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ABSTRACT Lettuce (Lactuca sativa) is the most economically important leafy vegetable in Brazil, with the crisp type being the most popular among producers. However, in regions with hot climates, lettuce has production limitations due to bolting, requiring knowledge on the behavior of cultivars available on the market. Thus, the objective of the present study was to characterize the performance of crisp lettuce cultivars in terms of their productive, physiological, and postharvest quality aspects when grown under hydroponic cultivation and high temperature conditions. The assay was performed in a greenhouse and the plants were grown in a hydroponic system of DFT type. The average temperature during the experiment was 30.33 °C. The experimental design used was completely randomized with nine treatments (Veneranda, Cristina, Olinda, Mônica, Cinderela, Grand Rapids, Itapuã Super, Crocantela, and Simpson Black Seed), with four replications. The cultivars were analyzed in terms of their productive, physiological, and postharvest quality performances. The Olinda and Cristina cultivars showed the best performance in growth, physiological, and postharvest variables. However, the cultivars had distinct sensory characteristics. Bolting negatively affected gas exchange, production, and postharvest quality of lettuce cultivars Veneranda, Mônica, Grand Rapids, and Cinderela. In addition, it was observed that the pigment content was not determinant for the expression of bolting. Therefore, this study recommends the use of cultivars Olinda and Cristina for the hydroponic cultivation under high temperature conditions. Lactuca sativa Brazil producers However climates bolting market Thus productive physiological conditions 3033 30 33 30.3 C °C Veneranda (Veneranda Mônica Cinderela Rapids Super Crocantela Seed, Seed , Seed) replications performances growth variables characteristics exchange addition Therefore 303 3 30.

RESUMO A alface (Lactuca sativa) é a hortaliça folhosa de maior importância econômica no Brasil, sendo o tipo crespa a mais popular entre os produtores. Entretanto, em regiões de clima quente, a alface apresenta limitações de produção devido ao pendoamento precoce, exigindo o conhecimento do comportamento das cultivares disponíveis no mercado. Assim, o objetivo do presente estudo foi caracterizar o desempenho de cultivares de alface crespa quanto aos aspectos produtivos, fisiológicos e de qualidade pós-colheita, cultivadas em condições de cultivo hidropônico e alta temperatura. O ensaio foi conduzido em condição de casa de vegetação, sendo as plantas cultivadas em sistema hidropônico tipo DFT. A temperatura média durante o experimento foi de 30,33 °C. O delineamento experimental utilizado foi o inteiramente casualizado com nove tratamentos (Veneranda, Cristina, Olinda, Mônica, Cinderela, Grand Rapids, Itapuã Super, Crocantela e Simpson Black Seed) e quatro repetições. As cultivares foram analisadas quanto ao seu desempenho produtivo, fisiológico e de qualidade pós-colheita. As cultivares Olinda e Cristina apresentaram melhor desempenho nos parâmetros de crescimento, fisiológicos e pós-colheita. Entretanto, estas cultivares apresentaram características sensoriais distintas. Verificou-se que o pendoamento precoce afetou negativamente as trocas gasosas, a produção e a qualidade pós-colheita das cultivares de alface Veneranda, Mônica, Grand Rapids e Cinderela. Além disso, observou-se que o teor de pigmentos não foi determinante para a expressão do pendoamento. Portanto, este estudo recomenda o uso das cultivares Olinda e Cristina para o cultivo hidropônico em condições de alta temperatura. Lactuca sativa Brasil produtores Entretanto quente mercado Assim produtivos póscolheita, póscolheita pós colheita, colheita vegetação DFT 3033 30 33 30,3 C °C Veneranda (Veneranda Mônica Cinderela Super Seed repetições produtivo póscolheita. colheita. crescimento distintas Verificouse Verificou se gasosas disso observouse observou Portanto 303 3 30,

https://doi.org/10.1590/1807-1929/agriambi.v28n5e277774

Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives
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Rosa, Bruno

; Andrade, Patrícia

; Lopes, Sandra

; Gonçalves, Ana Rita

; Serrazina, Juliana

; Cardoso, Pedro Marílio

; Silva, Andrea

; Silva, Vítor Macedo

; Cotter, José

; Macedo, Guilherme

; Figueiredo, Pedro Narra

; Chagas, Cristina

GE-Portuguese Journal of Gastroenterology

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apr 2024, Volume 31 N. 2 Pages 13 - 24

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background: The role of capsule endoscopy in the evaluation of the small bowel is well established, and current guidelines position it as a ﬁrst-line test in a variety of clinical scenarios. The advent of double-headed capsules further enabled the endoscopic assessment of colonic mucosa and the opportunity for a one-step noninvasive examination of the entire bowel (panenteric capsule endoscopy [PCE]). Summary: We reviewed the technical procedure and preparation of patients for PCE, as well as its current clinical applications and future perspectives. In non-stricturing and non-penetrating Crohn’sdisease affecting the small bowel and colon, PCE monitors disease activity by assessing mucosal healing, a major treatment outcome, with a higher diagnostic yield than cross-sectional imaging or conventional colonoscopy. Also in ulcerative colitis, double-headed capsules have been used to monitor disease activity noninvasively. Currently, validated scoring systems have been speciﬁcally devised for these double-headed capsules and permit a standardized assessment of the inﬂammatory burden. In suspected mid-lower digestive bleeding, some exploratory studies have demonstrated the feasibility and high diagnostic yield of PCE, which may work as a ﬁlter indicating which patients may beneﬁt of further invasive procedures, namely, for planned hemostatic procedures. The possibility of using PCE is also discussed in the context of polyposis syn-dromes with simultaneous involvement of the small intestine and colon. Key Messages: PCE is a feasible, effective, and safe diagnostic procedure to evaluate the small bowel and colon. It has been increasingly explored in the setting of inﬂammatory bowel diseases and, more recently, in suspected mid-lower digestive bleeding. PCE is expected to reduce the demand for invasive procedures and expand the scope of noninvasive intestinal evaluation in the coming future.

Resumo Introdução: O papel da endoscopia por cápsula na avaliação do intestino delgado encontra-se bem estabelecido, e as orientações atuais posicionam-na como um teste de primeira linha numa variedade de cenários clínicos. O advento das cápsulas de dupla câmara permitiu expandir a sua aplicação para a avaliação endoscópica da mucosa do cólon, oferecendo a oportunidade de um exame não invasivo de todo o intestino (endoscopia pan-entérica por cápsula, PCE). Sumário: Procedemos a uma revisão de vários aspectos do procedimento e preparação dos doentes para a PCE, bem como as aplicações clínicas atuais e as perspetivas futuras das cápsulas de dupla câmara. Na doença de Crohn não estenosante e não penetrante localizada ao intestino delgado e cólon, a PCE permite monitorizar a atividade da doença e avaliar a cicatrização da mucosa, um indicador importante da eﬁcácia da terapêutica, com um rendimento de diagnóstico superior aos métodos convencionais, nomeadamente os exames imagiológicos ou a colonoscopia invasiva. Também na colite ulcerosa, as cápsulas de dupla câmara têm sido utilizadas para monitorizar a atividade da doença de forma não invasiva. Existem índices endoscópicos validados e especiﬁcamente concebidos para as cápsulas de dupla câmara, que permitem uma avaliação sistematizada e quantiﬁcação objetiva da atividade inﬂamatória. Na suspeita de hemorragia digestiva média ou baixa, alguns estudos exploratórios demonstraram a aplicabilidade e o elevado rendimento diagnóstico da PCE, podendo funcionar como um ﬁltro de modo a permitir indicar quaisosdoentesquemaisirãobeneﬁciar de um procedimento invasivo subsequente, nomeadamente para arealizaçãodeprocedimentos hemostáticos dirigidos. A possibilidade de utilização da PCE é também discutida no contexto das síndromes de polipose com envolvimento simultâneo do intestino delgado e do cólon. Mensagens-chave: A PCE é um procedimento diagnóstico eﬁcaz e seguro para avaliar diretamente a mucosa do intestino delgado e cólon. A sua aplicação tem vindo a expandir-se no contexto das Doenças Inﬂamatórias Intestinais e, mais recentemente, na suspeita de hemorragia digestiva média ou baixa. Existe a expectativa de que no futuro próximo possamos assistir a uma redução substancial da demanda por procedimentos endoscópicos invasivos, face à utilização crescente da PCE enquanto método de diagnóstico pan-intestinal não invasivo.

https://doi.org/10.1159/000533960

[SciELO Preprints] - Guidelines on the Diagnosis and Treatment of Hypertrophic Cardiomyopathy – 2024
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Fernandes, Fabio Simões, Marcus V. Correia, Edileide de Barros Marcondes-Braga, Fabiana G. Coelho-Filho, Otavio Rizzi Mesquita, Cláudio Tinoco Mathias-Junior, Wilson Rochitte, Carlos Eduardo Ramires, Felix José Alvarez Alves, Silvia Marinho Martins Montera, Marcelo Westerlund Lopes, Renato Delascio Oliveira-Junior, Mucio Tavares Scolari, Fernando L. Avila, Walkiria Samuel Canesin, Manoel Fernandes Bacal, Fernando Bocchi, Edimar Alcides Moura, Lídia Ana Zytynski Saad, Eduardo Benchimol Scanavacca, Mauricio I. Valdigem, Bruno Pereira Cano , Manuel Nicolas Abizaid , Alexandre Ribeiro, Henrique Barbosa Lemos-Neto, Pedro Alves Ribeiro, Gustavo Calado de Aguiar Jatene, Fabio Biscegli Dias, Ricardo Ribeiro Beck-da-Silva, Luis Rohde, Luis Eduardo P. Bittencourt, Marcelo Imbroinise Pereira, Alexandre Krieger, José Eduardo Villacorta, Humberto Martins, Wolney de Andrade Figueiredo-Neto, José Albuquerque de Cardoso , Juliano Novaes Pastore, Carlos Alberto Jatene, Ieda Biscegli Tanaka, Ana Cristina Sayuri Hotta, Viviane Tiemi Romano, Minna Moreira Dias Albuquerque, Denilson Campos de Mourilhe-Rocha, Ricardo Hajjar, Ludhmila Abrahão Brito, Fabio Sandoli de Caramelli , Bruno Calderaro, Daniela Farsky, Pedro Silvio Colafranceschi , Alexandre Siciliano Pinto, Ibraim Masciarelli Vieira , Marcelo Luiz Campos Danzmann, Luiz Claudio Barberato , Silvio Henrique Mady, Charles Martinelli-Filho, Martino Torbey , Ana Flavia Malheiros Schwartzmann, Pedro Vellosa Macedo, Ariane Vieira Scarlatelli Ferreira , Silvia Moreira Ayub Schmidt, Andre Melo , Marcelo Dantas Tavares de Lima-Filho, Moysés Oliveira Sposito, Andrei C. Brito, Flavio de Souza Biolo, Andreia Madrini-Junior, Vagner Rizk, Stéphanie Itala Mesquita, Evandro Tinoco

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Publication date: 2024-04-08

Abstract: Pt Es En

A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI).

La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.

https://doi.org/10.1590/SciELOPreprints.8394

Consensus of the Brazilian Association of Hematology, Hemotherapy and Cellular Therapy (ABHH) and the Brazilian Ministry of Health - General management of blood and blood products on the tests necessary for the release of exceptional medicines for sickle cell disease Hematology ABHH (ABHH
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Lobo, Clarisse

; Araújo, Aderson

; Antunes, Alexandre de Albuquerque

; Pinto, Ana Cristina Silva

; Godinho, Ariadne Carvalho

; Pires, Cassia Silvestre Mariano

; Matheus, Cinthia Cristina

; Albuquerque, Xerez de

; Neves, Daniele Campos Fontes

; Moreno, Fábio de Lima

; Baldanzi, Giorgio

; Siufi, Grazziella Curado

; Miranda, Heloisa Helena Pereira

; Hankins, Jane

; Aragão, Joice

; Braga, Josefina Aparecida Pellegrini

; Martins, Juliana Touguinha Neves

; Souza, Luciana Campos Costa Machado de

; Figueiredo, Maria Stella

; Oliveira, Mirella Rodrigues

; Cardoso, Patricia Santos Resende

; Pinto, Patricia Costa Alves

; Moura, Patricia Gomes

; Cançado, Rodolfo Delfini

; Araujo, Paulo Ivo Cortez de

; Saad, Sara Olalla

; Loggetto, Sandra Regina

; Fonseca, Teresa Cristina Cardoso

Hematology, Transfusion and Cell Therapy

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mar 2024, Volume 46 N. 1 Pages 67 - 71

Abstract: En | Text: En | PDF: En

Abstract To date, hydroxyurea is the only effective and safe drug that significantly reduces morbidity and mortality of individuals with Sickle cell disease. Twenty years of real-life experience has demonstrated that hydroxyurea reduces pain attacks, vaso-occlusive events, including acute chest syndrome, the number and duration of hospitalizations and the need for transfusion. The therapeutic success of hydroxyurea is directly linked to access to the drug, the dose used and adherence to treatment which, in part, is correlated to the availability of hydroxyurea. This consensus aims to reduce the number of mandatory exams needed to access the drug, prioritizing the requesting physician's report, without affecting patient safety. date disease reallife real life attacks vasoocclusive vaso occlusive events syndrome transfusion which part physicians physician s report safety

https://doi.org/10.1016/j.htct.2024.01.001

Steps of cryopreservation of coffee seeds: physiological responses and antioxidant systems seeds
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Souza, Ana Cristina de

; Costa, Marina Chagas

; Figueiredo, Madeleine Alves de

; Pereira, Cristiane Carvalho

; Coelho, Stefânia Vilas Boas

; Vilela, Ana Luiza Oliveira

; Pereira, Diego de Souza

; Rosa, Sttela Dellyzete Veiga Franco da

Ciência Rural

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2024, Volume 54 N. 2 elocation e20220480

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT: The cryopreservation of plant germplasm at ultralow temperatures is an alternative technique for the long-term storage of seeds of the genus Coffea sp. However, for this technique to be successful, cell integrity must be maintained at all stages of the process on the basis of scientific research. The present study investigated validated cryopreservation protocols for Coffea arabica L. seeds and evaluate the effects on the physiological and biochemical characteristics of the seeds at each stage of the process. Seeds were dried on silica gel or with saturated saline solution, precooled or not in a biofreezer, immersed in nitrogen, and reheated in a water bath. After each of these steps, the physiological and biochemical quality of the seeds was determined. Pre-cooling is a step that can be dispensed with in the cryopreservation of Coffea arabica seeds, direct immersion in liquid nitrogen being more indicated. Coffea arabica L. seeds tolerate cryopreservation after rapid drying in silica gel up to water contents of 17 or 20% (wb), with greater survival at 17%. The enzyme activities of catalase, polyphenol oxidase and peroxidase are indicators of the quality of C. arabica L. seeds subjected to cryopreservation. ABSTRACT longterm long term sp However successful research L solution biofreezer bath steps determined Precooling Pre cooling indicated 1 20 wb, wb , (wb) 17% catalase C 2 (wb

RESUMO: A criopreservação de germoplasma vegetal em temperaturas ultrabaixas é uma alternativa para o armazenamento em longo prazo de sementes do gênero Coffea sp. Entretanto, para que essa técnica apresente sucesso, a realização de pesquisas que garantam a manutenção da integridade celular em todas as etapas do processo é de fundamental importância. O objetivo com o presente trabalho foi investigar protocolos de criopreservação validados para sementes de Coffea arabica L., avaliando separadamente, os efeitos sobre as características fisiológicas e bioquímicas das sementes, em cada etapa do processo. As sementes foram secadas em sílica gel ou em solução salina saturada, submetidas ou não ao pré-resfriamento em biocongelador, em seguida imersas no nitrogênio e reaquecidas em banho-maria. Após cada uma dessas etapas, a qualidade fisiológica e bioquímica das sementes foi determinada. O pré-resfriamento é uma etapa que pode ser dispensada na criopreservação de sementes de Coffea arabica, sendo mais indicada a imersão direta em nitrogênio líquido. Sementes de Coffea arabica L. toleram a criopreservação após secagem rápida em sílica gel até teores de água de 17 ou 20% (wb), com maior sobrevivência a 17%. A atividade das enzimas catalase, polifenoloxidase e peroxidase são indicadoras da qualidade de sementes de Coffea arabica L. submetidas à criopreservação. RESUMO sp Entretanto sucesso importância L separadamente saturada préresfriamento pré resfriamento biocongelador banhomaria. banhomaria banho maria. maria banho-maria determinada líquido 1 20 wb, wb , (wb) 17% catalase 2 (wb

https://doi.org/10.1590/0103-8478cr20220480

Adequação do Consumo de Ácidos Graxos entre Pacientes em Prevenção Cardiovascular Secundária
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Marcadenti, Aline

; Machado, Rachel H. Vieira

; Santos, Renato Hideo Nakagawa

; Kasai, Caio Cesar dos Santos

; Kovacs, Cristiane

; Bello, Annie

; de Matos, Cristina H.

; Bertacco, Renata Torres Abib

; Souza, Gabriela C.

; Schirmann, Gabriela da S.

; Nagano, Francisca Eugenia Zaina

; Poloni, Soraia

; Kik, Raquel Milani El

; Feres, Naoel Hassan

; Rodrigues, Isa G.

; Sousa, Antônio Carlos Sobral

; Pinheiro, Josilene M. F.

; Vasconcelos, Sandra Mary Lima

; Carlos, Daniele Maria de Oliveira

; Souza, Viviane Sahade

; Gomes, Adriana Barros

; Figueiredo Neto, José Albuquerque de

; Moriguchi, Emilio Hideyuki

; Izar, Maria Cristina

; Pinto, Sônia Lopes

; Bressan, Josefina

; de Souza, Simone Raimondi

; Kumbier, Magali C.

; de Araújo, Celme Barroncas Passos

; Torreglosa, Camila R.

; Weber, Bernardete

; Bersch-Ferreira, Ângela Cristine

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 3 elocation e20230487

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Background: Adhering to a diet adequate in macronutrients is crucial for the secondary prevention of cardiovascular diseases. Objective: To assess the prevalence of adherence to recommendations for the consumption of dietary fatty acids for the prevention and treatment of cardiovascular diseases and to estimate whether the presence of certain cardiovascular risk factors would be associated with adherence. Methods: Cross-sectional study using baseline data from 2,358 participants included in the "Brazilian Cardioprotective Nutritional Program Trial". Dietary intake and cardiovascular risk factors were assessed. Adequate intake of polyunsaturated fatty acids (PUFA) was considered as ≥10% of total daily energy intake; for monounsaturated fatty acids (MUFA), 20%; and for saturated fatty acids (SFA), <7% according to the Brazilian Society of Cardiology. A significance level of 5% was considered in the statistical analysis. Results: No participant adhered to all recommendations simultaneously, and more than half (1,482 [62.9%]) did not adhere to any recommendation. Adherence exclusively to the SFA recommendation was the most prevalent, fulfilled by 659 (28%) participants, followed by adherence exclusively to the PUFA (178 [7.6%]) and MUFA (5 [0.2%]) recommendations. There was no association between the number of comorbidities and adherence to nutritional recommendations (p = 0.269). Participants from the Brazilian Northeast region showed a higher proportion of adherence to SFA consumption recommendations (38.42%) and lower adherence to PUFA intake (3.52%) (p <0.001) compared to other regions. Conclusions: Among the evaluated sample, there was low adherence to nutritional recommendations for dietary fatty acid consumption. Background Objective Methods Crosssectional Cross sectional 2358 2 358 2,35 Trial. Trial . Trial" assessed (PUFA 10 ≥10 MUFA, , (MUFA) 20% 20 SFA, (SFA) 7 <7 Cardiology 5 analysis Results simultaneously 1,482 1482 1 482 (1,48 62.9% 629 62 9 [62.9%] prevalent 65 28% 28 (28% 178 (17 7.6% 76 6 [7.6%] ( 0.2% 02 0 [0.2%] p 0.269. 0269 0.269 269 0.269) 38.42% 3842 38 42 (38.42% 3.52% 352 3 52 (3.52% <0.001 0001 001 regions Conclusions sample 235 35 2,3 ≥1 (MUFA (SFA < 1,48 148 48 (1,4 62.9 [62.9% (28 17 (1 7.6 [7.6% 0.2 [0.2% 026 0.26 26 38.42 384 4 (38.42 3.52 (3.52 <0.00 000 00 23 2, ≥ 1,4 14 (1, 62. [62.9 (2 7. [7.6 0. [0.2 38.4 (38.4 3.5 (3.5 <0.0 1, [62. [7. [0. 38. (38. 3. (3. <0. [62 [7 [0 (38 (3 <0 [6 [

Resumo Fundamento: A adesão à uma alimentação adequada em macronutrientes é fundamental para a prevenção secundária de doenças cardiovasculares. Objetivo: Avaliar a prevalência de adesão às recomendações de consumo de ácidos graxos para prevenção e tratamento de doenças cardiovasculares, e estimar se a presença de determinados fatores de risco cardiovascular estaria associada à adesão. Métodos: Estudo transversal com os dados de linha de base de 2358 participantes do estudo "Brazilian Cardioprotective Nutritional Program Trial". Dados de consumo alimentar, e fatores de risco cardiovascular foram avaliados. Foi considerada, de acordo com a Sociedade Brasileira de Cardiologia, uma ingestão adequada de ácidos graxos poli-insaturados (AGPI) ≥10% do consumo total de energia diária, para ácidos graxos monoinsaturados (AGM), 20% e para ácidos graxos saturados (AGS), <7%. Na análise estatística foi considerando nível de significância de 5%. Resultados: Nenhum participante aderiu a todas as recomendações de forma simultânea e mais da metade (1482 [62,9%]) não aderiu a nenhuma recomendação. A adesão exclusivamente à recomendação de AGS foi a mais prevalente, sendo cumprida por 659 (28%) dos participantes, seguida da adesão exclusivamente à recomendação de AGP (178 [7,6%]) e de AGM (5 [0,2%]). Não houve associação entre o número de comorbidades e a adesão às recomendações nutricionais (p =0,269). Os participantes da região Nordeste do país apresentaram maior proporção de adesão às recomendações para consumo de AGS (38,42%), e menor para ingestão de AGPI (3,52%) (p <0,001) em comparação às demais. Conclusões: Na amostra avaliada, evidenciou-se baixa adesão às recomendações nutricionais para consumo de ácidos graxos. Fundamento cardiovasculares Objetivo Métodos 235 Brazilian Trial. Trial . Trial" alimentar avaliados considerada Cardiologia poliinsaturados poli insaturados (AGPI 10 ≥10 diária AGM, , (AGM) 20 AGS, (AGS) 7 <7% 5 5% Resultados 1482 (148 62,9% 629 62 9 [62,9%] prevalente 65 28% 28 (28% 178 (17 7,6% 76 6 [7,6%] ( 0,2%. 02 0,2% 0 2 [0,2%]) p =0,269. 0269 =0,269 269 =0,269) 38,42%, 3842 38,42% 38 42 (38,42%) 3,52% 352 3 52 (3,52% <0,001 0001 001 demais Conclusões avaliada evidenciouse evidenciou 23 1 ≥1 (AGM (AGS <7 148 (14 62,9 [62,9% (28 17 (1 7,6 [7,6% 0,2 [0,2%] 026 =0,26 26 384 38,42 4 (38,42% 3,52 35 (3,52 <0,00 000 00 ≥ < 14 62, [62,9 (2 7, [7,6 0, [0,2% =0,2 38,4 (38,42 3,5 (3,5 <0,0 [62, [7, [0,2 =0, 38, (38,4 3, (3, <0, [62 [7 [0, =0 (38, (3 <0 [6 [ [0 = (38

https://doi.org/10.36660/abc.20230487

Autoavaliação como estratégia de planejamento em um programa de pósgraduação
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Rossit, Rosana Aparecida Salvador

; Poletto, Patrícia Rios

; Uchôa-Figueiredo, Lúcia da Rocha

; Lopes, Káthia Ferraro

; Mazzaia, Maria Cristina

Avaliação: Revista da Avaliação da Educação Superior (Campinas)

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2024, Volume 29 elocation e024002

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen La autoevaluación se caracteriza por un proceso de autoanálisis realizado colectivamente por los actores involucrados en el proceso, destacando fortalezas, debilidades y oportunidades de mejora. La autoevaluación representa un esfuerzo colectivo para implementar un proceso de reflexión crítica, democrática y participativa. Este artículo tiene como objetivo presentar el proceso de formación y actuación del Comité de Autoevaluación (CAA) del Programa de Posgrado en Ciencias de la Salud-Maestría Profesional de la Universidade Federal de São Paulo en el período 2021 y 2022. Se desarrolló un Plan de Autoevaluación mediante un grupo de trabajo constituido en el ámbito del CAA, con la participación de miembros del Comité Docente de Posgrado y una reunión ampliada con profesores y estudiantes. El plan abordó la importancia de la autoevaluación como una poderosa estrategia de planificación e intervenciones en busca de mejoras al Programa. Para lograr sus objetivos, CAA basó sus acciones en la propuesta PDSA (plan-do-study-action). El proceso resultó en el involucramiento de diferentes actores para crear el Plan de Autoevaluación e implementar acciones prioritarias en el corto y mediano plazo. fortalezas mejora crítica participativa (CAA SaludMaestría Salud Maestría 202 2022 estudiantes objetivos plandostudyaction. plandostudyaction do study action . (plan-do-study-action) plazo 20 (plan-do-study-action 2

Abstract Self-assessment is characterized by a self-analysis process carried out collectively by the actors involved in the process, highlighting strengths, weaknesses and opportunities for improvement. Selfassessment represents a collective effort to implement a process of critical, democratic and participatory reflection. This article aims to present the process of formation and performance of the Self-Assessment Committee (SAC) of the Graduate Program in Health Sciences-Professional Master’s at the Universidade Federal de São Paulo in 2021 and 2022. A Self-Assessment Plan was developed by a working group constituted within the scope of SAC, with the participation of members of the Graduate Teaching Committee and an extended meeting with professors and students. The plan addressed the importance of self-assessment as a powerful strategy for planning and interventions in search of improvements to the program. To achieve its objectives, SAC based its actions on the PDSA proposal (plan-do-study-action). The process resulted in the involvement of different actors to create the Self-Assessment Plan and implement priority actions in the short and medium term. Self assessment selfanalysis self analysis strengths improvement critical reflection SelfAssessment Assessment (SAC SciencesProfessional Sciences Professional Masters Master s 202 2022 students selfassessment program objectives plandostudyaction. plandostudyaction do study action . (plan-do-study-action) term 20 (plan-do-study-action 2

Resumo A autoavaliação caracteriza-se por um processo de autoanálise realizada coletivamente pelos atores envolvidos no processo, destacando as potencialidades, as fragilidades e as oportunidades de melhorias. A autoavaliação representa um esforço coletivo para a implementação de um processo de reflexão crítica, democrática e participativa. Este artigo tem por objetivo apresentar o processo de formação e atuação da Comissão de Autoavaliação (CAA) do Programa de Pós-Graduação Ensino em Ciências da Saúde-Mestrado Profissional da Universidade Federal de São Paulo no período de 2021 e 2022. Um Plano de Autoavaliação foi desenvolvido por um grupo de trabalho constituído no âmbito da CAA, com participação de membros da Comissão de Ensino de Pós-Graduação e de reunião ampliada com docente e discente. O plano abordou a importância da autoavaliação como estratégia potente para o planejamento e intervenções em busca de melhorias do programa. Para o alcance dos objetivos, a CAA fundamentou suas ações na proposta PDSA (plan-do-study-action). O processo resultou em envolvimento de diferentes atores para a construção do Plano de Autoavaliação e implementação de ações prioritárias a curto e médio prazo. caracterizase caracteriza se potencialidades crítica participativa (CAA PósGraduação Pós Graduação SaúdeMestrado Saúde Mestrado 202 2022 discente programa objetivos plandostudyaction. plandostudyaction plan study action . (plan-do-study-action) prazo 20 (plan-do-study-action 2

https://doi.org/10.1590/1982-57652024v29id272994

Prevalence and reasons for referrals to the Endodontics Specialty Clinic at the Piracicaba Dental School
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RAMOS, Jéssica Rodrigues

; BRONZATO, Juliana Delatorre

; BICEGO-PEREIRA, Eloa Cristina

; DE-JESUS-SOARES, Adriana

; MARCIANO, Marina Angelica

; ALMEIDA, José Flávio Affonso

; FERRAZ, Caio Cezar Randi

; GOMES, Brenda Paula Figueiredo de Almeida

Brazilian Oral Research

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2024, Volume 38 elocation e008

Abstract: En | Text: En | PDF: En

Abstract Dental referrals to the Endodontics Specialty Clinic (ESC) are routine owing to the complexity of endodontic treatments. To obtain a better prognosis for treatment, students/dentists must perceive their technical limits. This study sought to investigate the referrals of patients to the ESC from different clinics of the Piracicaba Dental School, State University of Campinas - SP, Brazil, and check: a) the demographic profile of patients and the most commonly affected tooth; b) the clinic with the largest number of referrals; c) the reasons for referrals; d) the complexity of the cases; e) and the difficulty in assessing the referred cases based on the classification provided by the American Association of Endodontists (AAE) and Souza-Filho. The study sample consisted of patients’ electronic dental referral records from February 2015 to June 2019. A total of 1,707 patients were referred to the ESC during the study period, and 62.4% were female. Lower molars were the most frequently involved teeth (34.8%), and 60.7% of the cases were referred due to the presence of root curvature. The AAE classification showed prevalence of highly difficult cases (71.3%), whereas Souza-Filho classification demonstrated a high rate of class III cases (85.8%). This study highlights the difficulties encountered by undergraduate students before or during endodontic treatments, reinforcing the need for clear criteria for selecting cases appropriate for each education level, thus improving endodontic treatment prognosis. (ESC treatments studentsdentists dentists limits School SP Brazil check tooth b c d e (AAE SouzaFilho. SouzaFilho Souza Filho. Filho 201 2019 1707 1 707 1,70 period 624 62 4 62.4 female 34.8%, 348 34.8% , 34 8 (34.8%) 607 60 7 60.7 curvature 71.3%, 713 71.3% 71 3 (71.3%) 85.8%. 858 85.8% . 85 (85.8%) level 20 170 70 1,7 6 62. 34.8 (34.8% 60. 71.3 (71.3% 85.8 (85.8% 2 17 1, 34. (34.8 71. (71.3 85. (85.8 (34. (71. (85. (34 (71 (85 (3 (7 (8 (

https://doi.org/10.1590/1807-3107bor-2024.vol38.0008

Adapting the Nominal Group Technique to a virtual version: an experience report version
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Gusmão, Viviane Cristina de Lima

; Flausino, Tatiane Garcia do Carmo

; Couto, Daniela Sanches

; Abraão, Ligia Maria

; Felix, Adriana Maria da Silva

; Ciofi-Silva, Caroline Lopes

; Courtenay, Molly

; Ness, Valerie

; Castro-Sanchez, Enrique

; Figueiredo, Rosely Moralez de

; Padoveze, Maria Clara

Revista da Escola de Enfermagem da USP

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2024, Volume 58 elocation e20230298

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivo: Informar sobre las adaptaciones realizadas a la Técnica de Grupo Nominal (TGN) original, permitiendo su aplicación al formato virtual, preservando todos sus elementos clave. Método: Se trata de un informe de experiencia sobre las adaptaciones y ajustes realizados a la TGN original para el formato virtual mediante el uso de las Tecnologías de la Información y la Comunicación (TIC), utilizando herramientas digitales disponibles de forma gratuita o de bajo coste y fácil uso. Resultados: El TGN se realizó íntegramente de manera virtual y sufrió adaptaciones en cada una de sus cuatro etapas mediante la incorporación de recursos digitales específicos. Fue posible presentar las ideas más votadas y obtener la aprobación final de los participantes. Los participantes no tuvieron dificultades para utilizar los recursos virtuales proporcionados y, según los comentarios recibidos, se mostraron satisfechos con las herramientas facilitadas. Conclusión: El TGN adaptado demostró ser un método eficaz cuando se utiliza en un entorno virtual, capaz de producir un número significativo de ideas y desarrollar el consenso. La herramienta adaptada puede ser utilizada por otros investigadores en países con recursos o dimensiones similares a las de Brasil. Objetivo (TGN clave Método TIC, TIC , (TIC) Resultados específicos recibidos facilitadas Conclusión consenso Brasil (TIC

ABSTRACT Objective: To report on the adaptations made to the original Nominal Group Technique (NGT), allowing it to be applied to the virtual format, preserving all its key elements. Method: An experience report on the adaptations and adjustments made to the original NGT to the virtual format using Information and Communication Technologies (ICT), using digital tools that are available free of charge or are low cost and easy to use. Results: The NGT was carried out entirely virtually and underwent adaptations in each of its four stages through the incorporation of specific digital resources. It was possible to present the most voted ideas and obtain final approval from the participants. The participants had no difficulty in using the virtual resources provided and, based on the reaction evaluation, they were satisfied with the tools provided. Conclusion: The adapted NGT proved to be an effective method when used in a virtual setting, capable of producing a significant number of ideas and developing consensus. The adapted tool can be used by other researchers in countries with similar resources or dimensions to Brazil. Objective NGT, , (NGT) elements Method ICT, ICT (ICT) use Results evaluation Conclusion setting consensus Brazil (NGT (ICT

RESUMO Objetivo: Relatar as adaptações realizadas na Técnica de Grupo Nominal (TGN) original, permitindo sua aplicação ao formato virtual, preservando todos os seus elementos-chave. Método: Relato de experiência sobre as adaptações e adequações realizadas na TGN original ao formato virtual aplicando as Tecnologias da Informação e Comunicação (TIC), por meio de ferramentas digitais disponibilizadas gratuitamente ou de baixo custo e de fácil manejo. Resultados: A TGN foi realizada integralmente de forma virtual e sofreu adaptações em cada uma das suas quatro etapas através da incorporação de recursos digitais específicos. Foi possível apresentar as ideias mais votadas e obter a aprovação final dos participantes. Os participantes não apresentaram dificuldade para utilizar os recursos virtuais disponibilizados, e, partir da avaliação de reação, mostram-se satisfeitos com as ferramentas disponibilizadas. Conclusão: A TGN adaptada mostrou-se um método efetivo quando utilizada em cenário virtual, sendo capaz de produzir um significativo número de ideias e desenvolver consenso. A ferramenta adaptada pode ser usada por outros pesquisadores em países com recursos ou dimensões semelhantes ao Brasil. Objetivo (TGN elementoschave. elementoschave elementos chave. chave elementos-chave Método TIC, TIC , (TIC) manejo Resultados específicos disponibilizados reação mostramse mostram se Conclusão mostrouse mostrou consenso Brasil (TIC

https://doi.org/10.1590/1980-220x-reeusp-2023-0298en

10.

Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023 202 20 2
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Feitosa, Audes Diogenes de Magalhães

; Barroso, Weimar Kunz Sebba

; Mion Junior, Decio

; Nobre, Fernando

; Mota-Gomes, Marco Antonio

; Jardim, Paulo Cesar Brandão Veiga

; Amodeo, Celso

; Oliveira, Adriana Camargo

; Alessi, Alexandre

; Sousa, Ana Luiza Lima

; Brandão, Andréa Araujo

; Pio-Abreu, Andrea

; Sposito, Andrei C.

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Rodrigues, Cibele Isaac Saad

; Forjaz, Claudia Lucia de Moraes

; Sampaio, Diogo Pereira Santos

; Barbosa, Eduardo Costa Duarte

; Freitas, Elizabete Viana de

; Cestario, Elizabeth do Espirito Santo

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Feitosa, Fabiana Gomes Aragão Magalhães

; Consolim-Colombo, Fernanda Marciano

; Almeida, Fernando Antônio de

; Silva, Giovanio Vieira da

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Guimarães, Isabel Cristina Britto

; Gemelli, João Roberto

; Barreto-Filho, José Augusto Soares

; Vilela-Martin, José Fernando

; Ribeiro, José Marcio

; Yugar-Toledo, Juan Carlos

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano F.

; Bortolotto, Luiz Aparecido

; Alves, Marco Antonio de Melo

; Malachias, Marcus Vinícius Bolívar

; Neves, Mario Fritsch Toros

; Santos, Mayara Cedrim

; Dinamarco, Nelson

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Vitorino, Priscila Valverde de Oliveira

; Miranda, Roberto Dischinger

; Bezerra, Rodrigo

; Pedrosa, Rodrigo Pinto

; Paula, Rogerio Baumgratz de

; Okawa, Rogério Toshiro Passos

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C.

; Lima, Sandro Gonçalves de

; Inuzuka, Sayuri

; Ferreira-Filho, Sebastião Rodrigues

; Fillho, Silvio Hock de Paffer

; Jardim, Thiago de Souza Veiga

; Guimarães Neto, Vanildo da Silva

; Koch, Vera Hermina Kalika

; Gusmão, Waléria Dantas Pereira

; Oigman, Wille

; Nadruz Junior, Wilson

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 4 elocation e20240113

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20240113

11.

THE POWDER OF Co64Nb30B6 OBTAINED BY MECHANICAL ALLOYING CoNbB Co Nb B Co64Nb30B
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Nascimento, Luciano

; Morais, Ítallo Campos Gonçalves de

; Silva, Adriano Lima da

; Melo, João Baptista da Costa Agra de

; Guedes, Danyelle Garcia

; Araújo, Lincoln Rodrigues Sampaio de

; Silva, Suédina Maria de Lima

; Costa, Ana Cristina Figueiredo de Melo

Química Nova

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2024, Volume 47 N. 8 elocation e-20240030

Abstract: En | Text: En | PDF: En

This work aims to synthesize the alloy Co64Nb30B6 through mechanical alloying using a planetary ball mill. A disc rotation per minute and a ball/powder weight ratio of 300 rpm and 10:1 were used, with a milled time of 10 h, respectively. The characterization of the Co64Nb30B6 alloy was performed by X-ray diffraction (XRD), examined by scanning electron microscope-energy dispersive X-ray spectroscopy (SEM-EDS), thermoanalytical techniques (TGA/DTA), vibrating sample magnetometer (VSM) and confirmed by Braunauer, Emmet e Teller (BET) method type IV isotherms with a hysteresis loop for mesoporous materials. The results indicated that the evolution of the amorphous phase in the Co64Nb30B6 composition through the mechanical alloying process exhibited good soft magnetic properties with the addition of the metalloid element B and its excellent unique ferromagnetic properties. Through thermoanalytical analysis (TGA/DTA), it was shown that at higher temperatures, Co and Nb ions are oxidized by the environment and, therefore, the mass can be slightly increased to 14.9% and a probable contribution of boron in evolution stability thermal and magnetic in the amorphous phase, respectively. This suggests that the newly developed high-performance amorphous alloy Co64Nb30B6 has great application potential. CoNbB Co64Nb30B mill ballpowder powder 30 101 1 10: used h respectively Xray X ray XRD, XRD , (XRD) microscopeenergy microscope energy SEMEDS, SEMEDS SEM EDS (SEM-EDS) TGA/DTA, TGADTA TGA/DTA TGA DTA (TGA/DTA) VSM (VSM Braunauer BET (BET materials temperatures therefore 149 14 9 14.9 highperformance high performance potential 3 (XRD (SEM-EDS (TGA/DTA 14.

https://doi.org/10.21577/0100-4042.20240030

12.

Multiple myeloma and Chagas disease: qPCR as a marker for preemptive antiparasitic therapy: a case reports series and review disease therapy
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Carvalho, Noemia Barbosa

; Freitas, Vera Lúcia Teixeira de

; Seguro, Fernanda Salles

; Bezerra, Rita Cristina

; Fatobene, Giancarlo

; Nakanishi, Érika Yoshie Shimoda

; Visnadi, Helena

; Martinez, Gracia

; Batista, Marjorie Vieira

; Rocha, Vanderson

; Dulley, Frederico Luis

; Costa, Sílvia Figueiredo

; Shikanai-Yasuda, Maria Aparecida

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e10

Abstract: En | Text: En | PDF: En

ABSTRACT Multiple myeloma (MM) associated with Chagas disease is rarely described. This disease and its therapy suppress T cell and macrophage functions and increase regulatory T cell function, allowing the increase of parasitemia and the risk of Chagas Disease Reactivation (CDR). We aimed to analyze the role of conventional (cPCR) and quantitative Polymerase Chain Reaction (qPCR) for prospective monitoring of T. cruzi parasitemia, searching for markers of preemptive antiparasitic therapy in MM patients with Chagas disease. Moreover, we investigated the incidence and management of hematological diseases and CDR both inside and outside the transplant setting in the MEDLINE database. We found 293 studies and included 31 of them. Around 1.9–2.0% of patients with Chagas disease were reported in patients undergoing Stem Cell Transplantation. One case of CDR was described in eight cases of MM and Chagas disease. We monitored nine MM and Chagas disease patients, seven under Autologous Stem Cell Transplantation (ASCT), during 44.56±32.10 months (mean±SD) using parasitological methods, cPCR, and qPCR. From these patients, three had parasitemia. In the first, up to 256 par Eq/mL were detected, starting from 28 months after ASCT. The second patient dropped out and died soon after the detection of 161.0 par Eq/mL. The third patient had a positive blood culture. Benznidazole induced fast negativity in two cases; followed by notably lower levels in one of them. Increased T. cruzi parasitemia was related to the severity of the underlying disease. We recommend parasitemia monitoring by qPCR for early introduction of preemptive antiparasitic therapy to avoid CDR. (MM function . (CDR) cPCR (cPCR (qPCR Moreover database 29 3 them 1920 1 9 2 0 1.9–2.0 ASCT, ASCT , (ASCT) 44563210 44 56 32 10 44.56±32.1 mean±SD meanSD mean SD (mean±SD methods first 25 EqmL Eq mL detected 1610 161 161. culture (CDR 192 1.9–2. (ASCT 4456321 4 5 44.56±32. 16 19 1.9–2 445632 44.56±32 1.9– 44563 44.56±3 1.9 4456 44.56± 1. 445 44.56 44.5 44.

https://doi.org/10.1590/s1678-9946202466010

13.

Eveningness and preeclampsia in gestational diabetes – a response to the letter “Chronotype of pregnant women with diabetes mellitus: what is the relationship with maternal and fetal outcomes” Chronotype mellitus outcomes
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Facanha, Cristina Figueiredo Sampaio

; Alencar, Victória Sudário

; Machado, Paula Soares

; Macêdo, Rejane Belchior Lima

; de Bruin, Pedro Felipe Carvalhedo

; Costa e Forti, Adriana

; Rocha, Thaine Mirla

; de Bruin, Veralice Meireles Sales

Archives of Endocrinology and Metabolism

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2024, Volume 68 elocation e230141

Abstract: En | Text: En | PDF: En

https://doi.org/10.20945/2359-4292-2023-0141

14.

A spatial case-control study on symptomatic and inapparent primary dengue infections in an endemic city in Brazil casecontrol case control
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Figueiredo, Gerusa

; Chiaravalloti, Francisco

; Campos, Sérgio

; Pellini, Alessandra Cristina Guedes

; Felix, Alvina Clara

; Luna, Expedito

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e12

Abstract: En | Text: En | PDF: En

ABSTRACT We conducted a spatial case-control study nested in a dengue incidence cohort to explore the role of the spatial and socioeconomic factors in the proportion of symptomatic (cases) and inapparent primary dengue virus infections (controls). Cohort participants were children and adolescents (2 to 16 years of age) at the beginning of the follow-up. Case definitions were, for symptomatic cases, fever plus a positive lab result for acute dengue (NS1, RT-PCR, ELISA IgM/IgG), and for inapparent infection a positive result for dengue IgG (ELISA) in subjects without symptoms and with a previously negative result at baseline. The covariates included sociodemographic factors, residential location, and socioeconomic context variables of the census tracts of residence of cases and controls. We used principal component analysis to reduce the contextual covariates, with the component values assigned to each one based on their residences. The data were modeled in a Bayesian context, considering the spatial dependence. The final sample consisted of 692 children, 274 cases and 418 controls, from the first year of follow-up (2014-2015). Being male, older age, higher educational level of the head of the family and having a larger number of rooms in the household were associated with a greater chance of presenting dengue symptomatic infection at the individual level. The contextual covariates were not associated with the outcome. Inapparent dengue infection has extensive epidemiological consequences. Relying solely on notifications of symptomatic dengue infections underestimates the number of cases, preserves a silent source of the disease, potentially spreading the virus to unaffected areas. casecontrol case control (cases controls . (controls) 2 ( 1 age followup. followup follow up. up NS1, NS1 NS (NS1 RTPCR, RTPCR RT PCR, PCR RT-PCR IgM/IgG, IgMIgG IgM/IgG , IgM IgM/IgG) (ELISA baseline location residences dependence 69 27 41 20142015. 20142015 2014 2015 (2014-2015) male outcome consequences disease areas (controls (NS 6 4 2014201 201 (2014-2015 201420 20 (2014-201 20142 (2014-20 (2014-2 (2014- (2014 (201 (20

https://doi.org/10.1590/s1678-9946202466012

15.

Sequential extraction of anthocyanins and pectin from jabuticaba (Plinia cauliflora) peel: Peel pretreatment effect and ultrasound-assisted extraction Plinia cauliflora peel ultrasoundassisted ultrasound assisted
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BUENO, TAINAH M.

; QUEIROZ, FABIANA

; SANTOS, JHENIFER CRISTINA C. DOS

; FURTADO, MARIA LUIZA B.

; SCHIASSI, MARIA CECÍLIA E.V.

; BORGES, SORAIA V.

; FIGUEIREDO, JAYNE A.

Anais da Academia Brasileira de Ciências

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2024, Volume 96 N. 1 elocation e20230174

Abstract: En | Text: En | PDF: En

Abstract The jabuticaba bark is rich in anthocyanins and fibers, and its use may be of industrial interest. In the food sector, its used as an ingredient in the production of fermented products, liqueurs or enriched flours. It also has pharmaceutical and cosmetic applications. The objective was to evaluate the effect of pretreatment and fresh use of jabuticaba peels in the extraction of total phenolic compound (TPC) and total anthocyanin (TA) contents with and without ultrasound assistance and in the sequential extraction of pectin from the residue. In the TPC and TA extraction, a 3x2 factorial design was used. For conventional anthocyanin extraction (CAE), occurred in an incubator under agitation. For ultrasound-assisted anthocyanin extraction (UAE) was utilized an ultrasonic homogenizer with probe (20 kHz, 160 W). The extracts were quantified (TPC, TA, antioxidant activity and color). The residues were characterized and used for sequential pectin extraction, which was quantified and characterized. The results were subjected to analysis of variance. Fresh jabuticaba peel is a residue that can be used to sequentially extract phenolic compounds, particularly anthocyanins and pectin. The use of ultrasound (UAE) was less efficient than CAE for extracting TPC and TA or performing sequential extraction on all pretreatment peels. fibers interest sector products flours applications (TPC (TA x 3x CAE, , (CAE) agitation ultrasoundassisted assisted UAE (UAE 20 (2 kHz 16 W. W . W) TPC, color. color color) variance compounds (CAE 2 ( 1

https://doi.org/10.1590/0001-3765202420230174

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