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Abstract: Processing consists of sequential operations aimed at cleaning, classifying, and treating seeds, with the goal of improving the quality of the lot. The aim of this study was to evaluate the effect of the processing stages on the physical and physiological quality of chickpea seeds, cultivar BRS Cícero. Seeds were sampled before processing and after passing through the air screen machine (upper sieve of 12 mm and lower sieve of 7.5 mm), elevators, storage silo, and gravity table (upper discharge, high intermediate, low intermediate, and lower discharge). The seeds were evaluated for moisture content, physical purity, germination test, electrical conductivity test, emergence in sand, emergence speed index, accelerated aging, and tetrazolium test. The processing resulted in increased physical purity and reduced percentage of broken seeds in the lot of chickpea seeds. Seeds collected from the upper and intermediate chutes of the gravity table showed higher germination values. Seed processing using the air screen machine and the gravity table is effective in improving the physical and physiological quality of the lot of chickpea seeds, cultivar BRS Cícero.

Resumo: O beneficiamento consiste em operações sequenciais que visam limpar, classificar e tratar as sementes, visando a melhoria da qualidade do lote. Objetivou-se com este trabalho avaliar o efeito das etapas de beneficiamento na qualidade física e fisiológica de sementes de grão-de-bico, cultivar BRS Cícero. As sementes foram amostradas antes do processamento e após a saída da máquina de ventilador e peneiras (peneira superior de 12 mm e inferior de 7,5 mm), elevadores, silo armazenador e mesa de gravidade (descarga superior, intermediária alta, intermediária baixa e inferior). As sementes foram avaliadas quanto aos teores de água, pureza física, teste de germinação, teste de condutividade elétrica, emergência em areia, índice de velocidade de emergência, envelhecimento acelerado e teste de tetrazólio. O beneficiamento promoveu o aumento da pureza física e redução do percentual de sementes quebradas no lote de sementes de grão-de-bico. As sementes coletadas nas bicas superiores e intermediárias da mesa de gravidade apresentaram valores superiores de germinação. O beneficiamento de sementes, utilizando a máquina de ar e peneiras e a mesa de gravidade, é eficiente para o aprimoramento da qualidade física e fisiológica do lote de sementes de grão-de-bico cultivar BRS Cícero.

https://doi.org/10.1590/2317-1545v45268779

Effect of immunonutrition on serum levels of C-reactive protein and lymphocytes in patients with COVID-19: a randomized, controlled, double-blind clinical trial
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Pimentel, Rodrigo Fernandes Weyll

; Silva, Arthur Pinto

; Santana, Amália Ivine Costa

; Souza e Silva, Douglas de

; Ramos, Mariângela de Souza

; de Souza, Márcio Costa

; Suen, Vivian Marques Miguel

; Maduro, Isolda Padro de Negreiros Nogueira

; Filho, Durval Ribas

; Júnior, Argemiro D'Oliveira

; da Silva, Dandara Almeida Reis

; Coelho, Julita Maria Freitas

; Gomes, Antonio Marcos Tosoli

; Machado, Paulo Roberto Lima

; das Merces, Magno Conceição

Nutrición Hospitalaria

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feb 2022, Volume 39 N. 1 Pages 20 - 26

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Introduction: patients with COVID-19 undergo changes in leukocyte count, respiratory disorders, and an increase in inflammatory substances. To improve the inflammatory condition, some nutrients can be used, including arginine, omega-3 fatty acids and nucleotides. This study aims to evaluate how oral immunonutrient supplements affects serum C-reactive protein (CRP) levels and lymphocyte count in patients with COVID-19. Methods: in this double-blind clinical trial, we randomized 43 adult patients with COVID-19 to receive a standard high-protein normocaloric supplement (control) or an immunonutrient-enriched supplement (experiment) for 7 days. The primary outcome was to evaluate changes in total lymphocyte count and serum level of CRP. The assessment of risk and nutritional status of these patients was also performed. Results: forty-three patients with mean age of 41.5 (± 1.8) years were followed up, 39.5 % of them women. The mean body mass index was 27.6 (± 0.8) kg/m² and 58.1 % had low nutritional risk. In the experiment group, there was a CRP reduction of 23.6 (± 7.5) mg/L, while in the control branch the decrease was 14.8 (± 12.1) mg/L (p = 0.002). There was an increase in lymphocytes in the experiment group (+367.5 ± 401.8 cells/mm³) and a reduction in the control group (-282.8 ± 327.8 cells/mm³), although there was no statistical significance (p = 0.369). Relative risk (RR) of treatment in reducing CRP by 30 % or more was 4.45 (p < 0.001; 95 % CI, 1.79-11.07). RR in increasing lymphocyte count by 30 % or more was 1.28 (p = 0.327; 95 % CI, 0.67-2.45). Conclusion: we conclude that immunonutrient supplements seem to reduce CRP levels more than standard high-protein normocaloric supplements.

Resumen Introducción: los pacientes con COVID-19 sufren cambios en el recuento de leucocitos, trastornos respiratorios y aumento de sustancias inflamatorias. Para mejorar la condición inflamatoria se pueden usar algunos nutrientes, como la arginina, los ácidos grasos omega-3 y los nucleótidos. Este estudio tiene como objetivo evaluar cómo los suplementos de inmunonutrientes orales afectan a los niveles séricos de proteína C-reactiva (PCR) y al recuento de linfocitos en pacientes con COVID-19. Métodos: en este ensayo clínico doble ciego, aleatorizamos a 43 pacientes adultos con COVID-19 para recibir un suplemento normocalórico estándar alto en proteínas (control) o un suplemento enriquecido con inmunonutrientes (experimento) durante 7 días. El resultado primario fue evaluar los cambios en el recuento total de linfocitos y el nivel sérico de PCR. También se realizó la evaluación del riesgo y el estado nutricional de estos pacientes. Resultados: cuarenta y tres pacientes con edad media de 41,5 (± 1,8) años fueron seguidos, el 39,5 % de ellos mujeres. El índice de masa corporal medio fue de 27,6 (± 0,8) kg/m² y el 58,1 % tenían bajo riesgo nutricional. En el grupo experimental hubo una reducción de la PCR de 23,6 (± 7,5) mg/L, mientras que en la rama de control la disminución fue de 14,8 (± 12,1) mg/L (p = 0,002). Hubo un aumento de linfocitos en el grupo experimental (+367,5 ± 401,8 células/mm³) y una reducción en el grupo de control (-282,8 ± 327,8 células/mm³), aunque no hubo significación estadística (p = 0,369). El riesgo relativo (RR) del tratamiento para reducir la PCR en un 30 % o más fue de 4,45 (p < 0,001; IC 95 %: 1,79-11,07). El RR en el aumento del recuento de linfocitos en un 30 % o más fue de 1,28 (p = 0,327; IC 95 %: 0,67-2,45). Conclusión: se concluye que los suplementos de inmunonutrientes parecen reducir los niveles de PCR más que los suplementos normocalóricos estándar altos en proteína.

https://doi.org/10.20960/nh.03847

Periodontal status of maxillary central incisors after orthodontic traction: a longitudinal follow-up
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Calil, Louise Resti

; Janson, Guilherme

; Silva, Vinicius Merino da

; Freitas, Marcos Roberto de

; Almeida, Ana Lúcia Pompéia Fraga de

; Garib, Daniela

Journal of Applied Oral Science

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2022, Volume 30 elocation e20210492

Abstract: En | Text: En | PDF: En

Abstract The aim of this study was to evaluate the clinical and radiographic periodontal status of impacted permanent maxillary central incisors (Mx.1) after a long term of orthodontic traction. Methodology This split-mouth study evaluated a sample of 11 patients (five females, six males) treated with Mx.1 unilateral traction one to 28 years after the removal of orthodontic appliances. The traction Group (TG) consisted of 11 Mx.1 and the Comparison Group (CG) comprised 11 spontaneously erupted contralateral Mx.1. High-resolution CBCT exams of central incisors were performed using Accuitomo (J. Morita, Kyoto, Japan). Cross-section imagens passing through the center of maxillary central incisors were used to measure buccal and lingual alveolar bone level. Presence of fenestration, root dilacerations, root coverage, and position of the root apex were also assessed in the same images. Clinical parameters included periodontal probing depth, attachment level, gingival bleeding index, plaque index, degree of gingival recession, amount of gingival mucosa, and evaluation of interproximal papilla and black triangle. Digital model analysis included an assessment of clinical crown height and width. Intergroup comparisons were performed using paired t-, McNemar’s, and Wilcoxon tests (p<0.05). Results Compared to CG, we found a significantly thinner labial bone plate thickness in TG at the middle (p=0.000) and apical (p=0.009) root level. We also observed an apical displaced labial bone crest level in TG (p=0.000). The Traction Group showed a greater frequency of root dilacerations and gingival recessions, a decreased amount of keratinized mucosa, and a decreased clinical attachment level at the labial aspect compared to contralateral teeth. Conclusions A decreased thickness and height of labial alveolar bone and gingival recessions were found in maxillary central incisors 15 years after orthodontic traction. Though incisor traction might cause some periodontal impact, differences are acceptable under a clinical point of view considering the cost-benefit ratio.

https://doi.org/10.1590/1678-7757-2021-0492

Triatomine fauna in the state of Bahia, Brazil: What changed after 40 years of the vector-control program?
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Ribeiro-Jr, Gilmar

; Araújo, Renato Freitas de

; Carvalho, Cristiane Medeiros Moraes de

; Cunha, Gabriel Muricy

; Lanza, Fernanda Cardoso

; Miranda, Diego Lopes Paim

; Sousa, Orlando Marcos Farias de

; Santos, Carlos Gustavo Silva dos

; Fonseca, Eduardo Oyama Lins

; Santos, Roberto Fonseca dos

; Reis, Renato Barbosa

; Gurgel-Gonçalves, Rodrigo

; Reis, Mitermayer Galvão

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 elocation e0732-2021

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Neglected tropical diseases are a growing threat to global health, and endemic Chagas disease has emerged as one of the most important health problems in America. The main strategy to prevent Trypanosoma cruzi transmission is chemical control of vectors. This study presents a descriptive analysis of synanthropic triatomines before and after the implementation of a vector-control program in Bahia, Brazil. Methods: Descriptive analysis and geospatial statistics were performed on triatomine data, (1) the relative abundance and (2) proportional spatial distribution, from Bahia during two periods: (A) 1957 to 1971 and (B) 2006 to 2019. Results: We observed a decrease in the relative abundance of Panstrongylus megistus (A: n=22.032, 61.9%; B: n=1.842, 1.0%) and Triatoma infestans (A: n=1.310, 3.7%; B: n=763, 0.43%), as well as an increase in the relative abundance of T. sordida (A: n=8.314, 23.4%, B: n=146.901, 81.6%) and T. pseudomaculata (A: n=894, 2.5%, B: n=16.717, 9.3%). Conclusions: Our results indicate a clear reduction in the occurrence of P. megistus and T. infestans (last record in 2015) and an increase in the relative abundance and geographical distribution of T. sordida and T. pseudomaculata after 40 years of the vector-control program. The high frequency of other triatomine species in the municipalities of the state of Bahia and their abundance in recent years highlight the need to reinforce permanent entomological surveillance actions to prevent Chagas disease.

https://doi.org/10.1590/0037-8682-0732-2021

Diretriz de Miocardites da Sociedade Brasileira de Cardiologia – 2022
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Montera, Marcelo Westerlund

; Marcondes-Braga, Fabiana G.

; Simões, Marcus Vinícius

; Moura, Lídia Ana Zytynski

; Fernandes, Fabio

; Mangine, Sandrigo

; Oliveira Júnior, Amarino Carvalho de

; Souza, Aurea Lucia Alves de Azevedo Grippa de

; Ianni, Bárbara Maria

; Rochitte, Carlos Eduardo

; Mesquita, Claudio Tinoco

; de Azevedo Filho, Clerio F.

; Freitas, Dhayn Cassi de Almeida

; Melo, Dirceu Thiago Pessoa de

; Bocchi, Edimar Alcides

; Horowitz, Estela Suzana Kleiman

; Mesquita, Evandro Tinoco

; Oliveira, Guilherme H.

; Villacorta, Humberto

; Rossi Neto, João Manoel

; Barbosa, João Marcos Bemfica

; Figueiredo Neto, José Albuquerque de

; Luiz, Louise Freire

; Hajjar, Ludhmila Abrahão

; Beck-da-Silva, Luis

; Campos, Luiz Antonio de Almeida

; Danzmann, Luiz Cláudio

; Bittencourt, Marcelo Imbroinise

; Garcia, Marcelo Iorio

; Avila, Monica Samuel

; Clausell, Nadine Oliveira

; Oliveira Jr, Nilson Araujo de

; Silvestre, Odilson Marcos

; Souza, Olga Ferreira de

; Mourilhe-Rocha, Ricardo

; Kalil Filho, Roberto

; Al-Kindi, Sadeer G.

; Rassi, Salvador

; Alves, Silvia Marinho Martins

; Ferreira, Silvia Moreira Ayub

; Rizk, Stéphanie Itala

; Mattos, Tiago Azevedo Costa

; Barzilai, Vitor

; Martins, Wolney de Andrade

; Schultheiss, Heinz-Peter

Arquivos Brasileiros de Cardiologia

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2022, Volume 119 N. 1 Pages 143 - 211

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220412

Desenvolvimento de compósitos poliméricos reforçados com fibra da folha do buriti
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Pereira, Warley Augusto

; Ceron, Igor

; Silva, Matheus Souza e

; Freitas, Marcos Paulo Chaves de

; Silva, Edson Roberto da

; Costa, Fabíola Medeiros da

Matéria (Rio de Janeiro)

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2021, Volume 26 N. 1 elocation e12932

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo desta pesquisa foi estudar a viabilidade, com relação à resistência à tração, da utilização da folha de buriti como reforço em compósitos com fibras contínuas unidirecionais em matriz polimérica. Como matriz, foram utilizadas as resinas de poliéster isoftálico, de poliéster ortoftálico e de epóxi. Analisou-se a resistência à tração da fibra, das resinas e dos compósitos confeccionados com cada polímero. Testes de arrancamento foram realizados para verificar a adesão da fibra nas resinas usadas como matriz. Foi feita uma caracterização da fibra através de microscopia óptica e com microscópio eletrônico de varredura (MEV), além da determinação de sua densidade. Quanto à estrutura, observou-se que as fibras possuem uma lacuna central entre as faces adaxial e abaxial e que há um enrolamento da fibra. Os ensaios de arrancamento mostraram que houve maior adesão entre a fibra da folha de buriti e a matriz de epóxi, com um comprimento crítico lc = 1,0 mm, seguido pela matriz de poliéster isoftálico, com lc = 2,8 mm, e pela matriz de poliéster ortoftálico, com lc = 26,8 mm. A fibra apresentou resistência à tração variando entre 100,8 MPa e 224,1 MPa. Verificou-se que a resistência à tração das fibras é maior para diâmetros menores. Entre as resinas estudadas, a de epóxi foi a que apresentou maior resistência média à tração (60,5 MPa), seguido pela de poliéster isoftálico (34,5 MPa) e pela de poliéster ortoftálico (27,7 MPa). Testes com os compósitos criados mostraram que a matriz de epóxi é a mais promissora quanto à resistência à tração, seguida pela matriz de poliéster isoftálico. A matriz de poliéster ortoftálico apresentou valores de resistência bem abaixo da demais. Conclui-se que a fibra da folha de buriti apresentou um bom potencial para a produção de compósitos leves e resistentes.

ABSTRACT The objective of this research was to study the viability, with respect to tensile strength, of using buriti leaf as reinforcement in composites with unidirectional continuous fibers in polymeric matrix. As matrix, isophthalic polyester, orthophthalic polyester and epoxy resins were used. The tensile strength of fiber, resins and composites confectioned with each polymer was analyzed. Pullout tests were performed to verify fiber adhesion with the resins used as matrix. The fiber was characterized by optical microscopy and using a scanning electron microscope (SEM) in addition to determining its density. Regarding the structure, it was observed that the fibers have a central gap between the adaxial and abaxial faces and that there is a winding of the fiber. The pullout tests showed that there was greater adhesion between the buriti leaf fiber and the epoxy matrix, with a critical length lc = 1.0 mm, followed by the isophthalic polyester matrix, with lc = 2.8 mm, and the matrix of orthophthalic polyester with lc = 26.8 mm. The fiber presented tensile strength ranging from 100.8 MPa to 224.1 MPa. It was found that the tensile strength of the fibers is higher for smaller diameters. Among the resins studied, epoxy showed the highest average tensile strength (60.5 MPa), followed by isophthalic polyester (34.5 MPa) and orthophthalic polyester (27.7 MPa). Tests with the composites created showed that the epoxy matrix is the most promising as tensile strength, followed by the isophthalic polyester matrix. The orthophthalic polyester matrix presented resistance values much below the others. It was concluded that the buriti leaf fiber presented a good potential for the production of light and resistant composites.

https://doi.org/10.1590/s1517-707620210001.1232 587 downloads

Implementation of Tele-ICU during the COVID-19 pandemic
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Macedo, Bruno Rocha de

; Garcia, Marcos Vinicius Fernandes

; Garcia, Michelle Louvaes

; Volpe, Marcia

; Sousa, Mayson Laércio de Araújo

; Amaral, Talita Freitas

; Gutierrez, Marco Antônio

; Barbosa, Antonio Pires

; Scudeller, Paula Gobi

; Caruso, Pedro

; Carvalho, Carlos Roberto Ribeiro

Jornal Brasileiro de Pneumologia

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2021, Volume 47 N. 2 elocation e20200545

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever a implantação de um serviço de telemedicina de UTI durante a pandemia de COVID-19, assim como descrever e analisar os resultados dos primeiros quatro meses de funcionamento do programa. Métodos: Estudo observacional descritivo da implantação de um serviço de telemedicina de UTI seguido de análise retrospectiva dos dados clínicos de pacientes com COVID-19 internados em UTI entre abril e julho de 2020. Resultados: O serviço foi implantado em quatro semanas e mostrou-se viável em meio à pandemia. O treinamento foi desenhado para ser remoto e baseado em evidências, promovendo a padronização do atendimento aos pacientes com COVID-19. Mais de 100.000 visualizações foram registradas nas plataformas on-line de acesso livre e no aplicativo móvel. Durante o período do estudo, os casos de 326 pacientes com COVID-19 foram avaliados no programa. A mediana de idade foi de 60 anos (variação: 49-68 anos). Houve predomínio do sexo masculino (56%) e alta prevalência de hipertensão arterial (49,1%) e diabetes mellitus (38,4%). Na admissão na UTI, 83,7% dos pacientes estavam em ventilação mecânica invasiva, com uma mediana da relação PaO2/FiO2 < 150. Ventilação pulmonar protetora foi possível em 75% dos casos. A mortalidade na UTI foi de 65%, e a mortalidade hospitalar foi de 68%. Conclusões: A telemedicina de UTI forneceu treinamento multidisciplinar aos profissionais de saúde e acompanhamento clínico de centenas de pacientes críticos. A iniciativa na rede pública foi pioneira e mostrou-se viável em meio à pandemia de COVID-19, incentivando a criação de projetos semelhantes que combinem práticas baseadas em evidências, treinamento e telemedicina.

ABSTRACT Objective: To describe the implementation of a Tele-ICU program during the COVID-19 pandemic, as well as to describe and analyze the results of the first four months of operation of the program. Methods: This was a descriptive observational study of the implementation of a Tele-ICU program, followed by a retrospective analysis of clinical data of patients with COVID-19 admitted to ICUs between April and July of 2020. Results: The Tele-ICU program was implemented over a four-week period and proved to be feasible during the pandemic. Participants were trained remotely, and the program had an evidence-based design, the objective being to standardize care for patients with COVID-19. More than 100,000 views were recorded on the free online platforms and the mobile application. During the study period, the cases of 326 patients with COVID-19 were evaluated through the program. The median age was 60 years (IQR, 49-68 years). There was a predominance of males (56%). There was also a high prevalence of hypertension (49.1%) and diabetes mellitus (38.4%). At ICU admission, 83.7% of patients were on invasive mechanical ventilation, with a median PaO2/FiO2 ratio < 150. It was possible to use lung-protective ventilation in 75% of the patients. Overall, in-hospital mortality was 68%, and ICU mortality was 65%. Conclusions: Our Tele-ICU program provided multidisciplinary training to health care professionals and clinical follow-up for hundreds of critically ill patients. This public health care network initiative was unprecedented and proved to be feasible during the COVID-19 pandemic, encouraging the creation of similar projects that combine evidence-based practices, training, and Tele-ICU.

https://doi.org/10.36416/1806-3756/e20200545 745 downloads

Factors affecting the stability of maxillary extraction site closure
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BRESSANE, Larissa

; JANSON, Guilherme

; NAVEDA, Rodrigo

; FREITAS, Marcos Roberto de

; GARIB, Daniela

Dental Press Journal of Orthodontics

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2021, Volume 26 N. 2 elocation e2119187

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Um efeito colateral observado nos casos tratados com extrações é a instabilidade do fechamento ortodôntico do espaço. Objetivo: O objetivo do presente estudo foi investigar a influência da invaginação gengival, da presença de terceiros molares e do padrão facial na estabilidade do fechamento ortodôntico dos locais de extração na arcada superior. Métodos: Noventa e nove indivíduos (41 homens e 58 mulheres) com má oclusão de Classe I tratados com extração de quatro pré-molares foram avaliados. A reabertura dos locais de extração e as invaginações gengivais foram avaliadas nos modelos dentários digitalizados nos estágios pós-tratamento e um ano pós-tratamento (idade média de 16,1 anos). A presença dos terceiros molares foi avaliada em radiografias panorâmicas de um ano pós-tratamento, e o padrão facial (SN.GoGn) foi avaliado nas radiografias laterais iniciais. Análise de regressão logística múltipla foi utilizada para estimar a influência das variáveis independentes citadas na frequência de reabertura do espaço de extração. Resultados: A reabertura do espaço foi observada em 20,20% dos sujeitos um ano após a remoção do aparelho. Invaginações gengivais estiveram presentes em 25,73% dos quadrantes após a remoção do aparelho e em 22,80% após um ano pós-tratamento. O SN.GoGn pré-tratamento médio foi de 35,64 graus (DP = 5,26). Não foi observada influência significativa das três variáveis independentes sobre a instabilidade do fechamento do local de extração. Conclusões: A presença de invaginações gengivais, terceiros molares e padrão de crescimento facial não parece influenciar na reabertura dos locais de extração maxilar.

ABSTRACT Introduction: A side effect observed in cases treated with extractions is the instability of orthodontic space closure. Objective: The aim of this study was to investigate the influence of gingival invagination, presence of third molars and facial pattern, on the stability of orthodontic space-closure in the maxillary arch. Methods: Ninety-nine subjects (41 male and 58 female) with Class I malocclusion treated with four premolars extraction were evaluated. Extraction sites reopening and gingival invaginations were evaluated in scanned dental models in the posttreatment and 1-year posttreatment stages (mean age 16.1 years). Third molars presence was evaluated at 1-year posttreatment panoramic radiographs, and the facial pattern (SN.GoGn) was evaluated in the initial lateral headfilms. Multiple logistic regression analysis was used to estimate the influence of the aforementioned independent variables on the frequency of extraction space reopening. Results: Space reopening was observed in 20.20% of the subjects 1-year post-debonding. Gingival invaginations were present in 25.73% of quadrants after debonding and in 22.80% 1-year posttreatment. The mean pre-treatment SN.GoGn was 35.64 degrees (SD=5.26). No significant influence was observed of the three independent variables on the instability of extraction site closure. Conclusions: The presence of gingival invaginations, third molars and facial growth pattern do not seem to influence maxillary extraction sites reopening.

https://doi.org/10.1590/2177-6709.26.2.e2119187.oar 263 downloads

The influence of 3x3 bonded retainer on anterior crowding relapse in mandibular incisor extraction cases
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BERBERT, Marcelo

; COTRIN, Paula

; OLIVEIRA, Renata Cristina Gobbi de

; OLIVEIRA, Ricardo Gobbi de

; VALARELLI, Fabricio Pinelli

; FREITAS, Marcos Roberto de

; FREITAS, Karina Maria Salvatore

Dental Press Journal of Orthodontics

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2021, Volume 26 N. 6 elocation e212081

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Avaliar a influência da contenção fixa 3x3 no apinhamento anterior em casos tratados com extração de incisivo inferior. Métodos: A amostra foi constituída por arquivos ortodônticos das fases pré-tratamento, pós-tratamento e avaliação em longo prazo, de 16 pacientes (10 mulheres e 6 homens) portadores de má oclusão de Classe I tratados com a extração de um único incisivo inferior. As idades médias (± DP) pré-tratamento, pós-tratamento e na avaliação em longo prazo foram 23,45 ± 9,14 anos, 25,50 ± 8,95 anos e 30,11 ± 8,59 anos, respectivamente. O tempo médio (± DP) de tratamento e de acompanhamento em longo prazo foi 2,05 ± 0,45 anos e 4,60 ± 1,85 anos, respectivamente. Nos modelos de gesso, foram avaliados o Índice de Irregularidade de Little e as distâncias interdentárias. A amostra foi dividida em dois subgrupos, de acordo com a presença da contenção fixa 3x3 na avaliação em longo prazo. Resultados: O grupo sem contenção fixa apresentou uma maior recidiva na avaliação em longo prazo, quando comparado com o grupo que tinha a contenção fixa. Conclusão: Houve uma recidiva significativa nos casos tratados com extração de incisivo, na avaliação em longo prazo. O subgrupo sem contenção fixa 3x3 mostrou uma recidiva significativa em longo prazo, quando comparado ao grupo com contenção.

ABSTRACT Objective: To evaluate the 3x3 bonded retainer influence on the mandibular anterior crowding in cases treated with mandibular incisor extraction Methods: The sample comprised pretreatment, posttreatment and follow-up orthodontic records of 16 subjects (10 females and 6 males) with Class I malocclusion treated with extraction of a single mandibular incisor. The mean ages (± SD) at pretreatment, posttreatment and follow-up evaluation were 23.45 ± 9.14 years, 25.50 ± 8.95 years and 30.11 ± 8.59 years, respectively. The mean (± SD) treatment time and posttreatment evaluation time were 2.05 ± 0.45 years and 4.60 ± 1.85 years , respectively. Little irregularity index and interdental widths were evaluated using dental casts. The sample was divided into two subgroups, according to the presence of the 3x3 bonded retainer at follow-up. Results: The subgroup without 3x3 bonded retainer presented a greater relapse at the follow-up, when compared to 3x3 bonded retainer subgroup. Conclusion: There was a significant relapse in cases treated with mandibular incisor extraction at follow-up. The subgroup without 3x3 bonded retainer showed a significant relapse at the follow-up when compared to the retainer group.

https://doi.org/10.1590/2177-6709.26.6.e212081.oar 1 downloads

10.

Clostridium perfringens α and β recombinant toxoids in equine immunization
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Freitas, Nayra F.Q.R.

; Barbosa, José D.

; Otaka, Denis Y.

; Ferreira, Marcos Roberto A.

; Rodrigues, Rafael R.

; Moreira Jr, Clóvis

; Conceição, Fabricio R.

; Salvarani, Felipe M.

Pesquisa Veterinária Brasileira

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oct 2020, Volume 40 N. 10 Pages 776 - 780

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: Clostridium perfringens é considerado um dos principais agentes causadores de enterocolites superagudas, geralmente fatais na espécie equina, devido à ação da toxina β, além de ser responsável por causar quadros graves de mionecrose, pela ação da toxina α. A grande importância desses agentes na equinocultura, deve-se a elevada mortalidade e a inexistência de vacinas, principal forma de prevenção, que garantam a imunização dessa espécie animal. O objetivo deste trabalho foi avaliar três diferentes concentrações (100, 200 e 400μg) dos toxóides recombinantes α e β de C. perfringens na imunização de equinos, bem como comparar com um grupo vacinado com um toxóide comercial. A vacina comercial não se mostrou capaz de estimular uma resposta imune e a vacina recombinante foi capaz de induzir resposta imune humoral satisfatória em equinos vacinados, provando ser uma alternativa profilática para infecção por C. Perfringens.

ABSTRACT: Clostridium perfringens is considered one of the main causative agents of superacute enterocolitis, usually fatal in the equine species, due to the action of the β toxin, and is responsible for causing severe myonecrosis, by the action of the α toxin. The great importance of this agent in the equine economy is due to high mortality and lack of vaccines, which are the main form of prevention, which guarantee the immunization of this animal species. The aim of this study was to evaluate three different concentrations (100, 200 and 400μg) of C. perfringens α and β recombinant toxoids in equine immunization and to compare with a group vaccinated with a commercial toxoid. The commercial vaccine was not able to stimulate an immune response and the recombinant vaccine was able to induce satisfactory humoral immune response in vaccinated horses, proving to be an alternative prophylactic for C. perfringens infection.

https://doi.org/10.1590/1678-5150-pvb-6677 559 downloads

11.

Pre-harvest desiccation in biomass sorghum with herbicides
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Barros, Angélica Fátima de

; Pimentel, Leonardo Duarte

; Freitas, Francisco Cláudio Lopes de

; Cecon, Paulo Roberto

; Tomaz, Adriano Cirino

; Biesdorf, Evandro Marcos

Revista Ceres

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oct 2020, Volume 67 N. 5 Pages 337 - 344

Abstract: En | Text: En | PDF: En

ABSTRACT The purpose of this study was to assess the effect of different herbicide treatments on moisture removal and calorific power of biomass sorghum for co-generation of electric energy through burning. The experiment was conducted in randomized complete block design with four replicates per treatment and a 6x4 factorial scheme (six herbicide treatments x four intervals between spraying and harvesting). The herbicide treatments were: two different doses of glyphosate (1.92 kg a.i. ha-1 and 3.84 Kg a.i. ha-1), paraquat (0.4 Kg a.i. ha-1), a commercial mixture of paraquat + diuron (0.6 + 0.3 Kg a.i. ha-1), glufosinate-ammonium (0.8 Kg a.i. ha-1) and control (unsprayed). The intervals between spraying and harvesting assessed were 7, 14, 21 and 28 days after desiccation (DAD). It was assessed: the number of leaves per plant, moisture content of leaves, panicles, culm and whole ground plants and Superior Calorific Power (SCP). The herbicides paraquat and paraquat + diuron promotes defoliation, after 14 DAD. Glyphosate, paraquat, paraquat + diuron and glufosinate-ammonium reduce leaf and panicle moisture, despite only glyphosate reduces moisture in the culm. The herbicides do not affect the SCP of biomass sorghum. Therefore, the herbicides, especially glyphosate, have high potential for pre-harvest desiccation in biomass sorghum.

https://doi.org/10.1590/0034-737x202067050001 532 downloads

12.

[SciELO Preprints] - National Health Survey 2019: history, methods and perspectives
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Stopa, Sheila Rizzato Szwarcwald, Célia Landmann Oliveira, Max Moura de Gouvea, Ellen de Cassia Dutra Pozzetti Vieira, Maria Lúcia França Pontes Freitas, Marcos Paulo Soares de Sardinha, Luciana Monteiro Vasconcelos Macário, Eduardo Marques Cruz, Danielle Keylla Alencar Silva, Luiza Eunice Sá da Oliveira, Patrícia Pereira Vasconcelos de Freitas, Paula Carvalho de Brito, Valéria Cristina de Albuquerque Tierling, Vera Lúcia Pereira, Vinícius Oliveira de Moura Damacena, Giseli Nogueira Júnior, Paulo Roberto Borges de Souza Vargas, Marcia Águas, Marina Ferreira Fortes

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Publication date: 2020-08-25

Abstract: En Pt

This article presents the history and construction of the National Health Survey (PNS) 2019, a household survey conducted in partnership with the Brazilian Institute of Geography and Statistics. The objective was to provide the country with information on the determinants, conditions and health needs of the Brazilian population. The expected sample was 108,525 households, considering a non-response rate of 20%. The questionnaire had three parts: (i) regarding the household; (ii) to all residents of the household, focusing on the collection of socioeconomic and health information; and (iii) aimed at the selected resident (15 years or more) for whom lifestyles, chronic diseases, violence, among other topics were investigated, and anthropometric measures (sub-sample) were measured. The PNS information will serve as a basis for the (re)formulation of health policies, as well as support for existing actions and programs of the Unified Health System.

Este artigo apresenta o histórico e a construção da Pesquisa Nacional de Saúde (PNS) 2019, inquérito de base domiciliar realizado em parceria com a fundação Instituto Brasileiro de Geografia e Estatística. O objetivo da PNS 2019 foi dotar o país de informações sobre os determinantes, condicionantes e necessidades de saúde da população brasileira. A amostra prevista foi de 108.525 domicílios particulares, considerando-se uma taxa de não resposta de 20%. Seu questionário continha três partes, orientadas para (i) o domicílio, (ii) todos os moradores do domicílio, com enfoque na coleta de informações socioeconômicas e de saúde, e (iii) o morador selecionado (idade ≥15 anos), sobre o qual investigou-se estilos de vida, doenças crônicas, violências, entre outros temas, e aferiu-se medidas antropométricas (subamostra). As informações da PNS 2019 servirão de base para a (re)formulação de políticas de saúde e subsídio a ações e programas existentes do Sistema Único de Saúde.

https://doi.org/10.1590/SciELOPreprints.1142

13.

Ingestive behavior, ruminal and blood kinetics in lambs fed cow cheese whey
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GUEDES, Luciana Freitas

; PRIMO, Tatiana Santos

; VASCONCELOS, Ângela Maria de

; POMPEU, Roberto Cláudio Fernandes Franco

; NEIVA, José Neuman Miranda

; COSTA, Clésio dos Santos

; OLIVEIRA, Delano de Sousa

; ROGÉRIO, Marcos Cláudio Pinheiro

Revista Brasileira de Saúde e Produção Animal

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2020, Volume 21 elocation e2121192020

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivou-se avaliar a inclusão de soro de queijo bovino (SQB) na dieta para ovinos sobre o comportamento ingestivo, os parâmetros ruminais e sanguíneos. Vinte ovinos mestiços, machos, não castrados, com 25 kg de peso corporal foram distribuídos em quatro dietas: dieta controle (composta por milho, farelo de soja e silagem de pasto nativo) e as dietas teste (dieta controle + inclusão de SQB em níveis crescentes 1,6; 2,7 e 4,0% na MS), em um delineamento inteiramente ao acaso com quatro tratamentos e cinco repetições. A comparação de médias foi realizada pelo teste Tukey e foram testadas as correlações de Pearson entre as variáveis. Também foi feita a análise de regressão para os dados provenientes da coleta de líquido ruminal e de sangue. As avaliações de comportamento foram feitas em um intervalo de 24 horas em medições realizadas a cada cinco minutos. A inclusão de SQB na dieta não comprometeu o pH ruminal, mas promoveu a queda nos tempos de ruminação e de alimentação, ocasionando também menor número de bolos ruminais e menor número de mastigações merícicas. A menor concentração de nitrogênio amoniacal e proteínas totais foram encontradas nos ovinos que receberam a dieta com 4% de inclusão de SQB. Entretanto, esses valores ficaram dentro do padrão estabelecido para crescimento microbiano. O SQB é uma potencial alternativa proteica na alimentação de ovinos por não interferir no consumo de nutrientes, nos parâmetros ruminais e sanguíneos, e favorecer o balanço positivo de nitrogênio.

ABSTRACT The objective of this study was to evaluate the inclusion of cow cheese whey (CCW) in the diet for lambs on the ingestive behavior, ruminal and blood parameters. Twenty crossbred, male, non-castrated lambs with 25 kg body weight were assigned to four treatments: control diet (composed of corn, soybean meal and native pasture silage) and test diets (control diet + inclusion of CCW in increasing levels of 1.6, 2.7 and 4.0% in DM), in a completely randomized design with four treatments and five replications. Means were compared by Tukey’s test, and the strength of association between variables was tested by Pearson’s correlation. Regression analysis was also performed for data from the collection of ruminal fluid and blood. Behavioral assessments were made at a 24-hour interval in measurements taken every five minutes. The inclusion of CCW in the diet did not impair ruminal pH, but promoted a decrease in rumination and feeding times, also causing a lower number of cuds and a lower number of cud chews. The lowest concentration of ammonia nitrogen and total protein were found in lambs receiving the diet with 4% CCW. However, these values were within the range recommended for microbial growth. CCW is a potential protein alternative in lambs feed as it does not interfere with nutrient intake, ruminal and blood parameters, and favors a positive nitrogen balance.

https://doi.org/10.1590/s1519-99402121192020 222 downloads

14.

Snake venoms and purified toxins as biotechnological tools to control Ralstonia solanacearum
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Alves, Rita de Cássia

; Vieira Júnior, José Roberto

; Freire, Tamiris Chaves

; Fonseca, Aline Souza da

; Sangi, Simone Carvalho

; Barbieri, Fábio da Silva

; Rocha, Rodrigo Barros

; Brito, Luciana Gatto

; Pereira, Soraya dos Santos

; Luiz, Marcos Barros

; Freire, Francisco das Chagas Oliveira

; Fernandes, Carla Freire Celedonio

; Soares, Andreimar Martins

; Fernandes, Cléberson de Freitas

Pesquisa Agropecuária Brasileira

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2020, Volume 55 elocation e01756

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: O objetivo deste trabalho foi avaliar a atividade antibacteriana in vitro de venenos e toxinas purificadas de serpentes sobre a bactéria fitopatogênica Ralstonia solanacearum. As avaliações foram realizadas em 17 venenos brutos (13 de Bothrops, 3 de Crotalus e 1 de Lachesis) e sete toxinas (1 de Bothrops e 6 de Crotalus). A atividade antibacteriana foi avaliada em meio MB1 que continha os tratamentos solubilizados (1 μL mL-1). Utilizou-se o total de 100 μL de suspensão bacteriana (8,4 x 109 UFC mL-1). Após incubação a 28°C, avaliou-se o número de colônias bacterianas às 24, 48 e 72 horas após a inoculação. O gel SDS-PAGE a 15% foi usado para analisar o perfil proteico das amostras, tendo-se utilizado 5 μg de proteína no ensaio. Além disso, os valores de concentração inibitória mínima (CIM) e concentração letal (CL50) foram determinados pelo método Probit. Os venenos e as toxinas foram capazes de reduzir mais de 90% do crescimento de R. solanacearum. Esses resultados foram ou equivalentes aos do controle positivo cloranfenicol ou até melhores. Enquanto os valores de CIM variaram de 4,0 a 271,5 μg mL-1, a CL50 variou de 28,5 μg mL-1 a 4,38 mg mL-1. Dez venenos brutos (7 de Bothrops e 3 de Crotalus) e duas toxinas (giroxina e crotamina) são abordagens promissoras para o controle da bactéria fitopatogênica R. solanacearum.

Abstract: The objective of this work was to evaluate the in vitro antibacterial activity of snake venoms and purified toxins on the phytopathogenic bacterium Ralstonia solanacearum. The evaluations were performed with 17 crude venoms (13 from Bothrops, 3 from Crotalus, and 1 from Lachesis) and seven toxins (1 from Bothrops and 6 from Crotalus). Antibacterial activity was assessed in MB1 medium containing solubilized treatments (1 μL mL-1). A total of 100 μL bacterial suspension (8.4 x 109 CFU mL-1) was used. After incubation at 28°C, the number of bacterial colonies at 24, 48, and 72 hours after inoculation was evaluated. SDS-PAGE gel at 15% was used to analyze the protein patterns of the samples, using 5 μg protein of each sample in the assay. Furthermore, the minimum inhibitory concentration (MIC) and lethal concentration (LC50) values were determined by the Probit method. Venoms and toxins were able to reduce more than 90% of R. solanacearum growth. These results were either equivalent to those of the positive control chloramphenicol or even better. While MIC values ranged from 4.0 to 271.5 μg mL-1, LC50 ranged from 28.5 μg mL-1 to 4.38 mg mL-1. Ten crude venoms (7 from Bothrops and 3 from Crotalus) and two purified toxins (gyroxin and crotamine) are promising approaches to control the phytopathogenic bacterium R. solanacearum.

https://doi.org/10.1590/s1678-3921.pab2020.v55.01756 478 downloads

15.

BRAZILIAN SOCIETY OF HEPATOLOGY UPDATED RECOMMENDATIONS FOR DIAGNOSIS AND TREATMENT OF HEPATOCELLULAR CARCINOMA
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CHAGAS, Aline Lopes

; MATTOS, Angelo Alves de

; CARRILHO, Flair José

; BITTENCOURT, Paulo Lisboa

; VEZOZZO, Denise Cerqueira Paranaguá

; HORVAT, Natally

; ROCHA, Manoel de Souza

; ALVES, Venâncio Avancini Ferreira

; CORAL, Gabriela Perdomo

; ALVARES-DA-SILVA, Mario Reis

; BARROS, Fabio Marinho do Rego

; MENEZES, Marcos Roberto

; MONSIGNORE, Lucas Moretti

; COELHO, Fabricio Ferreira

; SILVA, Renato Ferreira da

; SILVA, Rita de Cássia Martins Alves

; BOIN, Ilka de Fatima Santana Ferreira

; D`ALBUQUERQUE, Luiz Augusto Carneiro

; GARCIA, José Huygens Parente

; FELGA, Guilherme Eduardo Gonçalves

; MOREIRA, Airton Mota

; BRAGHIROLI, Maria Ignez Freitas Melro

; HOFF, Paulo Marcelo Gehm

; MELLO, Vivianne Barretto de

; DOTTORI, Mariana Fonseca

; BRANCO, Tiago Pugliese

; SCHIAVON, Leonardo de Lucca

; COSTA, Thaisa de Fátima Almeida

Arquivos de Gastroenterologia

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2020, Volume 57 Suppl. 1 Pages 1 - 20

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O carcinoma hepatocelular (CHC) é uma das principais causas de mortalidade relacionada a câncer no Brasil e no mundo. A Sociedade Brasileira de Hepatologia (SBH) publicou em 2015 suas primeiras recomendações sobre a abordagem do CHC. Desde então, novas evidências sobre o diagnóstico e tratamento do CHC foram relatadas na literatura médica, levando a diretoria da SBH a promover uma reunião monotemática sobre câncer primário de fígado em agosto de 2018 com o intuito de atualizar as recomendações sobre o manejo da neoplasia. Um grupo de experts foi convidado para realizar uma revisão sistemática da literatura e apresentar uma atualização baseada em evidências científicas visando que pudesse nortear a prática clínica multidisciplinar do CHC. O texto resultante foi submetido a avaliação e aprovação de todos membros da SBH através de sua homepage. O documento atual é a versão final que contêm as recomendações atualizadas e revisadas da SBH.

ABSTRACT Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. The Brazilian Society of Hepatology (SBH) published in 2015 its first recommendations about the management of HCC. Since then, new data have emerged in the literature, prompting the governing board of SBH to sponsor a single-topic meeting in August 2018 in São Paulo. All the invited experts were asked to make a systematic review of the literature reviewing the management of HCC in subjects with cirrhosis. After the meeting, all panelists gathered together for the discussion of the topics and the elaboration of updated recommendations. The text was subsequently submitted for suggestions and approval of all members of the Brazilian Society of Hepatology through its homepage. The present manuscript is the final version of the reviewed manuscript containing the recommendations of SBH.

https://doi.org/10.1590/s0004-2803.202000000-20 4088 downloads

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