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RESUMO OBJETIVO Estimar a soroprevalência de anticorpos do vírus SARS-CoV-2 em escolares de quatro a 14 anos de idade residentes no município de São Paulo, segundo variáveis clínicas, demográficas, epidemiológicas e sociais, durante o período de fechamento das escolas como medida de controle da covid-19. MÉTODOS Realizou-se um inquérito sorológico em setembro de 2020 com amostra aleatória estratificada por tipo de rede de ensino (pública municipal, pública estadual e privada). Foi coletada amostra de sangue venoso utilizando-se o teste de imunoensaio de fluxo lateral da fabricante Wondfo para detecção de anticorpos totais contra o vírus SARS-CoV-2. Aplicaram-se questionários semiestruturados para o levantamento de dados clínicos, demográficos, sociais e epidemiológicos. RESULTADOS A soroprevalência de anticorpos do vírus SARS-CoV-2 em escolares foi de 16,6% (IC95% 15,4–17,8). O estudo encontrou soroprevalências mais elevadas na rede pública municipal (18,5%; IC95% 16,6–20,6) e estadual (16,2%; IC95% 14,4–18,2) em relação à rede privada (11,7; IC95% 10,0–13,7) e entre escolares da raça/cor preta e parda (18,4%; IC95% 16,8–20,2) e no estrato social mais vulnerável (18,5%; IC95% 16,9–20,2). A pesquisa identificou menores soroprevalências nos escolares que relataram seguir as medidas recomendadas de proteção contra a covid-19. CONCLUSÃO A soroprevalência de anticorpos contra o vírus SARS-CoV-2 atinge principalmente os escolares socialmente mais vulneráveis. Este estudo pode contribuir para embasar políticas públicas que reforcem a importância da suspensão das aulas presenciais e da necessidade de estratégias de medidas de proteção e acompanhamento do status sorológico daqueles que ainda não foram contemplados no calendário vacinal.

ABSTRACT OBJECTIVE To estimate seroprevalence of SARS-CoV-2 antibodies in schoolchildren aged 4 to 14 years living in the city of São Paulo, according to clinical, demographic, epidemiological, and social variables, during the school closure period as a measure against covid-19 spread. METHODS A serological survey was made in September 2020 with a random sample stratified by school system (municipal public, state public and private) type. A venous blood sample was collected using the Wondfo SARS-CoV-2 Antibody Test (lateral flow method) for detection of total SARS-CoV-2 virus antibodies. Semi-structured questionnaires were applied to collect clinical, demographic, social, and epidemiological data. RESULTS Seroprevalence of SARS-CoV-2 antibodies in schoolchildren was of 16.6% (95%CI 15.4–17.8). The study found higher seroprevalence in the municipal (18.5%; 95%CI 16.6–20.6) and state (16.2%; 95%CI 14.4–18.2) public school systems compared to the private school system (11.7; 95%CI 10.0–13.7), among black and brown students (18.4%; 95%CI 16.8–20.2) and in the most vulnerable social stratum (18.5 %;95%CI 16.9–20.2). Lower seroprevalence was identified in schoolchildren who reported following the recommended protective measures against covid-19. CONCLUSION Seroprevalence of SARS-CoV-2 antibodies is found mainly in the most socially vulnerable schoolchildren. This study can contribute to support public policies that reinforce the importance of suspending face-to-face classes and developing strategies aimed at protective measures and monitoring of the serological status of those who have not yet been included in the vaccination schedule.

https://doi.org/10.11606/s1518-8787.2023057004782

Seroprevalence of SARS-CoV-2 antibodies in schoolchildren in the city of São Paulo, 2020
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Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Albuquerque, José Olimpio Moura de

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Sato, Ana Paula Sayuri

; Glasser, Paula Regina

; Pino, Francisco Alberto

; Burihan, Patrícia Carla Piragibe Ramos

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Cavazzana, Cinthya Luzia

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Caldeira, Luiz Artur Vieira

; Silva, Solange Maria Saboia e

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Mauro, Athenê Maria de Marco França

; Masi, Eduardo de

Revista de Saúde Pública

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2023, Volume 57 elocation 6s

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.11606/s1518-8787.2023057004782

Prevalence of characteristics associated with sarcopenia in elders: a cross-sectional study
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Sousa, Caroline Ribeiro de

; Coutinho, Janaína Fonseca Victor

; Marques, Marília Braga

; Barbosa, Rachel Gabriel Bastos

; Roriz Filho, Jarbas de Sá

; Soares, Edson Silva

; Nogueira, Charlys Barbosa

; Souza, Rodrigo Lopes de Paula

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 2 elocation e20220209

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: identificar a prevalência e as características associadas à sarcopenia em pessoas idosas de Unidades de Atenção Primária à Saúde. Métodos: estudo transversal, com 384 pessoas idosas. Para avaliação de sarcopenia, mediu-se: força e massa muscular, desempenho físico. Classificaram se pessoas idosas com: sarcopenia provável; sarcopenia; e sarcopenia grave. Analisou-se com teste de qui quadrado e método de regressão logística multinomial. Resultados: a prevalência de provável sarcopenia foi de 25,52%; sarcopenia, 11,98%; e sarcopenia grave, 9,90%. Homens são 1,75 vez mais prevalentes em indivíduos com provável sarcopenia; osteoporose é 2,16 vezes mais prevalente na sarcopenia grave; polifarmácia, 1,57 vez mais prevalente na provável sarcopenia; circunferência da panturrilha menor que 31 cm é 2,24 vezes mais prevalente na sarcopenia e 2,19 vezes na sarcopenia grave. Conclusões: houve maior prevalência de provável sarcopenia, e as características associadas à sarcopenia foram: sexo, osteoporose, polifarmácia, sobrepeso, obesidade e circunferência da panturrilha.

ABSTRACT Objectives: to identify the prevalence and characteristics associated with sarcopenia in elders in Primary Health Care Units. Methods: cross-sectional study with 384 elders. To evaluate sarcopenia, we measured: strength and muscle mass, and physical performance. The elderly were classified as having: probable sarcopenia; sarcopenia; or severe sarcopenia. The chi-squared test and the multinomial logistic regression method were used. Results: the prevalence of probable sarcopenia was 25.52%; of sarcopenia, 11.98%; and of severe sarcopenia, 9.90%. Probable sarcopenia is 1.75 times more prevalent in men; osteoporosis is 2.16 times more prevalent in people with severe sarcopenia; polypharmacy is 1.57 times more likely in individuals with probable sarcopenia; and calf circumference below 31 cm is 2.24 times more likely in patients with sarcopenia and 2.19 times more likely in patients with severe sarcopenia. Conclusions: the highest prevalence was of probable sarcopenia, and the characteristics associated with sarcopenia were sex, osteoporosis, polypharmacy, overweight, obesity, and calf circumference.

RESUMEN Objetivos: identificar prevalencia y características relacionadas a la sarcopenia en personas ancianas de Unidades de Atención Primaria de Salud. Métodos: estudio transversal, con 384 personas ancianas. Para evaluación de sarcopenia, medidos: fuerza y masa muscular, desempeño físico. Clasificadas personas ancianas con: sarcopenia probable; sarcopenia; y sarcopenia grave. Analizado con prueba chi cuadrado y método de regresión logística multinomial. Resultados: la prevalencia de probable sarcopenia fue de 25,52%; sarcopenia, 11,98%; y sarcopenia grave, 9,90%. Hombres son 1,75 vez más prevalentes en individuos con probable sarcopenia; osteoporosis es 2,16 veces más prevalente en la sarcopenia grave; polifarmacia, 1,57 vez más prevalente en la probable sarcopenia; circunferencia de los gemelos menor que 31 cm es 2,24 veces más prevalente en la sarcopenia y 2,19 veces en la sarcopenia grave. Conclusiones: Hubo mayor prevalencia de probable sarcopenia, y las características relacionadas a la sarcopenia fueron: sexo, osteoporosis, polifarmacia, sobrepeso, obesidad y circunferencia de los gemelos.

https://doi.org/10.1590/0034-7167-2022-0209

Estratégia Fármaco-Invasiva no Infarto do Miocárdio: Análise Descritiva, Apresentação de Sintomas Isquêmicos e Preditores de Mortalidade
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Bianco, Henrique Tria

; Povoa, Rui

; Izar, Maria Cristina

; Alves, Claudia Maria Rodrigues

; Barbosa, Adriano Henrique Pereira

; Bombig, Maria Teresa Nogueira

; Gonçalves Jr, Iran

; Luna Filho, Bráulio

; Aguirre, Ana Caroline

; Moraes, Pedro Ivo de Marqui

; Almeida, Dirceu

; Moreira, Flávio Tocci

; Povoa, Fernando Focaccia

; Stefanini, Edson

; Caixeta, Adriano Mendes

; Bacchin, Amanda S.

; Moisés, Valdir Ambrósio

; Fonseca, Francisco A.H.

Arquivos Brasileiros de Cardiologia

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nov 2022, Volume 119 N. 5 Pages 691 - 702

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento O infarto do miocárdio com elevação do segmento-ST (IAMCSST) é definido por sintomas acompanhados por alterações típicas do eletrocardiograma. Entretanto, a caracterização dos sintomas isquêmicos não é clara, principalmente em subgrupos, como mulheres e idosos. Objetivos Analisar a tipificação dos sintomas isquêmicos, métricas temporais e observar a ocorrência de desfechos intra-hospitalares, em análise dos escores preditivos, em pacientes com IAMCSST, em estratégia fármaco-invasiva. Métodos Estudo envolvendo 2.290 pacientes. Tipos de apresentações clínicas pré-definidas: dor típica, dor atípica, dispnéia, sincope. Medimos o tempo entre o início dos sintomas à demanda pelo atendimento e o intervalo entre a chegada à unidade-médica e trombólise. Odds-ratios (OR; IC-95%) foram estimadas em modelo de regressão. Curvas ROCs foram construídas para preditores de mortalidade. Nível de significância adotado (alfa) foi de 5%. Resultados Mulheres apresentaram alta prevalência de sintomas atípicos; maior tempo entre o início dos sintomas e a procura por atendimento; atraso entre a chegada ao pronto-socorro e a fibrinólise. A mortalidade hospitalar foi de 5,6%. Predição de risco pela classificação Killip-Kimball: AUC: [0,77 (0,73-0,81)] em classe ≥II. Subgrupos estudados [OR (IC-95%)]: mulheres [2,06 (1,42-2,99); p=0,01]; insuficiência renal crônica [3,39 (2,13-5,42); p<0,001]; idosos [2,09 (1,37-3,19) p<0,001]; diabéticos [1,55 (1,04-2,29); p=0,02]; obesos 1,56 [(1,01-2,40); p=0,04]; acidente vascular cerebral prévio [2,01 (1,02-3,96); p=0,04] correlacionaram-se com maiores taxas de mortalidade. Conclusão Apesar das mais altas taxas de mortalidade em alguns subgrupos, disparidade significativa persiste nas mulheres, com atrasos no reconhecimento dos sintomas e trombólise imediata. Destaca-se a aplicabilidade do escore Killip-Kimball na predição, independentemente da apresentação clínica.

Abstract Background ST-segment elevation myocardial infarction (STEMI) is defined by symptoms accompanied by typical electrocardiogram changes. However, the characterization of ischemic symptoms is unclear, especially in subgroups such as women and the elderly. Objectives To analyze the typification of ischemic symptoms, temporal metrics and observe the occurrence of in-hospital outcomes, in the analysis of predictive scores, in patients with STEMI, in a drug-invasive strategy. Methods Study involving 2,290 patients. Types of predefined clinical presentations: typical pain, atypical pain, dyspnea, syncope. We measured the time between the onset of symptoms and demand for care and the interval between arrival at the medical unit and thrombolysis. Odds-ratios (OR; CI-95%) were estimated in a regression model. ROC curves were constructed for mortality predictors. The adopted significance level (alpha) was 5%. Results Women had a high prevalence of atypical symptoms; longer time between the onset of symptoms and seeking care; delay between arrival at the emergency room and fibrinolysis. Hospital mortality was 5.6%. Risk prediction by Killip-Kimball classification: AUC: [0.77 (0.73-0.81)] in class ≥II. Subgroups studied [OR (CI-95%)]: women [2.06 (1.42-2.99); p=0.01]; chronic renal failure [3.39 (2.13-5.42); p<0.001]; elderly [2.09 (1.37-3.19) p<0.001]; diabetics [1.55 (1.04-2.29); p=0.02]; obese 1.56 [(1.01-2.40); p=0.04]: previous stroke [2.01 (1.02-3.96); p=0.04] correlated with higher mortality rates. Conclusion Despite higher mortality rates in some subgroups, significant disparity persists in women, with delays in symptom recognition and prompt thrombolysis. We highlight the applicability of the Killip-Kimball score in prediction, regardless of the clinical presentation.

https://doi.org/10.36660/abc.20211055

The effect of socioeconomic aspects and dental history on pediatric patients’ dental anxiety
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AMORIM, Camila Silva de

; MENEZES, Bruna Silva de

; CHAVES, Janaina Nascimento Teixeira

; PEREIRA JUNIOR, Edson Paiva

; COQUEIRO, Raildo da Silva

; FONSECA-GONÇALVES, Andréa

; MAIA, Lucianne Cople

; PITHON, Matheus Melo

Brazilian Oral Research

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2022, Volume 36 elocation e106

Abstract: En | Text: En | PDF: En

Abstract This study aimed to characterize the profile of dental anxiety in pediatric patients, identifying the effect exerted by socioeconomic factors using dental data. A cross-sectional study design with a sample of 120 children aged 7–12 years old was used. Data relating to anxiety levels prior to dental care, socioeconomic aspects (family income, education level, child’s school type), and child’s dental history (previous dental appointments, previous treatment, caries experience) were collected. Additionally, participants completed the Brazilian version of the Children’s Fear Survey Schedule- Dental Subscale (B-CFSS-DS) to assess dental anxiety. Descriptive analyses, chi-squared (X 2 ) tests, and Mann-Whitney U tests were performed, with a significance level of 5%. A total of 51 boys (42.5%) and 69 girls (57.5%) were included. There was no significant difference in dental anxiety between them. However, younger children had higher mean B-CFSS-DS scores (p = 0.036, Mann-Whitney). A higher prevalence of dental anxiety was found in participants from low-income families (p = 0.012, X 2 ) and in patients who did not receive endodontic treatment (p=0.034, X 2 ). Higher mean B-CFSS-DS scores were also observed in participants who did not receive endodontic treatment (p=0.001, Mann-Whitney) compared with those that did receive endodontic treatment. No relationship was found between education level, patient school type, first dental appointment, caries experience, and dental anxiety data. Younger children presented a profile of greater dental anxiety. Socioeconomic factors and dental data exerted some effect on dental anxiety, where children from low-income families and those not subjected to endodontic treatment displayed higher rates of dental anxiety.

https://doi.org/10.1590/1807-3107bor-2022.vol36.0106

Genetic parameters for growth, reproductive, and carcass traits in Tabapuã cattle
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Freitas, Thais Correia

; Ventura, Henrique Torres

; Silva, Fabyano Fonseca e

; Veroneze, Renata

; Costa, Edson Vinicius

; Silva, Delvan Alves da

; Marques, Daniele Botelho Diniz

; Lopes, Paulo Sávio

Revista Brasileira de Zootecnia

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2022, Volume 51 elocation e20210188

Abstract: En | Text: En | PDF: En

ABSTRACT We aimed to estimate genetic parameters for growth, reproductive, and carcass traits in Tabapuã cattle. Phenotypic data were collected between 1990 and 2019 in 1,218 farms, and the pedigree file had 340,868 animals. The traits evaluated were body weight at 120 (W120), 210 (W210), 365 (W365), and 550 (W550) days of age; age at first calving (AFC), scrotal circumference at 365 days of age (SC365), ribeye area (REA), backfat thickness (BF), and rump fat thickness (RF). The (co)variance components were estimated using the restricted maximum likelihood method, considering single and two-traits animal models. For all traits, the models considered fixed, direct additive genetic, and residual random effects. In addition, for W120 and W210, the maternal additive genetic and maternal permanent environmental effects were also included. Heritabilities for W120, W210, W365, W550, SC365, REA, BF, and RF were of moderate magnitude (0.15, 0.16, 0.23, 0.19, 0.22, 0.36, 0.31, and 0.27, respectively). Low heritability was observed for AFC (0.07). The genetic correlations between growth traits were higher than 0.90, while AFC and SC365 presented negative moderate correlation (−0.66). The REA showed low genetic correlations with BF (0.07) and RF (0.07), whereas BF and RF were highly correlated (0.77). Considering the heritability estimates, selection for AFC would result in limited genetic gain, while for the other traits, it would be satisfactory. Based on the high genetic correlations between growth traits, selection of Tabapuã animals can be performed at younger ages. Additionally, animals can be indirectly selected for AFC through SC365, and only one fat thickness trait may be used in the selection process considering the high genetic correlation and similar heritability values for BF and RF.

https://doi.org/10.37496/rbz5120210188

Acurácia da Redução do Segmento-ST Pós-Trombólise como Preditor de Reperfusão Adequada em Estratégia Fármaco-Invasiva
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Bianco, Henrique Tria

; Povoa, Rui

; Izar, Maria Cristina

; Luna Filho, Braulio

; Moreira, Flavio Tocci

; Stefanini, Edson

; Fonseca, Henrique Andrade

; Barbosa, Adriano Henrique Pereira

; Alves, Claudia Maria Rodrigues

; Caixeta, Adriano Mendes

; Gonçalves Jr, Iran

; Moraes, Pedro Ivo de Marqui

; Lopes, Renato Delascio

; Paola, Angelo Amato Vincenzo de

; Almeida, Dirceu

; Moises, Valdir Ambrosio

; Fonseca, Francisco A. H.

Arquivos Brasileiros de Cardiologia

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jul 2021, Volume 117 N. 1 Pages 15 - 25

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A intervenção coronária percutânea primária é considerada o “padrão-ouro” para reperfusão coronária. Entretanto, quando não disponível, a estratégia fármaco-invasiva é método alternativo, e o eletrocardiograma (ECG) tem sido utilizado para identificar sucesso na reperfusão. Objetivos Nosso estudo teve como objetivo examinar alterações no segmento-ST pós-lise e seu poder de prever a recanalização, usando os escores angiográficos TIMI e blush miocárdio (MBG) como critério de reperfusão ideal. Métodos Foram estudados 2.215 pacientes com infarto agudo do miocárdio com supra-ST submetidos à fibrinólise [(Tenecteplase)-TNK] e encaminhados para angiografia coronária em até 24 h pós-fibrinólise ou imediatamente encaminhados à terapia de resgate. O ECG foi realizado pré-TNK e 60 min-pós. Os pacientes foram categorizados em dois grupos: aqueles com reperfusão ideal (TIMI-3 e MBG-3) e aqueles com reperfusão inadequada (fluxo TIMI <3). Foi definido o critério de reperfusão do ECG pela redução do segmento ST >50%. Consideramos p-valor <0,05 para as análises, com testes bicaudais. Resultados O critério de reperfusão pelo ECG apresentou valor preditivo positivo de 56%; valor preditivo negativo de 66%; sensibilidade de 79%; e especificidade de 40%. Houve fraca correlação positiva entre a redução do segmento-ST e os dados angiográficos de reperfusão ideal (r = 0,21; p <0,001) e baixa precisão diagnóstica, com AUC de 0,60 (IC-95%; 0,57-0,62). Conclusão Em nossos resultados, a redução do segmento-ST não conseguiu identificar com precisão os pacientes com reperfusão angiográfica apropriada. Portanto, mesmo pacientes com reperfusão aparentemente bem-sucedida devem ser encaminhados à angiografia brevemente, a fim de garantir fluxo coronário macro e microvascular adequados.

Abstract Background Primary percutaneous coronary intervention is considered the “gold standard” for coronary reperfusion. However, when not available, the drug-invasive strategy is an alternative method and the electrocardiogram (ECG) has been used to identify reperfusion success. Objectives Our study aimed to assess ST-Segment changes in post-thrombolysis and their power to predict recanalization and using the angiographic scores TIMI-flow and Myocardial Blush Grade (MBG) as an ideal reperfusion criterion. Methods 2,215 patients with ST-Segment Elevation Myocardial Infarction (STEMI) undergoing fibrinolysis [(Tenecteplase)-TNK] and referred to coronary angiography within 24 h post-fibrinolysis or immediately referred to rescue therapy were studied. The ECG was performed pre- and 60 min-post-TNK. The patients were categorized into 2 groups: those with ideal reperfusion (TIMI-3 and MBG-3) and those with inadequate reperfusion (TIMI and MBG <3). The ECG reperfusion criterion was defined by the reduction of the ST-Segment >50%. A p-value <0.05 was considered for the analyses, with bicaudal tests. Results The ECG reperfusion criterion showed a positive predictive value of 56%; negative predictive value of 66%; sensitivity of 79%; and specificity of 40%. There was a weak positive correlation between ST-Segment reduction and ideal reperfusion angiographic data (r = 0.21; p <0.001) and low diagnostic accuracy, with an AUC of 0.60 (95%CI: 0.57-0.62). Conclusion The ST-Segment reduction was not able to accurately identify patients with adequate angiographic reperfusion. Therefore, even patients with apparently successful reperfusion should be referred to angiography soon, to ensure adequate macro and microvascular coronary flow.

https://doi.org/10.36660/abc.20200241 152 downloads

Prevalence evolution of SARS-CoV-2 infection in the city of São Paulo, 2020–2021
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Albuquerque, José Olimpio Moura de

; Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Pino, Francisco Alberto

; Sato, Ana Paula Sayuri

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Silva, Solange Maria Saboia e

; Caldeira, Luiz Artur Vieira

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Silva, Fabiana Érica Vilanova da

; Glasser, Paula Regina

; Burihan, Patrícia Carla Piragibe Ramos

; Cavazzana, Cinthya Luzia

; Mello, Debora Silva de

; Pellini, Alessandra Cristina Guedes

; Nishio, Fernando Yoshiki

; Kian, Fernanda Miyashiro

; Braga, Elza de Santana

; Bertelli, Nilza Maria Piassi

; Fracini, Wagner

; Gonçalves, Marcelo Dell Áquila

; Zular, Paulete Secco

; Piva, Regiane de Santana

; Masi, Eduardo

Revista de Saúde Pública

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2021, Volume 55 elocation 62

Abstract: En | Text: En | PDF: En

ABSTRACT OBJECTIVE To estimate the evolution of the prevalence of SARS-CoV-2 virus infection among residents aged 18 years or over in the municipality of São Paulo. METHODS This is a population-based household survey conducted every 15 days, between June and September 2020, and January and February 2021. In total, the study comprised 11 phases. The presence of antibodies against SARS-CoV-2 was identified in venous blood using a lateral flow test, Wondfo Biotech. In the last phase, the researchers combined it with an immunoenzymatic test, Euroimmun. The participants also answered a semi-structured questionnaire on sociodemographic and economic factors, and on social distancing measures. Prevalence estimates and the 95% confidence interval were estimated according to regions, Human Development Index, sex, age group, ethnicity, education, income, and variables associated with risk or prevention of infection. To compare the frequencies among the categories of each variable, the chi-square test with Rao-Scott correction was used, considering a significance level of 5%. RESULTS In total, 23,397 individuals were interviewed and had their samples collected. The estimated prevalence of antibodies against SARS-CoV-2 ranged from 9.7% (95%CI: 7.9–11.8%) to 25.0% (95%CI: 21.7–28.7). The prevalence of individuals with antibodies against the virus was higher among black and brown people, people with lower schooling and income, and among residents of regions with lower Human Development Index. The lowest prevalences were associated with recommended measures of disease protection. The proportion of asymptomatic infection was 45.1%. CONCLUSION The estimated prevalence of the infection was lower than the cumulative incidence variation, except for the last phase of the study. The differences in prevalence estimates observed among subpopulations showed social inequality as a risk of infection. The lower prevalence observed among those who could follow prevention measures reinforce the need to maintain social distancing measures as a way to prevent SARS-CoV-2 infection.

https://doi.org/10.11606/s1518-8787.2021055003970

10.

Prevalence evolution of SARS-CoV-2 infection in the city of São Paulo, 2020–2021
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Albuquerque, José Olimpio Moura de

; Kamioka, Gabriela Akemi

; Madalosso, Geraldine

; Costa, Selma Anequini

; Ferreira, Paula Bisordi

; Pino, Francisco Alberto

; Sato, Ana Paula Sayuri

; Carvalho, Ana Carolina Aguiar de

; Amorim, Ana Beatriz Pagliaro

; Aires, Caroline Cotrim

; Kataoka, Ana Paula Arruda Geraldes

; Savani, Elisa San Martin Mouriz

; Bessa, Thirsa Alvares Franco

; Aguiar, Breno Souza de

; Failla, Marcelo Antunes

; Santos, Edson Aparecido dos

; Brito, Edjane Maria Torreão

; Santos, Maria Cristina Honório dos

; Silva, Solange Maria Saboia e

; Caldeira, Luiz Artur Vieira

; Zamarco, Luiz Carlos

; Fonseca, Sandra Maria Sabino

; Lima, Marcia Maria de Cerqueira

; Marques, Ivanilda Argenau

; Silva, Fabiana Érica Vilanova da

; Glasser, Paula Regina

; Burihan, Patrícia Carla Piragibe Ramos

; Cavazzana, Cinthya Luzia

; Mello, Debora Silva de

; Pellini, Alessandra Cristina Guedes

; Nishio, Fernando Yoshiki

; Kian, Fernanda Miyashiro

; Braga, Elza de Santana

; Bertelli, Nilza Maria Piassi

; Fracini, Wagner

; Gonçalves, Marcelo Dell Áquila

; Zular, Paulete Secco

; Piva, Regiane de Santana

; Masi, Eduardo

Revista de Saúde Pública

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2021, Volume 55 elocation 62

Abstract: En | Text: En | PDF: En

https://doi.org/10.11606/s1518-8787.2021055003970 43 downloads

11.

Prevalence of virological and serological markers of SARS-CoV-2 infection in the population of Ribeirão Preto, Southeast Brazil: an epidemiological survey
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Martinez, Edson Zangiacomi

; Passos, Afonso Dinis Costa

; Fabbro, Amaury Lelis Dal

; Silva, Anderson Soares da

; Escarso, Andreia Cássia

; Pazin-Filho, Antônio

; Fonseca, Benedito Antônio Lopes da

; Maciel, Benedito Carlos

; Araújo, Daniel Cardoso de Almeida e

; Clé, Diego Villa

; Gaspar, Gilberto Gambero

; Santos, Jair Lício Ferreira dos

; Ferreira, Janise Braga Barros

; Souza, João Paulo

; Mello, Luane Marques de

; Santos, Luciane Loures dos

; Passos, Luzia Márcia Romanholi

; Siconelli, Márcio Junio Lima

; Cavalli, Ricardo de Carvalho

; Santana, Rodrigo de Carvalho

; Calado, Rodrigo do Tocantins

; Scarpelini, Sandro

; Bollela, Valdes Roberto

; Floriano, Vitor Gonçalves

; Bellissimo-Rodrigues, Fernando

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e0210-2021

Abstract: En | Text: En | PDF: En

Abstract INTRODUCTION: This epidemiological household survey aimed to estimate the prevalence of the current and past SARS-CoV-2 infections in Ribeirão Preto, a municipality of southeast Brazil. METHODS: The survey was conducted in two phases using a clustered sampling scheme. The first phase spanned May 1-3 and involved 709 participants. The second phase spanned June 11-14, 2020, and involved 646 participants. RESULTS: During the first phase, RT-PCR performed on nasopharyngeal swabs was positive at 0.14%. The serological tests were positive in 1.27% of the patients during the first phase and 2.79% during the second phase. People living in households with more than five members had a prevalence of 10.83% (95%CI: 1.58-74.27) higher than those living alone or with someone other. Considering the proportion of the positive serological test results with sex and age adjustments, approximately 2.37% (95%CI: 1.32-3.42) of the population had been cumulatively infected by mid-June 2020, which is equivalent to 16,670 people (95%CI: 9,267-24,074). Considering that 68 deaths from the disease in the residents of the city had been confirmed as at the date of the second phase of the survey, the infection fatality rate was estimated to be 0.41% (95%CI: 0.28-0.73). Our results suggest that approximately 88% of the cases of SARS-CoV-2 infection at the time of the survey were not reported to the local epidemiological surveillance service. CONCLUSIONS: The findings of this study provide in-depth knowledge of the COVID-19 pandemic in Brazil and are helpful for the preventive and decision-making policies of public managers.

https://doi.org/10.1590/0037-8682-0210-2021 117 downloads

12.

Pulmonary Tuberculosis in a Patient with COVID-19 Pneumonia
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Fonseca Jr, Cyro Antonio

; Zanetti, Gláucia

; Marchiori, Edson

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e0314-2021

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0037-8682-0314-2021 79 downloads

13.

Bazo errante infartado y vólvulo de cola de páncreas en un paciente con hernia de Grynfelt-Lesshaft concomitante
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Saldívar-Martínez, Daniel E.

; Galindo-Sánchez, Héctor M.

; Fonseca-Sada, Ignacio

; Marcos-Ramírez, Edson R.

; Vázquez-Fernández, Francisco

Cirugía y cirujanos

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2021, Volume 89 Suppl. 1 Pages 20 - 22

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Wandering spleen is a rare condition, generally due to congenital abnormalities of the dorsal mesogastrium or splenic suspensory ligaments and not traumatic events. The most frequent complication is torsion of the splenic hilus with ischemia or splenic infarction and its association with pancreatic volvulus is extremely rare. There are no reported cases of wandering spleen with pancreatic volvulus in association with a post traumatic Grynfelt-Lesshaft haernia. We present a case of a 43-year-old female patient with an association of these three entities and a history of abdominal trauma.

Resumen El bazo errante es una afección rara que en general se debe a anomalías congénitas del mesogastrio dorsal o de los ligamentos suspensores esplénicos, y no a traumatismos. La complicación más frecuente es la torsión del hilio esplénico con isquemia o infarto esplénico, y su asociación a vólvulo pancreático es extremadamente rara. No existen ningún otro caso reportado de bazo errante con vólvulo pancreático en un paciente que presenta una hernia lumbar de Grynfelt-Lesshaft postraumática. Presentamos el caso de una paciente de 43 años con asociación de estas tres afecciones y antecedente de traumatismo abdominal.

https://doi.org/10.24875/ciru.20000813 36 downloads

14.

BIONANOCOMPÓSITOS POLIMÉRICOS À BASE DE MONTMORILLONITA – MATERIAIS DE INTERESSE CONTÍNUO
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França, Denise B.

; Alcântara, Ana C. S.

; Silva-Filho, Edson C.

; Fonseca, Maria G.

Química Nova

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dec 2020, Volume 43 N. 10 Pages 1447 - 1462

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Polymeric bionanocomposites are versatile materials that have many practical applications. The wide use of these materials is mainly due to their structure and properties, which combine at nanometric scale, the functionality of biopolymers with the excellent stability of inorganic solids, such as the clay minerals family. Montmorillonite is the most widely employed clay mineral in the development of polymeric bionanocomposites. The resulting materials from the combination of biopolymers and montmorillonite clay can form different structures (layered, delaminated, and exfoliated phases) and morphologies (powder, films or beads), exhibiting new features and better chemical, mechanical, thermal, and gas barrier properties compared to the pristine matrices, owing to the synergistic effect between both organic and inorganic moieties. In this sense, this review addresses polymeric bionanocomposites originating from the interaction between montmorillonite and chitosan and cellulose biopolymers. The synthesis, characteristics, and main applications of polymeric bionanocomposites have been reported, and in some cases, the relationship between the formed structures and final properties of bionanocomposites is also highlighted.

https://doi.org/10.21577/0100-4042.20170602 226 downloads

15.

Management of Hepatocellular Carcinoma during the COVID-19 Pandemic - São Paulo Clínicas Liver Cancer Group Multidisciplinary Consensus Statement
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Chagas, Aline Lopes

; da Fonseca, Leonardo Gomes

; Coelho, Fabricio Ferreira

; da Cunha Saud, Lisa Rodrigues

; Abdala, Edson

; Andraus, Wellington

; Fiore, Lucas

; Moreira, Airton Mota

; Menezes, Marcos Roberto

; Carnevale, Francisco César

; Tani, Claudia Megumi

; Alencar, Regiane S.S.M

; D'Albuquerque, Luiz Augusto Carneiro

; Herman, Paulo

; Carrilho, Flair José

Clinics

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2020, Volume 75 elocation e2192

Abstract: En | Text: En | PDF: En

More than 18 million people in 188 countries have been diagnosed as having coronavirus disease (COVID-19), and COVID-19 has been responsible for more than 600,000 deaths worldwide. Brazil is now the second most affected country globally. Faced with this scenario, various public health measures and changes in the daily routines of hospitals were implemented to stop the pandemic. Patients with hepatocellular carcinoma (HCC) are at an increased risk for severe COVID-19 as they present with two major diseases: cancer and concomitant chronic liver disease. The COVID-19 pandemic can significantly impact the management of HCC patients from diagnosis to treatment strategies. These patients need special attention and assistance at this time, especially since treatment for tumors cannot be delayed in most cases. The aim of this guideline was to standardize the management of HCC patients during the COVID-19 pandemic. This document was developed, on the basis of the best evidence available, by a multidisciplinary team from Instituto do Câncer do Estado de São Paulo (ICESP), and Instituto Central of the Hospital das Clínicas da Universidade de São Paulo (HC-FMUSP), which are members of the São Paulo Clínicas Liver Cancer Group.

https://doi.org/10.6061/clinics/2020/e2192 361 downloads

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