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ABSTRACT BACKGROUND: Frailty is consensually understood to be a clinical syndrome in which minimal stressors can lead to negative outcomes such as hospitalization, early institutionalization, falls, functional loss and death. Frailty is more prevalent among patients with chronic kidney disease (CKD), and those on dialysis are the frailest. Depression contributes towards putting patients with CKD into the frailty cycle. OBJECTIVE: To assess frailty and its relationship with depression among patients with CKD undergoing hemodialysis. DESIGN AND SETTING: Observational and quantitative cross-sectional study conducted in a renal therapy unit, located in the interior of the state of São Paulo, Brazil. METHODS: This investigation took place in 2019, among 80 patients. The following instruments were applied: a sociodemographic, economic and health condition characterization and the Subjective Frailty Assessment (SFA) and Patient Health Questionnaire-9 (PHQ-9). RESULTS: Among the patients, there was higher prevalence of females, individuals with a steady partner and retirees, and their mean age was 59.63 (± 15.14) years. There was high prevalence of physical frailty (73.8%) and depression (93.7%). Depression was associated with frailty, such that patients with depression were 9.8 times more likely to be frail than were patients without depression (odds ratio, OR = 9.80; 95% confidence interval, CI, 1.93-49.79). CONCLUSION: Based on the proposed objective and the results achieved, it can be concluded that depression was associated with the presence of frailty among patients with CKD on hemodialysis.

https://doi.org/10.1590/1516-3180.2021.0556.r1.14092021

Relationship between levels of mindfulness and substance use pattern
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Baptista, Júlia de Souza

; Leite, Tatiana Henriques

; Ferreira, Vanessa Karam de Lima

; Magalhães, Luciana de Souza Pereira de

; Cruz, Marcelo Santos

; Mathias, Ana Carolina Robbe

Jornal Brasileiro de Psiquiatria

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mar 2022, Volume 71 N. 1 Pages 16 - 23

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective Evaluate the association between levels of mindfulness and sociodemographic characteristics and pattern of drug use of individuals seeking treatment in a University Service Specialized in Substance Use Disorders. Methods This is a cross-sectional study with 164 individuals over 18 years of age seeking treatment for the use of psychoactive substances in the June 2018-December 2019 period, using a questionnaire for sociodemographic data, the Mindful Attention Awareness Scale (MAAS) self-reporting instrument, and the Alcohol, Smoking, and Substance Involvement Screening Test. Results An association was found between low levels of mindfulness mainly with the individual risk of being a medium/high-risk user of sedative-hypnotic drugs (p = 0.020). A borderline association was also found between MAAS and the risk of the individual being a medium/high risk of alcohol (p = 0.053) and with a more severe pattern of substance use (p = 0.065). Conclusion Individuals seeking treatment for substance use presented impairments in the attentional aspect of mindfulness and levels of mindfulness seem to protect against behaviors related to substance use, especially against the use of high/moderate risk of sedative-hypnotics.

RESUMO Objetivo Avaliar a associação entre níveis de mindfulness e características sociodemográficas e padrão do uso de drogas de indivíduos que buscam tratamento em Serviço Universitário Especializado em Transtorno por Uso de Substâncias. Métodos Estudo de corte transversal de 164 indivíduos acima de 18 anos que buscavam tratamento para uso de substâncias psicoativas no período de junho de 2018 a dezembro de 2019, utilizando questionário para dados sociodemográficos, o instrumento de autorrelato Mindful Attention Awareness Scale (MAAS) e o Alcohol, Smoking and Substance Involvement Screening Test . Resultados Foi encontrada associação entre baixos níveis de mindfulness principalmente com o risco de o indivíduo ser usuário de médio/alto risco de sedativos-hipnóticos (p = 0,020). Também foi encontrada associação limítrofe entre MAAS com risco de o indivíduo ser usuário de médio/alto risco de álcool (p = 0,053) e com padrão mais grave de uso de substâncias (p = 0,065). Conclusão Indivíduos que buscavam tratamento para uso de substâncias apresentaram prejuízos no aspecto atencional de mindfulness , e níveis de mindfulness parecem proteger contra comportamentos relacionados ao uso de substâncias, principalmente contra o uso de alto/moderado risco de sedativos-hipnóticos.

https://doi.org/10.1590/0047-2085000000337

Association between frailty and depression among hemodialysis patients: a cross-sectional study
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Santos, Diana Gabriela Mendes dos

; Ferreira, Layana Giselly Silva

; Pallone, Joice Marques

; Ottaviani, Ana Carolina

; Santos-Orlandi, Ariene Angelini

; Pavarini, Sofia Cristina Iost

; Zazzetta, Marisa Silvana

; Orlandi, Fabiana de Souza

Sao Paulo Medical Journal

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2022, N. ahead

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1516-3180.2021.0556.r1.14092021

SILVICULTURAL TASKS SCHEDULING OPTIMIZATION: A CASE STUDY OF FUNCTIONS AND METHODS
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Mendonça, Nathalia de Paiva

; Lopes, Isáira Leite e

; Gomes, Vanessa de Souza

; Ferreira, Matheus Andrade

; Cruz, Bruno Rogério

; Silva, Carolina Souza Jarochinski e

; Gomide, Lucas Rezende

Revista Árvore

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2022, Volume 46 elocation e4602

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Scheduling problems are tasks of the operational routine in companies, which demand an optimal solution to support the decision. However, these problems have not been frequently investigated in forestry science. Therefore, it was proposed to describe a mathematical formulation for silviculture optimization under scheduling restriction of the workforce /sequencing of tasks (SSRCMM). Seeking the most suitable method to solve this combinatorial problem, two strategies were compared: i) Integer Linear Programming (ILP) and ii) simulated annealing (SA). The main criteria to assess strategies’ performance were to provide feasible solutions at an acceptable processing time and final project cost. The instance approached is a real problem outlined in 32 stands and five silvicultural tasks scheduled within a 40-day deadline. Three objective functions were also tested, defining case studies (S) to attend to the recurring managers’ decisions by minimizing: S1 – project cost, S2 – makespan, and S3 – workforce usage. The results reveal a robust model to support the forest planner in operational-level tasks. The ILP achieved the optimal solution only for the minimization of the project cost (S1) due to the delay in processing time of the other case studies. Thus, the SA stands out as an efficient method to solve the SSRCMM by providing satisfactory solutions in a reduced time. All the objective functions fitted properly with their proposed goals. The makespan and workforce usage functions increased by US$1,820.29 (S2) and US$2,146.39 (S3) from the S1, respectively, to finish the project earlier and reduce the oscillation of workforce usage over the days. Facing these findings, it is suggested that future researchers incorporate other challenges in decision-making, involving a multi-objective formulation or methods to reveal new insights for forest management and planning.

RESUMO Problemas de agendamento são tarefas da rotina operacional presentes nas empresas, que exigem uma solução ótima para apoiar a decisão. No entanto, esses problemas ainda não foram investigados com frequência na ciência florestal. Neste sentido, propôs-se descrever uma formulação matemática para a otimização da silvicultura sob restrição de agendamento da mão de obra/ sequenciamento das atividades (SSRRMM). Buscando o método mais adequado para solucionar este problema combinatório, comparou-se duas estratégias: i) Programação Linear Inteira (PLI) e ii) Simulated annealing (SA). Os principais critérios para avaliar o desempenho das estratégias foram fornecer soluções fáctiveis em tempo de processamento e custo final do projeto aceitáveis. A instância abordada é um problema real contendo 32 talhões e cinco atividades silviculturais programadas dentro de um prazo de 40 dias. Testou-se ainda três funções objetivo, definindo estudos de caso (S) para atender às decisões recorrentes dos gestores, minimizando: S1 - custo do projeto, S2 - makespan e S3 - utilização da mão de obra. Os resultados revelam um modelo robusto para apoiar o planejador florestal em tarefas a nível operacional. O PLI alcançou a solução ótima apenas para a minimização do custo do projeto (S1) devido à demora no tempo de processamento dos outros estudos de caso. Desta forma, destaca-se o SA como um método eficiente para solucionar o SSRRMM, fornecendo soluções satisfatórias em um tempo reduzido. Todas as funções objetivo se ajustaram adequadamente aos seus objetivos propostos. As funções de makespan e de uso da mão de obra aumentaram US$ 1.820,29 (S2) e US$ 2.146,39 (S3) em relação ao S1, respectivamente, para terminar o projeto mais cedo e reduzir a oscilação do uso da mão de obra ao longo dos dias. Diante dessas descobertas, sugere-se aos futuros pesquisadores incorporar outros desafios na tomada de decisão, envolvendo uma formulação multi-objetivo ou métodos para revelar novos insights dentro do manejo e planejamento florestal.

https://doi.org/10.1590/1806-908820220000002

Microbiological evaluation of industrialized and artisanal Minas fresh cheese commercialized in the Federal District, Brazil
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FERNANDES SILVA RODRIGUES, Letícia

; LUNARA SANTOS PAVELQUESI, Sabrina

; ALMEIDA DE OLIVEIRA FERREIRA, Ana Carolina

; DA SILVA MONTEIRO, Erika

; DE SOUZA SILVA, Calliandra Maria

; RODRIGUES DA SILVA, Izabel Cristina

; CASTILHO ORSI, Daniela

Food Science and Technology

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2022, Volume 42 elocation e45221

Abstract: En | Text: En | PDF: En

Abstract The aim of this study was to evaluate the microbiological quality of Minas fresh cheese commercialized in Federal District, Brazil. For this, 20 samples of industrialized cheeses were collected in supermarkets and 20 samples of artisanal cheeses were collected in public food markets. The analyzes performed were total count of bacteria, determination of coliforms, count of S. aureus and identification of Salmonella spp. (InvA gene) and S. aureus (SeC gene). The results showed that 26 samples (65%) were unfit for consumption according to Brazilian legislation. For industrialized cheeses, 6 samples (15%) of were unfit for consumption (3 samples for excess of thermotolerant coliforms and 3 samples for excess of S. aureus). For artisanal cheeses, all 20 samples (50%) were unfit for consumption due to the high S. aureus counts, including 6 samples that had excess thermotolerant coliforms and 1 sample that was contaminated with Salmonella. Comparing the results, industrialized cheeses showed better microbiological quality than artisanal cheeses. Thus, artisanal Minas fresh cheeses commercialized in the public food markets of the Federal District showed the presence of bacterial hazards, and there is an evident need for good hygiene practices in the entire production chain to ensure consumer food safety.

https://doi.org/10.1590/fst.45221

Síndrome congênita pelo vírus zika: análise das redes de apoio de pais
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Costa, Roama Paulo Ulisses Vaz da

; Lamy, Zeni Carvalho

; Oliveira, Poliana Soares de

; Carvalho, Ruth Helena de Souza Britto Ferreira de

; Pereira, Marina Uchoa Lopes

; Guimarães, Carolina Nívea Moreira

; Batista, Rosangela Fernandes Lucena

; Nascimento, Maria do Desterro Soares Brandão

Acta Paulista de Enfermagem

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2022, Volume 35 elocation eAPE02912

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo Comprender el papel de las redes de apoyo en el cuidado de niños afectados por el síndrome congénito por el virus del zika. Métodos Estudio cualitativo, realizado en un Centro de Referencia Regional en Neurodesarrollo, en el nordeste brasileño, entre abril de 2017 y febrero de 2018. Participaron padres de niños con microcefalia atendidos en el lugar. Se realizaron 18 entrevistas semiestructuradas, de las cuales tres fueron con el padre y la madre y 15 solo con madres, un total de 21 participantes. La muestra fue definida por el criterio de saturación y se utilizó análisis de contenido en la modalidad temática. Resultados Los resultados se presentan a partir de las categorías de análisis “red informal” y “red formal”. La red de apoyo informal, especialmente los abuelos, ejerció un importante soporte emocional y financiero para los padres. Las redes sociales virtuales se destacaron como un espacio para compartir información y experiencias. Respecto a la red de apoyo formal, las familias establecieron vínculos más fuertes con profesionales de la atención especializada, que ofrecieron soporte técnico y acogida a los padres y a los niños. Por otro lado, la atención primaria cumplió más el papel de derivar a la atención especializada. Se relataron diferentes niveles de resolución de problemas por parte de los municipios, en términos de programas, de actuación de gestores y de profesionales. Conclusión Las redes informales y formales actuaron de modo complementario en el tratamiento y apoyo a niños con síndrome congénito por el virus del zika. La inserción en diferentes redes informales permitió un apoyo social para enfrentar el impacto provocado por la enfermedad. A pesar de las inversiones en atención primaria del Ministerio de Salud, se identificó fragilidad en este nivel de atención.

Abstract Objective To understand the role of support networks in the care of children affected by Congenital Zika Syndrome. Methods This is a qualitative study, conducted at a State Reference Center on Neurodevelopment, in northeastern Brazil, between April 2017 and February 2018. Parents of children with microcephaly treated at the site participated. 18 semi-structured interviews were conducted, three with father and mother and 15 only with mothers, totaling 21 participants. The sample was defined by the saturation criterion and content analysis was used in the thematic modality. Results The results are presented from the categories of analysis “informal network” and “formal network”. The informal support network, especially grandparents, exercised important emotional and financial support to parents. Virtual social networks stood out as a space for sharing information and experiences. Regarding the formal support network, the families established stronger bonds with specialized care professionals who offered technical support and care to parents and children. Primary care, on the other, played the role of referral to specialized care. Different degrees of resolution were reported by the municipalities, in terms of programs, the performance of managers and professionals. Conclusion Formal and formal networks acted in a complementary way in the treatment and support of children with Congenital Zika Syndrome. The insertion in different indirect networks allowed social support to face the impact caused by the disease. Despite the ministry of health’s investment in primary care, fragility was identified in this level of care.

Resumo Objetivo Compreender o papel das redes de apoio no cuidado de crianças acometidas pela Síndrome Congênita pelo Vírus Zika. Métodos Estudo qualitativo, realizado em Centro de Referência Estadual em Neurodesenvolvimento, no nordeste brasileiro, entre abril de 2017 e fevereiro de 2018. Participaram pais de crianças com microcefalia atendidos no local. Foram realizadas 18 entrevistas semiestruturadas, sendo três com pai e mãe e 15 somente com mães, totalizando 21 participantes. A amostra foi definida pelo critério de saturação e foi utilizada análise de conteúdo na modalidade temática. Resultados Os resultados são apresentados a partir das categorias de análise “rede informal” e “rede formal”. A rede de apoio informal, especialmente os avós, exerceu importante suporte emocional e financeiro aos pais. As redes sociais virtuais se destacaram como espaço de compartilhamento de informações e experiências. Quanto à rede de apoio formal, as famílias estabeleceram vínculos mais fortes com profissionais da atenção especializada que ofertaram suporte técnico e acolhimento aos pais e às crianças. Já a atenção primária desempenhou mais o papel de encaminhamento para a atenção especializada. Foram relatados diferentes graus de resolutividade por parte dos municípios, em termos de programas, de atuação de gestores e de profissionais. Conclusão As redes informais e formais atuaram de modo complementar no tratamento e apoio às crianças com Síndrome Congênita pelo Vírus Zika. A inserção em diferentes redes informais possibilitou apoio social para enfrentar o impacto provocado pela doença. Apesar do investimento do Ministério da Saúde na atenção primária foi identificada fragilidade neste nível de atenção.

https://doi.org/10.37689/acta-ape/2022ao02912

Brazilian Guidelines for Nutrition in Cystic Fibrosis
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Neri, Lenycia de Cassya Lopes

; Simon, Miriam Isabel Souza dos Santos

; Ambrósio, Valéria Laguna Salomão

; Barbosa, Eliana

; Garcia, Monique Ferreira

; Mauri, Juliana Ferreira

; Guirau, Renata Rodrigues

; Neves, Mirella Aparecida

; Cunha, Carolina de Azevedo Pedrosa

; Nogueira, Marcelo Coelho

; Alves, Anna Carolina Di Creddo

; Gurmini, Jocemara

; Servidoni, Maria de Fatima

; Epifanio, Matias

; Athanazio, Rodrigo

einstein (São Paulo)

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2022, Volume 20 elocation eRW5686

Abstract: En | Text: En | PDF: En

ABSTRACT Objective To develop a scientific consensus on nutrition in cystic fibrosis. Methods Sixteen coordinators elaborated relevant questions on nutritional therapy in cystic fibrosis, which were divided into six sections: nutritional assessment, nutritional recommendations, nutritional intervention, dietary counseling, special situations and enzyme replacement, and gastrointestinal manifestations. Two to three specialists in the field were responsible for each section and obtaining answers formulated based on standardized bibliographic searches. The available literature was searched in the PubMed®/MEDLINE database, after training and standardization of search strategies, to write the best level of evidence for the questions elaborated. Issues related to disagreement were discussed until a consensus was reached among specialists, based on the current scientific literature. Results Forty-two questions were prepared and objectively answered, resulting in a consensus of nutritional therapy in cystic fibrosis. Conclusion This work enabled establishing a scientific consensus for nutritional treatment of cystic fibrosis patients.

https://doi.org/10.31744/einstein_journal/2022rw5686

Recommendations for evaluation and diagnosis of extra-glandular manifestations of primary Sjögren syndrome: results of an epidemiologic systematic review/ meta-analysis and a consensus guideline from the Brazilian society of rheumatology (hepatic, gastrointestinal and pancreatic)
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Trevisani, Virginia Fernandes Moça

; Pinheiro, Aysa César

; Fialho, Sonia Cristina de Magalhães Souza

; Fernandes, Marilena Leal Mesquita Silvestre

; Pugliesi, Alisson

; Pasoto, Sandra Gofinet

; Lopes, Maria Lucia Lemos

; Guedes, Lissiane Karine Noronha

; Miyamoto, Samira Tatiyama

; Santos, Laura Caldas dos

; Appenzeller, Simone

; Fidelix, Tania

; Ribeiro, Sandra Lúcia Euzébio

; Brito, Danielle Christinne Soares Egypto de

; Libório-Kimura, Tatiana Nayara

; Santos, Maria Carmen Lopes Ferreira Silva

; Cantali, Diego Ustárroz

; Gennari, Juliana D.’Agostino

; Capobianco, Karina Gatz

; Civile, Vinicius Tassoni

; Pinto, Ana Carolina Pereira Nunes

; Rocha, Aline Pereira da

; Rocha Filho, César Ramos

; Oliveira, Fabiola Reis

; Valim, Valeria

Advances in Rheumatology

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2022, Volume 62 elocation 35

Abstract: En | Text: En | PDF: En

Abstract Sjogren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration of the exocrine glands and other organs, associated with sicca syndrome but also with systemic involvement with varying degrees of severity. Despite their importance, some systemic manifestations, mainly liver, gastrointestinal, and pancreatic are not routinely evaluated. To address these manifestations, the Sjögren's Syndrome Committee of the Brazilian Society of Rheumatology conducted a broad systematic review of the literature on studies investigating prevalence and diagnosis of these symptoms in Sjogren´s patients and made recommendations based on the findings. Agreement between the experts was achieved using the Delphi method. This is the second part of this guideline, providing 6 recommendations for liver, gastrointestinal, and pancreatic care of SS patients.

https://doi.org/10.1186/s42358-022-00267-y

Recommendations for evaluation and diagnosis of extra-glandular manifestations of primary sjogren syndrome: results of an epidemiologic systematic review/ meta-analysis and a consensus guideline from the Brazilian Society of Rheumatology (articular, pulmonary and renal)
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Trevisani, Virginia Fernandes Moça

; Pugliesi, Alisson

; Pasoto, Sandra Gofinet

; Lopes, Maria Lucia Lemos

; Guedes, Lissiane Karine Noronha

; Miyamoto, Samira Tatiyama

; Fernandes, Marilena Leal Mesquita Silvestre

; Fialho, Sonia Cristina de Magalhães Souza

; Pinheiro, Aysa César

; Santos, Laura Caldas dos

; Appenzeller, Simone

; Fidelix, Tania

; Ribeiro, Sandra Lúcia Euzébio

; Brito, Danielle Christinne Soares Egypto de

; Libório-Kimura, Tatiana Nayara

; Santos, Maria Carmen Lopes Ferreira Silva

; Cantali, Diego Ustárroz

; Gennari, Juliana D’Agostino

; Civile, Vinicius Tassoni

; Pinto, Ana Carolina Pereira Nunes

; Rocha-Filho, César Ramos

; Oliveira, Fabiola Reis

; Rocha, Aline Pereira da

; Valim, Valeria

Advances in Rheumatology

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2022, Volume 62 elocation 18

Abstract: En | Text: En | PDF: En

Abstract Sjogren’s Syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration of the exocrine glands and other organs, associated with sicca syndrome but also with systemic involvement with varying degrees of severity. Despite their importance, these systemic manifestations are not routinely evaluated and there is no homogenous approach to their diagnosis or evaluation. To close this gap, a panel of experts from the Brazilian Society of Rheumatology conducted a systematic review and meta-analysis on the identification of epidemiologic and clinical features of these manifestations and made recommendations based on the findings. Agreement between the experts was achieved using the Delphi method. The first part of this guideline summarizes the most important topics, and 11 recommendations are provided for the articular, pulmonary, and renal care of SS patients.

https://doi.org/10.1186/s42358-022-00248-1

10.

Isolation and Characterization of Plant Growth-Promotion Diazotrophic Endophytic Bacteria Associated to Sugarcane (Saccharum officinarum L.) Grown in Paraíba, Brazil
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Antunes, Jadson Emanuel Lopes

; Freitas, Ana Dolores Santiago de

; Bonifacio, Aurenivia

; Oliveira, Louise Melo de Souza

; Santos, Carolina Etienne de Rosália e Silva

; Lyra, Maria do Carmo Catanho Pereira de

; Oliveira, José de Paula

; Ollero, Francisco Javier

; Araújo, Ademir Sérgio Ferreira de

; Figueiredo, Marcia do Vale Barreto

Brazilian Archives of Biology and Technology

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2022, Volume 65 elocation e22200439

Abstract: En | Text: En | PDF: En

Abstract: Sugarcane is an important Brazilian commodity, being usually cultivated in soils with low natural fertility. This study aimed to isolate diazotrophic endophytes from sugarcane tissues and evaluate the morphological and physiological characteristics of their colonies as well as their plant growth-promoting (PGP) traits in select diazotrophic endophytic bacteria. Fifty-six bacterial isolates were identified in the sugarcane tissues, and these isolates presented distinct morphological and physiological traits. A total of thirty-five bacterial isolates were biochemically evaluated. Overall, Bacillus was the dominant genus. Isolates of Methylobacterium spp. and Brevibacillus agri were present only in leaves, while Herbaspirillum seropedicae occurred only in stems. Except to IPA-CF45A, all isolates were nitrogenase positive. All endophytes exhibit production of indol 3-acetic acid. Over 50% of endophytes solubilize phosphate, release N-acyl homoserine lactones, and present the activity of 1-aminocyclopropane-1-carboxylic acid deaminase, catalase, lipase and protease. The network analysis showed that isolates belonged to Burkholderia, Herbaspirillum, and Methylobacterium interact with Bacillus. Bacterial endophytes exhibited distinct morphological, physiological, and PGP traits that are useful for sustainable agriculture, highlighting the isolates IPA-CC33, IPA-CF65, IPA-CC9 and IPA-CF27. Further studies on the effects of these diazotrophic endophytes and their potential for providing microbial inoculants for improving sugarcane fields will provide valuable information to maintain the sustainability and environment quality.

https://doi.org/10.1590/1678-4324-2022200439

11.

Technical performance of a lateral flow immunoassay for detection of anti-SARS-CoV-2 IgG in the outpatient follow-up of non-severe cases and at different times after vaccination: comparison with enzyme and chemiluminescent immunoassays
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Barreira, Gabriel Acca

; Santos, Emilly Henrique dos

; Pereira, Maria Fernanda Bádue

; Rodrigues, Karen Alessandra

; Rocha, Mussya Cisotto

; Kanunfre, Kelly Aparecida

; Marques, Heloisa Helena de Sousa

; Okay, Thelma Suely

; Eisencraft, Adriana Pasmanik

; Rossi Junior, Alfio

; Fante, Alice Lima

; Cora, Aline Pivetta

; Costa Reis, Amelia Gorete A. de

; Ferrer, Ana Paula Scoleze

; Andrade, Anarella Penha Meirelles de

; Watanabe, Andreia

; Gonçalves, Angelina Maria Freire

; Waetge, Aurora Rosaria Pagliara

; Silva, Camila Altenfelder

; Ceneviva, Carina

; Lazari, Carolina dos Santos

; Abellan, Deipara Monteiro

; Sabino, Ester Cerdeira

; Bianchini, Fabíola Roberta Marim

; Alcantara, Flávio Ferraz de Paes

; Ramos, Gabriel Frizzo

; Leal, Gabriela Nunes

; Rodriguez, Isadora Souza

; Pinho, João Renato Rebello

; Carneiro, Jorge David Avaizoglou

; Paz, Jose Albino

; Ferreira, Juliana Carvalho

; Ferranti, Juliana Ferreira

; Ferreira, Juliana de Oliveira Achili

; Framil, Juliana Valéria de Souza

; Silva, Katia Regina da

; Bastos, Karina Lucio de Medeiros

; Galleti, Karine Vusberg

; Cristofani, Lilian Maria

; Suzuki, Lisa

; Campos, Lucia Maria Arruda

; Perondi, Maria Beatriz de Moliterno

; Diniz, Maria de Fatima Rodrigues

; Fonseca, Maria Fernanda Mota

; Cordon, Mariana Nutti de Almeida

; Pissolato, Mariana

; Peres, Marina Silva

; Garanito, Marlene Pereira

; Imamura, Marta

; Dorna, Mayra de Barros

; Luglio, Michele

; Aikawa, Nadia Emi

; Degaspare, Natalia Viu

; Sakita, Neusa Keico

; Udsen, Nicole Lee

; Scudeller, Paula Gobi

; Gaiolla, Paula Vieira de Vincenzi

; Severini, Rafael da Silva Giannasi

; Rodrigues, Regina Maria

; Toma, Ricardo Katsuya

; Paula, Ricardo Iunis Citrangulo de

; Palmeira, Patricia

; Forsait, Silvana

; Farhat, Sylvia Costa Lima

; Sakano, Tânia Miyuki Shimoda

; Koch, Vera Hermina Kalika

; Cobello Junior, Vilson

Revista do Instituto de Medicina Tropical de São Paulo

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2022, Volume 64 elocation e49

Abstract: En | Text: En | PDF: En

ABSTRACT This study assessed the technical performance of a rapid lateral flow immunochromatographic assay (LFIA) for the detection of anti-SARS-CoV-2 IgG and compared LFIA results with chemiluminescent immunoassay (CLIA) results and an in-house enzyme immunoassay (EIA). To this end, a total of 216 whole blood or serum samples from three groups were analyzed: the first group was composed of 68 true negative cases corresponding to blood bank donors, healthy young volunteers, and eight pediatric patients diagnosed with other coronavirus infections. The serum samples from these participants were obtained and stored in a pre-COVID-19 period, thus they were not expected to have COVID-19. In the second group of true positive cases, we chose to replace natural cases of COVID-19 by 96 participants who were expected to have produced anti-SARS-CoV-2 IgG antibodies 30-60 days after the vaccine booster dose. The serum samples were collected on the same day that LFIA were tested either by EIA or CLIA. The third study group was composed of 52 participants (12 adults and 40 children) who did or did not have anti-SARS-CoV-2 IgG antibodies due to specific clinical scenarios. The 12 adults had been vaccinated more than seven months before LFIA testing, and the 40 children had non-severe COVID-19 diagnosed using RT-PCR during the acute phase of infection. They were referred for outpatient follow-up and during this period the serum samples were collected and tested by CLIA and LFIA. All tests were performed by the same healthcare operator and there was no variation of LFIA results when tests were performed on finger prick whole blood or serum samples, so that results were grouped for analysis. LFIA’s sensitivity in detecting anti-SARS-CoV-2 IgG antibodies was 90%, specificity 97.6%, efficiency 93%, PPV 98.3%, NPV 86.6%, and likelihood ratio for a positive or a negative result were 37.5 and 0.01 respectively. There was a good agreement (Kappa index of 0.677) between LFIA results and serological (EIA or CLIA) results. In conclusion, LFIA analyzed in this study showed a good technical performance and agreement with reference serological assays (EIA or CLIA), therefore it can be recommended for use in the outpatient follow-up of non-severe cases of COVID-19 and to assess anti-SARS-CoV-2 IgG antibody production induced by vaccination and the antibodies decrease over time. However, LFIAs should be confirmed by using reference serological assays whenever possible.

https://doi.org/10.1590/s1678-9946202264049

12.

Physiotherapy practice for hospitalized patients with COVID-19
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Dias, Letícia Marcelino Sotelo

; Guimaraes, Fernando Silva

; Leite, Camila Ferreira

; Paro, Flavia Marini

; Annoni, Raquel

; Oliveira, Ana Carolina Otoni

; Accioly, Marilita Falangola

; Volpe, Marcia Souza

Jornal Brasileiro de Pneumologia

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2022, Volume 48 N. 4 elocation e20220121

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Objective: To identify the indications for physiotherapy and to evaluate physiotherapy practices in patients with COVID-19 admitted to the ICU (on mechanical ventilation) or to the ward (spontaneously breathing). Methods: An online, 50-item survey was completed by physiotherapists who had been treating hospitalized patients with COVID-19 in Brazil. Results: Of the 644 physiotherapists who initiated the survey, 488 (76%) completed it. The main reasons for indications for physiotherapy in both settings reported as “very frequently” and “frequently” both in the ICU and the ward by most respondents were oxygenation improvement (> 95%) and prevention of general complications (> 83%). Physical deconditioning was considered an infrequent indication. When compared with mobilization strategies, the use of respiratory interventions showed great variability in both work settings, and techniques considered effective were underutilized. The most frequently used respiratory techniques in the ICU were positioning (86%), alveolar recruitment (73%), and hard/brief expiratory rib cage compression (46%), whereas those in the ward were active prone positioning (90%), breathing exercises (88%), and directed/assisted cough (75%). The mobilization interventions reported by more than 75% of the respondents were sitting on the edge of the bed, active and resistive range of motion exercises, standing, ambulation, and stepping in place. Conclusions: The least common reason for indications for physiotherapy was avoidance of deconditioning, whereas oxygenation improvement was the most frequent one. Great variability in respiratory interventions was observed when compared with mobilization therapies, and there is a clear need to standardize respiratory physiotherapy treatment for hospitalized patients with COVID-19.

RESUMO Objetivo: Identificar as indicações de fisioterapia e avaliar as práticas fisioterapêuticas em pacientes com COVID-19 internados na UTI (em ventilação mecânica) ou na enfermaria (em respiração espontânea). Métodos: Questionário online, com 50 questões, respondido por fisioterapeutas que atendiam pacientes hospitalizados com COVID-19 no Brasil. Resultados: Dos 644 fisioterapeutas que iniciaram o questionário, 488 (76%) o concluíram. As principais indicações de fisioterapia relatadas como “muito frequente” e “frequentemente” tanto na UTI quanto na enfermaria pela maioria dos respondentes foram melhora da oxigenação (> 95%) e prevenção de complicações gerais (> 83%). Descondicionamento físico foi considerado uma indicação pouco frequente. Em comparação com as estratégias de mobilização, as intervenções respiratórias apresentaram grande variabilidade em ambos os setores de trabalho, e técnicas consideradas eficazes foram subutilizadas. As técnicas respiratórias mais utilizadas na UTI foram posicionamento (86%), recrutamento alveolar (73%) e compressão torácica expiratória forte e rápida (46%), enquanto, na enfermaria, as mais utilizadas foram posição prona ativa (90%), exercícios respiratórios (88%) e tosse assistida/dirigida (75%). As intervenções de mobilização relatadas por mais de 75% dos respondentes foram sedestação a beira leito, exercícios ativos e resistidos de membros superiores/inferiores, ortostatismo, deambulação e marcha estacionária. Conclusões: A indicação menos frequente de fisioterapia foi prevenção do descondicionamento, enquanto melhora da oxigenação foi a mais frequente. Observou-se grande variabilidade nas intervenções respiratórias em comparação com as terapias de mobilização, e há uma clara necessidade de padronização do tratamento fisioterapêutico respiratório para pacientes hospitalizados com COVID-19.

https://doi.org/10.36416/1806-3756/e20220121

13.

Profile of pharmaceutical interventions of a pharmacotherapeutic follow-up model for diabetic patients in a community pharmacy
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Silva, William Lucas Ferreira da

; Matos, Dalyara Mendonça de

; Felicíssimo, Juliane Marques

; Jardim, Ana Carolina Bellose

; Cruz, Danielle Teles da

; Cazarim, Maurílio de Souza

; Mendonça, Alessandra Esthér de

; Silvério, Marcelo Silva

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e20956

Abstract: En | Text: En | PDF: En

Abstract The insertion of Pharmaceutical Care in Primary Health Care (PHC) improves patients’ clinical outcomes and quality of life. Pharmacotherapeutic follow-up can contribute to the management of chronic diseases such as diabetes, promoting better glycemic control and adherence to therapy. This study aimed to assess the Drug-therapy Problems (DTPs) and Pharmacist Interventions (PIs) on the pharmacotherapeutic management in patients with type 2 diabetes mellitus (T2DM) in a community pharmacy. A quantitative, retrospective, and cross-sectional study was conducted in a Pharmaceutical Care Program within the PHC in Juiz de Fora (Minas Gerais, Brazil). Inclusion criteria were patients with T2DM above 18, who attended at least three pharmaceutical consultations between July 2016 and October 2018 and presented two or more glycated hemoglobin tests. The study group (n = 17) was largely composed of women (65%), elderly (76%), sedentary (72%), and obese people (52%). The resolution was achieved in 79% of the DTPs identified (n = 115). Most of DTPs were related to administration and adherence to pharmacotherapy (46%). 60% of the 437 PIs involved the provision of information and counseling. In other words, accessible interventions lead to high resolvability. Therefore, clinical actuation of pharmacists could improve the prognosis in diabetes treatment.

https://doi.org/10.1590/s2175-97902022e20956

14.

SILVICULTURAL TASKS SCHEDULING OPTIMIZATION: A CASE STUDY OF FUNCTIONS AND METHODS
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Mendonça, Nathalia de Paiva

; Lopes, Isáira Leite e

; Gomes, Vanessa de Souza

; Ferreira, Matheus Andrade

; Cruz, Bruno Rogério

; Silva, Carolina Souza Jarochinski e

; Gomide, Lucas Rezende

Revista Árvore

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2022, Volume 46 elocation e4602

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1806-908820220000002

15.

Direitos da criança e adolescente hospitalizados à luz da gestão da clínica
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Peixoto, Carolina Souza

; Moraes, Leidiely Gomes

; Marques, Mariene Araújo Rodrigues

; Alves, Mayrene Dias de Sousa Moreira

; Gaíva, Maria Aparecida Munhoz

; Ferreira, Gímerson Erick

; Ribeiro, Mara Regina Rosa

Acta Paulista de Enfermagem

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2022, Volume 35 elocation eAPE0278345

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Objetivo Analizar el (in)cumplimiento de los Derechos del Niño y del Adolescente hospitalizados a la luz de la gestión de la clínica. Métodos Investigación con métodos mixtos, explanatoria secuencial, realizada entre septiembre y diciembre de 2019, en un hospital universitario del medio oeste de Brasil. Participaron 60 acompañantes, ocho profesionales y cuatro estudiantes del área de la salud, en sectores de internación de niños y de adolescentes. Se aplicó una escala Likert con los veinte derechos en la etapa cuantitativa, y entrevista semiestructurada en la cualitativa, con análisis descriptivo y de contenido, respectivamente. Los datos se integraron por conexión y fueron analizados a la luz de principios de la gestión de la clínica. Resultados En la etapa cuantitativa, se identificaron derechos con menores porcentajes de cumplimiento: permanecer al lado de la madre al nascer, lactancia materna, apoyo psicológico, recreación, acompañamiento del currículum escolar y muerte digna. En los resultados cualitativos se identificó un desconocimiento de la resolución de parte de los participantes, considerando parcialmente cumplidos los derechos: no permanecer internado sin necesidad, tener un acompañante, no separarse de la madre en el nacimiento, lactancia materna, no sentir dolor, conocimiento de la enfermedad, disfrutar de la recreación y programas educativos, recibir información, todos los recorridos para la curación, protección contra malos tratos, preservación de la imagen, no ser utilizado por los medios y tener una muerte digna. Se identificaron principios de la gestión de la clínica limitados, exigiendo estrategias de fomento en el hospital. Conclusión Principios de la gestión de la clínica se mostraron fragilizados, especialmente los de orientación a las necesidades de salud e integralidad, transparencia y responsabilización social.

Abstract Objective To analyze the (non)compliance with the rights of hospitalized children and adolescents in light of clinic management. Methods This is a mixed methods research, sequential explanatory, carried out between September and December 2019, in a university hospital in center-western Brazil. Sixty companions, eight professionals and four health care students participated in hospitalization sectors for children and adolescents. A Likert-type scale was applied with the twenty rights in the quantitative stage, and semi-structured interviews in the qualitative stage, with descriptive and content analysis, respectively. Data were integrated by connection and analyzed in light of clinic management principles. Results In the quantitative stage, rights were identified with the lowest percentages of compliance: staying by the mother’s side at birth, being breastfed, psychological support, recreation, monitoring the school curriculum and dignified death. In the qualitative results, it was identified that participants did not know about the resolution, considering that the rights were partially complied with: not being hospitalized unnecessarily, having a companion, not being separated from the mother at birth, being breastfed, not feeling pain, knowing the disease, enjoying recreation and educational programs, receiving information, all resources for healing, protection against abuse, preservation of image, not being used by the media and having a dignified death. Limited principles of clinic management were identified, requiring development strategies in the hospital. Conclusion Principles of clinic management were weakened, especially those related to health needs and comprehensiveness, transparency and social accountability.

Resumo Objetivo Analisar o (des)cumprimento dos Direitos da Criança e Adolescente hospitalizados à luz da gestão da clínica. Métodos Pesquisa de métodos mistos, explanatória sequencial, realizada entre setembro e dezembro de 2019, em hospital universitário do Centro-Oeste do Brasil. Participaram 60 acompanhantes, oito profissionais e quatro estudantes da área da saúde, em setores de internação de crianças e adolescentes. Aplicou-se escala Likert com os vinte direitos na etapa quantitativa, e entrevista semiestruturada na qualitativa, com análise descritiva e de conteúdo, respectivamente. Os dados foram integrados por conexão e analisados à luz de princípios da gestão da clínica. Resultados Na etapa quantitativa, identificaram-se direitos com menores percentuais de cumprimento: permanecer ao lado da mãe ao nascer, receber aleitamento materno, apoio psicológico, recreação, acompanhamento do currículo escolar e morte digna. Nos resultados qualitativos identificou-se desconhecimento da resolução pelos participantes, considerando parcialmente cumpridos os direitos: não permanecer internado desnecessariamente, ter acompanhante, não ser separado da mãe ao nascer, receber aleitamento materno, não sentir dor, conhecimento da enfermidade, desfrutar de recreação e programas educacionais, receber informação, todos os recursos para cura, proteção contra maus tratos, preservação de imagem, não ser utilizado pela mídia e ter morte digna. Identificaram-se princípios da gestão da clínica limitados, exigindo estratégias de fomento no hospital. Conclusão Princípios da gestão da clínica mostraram-se fragilizados, especialmente os de orientação às necessidades de saúde e integralidade, transparência e responsabilização social..

https://doi.org/10.37689/acta-ape/2022ao0278345

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