52 N. 9 elocation e8935

Abstract: En | Text: En | PDF: En

The scientific publication landscape is changing quickly, with an enormous increase in options and models. Articles can be published in a complex variety of journals that differ in their presentation format (online-only or in-print), editorial organizations that maintain them (commercial and/or society-based), editorial handling (academic or professional editors), editorial board composition (academic or professional), payment options to cover editorial costs (open access or pay-to-read), indexation, visibility, branding, and other aspects. Additionally, online submissions of non-revised versions of manuscripts prior to seeking publication in a peer-reviewed journal (a practice known as pre-printing) are a growing trend in biological sciences. In this changing landscape, researchers in biochemistry and molecular biology must re-think their priorities in terms of scientific output dissemination. The evaluation processes and institutional funding for scientific publications should also be revised accordingly. This article presents the results of discussions within the Department of Biochemistry, University of São Paulo, on this subject.

https://doi.org/10.1590/1414-431x20198935 1769 downloads

Antiedematogenic activity of the indole derivative N-salicyloyltryptamine in animal models
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SOUSA-NETO, BENEDITO P.

; GOMES, BRUNO S.

; CUNHA, FRANCISCO V.M.

; ARCANJO, DANIEL D.R.

; GUTIERREZ, STANLEY J.C.

; SOUZA, MARIA F.V.

; ALMEIDA, FERNANDA R.C.

; OLIVEIRA, FRANCISCO A.

Anais da Academia Brasileira de Ciências

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mar 2018, Volume 90 N. 1 Pages 185 - 194

Abstract: En | Text: En | PDF: En

ABSTRACT The N-salicyloyltryptamine (NST) is an indole derivative compound analogue to the alkaloid N-benzoyltryptamine. In the present study, the antiedematogenic activity of NST was investigated in animal models. Firstly, the acute toxicity for NST was assessed according to the OECD Guideline no. 423. The potential NST-induced antiedematogenic activity was evaluated by carrageenan-induced paw edema in rats, as well as by dextran-, compound 48/80-, histamine-, serotonin-, capsaicine-, and prostaglandin E2-induced paw edema in mice. The effect of NST on compound 48/80-induced ex vivo mast cell degranulation on mice mesenteric bed was investigated. No death or alteration of behavioral parameters was observed after administration of NST (2000 mg/kg, i.p.) during the observation time of 14 days. The NST (100 and 200 mg/kg, i.p.) inhibited the carrageenan-induced edema from the 1st to the 5th hour (**p<0.01; ***p<0.001). The edematogenic activity induced by dextran, compound 48/80, histamine, serotonin, capsaicin, and prostaglandin E2 was inhibited by NST (100 mg/kg, i.p.) throughout the observation period (**p<0.01; ***p<0.001). The pretreatment with NST (50, 100 or 200 mg/kg, i.p) attenuates the compound 48/80-induced mast cell degranulation (**p<0.01; ***p<0.001). Thus, the inhibition of both mast cell degranulation and release of endogenous mediators are probably involved in the NST-induced antiedematogenic effect.

https://doi.org/10.1590/0001-3765201720160502 1340 downloads

Morphometric analysis of feedforward pathways from the primary somatosensory area (S1) of rats
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Sá, A.L. de

; Bahia, C.P.

; Correa, V.C.

; Dias, I.A.

; Batista, C.

; Gomes-Leal, W.

; Pinho, A.L.S.

; Houzel, J.C.

; Picanço-Diniz, C.W.

; Pereira, A.

Brazilian Journal of Medical and Biological Research

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2016, Volume 49 N. 6 elocation e5115

Abstract: En | Text: En | PDF: En

We used biotinylated dextran amine (BDA) to anterogradely label individual axons projecting from primary somatosensory cortex (S1) to four different cortical areas in rats. A major goal was to determine whether axon terminals in these target areas shared morphometric similarities based on the shape of individual terminal arbors and the density of two bouton types: en passant (Bp) and terminaux (Bt). Evidence from tridimensional reconstructions of isolated axon terminal fragments (n=111) did support a degree of morphological heterogeneity establishing two broad groups of axon terminals. Morphological parameters associated with the complexity of terminal arbors and the proportion of beaded Bp vs stalked Bt were found to differ significantly in these two groups following a discriminant function statistical analysis across axon fragments. Interestingly, both groups occurred in all four target areas, possibly consistent with a commonality of presynaptic processing of tactile information. These findings lay the ground for additional work aiming to investigate synaptic function at the single bouton level and see how this might be associated with emerging properties in postsynaptic targets.

https://doi.org/10.1590/1414-431x20155115 1881 downloads

Reduction of blood nitric oxide levels is associated with clinical improvement of the chronic pelvic pain related to endometriosis
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Rocha, M.G.

; Gomes, V.A.

; Tanus-Santos, J.E.

; Rosa-e-Silva, J.C.

; Candido-dos-Reis, F.J.

; Nogueira, A.A.

; Poli-Neto, O.B.

Brazilian Journal of Medical and Biological Research

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apr 2015, Volume 48 N. 4 Pages 363 - 369

Abstract: En | Text: En | PDF: En

The objective of this prospective study was to determine the plasma levels of nitric oxide (NO) in women with chronic pelvic pain secondary to endometriosis (n=24) and abdominal myofascial pain syndrome (n=16). NO levels were measured in plasma collected before and 1 month after treatment. Pretreatment NO levels (μM) were lower in healthy volunteers (47.0±12.7) than in women with myofascial pain (64.2±5.0, P=0.01) or endometriosis (99.5±12.9, P<0.0001). After treatment, plasma NO levels were reduced only in the endometriosis group (99.5±12.9 vs 61.6±5.9, P=0.002). A correlation between reduction of pain intensity and reduction of NO level was observed in the endometriosis group [correlation = 0.67 (95%CI = 0.35 to 0.85), P<0.0001]. Reduction of NO levels was associated with an increase of pain threshold in this group [correlation = -0.53 (-0.78 to -0.14), P<0.0001]. NO levels appeared elevated in women with chronic pelvic pain diagnosed as secondary to endometriosis, and were directly associated with reduction in pain intensity and increase in pain threshold after treatment. Further studies are needed to investigate the role of NO in the pathophysiology of pain in women with endometriosis and its eventual association with central sensitization.

https://doi.org/10.1590/1414-431x20143619 2117 downloads

Níveis de farelo de coco em rações para leitões na fase de creche
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Carvalho, L.E.

; Watanabe, P.H.

; Ribeiro, J.C.

; Nepomuceno, R.C.

; Gomes, T.R.

; Oliveira, E.L.

Archivos de Zootecnia

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jun 2014, Volume 63 N. 242 Pages 295 - 303

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

A total of 32 male castrated boars and gilts of a commercial pig line aged 21 days and 6.20±0.92 kg of live weight were used to evaluate the performance and economical evaluation of copra meal inclusion in diets for piglets at nursery. Animals were allotted in a completely randomized block design with four treatments (0, 7, 14 and 21 % of copra meal), eight replicates per treatment and one animal as experimental unit. From 21 to 42 days of age, levels up to 7 % reduced daily weight gain of piglets (p<0.05). A quadratic trend on feed:gain ratio was observed from 42 to 63 days and total period (p<0.05), with better results at estimated level of 14.33 and 13.99 %, respectively. No effect of copra meal inclusion on economical variables was observed from 21 to 42 days of age. From 43 to 63 days and total period (21 to 63 days) a quadratic effect on economical indexes was observed with the inclusion of different levels of copra meal, with better results around 15 %. The inclusion of copra meal until the level of 7 % is recommended in piglet diets from 21 to 42 days of age. From 43 to 63 days, the estimated level of 15 % results in better performance and economical indexes. It is recommended to include up to 7 % of coconut meal in diets for pigs from 21 to 42 days old. From 43 to 63 days of age, the estimated level of 15 % resulted in better performance.

Utilizou-se 32 leitões machos castrados e fêmeas de linhagem comercial, desmamados com 21 dias de idade e peso vivo médio de 6,20±0,92 kg, objetivando avaliar o desempenho e a avaliação econômica de níveis inclusão de farelo de coco (FC) em rações para leitões na fase de creche. Os animais foram distribuídos em um delineamento em blocos ao acaso, com quatro tratamentos (0, 7, 14 e 21 % de farelo de coco), oito repetições por tratamento e um animal por unidade experimental. Observou-se que dos 21 aos 42 dias de idade, a inclusão de níveis acima de 7 % de farelo de coco na ração resultou em efeito linear negativo (p<0,05) sobre o ganho de peso diário. Dos 43 aos 63 dias de idade e no período total (21 a 63 dias de idade), observou-se feito quadrático dos níveis de FC nas rações (p<0,05) sobre a conversão alimentar, estimando-se melhor nível de 14,33 e 13,99 %, respectivamente. Para a fase dos 21 a 42 dias de idade, não houve efeito da inclusão de farelo de coco sobre as variáveis econômicas avaliadas. No entanto, dos 43 aos 63 dias e no período total (21 a 63 dias), observou-se efeito quadrático para as variáveis econômicas em função dos níveis de farelo de coco nas rações (p<0,05), com melhores resultados ao nível estimado aproximado de 15 %. Recomenda-se a inclusão de até 7 % de farelo de coco em rações para leitões dos 21 aos 42 dias de idade. Para a fase posterior, dos 43 a 63 dias de idade, o nível estimado de 15 % resultou em melhores índices de desempenho e econômico. Recomenda-se a inclusão de até 7 % de farelo de coco em rações para leitões dos 21 a 42 dias de idade. Para a fase posterior, dos 43 aos 63 dias de idade, o nível estimado de 15 % resultou em melhores índices de desempenho.

https://doi.org/10.4321/S0004-05922014000200008 880 downloads

Stability and adaptability analysis of Tabapuã bulls for performance traits according to the herd level
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Marçal, M.F.

; Ferraz Filho, P.B.

; Souza, J.C.

; Silva, L.O.C.

; Gomes, F.J.

; Freitas, J.A.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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feb 2014, Volume 66 N. 1 Pages 195 - 202

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Com o objetivo de estudar a estabilidade e a adaptabilidade de bovinos da raça Tabapuã para a característica peso aos 120 dias efeito materno, empregou-se metodologias de regressão linear. As análises incluíram as diferenças esperadas nas progênies de cinco reprodutores em quatro rebanhos, localizados nos estados da Bahia (rebanhos 1 e 2), Paraná (rebanho 3) e Minas Gerais (rebanho 4). Os resultados mostraram que o desempenho dos touros depende, em grande parte, da variabilidade genética das matrizes para a característica estudada nos diferentes rebanhos, o que permite a recomendação de reprodutores específicos para cada rebanho. As análises de adaptabilidade e estabilidade discriminaram diferenças de desempenho nos rebanhos e identificaram touros perfeitamente adaptados e estáveis, touros com adaptação geral, com adaptação específica a ambientes favoráveis e desfavoráveis.

In order to study the stability and adaptability of Tabapuã cattle for the characteristic weight at 120 days of maternal effect, we used methods based on linear regression. The analysis included differences in the expected progeny of five sire sin herds located in four farms in the states of Bahia, (herds 1and 2), Paraná (herd 3) and Minas Gerais (herd 4). The results show that the performance of bulls depend largely on the genetic variability of the matrices for different characteristics in herds studied, allowing the recommendation of a specific breeding herd. Analyses of adaptability and stability discriminated performance differences in herds. Bulls were identified as adapted and perfectly stable, bulls with general adaptation, and with specific adaptation to favorable and unfavorable environments.

1657 downloads

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Degradabilidade in situ do bagaço de cana-de-açúcar para pequenos ruminantes de raças naturalizadas do Nordeste brasileiro
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Gomes, G.M.F.

; Vasconcelos, A.M.

; Egito, A.S.

; Lima, A.R.

; Carneiro, J.C.

; Landim, A.V.

; Fonteles, N.L.O.

; Salles, H.O.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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dec 2013, Volume 65 N. 6 Pages 1792 - 1800

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Com o crescimento da indústria sucroalcooleira, buscam-se alternativas de uso dos resíduos gerados por ela. Os pequenos ruminantes de raças naturalizadas do Nordeste brasileiro mostram-se como grupos potenciais para que seja utilizado o bagaço de cana-de-açúcar (BCA) nas dietas. Nesse contexto, objetivou-se determinar a degradabilidade ruminal in situ da matéria seca (MS) e da fibra em detergente neutro (FDN) do BCA e os parâmetros ruminais em caprinos Moxotó e ovinos Morada Nova, fistulados no rúmen. Contidos em sacos de náilon, 3g de BCA foram incubados no rúmen nos tempos seis, 24 e 96 horas, determinando-se o conteúdo de MS e FDN nos resíduos obtidos. Nos tempos zero, seis e 12 horas após a primeira refeição, mediram-se no líquido ruminal pH e nitrogênio amoniacal (N-NH3) ruminal. O CMS não diferiu entre caprinos e ovinos. O potencial de máxima degradação da MS foi semelhante entre espécies, e da FDN foi superior em caprinos. Ovinos apresentaram maiores tempo de colonização, taxa de degradação e degradabilidade efetiva da MS e FDN. O pH não diferiu entre as espécies. Observou-se maior concentração de N-NH3 ruminal em caprinos, no tempo zero. Diante da maior velocidade de degradação da MS do BCA pelos ovinos, essa espécie se mostra detentora de uma microbiota ruminal com crescimento mais eficiente sobre o BCA.

With the increase of the sugar and alcohol industries, alternative uses for residue are sought, and the small ruminants from the naturalized breeds of northeastern Brazil are potential groups to make use of the sugarcane bagasse (SCB) in their diets. In this context, the objective was to determine the in situ degradability of dry matter (DM) and neutral detergent fiber (NDF) of SCB and ruminal parameters in Moxotó goats and Morada Nova sheep rumen fistulated. Three grams of SCB were placed in naylon bags and incubated in the rumen at 6, 24 and 96 hours, and the residues analyzed for DM and NDF. Rumen fluid was collected at zero, 6 and 12 hours after the first meal and pH and ammonia nitrogen (N-NH3) were determined. DMI did not differ between goats and sheep. The maximum degradation potential of DM was similar between species and the A of NDF was higher in goats. Sheep had higher colonization time, rate of degradation and effective degradability of DM and NDF. The pH did not differ between species. The highest concentration of ruminal N-NH3in goats was at time zero. Given the higher rate of degradation of bagasse dry matter by sheep, this specie shows a more efficient rumen microbial growth on SCB.

2192 downloads

11.

Production of L1 protein from different types of HPV in Pichia pastoris using an integrative vector
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Coimbra, E.C.

; Gomes, F.B.

; Campos, J.F.

; D’arc, M.

; Carvalho, J.C.

; Mariz, F.C.

; Jesus, A.L.S.

; Stocco, R.C.

; Beçak, W.

; Freitas, A.C.

Brazilian Journal of Medical and Biological Research

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dec 2011, Volume 44 N. 12 Pages 1209 - 1214

Abstract: En | Text: En | PDF: En

Human papillomavirus (HPV) infection is the most common sexually transmitted disease in the world and is related to the etiology of cervical cancer. The most common high-risk HPV types are 16 and 18; however, the second most prevalent type in the Midwestern region of Brazil is HPV-33. New vaccine strategies against HPV have shown that virus-like particles (VLP) of the major capsid protein (L1) induce efficient production of antibodies, which confer protection against the same viral type. The methylotrophic yeast Pichia pastoris is an efficient and inexpensive expression system for the production of high levels of heterologous proteins stably using a wild-type gene in combination with an integrative vector. It was recently demonstrated that P. pastoris can produce the HPV-16 L1 protein by using an episomal vector associated with the optimized L1 gene. However, the use of an episomal vector is not appropriate for protein production on an industrial scale. In the present study, the vectors were integrated into the Pichia genome and the results were positive for L1 gene transcription and protein production, both intracellularly and in the extracellular environment. Despite the great potential for expression by the P. pastoris system, our results suggest a low yield of L1 recombinant protein, which, however, does not make this system unworkable. The achievement of stable clones containing the expression cassettes integrated in the genome may permit optimizations that could enable the establishment of a platform for the production of VLP-based vaccines.

6398 downloads Cited 1 time in SciELO

12.

Qualidade de méis produzidos por apicultores e méis provenientes de entrepostos registrados no Serviço de Inspeção Federal
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Silva, M.B.L.

; Chaves, J.B.P.

; Valente, M.E.R.

; Gomes, J.C.

; Oliveira, G.F.

; Message, D.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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aug 2011, Volume 63 N. 4 Pages 1043 - 1045

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

This study was carried out to compare the physiochemical quality of honeys from beekeepers in northern Zona da Mata, MG, and honeys from warehouses registered at the Serviço de Inspeção Federal (SIF) in the State of Minas Gerais. Physiochemical analysis involving 39 samples were done, with three samples from each of the 13 beekeepers and 18 samples from warehouses registered at SIF-MG. Differences in quality from the two origins occurred in: free acidity, ashes, hydroxymethylfurfural, apparent sucrose and insoluble solids, where honeys from warehouses were of better quality. In addition, for free acidity and insoluble solids, two samples from northern Zona da Mata showed values above the established by the Instrução Normativa n°11 relative to the year 2000, whereas the values for insoluble solids in 11 samples from northern Zona da Mata and 2 samples from warehouses were in disagreement with this legislation.

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13.

Punción venosa pediátrica: Un análisis crítico a partir de la experiencia del cuidar en enfermería
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De Oliveira Gomes, A.V.

; De Luca Nascimento, M.A.

; Moreira Christoffel, M.

; Pereira Antunes, J.C.

; Campos de Araújo, M.

; Gomes Cardim, M.

Enfermería Global

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jul 2011, Volume 10 N. 23 Pages 277 - 286

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

It is a descriptive observational study made from the authors' observations in their respective works which aims to: a) Describe the signs seen in children submitted to repeated punctures in peripheral venous b) Emphasize, in the light of the literature found, the importance of clinical evaluation of the nurse to establish a plan of care for the child. Starting from the daily practice of caring, the signs located in the emotional, ohysical and psychological areas which according to the literature may generate feelings of fear and anxiety, and which may interfere in the growth process and child development were described in relation to children submitted to multiple punctures in peripheral venous. We concluded that the clinical evaluation of the nurse is very important because, the effects of multiple punctures in peripheral venous of the children can be prevented by early identification of the nursing diagnosis and implementation of a plan of care appropriate to this clientele.

Estudo descritivo observacional realizado a partir da observação das autoras em seus respectivos ambientes de trabalho, que tem como objetivos: a) Descrever os sinais observados na criança submetida às repetidas punções venosas periféricas e; b) Enfatizar, à luz da bibliografia consultada, a importância da avaliação clínica do enfermeiro para estabelecer um plano de cuidados a essa criança. A partir do cotidiano da prática de cuidar foram descritos, em relação às crianças submetidas às múltiplas punções venosas periféricas, sinais alocados nas áreas emocional, física e fisiológica que, segundo a bibliografia consultada, podem gerar sentimentos de medo e ansiedade, que interferem no processo do crescimento e desenvolvimento infantil. Conclui-se que, a avaliação clínica do enfermeiro é de vital importância, porque, a partir dela, os efeitos das múltiplas punções venosas periféricas em pediatria podem ser evitadas mediante a identificação precoce do diagnóstico de enfermagem e a implementação de um plano de cuidados adequado a essa clientela.

Estudio descriptivo observacional realizado a partir de la observación de las autoras en sus respectivos ámbitos de trabajo, que tiene por objeto: a) describir los signos observados en los niños sometidos a repetidas punciones venosas periféricas y b) hacer hincapié, a la luz de la literatura consultada, en la importancia de la evaluación clínica de la enfermera para establecer un plan de cuidado para el niño. Desde el cotidiano de la práctica del cuidar se describen, referido a los niños objeto de múltiples punciones venosas periféricas, los signos ubicados en las áreas emocional, física y fisiológica que, según la bibliografía consultada, puede generar sentimientos de miedo y ansiedad, que interfieren en el proceso de crecimiento y desarrollo del niño. Se concluyó que la evaluación clínica de la enfermera es de vital importancia, ya que, a partir de ella, los efectos de las múltiples punciones venosas periféricas en pediatría pueden prevenirse mediante la identificación temprana de los diagnósticos de enfermería y la aplicación de un plan de cuidados adecuados a esta clientela.

https://doi.org/10.4321/S1695-61412011000300019 6241 downloads

14.

Cinzas volantes álcali-ativadas com solução combinada de NaOH e Ca(OH)2
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Vargas, A.S.

; Dal Molin, D.C.C.

; Vilela, A.C.F.

; Jalali, S.

; Gomes, J.C.

Matéria (Rio de Janeiro)

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2007, Volume 12 N. 3 Pages 462 - 469

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Este trabalho teve como objetivo avaliar o comportamento da resistência à compressão, ao longo do tempo, em amostras de argamassas à base de cinzas volantes álcali-ativadas. Como ativador alcalino foi utilizada uma solução combinada de NaOH e Ca(OH)2. A cura das amostras foi realizada de duas formas distintas. Na primeira, as amostras foram mantidas em estufa à 70°C/12 h e à temperatura constante de 22°C em sala climatizada até a idade de ensaio. Apesar de serem obtidas resistências da ordem de 20 MPa nas primeiras 24 h, houve decréscimo da resistência a partir da idade de 7 dias. Verificado esse comportamento, um segundo método de cura foi adotado. Para isso, o traço utilizado para o preparo de novas argamassas foi o mesmo adotado no método anterior. Porém, foram submetidas à temperatura constante de 70°C até a idade de ensaio. Nesse caso, as amostras apresentaram decréscimo mais acentuado da resistência em menor espaço de tempo, quando comparado às amostras curadas no primeiro método. Como estudos complementares foram realizadas análises microestruturais da CV antes e depois da álcali-ativação, utilizando o MEV/EDS. Nas imagens microestruturais foi possível identificar três morfologias distintas nas pastas álcali-ativadas: uma composta de regiões com aspecto denso; outra apresentando partículas de cinzas volantes parcialmente solubilizadas; e outra mostrando a formação de produtos em forma de cristais aciculares. Porém, apenas o uso do MEV/EDS não foi suficiente para que se pudesse entender o mecanismo de reação deletéria provocada entre os ativadores alcalinos e a cinza volante. Portanto, trabalhos futuros deverão contemplar o uso de ferramentas auxiliares às adotadas nesse trabalho com o objetivo de esclarecer tal mecanismo deletério.

The main objective of this work was to evaluate over time the development of the compressive strength of alkali-activated fly ash mortars. A combined solution of NaOH and Ca(OH)2 was used as alkaline activator. The curing of the samples was carried out in two distinct ways. In the first one, samples were kept at 70°C during the first 12 hours after mixing and at 22°C afterwards, until the age of testing. Although compressive strengths of about 20 MPa were achieved during the first 24 hours, the strength started to decrease after 7 days. Considering this behaviour, a second method of curing was adopted. The mix proportions were the same as before, however the mortar samples were kept in an oven at 70°C until the age of testing. In this case, the compressive strength values decreased more significantly and in a shorter period of time, as compared to the results obtained for samples cured using the first method. Complementary studies were performed in order to better understand the observed reduction in compressive strength. Microstructural analyses of the fly ash, before and after the alkali-activation, have been carried out using Scanning Electron Microscopy (SEM) and Energy-Dispersive Spectroscopy (EDS). It was possible to identify three different morphologies in the alkali-activated pastes: one composed by regions with dense aspect; other showing partially solubilised particles of fly ash; and a third showing the formation of products with a needle-like shape. The information provided by the SEM/EDS experiments was not enough to enable the complete understanding of the mechanism of the deleterious reaction that took place among the alkaline activators and the fly ash. Therefore, future studies should address this question by using additional analysis tools in order to clarify this deleterious mechanism.

3318 downloads Cited 2 times in SciELO

15.

<a name="home"></a>Lycopene and ß-carotene protect in vivo iron-induced oxidative stress damage in rat prostate
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Matos, H.R.

; Marques, S.A.

; Gomes, O.F.

; Silva, A.A.

; Heimann, J.C.

; Di Mascio, P.

; Medeiros, M.H.G.

Brazilian Journal of Medical and Biological Research

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feb 2006, Volume 39 N. 2 Pages 203 - 210

Abstract: En | Text: En | PDF: En

It has been suggested that iron overload may be carcinogenic. In the present study, we evaluated the effect of plasma and prostate carotenoid concentration on oxidative DNA damage in 12-week-old Wistar rats treated with intraperitoneal (ip) ferric nitrilotriacetate (Fe-NTA) (10 mg Fe/kg). Plasma ß-carotene and lycopene concentrations were measured as a function of time after ip injection of carotenoids (10 mg kg-1 day-1 ß-carotene or lycopene) in rats. The highest total plasma concentration was reached 3 and 6 h after ip injection of lycopene or ß-carotene, respectively. After 5 days of carotenoid treatment, lycopene and ß-carotene were present in the 0.10-0.51 nmol/g wet tissue range in the prostate. Using a sensitive method to detected 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) by HPLC/EC, the level of 8-oxodGuo in rat prostate DNA was significantly higher (6.3 ± 0.6 residues/10(6) dGuo) 3 h after Fe-NTA injection compared with control rats (1.7 ± 0.3 residues/10(6) dGuo). Rats supplemented with lycopene or ß-carotene for 5 days prior to Fe-NTA treatment showed a reduction of about 70% in 8-oxodGuo levels to almost control levels. Compared with control rats, the prostate of Fe-NTA-treated animals showed a 78% increase in malondialdehyde accumulation. Lycopene or ß-carotene pre-treatment almost completely prevented lipid damage. Epidemiological studies have suggested a lower risk of prostate cancer in men reporting a higher consumption of tomato products. However, before associating this effect with tomato sauce constituents, more information is required. The results described here may contribute to the understanding of the protective effects of carotenoids against iron-induced oxidative stress.

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