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Análise de desempenho dos centros dialíticos no encaminhamento e inscrição em lista de espera pré-transplante renal em Minas Gerais, Brasil, 2015 a 2019
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Pereira, Cláudio Vitorino

; Leite, Isabel Cristina Gonçalves

; Nogueira, Mário Círio

; Ferreira, Gustavo Fernandes

Cadernos de Saúde Pública

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2025, Volume 41 N. 1 elocation e00021423

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

Abstract: Despite the relevance of kidney transplantation, the supply of organs and the process for inclusion in its waiting list still represent obstacles. This study aimed to analyze the performance of dialysis centers in referring patients for pre-kidney transplant evaluation and inclusion in the waiting list of incident dialysis patients from 2015 to 2019 in the state of Minas Gerais, Brazil. This retrospective cohort study sampled 23,297 records of patients who underwent dialysis therapy in public or philanthropic institutions or who had their treatment funded by the Brazilian Unified National Health System in private clinics. Survival analysis by the Kaplan-Meier method was used to evaluate pre-kidney transplant referral. The strength of the association between the exposure variables and the occurrence of inclusion on the list were analyzed by Cox regression models. Only 14.8% of the sample was enrolled on the pre-kidney transplant waiting list. The cumulative probability of enrollment totaled 1.2% in 180 days and 3.3% in one year from 2016 to 2019. Northern Minas Gerais had the highest cumulative probability of enrollment on the waiting list, whereas its South, the lowest. Adult individuals were more likely to be enrolled than older adults, and enrollment was more likely in 2016 than in 2018 and 2019. Although Ordinance n. 389/2014 from the Brazilian Ministry of Health established the minimum percentage of eligible patients that must be included in the list, this study observed no positive repercussion on the accumulated probability of enrollment in dialysis incidents in subsequent years.

Resumo: Apesar da relevância do transplante renal, a oferta de órgãos e o processo para inclusão na lista de espera ainda representam entraves. O presente estudo teve como objetivo analisar o desempenho dos centros dialíticos no encaminhamento para avaliação pré-transplante renal e inclusão em lista de espera de pacientes incidentes em diálise, no período de 2015 a 2019, no Estado de Minas Gerais, Brasil. Trata-se de um estudo de coorte retrospectivo, que teve como amostra 23.297 registros de pacientes que realizaram terapia dialítica em instituições públicas, filantrópicas ou que tiveram seu tratamento custeado pelo Sistema Único de Saúde em clínicas privadas conveniadas. Para avaliação do encaminhamento pré-transplante renal, realizou-se a análise de sobrevida pelo método Kaplan-Meier. A força da associação entre as variáveis de exposição e a ocorrência da inscrição na lista foram analisadas por meio dos modelos de regressão de Cox. Ao analisar a inscrição em lista de espera pré-transplante renal, 14,8% da amostra encontrava-se inscrita. A probabilidade acumulada de inscrição foi de 1,2% em 180 dias e 3,3% em um ano, entre 2016 e 2019. A macrorregião Norte apresentou maior probabilidade acumulada de inscrição em lista de espera, enquanto a Sul apresentou a menor. Assim como indivíduos adultos apresentaram maior probabilidade de inscrição em relação aos idosos, e o ano de 2016 obteve maior probabilidade em relação aos anos de 2018 e 2019. Embora estabelecido na Portaria nº 389/2014 do Ministério da Saúde o percentual mínimo de pacientes aptos que devem ser inseridos em lista, não foi observada repercussão positiva na probabilidade acumulada de inscrição entre os incidentes em diálise nos anos subsequentes.

Resumen: A pesar de la relevancia del trasplante renal, el suministro de órganos y el proceso de inclusión en la lista de espera siguen representando obstáculos. Este estudio tuvo como objetivo analizar el desempeño de los centros de diálisis en la derivación para evaluación renal previa al trasplante e inclusión en la lista de espera de pacientes incidentes en diálisis en el período de 2015 a 2019, en el estado de Minas Gerais, Brasil. Se trata de un estudio de cohorte retrospectivo con una muestra de 23.297 registros de pacientes que se sometieron a terapia de diálisis en instituciones públicas, filantrópicas o que tuvieron su tratamiento financiado por el Sistema Único de Salud en clínicas afiliadas privadas. Para evaluar la derivación previa al trasplante de riñón, se realizó un análisis de supervivencia utilizando el método de Kaplan-Meier. La fuerza de la asociación entre las variables de exposición y la ocurrencia de inscripción en la lista se analizaron utilizando modelos de regresión de Cox. Se encontró que un 14,8% de la muestra estaba inscrita en la lista de espera previa al trasplante de riñón. La probabilidad acumulada de inscripción fue del 1,2% en 180 días y del 3,3% en un año, entre 2016 y 2019. La macrorregión Norte presentó la mayor probabilidad acumulada de inscripción en lista de espera, mientras que la Sur presentó la más baja. Además, los individuos adultos tuvieron una mayor probabilidad de inscribirse en comparación con los ancianos, y 2016 tuvo una mayor probabilidad en comparación con 2018 y 2019. Aunque está determinado en la Ordenanza nº 389/2014 del Ministerio de Salud un porcentaje mínimo de pacientes elegibles que deben incluirse en la lista, no se encontró un impacto positivo en la probabilidad acumulada de inscripción en los incidentes de diálisis en los años posteriores.

https://doi.org/10.1590/0102-311xpt021423

Saturated hydraulic conductivity and steady-state infiltration rate database for Brazilian soils
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Ottoni, Marta Vasconcelos

; Teixeira, Wenceslau Geraldes

; Reis, Aline Mari Huf dos

; Pimentel, Letícia Guimarães

; Souza, Luciana Rodrigues

; Albuquerque, Jackson Adriano

; Melo, Valdinar Ferreira

; Cavalieri-Polizeli, Karina Maria Vieira

; Reichert, José Miguel

; Viana, João Herbert Moreira

; Fontana, Ademir

; Medrado, Lucas de Castro

; Santos, Glenio Guimarães

; Amaral, Luís Gustavo Henriques do

; Anjos, Lúcia Helena Cunha dos

; Araújo Filho, José Coelho de

; Bhering, Silvio Barge

; Brito, Gabrielle Fernandes de

; Valle, Pedro Gomes de Campos do

; Campos, Pablo Nieto

; Costa, Adriana Monteiro da

; Marques, Jean Dalmo de Oliveira

; Martins, Alba Leonor da Silva

; Nascimento, Michele Bruna de Souza do

; Noronha, Norberto Cornejo

; Oliveira, Ricardo Duarte de

; Portela, Jeane Cruz

; Serafim, Milson Evaldo

; Silva, Marlen Barros e

; Rodrigues, Sueli

; Almeida, Wilk Sampaio de

; Moraes, Margareth Lopes de

; Curi, Nilton

Revista Brasileira de Ciência do Solo

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2025, Volume 49 elocation e0240003

Abstract: En | Text: En | PDF: En

ABSTRACT Soil saturated hydraulic conductivity (Ksat) and steady-state infiltration rate (SSIR) are essential and necessary soil properties for different geoscience applications. Values of these hydraulic properties for the Brazilian territory are difficult to access and are dispersed in research efforts carried out around the country. This study developed an easy-to-manipulate, freely accessible database of soil saturated hydraulic conductivity, comprising field and laboratory analyses, and steady-state infiltration rates for Brazilian soils. This database was named Ksat-SSIR-DB. One analysis of the Ksat-SSIR-DB aimed to evaluate its coverage in Brazilian territory and in different soil groups. Average values of these hydraulic properties were also presented for textural classes, with values compared to those reported in international literature, and for other groupings, such as soil class, land use class, and porosity class. The variability of Ksat data in these groupings and in their combinations were also analyzed. The Ksat-SSIR-DB showed broad national coverage, comprising a total of 2,579 records, corresponding to 409 sampling sites, with Ksat and/or SSIR data and other associated soil information. A significant difference was observed between Ksat values for the vast majority of Brazilian clayey and very clayey soils compared to soils from the same textural groups from temperate regions. The two groupings that presented the lowest variability in terms of Ksat standard deviation values were the combination of textural classes with soil classes at the second category level of SiBCS (Brazilian Soil Classification System), and porosity classes with soil classes at the second category level of SiBCS. The Ksat-SSIR-DB has enormous potential for developing and testing Ksat pedotransfer functions in Brazilian soils, serving as a reference source for different geoenvironmental applications and, in particular, for modeling land surface processes. It is open access and can be accessed at https://www.sgb.gov.br/ksat-ssir-dbbase-de-dados-de-condutividade-hidraulica-saturada-e-de-taxa-de-infiltracao-basica-emsolos-brasileiros, which also includes the python script for data analysis.

https://doi.org/10.36783/18069657rbcs20240003

Ocorrência de Infecção do Trato Urinário em Pacientes após Transplante Renal
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Silva, Elisa Camila de Souza e

; Guilherme, Sibely de Paula

; Miranda, Cristina Nantes

; Alvim, André Luiz Silva

; Ferreira, Gustavo Fernandes

; Nascimento, Thiago Cesar

; Rocha, Ana Paula Machado da

Brazilian Journal of Transplantation

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2025, Volume 28 elocation e0425

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Introduction: The Brazilian Society of Nephrology estimates that approximately 10 million people in Brazil had chronic kidney disease in 2019. In 2022, 5,303 kidney transplants were performed in the country, with the city of Juiz de Fora standing out as one of the largest reference centers for kidney transplants. Objectives: The objective of this study is to evaluate the occurrence of urinary tract infections in post-transplant patients, as well as the type of infection. Methods: This is a retrospective quantitative cross-sectional study in which data from the medical records of patients who underwent kidney transplantation from 2019 to 2022 were analyzed. Results: Of a total of 537 kidney transplants performed during this period, 64 urinary tract infections associated with urinary catheters were observed in the first 30 days post-transplantation, with a higher incidence in the first 5 days. Most of the microorganisms observed belong to the human microbiota, indicating that the cause may be related to catheterization, the hospital environment, or the patient. The infections observed are caused by bacteria resistant to the antibiotics trimethoprim and sulfamethoxazole, such as Escherichia coli, Klebsiella sp., and Serratia sp. Conclusion: The study indicates that it is necessary to improve the handling of the patients and materials to reduce infections, mainly due to the high degree of antibiotic resistance of the microorganisms observed.

RESUMO Introdução: A Sociedade Brasileira de Nefrologia estimou que cerca de 10 milhões de pessoas no Brasil tinham doença renal crônica em 2019. Em 2022, 5.303 transplantes renais foram realizados no país, destacando-se o município de Juiz de Fora como um dos maiores centros de referência em transplantes renais. Objetivos: O objetivo deste trabalho é avaliar a ocorrência de infecções no trato urinário de pacientes pós-transplante, bem como o tipo de infecção. Métodos: Trata-se de estudo transversal, quantitativo e retrospectivo, no qual dados dos prontuários dos pacientes que realizaram transplante renal de 2019 a 2022 foram analisados. Resultados: Do total de 537 transplantes renais realizados nesse período, foram observadas 64 infecções do trato urinário associadas ao cateter vesical nos primeiros 30 dias pós-transplante, com maior incidência nos primeiros 5 dias. A maior parte dos microrganismos observados pertence à microbiota humana, indicando que a causa pode estar relacionada ao cateterismo, ao ambiente hospitalar ou ao próprio paciente. As infecções são causadas por bactérias resistentes aos antibióticos trimetoprima e sulfametoxazol, como Escherichia coli, Klebsiella sp. e Serratia sp. Conclusão: O trabalho aponta que é necessário melhorar a manipulação dos pacientes e materiais, visando reduzir as infecções, principalmente em função do alto grau de resistência a antibióticos dos microrganismos observados.

https://doi.org/10.53855/bjt.v28i1.649_port

Análise de desempenho dos centros dialíticos no encaminhamento e inscrição em lista de espera pré-transplante renal em Minas Gerais, Brasil, 2015 a 2019
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Pereira, Cláudio Vitorino

; Leite, Isabel Cristina Gonçalves

; Nogueira, Mário Círio

; Ferreira, Gustavo Fernandes

Cadernos de Saúde Pública

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2025, Volume 41 N. 1 elocation e00021423

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/0102-311xpt021423

Spatial analysis of care for patients undergoing dialysis therapy in the state of Minas Gerais, Brazil, between 2015 and 2019
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Pereira, Claudio Vitorino

; Leite, Isabel Cristina Gonçalves

; Nogueira, Mário Círio

; Ferreira, Gustavo Fernandes

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240002

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar o fluxo espacial da assistência de pacientes em terapia dialítica nas regionais de saúde do estado de Minas Gerais. Métodos: Estudo ecológico que teve como população pacientes incidentes em terapia dialítica em instituições públicas, filantrópicas ou que tiveram seu tratamento custeado pelo Sistema Único de Saúde em clínicas privadas conveniadas, no estado de Minas Gerais. Os pacientes foram agregados por regional de saúde de residência. Foram calculadas as proporções de pacientes que fizeram diálise, bem como a inscrição na lista de transplante renal em sua própria região de residência ou fora dela. Estimadas as correlações de Person destas proporções com indicadores socioeconômicos e assistenciais das regionais de saúde. Técnicas exploratórias espaciais estimaram coeficientes de correlação espacial geral (I de Moran) e local (LISA). Resultados: Regiões com maior PIB apresentaram maior razão de nefrologistas e maior proporção de inscrições na própria região de residência. Identificou-se um cluster de regiões com PIB baixo mais ao nordeste do estado (também com valores mais baixos de razão de nefrologistas), um cluster de alta proporção de inscritos na lista de transplante no centro do estado, e um cluster de baixa proporção de diálise na mesma região de residência mais ao sudeste. Conclusão: Evidenciou-se disparidades regionais em relação à proporção de inscritos na lista de espera para o transplante renal, proporção de pacientes que realizavam diálise na mesma região de residência e proporção de pacientes inscritos na lista de espera para o transplante renal na mesma região de residência.

ABSTRACT Objective: To analyze the spatial flow of care for patients undergoing dialysis therapy in the health regions of the State of Minas Gerais. Methods: Ecological study whose population was patients undergoing dialysis therapy in public, philanthropic institutions or whose treatment was paid for by the Unified Health System in private clinics in partnership, in the State of Minas Gerais. Patients were grouped by health region of residence. The proportions of patients who underwent dialysis were calculated, as well as enrollment on the kidney transplant list in their own region of residence or outside it. Person correlations of these proportions with socioeconomic and care indicators of the health regions were estimated. Spatial exploratory techniques estimated general (Moran’s I) and local (LISA) spatial correlation coefficients. Results: Regions with higher GDP had a higher number of nephrologists and a higher proportion of registrations in the region of residence. A cluster of regions with low GDP was identified further to the northeast of the State (also with lower nephrologist ratio values), a cluster with a high proportion of those registered on the transplant list in the center of the State, and a cluster with a low proportion of dialysis in the same region of residence further southeast. Conclusion: Regional disparities were evident in relation to the proportion of patients registered on the waiting list for kidney transplantation, the proportion of patients undergoing dialysis in the same region of residence and the proportion of patients registered on the waiting list for kidney transplantation in the same region of residence. residence.

https://doi.org/10.1590/1980-549720240002

Impact of streptozotocin-induced diabetes on experimental masseter pain in rats
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COSTA, Yuri Martins

; HERCULIANI, Clarissa Carolina Fernandes

; SOARES, Flávia Fonseca Carvalho

; AZEVEDO, Michelle de Campos Soriani

; CONTI, Paulo César Rodrigues

; DIONÍSIO, Thiago José

; OLIVEIRA, Gabriela de Moraes

; FARIA, Flávio Augusto Cardoso de

; SANTOS, Carlos Ferreira

; GARLET, Gustavo Pompermaier

; BONJARDIM, Leonardo Rigoldi

Brazilian Oral Research

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2024, Volume 38 elocation e073

Abstract: En | Text: En | PDF: En

Abstract This study aimed to assess the influence of streptozotocin (STZ)-induced diabetes on the nociceptive behavior evoked by the injection of hypertonic saline (HS) into the masseter muscle of rats. Forty male rats were equally divided into four groups: a) isotonic saline control, which received 0.9% isotonic saline (IS), (Ctrl-IS); b) hypertonic saline control, which received 5% HS (Ctrl-HS); c) STZ-induced diabetic, which received IS, (STZ-IS); d) STZ-induced diabetic, which received HS (STZ-HS). Experimental diabetes was induced by a single intraperitoneal injection of STZ at dose of 60 mg/kg dissolved in 0.1 M citrate buffer, and 100 μL of HS or IS were injected into the left masseter to measure the nociceptive behavior. Later on, muscle RNA was extracted to measure the relative expression of the following cytokines: cyclooxygenase-2 (COX-2), tumor necrosis factor (TNF-α), and interleukins (IL)-1β, -2, -6, and -10. One-way analysis of variance (ANOVA) was applied to the data (p < 0.050). We observed a main effect of group on the nociceptive response (ANOVA: F = 11.60, p < 0.001), where the Ctrl-HS group presented the highest response (p < 0.001). However, nociceptive response was similar among the Ctrl-IS, STZ-IS, and STZ-HS group (p > 0.050). In addition, the highest relative gene expression of TNF-α and IL-6 was found in the masseter of control rats following experimental muscle pain (p < 0.050). In conclusion, the loss of somatosensory function can be observed in deep orofacial tissues of STZ-induced diabetic rats.

https://doi.org/10.1590/1807-3107bor-2024.vol38.0073

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024
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Fernandes, Fabio

; Simões, Marcus V.

; Correia, Edileide de Barros

; Marcondes-Braga, Fabiana Goulart

; Coelho-Filho, Otavio Rizzi

; Mesquita, Cláudio Tinoco

; Mathias Junior, Wilson

; Antunes, Murillo de Oliveira

; Arteaga-Fernández, Edmundo

; Rochitte, Carlos Eduardo

; Ramires, Felix José Alvarez

; Alves, Silvia Marinho Martins

; Montera, Marcelo Westerlund

; Lopes, Renato Delascio

; Oliveira Junior, Mucio Tavares de

; Scolari, Fernando Luis

; Avila, Walkiria Samuel

; Canesin, Manoel Fernandes

; Bocchi, Edimar Alcides

; Bacal, Fernando

; Moura, Lidia Zytynski

; Saad, Eduardo Benchimol

; Scanavacca, Mauricio Ibrahim

; Valdigem, Bruno Pereira

; Cano, Manuel Nicolas

; Abizaid, Alexandre Antonio Cunha

; Ribeiro, Henrique Barbosa

; Lemos Neto, Pedro Alves

; Ribeiro, Gustavo Calado de Aguiar

; Jatene, Fabio Biscegli

; Dias, Ricardo Ribeiro

; Beck-da-Silva, Luis

; Rohde, Luis Eduardo Paim

; Bittencourt, Marcelo Imbroinise

; Pereira, Alexandre da Costa

; Krieger, José Eduardo

; Villacorta Junior, Humberto

; Martins, Wolney de Andrade

; Figueiredo Neto, José Albuquerque de

; Cardoso, Juliano Novaes

; Pastore, Carlos Alberto

; Jatene, Ieda Biscegli

; Tanaka, Ana Cristina Sayuri

; Hotta, Viviane Tiemi

; Romano, Minna Moreira Dias

; Albuquerque, Denilson Campos de

; Mourilhe-Rocha, Ricardo

; Hajjar, Ludhmila Abrahão

; Brito Junior, Fabio Sandoli de

; Caramelli, Bruno

; Calderaro, Daniela

; Farsky, Pedro Silvio

; Colafranceschi, Alexandre Siciliano

; Pinto, Ibraim Masciarelli Francisco

; Vieira, Marcelo Luiz Campos

; Danzmann, Luiz Claudio

; Barberato, Silvio Henrique

; Mady, Charles

; Martinelli Filho, Martino

; Torbey, Ana Flavia Malheiros

; Schwartzmann, Pedro Vellosa

; Macedo, Ariane Vieira Scarlatelli

; Ferreira, Silvia Moreira Ayub

; Schmidt, Andre

; Melo, Marcelo Dantas Tavares de

; Lima Filho, Moysés Oliveira

; Sposito, Andrei C.

; Brito, Flávio de Souza

; Biolo, Andreia

; Madrini Junior, Vagner

; Rizk, Stephanie Itala

; Mesquita, Evandro Tinoco

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 7 elocation e202400415

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20240415

EARLY SELECTION OF EUCALYPTUS HYBRIDS TOLERANT TO WATER DEFICIT, PESTS, AND DISEASES
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Baesso, Gustavo

; Paixão, Camila Ferreira

; Santos, Gleison Augusto dos

; Souza, Genaina Aparecida de

; Canal, Guilherme Bravim

; Pimenta, Thaline Martins

; Caiafa, Karine Fernandes

; Lorenzoni, André Peixoto

Revista Árvore

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2024, Volume 48 elocation e4818

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo desse trabalho foi realizar a seleção precoce das melhores progênies para as características de tolerância ao déficit hídrico, a pragas e doenças, em testes de progênies de Eucalyptus. Os ensaios experimentais foram instalados em delineamento de blocos casualizados, com uma planta por parcela, com 20 repetições em três locais distintos (Buritizeiro/MG, Bocaiúva/MG e Inhambupe/BA). Aos 6 meses de idade, as famílias em teste foram avaliadas quanto ao incremento médio anual (IMA) e tolerância a pragas e doenças. As análises foram realizadas com base no procedimento genético-estatístico de modelos mistos via REML/BLUP. O processo seletivo baseou-se nos valores genéticos preditos para as famílias associando as duas características em analises através do uso de índices de seleção, sendo eles: os índices de seleção Multiplicativos e o índice de seleção de Mulamba e Mock, que permitiram a seleção simultânea para as características de produtividade (IMA) e tolerância à agentes bióticos. Em Buritizeiro/ MG, Bocaiúva/MG foi avaliada a tolerância das plantas à incidência de psilídio de concha (Glycaspis brimblecombei), e em Inhambupe/ BA foi avaliado à tolerância à ferrugem do eucalipto (Austropuccinia psidii). Para o caráter de tolerância a agentes bióticos, as herdabilidades (hg2) foram medianas nos três sites, apresentando valores de 0,20, 0,26 e 0,24 em Buritizeiro, Bocaiúva e Inhambupe, respectivamente. O uso dos índices Multiplicativo (IM) e de Mulamba e Mock (IMM) possibilitaram a seleção de materiais genéticos com melhor desempenho para as duas características de forma simultânea.

ABSTRACT The objective of this study was to perform early selection of the best progenies for traits related to tolerance to water deficit, pests, and diseases in Eucalyptus progeny tests. The experimental trials were set up in a randomized block design, with one plant per plot, and 20 replicates across three distinct locations (Buritizeiro/MG, Bocaiúva/MG, and Inhambupe/BA). At 6 months of age, the tested families were evaluated in terms of mean annual increment (MAI) and tolerance to pests and diseases. The analyses were conducted based on the genetic-statistics procedure of mixed models via REML/BLUP. The selection process was based on the estimated genetic values for the families, associating both traits in analyses using selection indices, namely the Multiplicative Selection Index and the Mulamba and Mock Selection Index, which allowed simultaneous selection for productivity (MAI) and tolerance to biotic agents. In Buritizeiro/MG and Bocaiúva/MG, plant tolerance to the psyllid (Glycaspis brimblecombei) was evaluated, while in Inhambupe/BA, tolerance to eucalyptus rust (Austropuccinia psidii) was assessed. For the trait of tolerance to biotic agents, heritabilities (hg2) were moderate across the three sites, with values of 0.20, 0.26, and 0.24 in Buritizeiro, Bocaiúva, and Inhambupe, respectively. The use of the Multiplicative Index (MI) and Mulamba and Mock Index (MMI) enabled the selection of genetic materials with better performance for both traits simultaneously.

https://doi.org/10.53661/1806-9088202448263765

Spatial analysis of care for patients undergoing dialysis therapy in the state of Minas Gerais, Brazil, between 2015 and 2019
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Pereira, Claudio Vitorino

; Leite, Isabel Cristina Gonçalves

; Nogueira, Mário Círio

; Ferreira, Gustavo Fernandes

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240002

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1980-549720240002

10.

Roteiros experimentais imagéticos: contribuições semióticas sobre o ensino de reações químicas para alunos surdos
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Ferreira, Leonardo Matos

; Rodrigues, Gustavo Fernandes

; Pereira, Lidiane de Lemos Soares

; Benite, Claudio Roberto Machado

Revista Brasileira de Estudos Pedagógicos

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2024, Volume 105 elocation e6008

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: O estudo se propõe a analisar, à luz da semiótica peirceana, a compreensão conceitual sobre as reações químicas e as diferentes evidências que comprovam suas ocorrências, com base na realização de experimentos orientados por roteiros imagéticos contendo procedimentos experimentais descritos com recursos visuais. A investigação com elementos da pesquisa participante foi desenvolvida em um centro educacional bilíngue de surdos e contou com a participação de nove alunos da 2ª série do ensino médio, a professora regente, um professor em formação inicial e um em formação continuada. Os dados consistiram na transcrição das interações discursivas coletadas por meio da videogravação e foram submetidos à análise da conversação. Os resultados demonstram que os alunos surdos conseguem executar autonomamente os experimentos por meio do roteiro imagético e evidenciam a manifestação dos conceitos peirceanos de primeiridade, secundidade e terceiridade durante a realização da intervenção pedagógica, o que comprova a potencialidade do uso do roteiro experimental imagético para a elaboração conceitual dos alunos surdos.

Abstract: The study proposes to analyze, in light of Peircean semiotics, the conceptual comprehension of chemical reactions and the different evidence that proves their occurrence, by carrying out experiments guided by imagery scripts containing experimental procedures described with visual resources. Our investigation employs elements of participatory research and was developed in a bilingual educational center for the deaf, while the participants were nine second-year high school students, the head teacher, a teacher in initial training and another in continuing training. Data consisted of the transcription of discursive interactions collected from video recordings, which were subjected to conversation analysis. Our results demonstrate that deaf students are able to autonomously execute experiments based on the imagery script, illustrating the manifestation of Peirce's concepts of firstness, secondness and thirdness during pedagogical intervention, ultimately proving the potential of using imagery experimental scripts for the conceptual elaboration of deaf students.

Resumen: El estudio propone analizar, a la luz de la semiótica peirceana, la comprensión conceptual de las reacciones químicas y las diferentes evidencias que prueban sus ocurrencias, a partir de la realización de experimentos orientados por guiones de imágenes que contienen procedimientos experimentales descritos con recursos visuales. La búsqueda con elementos de investigación participativa se desarrolló en un centro educativo bilingüe para sordos y contó con la participación de nueve estudiantes de segundo año de secundaria, la profesora titular, un docente en formación inicial y otro en formación continua. Los datos consistieron en la transcripción de interacciones discursivas recopiladas mediante grabación de vídeo y fueron sometidas a análisis de conversación. Los resultados indican que los estudiantes sordos son capaces de llevar a cabo experimentos basados en el guion de imágenes y demuestran la manifestación de los conceptos peirceanos de primeridad, segundidad y terceridad durante la intervención pedagógica, concluyendo el potencial del uso del guion experimental de imágenes para la elaboración conceptual de los estudiantes sordos.

https://doi.org/10.24109/2176-6681.rbep.105.6008

11.

Importância e Relevância do Brazilian Journal of Transplantation para a Transplantação Brasileira
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Boin, Ilka de Fatima Santana Ferreira

; Haddad, Luciana

; Ferreira, Gustavo Fernandes

Brazilian Journal of Transplantation

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2024, Volume 27 elocation e0624

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O Brazilian Journal of Transplantation, por meio de sua atuação e comprometimento com altos padrões éticos e acadêmicos, almeja consolidar-se como uma referência na disseminação de conhecimento e avanço científico no campo dos transplantes, tanto nacional quanto internacionalmente. É inegável a contribuição social da BJT como um veículo de divulgação confiável e avaliado por pares. Alcança não apenas a comunidade científica, mas também a população em geral, desmistificando os processos de doação de órgãos, evidenciando o modelo de distribuição dos órgãos por meio da fila única nacional e sensibilizando para a necessidade da doação.

ABSTRACT The Brazilian Journal of Transplantation, through its activities and commitment to high ethical and academic standards, aims to consolidate itself as a reference in the dissemination of knowledge and scientific advancement in the field of transplants, both nationally and internationally. BJT's social contribution as a reliable and peer-reviewed dissemination vehicle is undeniable. It reaches the scientific community and the population in general, demystifying the organ donation processes, highlighting the organ distribution model through the national single queue and raising awareness of the need for donation.

https://doi.org/10.53855//bjt.v27i1.555_port

12.

Posicionamento Brasileiro sobre Síndrome da Quilomicronemia Familiar – 2023 202 20 2
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Izar, Maria Cristina de Oliveira

; Santos Filho, Raul Dias dos

; Assad, Marcelo Heitor Vieira

; Chagas, Antonio Carlos Palandri

; Toledo Júnior, Alceu de Oliveira

; Nogueira, Ana Cláudia Cavalcante

; Souto, Ana Cristina Carneiro Fernandes

; Lottenberg, Ana Maria

; Chacra, Ana Paula Marte

; Ferreira, Carlos Eduardo dos Santos

; Lourenço, Charles Marques

; Valerio, Cynthia Melissa

; Cintra, Dennys Esper

; Fonseca, Francisco Antonio Helfenstein

; Campana, Gustavo Aguiar

; Bianco, Henrique Tria

; Lima, Josivan Gomes de

; Castelo, Maria Helane Costa Gurgel

; Scartezini, Marileia

; Moretti, Miguel Antonio

; Barreto, Natasha Slhessarenko Fraife

; Maia, Rayana Elias

; Montenegro Junior, Renan Magalhães

; Alves, Renato Jorge

; Figueiredo, Roberta Marcondes Machado

; Fock, Rodrigo Ambrosio Martinez, Tânia Leme da Rocha Giraldez, Viviane Zorzanelli Rocha

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 N. 4 elocation e20230203

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20230203

13.

Donor-derived TB after kidney transplantation: a case report
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Ulisses, Luiz Roberto de Sousa

; Cardoso, Helen Souto Siqueira

; Alves, Inara Creão Costa

; Medeiros, Isabela Novais

; Oliveira, Camilla Garcia de

; Almeida, Tiago Martins de

; Castro, Fabíola Fernandes dos Santos

; Silva, Claudia Neto Gonçalves Neves da

; Lima, Laura Viana de

; Fontoura, Renata Pereira

; Silva, Eduardo Resende Sousa e Araújo, Pollyana Lopes de Ferreira, Gustavo de Sousa Arantes

Brazilian Journal of Nephrology

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mar 2022, Volume 44 N. 1 Pages 126 - 129

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A tuberculose (TB) é uma possível complicação grave do transplante de órgãos sólidos, associada à alta mortalidade e morbidade. A TB pós-transplante tem patogênese variada com muitas abordagens para sua prevenção, que é a forma mais importante de reduzir sua incidência. O tratamento da TB em receptores de órgãos é um desafio devido à toxicidade dos medicamentos e à interação com imunossupressores. Relato de caso: uma mulher de 18 anos que foi submetida a transplante renal de um doador falecido e recebeu alta com função renal adequada foi readmitida no 37º dia de pós-operatório com febre. A TC mostrou sinais de TB miliar e coleção de fluidos além de fistulização do enxerto através da pele. A paciente apresentou BAAR positivo no fluido drenado e bacilo de Koch na urina. Ela foi tratada com um esquema de quatro medicamentos (rifampicina, isoniazida, pirazinamida e etambutol), com ótima resposta e função de enxerto preservada. Fomos informados de que o receptor do rim contralateral também apresentou TB pós-transplante, implicando em uma origem derivada do doador. Conclusão: A TB é um importante diagnóstico diferencial para complicações infecciosas em pacientes após transplante de órgãos sólidos, especialmente em regiões endêmicas. Sua apresentação clínica inicial pode não ser específica e deve ser suspeitada na presença de febre ou formação de coleções de fluidos. A suspeita de TB é a chave para o diagnóstico precoce e desfechos satisfatórios na TB pós-transplante.

Abstract Introduction: Tuberculosis (TB) is a possible serious complication of solid organ transplantation, associated with high mortality and morbidity. Post-transplant TB has varied pathogenesis with many approaches to its prevention, which is the most important way to reduce its incidence. Treatment of TB in organ recipients is challenging because of drug toxicity and interaction with immunosuppressants. Case report: an 18-year-old woman that underwent kidney transplantation from a deceased donor and was discharged with fair renal function was readmitted at 37th postoperative day with fever. CT showed signs of miliary TB and fluid collection besides graft fistulization through the skin. The patient presented positive BAAR in the drained fluid and Koch's bacillus in the urine. She was treated with a four-drug regimen (rifampicin, isoniazid, pyrazinamide, and etambutol), with great response and preserved graft function. We were informed that the recipient of the contralateral kidney also presented post-transplant TB, implying in a donor-derived origin. Conclusion: TB is an important differential diagnosis for infectious complications in patients after solid-organ transplantation, especially in endemic regions. Its initial clinical presentation can be unspecific and it should be suspected in the presence of fever or formation of fluid collections. The suspicion of TB is the key to early diagnosis and satisfactory outcomes in post-transplant TB.

https://doi.org/10.1590/2175-8239-jbn-2020-0117

14.

National Brazilian survey on the outcomes of hepatitis c retreatment in patients non-responders to direct antiviral agents
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Ferraz, Maria Lúcia Gomes

; Piccoli, Leonora de Zorzi

; Rezende, Rosamar

; Borba, Luiz Augusto

; Pissaia Junior, Alcindo

; Cheinquer, Hugo

; Silva, Giovanni Faria

; Ferreira, Paulo Roberto Abrão Villela-Nogueira, Cristiane Alves Mazo, Daniel Ferraz Souza, Fernanda Fernandes Codes, Liana Ivantes, Claudia Alexandra Pontes Gomide, Geisa Perez Medina Pereira, Gustavo Henrique Santos Pessôa, Mário Guimarães França, Alex Vianey Callado Pinto, Arlene dos Santos Teixeira, Rosângela Bittencourt, Paulo Lisboa

Brazilian Journal of Infectious Diseases

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2022, Volume 26 N. 4 elocation 102388

Abstract: En | Text: En | PDF: En

ABSTRACT Background and aims: Treatment of hepatitis C with direct antiviral agents (DAA) is associated with almost 95% of sustained virological response. However, some patients need retreatment. In Brazil, it should be done according to the Ministry of Health guidelines, frequently updated to include newly available drugs. This study aimed to conduct a national survey about the characteristics and outcomes of retreatment of hepatitis C in previously non-responders to DAAs. Patients and methods: Institutions from all over the country were invited to participate in a national registry for retreatment, including information about clinical and epidemiological characteristics of the patients, type and outcomes of retreatment regimens. Only patients previously treated with interferon-free regimens were included. Results: As previous treatments the distribution was: SOF/DCV (56%), SOF/SIM (22%), 3D (11%), SOF/LED (6%) and SOF/RBV (5%). For retreatment the most frequently used drugs were SOF/GP (46%), SOF/DCV (23%) and SOF/VEL (11%). From 159 patients retreated, 132/159 (83%) had complete information in the registry and among them only seven patients were non-responders (SVR of 94.6%). All retreatments were well tolerated, without any serious adverse events or interruptions. Conclusion: The retreatment of patients previously non-responders to DAAs was associated with high rate of SVR in this sample of Brazilian patients. This finding allows us to conclude that the retreatment options available in the public health system in Brazil are effective and safe and are an important component of the strategy of elimination of hepatitis C in our country.

https://doi.org/10.1016/j.bjid.2022.102388

15.

Calcium and Boron Foliar Application in the Production and Quality of Zucchini Seeds
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Colombari, Lidiane Fernandes

; Silva, Gustavo Ferreira da

; Chamma, Larissa

; Chaves, Prínscilla Pâmela Nunes

; Makita, Miguel Kenzo

; Soman, José Marcelo

; Cardoso, Antonio Ismael Inácio

Brazilian Archives of Biology and Technology

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2022, Volume 65 elocation e22220056

Abstract: En | Text: En | PDF: En

Abstract Although there are fertilization recommendations for the cultivation of zucchini, there are just few researches about the effects of nutrients in seed production. Calcium and boron have a low mobility in plants, and some researches recommend foliar application for these nutrients. Thus, the objective of this research was to evaluate the foliar application of calcium and boron in the production and quality of zucchini seeds. The experimental design was randomized blocks with seven replications. Four treatments were evaluated: only calcium (0.2%) application, only boron (0.1%) application, combined application of calcium (0.2%) and boron (0.1%) and the control (without calcium and boron.) The following characteristics were evaluated: number of pollen grains per flower, hundred seeds weight; seed number and weight per fruit and seed physiological quality (germination; first germination count and speed of germination index - SGI). Only boron application reduced the number of seeds produced per fruit. The combined foliar application of calcium and boron, in addition to reducing the number of seeds, also reduced SGI. The calcium only application increased the amount of pollen per flower (superior to all other treatments) and also the number of seeds per fruit (compared to the combined application of calcium + boron), without affecting the quality of the zucchini seeds. So, it can be recomended the aplication of Ca during zucchini flowering for seed production.

https://doi.org/10.1590/1678-4324-2022220056

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